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Paul Borm

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Paul J A Borm; Lang Tran; Ken Donaldson
The carcinogenic action of crystalline silica: a review of the evidence supporting secondary inflammation-driven genotoxicity as a principal mechanism.
Hans Orru; Veljo Kimmel; Ulle Kikas; Argo Soon; Nino Künzli; Roel P F Schins; Paul J A Borm; Bertil Forsberg
Elemental composition and oxidative properties of PM(2.5) in Estonia in relation to origin of air masses - results from the ECRHS II in Tartu.
Pasi I Jalava; Maija-Riitta Hirvonen; Markus Sillanpää; Arto S Pennanen; Mikko S Happo; Risto Hillamo; Flemming R Cassee; Miriam Gerlofs-Nijland; Paul J A Borm; Roel P F Schins; N A H Janssen; Raimo O Salonen
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line.

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2011: Paul J A Borm; Lang Tran; Ken Donaldson
The carcinogenic action of crystalline silica: a review of the evidence supporting secondary inflammation-driven genotoxicity as a principal mechanism.
Critical reviews in toxicology 2011;41(9):756-70.
2010: Hans Orru; Veljo Kimmel; Ulle Kikas; Argo Soon; Nino Künzli; Roel P F Schins; Paul J A Borm; Bertil Forsberg
Elemental composition and oxidative properties of PM(2.5) in Estonia in relation to origin of air masses - results from the ECRHS II in Tartu.
The Science of the total environment 2010;408(7):1515-22.
2009: Pasi I Jalava; Maija-Riitta Hirvonen; Markus Sillanpää; Arto S Pennanen; Mikko S Happo; Risto Hillamo; Flemming R Cassee; Miriam Gerlofs-Nijland; Paul J A Borm; Roel P F Schins; N A H Janssen; Raimo O Salonen
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line.
Inhalation toxicology 2009;21(12):994-1006.
2009: Miriam E Gerlofs-Nijland; Melina Rummelhard; john boere; Daan L A C Leseman; Rodger Duffin; Roel P F Schins; Paul J A Borm; Markus Sillanpää; Raimo O Salonen; Flemming R Cassee
Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents.
Environmental science & technology 2009;43(13):4729-36.
2009: Sebastian Kos; Rolf W Huegli; Eugen Hofmann; Harald H Quick; Hilmar Kuehl; Stephanie Aker; Gernot M Kaiser; Paul J A Borm; Augustinus L Jacob; Deniz Bilecen
First magnetic resonance imaging-guided aortic stenting and cava filter placement using a polyetheretherketone-based magnetic resonance imaging-compatible guidewire in swine: proof of concept.
Cardiovascular and interventional radiology 2009;32(3):514-21.
2009: Sebastian Kos; Rolf W Huegli; Eugen Hofmann; Harald H Quick; Hilmar Kuehl; Stephanie Aker; Gernot M Kaiser; Paul J A Borm; Augustinus L Jacob; Deniz Bilecen
MR-compatible polyetheretherketone-based guide wire assisting MR-guided stenting of iliac and supraaortic arteries in swine: feasibility study.
Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy 2009;18(3):181-8.
2009: Ken Donaldson; Paul J A Borm; Vincent Castranova; Mary Gulumian
The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles.
Particle and fibre toxicology 2009;6():13.
2008: Petra Haberzettl; Roel P F Schins; Doris Höhr; Verena Wilhelmi; Paul J A Borm; Catrin Albrecht
Impact of the FcgammaII-receptor on quartz uptake and inflammatory response by alveolar macrophages.
American journal of physiology. Lung cellular and molecular physiology 2008;294(6):L1137-48.
2008: Hui Li; Damien van Berlo; Tingming Shi; Günter Speit; Ad M Knaapen; Paul J A Borm; Catrin Albrecht; Roel P F Schins
Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line.
Toxicology and applied pharmacology 2008;227(1):115-24.
2008: Wim H De Jong; Paul J A Borm
Drug delivery and nanoparticles:applications and hazards.
International journal of nanomedicine 2008;3(2):133-49.
2008: Björn Crüts; Anique Driessen; Ludo van Etten; Håkan Törnqvist; Anders Blomberg; Thomas Sandström; Nicholas L Mills; Paul J A Borm
Reply to comment on Cruts et al. (2008), "Exposure to diesel exhaust induces changes in EEG in human volunteers" by Valberg et al.
Particle and fibre toxicology 2008;5():11.
2008: Björn Crüts; Ludo van Etten; Håkan Törnqvist; Anders Blomberg; Thomas Sandström; Nicholas L Mills; Paul J A Borm
Exposure to diesel exhaust induces changes in EEG in human volunteers.
Particle and fibre toxicology 2008;5():4.
2008: Jon G Ayres; Paul J A Borm; Flemming R Cassee; Vincent Castranova; Ken Donaldson; Andy Ghio; Roy M Harrison; Robert Hider; Frank Kelly; Ingeborg M Kooter; Francelyne Marano; Robert L Maynard; Ian S Mudway; Andre E Nel; Constantinos Sioutas; Steve Smith; Armelle Baeza-Squiban; Art Cho; Sean Duggan; John R Froines
Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement.
Inhalation toxicology 2008;20(1):75-99.
2008: Ken Donaldson; Paul J A Borm; G Oberdorster; Kent E Pinkerton; Vicki Stone; C L Tran
Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles: the key role of the proximal alveolar region.
Inhalation toxicology 2008;20(1):53-62.
2007: Seema Singh; Tingming Shi; Rodger Duffin; Catrin Albrecht; Damien van Berlo; Doris Höhr; Bice Fubini; Gianmario Martra; Ivana Fenoglio; Paul J A Borm; Roel P F Schins
Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles.
Toxicology and applied pharmacology 2007;222(2):141-51.
2007: Petra Haberzettl; Rodger Duffin; Ursula Krämer; Doris Höhr; Roel P F Schins; Paul J A Borm; Catrin Albrecht
Actin plays a crucial role in the phagocytosis and biological response to respirable quartz particles in macrophages.
Archives of toxicology 2007;81(7):459-70.
2007: David B Warheit; Paul J A Borm; Christa Hennes; Jürgen Lademann
Testing strategies to establish the safety of nanomaterials: conclusions of an ECETOC workshop.
Inhalation toxicology 2007;19(8):631-43.
2007: Hui Li; Petra Haberzettl; Catrin Albrecht; Doris Höhr; Ad M Knaapen; Paul J A Borm; Roel P F Schins
Inhibition of the mitochondrial respiratory chain function abrogates quartz induced DNA damage in lung epithelial cells.
Mutation research 2007;617(1-2):46-57.
2007: Claire de Burbure; Jean-François Heilier; J Nève; A Becker; C Albrecht; Paul J A Borm; Jolanta Gromadzinska; Wojciech WASOWICZ; Konrad Rydzynski; AM Bernard
Lung permeability, antioxidant status, and NO2 inhalation: a selenium supplementation study in rats.
Journal of toxicology and environmental health. Part A 2007;70(3-4):284-94.
2007: Paul J A Borm; Frank Kelly; Nino Künzli; Roel P F Schins; Kenneth Donaldson
Oxidant generation by particulate matter: from biologically effective dose to a promising, novel metric.
Occupational and environmental medicine 2007;64(2):73-4.
2007: Catrin Albrecht; Doris Höhr; Petra Haberzettl; Andrea Becker; Paul J A Borm; Roel P F Schins
Surface-dependent quartz uptake by macrophages: potential role in pulmonary inflammation and lung clearance.
Inhalation toxicology 2007;19 Suppl 1():39-48.
2007: Brooke T Mossman; Paul J A Borm; Vincent Castranova; Daniel L Costa; Kenneth Donaldson; Steven R Kleeberger
Mechanisms of action of inhaled fibers, particles and nanoparticles in lung and cardiovascular diseases.
Particle and fibre toxicology 2007;4():4.
2006: M Gulumian; Paul J A Borm; V Vallyathan; V Castranova; K Donaldson; G Nelson; J Murray
Mechanistically identified suitable biomarkers of exposure, effect, and susceptibility for silicosis and coal-worker's pneumoconiosis: a comprehensive review.
Journal of toxicology and environmental health. Part B, Critical reviews 2006;9(5):357-95.
2006: Paul J A Borm; Detlef Müller-Schulte
Nanoparticles in drug delivery and environmental exposure: same size, same risks?
Nanomedicine (London, England) 2006;1(2):235-49.
2006: Karim Bagate; James J Meiring; Miriam E Gerlofs-Nijland; Flemming R Cassee; Herbert Wiegand; Alvaro Roman Osornio-Vargas; Paul J A Borm
Ambient particulate matter affects cardiac recovery in a Langendorff ischemia model.
Inhalation toxicology 2006;18(9):633-43.
2006: Ad M Knaapen; Nejla Güngör; Roel P F Schins; Paul J A Borm; Frederik J Van Schooten
Neutrophils and respiratory tract DNA damage and mutagenesis: a review.
Mutagenesis 2006;21(4):225-36.
2006: Susy M Braun; Anna J Beurskens; Paul J A Borm; Thomas Schack; Derick T Wade
The effects of mental practice in stroke rehabilitation: a systematic review.
Archives of physical medicine and rehabilitation 2006;87(6):842-52.
2006: Nino Künzli; Ian S Mudway; Thomas Götschi; Tingming Shi; Frank Kelly; Sarah Cook; Peter Burney; Bertil Forsberg; Jim Gauderman; Marianne E Hazenkamp; Joachim Heinrich; Deborah Jarvis; Dan Norbäck; Felix Payo-Losa; Albino Poli; Jordi Sunyer; Paul J A Borm
Comparison of oxidative properties, light absorbance, total and elemental mass concentration of ambient PM2.5 collected at 20 European sites.
Environmental health perspectives 2006;114(5):684-90.
2006: Andrea Becker; Catrin Albrecht; Ad M Knaapen; Roel P F Schins; Doris Höhr; Kirstin Ledermann; Paul J A Borm
Induction of CYP1A1 in rat lung cells following in vivo and in vitro exposure to quartz.
Archives of toxicology 2006;80(5):258-68.
2006: Tingming Shi; Rodger Duffin; Paul J A Borm; Hui Li; Christel Weishaupt; Roel P F Schins
Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations.
Environmental research 2006;101(1):18-24.
2006: Paul J A Borm; Frederick C Klaessig; Timothy D Landry; Brij Moudgil; Jürgen Pauluhn; Karluss Thomas; Remi Trottier; Stewart Wood
Research strategies for safety evaluation of nanomaterials, part V: role of dissolution in biological fate and effects of nanoscale particles.
Toxicological sciences : an official journal of the Society of Toxicology 2006;90(1):23-32.
2006: Stefan Geh; Raif Yücel; Rodger Duffin; Catrin Albrecht; Paul J A Borm; Lorenz Armbruster; Monika Raulf-Heimsoth; Thomas Brüning; Eik Hoffmann; Albert W Rettenmeier; Elke Dopp
Cellular uptake and cytotoxic potential of respirable bentonite particles with different quartz contents and chemical modifications in human lung fibroblasts.
Archives of toxicology 2006;80(2):98-106.
2006: Karim Bagate; James J Meiring; Miriam E Gerlofs-Nijland; Flemming R Cassee; Paul J A Borm
Signal transduction pathways involved in particulate matter induced relaxation in rat aorta--spontaneous hypertensive versus Wistar Kyoto rats.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(1):52-62.
2006: Paul J A Borm; David Robbins; Stephan Haubold; Thomas Kuhlbusch; Heinz Fissan; Ken Donaldson; Roel P F Schins; Vicki Stone; Wolfgang G Kreyling; Jurgen Lademann; Jean Krutmann; David B Warheit; Eva Oberdorster
The potential risks of nanomaterials: a review carried out for ECETOC.
Particle and fibre toxicology 2006;3():11.
2005: Ad M Knaapen; Roel P F Schins; Paul J A Borm; Frederik J Van Schooten
Nitrite enhances neutrophil-induced DNA strand breakage in pulmonary epithelial cells by inhibition of myeloperoxidase.
Carcinogenesis 2005;26(9):1642-8.
2005: James J Meiring; Paul J A Borm; Karim Bagate; Manuela Semmler; Jürgen Seitz; Shinji Takenaka; Wolfgang G Kreyling
The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung.
Particle and fibre toxicology 2005;2():3.
2005: Paul J A Borm; gonca cakmak demircigil; Erich Jermann; Christel Weishaupt; Pascal Kempers; Frederik J Van Schooten; Günter Oberdörster; Roel P F Schins
Formation of PAH-DNA adducts after in vivo and vitro exposure of rats and lung cells to different commercial carbon blacks.
Toxicology and applied pharmacology 2005;205(2):157-67.
2005: Catrin Albrecht; Ad M Knaapen; Andrea Becker; Doris Höhr; Petra Haberzettl; Frederik J Van Schooten; Paul J A Borm; Roel P F Schins
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung.
Respiratory research 2005;6():129.
2004: Roel P F Schins; Dünya Polat; Jutta Begerow; M Turfeld; Andrea Becker; Paul J A Borm
Platinum levels in nasal lavage fluid as a biomarker for traffic-related exposure and inflammation in children.
The Science of the total environment 2004;334-335():447-55.
2004: Frank Schaumann; Paul J A Borm; Andreas Herbrich; Johannes Knoch; Mike Pitz; Roel P F Schins; Birgit Luettig; Jens Hohlfeld; Joachim Heinrich; Norbert Krug
Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects.
American journal of respiratory and critical care medicine 2004;170(8):898-903.
2004: Catrin Albrecht; Paul J A Borm; Klaus Unfried
Signal transduction pathways relevant for neoplastic effects of fibrous and non-fibrous particles.
Mutation research 2004;553(1-2):23-35.
2004: K Donaldson; V Stone; C L Tran; Wolfgang G Kreyling; Paul J A Borm
Nanotoxicology.
Occupational and environmental medicine 2004;61(9):727-8.
2004: Catrin Albrecht; Roel P F Schins; Doris Höhr; Andrea Becker; Tingming Shi; Ad M Knaapen; Paul J A Borm
Inflammatory time course after quartz instillation: role of tumor necrosis factor-alpha and particle surface.
American journal of respiratory cell and molecular biology 2004;31(3):292-301.
2004: Joachim Bruch; Steffeni Rehn; Bernd Rehn; Paul J A Borm; Bice Fubini
Variation of biological responses to different respirable quartz flours determined by a vector model.
International journal of hygiene and environmental health 2004;207(3):203-16.
2004: Karim Bagaté; James J Meiring; Flemming R Cassee; Paul J A Borm
The effect of particulate matter on resistance and conductance vessels in the rat.
Inhalation toxicology 2004;16(6-7):431-6.
2004: Paul J A Borm; Roel P F Schins; Catrin Albrecht
Inhaled particles and lung cancer, part B: paradigms and risk assessment.
International journal of cancer. Journal international du cancer 2004;110(1):3-14.
2004: Karim Bagate; James J Meiring; Miriam E Gerlofs-Nijland; Renaud Vincent; Flemming R Cassee; Paul J A Borm
Vascular effects of ambient particulate matter instillation in spontaneous hypertensive rats.
Toxicology and applied pharmacology 2004;197(1):29-39.
2004: Ad M Knaapen; Paul J A Borm; Catrin Albrecht; Roel P F Schins
Inhaled particles and lung cancer. Part A: Mechanisms.
International journal of cancer. Journal international du cancer 2004;109(6):799-809.
2004: Paul J A Borm; Wolfgang G Kreyling
Toxicological hazards of inhaled nanoparticles--potential implications for drug delivery.
Journal of nanoscience and nanotechnology 2004;4(5):521-31.
2004: Frederik J Van Schooten; Agnes W Boots; Ad M Knaapen; Roger Godschalk; Lou M Maas; Paul J A Borm; Marjolein Drent; Jan A Jacobs
Myeloperoxidase (MPO) -463G->A reduces MPO activity and DNA adduct levels in bronchoalveolar lavages of smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):828-33.
2004: Evelyn Tjoe Nij; Doris Höhr; Paul J A Borm; Igor Burstyn; Judith Spierings; Friso Steffens; Mieke Lumens; Ton Spee; Dick Heederik
Variability in quartz exposure in the construction industry: implications for assessing exposure-response relations.
Journal of occupational and environmental hygiene 2004;1(3):191-8.
2004: Roel P F Schins; Janet H Lightbody; Paul J A Borm; Tingming Shi; Ken Donaldson; Vicki Stone
Inflammatory effects of coarse and fine particulate matter in relation to chemical and biological constituents.
Toxicology and applied pharmacology 2004;195(1):1-11.
2004: gonca cakmak demircigil; Roel P F Schins; Tingming Shi; Ivana Fenoglio; Bice Fubini; Paul J A Borm
In vitro genotoxicity assessment of commercial quartz flours in comparison to standard DQ12 quartz.
International journal of hygiene and environmental health 2004;207(2):105-13.
2004: Bice Fubini; Ivana Fenoglio; Raffaella Ceschino; Mara Ghiazza; Gianmario Martra; Maura Tomatis; Paul J A Borm; Roel P F Schins; Joachim Bruch
Relationship between the state of the surface of four commercial quartz flours and their biological activity in vitro and in vivo.
International journal of hygiene and environmental health 2004;207(2):89-104.
2004: David M Brown; Ken Donaldson; Paul J A Borm; Roel P F Schins; M Dehnhardt; Peter S Gilmour; Luis A Jimenez; Vicki Stone
Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
American journal of physiology. Lung cellular and molecular physiology 2004;286(2):L344-53.
2003: Danielle C L Mohren; Gerard M H Swaen; Ijmert Kant; Ludovic van Amelsvoort; Paul J A Borm; Jochem M D Galama
Common infections and the role of burnout in a Dutch working population.
Journal of psychosomatic research 2003;55(3):201-8.
2003: Tingming Shi; Roel P F Schins; Ad M Knaapen; Thomas Kuhlbusch; Mike Pitz; Joachim Heinrich; Paul J A Borm
Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition.
Journal of environmental monitoring : JEM 2003;5(4):550-6.
2003: Ken Donaldson; Vicki Stone; Paul J A Borm; Luis A Jimenez; Peter S Gilmour; Roel P F Schins; Ad M Knaapen; Irfan Rahman; Stephen P Faux; David M Brown; William MacNee
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10).
Free radical biology & medicine 2003;34(11):1369-82.
2003: Tingming Shi; Ad M Knaapen; Jutta Begerow; W Birmili; Paul J A Borm; Roel P F Schins
Temporal variation of hydroxyl radical generation and 8-hydroxy-2'-deoxyguanosine formation by coarse and fine particulate matter.
Occupational and environmental medicine 2003;60(5):315-21.
2003: Danielle C L Mohren; Gerard M H Swaen; Ludovic van Amelsvoort; Paul J A Borm; Jochem M D Galama
Job insecurity as a risk factor for common infections and health complaints.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2003;45(2):123-9.
2002: Catrin Albrecht; Paul J A Borm; Brigitte Adolf; Cynthia R Timblin; Brooke T Mossman
In vitro and in vivo activation of extracellular signal-regulated kinases by coal dusts and quartz silica.
Toxicology and applied pharmacology 2002;184(1):37-45.
2002: Roel P F Schins; Rodger Duffin; Doris Höhr; Ad M Knaapen; Tingming Shi; Christel Weishaupt; Vicki Stone; Ken Donaldson; Paul J A Borm
Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.
Chemical research in toxicology 2002;15(9):1166-73.
2002: Roger Godschalk; Dorien E M Feldker; Paul J A Borm; Emiel F M Wouters; Frederik J Van Schooten
Body mass index modulates aromatic DNA adduct levels and their persistence in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(8):790-3.
2002: Ad M Knaapen; Catrin Albrecht; Andrea Becker; Doris Höhr; Astrid Winzer; Guido R M M Haenen; Paul J A Borm; Roel P F Schins
DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation.
Carcinogenesis 2002;23(7):1111-20.
2002: Roel P F Schins; Ad M Knaapen; gonca cakmak demircigil; Tingming Shi; Christel Weishaupt; Paul J A Borm
Oxidant-induced DNA damage by quartz in alveolar epithelial cells.
Mutation research 2002;517(1-2):77-86.
2002: Ad M Knaapen; Tingming Shi; Paul J A Borm; Roel P F Schins
Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter.
Molecular and cellular biochemistry 2002;234-235(1-2):317-26.
2002: Ad M Knaapen; Roel P F Schins; Dünya Polat; Andrea Becker; Paul J A Borm
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells.
Molecular and cellular biochemistry 2002;234-235(1-2):143-51.
2002: Paul J A Borm; M Jetten; S Hidayat; N van de Burgh; P Leunissen; IJmert Kant; R Houba; H Soeprapto
Respiratory symptoms, lung function, and nasal cellularity in Indonesian wood workers: a dose-response analysis.
Occupational and environmental medicine 2002;59(5):338-44.
2002: Doris Höhr; Yvonne Steinfartz; Roel P F Schins; Ad M Knaapen; Gianmario Martra; Bice Fubini; Paul J A Borm
The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat.
International journal of hygiene and environmental health 2002;205(3):239-44.
2002: Dünya Polat; Georg Eberwein; Andrea Becker; Christel Weishaupt; Roel P F Schins; Ulrich Ranft; Paul J A Borm
Ambient exposure and nasal inflammation in adults and children--a preliminary analysis.
International journal of hygiene and environmental health 2002;205(3):229-34.
2002: Paul J A Borm
Particle toxicology: from coal mining to nanotechnology.
Inhalation toxicology 2002;14(3):311-24.
2002: Kevin E Driscoll; Janet M Carter; Paul J A Borm
Antioxidant defense mechanisms and the toxicity of fibrous and nonfibrous particles.
Inhalation toxicology 2002;14(1):101-18.
2002: Paul J A Borm
Munich workshop on evaluation of fiber and particle toxicity: an introduction.
Inhalation toxicology 2002;14(1):1-3.
2002: Paul J A Borm; Lang Tran
From quartz hazard to quartz risk: the coal mines revisited.
The Annals of occupational hygiene 2002;46(1):25-32.
2001: Rodger Duffin; Peter S Gilmour; Roel P F Schins; Anna Clouter; Keith Guy; David M Brown; William MacNee; Paul J A Borm; Ken Donaldson; Vicki Stone
Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation.
Toxicology and applied pharmacology 2001;176(1):10-7.
2001: Benoit Nemery; A Bast; Jürgen Behr; Paul J A Borm; S J Bourke; Philippe Camus; P De Vuyst; H M Jansen; V L Kinnula; D Lison; Olavi Pelkonen; C Saltini
Interstitial lung disease induced by exogenous agents: factors governing susceptibility.
The European respiratory journal. Supplement 2001;32():30s-42s.
2001: Paul J A Borm; R P Schins
Genotype and phenotype in susceptibility to coal workers' pneumoconiosis. the use of cytokines in perspective.
The European respiratory journal. Supplement 2001;32():127s-133s.
2001: Anna Clouter; David Brown; Doris Höhr; Paul J A Borm; Ken Donaldson
Inflammatory effects of respirable quartz collected in workplaces versus standard DQ12 quartz: particle surface correlates.
Toxicological sciences : an official journal of the Society of Toxicology 2001;63(1):90-8.
2001: Helmut Greim; Paul J A Borm; Roel P F Schins; K Donaldson; Kevin E Driscoll; Andrea Hartwig; E Kuempel; G Oberdörster; Günter Speit
Toxicity of fibers and particles. Report of the workshop held in Munich, Germany, 26-27 October 2000.
Inhalation toxicology 2001;13(9):737-54.
2001: Ad M Knaapen; G J den Hartog; A Bast; Paul J A Borm
Ambient particulate matter induces relaxation of rat aortic rings in vitro.
Human & experimental toxicology 2001;20(5):259-65.
2001: Catrin Albrecht; B Adolf; Christel Weishaupt; Doris Höhr; I Zeitträger; J Friemann; Paul J A Borm
Clara-cell hyperplasia after quartz and coal-dust instillation in rat lung.
Inhalation toxicology 2001;13(3):191-205.
2001: Danielle C L Mohren; Gerard M H Swaen; Ijmert Kant; Paul J A Borm; Jochem M D Galama
Associations between infections and fatigue in a Dutch working population: results of the Maastricht Cohort Study on Fatigue at Work.
European journal of epidemiology 2001;17(12):1081-7.
2001: Ken Donaldson; Vicki Stone; Rodger Duffin; Anna Clouter; Roel P F Schins; Paul J A Borm
The quartz hazard: effects of surface and matrix on inflammogenic activity.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2001;20 Suppl 1():109-18.
2001: Danielle C L Mohren; Gerard M H Swaen; Paul J A Borm; A Bast; Jochem M D Galama
Psychological job demands as a risk factor for common cold in a Dutch working population.
Journal of psychosomatic research 2001;50(1):21-7.
2000: R P Schins; H Emmen; L Hoogendijk; Paul J A Borm
Nasal inflammatory and respiratory parameters in human volunteers during and after repeated exposure to chlorine.
The European respiratory journal 2000;16(4):626-32.
2000: Vicki Stone; M Tuinman; Joannis Vamvakopoulos; J Shaw; D Brown; S Petterson; Stephen P Faux; Paul J A Borm; William MacNee; F Michaelangeli; Ken Donaldson
Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black.
The European respiratory journal 2000;15(2):297-303.
1999: Jan M S van Maanen; Paul J A Borm; Ad M Knaapen; Marcel H M van Herwijnen; P A E L Schilderman; K R Smith; A E Aust; Maura Tomatis; Bice Fubini
In vitro effects of coal fly ashes: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells.
Inhalation toxicology 1999;11(12):1123-41.
1999: Paul J A Borm; B van Hartingsveld; P F Schins; Ernesto Alfaro-Moreno; G Cruz-Rico; I Rosas-Perez; Alvaro Roman Osornio-Vargas
Priming of cytokine release and increased levels of bactericidal permeability-increasing protein in the blood of animal facility workers.
International archives of occupational and environmental health 1999;72(5):323-9.
1999: Ad M Knaapen; Frank Seiler; P A E L Schilderman; P Nehls; Joachim Bruch; Roel P F Schins; Paul J A Borm
Neutrophils cause oxidative DNA damage in alveolar epithelial cells.
Free radical biology & medicine 1999;27(1-2):234-40.
1999: Herman-Jan Pennings; Paul J A Borm; C T Evelo; Emiel F M Wouters
Changes in levels of catalase and glutathione in erythrocytes of patients with stable asthma, treated with beclomethasone dipropionate.
The European respiratory journal 1999;13(6):1260-6.
1999: R P Schins; Paul J A Borm
Mechanisms and mediators in coal dust induced toxicity: a review.
The Annals of occupational hygiene 1999;43(1):7-33.
1998: R Zhai; M Jetten; R P Schins; H Franssen; Paul J A Borm
Polymorphisms in the promoter of the tumor necrosis factor-alpha gene in coal miners.
American journal of industrial medicine 1998;34(4):318-24.
1998: Jolanda van Golde; Paul J A Borm; M Wolfs; Willem-Jan M Gerver; carlos blanco
The effect of hyperoxia on embryonic and organ mass in the developing chick embryo.
Respiration physiology 1998;113(1):75-82.
1998: Ken Donaldson; Paul J A Borm
The quartz hazard: a variable entity.
The Annals of occupational hygiene 1998;42(5):287-94.
1998: Jolanda van Golde; Paul J A Borm; M C Wolfs; EH Rhijnsburger; carlos blanco
Induction of antioxidant enzyme activity by hyperoxia (60 % O2) in the developing chick embryo.
The Journal of physiology 1998;509 ( Pt 1)():289-96.
1998: Roger Godschalk; Lou M Maas; nico van zandwijk; Laura J van 't Veer; A Breedijk; Paul J A Borm; J Verhaert; Jos C S Kleinjans; Frederik J Van Schooten
Differences in aromatic-DNA adduct levels between alveolar macrophages and subpopulations of white blood cells from smokers.
Carcinogenesis 1998;19(5):819-25.
1998: S Keman; M Jetten; J Douwes; Paul J A Borm
Longitudinal changes in inflammatory markers in nasal lavage of cotton workers. Relation to endotoxin exposure and lung function changes.
International archives of occupational and environmental health 1998;71(2):131-7.
1997: Paul J A Borm
Toxicity and occupational health hazards of coal fly ash (CFA). A review of data and comparison to coal mine dust.
The Annals of occupational hygiene 1997;41(6):659-76.
1997: S Keman; B Willemse; David J Tollerud; Lucille Guevarra; R P Schins; Paul J A Borm
Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms.
American journal of industrial medicine 1997;32(6):670-3.
1997: Paul J A Borm; Ad M Knaapen; Roel P F Schins; Roger Godschalk; F J Schooten
Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells.
Environmental health perspectives 1997;105 Suppl 5():1089-93.
1996: Roel P F Schins; B van Hartingsveldt; Paul J A Borm
Ex vivo cytokine release from whole blood. A routine method for health effect screening.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(6):494-6.
1996: Paul J A Borm; K Driscoll
Particles, inflammation and respiratory tract carcinogenesis.
Toxicology letters 1996;88(1-3):109-13.
1996: S Keman; B Willemse; G J Wesseling; E Kusters; Paul J A Borm
A five year follow-up of lung function among chemical workers using flow-volume and impedance measurements.
The European respiratory journal 1996;9(10):2109-15.
1996: Paul J A Borm; Roel P F Schins; T J Derhaag; IJmert Kant; T H Jorna
Cross-shift changes in blood inflammatory markers occur in the absence of airway obstruction in workers exposed to grain dust.
Chest 1996;109(4):1078-85.
1995: Roel P F Schins; Paul J A Borm
Plasma levels of soluble tumour necrosis factor receptors are increased in coal miners with pneumoconiosis.
The European respiratory journal 1995;8(10):1658-63.
1995: Roel P F Schins; Paul J A Borm
Epidemiological evaluation of release of monocyte TNF-alpha as an exposure and effect marker in pneumoconiosis: a five year follow up study of coal workers.
Occupational and environmental medicine 1995;52(7):441-50.
1995: Beth A Hart; R M Prabhu; J D Eneman; C C Durieux-Lu; A M Janssen; Paul J A Borm
Oxidant resistance of cadmium-adapted human lung fibroblasts.
Toxicology 1995;98(1-3):1-13.
1995: Roel P F Schins; Rob Lamers; B Préat; Paul J A Borm
Evaluation of serum type III procollagen peptide as an exposure marker in retired coal workers.
International archives of occupational and environmental health 1995;66(6):413-9.
1995: Roel P F Schins; P A E L Schilderman; Paul J A Borm
Oxidative DNA damage in peripheral blood lymphocytes of coal workers.
International archives of occupational and environmental health 1995;67(3):153-7.
1994: YM Janssen; Nicholas H Heintz; J P Marsh; Paul J A Borm; Brooke T Mossman
Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.
American journal of respiratory cell and molecular biology 1994;11(5):522-30.
1994: T H Jorna; Paul J A Borm; J Valks; R Houba; Emiel F M Wouters
Respiratory symptoms and lung function in animal feed workers.
Chest 1994;106(4):1050-5.
1994: Paul J A Borm
Biological markers and occupational lung disease: mineral dust-induced respiratory disorders.
Experimental lung research 1994;20(5):457-70.
1994: Roel P F Schins; Paul J A Borm
Serum procollagen type III peptide in coal workers' pneumoconiosis: a five-year follow-up study.
Experimental lung research 1994;20(5):445-55.
1994: T H Jorna; Roel P F Schins; L Lenaerts; T J Derhaag; Emiel F M Wouters; Paul J A Borm
Airflow obstruction and monocyte TNF release in coal workers.
Experimental lung research 1994;20(5):421-31.
1994: YM Janssen; J P Marsh; M P Absher; Edward Gabrielson; Paul J A Borm; Kevin E Driscoll; Brooke T Mossman
Oxidant stress responses in human pleural mesothelial cells exposed to asbestos.
American journal of respiratory and critical care medicine 1994;149(3 Pt 1):795-802.
1994: YM Janssen; J P Marsh; Kevin E Driscoll; Paul J A Borm; Günter Oberdörster; Brooke T Mossman
Increased expression of manganese-containing superoxide dismutase in rat lungs after inhalation of inflammatory and fibrogenic minerals.
Free radical biology & medicine 1994;16(3):315-22.
1994: J P Marsh; Brooke T Mossman; Kevin E Driscoll; R F Schins; Paul J A Borm
Effects of Aramid, a high strength synthetic fiber, on respiratory cells in vitro.
Drug and chemical toxicology 1994;17(2):75-92.
1994: T H Jorna; Paul J A Borm; K D Koiter; Jos J M Slangen; P T Henderson; Emiel F M Wouters
Respiratory effects and serum type III procollagen in potato sorters exposed to diatomaceous earth.
International archives of occupational and environmental health 1994;66(4):217-22.
1993: YM Janssen; Bennett Van Houten; Paul J A Borm; Brooke T Mossman
Cell and tissue responses to oxidative damage.
Laboratory investigation; a journal of technical methods and pathology 1993;69(3):261-74.
1993: Paul J A Borm; P F Schins
Lymphocyte subsets in subjects exposed to asbestos: changes in circulating natural killer cells.
British journal of industrial medicine 1993;50(6):575.
1993: N G Palmen; Chris T A Evelo; Paul J A Borm; P T Henderson
Toxicokinetics of dimethylacetamide (DMAc) in rat isolated perfused liver.
Human & experimental toxicology 1993;12(2):127-33.
1992: Paul J A Borm; Roel P F Schins; YM Janssen; L Lenaerts
Molecular basis for differences in susceptibility to coal workers' pneumoconiosis.
Toxicology letters 1992;64-65 Spec No():767-72.
1992: YM Janssen; J P Marsh; M P Absher; David Hemenway; Pamela M Vacek; KO Leslie; Paul J A Borm; Brooke T Mossman
Expression of antioxidant enzymes in rat lungs after inhalation of asbestos or silica.
The Journal of biological chemistry 1992;267(15):10625-30.
1992: YM Janssen; J J Engelen; M S Giancola; Robert Low; Pamela M Vacek; Paul J A Borm
Serum type III procollagen N-terminal peptide in coal miners.
Experimental lung research 1992;18(1):1-8.
1992: IJmert Kant; L C de Jong; M van Rijssen-Moll; Paul J A Borm
A survey of static and dynamic work postures of operating room staff.
International archives of occupational and environmental health 1992;63(6):423-8.
1992: Sema Burgaz; Paul J A Borm; Frans J. Jongeneelen
Biological monitoring of exposure to bitumen fumes during road paving operations.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1992;15():278-81.
1991: A van Faassen; Paul J A Borm
Composition and health hazards of water-based construction paints: results from a survey in the Netherlands.
Environmental health perspectives 1991;92():147-54.
1991: C Sprong; YM Janssen; Paul J A Borm
The role of reactive oxygen species, cytokines and cytochrome P450 in pulmonary damage due to hyperoxia.
Medical hypotheses 1991;34(4):296-9.
1990: IJmert Kant; M van Rijssen-Moll; Paul J A Borm
Simulation of nitrous oxide concentrations in operating and recovery rooms.
The Annals of occupational hygiene 1990;34(6):575-83.
1990: Paul J A Borm; IJmert Kant; G Houben; M van Rijssen-Moll; P T Henderson
Monitoring of nitrous oxide in operating rooms: identification of sources and estimation of occupational exposure.
Journal of occupational medicine. : official publication of the Industrial Medical Association 1990;32(11):1112-6.
1990: Paul J A Borm; T H Jorna; P T Henderson
Setting acceptable exposure limits for toluene diisocyanate on the basis of different airway effects observed in animals.
Regulatory toxicology and pharmacology : RTP 1990;12(1):53-63.
1990: C J Doelman; Paul J A Borm; Aalt Bast
Plasticisers and bronchial hyperreactivity.
Lancet 1990;335(8691):725.
1990: J J Engelen; Paul J A Borm; M van Sprundel; L Leenaerts
Blood anti-oxidant parameters at different stages of pneumoconiosis in coal workers.
Environmental health perspectives 1990;84():165-72.
1990: IJmert Kant; J H Notermans; Paul J A Borm
Observations of working postures in garages using the Ovako Working posture Analysing System (OWAS) and consequent workload reduction recommendations.
Ergonomics 1990;33(2):209-20.
1990: Paul J A Borm; J M Meijers; Gerard M H Swaen
Molecular epidemiology of coal worker's pneumoconiosis: application to risk assessment of oxidant and monokine generation by mineral dusts.
Experimental lung research 1990;16(1):57-71.
1990: J M Meijers; Gerard M H Swaen; K van Vliet; Paul J A Borm
Epidemiologic studies of inorganic dust-related lung diseases in The Netherlands.
Experimental lung research 1990;16(1):15-23.
1990: YM Janssen; J P Marsh; M Absher; Paul J A Borm; Brooke T Mossman
Increases in endogenous antioxidant enzymes during asbestos inhalation in rats.
Free radical research communications 1990;11(1-3):53-8.
1989: Paul J A Borm; A Bast; O P Zuiderveld
In vitro effect of toluene diisocyanate on beta adrenergic and muscarinic receptor function in lung tissue of the rat.
British journal of industrial medicine 1989;46(1):56-9.
1988: Paul J A Borm; N Palmen; J J Engelen; W A Buurman
Spontaneous and stimulated release of tumor necrosis factor-alpha (TNF) from blood monocytes of miners with coal workers' pneumoconiosis.
The American review of respiratory disease 1988;138(6):1589-94.
1988: Paul J A Borm; C Van Vliet
Susceptibility in Parkinson's disease. 'Of mice and men'.
Medical hypotheses 1988;27(3):205-7.
1988: Paul J A Borm; B de Barbanson
Bias in biologic monitoring caused by concomitant medication.
Journal of occupational medicine. : official publication of the Industrial Medical Association 1988;30(3):214-23.
1987: Paul J A Borm; L de Jong; A Vliegen
Environmental and biological monitoring of workers occupationally exposed to dimethylacetamide.
Journal of occupational medicine. : official publication of the Industrial Medical Association 1987;29(11):898-903.
1987: Paul J A Borm; A Bast; Emiel F M Wouters; Jos J M Slangen; Gerard M H Swaen; T J De Boorder
Red blood cell anti-oxidant parameters in healthy elderly subjects versus silicosis patients.
Free radical research communications 1987;3(1-5):117-27.
1986: Paul J A Borm; A Bast; Emiel F M Wouters; Jos J M Slangen; Gerard M H Swaen; T de Boorder
Red blood cell anti-oxidant parameters in silicosis.
International archives of occupational and environmental health 1986;58(3):235-44.
1985: Paul J A Borm; A C Frankhuyzen-Sierevogel; E B Weller; J Noordhoek
Absorption and metabolism of hexamethylmelamine and pentamethylmelamine in rat everted perfused gut segments: correlation with in-vivo data.
The Journal of pharmacy and pharmacology 1985;37(9):629-36.
1984: Paul J A Borm; M J Mingels; A C Frankhuijzen-Sierevogel; M van Graft; A Hulshoff; J Noordhoek
Cellular and subcellular studies of the biotransformation of hexamethylmelamine in rat isolated hepatocytes and intestinal epithelial cells.
Cancer research 1984;44(7):2820-6.
1984: Andries Koster; Paul J A Borm; M R Dohmen; J Noordhoek
Localization of biotransformational enzymes along the crypt-villus axis of the rat intestine. Evaluation of two cell isolation procedures.
Cell biochemistry and function 1984;2(2):95-101.
1984: Paul J A Borm; M Kroon; J Noordhoek; K L Platt; F Oesch
Dose dependent activation of rat small intestinal monooxygenase-activity towards benzo(a)pyrene and 7-ethoxycoumarin after oral pretreatment with cimetidine.
Research communications in chemical pathology and pharmacology 1984;44(1):99-111.
1983: Paul J A Borm; Andries Koster; A Frankhuijzen-Sierevogel; J Noordhoek
Comparison of two cell isolation procedures to study in vitro intestinal wall biotransformation in control and 3-methyl-cholanthrene pretreated rats.
Cell biochemistry and function 1983;1(3):161-7.
1983: Paul J A Borm; A Frankhuijzen-Sierevogel; J Noordhoek
Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes. The effect of induction with 3-methylcholanthrene and inhibition with alpha-naphthoflavone.
Biochemical pharmacology 1983;32(10):1573-80.
1983: Jan T Keltjens; L Daniels; H G Jannsen; Paul J A Borm; Godfried D Vogels
A novel one-carbon carrier (carboxy-5,6,7,8-tetrahydromethanopterin) isolated from Methanobacterium thermoautotrophicum and derived from methanopterin.
European journal of biochemistry / FEBS 1983;130(3):545-52.
1980: R van Doorn; Paul J A Borm; C M Leijdekkers; P T Henderson; J Reuvers; T J van Bergen
Detection and identification of S-methylcysteine in urine of workers exposed to methyl chloride.
International archives of occupational and environmental health 1980;46(2):99-109.