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Nagako Akeno

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Nagako Akeno; Eric P Smith; Mihaela Stefan; Amanda K Huber; Weijia Zhang; Mehdi Keddache; Yaron Tomer
IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms.
Xu Chen; Norisato Mitsutake; Krista LaPerle; Nagako Akeno; Pat Zanzonico; Valerie A Longo; Shin Mitsutake; Edna T Kimura; Hartmut Geiger; Eugenio Santos; Hans-Guido Wendel; Aime Franco; Jeffrey A Knauf; James A Fagin
Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.
Nagako Akeno; Jason T Blackard; Yaron Tomer
HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity.

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All Publications

2011: Nagako Akeno; Eric P Smith; Mihaela Stefan; Amanda K Huber; Weijia Zhang; Mehdi Keddache; Yaron Tomer
IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4693-706.
2009: Xu Chen; Norisato Mitsutake; Krista LaPerle; Nagako Akeno; Pat Zanzonico; Valerie A Longo; Shin Mitsutake; Edna T Kimura; Hartmut Geiger; Eugenio Santos; Hans-Guido Wendel; Aime Franco; Jeffrey A Knauf; James A Fagin
Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7979-84.
2008: Nagako Akeno; Jason T Blackard; Yaron Tomer
HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity.
Journal of autoimmunity 2008;31(4):339-44.
2008: Mickey Croyle; Nagako Akeno; Jeffrey A Knauf; Doriano Fabbro; Xu Chen; Jacqueline E Baumgartner; Heidi A Lane; James A Fagin
RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR.
Cancer research 2008;68(11):4183-91.
2007: Yaron Tomer; Jason T Blackard; Nagako Akeno
Interferon alpha treatment and thyroid dysfunction.
Endocrinology and metabolism clinics of North America 2007;36(4):1051-66; x-xi.
2007: Eric M Jacobson; A K Huber; Nagako Akeno; M Sivak; C W Li; Erlinda Concepcion; K Ho; Yaron Tomer
A CD40 Kozak sequence polymorphism and susceptibility to antibody-mediated autoimmune conditions: the role of CD40 tissue-specific expression.
Genes and immunity 2007;8(3):205-14.
2006: Norisato Mitsutake; Makoto Miyagishi; Shin Mitsutake; Nagako Akeno; Cleo Mesa; Jeffrey A Knauf; Lei Zhang; Kazunari Taira; James A Fagin
BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis.
Endocrinology 2006;147(2):1014-9.
2005: Jared C Robins; Nagako Akeno; Aditi Mukherjee; Ravi R Dalal; Bruce Aronow; Peter Koopman; Thomas Landes Clemens
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.
Bone 2005;37(3):313-22.
2005: Meilan M Rutter; Edith Markoff; Lisa Clayton; Nagako Akeno; Guisheng Zhao; Thomas Landes Clemens; Steven D Chernausek
Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5.
Bone 2005;36(2):224-31.
2002: Mei Zhang; Shouhong Xuan; Mary L Bouxsein; Dietrich von Stechow; Nagako Akeno; Marie-Claude Faugere; Hartmut H Malluche; Guisheng Zhao; Clifford J Rosen; Argiris Efstratiadis; Thomas Landes Clemens
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization.
The Journal of biological chemistry 2002;277(46):44005-12.
2002: Nagako Akeno; Jared C Robins; Mei Zhang; Maria F Czyzyk-Krzeska; Thomas Landes Clemens
Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha.
Endocrinology 2002;143(2):420-5.
2001: Ted S Gross; Nagako Akeno; Thomas Landes Clemens; Svetlana V Komarova; Sundar Srinivasan; D A Weimer; Sergey Mayorov
Selected Contribution: Osteocytes upregulate HIF-1alpha in response to acute disuse and oxygen deprivation.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(6):2514-9.
2001: Nagako Akeno; Maria F Czyzyk-Krzeska; Ted S Gross; Thomas Landes Clemens
Hypoxia induces vascular endothelial growth factor gene transcription in human osteoblast-like cells through the hypoxia-inducible factor-2alpha.
Endocrinology 2001;142(2):959-62.