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Nikos Karamanos

Research Profile

Chemicals & Drugs

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Staphylococcus epidermidis

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TOP 3
P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease.
Ch Gialeli; Dimitris Kletsas; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Nikos Karamanos; Robert J Linhardt
Special Issue: Proteoglycans: signaling, targeting and therapeutics: Introduction.

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All Publications

2013: P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease.
Biochimica et biophysica acta 2013;1830(6):3625-34.
2013: Ch Gialeli; Dimitris Kletsas; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Investigational new drugs 2013;31(3):516-24.
2013: Nikos Karamanos; Robert J Linhardt
Special Issue: Proteoglycans: signaling, targeting and therapeutics: Introduction.
The FEBS journal 2013;280(10):2119.
2013: Evgenia G Karousou; Paola Moretto; Francesco Pallotti; Maria Luisa D'Angelo; Giancarlo De Luca; Fabio Ghezzi; Nikos Karamanos; Luigi Raio; Xanthi Stachtea; Davide Vigetti; Manuela Viola; Alberto Passi
New insights into the pathobiology of Down syndrome - hyaluronan synthase-2 overexpression is regulated by collagen VI α2 chain.
The FEBS journal 2013;280(10):2418-30.
2013: Antonis Skliris; Alexios Aletras; Nikos Karamanos; Vassiliki T Labropoulou; Dionysios J Papachristou; Achilleas D Theocharis
Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases.
The FEBS journal 2013;280(10):2342-52.
2013: Christina J Malavaki; Andreas E Roussidis; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Chrisostomi Gialeli; Dimitris Kletsas; Nikos Karamanos
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.
The FEBS journal 2013;280(10):2477-89.
2013: Anastasios I Tsonis; George N Tzanakakis; Zoi Piperigkou; Spyros S Skandalis; Achilleas D Theocharis; Nikolaos Afratis; Maria-Ioanna Ellina; Chrisostomi Gialeli; Nikos Karamanos
Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells.
The FEBS journal 2013;280(10):2248-59.
2013: Maria Mytilinaiou; Dragana Nikitovic; Kallirroi Voudouri; Artan Bano; Aikaterini Berdiaki; Alexandra Kalogeraki; Nikos Karamanos; George N Tzanakakis
Syndecan-2 is a key regulator of transforming growth factor beta 2/Smad2-mediated adhesion in fibrosarcoma cells.
IUBMB life 2013;65(2):134-43.
2012: P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; A I Tsonis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid.
Biochimica et biophysica acta 2012;1820(12):1926-39.
2012: E Milia-Argeiti; SAMIA MOURAH; P Fenichel; E Huet; Nikos Karamanos; V T Labropoulou; S Menashi; Achilleas D Theocharis
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
International journal of andrology 2012;35(6):835-44.
2012: Dragana Nikitovic; John Aggelidakis; Renato V Iozzo; Nikos Karamanos; Marian F Young; George N Tzanakakis
The biology of small leucine-rich proteoglycans in bone pathophysiology.
The Journal of biological chemistry 2012;287(41):33926-33.
2012: Paul Zarogoulidis; Chrisostomi Giraleli; Nikos Karamanos
Inhaled chemotherapy in lung cancer: safety concerns of nanocomplexes delivered.
Therapeutic delivery 2012;3(9):1021-3.
2012: P Zarogoulidis; Ekaterini Chatzaki; Grammati Galaktidou; E P Goldberg; W Hohenforst-Schmidt; Nikos Karamanos; Theodore Kontakiotis; Kostas Zarogoulidis
Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review.
Cancer gene therapy 2012;19(9):593-600.
2012: Spyros S Skandalis; Achilleas D Theocharis; George N Tzanakakis; N Afratis; A J Aletras; C Gialeli; Nikos Karamanos
Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules.
Current molecular medicine 2012;12(8):1068-82.
2012: Aleksandra S Kristo; Fotini N Lamari; Christina J Malavaki; Nikos Karamanos; Dorothy Klimis-Zacas
Wild blueberry (V. angustifolium)-enriched diets alter aortic glycosaminoglycan profile in the spontaneously hypertensive rat.
The Journal of nutritional biochemistry 2012;23(8):961-5.
2012: Paul Zarogoulidis; Vasiliki Zarogoulidou; Athanasios Zisimopoulos; Ellada Eleftheriadou; Nikos Karamanos; Theodore Kontakiotis; Helliel Lithoxopoulou; Maria Mabroudi; Iordanis Sapardanis; George A Zachariadis; Kostas Zarogoulidis
Feasibility and effectiveness of inhaled carboplatin in NSCLC patients.
Investigational new drugs 2012;30(4):1628-40.
2012: Emmanouil G Barbounis; Nikos Karamanos; Aikaterini Kokkinaki; Andreas Tsakalof; Athanasios Alegakis; Manolis N Tzatzarakis; Aristidis M Tsatsakis
Assessment of PCBs exposure in human hair using double focusing high resolution mass spectrometry and single quadrupole mass spectrometry.
Toxicology letters 2012;210(2):225-31.
2012: Nikos Afratis; Chrisostomi Gialeli; Evgenia Karousou; Dragana Nikitovic; Mauro S Pavão; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Glycosaminoglycans: key players in cancer cell biology and treatment.
The FEBS journal 2012;279(7):1177-97.
2012: Nikos Karamanos; George N Tzanakakis
Glycosaminoglycans: from "cellular glue" to novel therapeutical agents.
Current opinion in pharmacology 2012;12(2):220-2.
2012: Paul Zarogouldis; Kalliopi Domvri; Eugene P Goldberg; Wolfgang Hohenforst-Schimdt; Haidong Huang; Nikos Karamanos; Konstantinos Porpodis; Konstantinos Zarogoulidis
Vectors for inhaled gene therapy in lung cancer. Application for nano oncology and safety of bio nanotechnology.
International journal of molecular sciences 2012;13(9):10828-62.
2012: Dragana Nikitovic; A Tsatsakis; John Tsiaoussis; G Chatzinikolaou; Nikos Karamanos; George N Tzanakakis
Insights into targeting colon cancer cell fate at the level of proteoglycans / glycosaminoglycans.
Current medicinal chemistry 2012;19(25):4247-58.
2012: Paul Zarogoulidis; Ekaterini Chatzaki; Kalliopi Domvri; Eugene P Goldberg; Wolfgang Hohenforst-Schmidt; Nikos Karamanos; Konstantinos Porpodis; Kostas Zarogoulidis
Inhaled chemotherapy in lung cancer: future concept of nanomedicine.
International journal of nanomedicine 2012;7():1551-72.
2012: Anastasia I Spiliopoulou; Thomas S Wilkinson; Angharad P Davies; George Dimitracopoulos; Llinos G Harris; Nikos Karamanos; Fevronia Kolonitsiou; Maria I Krevvata; Dietrich Mack; Evangelos D Anastassiou
An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis.
BMC microbiology 2012;12():76.
2011: Georgia Chalkiadaki; Nikos Karamanos; Pavlos Katonis; Ioanna Kotsikogianni; Dragana Nikitovic; Aristidis Tsatsakis; Aikaterini Berdiaki; George N Tzanakakis
Low molecular weight heparin inhibits melanoma cell adhesion and migration through a PKCa/JNK signaling pathway inducing actin cytoskeleton changes.
Cancer letters 2011;312(2):235-44.
2011: Katerina Kouvidi; Dragana Nikitovic; Nikos Afratis; Aikaterini Berdiaki; Vincent C Hascall; Nikos Karamanos; Pavlos Katonis; George N Tzanakakis
Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.
The Journal of biological chemistry 2011;286(44):38509-20.
2011: Georgios A Datsis; Nikos Karamanos; Pavlos Katonis; Maria Mytilineou; Dragana Nikitovic; Aikaterini Berdiaki; George N Tzanakakis
Parathyroid hormone affects the fibroblast growth factor-proteoglycan signaling axis to regulate osteosarcoma cell migration.
The FEBS journal 2011;278(19):3782-92.
2011: D Karangelis; T Koufakis; Georgios I Tagarakis; Filippos Triposkiadis; Nikolaos B Tsilimingas; A Asimakopoulou; Ioannis Kanakis; Nikos Karamanos
Monitoring serum chondroitin sulfate levels in patients submitted to coronary artery bypass surgery.
Biomedical chromatography : BMC 2011;25(7):748-50.
2011: Dragana Nikitovic; Georgia Chalkiadaki; Aikaterini Berdiaki; John Aggelidakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity.
The international journal of biochemistry & cell biology 2011;43(6):928-35.
2011: Maria I Krevvata; Anastasia Spiliopoulou; Evangelos D Anastassiou; Nikos Karamanos; Fevronia Kolonitsiou
Adherence of Staphylococcus epidermidis to human endothelial cells is associated with a polysaccharidic component of its extracellular mucous layer.
Connective tissue research 2011;52(3):183-9.
2011: Suniti Misra; Spyros S Skandalis; Vincent C Hascall; Paraskevi Heldin; Nikos Karamanos; Roger R Markwald; Shibnath Ghatak
Hyaluronan-CD44 interactions as potential targets for cancer therapy.
The FEBS journal 2011;278(9):1429-43.
2011: Vincent Hascall; Nikos Karamanos
Regulatory roles of hyaluronan in health and disease.
The FEBS journal 2011;278(9):1411.
2011: Maria I Krevvata; Nikos Afratis; Anastasia Spiliopoulou; Christina J Malavaki; Fevronia Kolonitsiou; Evangelos Anastassiou; Nikos Karamanos
A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis.
Biomedical chromatography : BMC 2011;25(5):531-4.
2011: Georgia Chalkiadaki; Dragana Nikitovic; Aikaterini Berdiaki; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Heparin plays a key regulatory role via a p53/FAK-dependent signaling in melanoma cell adhesion and migration.
IUBMB life 2011;63(2):109-19.
2011: George E Magoulas; Stavros E Bariamis; Constantinos M Athanassopoulos; Anastasios Haskopoulos; Petros G Dedes; Marios G Krokidis; Nikos Karamanos; Dimitris Kletsas; Dionissios Papaioannou; George Maroulis
Syntheses, antiproliferative activity and theoretical characterization of acitretin-type retinoids with changes in the lipophilic part.
European journal of medicinal chemistry 2011;46(2):721-37.
2011: Spyros S Skandalis; Katalin Dobra; Haralabos P Kalofonos; Nikos Karamanos; Vassiliki T Labropoulou; Eleni Likaki-Karatza; Panagiota Ravazoula; Achilleas D Theocharis
Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas.
BMC cancer 2011;11():314.
2011: V T Labropoulou; Achilleas D Theocharis; A Symeonidis; Spyros S Skandalis; Nikos Karamanos; Haralabos P Kalofonos
Pathophysiology and pharmacological targeting of tumor-induced bone disease: current status and emerging therapeutic interventions.
Current medicinal chemistry 2011;18(11):1584-98.
2011: Hideaki Nagase; Nikos Karamanos
Metalloproteinases in health and disease: challenges and the future prospects.
The FEBS journal 2011;278(1):1.
2011: Christina J Malavaki; Achilleas D Theocharis; Fotini N Lamari; Ioannis Kanakis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization.
Biomedical chromatography : BMC 2011;25(1-2):11-20.
2011: Chrisostomi Gialeli; Achilleas D Theocharis; Nikos Karamanos
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting.
The FEBS journal 2011;278(1):16-27.
2011: Dimitra G Chryssanthi; Petros G Dedes; Nikos Karamanos; Paul Cordopatis; Fotini N Lamari
Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.
Planta medica 2011;77(2):146-51.
2010: Achilleas D Theocharis; Spyros S Skandalis; George N Tzanakakis; Nikos Karamanos
Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.
The FEBS journal 2010;277(19):3904-23.
2010: Renato V Iozzo; Nikos Karamanos
Proteoglycans in health and disease: emerging concepts and future directions.
The FEBS journal 2010;277(19):3863.
2010: Constantinos D Georgakopoulos; Fotini N Lamari; Ioanna N Karathanasopoulou; Vassiliki S Gartaganis; Nikolaos M Pharmakakis; Nikos Karamanos
Tear analysis of ascorbic acid, uric acid and malondialdehyde with capillary electrophoresis.
Biomedical chromatography : BMC 2010;24(8):852-7.
2010: Aikaterini Berdiaki; Georgios A Datsis; Dragana Nikitovic; Aristidis Tsatsakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Parathyroid hormone (PTH) peptides through the regulation of hyaluronan metabolism affect osteosarcoma cell migration.
IUBMB life 2010;62(5):377-86.
2010: G Chatzinikolaou; Dragana Nikitovic; A Berdiaki; Alexandros Zafiropoulos; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Heparin regulates colon cancer cell growth through p38 mitogen-activated protein kinase signalling.
Cell proliferation 2010;43(1):9-18.
2010: D E Karangelis; Ioannis Kanakis; A P Asimakopoulou; E Karousou; A Passi; Achilleas D Theocharis; F Triposkiadis; N B Tsilimingas; Nikos Karamanos
Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan.
Current medicinal chemistry 2010;17(33):4018-26.
2010: S K Karadimas; C H Gialeli; G Klironomos; G N Tzanakakis; Elias Panagiotopoulos; Nikos Karamanos; G Gatzounis
The role of oligodendrocytes in the molecular pathobiology and potential molecular treatment of cervical spondylotic myelopathy.
Current medicinal chemistry 2010;17(11):1048-58.
2010: G Anastassopoulos; Sofia D Panteliou; G Christopoulou; A Stavropoulou; Elias Panagiotopoulos; G Lyritis; Lubna Khaldi; John Varakis; Nikos Karamanos
Vibrational bone characteristics versus bone density for the assessment of osteoporosis in ovariectomized rats.
Journal of medical engineering & technology 2010;34(1):35-42.
2009: Aikaterini Berdiaki; Dragana Nikitovic; Aristidis M Tsatsakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.
Biochimica et biophysica acta 2009;1790(10):1258-65.
2009: Kostas Zarogoulidis; Eufimia Boutsikou; Pavlos Zarogoulidis; Ellada Eleftheriadou; Theodore Kontakiotis; Hellie Lithoxopoulou; George Tzanakakis; Ioannis Kanakis; Nikos Karamanos
The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis.
International journal of cancer. Journal international du cancer 2009;125(7):1705-9.
2009: Xanthi Stachtea; Nikos Karamanos; Nikolaos Klouras
Enhanced antitumour activity of cyclopendadienyl-substituted metallocene dihalides in human breast and colon cancer cells.
Anticancer research 2009;29(8):3227-31.
2009: Georgia Chalkiadaki; Dragana Nikitovic; Aikaterini Berdiaki; Maria Sifaki; Konstantin Krasagakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism.
The international journal of biochemistry & cell biology 2009;41(6):1323-31.
2009: Vassiliki M Mania; Alkiviadis G Kallivokas; Christina Malavaki; Athanasia P Asimakopoulou; John Kanakis; Achilleas D Theocharis; George Klironomos; George Gatzounis; Athanasia Mouzaki; Elias Panagiotopoulos; Nikos Karamanos
A comparative biochemical analysis of glycosaminoglycans and proteoglycans in human orthotopic and heterotopic bone.
IUBMB life 2009;61(4):447-52.
2009: Ch Gialeli; Dimitris Kletsas; D Mavroudis; Haralabos P Kalofonos; George N Tzanakakis; Nikos Karamanos
Targeting epidermal growth factor receptor in solid tumors: critical evaluation of the biological importance of therapeutic monoclonal antibodies.
Current medicinal chemistry 2009;16(29):3797-804.
2009: Nikolaos Charokopos; Nikolaos Apostolopoulos; Maria Kalapodi; Michael Leotsinidis; Nikos Karamanos; Athanasia Mouzaki
Bronchial asthma, chronic obstructive pulmonary disease and NF-kappaB.
Current medicinal chemistry 2009;16(7):867-83.
2008: Dragana Nikitovic; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Lumican, a small leucine-rich proteoglycan.
IUBMB life 2008;60(12):818-23.
2008: Olga Ch Kousidou; Aikaterini Berdiaki; Dimitris Kletsas; Alexandros Zafiropoulos; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Estradiol-estrogen receptor: a key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells.
Molecular oncology 2008;2(3):223-32.
2008: Virginia Kilia; Spyros S Skandalis; Achilleas D Theocharis; Dimitrios A Theocharis; Nikos Karamanos; Nickoletta Papageorgakopoulou
Glycosaminoglycan in cerebrum, cerebellum and brainstem of young sheep brain with particular reference to compositional and structural variations of chondroitin-dermatan sulfate and hyaluronan.
Biomedical chromatography : BMC 2008;22(9):931-8.
2008: Athanasia P Asimakopoulou; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents.
In vivo (Athens, Greece) 2008;22(3):385-9.
2008: Alexandros Zafiropoulos; Dragana Nikitovic; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Decorin-induced growth inhibition is overcome through protracted expression and activation of epidermal growth factor receptors in osteosarcoma cells.
Molecular cancer research : MCR 2008;6(5):785-94.
2008: Vassiliki Gioni; Theodoros Karampinas; Gerassimos Voutsinas; Andreas E Roussidis; Savvas Papadopoulos; Nikos Karamanos; Dimitris Kletsas
Imatinib mesylate inhibits proliferation and exerts an antifibrotic effect in human breast stroma fibroblasts.
Molecular cancer research : MCR 2008;6(5):706-14.
2008: Georgia Chatzinikolaou; Dragana Nikitovic; Athanasia Asimakopoulou; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Heparin--a unique stimulator of human colon cancer cells' growth.
IUBMB life 2008;60(5):333-40.
2008: Evangelia Papadimitriou; George Koliakos; Nikos Karamanos
Biochemistry and molecular biology in Greece: history and perspectives.
IUBMB life 2008;60(5):250-3.
2008: E Fthenou; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate prevents platelet derived growth factor-mediated phosphorylation of PDGF-Rbeta in normal human fibroblasts severely impairing mitogenic responses.
Journal of cellular biochemistry 2008;103(6):1866-76.
2008: F Kottakis; Fotini N Lamari; Ch Matragkou; George A Zachariadis; Nikos Karamanos; Theodora Choli-Papadopoulou
Arabino-galactan proteins from Pistacia lentiscus var. chia: isolation, characterization and biological function.
Amino acids 2008;34(3):413-20.
2008: Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; Andreas Roussidis; George N Tzanakakis; Nikos Karamanos
Design, synthesis and cell growth inhibitory activity of a series of novel aminosubstituted xantheno[1,2-d]imidazoles in breast cancer cells.
Bioorganic & medicinal chemistry 2008;16(6):3445-55.
2008: Christina J Malavaki; Athanasia P Asimakopoulou; Fotini N Lamari; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Capillary electrophoresis for the quality control of chondroitin sulfates in raw materials and formulations.
Analytical biochemistry 2008;374(1):213-20.
2008: A Berdiaki; Alexandros Zafiropoulos; E Fthenou; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Regulation of hyaluronan and versican deposition by growth factors in fibrosarcoma cell lines.
Biochimica et biophysica acta 2008;1780(2):194-202.
2008: Dragana Nikitovic; Katerina Berdiaki; Georgia Chalkiadaki; Nikos Karamanos; George N Tzanakakis
The role of SLRP-proteoglycans in osteosarcoma pathogenesis.
Connective tissue research 2008;49(3):235-8.
2008: Xanthi N Stahtea; Olga Ch Kousidou; Andreas E Roussidis; George N Tzanakakis; Nikos Karamanos
Small tyrosine kinase inhibitors as key molecules in the expression of metalloproteinases by solid tumors.
Connective tissue research 2008;49(3):211-4.
2008: Christina Malavaki; Shuji Mizumoto; Nikos Karamanos; Kazuyuki Sugahara
Recent advances in the structural study of functional chondroitin sulfate and dermatan sulfate in health and disease.
Connective tissue research 2008;49(3):133-9.
2008: Dimitrios A Theocharis; Spyros S Skandalis; Argiris V Noulas; Nickoletta Papageorgakopoulou; Achilleas D Theocharis; Nikos Karamanos
Hyaluronan and chondroitin sulfate proteoglycans in the supramolecular organization of the mammalian vitreous body.
Connective tissue research 2008;49(3):124-8.
2008: Dragana Nikitovic; Aikaterini Berdiaki; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells.
The FEBS journal 2008;275(2):350-61.
2008: Dragana Nikitovic; M Assouti; M Sifaki; Pavlos Katonis; Konstantin Krasagakis; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines.
The international journal of biochemistry & cell biology 2008;40(1):72-83.
2007: Xanthi N Stahtea; Andreas E Roussidis; Ioannis Kanakis; George N Tzanakakis; george chalkiadakis; Dimitris Mavroudis; Dimitris Kletsas; Nikos Karamanos
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation.
International journal of cancer. Journal international du cancer 2007;121(12):2808-14.
2007: G Chatzinikolaou; Dragana Nikitovic; Efstathios N Stathopoulos; G A Velegrakis; Nikos Karamanos; George N Tzanakakis
Protein tyrosine kinase and estrogen receptor-dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines.
Anticancer research 2007;27(6B):4101-6.
2007: Vasiliki Giannouli; Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Design, synthesis, and evaluation of the antiproliferative activity of a series of novel fused xanthenone aminoderivatives in human breast cancer cells.
Journal of medicinal chemistry 2007;50(7):1716-9.
2007: George N Tzanakakis; Dragana Nikitovic; Pavlos Katonis; Ioannis Kanakis; Nikos Karamanos
Expression and distribution of N-acetyl and N-glycolylneuraminic acids in secreted and cell-associated glycoconjugates by two human osteosarcoma cell lines.
Biomedical chromatography : BMC 2007;21(4):406-9.
2007: George Kolokythas; Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells.
European journal of medicinal chemistry 2007;42(3):307-19.
2007: Dimitra G Chryssanthi; Fotini N Lamari; Gregoris Iatrou; Adamantia Pylara; Nikos Karamanos; Paul Cordopatis
Inhibition of breast cancer cell proliferation by style constituents of different Crocus species.
Anticancer research 2007;27(1A):357-62.
2007: Andreas E Roussidis; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer.
Current medicinal chemistry 2007;14(7):735-43.
2006: V T Labropoulou; Achilleas D Theocharis; Panagiota Ravazoula; Petros Perimenis; Anders Hjerpe; Nikos Karamanos; Haralabos P Kalofonos
Versican but not decorin accumulation is related to metastatic potential and neovascularization in testicular germ cell tumours.
Histopathology 2006;49(6):582-93.
2006: Achilleas D Theocharis; Carina Seidel; Magne Borset; Katalin Dobra; Vadim Baykov; Vassiliki Labropoulou; Ioannis Kanakis; Evangelos Dalas; Nikos Karamanos; Anders Sundan; Anders Hjerpe
Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro.
The Journal of biological chemistry 2006;281(46):35116-28.
2006: Fotini N Lamari; Aikaterini A Zompra; Evangelia Pateraki; Olga C Kousidou; Vassiliki Magafa; Nikos Karamanos; Paul Cordopatis
Gonadotropin-releasing hormone analogues alter gene expression of metalloproteinases and their tissue inhibitors in human breast cancer epithelial cells.
Anticancer research 2006;26(6B):4615-21.
2006: M Sifaki; M Assouti; Dragana Nikitovic; Konstantin Krasagakis; Nikos Karamanos; George N Tzanakakis
Lumican, a small leucine-rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes.
IUBMB life 2006;58(10):606-10.
2006: Kalea Anastasia; Fotini N Lamari; Achilleas D Theocharis; Dale A Schuschke; Nikos Karamanos; Dorothy Klimis-Zacas
Dietary manganese affects the concentration, composition and sulfation pattern of heparan sulfate glycosaminoglycans in Sprague-Dawley rat aorta.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2006;19(5):535-46.
2006: K V Kakavas; Argiris V Noulas; Ioannis Kanakis; Sophia Bonanou; Nikos Karamanos
Identification of the commonest cystic fibrosis transmembrane regulator gene DeltaF508 mutation: evaluation of PCR--single-strand conformational polymorphism and polyacrylamide gel electrophoresis.
Biomedical chromatography : BMC 2006;20(10):1120-5.
2006: Ioannis K Petropoulos; Chrysoula V Vantzou; Fotini N Lamari; Nikos Karamanos; Evangelos D Anastassiou; Nikolaos M Pharmakakis
Expression of TNF-alpha, IL-1beta, and IFN-gamma in Staphylococcus epidermidis slime-positive experimental endophthalmitis is closely related to clinical inflammatory scores.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2006;244(10):1322-8.
2006: Spyros S Skandalis; Achilleas D Theocharis; Demitrios H Vynios; Nickoletta Papageorgakopoulou; Anders Hjerpe; Nikos Karamanos; Dimitrios A Theocharis
Cartilage aggrecan undergoes significant compositional and structural alterations during laryngeal cancer.
Biochimica et biophysica acta 2006;1760(7):1046-53.
2006: G E Christopoulou; A Stavropoulou; G Anastassopoulos; Sofia D Panteliou; E Papadaki; Nikos Karamanos; Elias Panagiotopoulos
Evaluation of modal damping factor as a diagnostic tool for osteoporosis and its relation with serum osteocalcin and collagen I N-telopeptide for monitoring the efficacy of alendronate in ovariectomized rats.
Journal of pharmaceutical and biomedical analysis 2006;41(3):891-7.
2006: Fotini N Lamari; Achilleas D Theocharis; Athanasia P Asimakopoulou; Christina J Malavaki; Nikos Karamanos
Metabolism and biochemical/physiological roles of chondroitin sulfates: analysis of endogenous and supplemental chondroitin sulfates in blood circulation.
Biomedical chromatography : BMC 2006;20(6-7):539-50.
2006: George N Tzanakakis; Alexandra Syrokou; Ioannis Kanakis; Nikos Karamanos
Determination and distribution of N-acetyl- and N-glycolylneuraminic acids in culture media and cell-associated glycoconjugates from human malignant mesothelioma and adenocarcinoma cells.
Biomedical chromatography : BMC 2006;20(5):434-9.
2006: Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells.
Mini reviews in medicinal chemistry 2006;6(3):331-7.
2006: Constantinos D Georgakopoulos; Artemis M Exarchou; Sotirios P Gartaganis; Fevronia Kolonitsiou; Evangelos D Anastassiou; George Dimitracopoulos; A Hjerpe; Achilleas D Theocharis; Nikos Karamanos
Immunization with specific polysaccharide antigen reduces alterations in corneal proteoglycans during experimental slime-producing Staphylococcus epidermidis keratitis.
Current eye research 2006;31(2):137-46.
2006: Kalea Anastasia; Fotini N Lamari; Achilleas D Theocharis; Paul Cordopatis; Dale A Schuschke; Nikos Karamanos; Dorothy Klimis-Zacas
Wild blueberry (Vaccinium angustifolium) consumption affects the composition and structure of glycosaminoglycans in Sprague-Dawley rat aorta.
The Journal of nutritional biochemistry 2006;17(2):109-16.
2006: Achilleas D Theocharis; Ioannis Tsolakis; George N Tzanakakis; Nikos Karamanos
Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression.
Advances in pharmacology (San Diego, Calif.) 2006;53():281-95.
2006: Fotini N Lamari; Nikos Karamanos
Structure of chondroitin sulfate.
Advances in pharmacology (San Diego, Calif.) 2006;53():33-48.
2006: E Fthenou; Alexandros Zafiropoulos; Aristidis M Tsatsakis; A Stathopoulos; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate A chains enhance platelet derived growth factor-mediated signalling in fibrosarcoma cells.
The international journal of biochemistry & cell biology 2006;38(12):2141-50.
2006: Dragana Nikitovic; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Achilleas D Theocharis; Nikos Karamanos; George N Tzanakakis
Transforming growth factor-beta as a key molecule triggering the expression of versican isoforms v0 and v1, hyaluronan synthase-2 and synthesis of hyaluronan in malignant osteosarcoma cells.
IUBMB life 2006;58(1):47-53.
2005: Aikaterini A Zompra; Vassiliki Magafa; Fotini N Lamari; Anastasia Nikolopoulou; Berthold A Nock; Theodosia Maina; Georgios A A. Spyroulias; Nikos Karamanos; Paul Cordopatis
GnRH analogues containing conformationally restricted amino acids in positions 3 and 6: differential impact on pituitary binding affinity and direct antiproliferative effect on breast cancer cells.
The journal of peptide research : official journal of the American Peptide Society 2005;66 Suppl 1():57-64.
2005: Theodore Tselios; Fotini N Lamari; Ioanna Karathanasopoulou; Maria Katsara; Vasso Apostolopoulos; Geoffrey A Pietersz; John Matsoukas; Nikos Karamanos
Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.
Analytical biochemistry 2005;347(1):121-8.
2005: Evgenia G Karousou; Manuela Viola; Anna Genasetti; Davide Vigetti; Giancarlo De Luca; Nikos Karamanos; Alberto Passi
Application of polyacrylamide gel electrophoresis of fluorophore-labeled saccharides for analysis of hyaluronan and chondroitin sulfate in human and animal tissues and cell cultures.
Biomedical chromatography : BMC 2005;19(10):761-5.
2005: Dragana Nikitovic; Alexandros Zafiropoulos; George N Tzanakakis; Nikos Karamanos; Aristidis M Tsatsakis
Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions.
Anticancer research 2005;25(4):2851-6.
2005: Olga C Kousidou; Theoni N Mitropoulou; Andreas E Roussidis; Dimitris Kletsas; Achilleas D Theocharis; Nikos Karamanos
Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.
International journal of oncology 2005;26(4):1101-9.
2005: Dimitrios Pectasides; Maria Nikolaou; Dimitrios Farmakis; Ioannis Kanakis; Asimina Gaglia; Panteleimon Kountourakis; Nikos Karamanos; Theofanis Economopoulos; Sotirios A Raptis
Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid.
Anticancer research 2005;25(2B):1457-63.
2005: V I Kozanidou; Achilleas D Theocharis; Athanasios N Georgiadis; P V Voulgari; Alexandros A Drosos; Nikos Karamanos
Signal transduction by IL-2 and its receptors as target in treatment of rheumatoid arthritis.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(1):41-50.
2005: Dimitrios Pectasides; Dimitrios Farmakis; Maria Nikolaou; Ioannis Kanakis; Vassiliki Kostopoulou; Ioannis Papaconstantinou; Nikos Karamanos; Theofanis Economopoulos; Sotirios A Raptis
Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer.
Journal of pharmaceutical and biomedical analysis 2005;37(1):171-6.
2005: Anastasia Stavropoulou; Gina E Christopoulou; George Anastassopoulos; Sofia D Panteliou; George P Lyritis; Bessie E Spiliotis; Nikos Karamanos; Elias Panagiotopoulos; Elias Lambiris
Alteration in serum leptin correlates with alterations in serum N-telopeptide of collagen type I and serum osteocalcin during the progression of osteoporosis in ovariectomized rats.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2005;43(12):1359-65.
2005: Ioannis Kanakis; Olga Ch Kousidou; Nikos Karamanos
In vitro and in vivo antiresorptive effects of bisphosphonates in metastatic bone disease.
In vivo (Athens, Greece) 2005;19(1):311-8.
2004: Olga C Kousidou; Andreas E Roussidis; Achilleas D Theocharis; Nikos Karamanos
Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential.
Anticancer research 2004;24(6):4025-30.
2004: Argiris V Noulas; Spyros S Skandalis; Elias Feretis; Dimitrios A Theocharis; Nikos Karamanos
Variations in content and structure of glycosaminoglycans of the vitreous gel from different mammalian species.
Biomedical chromatography : BMC 2004;18(7):457-61.
2004: A Tsilemou; M Assouti; Nickoletta Papageorgakopoulou; Nikos Karamanos; Constantinos P Tsiganos; Demitrios H Vynios
The presence of a novel extracellular hyaluronidase in squid cranial cartilage.
Biochimie 2004;86(8):579-86.
2004: Andreas E Roussidis; Theoni N Mitropoulou; Achilleas D Theocharis; Christos Kiamouris; S Papadopoulos; Dimitris Kletsas; Nikos Karamanos
STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells.
Anticancer research 2004;24(3a):1445-7.
2004: Theoni N Mitropoulou; Achilleas D Theocharis; Dragana Nikitovic; Nikos Karamanos; George N Tzanakakis
IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and -independent pathways.
Biochimie 2004;86(4-5):251-9.
2004: Ioannis Kanakis; Maria Nikolaou; Dimitrios Pectasides; Christos Kiamouris; Nikos Karamanos
Determination and biological relevance of serum cross-linked type I collagen N-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer.
Journal of pharmaceutical and biomedical analysis 2004;34(4):827-32.
2004: Xanthee M Gioldassi; H Papadimitriou; V Mikraki; Nikos Karamanos
Clara cell secretory protein: determination of serum levels by an enzyme immunoassay and its importance as an indicator of bronchial asthma in children.
Journal of pharmaceutical and biomedical analysis 2004;34(4):823-6.
2004: Fotini N Lamari; Evangelos D Anastassiou; Fevronia Kolonitsiou; George Dimitracopoulos; Nikos Karamanos
Potential use of solid phase immunoassays in the diagnosis of coagulase-negative staphylococcal infections.
Journal of pharmaceutical and biomedical analysis 2004;34(4):803-10.
2003: Achilleas D Theocharis; Ioannis Tsolakis; Anders Hjerpe; Nikos Karamanos
Versican undergoes specific alterations in the fine molecular structure and organization in human aneurysmal abdominal aortas.
Biomedical chromatography : BMC 2003;17(6):411-6.
2003: Maria Militsopoulou; Fotini N Lamari; Nikos Karamanos
Capillary electrophoresis: a tool for studying interactions of glycans/proteoglycans with growth factors.
Journal of pharmaceutical and biomedical analysis 2003;32(4-5):823-8.
2003: Fotini N Lamari; Reinhard Kuhn; Nikos Karamanos
Derivatization of carbohydrates for chromatographic, electrophoretic and mass spectrometric structure analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;793(1):15-36.
2003: Evdokia Makatsori; Fotini N Lamari; Achilleas D Theocharis; S Th Anagnostides; Anders Hjerpe; Theodore Tsegenidis; Nikos Karamanos
Large matrix proteoglycans, versican and perlecan, are expressed and secreted by human leukemic monocytes.
Anticancer research 2003;23(4):3303-9.
2003: Theoni N Mitropoulou; George N Tzanakakis; Dimitris Kletsas; Haralabos P Kalofonos; Nikos Karamanos
Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells.
International journal of cancer. Journal international du cancer 2003;104(2):155-60.
2003: Dragana Nikitovic; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
The effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density.
Anticancer research 2003;23(1A):459-64.
2003: V Dimitrellos; Fotini N Lamari; Maria Militsopoulou; Ioannis Kanakis; Nikos Karamanos
Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor.
Biomedical chromatography : BMC 2003;17(1):42-7.
2003: Maria Militsopoulou; Céline Lecomte; Christopher Bayle; François Couderc; Nikos Karamanos
Laser-induced fluorescence as a powerful detection tool for capillary electrophoretic analysis of heparin/heparan sulfate disaccharides.
Biomedical chromatography : BMC 2003;17(1):39-41.
2002: Demitrios H Vynios; Nikos Karamanos; Constantinos P Tsiganos
Advances in analysis of glycosaminoglycans: its application for the assessment of physiological and pathological states of connective tissues.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;781(1-2):21-38.
2002: Fotini N Lamari; Nikos Karamanos
Separation methods for sialic acids and critical evaluation of their biologic relevance.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;781(1-2):3-19.
2002: Achilleas D Theocharis; Nikos Karamanos
Decreased biglycan expression and differential decorin localization in human abdominal aortic aneurysms.
Atherosclerosis 2002;165(2):221-30.
2002: Alexandra Syrokou; Katalin Dobra; George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Synthesis and expression of mRNA encoding for different versican splice variants is related to the aggregation of human epithelial mesothelioma cells.
Anticancer research 2002;22(6C):4157-62.
2002: Andreas E Roussidis; Nikos Karamanos
Inhibition of receptor tyrosine kinase-based signal transduction as specific target for cancer treatment.
In vivo (Athens, Greece) 2002;16(6):459-69.
2002: Theoni N Mitropoulou; George N Tzanakakis; Dragana Nikitovic; Aristidis M Tsatsakis; Nikos Karamanos
In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptor-positive and -negative human breast cancer epithelial cells.
Anticancer research 2002;22(5):2841-6.
2002: Achilleas D Theocharis; Dimitrios A Theocharis; Giancarlo De Luca; Anders Hjerpe; Nikos Karamanos
Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aorta.
Biochimie 2002;84(7):667-74.
2002: Constantinos D Georgakopoulos; Artemis M Exarchou; John X Koliopoulos; Sotirios P Gartaganis; Evangelos D Anastassiou; Fevronia Kolonitsiou; Fotini N Lamari; Nikos Karamanos; George Dimitracopoulos
Levels of specific antibodies towards the major antigenic determinant of slime-producing Staphylococcus epidermidis determined by an enzyme immunoassay and their protective effect in experimental keratitis.
Journal of pharmaceutical and biomedical analysis 2002;29(1-2):255-62.
2002: Efstathios S Gonos; D Agrafiotis; A S Dontas; S Efthimiopoulos; Dimitrios Galaris; Nikos Karamanos; Dimitris Kletsas; Evangelos Kolettas; George Panayotou; Harris Pratsinis; Kalliope E Sekeri-Pataryas; D Simoes; Thomae G Sourlingas; Dimitri Stathakos; A J Stratigos; Nektarios Tavernarakis; Ioannis P Trougakos; Constantinos P Tsiganos; Demitrios H Vynios
Ageing research in Greece.
Experimental gerontology 2002;37(6):735-47.
2002: P Katsougraki; J Heliopoulos; Fotini N Lamari; Maria Militsopoulou; S Th Anagnostides; H Piperidou; Dimitri S Monos; Nikos Karamanos
Identification of kappa and lambda chains of the major immunoglobulin G subclasses by capillary zone electrophoresis.
Biomedical chromatography : BMC 2002;16(3):234-6.
2002: Argiris V Noulas; Achilleas D Theocharis; Elias Feretis; Nickoletta Papageorgakopoulou; Nikos Karamanos; Dimitrios A Theocharis
Pig vitreous gel: macromolecular composition with particular reference to hyaluronan-binding proteoglycans.
Biochimie 2002;84(4):295-302.
2002: Maria Militsopoulou; Fotini N Lamari; Anders Hjerpe; Nikos Karamanos
Determination of twelve heparin- and heparan sulfate-derived disaccharides as 2-aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser-induced fluorescence detection.
Electrophoresis 2002;23(7-8):1104-9.
2002: K Strousopoulou; Maria Militsopoulou; Konstantinos D Stagiannis; Fotini N Lamari; Nikos Karamanos
A capillary zone electrophoresis method for determining N-acetylneuraminic acid in glycoproteins and blood sera.
Biomedical chromatography : BMC 2002;16(2):146-50.
2002: Fotini N Lamari; Xanthee M Gioldassi; Theoni N Mitropoulou; Nikos Karamanos
Structure analysis of lipoglycans and lipoglycan-derived carbohydrates by capillary electrophoresis and mass spectrometry.
Biomedical chromatography : BMC 2002;16(2):116-26.
2002: Fotini N Lamari; Maria Militsopoulou; Theoni N Mitropoulou; Anders Hjerpe; Nikos Karamanos
Analysis of glycosaminoglycan-derived disaccharides in biologic samples by capillary electrophoresis and protocol for sequencing glycosaminoglycans.
Biomedical chromatography : BMC 2002;16(2):95-102.
2002: Achilleas D Theocharis; Nikos Karamanos; Nickoletta Papageorgakopoulou; Constantinos P Tsiganos; Dimitrios A Theocharis
Isolation and characterization of matrix proteoglycans from human nasal cartilage. Compositional and structural comparison between normal and scoliotic tissues.
Biochimica et biophysica acta 2002;1569(1-3):117-26.
2001: Sotirios P Gartaganis; Constantinos D Georgakopoulos; Artemis M Exarchou; Ephigenia K Mela; Fotini N Lamari; Nikos Karamanos
Increased aqueous humor basic fibroblast growth factor and hyaluronan levels in relation to the exfoliation syndrome and exfoliative glaucoma.
Acta ophthalmologica Scandinavica 2001;79(6):572-5.
2001: Evdokia Makatsori; Theodore Tsegenidis; Nikos Karamanos
Effects of mitogens on synthesis and distribution of heparan and chondroitin sulphates by human leukemic B, T cells and monocytes studied by high-performance liquid chromatography and radiochemical detection.
Biomedical chromatography : BMC 2001;15(8):534-8.
2001: Evdokia Makatsori; Nikos Karamanos; N Papadogiannakis; Anders Hjerpe; Evangelos D Anastassiou; Theodore Tsegenidis
Synthesis and distribution of glycosaminoglycans in human leukemic B- and T-cells and monocytes studied using specific enzymic treatments and high-performance liquid chromatography.
Biomedical chromatography : BMC 2001;15(6):413-7.
2001: Fotini N Lamari; Maria Militsopoulou; Xanthee M Gioldassi; Nikos Karamanos
Capillary electrophoresis: a superior miniaturized tool for analysis of the mono-, di-, and oligosaccharide constituents of glycan moieties in proteoglycans.
Fresenius' journal of analytical chemistry 2001;371(2):157-67.
2001: Orthodoxia Mastrogianni; Fotini N Lamari; Alexandra Syrokou; Maria Militsopoulou; Anders Hjerpe; Nikos Karamanos
Microemulsion electrokinetic capillary chromatography of sulfated disaccharides derived from glycosaminoglycans.
Electrophoresis 2001;22(13):2743-5.
2001: Theoni N Mitropoulou; Fotini N Lamari; Alexandra Syrokou; Anders Hjerpe; Nikos Karamanos
Identification of oligomeric domains within dermatan sulfate chains using differential enzymic treatments, derivatization with 2-aminoacridone and capillary electrophoresis.
Electrophoresis 2001;22(12):2458-63.
2001: Theoni N Mitropoulou; Achilleas D Theocharis; Konstantinos D Stagiannis; Nikos Karamanos
Identification, quantification and fine structural characterization of glycosaminoglycans from uterine leiomyoma and normal myometrium.
Biochimie 2001;83(6):529-36.
2001: K N Korizis; Artemis M Exarchou; E Michalopoulos; Constantinos D Georgakopoulos; Fevronia Kolonitsiou; Stefanos Mantagos; Sotirios P Gartaganis; Nikos Karamanos
Determination of malondialdehyde by capillary electrophoresis, application to human plasma and relation of its levels with prematurity.
Biomedical chromatography : BMC 2001;15(4):287-91.
2001: G Balayiannis; Dionissios Papaioannou; Nikos Karamanos
Application of capillary electrophoresis in the analysis of novel synthetic dideoxynucleoside analogues with potential anti-HIV activity.
Biomedical chromatography : BMC 2001;15(4):271-3.
2001: Achilleas D Theocharis; Ioannis Tsolakis; Anders Hjerpe; Nikos Karamanos
Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0).
Atherosclerosis 2001;154(2):367-76.
2001: Nikos Karamanos; Anders Hjerpe
Intact and oligomeric glycosaminoglycans analyzed with capillary electrophoresis.
Methods in molecular biology (Clifton, N.J.) 2001;171():193-8.
2001: Nikos Karamanos; Anders Hjerpe
Disaccharide composition in glycosaminoglycans/proteoglycans analyzed by capillary zone electrophoresis.
Methods in molecular biology (Clifton, N.J.) 2001;171():181-92.
2001: Fevronia Kolonitsiou; Alexandra Syrokou; Nikos Karamanos; Evangelos D Anastassiou; George Dimitracopoulos
Immunoreactivity of 80-kDa peptidoglycan and teichoic acid-like substance of slime producing S. epidermidis and specificity of their antibodies studied by an enzyme immunoassay.
Journal of pharmaceutical and biomedical analysis 2001;24(3):429-36.
2000: Fotini N Lamari; Evangelos D Anastassiou; George Dimitracopoulos; Nikos Karamanos
Immunochemical-based assays in the bioanalysis of immunoglobulins.
Journal of pharmaceutical and biomedical analysis 2000;23(6):939-46.
2000: Fotini N Lamari; Evangelos D Anastassiou; E Stamokosta; S Photopoulos; M Xanthou; George Dimitracopoulos; Nikos Karamanos
Determination of slime-producing S. epidermidis specific antibodies in human immunoglobulin preparations and blood sera by an enzyme immunoassay: correlation of antibody titers with opsonic activity and application to preterm neonates.
Journal of pharmaceutical and biomedical analysis 2000;23(2-3):363-74.
2000: D N Tzovolou; Fotini N Lamari; Ephigenia K Mela; Sotirios P Gartaganis; Nikos Karamanos
Capillary electrophoretic analysis of brimonidine in aqueous humor of the eye and blood sera and relation of its levels with intraocular pressure.
Biomedical chromatography : BMC 2000;14(5):301-5.
2000: Katalin Dobra; Michael Andäng; Alexandra Syrokou; Nikos Karamanos; Anders Hjerpe
Differentiation of mesothelioma cells is influenced by the expression of proteoglycans.
Experimental cell research 2000;258(1):12-22.
2000: Fotini N Lamari; Nikos Karamanos; E Papadopoulou-Alataki; F Kanakoudi-Tsakalidou; George Dimitracopoulos; Evangelos D Anastassiou
Monitoring of two intravenous immunoglobulin. Preparations for immunoglobulin G subclasses and specific antibodies to bacterial surface antigens and relation with their levels in treated immunodeficient patients.
Journal of pharmaceutical and biomedical analysis 2000;22(6):1029-36.
1999: Nikos Karamanos; Anders Hjerpe
Strategies for analysis and structure characterization of glycans/proteoglycans by capillary electrophoresis. Their diagnostic and biopharmaceutical importance.
Biomedical chromatography : BMC 1999;13(8):507-12.
1999: Nikos Karamanos; Fotini N Lamari
State-of-the-art of capillary electrophoresis with application to the area of glycoconjugates.
Biomedical chromatography : BMC 1999;13(8):501-6.
1999: Achilleas D Theocharis; Nikos Karamanos; Theodore Tsegenidis
Isolation and analysis of a novel acidic polysaccharide from the case of squid pen.
International journal of biological macromolecules 1999;26(1):83-8.
1999: S Diamantopoulou; Konstantinos D Stagiannis; K Vasilopoulos; P Barlas; Theodore Tsegenidis; Nikos Karamanos
Importance of high-performance liquid chromatographic analysis of serum N-acylneuraminic acids in evaluating surgical treatment in patients with early endometrial cancer.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(2):375-81.
1999: Fotini N Lamari; Evangelos D Anastassiou; Theodore Tsegenidis; George Dimitracopoulos; Nikos Karamanos
An enzyme immunoassay to determine the levels of specific antibodies toward bacterial surface antigens in human immunoglobulin preparations and blood serum.
Journal of pharmaceutical and biomedical analysis 1999;20(6):913-20.
1999: Sotirios P Gartaganis; Ephigenia K Mela; John M Katsimpris; J K Petropoulos; Nikos Karamanos; John X Koliopoulos
Use of topical brimonidine to prevent intraocular pressure elevations following Nd:YAG-laser posterior capsulotomy.
Ophthalmic surgery and lasers 1999;30(8):647-52.
1999: Achilleas D Theocharis; Ioannis Tsolakis; Theodore Tsegenidis; Nikos Karamanos
Human abdominal aortic aneurysm is closely associated with compositional and specific structural modifications at the glycosaminoglycan level.
Atherosclerosis 1999;145(2):359-68.
1999: Alexandra Syrokou; George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Proteoglycans in human malignant mesothelioma. Stimulation of their synthesis induced by epidermal, insulin and platelet-derived growth factors involves receptors with tyrosine kinase activity.
Biochimie 1999;81(7):733-44.
1999: Fotini N Lamari; Achilleas D Theocharis; Anders Hjerpe; Nikos Karamanos
Ultrasensitive capillary electrophoresis of sulfated disaccharides in chondroitin/dermatan sulfates by laser-induced fluorescence after derivatization with 2-aminoacridone.
Journal of chromatography. B, Biomedical sciences and applications 1999;730(1):129-33.
1999: Alexandra Syrokou; George N Tzanakakis; Theodore Tsegenidis; Anders Hjerpe; Nikos Karamanos
Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure-function relationship.
Cell proliferation 1999;32(2-3):85-99.
1999: C C Chatziioannidis; Nikos Karamanos; S Th Anagnostides; Theodore Tsegenidis
Purification and characterisation of a minor low-sulphated dermatan sulphate-proteoglycan from ray skin.
Biochimie 1999;81(3):187-96.
1999: Nikos Karamanos; Fotini N Lamari; John M Katsimpris; Sotirios P Gartaganis
Development of an HPLC method for determining the alpha 2-adrenergic receptor agonist brimonidine in blood serum and aqueous humor of the eye.
Biomedical chromatography : BMC 1999;13(1):86-8.
1999: Evdokia Makatsori; Alexios J Aletras; Nikos Karamanos; Theodore Tsegenidis
Analysis of N-acetyl and N-glycolylneuraminic acid in rat serum and tissues with Walker 256 carcinoma by high-performance liquid chromatography.
Biomedical chromatography : BMC 1999;13(1):57-60.
1998: Nikos Karamanos; Anders Hjerpe
A survey of methodological challenges for glycosaminoglycan/proteoglycan analysis and structural characterization by capillary electrophoresis.
Electrophoresis 1998;19(15):2561-71.
1998: Evdokia Makatsori; K Fermani; Alexios J Aletras; Nikos Karamanos; Theodore Tsegenidis
Screening of N-acylneuraminic acids in serum and tissue specimens of mouse C57BI with Lewis' lung cancer by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1998;712(1-2):23-9.
1998: Nikos Karamanos
Glycosylation of proteins: specificity, biological role, and analysis of glycan moieties.
Journal of protein chemistry 1998;17(6):513-4.
1998: Fotini N Lamari; John M Katsimpris; Sotirios P Gartaganis; Nikos Karamanos
Profiling of the eye aqueous humor in exfoliation syndrome by high-performance liquid chromatographic analysis of hyaluronan and galactosaminoglycans.
Journal of chromatography. B, Biomedical sciences and applications 1998;709(2):173-8.
1997: Nikos Karamanos; Anders Hjerpe
High-performance capillary electrophoretic analysis of hyaluronan in effusions from human malignant mesothelioma.
Journal of chromatography. B, Biomedical sciences and applications 1997;697(1-2):277-81.
1997: Nikos Karamanos; Alexandra Syrokou; H S Panagiotopoulou; Evangelos D Anastassiou; George Dimitracopoulos
The major 20-kDa polysaccharide of Staphylococcus epidermidis extracellular slime and its antibodies as powerful agents for detecting antibodies in blood serum and differentiating among slime-positive and -negative S. epidermidis and other staphylococci species.
Archives of biochemistry and biophysics 1997;342(2):389-95.
1997: George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Proteoglycan synthesis induced by transforming and basic fibroblast growth factors in human malignant mesothelioma is mediated through specific receptors and the tyrosine kinase intracellular pathway.
Biochimie 1997;79(6):323-32.
1997: Nikos Karamanos; P Vanky; George N Tzanakakis; Theodore Tsegenidis; Anders Hjerpe
Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate.
Journal of chromatography. A 1997;765(2):169-79.
1996: George N Tzanakakis; Nikos Karamanos; Alexandra Syrokou; Anders Hjerpe
Effect of insulin and epidermal growth factors on the synthesis of glycosaminoglycans/proteoglycans in cultured human malignant mesothelioma cells of different phenotypic morphology.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1996;104(10):718-28.
1996: Nikos Karamanos; P Vanky; George N Tzanakakis; Anders Hjerpe
High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharides.
Electrophoresis 1996;17(2):391-5.
1996: Nikos Karamanos; A Manouras; S Anagnostides; Evdokia Makatsori; Theodore Tsegenidis; C A Antonopoulos
Isolation, biochemical and immunological characterisation of two sea urchin glycoproteins bearing sulphated poly(sialic acid) polysaccharides rich in N-glycolyl neuraminic acid.
Biochimie 1996;78(3):171-82.
1995: George N Tzanakakis; Nikos Karamanos; Anders Hjerpe
Effects on glycosaminoglycan synthesis in cultured human mesothelioma cells of transforming, epidermal, and fibroblast growth factors and their combinations with platelet-derived growth factor.
Experimental cell research 1995;220(1):130-7.
1995: Nikos Karamanos; S Axelsson; P Vanky; George N Tzanakakis; Anders Hjerpe
Determination of hyaluronan and galactosaminoglycan disaccharides by high-performance capillary electrophoresis at the attomole level. Applications to analyses of tissue and cell culture proteoglycans.
Journal of chromatography. A 1995;696(2):295-305.
1995: Nikos Karamanos; P Vanky; Alexandra Syrokou; Anders Hjerpe
Identity of dermatan and chondroitin sequences in dermatan sulfate chains determined by using fragmentation with chondroitinases and ion-pair high-performance liquid chromatography.
Analytical biochemistry 1995;225(2):220-30.
1995: Nikos Karamanos; Anders Hjerpe; Alexios J Aletras; Theodore Tsegenidis; Evangelos D Anastassiou; C A Antonopoulos
Antibodies to three chondroitin sulfate-containing proteoglycans in squid skin recognize hexa- or longer chondroitin oligosaccharides as major antigenic determinants.
Archives of biochemistry and biophysics 1995;316(1):100-9.
1995: George N Tzanakakis; Nikos Karamanos; Julius Klominek; Anders Hjerpe
Glycosaminoglycans from two human malignant mesothelioma cell lines: determination, distribution, and effect of platelet-derived growth factor on their synthesis.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1995;73(1-2):59-66.
1995: Nikos Karamanos; H S Panagiotopoulou; Alexandra Syrokou; C Frangides; Anders Hjerpe; George Dimitracopoulos; Evangelos D Anastassiou
Identity of macromolecules present in the extracellular slime layer of Staphylococcus epidermidis.
Biochimie 1995;77(3):217-24.
1994: Nikos Karamanos; Alexandra Syrokou; P Vanky; M Nurminen; Anders Hjerpe
Determination of 24 variously sulfated galactosaminoglycan- and hyaluronan-derived disaccharides by high-performance liquid chromatography.
Analytical biochemistry 1994;221(1):189-99.
1994: A Arvaniti; Nikos Karamanos; George Dimitracopoulos; Evangelos D Anastassiou
Isolation and characterization of a novel 20-kDa sulfated polysaccharide from the extracellular slime layer of Staphylococcus epidermidis.
Archives of biochemistry and biophysics 1994;308(2):432-8.
1994: Nikos Karamanos; Alexios J Aletras; C A Antonopoulos; Anders Hjerpe
Determination of the HNK-1 epitope (3-sulphated glucuronic acid) in intact chondroitin sulphates by ELISA. Application to squid skin proteoglycans and their oversulphated carbohydrate structures.
Biochimie 1994;76(1):79-82.
1993: M Christofidou; Nikos Karamanos; Anastassios C Mintzas; George Dimitracopoulos; Evangelos D Anastassiou
Occurrence of a 29 kDa polysaccharide in the slime layer of both smooth and rough strains of Pseudomonas aeruginosa.
The International journal of biochemistry 1993;25(3):313-8.
1992: Nikos Karamanos
Two squid skin proteoglycans each containing chondroitin sulfates with different sulfation patterns.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1992;70(8):629-35.
1992: Nikos Karamanos; Alexios J Aletras; Theodore Tsegenidis; Constantinos P Tsiganos; C A Antonopoulos
Isolation, characterization and properties of the oversulphated chondroitin sulphate proteoglycan from squid skin with peculiar glycosaminoglycan sulphation pattern.
European journal of biochemistry / FEBS 1992;204(2):553-60.
1991: Alexios J Aletras; Nikos Karamanos; Anders Hjerpe
Presence of the HNK-1 epitope (3-sulfoglucuronic acid) on oligosaccharides from squid skin chondroitin proteoglycans and degradation of proteoglycans by proteolytic enzymes.
Biochemistry international 1991;25(2):331-8.
1991: Nikos Karamanos; A Manouras; Theodore Tsegenidis; C A Antonopoulos
Isolation and chemical study of the glycosaminoglycans from squid cornea.
The International journal of biochemistry 1991;23(1):67-72.
1988: Nikos Karamanos; Anders Hjerpe; Theodore Tsegenidis; B Engfeldt; C A Antonopoulos
Determination of iduronic acid and glucuronic acid in glycosaminoglycans after stoichiometric reduction and depolymerization using high-performance liquid chromatography and ultraviolet detection.
Analytical biochemistry 1988;172(2):410-9.
1988: Nikos Karamanos; Alexios J Aletras; C A Antonopoulos; Theodore Tsegenidis; Constantinos P Tsiganos; Demitrios H Vynios
Extraction and fractionation of proteoglycans from squid skin.
Biochimica et biophysica acta 1988;966(1):36-43.