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Denis deBlois

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Shant Der Sarkissian; Bun-Seng Tea; Rhian M Touyz; Denis deBlois; Taben M Hale
Role of angiotensin II type 2 receptor during regression of cardiac hypertrophy in spontaneously hypertensive rats.
Taben M Hale; Susan J Robertson; Kevin D Burns; Denis deBlois
Short-term ACE inhibition confers long-term protection against target organ damage.
Adil El Midaoui; Calin Lungu; Caroline Robillard; Hui Wang; Lingyun Wu; Denis deBlois; Réjean Couture
Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.

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All Publications

2013: Shant Der Sarkissian; Bun-Seng Tea; Rhian M Touyz; Denis deBlois; Taben M Hale
Role of angiotensin II type 2 receptor during regression of cardiac hypertrophy in spontaneously hypertensive rats.
Journal of the American Society of Hypertension : JASH 2013;7(2):118-27.
2012: Taben M Hale; Susan J Robertson; Kevin D Burns; Denis deBlois
Short-term ACE inhibition confers long-term protection against target organ damage.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(6):604-10.
2011: Adil El Midaoui; Calin Lungu; Caroline Robillard; Hui Wang; Lingyun Wu; Denis deBlois; Réjean Couture
Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.
Canadian journal of physiology and pharmacology 2011;89(10):743-51.
2011: Marielle Doyon; Taben Mary Hale; Julie-Emilie Huot-Marchand; Rong Wu; Jacques de Champlain; Denis deBlois
Does atorvastatin induce aortic smooth muscle cell apoptosis in vivo?
Vascular pharmacology 2011;54(1-2):5-12.
2010: Francois Marceau; Denis deBlois; Eric Petitclerc; Luc Levesque; G Drapeau; RM Audet; Denis Godin; JF Larrivée; Steeve Houle; Thierry Sabourin; Jean-Philippe Fortin; Guillaume Morissette; Lajos Gera; Marie-Thérèse Bawolak; Gérémy Abdull Koumbadinga; Johanne Bouthillier
Vascular smooth muscle contractility assays for inflammatory and immunological mediators.
International immunopharmacology 2010;10(11):1344-53.
2009: Julie Lemay; Taben M Hale; Denis deBlois
Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta.
European journal of pharmacology 2009;618(1-3):45-51.
2009: Viviane El-Helou; Cindy Proulx; Pauline Béguin; John Assimakopoulos; Hugues Gosselin; Robert Clement; Louis Villeneuve; Julie-Emilie Huot-Marchand; Denis deBlois; Claude Lajoie; Angelino Calderone
The cardiac neural stem cell phenotype is compromised in streptozotocin-induced diabetic cardiomyopathy.
Journal of cellular physiology 2009;220(2):440-9.
2009: Magalie Pilon; Rong Wu; Julie-Emilie Huot-Marchand; Denis deBlois; Jacques de Champlain; Réjean Couture
Effect of chronic inhibition of nitric oxide on hypertension, insulin resistance, and cardiovascular remodeling in glucose-fed rats.
Journal of cardiovascular pharmacology 2009;53(5):405-13.
2008: Xi Wang; Lawrence D Adams; Lil M Pabón; William Mahoney; Diane Beaudry; Jagadambika Gunaje; Randolph L Geary; Denis deBlois; Stephen M Schwartz
RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy.
Journal of molecular and cellular cardiology 2008;44(3):539-50.
2008: P-A Paquette; David Duguay; R El-Ayoubi; Ahmed Menaouar; Bogdan Alexandru Danalache; Jolanta Gutkowska; Denis deBlois; Suhayla Mukaddam-Daher
Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation.
British journal of pharmacology 2008;153(3):459-67.
2008: Claudia Jomphe; Mélanie Gabriac; Taben M Hale; Lucie Héroux; Louis-Eric Trudeau; Denis deBlois; Eulàlia Montell; Josep Vergés; Patrick Du Souich
Chondroitin sulfate inhibits the nuclear translocation of nuclear factor-kappaB in interleukin-1beta-stimulated chondrocytes.
Basic & clinical pharmacology & toxicology 2008;102(1):59-65.
2007: David Duguay; Denis deBlois
Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine.
British journal of pharmacology 2007;151(8):1315-23.
2007: David Duguay; Stéphanie Pesant; Christian Deschepper; Denis deBlois
Fibroblast apoptosis precedes cardiomyocyte mass reduction during left ventricular remodeling in hypertensive rats treated with amlodipine.
Journal of hypertension 2007;25(6):1291-9.
2007: Céline Bouvet; Wouter Peeters; Simon Moreau; Denis deBlois; Pierre Moreau
A new rat model of diabetic macrovascular complication.
Cardiovascular research 2007;73(3):504-11.
2005: Julie Dutil; Vasiliki Eliopoulos; Eve-Lyne Marchand; Alison M Devlin; Johanne Tremblay; Kalyani Prithiviraj; Pavel Hamet; Annik Migneault; Denis deBlois; Alan Y Deng
A quantitative trait locus for aortic smooth muscle cell number acting independently of blood pressure: implicating the angiotensin receptor AT1B gene as a candidate.
Physiological genomics 2005;21(3):362-9.
2005: Céline Bouvet; Liz-Ann Gilbert; Daphné Girardot; Denis deBlois; Pierre Moreau
Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition.
Hypertension 2005;45(3):432-7.
2005: Denis deBlois; Bun-Seng Tea; Diane Beaudry; Pavel Hamet
Regulation of therapeutic apoptosis: a potential target in controlling hypertensive organ damage.
Canadian journal of physiology and pharmacology 2005;83(1):29-41.
2004: Giuseppa Gennaro; Catherine Ménard; Sophie-Elise Michaud; Denis deBlois; Alain Rivard
Inhibition of vascular smooth muscle cell proliferation and neointimal formation in injured arteries by a novel, oral mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor.
Circulation 2004;110(21):3367-71.
2004: Mohamed Benderdour; Guy Charron; Blandine Comte; Riwa Ayoub; Diane Beaudry; Sylvain Foisy; Denis deBlois; Christine Des Rosiers
Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2122-31.
2004: Daphné Girardot; Bernard Jover; Jean-Pierre Moles; Denis deBlois; Pierre Moreau
Chronic nitric oxide synthase inhibition prevents new coronary capillary generation.
Journal of cardiovascular pharmacology 2004;44(3):322-8.
2004: Shant Der Sarkissian; Eve-Lyne Marchand; David Duguay; Denis deBlois
Synergistic interaction between enalapril, L-arginine and tetrahydrobiopterin in smooth muscle cell apoptosis and aortic remodeling induction in SHR.
British journal of pharmacology 2004;142(5):912-8.
2004: David Duguay; Shant Der Sarkissian; Rémi Kouz; Brice Ongali; Réjean Couture; Denis deBlois
Kinin B2 receptor is not involved in enalapril-induced apoptosis and regression of hypertrophy in spontaneously hypertensive rat aorta: possible role of B1 receptor.
British journal of pharmacology 2004;141(4):728-36.
2003: Mohamed Benderdour; Guy Charron; Denis deBlois; Blandine Comte; Christine Des Rosiers
Cardiac mitochondrial NADP+-isocitrate dehydrogenase is inactivated through 4-hydroxynonenal adduct formation: an event that precedes hypertrophy development.
The Journal of biological chemistry 2003;278(46):45154-9.
2003: Daphné Girardot; Bénédicte Demeilliers; Denis deBlois; Pierre Moreau
ERK1/2-mediated vasoconstriction normalizes wall stress in small mesenteric arteries during NOS inhibition in vivo.
Journal of cardiovascular pharmacology 2003;42(3):339-47.
2003: Eve-Lyne Marchand; Shant Der Sarkissian; Pavel Hamet; Denis deBlois
Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats.
Circulation research 2003;92(7):777-84.
2003: Sergei N Orlov; Dimitri Pchejetski; S D Sarkissian; VA Adarichev; Sebastien Taurin; Alexey V Pshezhetsky; Johanne Tremblay; Georgy V Maximov; Denis deBlois; Martin R Bennett; Pavel Hamet
[3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein.
Apoptosis : an international journal on programmed cell death 2003;8(2):199-208.
2003: Shant Der Sarkissian; Eve-Lyne Marchand; David Duguay; Pavel Hamet; Denis deBlois
Reversal of interstitial fibroblast hyperplasia via apoptosis in hypertensive rat heart with valsartan or enalapril.
Cardiovascular research 2003;57(3):775-83.
2003: Dimitri Pchejetski; Sebastien Taurin; Shant Der Sarkissian; Olga D Lopina; Alexey V Pshezhetsky; Johanne Tremblay; Denis deBlois; Pavel Hamet; Sergei N Orlov
Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio.
Biochemical and biophysical research communications 2003;301(3):735-44.
2002: Johanne Tremblay; Huifang Chen; Junzheng Peng; Jaroslav Kunes; Minh Diem Vu; Shant Der Sarkissian; Denis deBlois; Anthony E Bolton; Louis Gaboury; Vladimir Marshansky; Elodie GOUADON; Pavel Hamet
Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy.
Transplantation 2002;74(10):1425-33.
2002: Long-Qi Chen; CY Hu; Shant Der Sarkissian; Pasquale Ferraro; M Pera; Denis deBlois; Louis Gaboury; André Duranceau
Apoptosis in Barrett's oesophagus following antireflux surgery.
The British journal of surgery 2002;89(11):1444-9.
2002: Sergei N Orlov; Johanne Tremblay; Denis deBlois; Pavel Hamet
Genetics of programmed cell death and proliferation.
Seminars in nephrology 2002;22(2):161-71.
2002: Fabrice M A C Martens; Bénédicte Demeilliers; Daphné Girardot; Christine Daigle; Huy Hao Dao; Denis deBlois; Pierre Moreau
Vessel-specific stimulation of protein synthesis by nitric oxide synthase inhibition: role of extracellular signal-regulated kinases 1/2.
Hypertension 2002;39(1):16-21.
2001: Denis deBlois; S N Orlov; P Hamet
Apoptosis in cardiovascular remodeling--effect of medication.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(6):539-45.
2001: Huy Hao Dao; Julie Lemay; Jacques de Champlain; Denis deBlois; Pierre Moreau
Norepinephrine-induced aortic hyperplasia and extracellular matrix deposition are endothelin-dependent.
Journal of hypertension 2001;19(11):1965-73.
2001: Nathalie Thorin-Trescases; Denis deBlois; Pavel Hamet
Evidence of an altered in vivo vascular cell turnover in spontaneously hypertensive rats and its modulation by long-term antihypertensive treatment.
Journal of cardiovascular pharmacology 2001;38(5):764-74.
2001: Julie Lemay; Bun-Seng Tea; Pavel Hamet; Denis deBlois
Regression of neointimal lesions in the carotid artery of nifedipine-treated SHR and WKY rats: possible role of apoptosis.
Journal of vascular research 2001;38(5):462-70.
2001: Nathalie Thorin-Trescases; Sergei N Orlov; Sebastien Taurin; Nickolai O Dulin; Bruce G Allen; Denis deBlois; Johanne Tremblay; Alexey V Pshezhetsky; Pavel Hamet
Antiproliferative effect of brief exposure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A.
Canadian journal of physiology and pharmacology 2001;79(6):471-80.
2001: Pavel Hamet; Denis deBlois
Endothelial and myocyte apoptosis--role of angiotensin II.
The Canadian journal of cardiology 2001;17 Suppl A():26A-8A.
2001: Pavel Hamet; Nathalie Thorin-Trescases; Pierre Moreau; Pierre Dumas; Bun-Seng Tea; Denis deBlois; Vladimír Kren; Michal Pravenec; Jaroslav Kunes; Y Sun; Johanne Tremblay
Workshop: excess growth and apoptosis: is hypertension a case of accelerated aging of cardiovascular cells?
Hypertension 2001;37(2 Pt 2):760-6.
2001: Denis deBlois; R A Horlick
Endotoxin sensitization to kinin B(1) receptor agonist in a non-human primate model: haemodynamic and pro-inflammatory effects.
British journal of pharmacology 2001;132(1):327-35.
2000: Bun-Seng Tea; Shant Der Sarkissian; R M Touyz; Pavel Hamet; Denis deBlois
Proapoptotic and growth-inhibitory role of angiotensin II type 2 receptor in vascular smooth muscle cells of spontaneously hypertensive rats in vivo.
Hypertension 2000;35(5):1069-73.
2000: Julie Lemay; Y Hou; Denis deBlois
Evidence that nitric oxide regulates AT1-receptor agonist and antagonist efficacy in rat injured carotid artery.
Journal of cardiovascular pharmacology 2000;35(5):693-9.
2000: Julie Lemay; Y Hou; J Tremblay; Denis deBlois
Angiotensin I-converting enzyme activity and vascular sensitivity to angiotensin I in rat injured carotid artery.
European journal of pharmacology 2000;394(2-3):301-9.
2000: Julie Lemay; Pavel Hamet; Denis deBlois
Losartan-induced apoptosis as a novel mechanism for the prevention of vascular lesion formation after injury.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2000;1(1):46-50.
1999: Bun-Seng Tea; T V Dam; Pierre Moreau; Pavel Hamet; Denis deBlois
Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity.
Hypertension 1999;34(2):229-35.
1998: PJ Silver; J P Moreau; EM Denholm; Y Q Lin; L Nguyen; C Bennett; A Recktenwald; Denis deBlois; S Baker; S Ranger
Heparinase III limits rat arterial smooth muscle cell proliferation in vitro and in vivo.
European journal of pharmacology 1998;351(1):79-83.
1997: M R Bennett; V Lindner; Denis deBlois; Michael A Reidy; Stephen M Schwartz
Effect of phosphorothioated oligonucleotides on neointima formation in the rat carotid artery. Dissecting the mechanism of action.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2326-32.
1997: Denis deBlois; Bun-Seng Tea; V D Than; Johanne Tremblay; Pavel Hamet
Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats.
Hypertension 1997;29(1 Pt 2):340-9.
1997: Lucy Liaw; DM Lombardi; M M Almeida; Stephen M Schwartz; Denis deBlois; Cecilia M Giachelli
Neutralizing antibodies directed against osteopontin inhibit rat carotid neointimal thickening after endothelial denudation.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(1):188-93.
1996: Denis deBlois; DM Lombardi; Enming Joseph Su; Alexander W Clowes; Stephen M Schwartz; Cecilia M Giachelli
Angiotensin II induction of osteopontin expression and DNA replication in rat arteries.
Hypertension 1996;28(6):1055-63.
1996: Denis deBlois; M Viswanathan; Enming Joseph Su; Alexander W Clowes; J M Saavedra; Stephen M Schwartz
Smooth muscle DNA replication in response to angiotensin II is regulated differently in the neointima and media at different times after balloon injury in the rat carotid artery. Role of AT1 receptor expression.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(9):1130-7.
1996: Denis deBlois; Stephen M Schwartz; E M van Kleef; Enming Joseph Su; Karen A Griffin; Anil K Bidani; Mat J A P Daemen; DM Lombardi
Chronic alpha 1-adrenoreceptor stimulation increases DNA synthesis in rat arterial wall. Modulation of responsiveness after vascular injury.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(9):1122-9.
1996: Pavel Hamet; Denis deBlois; T V Dam; L Richard; E Teiger; Bun-Seng Tea; Sergei N Orlov; Johanne Tremblay
Apoptosis and vascular wall remodeling in hypertension.
Canadian journal of physiology and pharmacology 1996;74(7):850-61.
1995: Stephen M Schwartz; Denis deBlois; Edward O'Brien
The intima. Soil for atherosclerosis and restenosis.
Circulation research 1995;77(3):445-65.
1995: C Smith-Hanrahan; Denis deBlois
Postpartum early discharge: impact on maternal fatigue and functional ability.
Clinical nursing research 1995;4(1):50-66.
1992: Eric Petitclerc; S Abel; Denis deBlois; Patrice E Poubelle; Francois Marceau
Effects of interleukin-1 receptor antagonist on three types of responses to interleukin-1 in rabbit isolated blood vessels.
Journal of cardiovascular pharmacology 1992;19(5):821-9.
1992: Denis deBlois; G Drapeau; Eric Petitclerc; Francois Marceau
Synergism between the contractile effect of epidermal growth factor and that of des-Arg9-bradykinin or of alpha-thrombin in rabbit aortic rings.
British journal of pharmacology 1992;105(4):959-67.
1991: G Drapeau; Denis deBlois; Francois Marceau
Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins.
The Journal of pharmacology and experimental therapeutics 1991;259(3):997-1003.
1991: Francois Marceau; Eric Petitclerc; Denis deBlois; P Pradelles; Patrice E Poubelle
Human interleukin-1 induces a rapid relaxation of the rabbit isolated mesenteric artery.
British journal of pharmacology 1991;103(2):1367-72.
1991: Denis deBlois; Johanne Bouthillier; Francois Marceau
Pulse exposure to protein synthesis inhibitors enhances vascular responses to des-Arg9-bradykinin: possible role of interleukin-1.
British journal of pharmacology 1991;103(1):1057-66.
1990: Francois Marceau; Denis deBlois; C Laplante; Eric Petitclerc; G Pelletier; J H Grose; T E Hugli
Contractile effect of the chemotactic factors f-Met-Leu-Phe and C5a on the human isolated umbilical artery. Role of cyclooxygenase products and tissue macrophages.
Circulation research 1990;67(5):1059-70.
1990: Denis deBlois; Johanne Bouthillier; Francois Marceau
Bacitracin U.S.P. contains a factor that stimulates receptors for 5-hydroxytryptamine on rabbit aortic strips.
Life sciences 1990;47(19):PL103-8.
1989: Denis deBlois; Johanne Bouthillier; Francois Marceau
Pharmacological modulation of the up-regulated responses to des-Arg9-bradykinin in vivo and in vitro.
Immunopharmacology 1989;17(3):187-98.
1988: Denis deBlois; Johanne Bouthillier; Francois Marceau
Effect of glucocorticoids, monokines and growth factors on the spontaneously developing responses of the rabbit isolated aorta to des-Arg9-bradykinin.
British journal of pharmacology 1988;93(4):969-77.
1987: Denis deBlois; Francois Marceau
The ability of des-Arg9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation.
European journal of pharmacology 1987;142(1):141-4.
1987: Johanne Bouthillier; Denis deBlois; Francois Marceau
Studies on the induction of pharmacological responses to des-Arg9-bradykinin in vitro and in vivo.
British journal of pharmacology 1987;92(2):257-64.