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Martin Helmer
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13
Stipp, Christopher
12
Chan, Bosco
11
Strominger, Jack
10
Berditchevski, F
8
Kolesnikova, Tatiana
6
Lobb, Roy
6
Kazarov, Alexander
5
Kovalenko, Oleg
5
Bergelson, Jeffrey
5
Yauch, RL
5
Zhang, Xin
5
Yang, Xiuwei
4
Jacobson, Jennie
4
Mann, Dean
4
Chen, Lan Bo
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All Publications
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2008: Sharma Chandan; Yang Xiuwei H; Hemler Martin E
DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151.
Molecular biology of the cell 2008;19(8):3415-25.
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2008: Yang Xiuwei H; Richardson Andrea L; Torres-Arzayus Maria I; Zhou Pengcheng; Sharma Chandan; Kazarov Alexander R; Andzelm Milena M; Strominger Jack L; Brown Myles; Hemler Martin E
CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization.
Cancer research 2008;68(9):3204-13.
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2007: Kovalenko Oleg V; Yang Xiuwei H; Hemler Martin E
A novel cysteine cross-linking method reveals a direct association between claudin-1 and tetraspanin CD9.
Molecular & cellular proteomics : MCP 2007;6(11):1855-67.
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2007: Takeda Yoshito; Kazarov Alexander R; Butterfield Catherine E; Hopkins Benjamin D; Benjamin Laura E; Kaipainen Arja; Hemler Martin E
Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro.
Blood 2007;109(4):1524-32.
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2006: Wunschmann Sabina; Muller Hubert M; Stipp Christopher S; Hemler Martin E; Stapleton Jack T
In vitro interaction between hepatitis C virus (HCV) envelope glycoprotein E2 and serum lipoproteins (LPs) results in enhanced cellular binding of both HCV E2 and LPs.
The Journal of infectious diseases 2006;194(8):1058-67.
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2006: Sala-Valdés Mónica; Ursa Angeles; Charrin Stéphanie; Rubinstein Eric; Hemler Martin E; Sánchez-Madrid Francisco; Yáñez-Mó María
EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins.
The Journal of biological chemistry 2006;281(28):19665-75.
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2006: Yang Xiuwei H; Kovalenko Oleg V; Kolesnikova Tatiana V; Andzelm Milena M; Rubinstein Eric; Strominger Jack L; Hemler Martin E
Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization.
The Journal of biological chemistry 2006;281(18):12976-85.
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2005: Hemler Martin E
Tetraspanin functions and associated microdomains.
Nature reviews. Molecular cell biology 2005;6(10):801-11.
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2005: Xu Daosong; Hemler Martin E
Metabolic activation-related CD147-CD98 complex.
Molecular & cellular proteomics : MCP 2005;4(8):1061-71.
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2005: Kovalenko Oleg V; Metcalf Douglas G; DeGrado William F; Hemler Martin E
Structural organization and interactions of transmembrane domains in tetraspanin proteins.
BMC structural biology 2005;5():11.
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2004: Yang Xiuwei; Kovalenko Oleg V; Tang Wei; Claas Christoph; Stipp Christopher S; Hemler Martin E
Palmitoylation supports assembly and function of integrin-tetraspanin complexes.
The Journal of cell biology 2004;167(6):1231-40.
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2004: Tang Wei; Chang Sharon B; Hemler Martin E
Links between CD147 function, glycosylation, and caveolin-1.
Molecular biology of the cell 2004;15(9):4043-50.
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2004: Little Kevin D; Hemler Martin E; Stipp Christopher S
Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association.
Molecular biology of the cell 2004;15(5):2375-87.
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2004: Kolesnikova Tatiana V; Stipp Christopher S; Rao Ravi M; Lane William S; Luscinskas Francis W; Hemler Martin E
EWI-2 modulates lymphocyte integrin alpha4beta1 functions.
Blood 2004;103(8):3013-9.
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2004: Tang Wei; Hemler Martin E
Caveolin-1 regulates matrix metalloproteinases-1 induction and CD147/EMMPRIN cell surface clustering.
The Journal of biological chemistry 2004;279(12):11112-8.
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2004: Kovalenko Oleg V; Yang Xiuwei; Kolesnikova Tatiana V; Hemler Martin E
Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking.
The Biochemical journal 2004;377(Pt 2):407-17.
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2003: Stipp Christopher S; Kolesnikova Tatiana V; Hemler Martin E
EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5.
The Journal of cell biology 2003;163(5):1167-77.
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2003: Lammerding Jan; Kazarov Alexander R; Huang Hayden; Lee Richard T; Hemler Martin E
Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7616-21.
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2003: Stipp Christopher S; Kolesnikova Tatiana V; Hemler Martin E
Functional domains in tetraspanin proteins.
Trends in biochemical sciences 2003;28(2):106-12.
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2003: Hemler Martin E
Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain.
Annual review of cell and developmental biology 2003;19():397-422.
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2002: Kazarov Alexander R; Yang Xiuwei; Stipp Christopher S; Sehgal Bantoo; Hemler Martin E
An extracellular site on tetraspanin CD151 determines alpha 3 and alpha 6 integrin-dependent cellular morphology.
The Journal of cell biology 2002;158(7):1299-309.
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2002: Yang Xiuwei; Claas Christoph; Kraeft Stine-Kathrein; Chen Lan Bo; Wang Zemin; Kreidberg Jordan A; Hemler Martin E
Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology.
Molecular biology of the cell 2002;13(3):767-81.
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2002: Zhang Xin A; Kazarov Alexander R; Yang Xiuwei; Bontrager Alexa L; Stipp Christopher S; Hemler Martin E
Function of the tetraspanin CD151-alpha6beta1 integrin complex during cellular morphogenesis.
Molecular biology of the cell 2002;13(1):1-11.
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2001: Hemler M E
Specific tetraspanin functions.
The Journal of cell biology 2001;155(7):1103-7.
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2001: Hemler M E
Retooling of the beta 4 integrin in tumor cells--ligands lost and kinase gained.
Developmental cell 2001;1(6):728-30.
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2001: Stipp C S; Kolesnikova T V; Hemler M E
EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily.
The Journal of biological chemistry 2001;276(44):40545-54.
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2001: Zhang X A; Bontrager A L; Hemler M E
Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins.
The Journal of biological chemistry 2001;276(27):25005-13.
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2001: Sun J; Hemler M E
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Cancer research 2001;61(5):2276-81.
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2001: Claas C; Stipp C S; Hemler M E
Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts.
The Journal of biological chemistry 2001;276(11):7974-84.
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2001: Zhang X A; Bontrager A L; Stipp C S; Kraeft S K; Bazzoni G; Chen L B; Hemler M E
Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement.
Molecular biology of the cell 2001;12(2):351-65.
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2001: Stipp C S; Orlicky D; Hemler M E
FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein.
The Journal of biological chemistry 2001;276(7):4853-62.
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2001: Kolesnikova T V; Mannion B A; Berditchevski F; Hemler M E
Beta1 integrins show specific association with CD98 protein in low density membranes.
BMC biochemistry 2001;2():10.
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2000: Yauch R L; Hemler M E
Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase.
The Biochemical journal 2000;351 Pt 3():629-37.
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2000: Stipp C S; Hemler M E
Transmembrane-4-superfamily proteins CD151 and CD81 associate with alpha 3 beta 1 integrin, and selectively contribute to alpha 3 beta 1-dependent neurite outgrowth.
Journal of cell science 2000;113 ( Pt 11)():1871-82.
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2000: Yauch R L; Kazarov A R; Desai B; Lee R T; Hemler M E
Direct extracellular contact between integrin alpha(3)beta(1) and TM4SF protein CD151.
The Journal of biological chemistry 2000;275(13):9230-8.
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1999: Tachibana I; Hemler M E
Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance.
The Journal of cell biology 1999;146(4):893-904.
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1999: Seipel K; Medley Q G; Kedersha N L; Zhang X A; O'Brien S P; Serra-Pages C; Hemler M E; Streuli M
Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth.
Journal of cell science 1999;112 ( Pt 12)():1825-34.
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1999: Hemler M E
Dystroglycan versatility.
Cell 1999;97(5):543-6.
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1999: Zhang X A; Hemler M E
Interaction of the integrin beta1 cytoplasmic domain with ICAP-1 protein.
The Journal of biological chemistry 1999;274(1):11-9.
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1998: Mannion B A; Kolesnikova T V; Lin S H; Wang S; Thompson N L; Hemler M E
The light chain of CD98 is identified as E16/TA1 protein.
The Journal of biological chemistry 1998;273(50):33127-9.
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1998: Hemler M E
Integrin associated proteins.
Current opinion in cell biology 1998;10(5):578-85.
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1998: Yauch R L; Berditchevski F; Harler M B; Reichner J; Hemler M E
Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration.
Molecular biology of the cell 1998;9(10):2751-65.
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1998: Crommie D; Hemler M E
Beta1 integrin cytoplasmic domain regulates the constitutive conformation detected by MAb 15/7, but not the ligand-induced conformation.
Journal of cellular biochemistry 1998;71(1):63-73.
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1998: Eble J A; Wucherpfennig K W; Gauthier L; Dersch P; Krukonis E; Isberg R R; Hemler M E
Recombinant soluble human alpha 3 beta 1 integrin: purification, processing, regulation, and specific binding to laminin-5 and invasin in a mutually exclusive manner.
Biochemistry 1998;37(31):10945-55.
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1998: Bazzoni G; Ma L; Blue M L; Hemler M E
Divalent cations and ligands induce conformational changes that are highly divergent among beta1 integrins.
The Journal of biological chemistry 1998;273(12):6670-8.
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1998: Bazzoni G; Hemler M E
Are changes in integrin affinity and conformation overemphasized?
Trends in biochemical sciences 1998;23(1):30-4.
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1997: Pujades C; Alon R; Yauch R L; Masumoto A; Burkly L C; Chen C; Springer T A; Lobb R R; Hemler M E
Defining extracellular integrin alpha-chain sites that affect cell adhesion and adhesion strengthening without altering soluble ligand binding.
Molecular biology of the cell 1997;8(12):2647-57.
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1997: Tachibana I; Bodorova J; Berditchevski F; Zutter M M; Hemler M E
NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins.
The Journal of biological chemistry 1997;272(46):29181-9.
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1997: Berditchevski F; Chang S; Bodorova J; Hemler M E
Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6.
The Journal of biological chemistry 1997;272(46):29174-80.
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1997: Yauch R L; Felsenfeld D P; Kraeft S K; Chen L B; Sheetz M P; Hemler M E
Mutational evidence for control of cell adhesion through integrin diffusion/clustering, independent of ligand binding.
The Journal of experimental medicine 1997;186(8):1347-55.
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1997: Weitzman J B; Pujades C; Hemler M E
Integrin alpha chain cytoplasmic tails regulate "antibody-redirected" cell adhesion, independently of ligand binding.
European journal of immunology 1997;27(1):78-84.
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1997: Berditchevski F; Tolias K F; Wong K; Carpenter C L; Hemler M E
A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase.
The Journal of biological chemistry 1997;272(5):2595-8.
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1996: Yuan Q; Strauch K L; Lobb R R; Hemler M E
Intracellular single-chain antibody inhibits integrin VLA-4 maturation and function.
The Biochemical journal 1996;318 ( Pt 2)():591-6.
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1996: Mannion B A; Berditchevski F; Kraeft S K; Chen L B; Hemler M E
Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29).
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):2039-47.
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1996: Weitzman J B; Hemler M E; Brodt P
Reduction of tumorigenicity by alpha 3 integrin in a rhabdomyosarcoma cell line.
Cell adhesion and communication 1996;4(1):41-52.
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1996: Bazzoni G; Carlesso N; Griffin J D; Hemler M E
Bcr/Abl expression stimulates integrin function in hematopoietic cell lines.
The Journal of clinical investigation 1996;98(2):521-8.
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1996: Hemler M E; Mannion B A; Berditchevski F
Association of TM4SF proteins with integrins: relevance to cancer.
Biochimica et biophysica acta 1996;1287(2-3):67-71.
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1996: Berditchevski F; Zutter M M; Hemler M E
Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).
Molecular biology of the cell 1996;7(2):193-207.
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1996: Pujades C; Teixidó J; Bazzoni G; Hemler M E
Integrin alpha 4 cysteines 278 and 717 modulate VLA-4 ligand binding and also contribute to alpha 4/180 formation.
The Biochemical journal 1996;313 ( Pt 3)():899-908.
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1995: Weitzman J B; Chen A; Hemler M E
Investigation of the role of beta 1 integrins in cell-cell adhesion.
Journal of cell science 1995;108 ( Pt 11)():3635-44.
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1995: Bazzoni G; Shih D T; Buck C A; Hemler M E
Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium.
The Journal of biological chemistry 1995;270(43):25570-7.
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1995: Berditchevski F; Bazzoni G; Hemler M E
Specific association of CD63 with the VLA-3 and VLA-6 integrins.
The Journal of biological chemistry 1995;270(30):17784-90.
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1995: Schiffer S G; Hemler M E; Lobb R R; Tizard R; Osborn L
Molecular mapping of functional antibody binding sites of alpha 4 integrin.
The Journal of biological chemistry 1995;270(24):14270-3.
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1995: Kassner P D; Alon R; Springer T A; Hemler M E
Specialized functional properties of the integrin alpha 4 cytoplasmic domain.
Molecular biology of the cell 1995;6(6):661-74.
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1995: Bergelson J M; Hemler M E
Integrin-ligand binding. Do integrins use a 'MIDAS touch' to grasp an Asp?
Current biology : CB 1995;5(6):615-7.
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1995: Alon R; Kassner P D; Carr M W; Finger E B; Hemler M E; Springer T A
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.
The Journal of cell biology 1995;128(6):1243-53.
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1995: Lee R T; Berditchevski F; Cheng G C; Hemler M E
Integrin-mediated collagen matrix reorganization by cultured human vascular smooth muscle cells.
Circulation research 1995;76(2):209-14.
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1995: Hemler M E; Lobb R R
The leukocyte beta 1 integrins.
Current opinion in hematology 1995;2(1):61-7.
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1994: Lobb R R; Hemler M E
The pathophysiologic role of alpha 4 integrins in vivo.
The Journal of clinical investigation 1994;94(5):1722-8.
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1994: Bergelson J M; St John N F; Kawaguchi S; Pasqualini R; Berdichevsky F; Hemler M E; Finberg R W
The I domain is essential for echovirus 1 interaction with VLA-2.
Cell adhesion and communication 1994;2(5):455-64.
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1994: Kawaguchi S; Bergelson J M; Finberg R W; Hemler M E
Integrin alpha 2 cytoplasmic domain deletion effects: loss of adhesive activity parallels ligand-independent recruitment into focal adhesions.
Molecular biology of the cell 1994;5(9):977-88.
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1994: Kassner P D; Kawaguchi S; Hemler M E
Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion.
The Journal of biological chemistry 1994;269(31):19859-67.
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1994: Potts A J; Croall D E; Hemler M E
Proteolytic cleavage of the integrin beta 4 subunit.
Experimental cell research 1994;212(1):2-9.
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1994: Pasqualini R; Hemler M E
Contrasting roles for integrin beta 1 and beta 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration.
The Journal of cell biology 1994;125(2):447-60.
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1993: Masumoto A; Hemler M E
Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin.
The Journal of cell biology 1993;123(1):245-53.
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1993: Mihich E; Hemler M E
Adhesion molecules: cellular recognition mechanisms. The Pezcoller Foundation Symposia, Rovereto, June 24-26, 1992.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1993;4(7):545-7.
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1993: Kawaguchi S; Hemler M E
Role of the alpha subunit cytoplasmic domain in regulation of adhesive activity mediated by the integrin VLA-2.
The Journal of biological chemistry 1993;268(22):16279-85.
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1993: Kassner P D; Hemler M E
Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin.
The Journal of experimental medicine 1993;178(2):649-60.
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1993: Bergelson J M; Chan B M; Finberg R W; Hemler M E
The integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms.
The Journal of clinical investigation 1993;92(1):232-9.
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1993: Hemler M; Mihich E
Fourth annual Pezcoller Symposium--adhesion molecules: cellular recognition mechanisms.
Cancer research 1993;53(9):2192-4.
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1993: Pasqualini R; Bodorova J; Ye S; Hemler M E
A study of the structure, function and distribution of beta 5 integrins using novel anti-beta 5 monoclonal antibodies.
Journal of cell science 1993;105 ( Pt 1)():101-11.
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1993: Weitzman J B; Pasqualini R; Takada Y; Hemler M E
The function and distinctive regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation.
The Journal of biological chemistry 1993;268(12):8651-7.
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1993: Parker C M; Pujades C; Brenner M B; Hemler M E
Alpha 4/180, a novel form of the integrin alpha 4 subunit.
The Journal of biological chemistry 1993;268(10):7028-35.
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1993: Chan B M; Hemler M E
Multiple functional forms of the integrin VLA-2 can be derived from a single alpha 2 cDNA clone: interconversion of forms induced by an anti-beta 1 antibody.
The Journal of cell biology 1993;120(2):537-43.
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1993: Masumoto A; Hemler M E
Multiple activation states of VLA-4. Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1.
The Journal of biological chemistry 1993;268(1):228-34.
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1992: Campanero M R; Arroyo A G; Pulido R; Ursa A; de Matías M S; Sánchez-Mateos P; Kassner P D; Chan B M; Hemler M E; Corbí A L
Functional role of alpha 2/beta 1 and alpha 4/beta 1 integrins in leukocyte intercellular adhesion induced through the common beta 1 subunit.
European journal of immunology 1992;22(12):3111-9.
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1992: Teixidó J; Hemler M E; Greenberger J S; Anklesaria P
Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma.
The Journal of clinical investigation 1992;90(2):358-67.
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1992: Chan B M; Elices M J; Murphy E; Hemler M E
Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY.
The Journal of biological chemistry 1992;267(12):8366-70.
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1992: Bergelson J M; Shepley M P; Chan B M; Hemler M E; Finberg R W
Identification of the integrin VLA-2 as a receptor for echovirus 1.
Science (New York, N.Y.) 1992;255(5052):1718-20.
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1992: Chan B M; Kassner P D; Schiro J A; Byers H R; Kupper T S; Hemler M E
Distinct cellular functions mediated by different VLA integrin alpha subunit cytoplasmic domains.
Cell 1992;68(6):1051-60.
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1992: Teixidó J; Parker C M; Kassner P D; Hemler M E
Functional and structural analysis of VLA-4 integrin alpha 4 subunit cleavage.
The Journal of biological chemistry 1992;267(3):1786-91.
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1992: Hemler M E; Kassner P D; Chan B M
Functional roles for integrin alpha subunit cytoplasmic domains.
Cold Spring Harbor symposia on quantitative biology 1992;57():213-20.
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1992: Kassner P D; Teixido J; Chan B M; Parker C M; Hemler M E
Analyses of VLA-4 structure and function.
Advances in experimental medicine and biology 1992;323():163-70.
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1991: Neuhaus H; Hu M C; Hemler M E; Takada Y; Holzmann B; Weissman I L
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
The Journal of cell biology 1991;115(4):1149-58.
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1991: Schiro J A; Chan B M; Roswit W T; Kassner P D; Pentland A P; Hemler M E; Eisen A Z; Kupper T S
Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells.
Cell 1991;67(2):403-10.
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1991: Takada Y; Murphy E; Pil P; Chen C; Ginsberg M H; Hemler M E
Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen.
The Journal of cell biology 1991;115(1):257-66.
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1991: Chan B M; Wong J G; Rao A; Hemler M E
T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(2):398-404.
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1991: Pulido R; Elices M J; Campanero M R; Osborn L; Schiffer S; García-Pardo A; Lobb R; Hemler M E; Sánchez-Madrid F
Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopes.
The Journal of biological chemistry 1991;266(16):10241-5.
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1991: Chan B M; Matsuura N; Takada Y; Zetter B R; Hemler M E
In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells.
Science (New York, N.Y.) 1991;251(5001):1600-2.
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1991: Elices M J; Urry L A; Hemler M E
Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.
The Journal of cell biology 1991;112(1):169-81.
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1990: Hemler M E; Elices M J; Chan B M; Zetter B; Matsuura N; Takada Y
Multiple ligand binding functions for VLA-2 (alpha 2 beta 1) and VLA-3 (alpha 3 beta 1) in the integrin family.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1990;32(3):229-38.
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1990: Ramaswamy H; Hemler M E
Cloning, primary structure and properties of a novel human integrin beta subunit.
The EMBO journal 1990;9(5):1561-8.
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1990: Hemler M E; Elices M J; Parker C; Takada Y
Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions.
Immunological reviews 1990;114():45-65.
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1990: Elices M J; Osborn L; Takada Y; Crouse C; Luhowskyj S; Hemler M E; Lobb R R
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.
Cell 1990;60(4):577-84.
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1990: Hemler M E
VLA proteins in the integrin family: structures, functions, and their role on leukocytes.
Annual review of immunology 1990;8():365-400.
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1989: Elices M J; Hemler M E
The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9906-10.
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1989: Kennel S J; Foote L J; Falcioni R; Sonnenberg A; Stringer C D; Crouse C; Hemler M E
Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily.
The Journal of biological chemistry 1989;264(26):15515-21.
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1989: Bank I; Hemler M; Brenner M B; Cohen D; Levy V; Belko J; Crouse C; Chess L
A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule.
Cellular immunology 1989;122(2):416-23.
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1989: Takada Y; Hemler M E
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.
The Journal of cell biology 1989;109(1):397-407.
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1989: Takada Y; Elices M J; Crouse C; Hemler M E
The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
The EMBO journal 1989;8(5):1361-8.
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1989: Hemler M E; Crouse C; Sonnenberg A
Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines.
The Journal of biological chemistry 1989;264(11):6529-35.
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1989: Heino J; Ignotz R A; Hemler M E; Crouse C; Massagué J
Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit.
The Journal of biological chemistry 1989;264(1):380-8.
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1988: Takada Y; Wayner E A; Carter W G; Hemler M E
Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimers.
Journal of cellular biochemistry 1988;37(4):385-93.
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1988: Fingerman E; Hemler M E
Regulation of proteins in the VLA cell substrate adhesion family: influence of cell growth conditions on VLA-1, VLA-2, and VLA-3 expression.
Experimental cell research 1988;177(1):132-42.
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1988: Hemler M E; Crouse C; Takada Y; Sonnenberg A
Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.
The Journal of biological chemistry 1988;263(16):7660-5.
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1988: Hemler M E
Adhesive protein receptors on hematopoietic cells.
Immunology today 1988;9(4):109-13.
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1988: Saltini C; Hemler M E; Crystal R G
T lymphocytes compartmentalized on the epithelial surface of the lower respiratory tract express the very late activation antigen complex VLA-1.
Clinical immunology and immunopathology 1988;46(2):221-33.
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1987: Hemler M E; Huang C; Takada Y; Schwarz L; Strominger J L; Clabby M L
Characterization of the cell surface heterodimer VLA-4 and related peptides.
The Journal of biological chemistry 1987;262(24):11478-85.
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1987: Hemler M E; Jacobson J G
Cell matrix adhesion-related proteins VLA-1 and VLA-2: regulation of expression on T cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(9):2941-8.
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1987: Takada Y; Strominger J L; Hemler M E
The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3239-43.
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1987: Takada Y; Huang C; Hemler M E
Fibronectin receptor structures in the VLA family of heterodimers.
Nature 1987;326(6113):607-9.
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1987: Hemler M E; Huang C; Schwarz L
The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.
The Journal of biological chemistry 1987;262(7):3300-9.
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1987: Pischel K D; Hemler M E; Huang C; Bluestein H G; Woods V L
Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(1):226-33.
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1986: Hemler M E; Glass D; Coblyn J S; Jacobson J G
Very late activation antigens on rheumatoid synovial fluid T lymphocytes. Association with stages of T cell activation.
The Journal of clinical investigation 1986;78(3):696-702.
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1985: Hemler M E; Jacobson J G; Strominger J L
Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells.
The Journal of biological chemistry 1985;260(28):15246-52.
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1985: Hafler D A; Hemler M E; Christenson L; Williams J M; Shapiro H M; Strom T B; Strominger J L; Weiner H L
Investigation of in vivo activated T cells in multiple sclerosis and inflammatory central nervous system diseases.
Clinical immunology and immunopathology 1985;37(2):163-71.
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1985: Hemler M E; Jacobson J G; Brenner M B; Mann D; Strominger J L
VLA-1: a T cell surface antigen which defines a novel late stage of human T cell activation.
European journal of immunology 1985;15(5):502-8.
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1984: Hemler M E; Sanchez-Madrid F; Flotte T J; Krensky A M; Burakoff S J; Bhan A K; Springer T A; Strominger J L
Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(6):3011-8.
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1984: Peters P M; Kamarck M E; Hemler M E; Strominger J L; Ruddle F H
Genetic and biochemical characterization of human lymphocyte cell surface antigens. The A-1A5 and A-3A4 determinants.
The Journal of experimental medicine 1984;159(5):1441-54.
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1984: Hemler M E; Brenner M B; McLean J M; Strominger J L
Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(7):2172-5.
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1983: Hemler M E; Malissen B; Rebai N; Liabeuf A; Mawas C; Kourilsky F M; Strominger J L
A 55,000 Mr surface antigen on activated human T lymphocytes defined by a monoclonal antibody.
Human immunology 1983;8(2):153-65.
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1983: Haynes B F; Harden E A; Telen M J; Hemler M E; Strominger J L; Palker T J; Scearce R M; Eisenbarth G S
Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(3):1195-200.
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1983: Hemler M E; Ware C F; Strominger J L
Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(1):334-40.
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1983: Burakoff S J; Clayberger C; Hemler M; Krensky A M; Reiss C S; Robbins E; Sanchez-Madrid F; Springer T A; Strominger J L; Ware C F
Cytotoxic T cells directed against HLA-DR antigens and their surface proteins.
Diagnostic immunology 1983;1(3):116-9.
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1982: Hemler M E; Strominger J L
Monoclonal antibodies reacting with immunogenic mycoplasma proteins present in human hematopoietic cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(6):2734-8.
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1982: Peters P G; Kamarck M E; Hemler M E; Strominger J L; Ruddle F H
Genetic and biochemical characterization of a human surface determinant on somatic cell hybrids: the 4F2 antigen.
Somatic cell genetics 1982;8(6):825-34.
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1982: Hemler M E; Strominger J L
Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(2):623-8.
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1982: Haynes B F; Reisner E G; Hemler M E; Strominger J L; Eisenbarth G S
Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.
Human immunology 1982;4(4):273-85.
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1981: Haynes B F; Hemler M; Cotner T; Mann D L; Eisenbarth G S; Strominger J L; Fauci A S
Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(1):347-51.
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1981: Irigoyen O H; Rizzolo P V; Thomas Y; Hemler M E; Shen H H; Friedman S M; Strominger J L; Chess L
Dissection of distinct human immunoregulatory T-cell subsets by a monoclonal antibody recognizing a cell surface antigen with wide tissue distribution.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(5):3160-4.
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1981: Haynes B F; Hemler M E; Mann D L; Eisenbarth G S; Shelhamer J; Mostowski H S; Thomas C A; Strominger J L; Fauci A S
Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1981;126(4):1409-14.
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1981: Cotner T; Hemler M; Strominger J L
Human T cell proteins recognized by rabbit heteroantisera and monoclonal antibodies.
International journal of immunopharmacology 1981;3(3):255-68.
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1980: Reiss C S; Hemler M E; Englehard V H; Mier J W; Strominger J L; Burakoff S J
Development and characterization of allospecific long-term human cytolytic T-cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(9):5432-6.
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1980: Hemler M E; Lands W E
Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.
The Journal of biological chemistry 1980;255(13):6253-61.
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1980: Hemler M E; Lands W E
Protection of cyclooxygenase activity during heme-induced destabilization.
Archives of biochemistry and biophysics 1980;201(2):586-93.
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1980: Haynes B F; Mann D L; Hemler M E; Schroer J A; Shelhamer J H; Eisenbarth G S; Strominger J L; Thomas C A; Mostowski H S; Fauci A S
Characterization of a monoclonal antibody that defines an immunoregulatory T cell subset for immunoglobulin synthesis in humans.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2914-8.
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