FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Adriano Aguzzi

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Anatomy

Procedures

Phenomena

Blotting, Western

Co-author Network

Publications

TOP 3
Jana Sponarova; Gunilla T Westermark; Charlotte Whicher; Nathalie Frei; Veronika Kana; Mario Nuvolone; Petra Schwarz; Adriano Aguzzi
Efficient amyloid a clearance in the absence of immunoglobulins and complement factors.
Tracy O'Connor; Adriano Aguzzi
Prions and lymphoid organs: solved and remaining mysteries.
Adriano Aguzzi; Ben A Barres; Mariko L Bennett
Microglia: scapegoat, saboteur, or something else?

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Adriano Aguzzi (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Jana Sponarova; Gunilla T Westermark; Charlotte Whicher; Nathalie Frei; Veronika Kana; Mario Nuvolone; Petra Schwarz; Adriano Aguzzi
Efficient amyloid a clearance in the absence of immunoglobulins and complement factors.
The American journal of pathology 2013;182(4):1297-307.
2013: Tracy O'Connor; Adriano Aguzzi
Prions and lymphoid organs: solved and remaining mysteries.
Prion 2013;7(2):157-63.
2013: Adriano Aguzzi; Ben A Barres; Mariko L Bennett
Microglia: scapegoat, saboteur, or something else?
Science (New York, N.Y.) 2013;339(6116):156-61.
2013: Karen H Ashe; Adriano Aguzzi
Prions, prionoids and pathogenic proteins in Alzheimer disease.
Prion 2013;7(1):55-9.
2012: Megan Larson; Adriano Aguzzi; Fatou Amar; David A Bennett; Mario Nuvolone; Julie A Schneider; Mathew A Sherman; Sylvain E Lesné
The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(47):16857-71a.
2012: Pravas Kumar Baral; Adriano Aguzzi; Nat Kav; Magdalini Polymenidou; Muhammad Hafiz Rahman; Mridula Swayampakula; Barbara Wieland; Michael N G James
Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 11):1501-12.
2012: Gitta M Seleznik; Emma Slack; Li-Kang Sun; Achim Weber; Adriano Aguzzi; Hans-Joachim Anders; Eliane Angst; Melek Canan Arkan; Maria Luisa Balmer; Jeffrey L Browning; Rolf Graf; Johannes Haybaeck; Yoichi Hiasa; Teru Kumagi; Carolin Lackner; Maciej Lech; Andrew MacPherson; Markus G Manz; Donal McHugh; Alexander Mildner; Aurel Perren; Marco Prinz; Theresia Reding; Stephan Regenass; Franziska Romrig; Thomas Rülicke; Yasuyuki Saito; Stephan Segerer; Mathias Heikenwalder
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.
Gastroenterology 2012;143(5):1361-74.
2012: Nicholas H Varvel; Christian Liebig; Richard M Ransohoff; Dietmar R Thal; Adriano Aguzzi; Frank Baumann; Andrea Bosch; Bianca Brawek; Israel F Charo; Olga Garaschuk; Stefan A Grathwohl; Frank L Heppner; Mathias Jucker
Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):18150-5.
2012: Katharina Stoeck; Cornelia M van Duijn; Adriano Aguzzi; Miguel Calero; Joanna Gawinecka; Alison Green; Andre Karch; Richard Knight; Jerzy Kulczycki; Anna Ladogana; Jean-Louis Laplanche; Eva Mitrova; Katell Peoc'h; Maurizio Pocchiari; Albert Saiz; Pascual Sanchez-Juan; Raquel Sanchez-Valle; Gabi Schelzke; Theodoros Sklaviadis; Dana Slivarichova; Inga Zerr
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years.
Brain : a journal of neurology 2012;135(Pt 10):3051-61.
2012: Sofie Nyström; Adriano Aguzzi; Simone Hornemann; Rajesh Mishra; K Peter R Nilsson; Per Hammarström
Multiple substitutions of methionine 129 in human prion protein reveal its importance in the amyloid fibrillation pathway.
The Journal of biological chemistry 2012;287(31):25975-84.
2012: Monika Julia Wolf; Adriano Aguzzi; Judith Bauer; Steffen Boettcher; Lubor Borsig; Roland S Croner; Alexandra Hoos; Markus Knust; Andreas Konrad; Matthias Lang; Markus G Manz; Holger Moch; Manolis Pasparakis; Marco Prinz; Christoph Schneider; Nicole Simonavicius; Michael Stürzl; Geert van Loo; Achim Weber; Mathias Heikenwalder
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway.
Cancer cell 2012;22(1):91-105.
2012: Nike Kräutler; Doreen Lemm; José B Oliveira-Martins; Dushan Perera; Petra Schwarz; Michelle Tallquist; Yinghua Tian; Ulrich Wagner; Caihong Zhu; Annika Armulik; Robert Brink; Jeffrey L Browning; Thorsten Buch; Mathias Heikenwalder; Mario Hermann; Veronika Kana; Jan Kranich; Adriano Aguzzi
Follicular dendritic cells emerge from ubiquitous perivascular precursors.
Cell 2012;150(1):194-206.
2012: Adriano Aguzzi; Jeppe Falsig
Prion propagation, toxicity and degradation.
Nature neuroscience 2012;15(7):936-9.
2012: Ilan Margalith; K Peter R Nilsson; Sofie Nyström; Petra Schwarz; Tiziana Sonati; Carlo Suter; Cinzia Tiberi; Eric Whitters; Alice Yam; Andreas Aslund; Boris Ballmer; Jeppe Falsig; Per Hammarström; Simone Hornemann; Adriano Aguzzi
Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates.
The Journal of biological chemistry 2012;287(23):18872-87.
2012: Jeppe Falsig; Uli S Herrmann; Bei Li; Pawel P Liberski; Dino Saban; Tiziana Sonati; Karina Arroyo; Boris Ballmer; Adriano Aguzzi
Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures.
PLoS pathogens 2012;8(11):e1002985.
2012: Mario Hermann; J Keith Joung; Cyd Khayter; Morgan L Maeder; Adriano Aguzzi; Burkhard Becher; Thorsten Buch; Kurt Bürki; Kyle Rector; Joseph Ruiz; Pawel Pelczar
Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos.
PloS one 2012;7(9):e41796.
2012: Tracy O'Connor; Petra Schwarz; Jana Sponarova; Nathalie Frei; Mathias Heikenwalder; Adriano Aguzzi
Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes.
PLoS pathogens 2012;8(8):e1002867.
2012: Donal McHugh; Tracy O'Connor; Juliane Bremer; Adriano Aguzzi
ZyFISH: a simple, rapid and reliable zygosity assay for transgenic mice.
PloS one 2012;7(5):e37881.
2012: Adriano Aguzzi; Caihong Zhu
Five questions on prion diseases.
PLoS pathogens 2012;8(5):e1002651.
2012: Hans H Jung; Maria Grazia Spillantini; Johannes Streffer; Adriano Aguzzi; Juliane Bremer; Peter Brugger; R Anthony Crowther; Christine Van Broeckhoven; Kanwar Virdee; Markus Tolnay
Phenotypic variation of autosomal-dominant corticobasal degeneration.
European neurology 2012;67(3):142-50.
2011: Pravas Kumar Baral; Adriano Aguzzi; Nat Kav; Magdalini Polymenidou; Mridula Swayampakula; Barbara Wieland; Michael N G James
Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 10):1211-3.
2011: Christina J Sigurdson; Olivia Winson; Kurt Wüthrich; Cyrus Bett; Simone Hornemann; Shivanjali Joshi-Barr; Giuseppe Manco; Ilan Margalith; K Peter R Nilsson; David Peretz; Alex Raeber; Thomas Rülicke; Petra Schwarz; Adriano Aguzzi
Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(39):13840-7.
2011: Lothar Stitz; Adriano Aguzzi
Aerosols: an underestimated vehicle for transmission of prion diseases?
Prion 2011;5(3):138-41.
2011: Anne K Schütz; Alice Soragni; Adriano Aguzzi; Anja Böckmann; Matthias Ernst; Simone Hornemann; Beat H Meier
The amyloid-Congo red interface at atomic resolution.
Angewandte Chemie (International ed. in English) 2011;50(26):5956-60.
2011: Iva Hafner Bratkovič; Romina Bester; Primoz Pristovsek; Lars Gaedtke; Peter Veranic; Jernej Gaspersic; Mateja Mancek-Keber; Matevz Avbelj; Magdalini Polymenidou; Christian Julius; Adriano Aguzzi; Ina Vorberg; Roman Jerala
Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion.
The Journal of biological chemistry 2011;286(14):12149-56.
2011: Jacob I Ayers; Charles R Schutt; Ronald A Shikiya; Adriano Aguzzi; Anthony E Kincaid; Jason C Bartz
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease.
PLoS pathogens 2011;7(3):e1001317.
2011: Magdalini Polymenidou; Stefan Prokop; Hans H Jung; Ekkehard Hewer; David Peretz; Rita Moos; Markus Tolnay; Adriano Aguzzi
Atypical prion protein conformation in familial prion disease with PRNP P105T mutation.
Brain pathology (Zurich, Switzerland) 2011;21(2):209-14.
2011: Johannes Haybaeck; Mathias Heikenwalder; Britta Klevenz; Petra Schwarz; Ilan Margalith; Claire Bridel; Kirsten Mertz; Elizabeta Zirdum; Benjamin Petsch; Thomas J Fuchs; Lothar Stitz; Adriano Aguzzi
Aerosols transmit prions to immunocompetent and immunodeficient mice.
PLoS pathogens 2011;7(1):e1001257.
2011: Ciriaco Ligios; Maria Giovanna Cancedda; Antonello Carta; Cinzia Santucciu; Caterina Maestrale; Francesca Demontis; Mariangela Saba; Cristiana Patta; James C DeMartini; Adriano Aguzzi; Christina J Sigurdson
Sheep with scrapie and mastitis transmit infectious prions through the milk.
Journal of virology 2011;85(2):1136-9.
2010: Jan Kranich; Nike Kräutler; Jeppe Falsig; Boris Ballmer; Shulei Li; Gregor Hutter; Petra Schwarz; Rita Moos; Christian Julius; Gino Miele; Adriano Aguzzi
Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner.
The Journal of experimental medicine 2010;207(10):2271-81.
2010: Adriano Aguzzi; Nike J Krautler
Characterizing follicular dendritic cells: A progress report.
European journal of immunology 2010;40(8):2134-8.
2010: Anna Maria Calella; Mélissa Farinelli; Mario Nuvolone; Osvaldo Mirante; Rita Moos; Jeppe Falsig; Isabelle M Mansuy; Adriano Aguzzi
Prion protein and Abeta-related synaptic toxicity impairment.
EMBO molecular medicine 2010;2(8):306-14.
2010: Christina J Sigurdson; K Peter R Nilsson; Simone Hornemann; Giuseppe Manco; Natalia Fernández-Borges; Petra Schwarz; Joaquín Castilla; Kurt Wüthrich; Adriano Aguzzi
A molecular switch controls interspecies prion disease transmission in mice.
The Journal of clinical investigation 2010;120(7):2590-9.
2010: Martine M Mirrione; Dorothy K Konomos; Iordanis Gravanis; Stephen L Dewey; Adriano Aguzzi; Frank L Heppner; Stella E Tsirka
Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.
Neurobiology of disease 2010;39(1):85-97.
2010: Atsushi Kobayashi; Nobuyuki Sakuma; Yuichi Matsuura; Shirou Mohri; Adriano Aguzzi; Tetsuyuki Kitamoto
Experimental verification of a traceback phenomenon in prion infection.
Journal of virology 2010;84(7):3230-8.
2010: Adriano Aguzzi; Tracy O'Connor
Protein aggregation diseases: pathogenicity and therapeutic perspectives.
Nature reviews. Drug discovery 2010;9(3):237-48.
2010: Juliane Bremer; Frank Baumann; Cinzia Tiberi; Carsten Wessig; Heike Fischer; Petra Schwarz; Andrew D Steele; Klaus V Toyka; Klaus-Armin Nave; Joachim Weis; Adriano Aguzzi
Axonal prion protein is required for peripheral myelin maintenance.
Nature neuroscience 2010;13(3):310-8.
2010: K Peter R Nilsson; Kristian Ikenberg; Andreas Aslund; Sophia Fransson; Peter Konradsson; Christoph Röcken; Holger Moch; Adriano Aguzzi
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
The American journal of pathology 2010;176(2):563-74.
2010: Rowayda Peters; Monika J Wolf; Maries van den Broek; Mario Nuvolone; Stefanie Dannenmann; Bruno Stieger; Reto Rapold; Daniel Konrad; Arnold Rubin; Joseph R Bertino; Adriano Aguzzi; Mathias Heikenwalder; Alexander K Knuth
Efficient generation of multipotent mesenchymal stem cells from umbilical cord blood in stroma-free liquid culture.
PloS one 2010;5(12):e15689.
2010: Susanne Krasemann; Melanie Neumann; Markus Geissen; Walter Bodemer; Franz-Josef Kaup; Walter Schulz-Schaeffer; Nathalie Morel; Adriano Aguzzi; Markus Glatzel
Preclinical deposition of pathological prion protein in muscle of experimentally infected primates.
PloS one 2010;5(11):e13906.
2010: Juliane Bremer; Tracy O'Connor; Cinzia Tiberi; Hubert Rehrauer; Joachim Weis; Adriano Aguzzi
Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.
PloS one 2010;5(8):e12450.
2010: José B Oliveira-Martins; Sei-ichi Yusa; Anna Maria Calella; Claire Bridel; Frank Baumann; Paolo Dametto; Adriano Aguzzi
Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations.
PloS one 2010;5(2):e9107.
2009: Adriano Aguzzi; Lawrence Rajendran
The transcellular spread of cytosolic amyloids, prions, and prionoids.
Neuron 2009;64(6):783-90.
2009: Tuomas P J Knowles; Christopher Waudby; Glyn L Devlin; Samuel I A Cohen; Adriano Aguzzi; Michele Vendruscolo; Eugene M Terentjev; Mark E Welland; Christopher M Dobson
An analytical solution to the kinetics of breakable filament assembly.
Science (New York, N.Y.) 2009;326(5959):1533-7.
2009: Stefan A Grathwohl; Roland E Kälin; Tristan Bolmont; Stefan Prokop; Georg Winkelmann; Stephan A Kaeser; Jörg Odenthal; Rebecca Radde; Therese Eldh; Sam Gandy; Adriano Aguzzi; Matthias Staufenbiel; Paul Mathews; Hartwig Wolburg; Frank L Heppner; Mathias Jucker
Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia.
Nature neuroscience 2009;12(11):1361-3.
2009: Johannes Haybaeck; Nicolas Zeller; Monika Julia Wolf; Achim Weber; Ulrich Wagner; Michael Odo Kurrer; Juliane Bremer; Giandomenica Iezzi; Rolf Graf; Pierre-Alain Clavien; Robert Thimme; Hubert Blum; Sergei A Nedospasov; Kurt Zatloukal; Muhammad Ramzan; Sandra Ciesek; Thomas Pietschmann; Patrice N Marche; Michael Karin; Manfred Kopf; Jeffrey L Browning; Adriano Aguzzi; Mathias Heikenwalder
A lymphotoxin-driven pathway to hepatocellular carcinoma.
Cancer cell 2009;16(4):295-308.
2009: Adriano Aguzzi; Anna Maria Calella
Prions: protein aggregation and infectious diseases.
Physiological reviews 2009;89(4):1105-52.
2009: Anna Ladogana; Pascual Sanchez-Juan; Eva Mitrová; Alison Green; Natividad Cuadrado-Corrales; Raquel Sánchez-Valle; Silvia Koscova; Adriano Aguzzi; Theodoros Sklaviadis; Jerzy Kulczycki; Joanna Gawinecka; Albert Saiz; Miguel Calero; Cornelia M van Duijn; Maurizio Pocchiari; Richard Knight; Inga Zerr
Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies.
Journal of neurology 2009;256(10):1620-8.
2009: Andreas Aslund; Christina J Sigurdson; Therése Klingstedt; Stefan Grathwohl; Tristan Bolmont; Dara L Dickstein; Eirik Glimsdal; Stefan Prokop; Mikael Lindgren; Peter Konradsson; David M Holtzman; Patrick R Hof; Frank L Heppner; Sam Gandy; Mathias Jucker; Adriano Aguzzi; Per Hammarström; K Peter R Nilsson
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.
ACS chemical biology 2009;4(8):673-84.
2009: Mario Nuvolone; Adriano Aguzzi; Mathias Heikenwalder
Cells and prions: a license to replicate.
FEBS letters 2009;583(16):2674-84.
2009: Yvonne S Eisele; Tristan Bolmont; Mathias Heikenwalder; Franziska Langer; Laura H Jacobson; Zheng-Xin Yan; Klaus Roth; Adriano Aguzzi; Matthias Staufenbiel; Lary Walker; Mathias Jucker
Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12926-31.
2009: Adriano Aguzzi
Cell biology: Beyond the prion principle.
Nature 2009;459(7249):924-5.
2009: Adriano Aguzzi; Andrew D Steele
Prion topology and toxicity.
Cell 2009;137(6):994-6.
2009: Brent Race; Kimberly Meade-White; Richard Race; Frank Baumann; Adriano Aguzzi; Bruce Chesebro
Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein.
Experimental neurology 2009;217(2):347-52.
2009: Alexis Nazabal; Simone Hornemann; Adriano Aguzzi; Renato Zenobi
Hydrogen/deuterium exchange mass spectrometry identifies two highly protected regions in recombinant full-length prion protein amyloid fibrils.
Journal of mass spectrometry : JMS 2009;44(6):965-77.
2009: Michael Weller; Adriano Aguzzi
Movement disorders reveal Creutzfeldt-Jakob disease.
Nature reviews. Neurology 2009;5(4):185-6.
2009: Christina J Sigurdson; Mathias Heikenwalder; Giuseppe Manco; Manja Barthel; Petra Schwarz; Bärbel Stecher; Nike Kräutler; Wolf-Dietrich Hardt; Burkhardt Seifert; Andrew J S MacPherson; Irène Corthesy; Adriano Aguzzi
Bacterial colitis increases susceptibility to oral prion disease.
The Journal of infectious diseases 2009;199(2):243-52.
2009: Stefan Baenziger; Mathias Heikenwalder; Pål Johansen; Erika Schlaepfer; Ursula Hofer; Regina C Miller; Simone Diemand; Kenya Honda; Thomas M Kundig; Adriano Aguzzi; Roberto F Speck
Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology.
Blood 2009;113(2):377-88.
2009: Christina J Sigurdson; K Peter R Nilsson; Simone Hornemann; Mathias Heikenwalder; Giuseppe Manco; Petra Schwarz; David Ott; Thomas Rülicke; Pawel P Liberski; Christian Julius; Jeppe Falsig; Lothar Stitz; Kurt Wüthrich; Adriano Aguzzi
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):304-9.
2009: Juliane Bremer; Mathias Heikenwalder; Johannes Haybaeck; Cinzia Tiberi; Nike Kräutler; Michael O Kurrer; Adriano Aguzzi
Repetitive immunization enhances the susceptibility of mice to peripherally administered prions.
PloS one 2009;4(9):e7160.
2009: Frank Baumann; Jens Pahnke; Ivan Radovanovic; Thomas Rülicke; Juliane Bremer; Markus Tolnay; Adriano Aguzzi
Functionally relevant domains of the prion protein identified in vivo.
PloS one 2009;4(9):e6707.
2009: Dorothea Rutishauser; Kirsten D Mertz; Rita Moos; Erich Brunner; Thomas Rülicke; Anna Maria Calella; Adriano Aguzzi
The comprehensive native interactome of a fully functional tagged prion protein.
PloS one 2009;4(2):e4446.
2009: Jessica Ruegger; Katharina Stoeck; Lorenz Amsler; Thomas Blaettler; Marcel Zwahlen; Adriano Aguzzi; Markus Glatzel; Klaus Hess; Tobias Eckert
A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001-2004.
BMC public health 2009;9():18.
2008: Jeppe Falsig; K Peterr Nilsson; Tuomas P J Knowles; Adriano Aguzzi
Chemical and biophysical insights into the propagation of prion strains.
HFSP journal 2008;2(6):332-41.
2008: Danica Chen; Andrew D Steele; Gregor Hutter; Joanne Bruno; Arvind Govindarajan; Erin Easlon; Su-Ju Lin; Adriano Aguzzi; Susan Lindquist; Leonard Guarente
The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration.
Experimental gerontology 2008;43(12):1086-93.
2008: Adriano Aguzzi
Staining, straining and restraining prions.
Nature neuroscience 2008;11(11):1239-40.
2008: Harald Seeger; Christian Julius; Costantino Cozzari; Anna Maria Calella; Maurizio Dattilo; Adriano Aguzzi
Prion depletion and preservation of biological activity by preparative chaotrope ultracentrifugation.
Biologicals : journal of the International Association of Biological Standardization 2008;36(6):403-11.
2008: Katharina Stoeck; Klaus Hess; Lorenz Amsler; Tobias Eckert; Dieter Zimmermann; Adriano Aguzzi; Markus Glatzel
Heightened incidence of sporadic Creutzfeldt-Jakob disease is associated with a shift in clinicopathological profiles.
Journal of neurology 2008;255(10):1464-72.
2008: David Ott; Cornelia Taraborrelli; Adriano Aguzzi
Novel dominant-negative prion protein mutants identified from a randomized library.
Protein engineering, design & selection : PEDS 2008;21(10):623-9.
2008: Andrew D Steele; Gregor Hutter; Walker S Jackson; Frank L Heppner; Andrew W Borkowski; Oliver D King; Gregory J Raymond; Adriano Aguzzi; Susan Lindquist
Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13626-31.
2008: Jan Kranich; Nike Kräutler; Ernst Heinen; Magdalini Polymenidou; Claire Bridel; Anita Schildknecht; Christoph Huber; Marie H Kosco-Vilbois; Rolf M Zinkernagel; Gino Miele; Adriano Aguzzi
Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8.
The Journal of experimental medicine 2008;205(6):1293-302.
2008: Mathias Heikenwalder; Marco Prinz; Nicolas Zeller; Karl S Lang; Tobias Junt; Simona Rossi; Alexei Tumanov; Hauke Schmidt; Josef Priller; Lukas Flatz; Thomas Rülicke; Andrew J Macpherson; Georg A Holländer; Sergei A Nedospasov; Adriano Aguzzi
Overexpression of lymphotoxin in T cells induces fulminant thymic involution.
The American journal of pathology 2008;172(6):1555-70.
2008: C Julius; Mathias Heikenwalder; Petra Schwarz; A Marcel; Michael Karin; Marco Prinz; M Pasparakis; Adriano Aguzzi
Prion propagation in mice lacking central nervous system NF-kappaB signalling.
The Journal of general virology 2008;89(Pt 6):1545-50.
2008: Magdalini Polymenidou; Heidi Trusheim; Lena Stallmach; Rita Moos; Christian Julius; Gino Miele; Claudia Lenz-Bauer; Adriano Aguzzi
Canine MDCK cell lines are refractory to infection with human and mouse prions.
Vaccine 2008;26(21):2601-14.
2008: Rosalina Gavín; Jesus Ureña; Alejandra Rangel; Miguel A Pastrana; Jesús R Requena; Eduardo Soriano; Adriano Aguzzi; José A del Río
Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons.
Neurobiology of disease 2008;30(2):243-54.
2008: Nicolas Genoud; David Ott; Nathalie Braun; Marco Prinz; Petra Schwarz; Ueli Suter; Didier Trono; Adriano Aguzzi
Antiprion prophylaxis by gene transfer of a soluble prion antagonist.
The American journal of pathology 2008;172(5):1287-96.
2008: Christine von Poser-Klein; Eckhard Flechsig; Tanja Hoffmann; Petra Schwarz; Harry Harms; Raymond Bujdoso; Adriano Aguzzi; Michael A Klein
Alteration of B-cell subsets enhances neuroinvasion in mouse scrapie infection.
Journal of virology 2008;82(7):3791-5.
2008: Christian Julius; Gregor Hutter; Ulrich Wagner; Harald Seeger; Veronika Kana; Jan Kranich; Peter-Christian Klöhn; Peter Klöhn; Charles Weissmann; Gino Miele; Adriano Aguzzi
Transcriptional stability of cultured cells upon prion infection.
Journal of molecular biology 2008;375(5):1222-33.
2008: Adriano Aguzzi
Unraveling prion strains with cell biology and organic chemistry.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):11-2.
2008: Magdalini Polymenidou; Rita Moos; Mike Scott; Christina J Sigurdson; Yong-Zhong Shi; Bill Yajima; Iva Hafner Bratkovič; Roman Jerala; Simone Hornemann; Kurt Wuthrich; Anne Bellon; Martin Vey; Graciela Garen; Michael N G James; Nat Kav; Adriano Aguzzi
The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.
PloS one 2008;3(12):e3872.
2008: Gino Miele; Harald Seeger; Denis Marino; Ralf Eberhard; Mathias Heikenwalder; Katharina Stoeck; Max Basagni; Richard Knight; Alison Green; Francesca Chianini; Rudolf P Wüthrich; Christoph Hock; Inga Zerr; Adriano Aguzzi
Urinary alpha1-antichymotrypsin: a biomarker of prion infection.
PloS one 2008;3(12):e3870.
2008: Adriano Aguzzi; Frank Baumann; Juliane Bremer
The prion's elusive reason for being.
Annual review of neuroscience 2008;31():439-77.
2008: Jeppe Falsig; Adriano Aguzzi
The prion organotypic slice culture assay--POSCA.
Nature protocols 2008;3(4):555-62.
2008: Laura Debatin; Johannes R Streffer; Markus Geissen; Jakob Matschke; Adriano Aguzzi; Markus Glatzel
Association between deposition of beta-amyloid and pathological prion protein in sporadic Creutzfeldt-Jakob disease.
Neuro-degenerative diseases 2008;5(6):347-54.
2008: Adriano Aguzzi; Christina Sigurdson; Mathias Heikenwaelder
Molecular mechanisms of prion pathogenesis.
Annual review of pathology 2008;3():11-40.
2008: Jeppe Falsig; Christian Julius; Ilan Margalith; Petra Schwarz; Frank L Heppner; Adriano Aguzzi
A versatile prion replication assay in organotypic brain slices.
Nature neuroscience 2008;11(1):109-17.
2007: Christina J Sigurdson; K Peter R Nilsson; Simone Hornemann; Giuseppe Manco; Magdalini Polymenidou; Petra Schwarz; Mario Leclerc; Per Hammarström; Kurt Wüthrich; Adriano Aguzzi
Prion strain discrimination using luminescent conjugated polymers.
Nature methods 2007;4(12):1023-30.
2007: Mathias Heikenwalder; Christian Federau; Lotta von Boehmer; Petra Schwarz; Mareike Wagner; Nicolas Zeller; Johannes Haybaeck; Marco Prinz; Burkhard Becher; Adriano Aguzzi
Germinal center B cells are dispensable in prion transport and neuroinvasion.
Journal of neuroimmunology 2007;192(1-2):113-23.
2007: Mark D Zabel; Mathias Heikenwalder; Marco Prinz; Isabelle Arrighi; Petra Schwarz; Jan Kranich; Adriana von Teichman; Karen M Haas; Nicolas Zeller; Thomas F Tedder; John H Weis; Adriano Aguzzi
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6144-52.
2007: Giuseppe Marruchella; Ciriaco Ligios; Valeria Albanese; Maria Giovanna Cancedda; Laura Madau; Giovanna Lalatta-Costerbosa; Maurizio Mazzoni; Paolo Clavenzani; Roberto Chiocchetti; Giuseppe Sarli; Luigi De Grossi; Umberto Agrimi; Adriano Aguzzi; Giovanni Di Guardo
Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheep.
The Journal of general virology 2007;88(Pt 10):2899-904.
2007: Oriol Nicolas; Rosalina Gavín; Nathalie Braun; Jesús M Ureña; Xavier Fontana; Eduardo Soriano; Adriano Aguzzi; José A del Río
Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3107-17.
2007: Mathias Heikenwalder; Christian Julius; Adriano Aguzzi
Prions and peripheral nerves: a deadly rendezvous.
Journal of neuroscience research 2007;85(12):2714-25.
2007: Alejandra Rangel; Ferran Burgaya; Rosalina Gavín; Eduardo Soriano; Adriano Aguzzi; José A del Río
Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors.
Journal of neuroscience research 2007;85(12):2741-55.
2007: Adriano Aguzzi
Prion biology: the quest for the test.
Nature methods 2007;4(8):614-6.
2007: Adriano Aguzzi; Mathias Heikenwalder; Magdalini Polymenidou
Insights into prion strains and neurotoxicity.
Nature reviews. Molecular cell biology 2007;8(7):552-61.
2007: Christina J Sigurdson; Adriano Aguzzi
Chronic wasting disease.
Biochimica et biophysica acta 2007;1772(6):610-8.
2007: Andrew D Steele; Susan Lindquist; Adriano Aguzzi
The prion protein knockout mouse: a phenotype under challenge.
Prion 2007;1(2):83-93.
2007: Frank Baumann; Markus Tolnay; Christine Brabeck; Jens Pahnke; Ulrich Kloz; Hartmut H Niemann; Mathias Heikenwalder; Thomas Rülicke; Alexander Bürkle; Adriano Aguzzi
Lethal recessive myelin toxicity of prion protein lacking its central domain.
The EMBO journal 2007;26(2):538-47.
2006: Christina J Sigurdson; Giuseppe Manco; Petra Schwarz; Pawel P Liberski; Edward A Hoover; Simone Hornemann; Magdalini Polymenidou; Michael W Miller; Markus Glatzel; Adriano Aguzzi
Strain fidelity of chronic wasting disease upon murine adaptation.
Journal of virology 2006;80(24):12303-11.
2006: Josef Priller; Marco Prinz; Mathias Heikenwalder; Nicolas Zeller; Petra Schwarz; Frank L Heppner; Adriano Aguzzi
Early and rapid engraftment of bone marrow-derived microglia in scrapie.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(45):11753-62.
2006: Stefan Baenziger; Roxane Tussiwand; Erika Schlaepfer; Luca Mazzucchelli; Mathias Heikenwalder; Michael O Kurrer; Silvia Behnke; Joachim Frey; Annette Oxenius; Helen Joller; Adriano Aguzzi; Markus G Manz; Roberto F Speck
Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15951-6.
2006: Adriano Aguzzi; Mathias Heikenwalder
Pathogenesis of prion diseases: current status and future outlook.
Nature reviews. Microbiology 2006;4(10):765-75.
2006: Tobias Junt; Alexei Tumanov; Nicola Harris; Mathias Heikenwalder; Nicolas Zeller; Dmitry V Kuprash; Adriano Aguzzi; Burkhard Ludewig; Sergei A Nedospasov; Rolf M Zinkernagel
Expression of lymphotoxin beta governs immunity at two distinct levels.
European journal of immunology 2006;36(8):2061-75.
2006: Adriano Aguzzi; Markus Glatzel
Prion infections, blood and transfusions.
Nature clinical practice. Neurology 2006;2(6):321-9.
2006: Adriano Aguzzi
Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis.
Journal of neurochemistry 2006;97(6):1726-39.
2006: Hans-Peter Landolt; Markus Glatzel; Thomas Blättler; Peter Achermann; C Roth; Johannes Mathis; J Weis; Irene Tobler; Adriano Aguzzi; Claudio Bassetti
Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease.
Neurology 2006;66(9):1418-24.
2006: Silke Vogelgesang; Markus Glatzel; Lary Walker; Heyo K Kroemer; Adriano Aguzzi; Rolf Warzok
Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease.
Acta neuropathologica 2006;111(5):436-43.
2006: Gaby Schoch; Harald Seeger; daryoush heydari; Markus Tolnay; Robert Janzer; Adriano Aguzzi; Markus Glatzel
Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.
PLoS medicine 2006;3(2):e14.
2005: Magdalini Polymenidou; Katharina Stoeck; Markus Glatzel; Martin Vey; Anne Bellon; Adriano Aguzzi
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease.
Lancet neurology 2005;4(12):805-14.
2005: Ciriaco Ligios; Christina J Sigurdson; Cinzia Santucciu; Gabriella Carcassola; Giuseppe Manco; Massimo Basagni; Caterina Maestrale; Maria Giovanna Cancedda; Laura Madau; Adriano Aguzzi
PrPSc in mammary glands of sheep affected by scrapie and mastitis.
Nature medicine 2005;11(11):1137-8.
2005: Gabor Geza Kovacs; Maria Puopolo; Anna Ladogana; Maurizio Pocchiari; Herbert Budka; C.M. Duijn; Steven J Collins; Alison Boyd; Antonio Giulivi; Michael B Coulthart; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Inga Zerr; Hans A Kretzschmar; Jesús de Pedro-Cuesta; Miguel Calero-Lara; Markus Glatzel; Adriano Aguzzi; Matthew Bishop; Richard Knight; Girma Belay; Robert Will; Eva Mitrova
Genetic prion disease: the EUROCJD experience.
Human genetics 2005;118(2):166-74.
2005: Cristian Galvan; Paola G Camoletto; Carlos G Dotti; Adriano Aguzzi; Maria Dolores Ledesma
Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons.
Molecular and cellular neurosciences 2005;30(3):304-15.
2005: Harald Seeger; Mathias Heikenwalder; Nicolas Zeller; Jan Kranich; Petra Schwarz; Ariana Gaspert; Burkhardt Seifert; Gino Miele; Adriano Aguzzi
Coincident scrapie infection and nephritis lead to urinary prion excretion.
Science (New York, N.Y.) 2005;310(5746):324-6.
2005: Rosalina Gavín; Nathalie Braun; Oriol Nicolas; Beatriz Parra; Jesús M Ureña; Ana Mingorance; Eduardo Soriano; Juan M Torres; Adriano Aguzzi; José A del Río
PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc.
FEBS letters 2005;579(19):4099-106.
2005: Andreas Papassotiropoulos; M Axel Wollmer; Adriano Aguzzi; Christoph Hock; Roger M Nitsch; Dominique J-F de Quervain
The prion gene is associated with human long-term memory.
Human molecular genetics 2005;14(15):2241-6.
2005: Gaetano Donofrio; Frank L Heppner; Magdalini Polymenidou; Christine Huber-Musahl; Adriano Aguzzi
Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies.
Journal of virology 2005;79(13):8330-8.
2005: Adriano Aguzzi
Cell biology. Prion toxicity: all sail and no anchor.
Science (New York, N.Y.) 2005;308(5727):1420-1.
2005: Markus Glatzel; M Hasan Mohajeri; Raphael Poirier; Roger M Nitsch; Petra Schwarz; Bao Lu; Adriano Aguzzi
No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis.
The Journal of general virology 2005;86(Pt 6):1861-7.
2005: Ivan Radovanovic; Nathalie Braun; Olivier T Giger; Kirsten Mertz; Gino Miele; Marco Prinz; Beatriz Navarro; Adriano Aguzzi
Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPC.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(19):4879-88.
2005: Anna Ladogana; Maria Puopolo; Esther Croes; Herbert Budka; Christa Jarius; Steven Collins; Genevieve M Klug; T Sutcliffe; Antonio Giulivi; A Alperovitch; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Sigrid Poser; Hans A Kretzschmar; I Rietveld; Eva Mitrova; J de Pedro Cuesta; P Martinez-Martin; Markus Glatzel; Adriano Aguzzi; Richard Knight; H Ward; Maurizio Pocchiari; C.M. Duijn; Robert G Will; Inga Zerr
Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada.
Neurology 2005;64(9):1586-91.
2005: Christoph Huber; Caroline Thielen; Harald Seeger; Petra Schwarz; Fabio Montrasio; Mark R Wilson; Ernst Heinen; Yang-Xin Fu; Gino Miele; Adriano Aguzzi
Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5526-36.
2005: Pierre-Olivier Frappart; Wei-Min Tong; Ilja Demuth; Ivan Radovanovic; Zdenko Herceg; Adriano Aguzzi; Martin Digweed; Zhao-Qi Wang
An essential function for NBS1 in the prevention of ataxia and cerebellar defects.
Nature medicine 2005;11(5):538-44.
2005: Markus Glatzel; Katharina Stoeck; Harald Seeger; Thorsten Lührs; Adriano Aguzzi
Human prion diseases: molecular and clinical aspects.
Archives of neurology 2005;62(4):545-52.
2005: Daphne Nikles; Patricia Bach; Klaus Boller; Christoph A Merten; Fabio Montrasio; Frank L Heppner; Adriano Aguzzi; Klaus Cichutek; Ulrich Kalinke; Christian J Buchholz
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.
Journal of virology 2005;79(7):4033-42.
2005: Heike Russmann; François Vingerhoets; Judith Miklossy; Philippe Maeder; Markus Glatzel; Adriano Aguzzi; daryoush heydari
Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging.
Journal of neurology 2005;252(3):338-42.
2005: Mathias Heikenwalder; Nicolas Zeller; Harald Seeger; Marco Prinz; Peter-Christian Klöhn; Petra Schwarz; Nancy H Ruddle; Charles Weissmann; Adriano Aguzzi
Chronic lymphocytic inflammation specifies the organ tropism of prions.
Science (New York, N.Y.) 2005;307(5712):1107-10.
2005: Armgard Uelhoff; Jörg Tatzelt; Adriano Aguzzi; Konstanze F Winklhofer; Christian Haass
A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.
The Journal of biological chemistry 2005;280(7):5137-40.
2005: Joanna Masel; Nicolas Genoud; Adriano Aguzzi
Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer.
Journal of molecular biology 2005;345(5):1243-51.
2005: Adriano Aguzzi; Mathias Heikenwalder
Prions, cytokines, and chemokines: a meeting in lymphoid organs.
Immunity 2005;22(2):145-54.
2005: Petra Steinacker; Petra Schwarz; Kerstin Reim; Peter Brechlin; Olaf Jahn; Hartmut Kratzin; Alastair Aitken; Jens Wiltfang; Adriano Aguzzi; Erik Bahn; Helen C Baxter; Nils Brose; Markus Otto
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein.
Molecular and cellular biology 2005;25(4):1339-46.
2005: Frank L Heppner; Melanie Greter; Denis Marino; Jeppe Falsig; Gennadij Raivich; Nadine Hövelmeyer; Ari Waisman; Thomas Rülicke; Marco Prinz; Josef Priller; Burkhard Becher; Adriano Aguzzi
Experimental autoimmune encephalomyelitis repressed by microglial paralysis.
Nature medicine 2005;11(2):146-52.
2005: Christina J Sigurdson; Magdalini Polymenidou; Adriano Aguzzi
Reconstructing prions: fibril assembly from simple yeast to complex mammals.
Neuro-degenerative diseases 2005;2(1):1-5.
2005: Charles Weissmann; Adriano Aguzzi
Approaches to therapy of prion diseases.
Annual review of medicine 2005;56():321-44.
2005: Christina J Sigurdson; Markus Glatzel; Adriano Aguzzi
Comment on "Failure to detect prion protein (PrPres) by immunohistochemistry in striated muscle tissues of animals experimentally inoculated with agents of transmissible spongiform encephalopathy".
Veterinary pathology 2005;42(1):107.
2004: Nicolas Spaeth; Matthias T Wyss; Bruno Weber; Stephan Scheidegger; Amelie M Lutz; Jorn Verwey; Ivan Radovanovic; Jens Pahnke; Damian Wild; Gerrit Westera; Dominik Weishaupt; Dirk M Hermann; Barbara Kaser-Hotz; Adriano Aguzzi; Alfred Buck
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(11):1931-8.
2004: Magdalini Polymenidou; Frank L Heppner; Erica C Pellicioli; Eduard Urich; Gino Miele; Nathalie Braun; Franziska Wopfner; Hermann M Schätzl; Burkhard Becher; Adriano Aguzzi
Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14670-6.
2004: Maurizio Pocchiari; Maria Puopolo; Esther Croes; Herbert Budka; Ellen Gelpi; Steven Collins; V Lewis; T Sutcliffe; A Guilivi; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; A Alperovitch; Inga Zerr; Sigrid Poser; Hans A Kretzschmar; Anna Ladogana; I Rietvald; Eva Mitrova; P Martinez-Martin; Jesús de Pedro-Cuesta; Markus Glatzel; Adriano Aguzzi; S Cooper; J Mackenzie; C.M. Duijn; Robert G Will
Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.
Brain : a journal of neurology 2004;127(Pt 10):2348-59.
2004: Frank L Heppner; Adriano Aguzzi
Recent developments in prion immunotherapy.
Current opinion in immunology 2004;16(5):594-8.
2004: Adriano Aguzzi; Christina J Sigurdson
Antiprion immunotherapy: to suppress or to stimulate?
Nature reviews. Immunology 2004;4(9):725-36.
2004: Adriano Aguzzi
Host-microbe interactions: viruses a never-ending creativity contest.
Current opinion in microbiology 2004;7(4):397-9.
2004: Gennadij Raivich; Marion Bohatschek; Clive Da Costa; Osuke Iwata; Matthias Galiano; Mariya Hristova; Abdolrahman S Nateri; Milan Makwana; Lluís Riera-Sans; David P Wolfer; Hans-Peter Lipp; Adriano Aguzzi; Erwin F Wagner; Axel Behrens
The AP-1 transcription factor c-Jun is required for efficient axonal regeneration.
Neuron 2004;43(1):57-67.
2004: Adriano Aguzzi; Mathias Heikenwalder; Gino Miele
Progress and problems in the biology, diagnostics, and therapeutics of prion diseases.
The Journal of clinical investigation 2004;114(2):153-60.
2004: Marco Prinz; Fabio Montrasio; Hisako Furukawa; Marjan E van der Haar; Petra Schwarz; Thomas Rülicke; Olivier T Giger; Karl-Georg Häusler; Daniel Perez; Markus Glatzel; Adriano Aguzzi
Intrinsic resistance of oligodendrocytes to prion infection.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(26):5974-81.
2004: Markus Glatzel; Olivier T Giger; Nathalie Braun; Adriano Aguzzi
The peripheral nervous system and the pathogenesis of prion diseases.
Current molecular medicine 2004;4(4):355-9.
2004: Adriano Aguzzi; Gino Miele
Recent advances in prion biology.
Current opinion in neurology 2004;17(3):337-42.
2004: Jakob Weissenberger; Sébastien Loeffler; Andreas Kappeler; Manfred Kopf; Anton Lukes; Tatiana A Afanasieva; Adriano Aguzzi; Joachim Weis
IL-6 is required for glioma development in a mouse model.
Oncogene 2004;23(19):3308-16.
2004: Adriano Aguzzi
Understanding the diversity of prions.
Nature cell biology 2004;6(4):290-2.
2004: Nicolas Genoud; Axel Behrens; Gino Miele; Dimitri Robay; Frank L Heppner; Stefan Freigang; Adriano Aguzzi
Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4198-203.
2004: andrea rossetti; daryoush heydari; Markus Glatzel; Adriano Aguzzi
Mimicry of variant Creutzfeldt-Jakob disease by sporadic Creutzfeldt-Jakob disease: importance of the pulvinar sign.
Archives of neurology 2004;61(3):445-6.
2004: Adriano Aguzzi; Markus Glatzel
vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?
Lancet 2004;363(9407):411-2.
2004: Markus Glatzel; Olivier T Giger; Harald Seeger; Adriano Aguzzi
Variant Creutzfeldt-jakob disease: between lymphoid organs and brain.
Trends in microbiology 2004;12(2):51-3.
2004: Sam Gandy; Ron B DeMattos; Cynthia A Lemere; Frank L Heppner; Jodi Leverone; Adriano Aguzzi; William B. Ershler; Jinlu Dai; Paul E Fraser; Peter St George-Hyslop; David M Holtzman; Lary Walker; Evan T Keller
Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta).
Mechanisms of ageing and development 2004;125(2):149-51.
2004: Mathias Heikenwalder; Magdalini Polymenidou; Tobias Junt; Christina J Sigurdson; Hermann Wagner; Shizuo Akira; Rolf M Zinkernagel; Adriano Aguzzi
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration.
Nature medicine 2004;10(2):187-92.
2004: Adriano Aguzzi; Magdalini Polymenidou
Mammalian prion biology: one century of evolving concepts.
Cell 2004;116(2):313-27.
2004: Sam Gandy; Ron B DeMattos; Cynthia A Lemere; Frank L Heppner; Jodi Leverone; Adriano Aguzzi; William B. Ershler; Jinlu Dai; Paul E Fraser; Peter St George-Hyslop; David M Holtzman; Lary Walker; Evan T Keller
Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta).
Alzheimer disease and associated disorders 2004;18(1):44-6.
2004: Mathias Heikenwalder; Marco Prinz; Frank L Heppner; Adriano Aguzzi
Current concepts and controversies in prion immunopathology.
Journal of molecular neuroscience : MN 2004;23(1-2):3-12.
2004: Ivan Radovanovic; Maria G D'Angelo; Adriano Aguzzi
Angiogenesis in transgenic models of multistep angiogenesis.
Cancer treatment and research 2004;117():97-114.
2004: Gabor Geza Kovacs; Elisabeth Lindeck-Pozza; Leila Chimelli; A Q C Araújo; Alberto A Gabbai; Thomas Ströbel; Markus Glatzel; Adriano Aguzzi; Herbert Budka
Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle.
Annals of neurology 2004;55(1):121-5.
2003: Markus Glatzel; Peter M Ott; Thomas Linder; Jan O Gebbers; Arnold Gmür; Werner Wüst; Gerhard Huber; Holger Moch; Michael Podvinec; Bernhard Stamm; Adriano Aguzzi
Human prion diseases: epidemiology and integrated risk assessment.
Lancet neurology 2003;2(12):757-63.
2003: Markus Glatzel; Eugenio Abela; Manuela Maissen; Adriano Aguzzi
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease.
The New England journal of medicine 2003;349(19):1812-20.
2003: Adriano Aguzzi; Christian Haass
Games played by rogue proteins in prion disorders and Alzheimer's disease.
Science (New York, N.Y.) 2003;302(5646):814-8.
2003: Marco Prinz; Mathias Heikenwalder; Tobias Junt; Petra Schwarz; Markus Glatzel; Frank L Heppner; Yang-Xin Fu; Martin Lipp; Adriano Aguzzi
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion.
Nature 2003;425(6961):957-62.
2003: Gregor Hutter; Frank L Heppner; Adriano Aguzzi
No superoxide dismutase activity of cellular prion protein in vivo.
Biological chemistry 2003;384(9):1279-85.
2003: Adriano Aguzzi; Wolf-Dietrich Hardt
Dangerous liaisons between a microbe and the prion protein.
The Journal of experimental medicine 2003;198(1):1-4.
2003: Eckhard Flechsig; Ivan Hegyi; Rainer Leimeroth; Armando Zuniga; Daniela Rossi; Antonio Cozzio; Petra Schwarz; Thomas Rülicke; Jürgen Götz; Adriano Aguzzi; Charles Weissmann
Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.
The EMBO journal 2003;22(12):3095-101.
2003: J B Lampe; S Schneider-Schaulies; Adriano Aguzzi
Expression of the interferon-induced MxA protein in viral encephalitis.
Neuropathology and applied neurobiology 2003;29(3):273-9.
2003: Adriano Aguzzi; Mathias Heikenwalder
Prion diseases: Cannibals and garbage piles.
Nature 2003;423(6936):127-9.
2003: Philippe Bertolino; Ivan Radovanovic; Huguette Casse; Adriano Aguzzi; Zhao-Qi Wang; Chang X Zhang
Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.
Mechanisms of development 2003;120(5):549-60.
2003: Michael Praus; Gerhard Kettelgerdes; Michael Baier; Hermann-Georg Holzhütter; Peter Jungblut; Manuela Maissen; Guido Epple; Wolf-Dieter Schleuning; Eckart Köttgen; Adriano Aguzzi; Reinhard Gessner
Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110.
Thrombosis and haemostasis 2003;89(5):812-9.
2003: Philipp Meier; Nicolas Genoud; Marco Prinz; Manuela Maissen; Thomas Rülicke; Andreas Zurbriggen; Alex J Raeber; Adriano Aguzzi
Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease.
Cell 2003;113(1):49-60.
2003: andrea rossetti; Markus Glatzel; Adriano Aguzzi; Robert Janzer; daryoush heydari
Clinical and radiological mimicry of vCJD in a valine homozygous PrP(Sc) type 1 sCJD patient.
Journal of neurology 2003;250(4):491-3.
2003: Marco Prinz; Gerhard Huber; Andrew J S Macpherson; Frank L Heppner; Markus Glatzel; Hans-Pietro Eugster; Norbert Wagner; Adriano Aguzzi
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes.
The American journal of pathology 2003;162(4):1103-11.
2003: Marco Prinz; Mathias Heikenwalder; Petra Schwarz; Kiyoshi Takeda; Shizuo Akira; Adriano Aguzzi
Prion pathogenesis in the absence of Toll-like receptor signalling.
EMBO reports 2003;4(2):195-9.
2003: Nicolas Genoud; Axel Behrens; I Arrighi; Adriano Aguzzi
Prion proteins and infertility: insight from mouse models.
Cytogenetic and genome research 2003;103(3-4):285-9.
2003: Adriano Aguzzi
Prions and the immune system: a journey through gut, spleen, and nerves.
Advances in immunology 2003;81():123-71.
2003: Adriano Aguzzi; Frank L Heppner; Mathias Heikenwalder; Marco Prinz; Kirsten Mertz; Harald Seeger; Markus Glatzel
Immune system and peripheral nerves in propagation of prions to CNS.
British medical bulletin 2003;66():141-59.
2002: Markus Glatzel; J Gottwein; Adriano Aguzzi
[Prions as the driving force in transmissible spongiform encephalopathies].
Schweizer Archiv für Tierheilkunde 2002;144(12):633-8.
2002: Valerie Künzi; Markus Glatzel; Michel Y Nakano; Urs F Greber; Fred Van Leuven; Adriano Aguzzi
Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(17):7471-7.
2002: Axel Behrens; Nicolas Genoud; Heike Naumann; Thomas Rülicke; Fredi Janett; Frank L Heppner; Birgit Ledermann; Adriano Aguzzi
Absence of the prion protein homologue Doppel causes male sterility.
The EMBO journal 2002;21(14):3652-8.
2002: Markus Glatzel; Colette Rogivue; Azra Ghani; Johannes R Streffer; Lorenz Amsler; Adriano Aguzzi
Incidence of Creutzfeldt-Jakob disease in Switzerland.
Lancet 2002;360(9327):139-41.
2002: Markus Glatzel; Vladimir Pekarik; Thorsten Lührs; John Dittami; Adriano Aguzzi
Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F).
Biological chemistry 2002;383(6):1021-5.
2002: S Sisó; B Puig; R Varea; Enric Vidal; C Acín; Marco Prinz; Fabio Montrasio; Juan José Badiola; Adriano Aguzzi; Martí Pumarola; Isidro Ferrer
Abnormal synaptic protein expression and cell death in murine scrapie.
Acta neuropathologica 2002;103(6):615-26.
2002: Jörg Wischhusen; Gundram Jung; Ivan Radovanovic; Christoph P Beier; Joachim P Steinbach; Andreas Rimner; Huatao Huang; Jörg B Schulz; Hiroko Ohgaki; Adriano Aguzzi; Hans-Georg Rammensee; Michael Weller
Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma.
Cancer research 2002;62(9):2592-9.
2002: Adriano Aguzzi
[The prion hypothesis and the human prion diseases].
Berliner und Münchener tierärztliche Wochenschrift 2002;115(3-4):91-8.
2002: Axel Behrens; Adriano Aguzzi
Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.
Trends in neurosciences 2002;25(3):150-4.
2002: Alana M Thackray; Michael A Klein; Adriano Aguzzi; Raymond Bujdoso
Chronic subclinical prion disease induced by low-dose inoculum.
Journal of virology 2002;76(5):2510-7.
2002: F L Heppner; Adriano Aguzzi
[Immunity against prions?].
Deutsche medizinische Wochenschrift (1946) 2002;127(7):328-30.
2002: Markus Glatzel; Sebastian Brandner; Michael A Klein; Sonja Horstmann; Adriano Aguzzi
Prions--role of the peripheral nervous system.
Virus research 2002;82(1-2):53.
2002: Marco Prinz; Fabio Montrasio; Michael A Klein; Petra Schwarz; Josef Priller; Bernhard Odermatt; Klaus Pfeffer; Adriano Aguzzi
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):919-24.
2002: Kurt Zatloukal; Conny Stumptner; Andrea Fuchsbichler; Hans Heid; Martina Schnoelzer; Lukas Kenner; Reinhold Kleinert; Marco Prinz; Adriano Aguzzi; Helmut Denk
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases.
The American journal of pathology 2002;160(1):255-63.
2001: P Parizek; C Roeckl; J Weber; Eckhard Flechsig; Adriano Aguzzi; Alex J Raeber
Similar turnover and shedding of the cellular prion protein in primary lymphoid and neuronal cells.
The Journal of biological chemistry 2001;276(48):44627-32.
2001: Thomas Birchler; Reinhart Seibl; K Büchner; Susanne Loeliger; Reinhard Seger; Johann Peter Hossle; Adriano Aguzzi; Roger Lauener
Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein.
European journal of immunology 2001;31(11):3131-7.
2001: Markus Glatzel; Adriano Aguzzi
Sympathetic prions.
TheScientificWorldJournal 2001;1():555-6.
2001: Frank L Heppner; Christine Huber-Musahl; I Arrighi; Michael A Klein; Thomas Rülicke; Bruno Oesch; Rolf M Zinkernagel; Ulrich Kalinke; Adriano Aguzzi
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.
Science (New York, N.Y.) 2001;294(5540):178-82.
2001: Markus Glatzel; Adriano Aguzzi
The shifting biology of prions.
Brain research. Brain research reviews 2001;36(2-3):241-8.
2001: Adriano Aguzzi; Markus Glatzel; Fabio Montrasio; Marco Prinz; Frank L Heppner
Interventional strategies against prion diseases.
Nature reviews. Neuroscience 2001;2(10):745-9.
2001: Adriano Aguzzi
Peripheral prion pursuit.
The Journal of clinical investigation 2001;108(5):661-2.
2001: Joachim P Steinbach; Zbynek Kozmik; P Pfeffer; Adriano Aguzzi
Overexpression of Pax5 is not sufficient for neoplastic transformation of mouse neuroectoderm.
International journal of cancer. Journal international du cancer 2001;93(4):459-67.
2001: PS Kaeser; Michael A Klein; Petra Schwarz; Adriano Aguzzi
Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.
Journal of virology 2001;75(15):7097-106.
2001: Markus Glatzel; Frank L Heppner; K M Albers; Adriano Aguzzi
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion.
Neuron 2001;31(1):25-34.
2001: Manuela Maissen; C Roeckl; Markus Glatzel; Wilfred Goldmann; Adriano Aguzzi
Plasminogen binds to disease-associated prion protein of multiple species.
Lancet 2001;357(9273):2026-8.
2001: Johannes A Hainfellner; Till Voigtländer; Thomas Ströbel; Peter R Mazal; AS Maddalena; Adriano Aguzzi; Herbert Budka
Fibroblasts can express glial fibrillary acidic protein (GFAP) in vivo.
Journal of neuropathology and experimental neurology 2001;60(5):449-61.
2001: T A Afanasieva; Vladimir Pekarik; M Grazia D'Angelo; Michael A Klein; T Voigtländer; C Stocking; Adriano Aguzzi
Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus.
Journal of neurovirology 2001;7(2):169-81.
2001: Axel Behrens; Sebastian Brandner; Nicolas Genoud; Adriano Aguzzi
Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel.
EMBO reports 2001;2(4):347-52.
2001: Michael A Klein; PS Kaeser; Petra Schwarz; H Weyd; I Xenarios; Rolf M Zinkernagel; M C Carroll; Sjef Verbeek; M Botto; M J Walport; H Molina; Ulrich Kalinke; H Acha-Orbea; Adriano Aguzzi
Complement facilitates early prion pathogenesis.
Nature medicine 2001;7(4):488-92.
2001: Fabio Montrasio; Antonio Cozzio; Eckhard Flechsig; Daniela Rossi; Michael A Klein; Thomas Rülicke; Alex J Raeber; C A Vosshenrich; J Proft; Adriano Aguzzi; Charles Weissmann
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4034-7.
2001: Charles Weissmann; Alex J Raeber; Fabio Montrasio; Ivan Hegyi; Rico Frigg; Michael A Klein; Adriano Aguzzi
Prions and the lymphoreticular system.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1406):177-84.
2001: Daniela Rossi; Antonio Cozzio; Eckhard Flechsig; Michael A Klein; Thomas Rülicke; Adriano Aguzzi; Charles Weissmann
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain.
The EMBO journal 2001;20(4):694-702.
2001: Adriano Aguzzi; Fabio Montrasio; PS Kaeser
Prions: health scare and biological challenge.
Nature reviews. Molecular cell biology 2001;2(2):118-26.
2001: Alex J Raeber; Fabio Montrasio; Ivan Hegyi; Rico Frigg; Michael A Klein; Adriano Aguzzi; Charles Weissmann
Studies on prion replication in spleen.
Developmental immunology 2001;8(3-4):291-304.
2001: Frank L Heppner; Marco Prinz; Adriano Aguzzi
Pathogenesis of prion diseases: possible implications of microglial cells.
Progress in brain research 2001;132():737-50.
2001: Adriano Aguzzi; Sebastian Brandner; MB Fischer; Hisako Furukawa; Markus Glatzel; C Hawkins; Frank L Heppner; Fabio Montrasio; Beatriz Navarro; P Parizek; Vladimir Pekarik; Marco Prinz; Alex J Raeber; C Röckl; Michael A Klein
Spongiform encephalopathies: insights from transgenic models.
Advances in virus research 2001;56():313-52.
2000: MB Fischer; C Roeckl; P Parizek; H P Schwarz; Adriano Aguzzi
Binding of disease-associated prion protein to plasminogen.
Nature 2000;408(6811):479-83.
2000: M A Klein; D Rüedi; Michimasa Nozaki; E W Dell; Annie-Claire Diserens; W Seelentag; Robert Janzer; Adriano Aguzzi; Monika E Hegi
Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant.
Oncogene 2000;19(47):5329-37.
2000: Sebastian Brandner; Michael A Klein; Rico Frigg; Vladimir Pekarik; P Parizek; Alex J Raeber; Markus Glatzel; Petra Schwarz; Thomas Rülicke; Charles Weissmann; Adriano Aguzzi
Neuroinvasion of prions: insights from mouse models.
Experimental physiology 2000;85(6):705-12.
2000: Markus Glatzel; Adriano Aguzzi
PrP(C) expression in the peripheral nervous system is a determinant of prion neuroinvasion.
The Journal of general virology 2000;81(Pt 11):2813-21.
2000: Adriano Aguzzi; Frank L Heppner
Pathogenesis of prion diseases: a progress report.
Cell death and differentiation 2000;7(10):889-902.
2000: M G D' Angelo; T Afanasieva; Adriano Aguzzi
Angiogenesis in transgenic models of multistep carcinogenesis.
Journal of neuro-oncology 2000;50(1-2):89-98.
2000: Eckhard Flechsig; David H Shmerling; Ivan Hegyi; Alex J Raeber; Marc Fischer; Antonio Cozzio; C von Mering; Adriano Aguzzi; Charles Weissmann
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.
Neuron 2000;27(2):399-408.
2000: Y Benninger; S Marino; R Hardegger; Charles Weissmann; Adriano Aguzzi; Sebastian Brandner
Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice.
Brain pathology (Zurich, Switzerland) 2000;10(3):330-41.
2000: G Politopoulou; J D Seebach; M Schmugge; H P Schwarz; Adriano Aguzzi
Age-related expression of the cellular prion protein in human peripheral blood leukocytes.
Haematologica 2000;85(6):580-7.
2000: Monika E Hegi; M A Klein; D Rüedi; P Chène; Marie-France Hamou; Adriano Aguzzi
p53 transdominance but no gain of function in mouse brain tumor model.
Cancer research 2000;60(11):3019-24.
2000: Fabio Montrasio; Rico Frigg; Markus Glatzel; Michael A Klein; F Mackay; Adriano Aguzzi; Charles Weissmann
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells.
Science (New York, N.Y.) 2000;288(5469):1257-9.
2000: Markus Glatzel; Adriano Aguzzi
Peripheral pathogenesis of prion diseases.
Microbes and infection / Institut Pasteur 2000;2(6):613-9.
2000: Sebastian Brandner; Michael A Klein; Adriano Aguzzi
[Mechanisms of neuroinvasion by prions: molecular principles and present state of research].
Schweizerische medizinische Wochenschrift 2000;130(12):435-42.
2000: Alex J Raeber; Adriano Aguzzi
Engulfment of prions in the germinal centre.
Immunology today 2000;21(2):66-7.
2000: Markus Glatzel; Eckhard Flechsig; Beatriz Navarro; Michael A Klein; Jean-Charles Paterna; Hansruedi Büeler; Adriano Aguzzi
Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):442-7.
2000: Markus Glatzel; Michael A Klein; Sebastian Brandner; Adriano Aguzzi
Prions: from neurografts to neuroinvasion.
Archives of virology. Supplementum 2000;(16):3-12.
2000: Adriano Aguzzi; Michael A Klein; Fabio Montrasio; Vladimir Pekarik; Sebastian Brandner; Hisako Furukawa; P Käser; C Röckl; Markus Glatzel
Prions: pathogenesis and reverse genetics.
Annals of the New York Academy of Sciences 2000;920():140-57.
2000: Adriano Aguzzi
Molecular pathology of prion diseases.
Vox sanguinis 2000;78 Suppl 2():25.
2000: Adriano Aguzzi
Prion diseases, blood and the immune system: concerns and reality.
Haematologica 2000;85(1):3-10.
1999: Joachim P Steinbach; J Weissenberger; Adriano Aguzzi
Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice.
Neuropathology and applied neurobiology 1999;25(6):468-80.
1999: Rico Frigg; Michael A Klein; Ivan Hegyi; Rolf M Zinkernagel; Adriano Aguzzi
Scrapie pathogenesis in subclinically infected B-cell-deficient mice.
Journal of virology 1999;73(11):9584-8.
1999: Charles Weissmann; Adriano Aguzzi
Perspectives: neurobiology. PrP's double causes trouble.
Science (New York, N.Y.) 1999;286(5441):914-5.
1999: AS Maddalena; Johannes A Hainfellner; Monika E Hegi; Markus Glatzel; Adriano Aguzzi
No complementation between TP53 or RB-1 and v-src in astrocytomas of GFAP-v-src transgenic mice.
Brain pathology (Zurich, Switzerland) 1999;9(4):627-37.
1999: U Pohl; Wolfgang Wick; J Weissenberger; Joachim P Steinbach; Johannes Dichgans; Adriano Aguzzi; Michael Weller
Characterization of Tu-2449, a glioma cell line derived from a spontaneous tumor in GFAP-v-src-transgenic mice: comparison with established murine glioma cell lines.
International journal of oncology 1999;15(4):829-34.
1999: Hans Peter Hefti; Michael Frese; H Landis; C Di Paolo; Adriano Aguzzi; Otto Haller; Jovan Pavlovic
Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infections.
Journal of virology 1999;73(8):6984-91.
1999: Adriano Aguzzi; Sebastian Brandner
The genetics of prions--a contradiction in terms?
Lancet 1999;354 Suppl 1():SI22-5.
1999: Peter Lichtlen; Oleg Georgiev; Walter Schaffner; Adriano Aguzzi; Sebastian Brandner
The heavy metal-responsive transcription factor-1 (MTF-1) is not required for neural differentiation.
Biological chemistry 1999;380(6):711-5.
1999: Alex J Raeber; Michael A Klein; Rico Frigg; Eckhard Flechsig; Adriano Aguzzi; Charles Weissmann
PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice.
The EMBO journal 1999;18(10):2702-6.
1999: Alex J Raeber; A Sailer; Ivan Hegyi; Michael A Klein; Thomas Rülicke; Marc Fischer; Sebastian Brandner; Adriano Aguzzi; Charles Weissmann
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3987-92.
1999: Sebastian Brandner; Michael A Klein; Adriano Aguzzi
A crucial role for B cells in neuroinvasive scrapie.
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 1999;6(1):17-23.
1999: J P Theurillat; Johannes A Hainfellner; AS Maddalena; J Weissenberger; Adriano Aguzzi
Early induction of angiogenetic signals in gliomas of GFAP-v-src transgenic mice.
The American journal of pathology 1999;154(2):581-90.
1998: Adriano Aguzzi; M G D'Angelo; Michael A Klein; Rico Frigg; MB Fischer; Alex J Raeber; C Röckl; Christine Huber-Musahl; Ivan Hegyi; Sebastian Brandner
[The new research frontier on prion disease].
Pathologica 1998;90(6):743-52.
1998: Michael A Klein; Rico Frigg; Alex J Raeber; Eckhard Flechsig; Ivan Hegyi; Rolf M Zinkernagel; Charles Weissmann; Adriano Aguzzi
PrP expression in B lymphocytes is not required for prion neuroinvasion.
Nature medicine 1998;4(12):1429-33.
1998: Adriano Aguzzi
Grafting mouse brains: from neurocarcinogenesis to neurodegeneration.
The EMBO journal 1998;17(21):6107-14.
1998: Joachim P Steinbach; U Müller; M Leist; Z W Li; P Nicotera; Adriano Aguzzi
Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice.
Cell death and differentiation 1998;5(10):858-66.
1998: Alex J Raeber; Sebastian Brandner; Michael A Klein; Y Benninger; Christine Huber-Musahl; Rico Frigg; C Roeckl; MB Fischer; Charles Weissmann; Adriano Aguzzi
Transgenic and knockout mice in research on prion diseases.
Brain pathology (Zurich, Switzerland) 1998;8(4):715-33.
1998: Adriano Aguzzi; Alex J Raeber
Transgenic models of neurodegeneration. Neurodegeneration: of (transgenic) mice and men.
Brain pathology (Zurich, Switzerland) 1998;8(4):695-7.
1998: B Mrkic; Jovan Pavlovic; Thomas Rülicke; P Volpe; Christian J Buchholz; Dennis E Hourcade; John P Atkinson; Adriano Aguzzi; Roberto Cattaneo
Measles virus spread and pathogenesis in genetically modified mice.
Journal of virology 1998;72(9):7420-7.
1998: Gianluigi Zanusso; D Liu; S Ferrari; I Hegyi; X Yin; Adriano Aguzzi; Simone Hornemann; S Liemann; Rudi Glockshuber; Jean C Manson; P Brown; Robert B Petersen; Pierluigi Gambetti; Man-Sun Sy
Prion protein expression in different species: analysis with a panel of new mAbs.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8812-6.
1998: T Cathomen; B Mrkic; Danièle Spehner; Robert Drillien; R Naef; Jovan Pavlovic; Adriano Aguzzi; Martin A Billeter; Roberto Cattaneo
A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.
The EMBO journal 1998;17(14):3899-908.
1998: Adriano Aguzzi; Charles Weissmann
Prion diseases.
Haemophilia : the official journal of the World Federation of Hemophilia 1998;4(4):619-27.
1998: Cagatay Günes; R Heuchel; Oleg Georgiev; K H Müller; Peter Lichtlen; H Blüthmann; Silvia Marino; Adriano Aguzzi; Walter Schaffner
Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.
The EMBO journal 1998;17(10):2846-54.
1998: David H Shmerling; Ivan Hegyi; Marc Fischer; Thomas Blättler; Sebastian Brandner; Jürgen Götz; Thomas Rülicke; Eckhard Flechsig; Antonio Cozzio; C von Mering; C Hangartner; Adriano Aguzzi; Charles Weissmann
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.
Cell 1998;93(2):203-14.
1998: Charles Weissmann; Marc Fischer; Alex J Raeber; Hansruedi Büeler; A Sailer; David H Shmerling; Thomas Rülicke; Sebastian Brandner; Adriano Aguzzi
The use of transgenic mice in the investigation of transmissible spongiform encephalopathies.
Revue scientifique et technique (International Office of Epizootics) 1998;17(1):278-90.
1998: Ugo Rovigatti; T Afanasyeva; Sebastian Brandner; Johannes A Hainfellner; M Kiess; AS Maddalena; G Malin; Thomas Rülicke; J Steinbach; J Weissenberger; Adriano Aguzzi
Transgenic mice as research tools in neurocarcinogenesis.
Journal of neurovirology 1998;4(2):159-74.
1998: J Lampe; S Marino; A Rethwilm; Adriano Aguzzi
Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus.
Neuropathology and applied neurobiology 1998;24(1):36-43.
1998: Adriano Aguzzi; Michael A Klein; Christine Huber-Musahl; Alex J Raeber; Thomas Blättler; Ivan Hegyi; Rico Frigg; Sebastian Brandner
Use of brain grafts to study the pathogenesis of prion diseases.
Essays in biochemistry 1998;33():133-47.
1998: Alex J Raeber; Michael A Klein; Rico Frigg; Sebastian Brandner; Thomas Blättler; Adriano Aguzzi
[Significance of prion protein in transmission of prions and in pathogenesis of spongiform encephalopathies].
Wiener medizinische Wochenschrift (1946) 1998;148(4):74-7.
1998: Sebastian Brandner; S Isenmann; G Kühne; Adriano Aguzzi
Identification of the end stage of scrapie using infected neural grafts.
Brain pathology (Zurich, Switzerland) 1998;8(1):19-27.
1997: Michael A Klein; Rico Frigg; Eckhard Flechsig; Alex J Raeber; Ulrich Kalinke; Horst Bluethmann; F Bootz; M Suter; Rolf M Zinkernagel; Adriano Aguzzi
A crucial role for B cells in neuroinvasive scrapie.
Nature 1997;390(6661):687-90.
1997: Alex J Raeber; Richard E Race; Sebastian Brandner; Suzette A Priola; A Sailer; RA Bessen; Lennart Mucke; J Manson; Adriano Aguzzi; M B Oldstone; Charles Weissmann; Bruce Chesebro
Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.
The EMBO journal 1997;16(20):6057-65.
1997: Adriano Aguzzi; AS Maddalena; Sebastian Brandner; M Klein
[Molecular pathogenesis of spongiform encephalopathy].
Pathologica 1997;89(5):481-90.
1997: Charles Weissmann; Adriano Aguzzi
Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease.
Current opinion in neurobiology 1997;7(5):695-700.
1997: Thomas Blättler; Sebastian Brandner; Alex J Raeber; Michael A Klein; T Voigtländer; Charles Weissmann; Adriano Aguzzi
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain.
Nature 1997;389(6646):69-73.
1997: Paul D Bieniasz; Otto Erlwein; Adriano Aguzzi; Axel Rethwilm; Myra O McClure
Gene transfer using replication-defective human foamy virus vectors.
Virology 1997;235(1):65-72.
1997: Adriano Aguzzi; Thomas Blättler; Michael A Klein; A J Räber; Ivan Hegyi; Rico Frigg; Sebastian Brandner; Charles Weissmann
Tracking prions: the neurografting approach.
Cellular and molecular life sciences : CMLS 1997;53(6):485-95.
1997: Adriano Aguzzi; Alex J Raeber; Thomas Blättler; Eckhard Flechsig; M Klein; Charles Weissmann; Sebastian Brandner
Neurotoxicity and neuroinvasiveness of prions.
Journal of neurovirology 1997;3 Suppl 1():S23-4.
1997: J Weissenberger; Joachim P Steinbach; G Malin; S Spada; Thomas Rülicke; Adriano Aguzzi
Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice.
Oncogene 1997;14(17):2005-13.
1997: Adriano Aguzzi
Neuro-immune connection in spread of prions in the body?
Lancet 1997;349(9054):742-3.
1997: I Vajtai; Z Varga; Adriano Aguzzi
Pleomorphic xanthoastrocytoma with gangliogliomatous component.
Pathology, research and practice 1997;193(9):617-21.
1996: Z Varga; I Vajtai; Adriano Aguzzi
The standard isoform of CD44 is preferentially expressed in atypical papillomas and carcinomas of the choroid plexus.
Pathology, research and practice 1996;192(12):1225-31.
1996: Charles Weissmann; Marc Fischer; Alex J Raeber; Hansruedi Büeler; A Sailer; David H Shmerling; Thomas Rülicke; Sebastian Brandner; Adriano Aguzzi
The use of transgenic mice in the investigation of transmissible spongiform encephalopathies.
International journal of experimental pathology 1996;77(6):283-93.
1996: Sebastian Brandner; Alex J Raeber; A Sailer; Thomas Blättler; Marc Fischer; Charles Weissmann; Adriano Aguzzi
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13148-51.
1996: S Isenmann; Sebastian Brandner; Adriano Aguzzi
Neuroectodermal grafting: a new tool for the study of neurodegenerative diseases.
Histology and histopathology 1996;11(4):1063-73.
1996: Josef Magyar; Rudolf Martini; T Ruelicke; Adriano Aguzzi; K Adlkofer; Z Dembic; Jürgen Zielasek; Klaus V Toyka; Ueli Suter
Impaired differentiation of Schwann cells in transgenic mice with increased PMP22 gene dosage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(17):5351-60.
1996: Z Varga; I Vajtai; S Marino; B Schäuble; Y Yonekawa; Adriano Aguzzi
Tubular adenoma of the choroid plexus: evidence for glandular differentiation of the neuroepithelium.
Pathology, research and practice 1996;192(8):840-4.
1996: I Vajtai; Z Varga; Adriano Aguzzi
MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus.
Histopathology 1996;29(2):147-51.
1996: Adriano Aguzzi
Pathogenesis of spongiform encephalopathies: an update.
International archives of allergy and immunology 1996;110(2):99-106.
1996: S Isenmann; Sebastian Brandner; G Kühne; J Boner; Adriano Aguzzi
Comparative in vivo and pathological analysis of the blood-brain barrier in mouse telencephalic transplants.
Neuropathology and applied neurobiology 1996;22(2):118-28.
1996: S Isenmann; Sebastian Brandner; Ulrich Sure; Adriano Aguzzi
Telencephalic transplants in mice: characterization of growth and differentiation patterns.
Neuropathology and applied neurobiology 1996;22(2):108-17.
1996: Adriano Aguzzi; Charles Weissmann
Sleepless in Bologna: transmission of fatal familial insomnia.
Trends in microbiology 1996;4(4):129-31; discussion 131-2.
1996: Jean-Marc Fritschy; Sebastian Brandner; Adriano Aguzzi; M Koedood; Bernhard Luscher; P J Mitchell
Brain cell type specificity and gliosis-induced activation of the human cytomegalovirus immediate-early promoter in transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(7):2275-82.
1996: Marc Fischer; Thomas Rülicke; Alex J Raeber; A Sailer; M Moser; Bruno Oesch; Sebastian Brandner; Adriano Aguzzi; Charles Weissmann
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.
The EMBO journal 1996;15(6):1255-64.
1996: Adriano Aguzzi; Sebastian Brandner; S Marino; Joachim P Steinbach
Transgenic and knockout mice in the study of neurodegenerative diseases.
Journal of molecular medicine (Berlin, Germany) 1996;74(3):111-26.
1996: R R Tschopp; Sebastian Brandner; S Marino; K Bothe; Ivan Horak; Axel Rethwilm; Adriano Aguzzi
Analysis of the determinants of neurotropism and neurotoxicity of HFV in transgenic mice.
Virology 1996;216(2):338-46.
1996: Sebastian Brandner; S Isenmann; Alex J Raeber; Marc Fischer; A Sailer; Y Kobayashi; S Marino; Charles Weissmann; Adriano Aguzzi
Normal host prion protein necessary for scrapie-induced neurotoxicity.
Nature 1996;379(6563):339-43.
1996: U Müller; N Cristina; Z W Li; David P Wolfer; Hans-Peter Lipp; Thomas Rülicke; Sebastian Brandner; Adriano Aguzzi; C Weissman
Mice homozygous for a modified beta-amyloid precursor protein (beta APP) gene show impaired behavior and high incidence of agenesis of the corpus callosum.
Annals of the New York Academy of Sciences 1996;777():65-73.
1996: Charles Weissmann; Marc Fischer; Alex J Raeber; Hansruedi Büeler; A Sailer; David H Shmerling; Thomas Rülicke; Sebastian Brandner; Adriano Aguzzi
The role of PrP in pathogenesis of experimental scrapie.
Cold Spring Harbor symposia on quantitative biology 1996;61():511-22.
1996: Adriano Aguzzi; S Marino; R Tschopp; Axel Rethwilm
Regulation of expression and pathogenic potential of human foamy virus in vitro and in transgenic mice.
Current topics in microbiology and immunology 1996;206():243-73.
1995: Y L Yang; Luiz F L Reis; Jovan Pavlovic; Adriano Aguzzi; R Schäfer; A Kumar; Bryan R G Williams; M Aguet; Charles Weissmann
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
The EMBO journal 1995;14(24):6095-106.
1995: S Isenmann; M Molthagen; Sebastian Brandner; Udo Bartsch; G Kühne; Josef Magyar; Ulrich Sure; Melitta Schachner; Adriano Aguzzi
The AMOG/beta 2 subunit of Na,K-ATPase is not necessary for long-term survival of telencephalic grafts.
Glia 1995;15(4):377-88.
1995: Adriano Aguzzi; Sebastian Brandner; S Isenmann; Joachim P Steinbach; Ulrich Sure
Transgenic and gene disruption techniques in the study of neurocarcinogenesis.
Glia 1995;15(3):348-64.
1995: K Adlkofer; Rudolf Martini; Adriano Aguzzi; Jürgen Zielasek; Klaus V Toyka; Ueli Suter
Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice.
Nature genetics 1995;11(3):274-80.
1995: Wojciech Biernat; Adriano Aguzzi; Ulrich Sure; J W Grant; Paul Kleihues; Monika E Hegi
Identical mutations of the p53 tumor suppressor gene in the gliomatous and the sarcomatous components of gliosarcomas suggest a common origin from glial cells.
Journal of neuropathology and experimental neurology 1995;54(5):651-6.
1995: U Günther; J Benson; Dietmar Benke; Jean-Marc Fritschy; G Reyes; F Knoflach; Florence Crestani; Adriano Aguzzi; M Arigoni; Y Lang
Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7749-53.
1995: S Marino; C Kretschmer; Sebastian Brandner; C Cavard; A Zider; Pascale Briand; S Isenmann; E F Wagner; Adriano Aguzzi
Activation of HIV transcription by human foamy virus in transgenic mice.
Laboratory investigation; a journal of technical methods and pathology 1995;73(1):103-10.
1995: Zbynek Kozmik; Ulrich Sure; D Rüedi; Meinrad Busslinger; Adriano Aguzzi
Deregulated expression of PAX5 in medulloblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5709-13.
1995: M Hergersberg; Koichi Matsuo; M Gassmann; Walter Schaffner; Bernhard Lüscher; Thomas Rülicke; Adriano Aguzzi
Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice.
Human molecular genetics 1995;4(3):359-66.
1995: M Kiess; B Scharm; Adriano Aguzzi; A Hajnal; R Klemenz; I Schwarte-Waldhoff; R Schäfer
Expression of ril, a novel LIM domain gene, is down-regulated in Hras-transformed cells and restored in phenotypic revertants.
Oncogene 1995;10(1):61-8.
1995: Ulrich Sure; Helmut Bertalanffy; S Isenmann; Sebastian Brandner; W J Berghorn; Werner Seeger; Adriano Aguzzi
Secondary manifestation of medulloblastoma: metastases and local recurrences in 66 patients.
Acta neurochirurgica 1995;136(3-4):117-26.
1994: U Müller; N Cristina; Z W Li; David P Wolfer; Hans-Peter Lipp; Thomas Rülicke; Sebastian Brandner; Adriano Aguzzi; Charles Weissmann
Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene.
Cell 1994;79(5):755-65.
1994: Hansruedi Büeler; Alex J Raeber; A Sailer; Marc Fischer; Adriano Aguzzi; Charles Weissmann
High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene.
Molecular medicine (Cambridge, Mass.) 1994;1(1):19-30.
1994: Josef Magyar; Udo Bartsch; Z Q Wang; N Howells; Adriano Aguzzi; E F Wagner; Melitta Schachner
Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase.
The Journal of cell biology 1994;127(3):835-45.
1994: A Sailer; Hansruedi Büeler; Marc Fischer; Adriano Aguzzi; Charles Weissmann
No propagation of prions in mice devoid of PrP.
Cell 1994;77(7):967-8.
1994: Charles Weissmann; Hansruedi Büeler; Marc Fischer; A Sailer; Adriano Aguzzi; M Aguet
PrP-deficient mice are resistant to scrapie.
Annals of the New York Academy of Sciences 1994;724():235-40.
1994: F Kiefer; I Anhauser; P Soriano; Adriano Aguzzi; S A Courtneidge; E F Wagner
Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.
Current biology : CB 1994;4(2):100-9.
1994: Otmar D Wiestler; O Brüstle; Robert Eibl; Herbert Radner; Adriano Aguzzi; Paul Kleihues
Oncogene transfer into the brain.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1994;135():55-66.
1994: Adriano Aguzzi; Sebastian Brandner; Ulrich Sure; D Rüedi; S Isenmann
Transgenic and knock-out mice: models of neurological disease.
Brain pathology (Zurich, Switzerland) 1994;4(1):3-20.
1994: S Isenmann; Sebastian Brandner; Ulrich Sure; Josef Magyar; Melitta Schachner; Adriano Aguzzi
[Morphology and development of neural transplants of AMOG-deficient mice].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():433-7.
1994: Adriano Aguzzi
[Neurotoxicity of human foamy virus in transgenic mice].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():180-8.
1993: Charles Weissmann; Hansruedi Büeler; A Sailer; Marc Fischer; M Aguet; Adriano Aguzzi
Role of PrP in prion diseases.
British medical bulletin 1993;49(4):995-1011.
1993: Hansruedi Büeler; Adriano Aguzzi; A Sailer; R A Greiner; P Autenried; M Aguet; Charles Weissmann
Mice devoid of PrP are resistant to scrapie.
Cell 1993;73(7):1339-47.
1993: Adriano Aguzzi
The foamy virus family: molecular biology, epidemiology and neuropathology.
Biochimica et biophysica acta 1993;1155(1):1-24.
1993: Adriano Aguzzi; E F Wagner; K O Netzer; K Bothe; I Anhauser; Axel Rethwilm
Human foamy virus proteins accumulate in neurons and induce multinucleated giant cells in the brain of transgenic mice.
The American journal of pathology 1993;142(4):1061-71.
1993: K O Netzer; A Schliephake; B Maurer; R Watanabe; Adriano Aguzzi; Axel Rethwilm
Identification of pol-related gene products of human foamy virus.
Virology 1993;192(1):336-8.
1992: Otmar D Wiestler; O Brüstle; Robert Eibl; Herbert Radner; A Von Deimling; K Plate; Adriano Aguzzi; Paul Kleihues
A new approach to the molecular basis of neoplastic transformation in the brain.
Neuropathology and applied neurobiology 1992;18(5):443-53.
1992: B Adams; P Dörfler; Adriano Aguzzi; Zbynek Kozmik; P Urbánek; I Maurer-Fogy; Meinrad Busslinger
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
Genes & development 1992;6(9):1589-607.
1992: Otmar D Wiestler; Adriano Aguzzi; Markus Schneemann; Robert Eibl; A von Deimling; Paul Kleihues
Oncogene complementation in fetal brain transplants.
Cancer research 1992;52(13):3760-7.
1992: O Brüstle; Adriano Aguzzi; D Talarico; Claudio Basilico; Paul Kleihues; Otmar D Wiestler
Angiogenic activity of the K-fgf/hst oncogene in neural transplants.
Oncogene 1992;7(6):1177-83.
1992: Adriano Aguzzi; K Bothe; I Anhauser; Ivan Horak; Axel Rethwilm; E F Wagner
Expression of human foamy virus is differentially regulated during development in transgenic mice.
The New biologist 1992;4(3):225-37.
1992: Adriano Aguzzi; K Bothe; E F Wagner; Axel Rethwilm; Ivan Horak
Human foamy virus: an underestimated neuropathogen?
Brain pathology (Zurich, Switzerland) 1992;2(1):61-9.
1992: Otmar D Wiestler; O Brüstle; Robert Eibl; Herbert Radner; Adriano Aguzzi; Paul Kleihues
Retrovirus-mediated oncogene transfer into neural transplants.
Brain pathology (Zurich, Switzerland) 1992;2(1):47-59.
1991: K Bothe; Adriano Aguzzi; H Lassmann; Axel Rethwilm; Ivan Horak
Progressive encephalopathy and myopathy in transgenic mice expressing human foamy virus genes.
Science (New York, N.Y.) 1991;253(5019):555-7.
1991: Adriano Aguzzi; Paul Kleihues; K Heckl; Otmar D Wiestler
Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer.
Oncogene 1991;6(1):113-8.
1990: Paul Kleihues; Adriano Aguzzi; Otmar D Wiestler
Cellular and molecular aspects of neurocarcinogenesis.
Toxicologic pathology 1990;18(1 Pt 2):193-203.
1989: Otmar D Wiestler; Adriano Aguzzi; R L Williams; E F Wagner; C A Boulter; Paul Kleihues
Tumour induction in fetal brain transplants exposed to the viral oncogenes polyoma middle T and v-src.
IARC scientific publications 1989;(96):267-74.
1989: Paul Kleihues; T Shibata; Adriano Aguzzi; Peter C Burger
Cell-specific brain tumour induction in neural transplants: evidence for multistep carcinogenesis in the nervous system.
IARC scientific publications 1989;(96):121-9.
1988: Peter C Burger; T Shibata; Adriano Aguzzi; Paul Kleihues
Selective induction by N-nitrosoethylurea of oligodendrogliomas in fetal forebrain transplants.
Cancer research 1988;48(10):2871-5.