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alex almasan

Research Profile

Chemicals & Drugs

Anatomy

Physiology

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Ning Zhou; alex almasan; Robert Dreicer; Jeffrey A Ecsedy; Daniel Lindner; Maria C Mir; Yvonne Parker; Kamini Singh; Bin T Teh; Zhongfa Zhang; Donna E Hansel
The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.
Payel Chatterjee; Gaurav S Choudhary; Jay Ciezki; Warren D Heston; Eric A Klein; Arishya Sharma; Kamini Singh; alex almasan
PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.
Jia Qiu; Kamini Singh; Samjhana Thapalaya; Cynthia Tsien; Conrad Chris Weihl; George Dubyak; Bijan Eghtesad; Xiaoming Fu; Stanley L Hazen; Christine McDonald; Sathyamangla V Naga Prasad; Arvind Narayanan; alex almasan; James K Ching; Srinivasan Dasarathy
Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.

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2013: Ning Zhou; alex almasan; Robert Dreicer; Jeffrey A Ecsedy; Daniel Lindner; Maria C Mir; Yvonne Parker; Kamini Singh; Bin T Teh; Zhongfa Zhang; Donna E Hansel
The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(7):1717-28.
2013: Payel Chatterjee; Gaurav S Choudhary; Jay Ciezki; Warren D Heston; Eric A Klein; Arishya Sharma; Kamini Singh; alex almasan
PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.
PloS one 2013;8(4):e60408.
2012: Jia Qiu; Kamini Singh; Samjhana Thapalaya; Cynthia Tsien; Conrad Chris Weihl; George Dubyak; Bijan Eghtesad; Xiaoming Fu; Stanley L Hazen; Christine McDonald; Sathyamangla V Naga Prasad; Arvind Narayanan; alex almasan; James K Ching; Srinivasan Dasarathy
Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.
American journal of physiology. Endocrinology and metabolism 2012;303(8):E983-93.
2012: Daniel J Klionsky; Jochen Klucken; Erwin Knecht; Ben C B Ko; Jan C Koch; Hiroshi Koga; Jae-Young Koh; Young Ho Koh; Masato Koike; Masaaki Komatsu; Eiki Kominami; Hee Jeong Kong; Wei-Jia Kong; Viktor I Korolchuk; Yaichiro Kotake; Michael I Koukourakis; Juan B Kouri Flores; Attila L Kovács; Claudine Kraft; Dimitri Krainc; Helmut Krämer; Carole Kretz-Remy; Anna M Krichevsky; Guido Kroemer; Rejko Krüger; Oleg Krut; Nicholas T Ktistakis; Chia-Yi Kuan; Roza Kucharczyk; Ashok Kumar; Raj Kumar; Sharad Kumar; Mondira Kundu; Hsing-Jien Kung; Tino Kurz; Ho Jeong Kwon; Albert R La Spada; Frank Lafont; Trond Lamark; Jacques Landry; Jon D Lane; Pierre Lapaquette; Jocelyn F Laporte; Lajos László; Sergio Lavandero; Josée N Lavoie; Robert Layfield; Pedro A Lazo; Laurent Le Cam; Weidong Le; Daniel J Ledbetter; Alvin J X Lee; Byung-Wan Lee; Gyun Min Lee; Jongdae Lee; Ju-Hyun Lee; Michael Lee; Myung-Shik Lee; Sug Hyung Lee; Christiaan Leeuwenburgh; Patrick Legembre; Renaud Legouis; Michael Lehmann; Huan-Yao Lei; Qun-Ying Lei; David A Leib; José Leiro; John J Lemasters; Antoinette Lemoine; Maciej S Lesniak; Dina Lev; Victor V Levenson; Beth Levine; Efrat Levy; Faqiang Li; Jun-Lin Li; Lian Li; Sheng Li; Weijie Li; Xue-Jun Li; Yan-bo Li; Yi-Ping Li; Chengyu Liang; Qiangrong Liang; Yung-Feng Liao; Pawel P Liberski; Andrew P Lieberman; Hyunjung J Lim; Kyu Lim; Kah-Leong Lim; Chiou-Feng Lin; Fu-Cheng Lin; Jian Lin; Jiandie D Lin; Kui Lin; Weei-Chin Lin; Wan-Wan Lin; Yi-Ling Lin; Rafael Linden; Paul Lingor; Jennifer Lippincott-Schwartz; Michael P Lisanti; Paloma B Liton; Bo Liu; Chun-Feng Liu; Kaiyu Liu; Leyuan Liu; Qiong A Liu; Wei Liu; Yule Liu; Young-Chau Liu; Richard A Lockshin; Chun-Nam Lok; Sagar Lonial; Benjamin Loos; Gabriel Lopez-Berestein; Carlos López-Otín; Laura Lossi; Michael T Lotze; Peter Lőw; Binfeng Lu; Bingwei Lu; Bo Lu; Zhen Lu; Frédéric Luciano; Nicholas W Lukacs; Anders H Lund; Melinda A Lynch-Day; Yong Ma; Fernando Macian; Jeffrey P MacKeigan; Kay F Macleod; Frank Madeo; Luigi Maiuri; Maria Chiara Maiuri; Davide Malagoli; May Christine V Malicdan; Walter Malorni; Na Man; Eva-Maria Mandelkow; Stéphen Manon; Irena Manov; Kai Mao; Xiang Mao; Zixu Mao; Philippe Marambaud; Daniela Marazziti; Yves L Marcel; Katie Marchbank; Piero Marchetti; Stefan Marciniak; Mateus Marcondes; Mohsen Mardi; Gabriella Marfe; Guillermo Mariño; Maria Markaki; Mark R Marten; Seamus J Martin; Camille Martinand-Mari; Wim Martinet; Marta Martinez-Vicente; Matilde Masini; Paola Matarrese; Saburo Matsuo; Raffaele Matteoni; Andreas Mayer; Nathalie M Mazure; David J McConkey; Melanie J McConnell; Catherine McDermott; Christine McDonald; Gerald M McInerney; Sharon L McKenna; BethAnn McLaughlin; Pamela J McLean; Christopher R McMaster; G Angus McQuibban; Alfred J Meijer; Miriam H Meisler; Alicia Meléndez; Thomas J Melia; Gerry Melino; Maria A Mena; Javier A Menendez; Rubem F S Menna-Barreto; Manoj B Menon; Fiona M Menzies; Carol A Mercer; Adalberto Merighi; Diane E Merry; Stefania Meschini; Christian G Meyer; Thomas F Meyer; Chao-Yu Miao; Jun-Ying Miao; Paul A M Michels; Carine Michiels; Dalibor Mijaljica; Ana Milojkovic; Saverio Minucci; Clelia Miracco; Cindy Miranti; Ioannis Mitroulis; Keisuke Miyazawa; Noboru Mizushima; Baharia Mograbi; Simin Mohseni; Xavier Molero; Bertrand Mollereau; Faustino Mollinedo; Takashi Momoi; Iryna Monastyrska; Martha M Monick; Mervyn Monteiro; Michael N Moore; Rodrigo Mora; Kevin Moreau; Paula I Moreira; Yuji Moriyasu; Jorge Moscat; Serge Mostowy; Jeremy C Mottram; Tomasz Motyl; Charbel E-H Moussa; Sylviane Muller; Sylke Müller; Karl Münger; Christian Münz; Leon O Murphy; Maureen E Murphy; Antonio Musarò; Indira Mysorekar; Eiichiro Nagata; Kazuhiro Nagata; Aimable Nahimana; Usha Nair; Toshiyuki Nakagawa; Kiichi Nakahira; Hiroyasu Nakano; Hitoshi Nakatogawa; Meera Nanjundan; Naweed I Naqvi; Derek P Narendra; Masashi Narita; Miguel Navarro; Steffan Nawrocki; Taras Y Nazarko; Andriy Nemchenko; Mihai G Netea; Thomas P Neufeld; Paul A Ney; Ioannis P Nezis; Huu Phuc Nguyen; Daotai Nie; Ichizo Nishino; Corey Nislow; Ralph A Nixon; Takeshi Noda; Angelika A Noegel; Anna Nogalska; Satoru Noguchi; Lucia Notterpek; Ivana Novak; Tomoyoshi Nozaki; Nobuyuki Nukina; Thorsten Nürnberger; Beat Nyfeler; Keisuke Obara; Terry D Oberley; Salvatore Oddo; Michinaga Ogawa; Toya Ohashi; Koji Okamoto; Nancy L Oleinick; F Javier Oliver; Laura J Olsen; Stefan Olsson; Onya Opota; Timothy F Osborne; Gary K Ostrander; Kinya Otsu; Jing-hsiung James Ou; Mireille Ouimet; Michael Overholtzer; Bulent Ozpolat; Paolo Paganetti; Ugo Pagnini; Nicolas Pallet; Glen E Palmer; Camilla Palumbo; Tianhong Pan; Theocharis Panaretakis; Udai Bhan Pandey; Zuzana Papackova; Issidora Papassideri; Irmgard Paris; Junsoo Park; Ohkmae K Park; Jan B Parys; Katherine R Parzych; Susann Patschan; Cam Patterson; Sophie Pattingre; John M Pawelek; Jianxin Peng; David H Perlmutter; Ida Perrotta; George Perry; Shazib Pervaiz; Matthias Peter; Godefridus J Peters; Morten Petersen; Goran Petrovski; James M Phang; Mauro Piacentini; Philippe Pierre; Valérie Pierrefite-Carle; Gérard Pierron; Ronit Pinkas-Kramarski; Antonio Piras; Natik Piri; Leonidas C Platanias; Stefanie Pöggeler; Marc Poirot; Angelo Poletti; Christian Poüs; Mercedes Pozuelo-Rubio; Mette Prætorius-Ibba; Anil Prasad; Mark Prescott; Muriel Priault; Nathalie Produit-Zengaffinen; Ann Progulske-Fox; Tassula Proikas-Cezanne; Serge Przedborski; Karin Przyklenk; Rosa Puertollano; Julien Puyal; Shu-Bing Qian; Liang Qin; Zheng-Hong Qin; Susan E Quaggin; Nina Raben; Hannah Rabinowich; Simon W Rabkin; Irfan Rahman; Abdelhaq Rami; Georg Ramm; Glenn Randall; Felix Randow; V Ashutosh Rao; Jeffrey C Rathmell; Brinda Ravikumar; Swapan K Ray; Bruce H Reed; John C Reed; Fulvio Reggiori; Anne Régnier-Vigouroux; Andreas S Reichert; John J Reiners; Russel J Reiter; Jun Ren; José L Revuelta; Christopher J Rhodes; Konstantinos Ritis; Elizete Rizzo; Jeffrey Robbins; Michel Roberge; Hernan Roca; Maria C Roccheri; Stephane Rocchi; H Peter Rodemann; Santiago Rodríguez de Córdoba; Bärbel Rohrer; Igor B Roninson; Kirill Rosen; Magdalena M Rost-Roszkowska; Mustapha Rouis; Kasper M A Rouschop; Francesca Rovetta; Brian P Rubin; David C Rubinsztein; Klaus Ruckdeschel; Edmund B Rucker; Assaf Rudich; Emil Rudolf; Nelson Ruiz-Opazo; Rossella Russo; Tor Erik Rusten; Kevin M Ryan; Stefan W Ryter; David M Sabatini; Junichi Sadoshima; Tapas Saha; Tatsuya Saitoh; Hiroshi Sakagami; Yasuyoshi Sakai; Ghasem Hoseini Salekdeh; Paolo Salomoni; Paul M Salvaterra; Guy Salvesen; Rosa Salvioli; Anthony M J Sanchez; José A Sánchez-Alcázar; Ricardo Sánchez-Prieto; Marco Sandri; Uma Sankar; Poonam Sansanwal; Laura Santambrogio; Shweta Saran; Sovan Sarkar; Minnie Sarwal; Chihiro Sasakawa; Ausra Sasnauskiene; Miklós Sass; Ken Sato; Miyuki Sato; Anthony H V Schapira; Michael Scharl; Hermann M Schätzl; Wiep Scheper; Stefano Schiaffino; Claudio Schneider; Marion E Schneider; Regine Schneider-Stock; Patricia V Schoenlein; Daniel F Schorderet; Christoph Schüller; Gary K Schwartz; Luca Scorrano; Linda Sealy; Per O Seglen; Juan Segura-Aguilar; Iban Seiliez; Oleksandr Seleverstov; Christian Sell; Jong Bok Seo; Duska Separovic; Vijayasaradhi Setaluri; Takao Setoguchi; Carmine Settembre; John J Shacka; Mala Shanmugam; Irving M Shapiro; Eitan Shaulian; Reuben J Shaw; James H Shelhamer; Han-Ming Shen; Wei-Chiang Shen; Zu-Hang Sheng; Yang Shi; Kenichi Shibuya; Yoshihiro Shidoji; Jeng-Jer Shieh; Chwen-Ming Shih; Yohta Shimada; Shigeomi Shimizu; Takahiro Shintani; Orian S Shirihai; Gordon C Shore; Andriy A Sibirny; Stan B Sidhu; Beata Sikorska; Elaine Silva-Zacarin; Elaine C M Silva-Zacarin; Alison Simmons; Anna Katharina Simon; Hans-Uwe Simon; Cristiano Simone; Anne Simonsen; David A Sinclair; Rajat Singh; Debasish Sinha; Frank A Sinicrope; Agnieszka Sirko; Parco M Siu; Efthimios Sivridis; Vojtech Skop; Vladimir P Skulachev; Ruth S Slack; Soraya S Smaili; Duncan Smith; Maria S Soengas; Thierry Soldati; Xueqin Song; Anil K Sood; Tuck Wah Soong; Federica Sotgia; Stephen A Spector; Claudia D Spies; Wolfdieter Springer; Srinivasa M Srinivasula; Leonidas Stefanis; Joan S Steffan; Ruediger Stendel; Harald Stenmark; Anastasis Stephanou; Stephan T Stern; Cinthya Sternberg; Björn Stork; Peter Strålfors; Carlos S Subauste; Xinbing Sui; David Sulzer; Jiaren Sun; Shi-Yong Sun; Zhi-Jun Sun; Joseph J Y Sung; Kuninori Suzuki; Toshihiko Suzuki; Michele S Swanson; Charles Swanton; Sean T Sweeney; Lai-King Sy; Gyorgy Szabadkai; Ira Tabas; Heinrich Taegtmeyer; Marco Tafani; Krisztina Takács-Vellai; Yoshitaka Takano; Kaoru Takegawa; Genzou Takemura; Fumihiko Takeshita; Nicholas J Talbot; Kevin S W Tan; Keiji Tanaka; Kozo Tanaka; Daolin Tang; Dingzhong Tang; Isei Tanida; Bakhos A Tannous; Nektarios Tavernarakis; Gregory A Taylor; Graham S Taylor; J Paul Taylor; Lance S Terada; Alexei Terman; Gianluca Tettamanti; Karin Thevissen; Craig B Thompson; Andrew Thorburn; Michael Thumm; FengFeng Tian; Yuan Tian; Glauco Tocchini-Valentini; Aviva M Tolkovsky; Yasuhiko Tomino; Lars Tönges; Sharon A Tooze; Cathy Tournier; John Tower; Roberto Towns; Vladimir Trajkovic; Leonardo H Travassos; Ting-Fen Tsai; Mario P Tschan; Takeshi Tsubata; Allan Tsung; Boris Turk; Lorianne S Turner; Suresh C Tyagi; Yasuo Uchiyama; Takashi Ueno; Midori Umekawa; Rika Umemiya-Shirafuji; Vivek K Unni; Maria I Vaccaro; Enza Maria Valente; Greet Van den Berghe; Ida J van der Klei; Wouter van Doorn; Linda F van Dyk; Marjolein van Egmond; Leo A van Grunsven; Peter Vandenabeele; Wim P Vandenberghe; Ilse Vanhorebeek; Eva C Vaquero; Guillermo Velasco; Tibor Vellai; Jose Miguel Vicencio; Richard D Vierstra; Miquel Vila; Cécile Vindis; Giampietro Viola; Maria Teresa Viscomi; Olga V Voitsekhovskaja; Clarissa von Haefen; Marcela Votruba; Keiji Wada; Richard Wade-Martins; Cheryl L Walker; Craig M Walsh; Jochen Walter; Xiang-Bo Wan; Aimin Wang; Chenguang Wang; Dawei Wang; Fan Wang; Fen Wang; Guanghui Wang; Haichao Wang; Horng-Dar Wang; Hong-Gang Wang; Jin Wang; Ke Wang; Mei Wang; Richard C Wang; Xinglong Wang; Xuejun Wang; Yipeng Wang; Ying-Jan Wang; Zhen Wang; Zhinong Wang; Zhigang Charles Wang; Derick G Wansink; Diane M Ward; Hirotaka Watada; Sarah L Waters; Paul Webster; Lixin Wei; Conrad C Weihl; William A Weiss; Scott M Welford; Long-Ping Wen; Caroline A Whitehouse; J Lindsay Whitton; Alexander J Whitworth; Tom Wileman; John W Wiley; Simon Wilkinson; Dieter Willbold; Roger L Williams; Peter R Williamson; Bradly G Wouters; Chenghan Wu; Dao-Cheng Wu; William K K Wu; Andreas Wyttenbach; Ramnik J Xavier; Zhijun Xi; Pu Xia; Gengfu Xiao; Zhiping Xie; Zhonglin Xie; Da-zhi Xu; Jianzhen Xu; Liang Xu; Xiaolei Xu; Ai Yamamoto; Akitsugu Yamamoto; Shunhei Yamashina; Michiaki Yamashita; Xianghua Yan; Mitsuhiro Yanagida; Dun-Sheng Yang; Elizabeth Yang; Jin-Ming Yang; Shi Yu Yang; Wannian Yang; Wei Yuan Yang; Zhifen Yang; Meng-Chao Yao; Tso-Pang Yao; Behzad Yeganeh; Wei-Lien Yen; Jia-jing Yin; Xiao-Ming Yin; Ook-Joon Yoo; Gyesoon Yoon; Seung-Yong Yoon; Tomohiro Yorimitsu; Yuko Yoshikawa; Tamotsu Yoshimori; Kohki Yoshimoto; Ho Jin You; Richard J Youle; Anas Younes; Li Yu; Long Yu; Seong-Woon Yu; Wai Haung Yu; Zhi-Min Yuan; Zhenyu Yue; Cheol-Heui Yun; Michisuke Yuzaki; Olga Zabirnyk; David N Zacks; Eldad Zacksenhaus; Nadia Zaffaroni; Zahra Zakeri; Herbert J Zeh; Scott O Zeitlin; Hong Zhang; Hui-Ling Zhang; Jianhua Zhang; Jing-Pu Zhang; Lin Zhang; Long Zhang; Ming-Yong Zhang; Xu Dong Zhang; Mantong Zhao; Ying Zhao; Yi-Fang Zhao; Zhizhuang J Zhao; Xiaoxiang Zheng; Boris Zhivotovsky; Qing Zhong; Cong-Zhao Zhou; Changlian Zhu; Wei-Guo Zhu; Xiongwei Zhu; Xiao-Feng Zhu; Yuangang Zhu; Teresa Zoladek; Wei-Xing Zong; Antonio Zorzano; Jürgen Zschocke; Fabio C Abdalla; Hagai Abeliovich; Robert T Abraham; Abraham Acevedo-Arozena; Khosrow Adeli; Lotta Agholme; Maria Agnello; Patrizia Agostinis; Julio A Aguirre-Ghiso; Hyung Jun Ahn; Ouardia Ait-Mohamed; Slimane Ait-Si-Ali; Takahiko Akematsu; Shizuo Akira; Matthew L Albert; Roger L Albin; Javier Alegre-Abarrategui; Maria Francesca Aleo; Mehrdad Alirezaei; alex almasan; Maylin Almonte-Becerril; Hesham M Al-Younes; Munir A Al-Zeer; Atsuo Amano; Ravi Amaravadi; Shoba Amarnath; Amal O Amer; Vellareddy Anantharam; Nathalie Andrieu-Abadie; David K Ann; Shailendra Anoopkumar-Dukie; Hiroshi Aoki; Nadezda Apostolova; Patrick Auberger; Misuzu Baba; Steven K Backues; Eric H Baehrecke; Ben A Bahr; Xue-Yuan Bai; Yannick Bailly; Robert Baiocchi; Giulia Baldini; Walter Balduini; Andrea Ballabio; Bruce A Bamber; Edward T W Bampton; Gábor Bánhegyi; Clinton R Bartholomew; Diane C Bassham; Robert C Bast; Henri Batoko; Boon-Huat Bay; Isabelle Beau; Daniel M Béchet; Thomas J Begley; Christian Behl; Christian Behrends; Soumeya Bekri; Bryan Bellaire; Linda J Bendall; Luca Benetti; Laura Berliocchi; Henri Bernardi; Francesca Bernassola; Sébastien Besteiro; Ingrid Bhatia-Kissova; Xiaoning Bi; Martine Biard-Piechaczyk; Janice S Blum; Lawrence H Boise; Paolo Bonaldo; David L Boone; Beat C Bornhauser; Karina R Bortoluci; Ioannis Bossis; Frédéric Bost; Jean-Pierre Bourquin; Patricia Boya; Michaël Boyer-Guittaut; Peter V Bozhkov; Nathan R Brady; Claudio Brancolini; Andreas Brech; Jay E Brenman; Ana Brennand; Emery H Bresnick; Patrick Brest; Dave Bridges; Molly L Bristol; Paul S Brookes; Eric J Brown; John H Brumell; Nicola Brunetti-Pierri; Ulf T Brunk; Dennis E Bulman; Scott J Bultman; Geert Bultynck; Lena F Burbulla; Wilfried Bursch; Jonathan P Butchar; Wanda Buzgariu; Sergio P Bydlowski; Ken Cadwell; Monika Cahová; Dongsheng Cai; Jiyang Cai; Qian Cai; Bruno Calabretta; Javier Calvo-Garrido; Nadine Camougrand; Michelangelo Campanella; Jenny Campos-Salinas; Eleonora Candi; Lizhi Cao; Allan B Caplan; Simon R Carding; Sandra M Cardoso; Jennifer Carew; Cathleen R Carlin; Virginie Carmignac; Leticia A M Carneiro; Serena Carra; Rosario A Caruso; Giorgio Casari; Caty Casas; Roberta Castino; Eduardo Cebollero; Francesco Cecconi; Jean Celli; Hassan Chaachouay; Han-Jung Chae; Chee-Yin Chai; David C Chan; Edmond Y Chan; Raymond Chuen-Chung Chang; Chi-Ming Che; Ching-Chow Chen; Guang-Chao Chen; Guo-Qiang Chen; Min Chen; Quan Chen; Steve S-L Chen; WenLi Chen; Xi Chen; Xiangmei Chen; Xiequn Chen; Yingyu Chen; Yongqiang Chen; Ye-Guang Chen; Yu-Jen Chen; Zhixiang Chen; Alan Cheng; Christopher H K Cheng; Yan Cheng; Heesun Cheong; Jae-Ho Cheong; Sara Cherry; Russ Chess-Williams; Zelda H Cheung; Eric Chevet; Hui-Ling Chiang; Roberto Chiarelli; Tomoki Chiba; Lih-Shen Chin; Shih-Hwa Chiou; Francis V Chisari; Chi Hin Cho; Dong-Hyung Cho; Augustine M K Choi; DooSeok Choi; Kyeong Sook Choi; Mary E Choi; Salem Chouaib; Divaker Choubey; Vinay Choubey; Charleen T Chu; Tsung-Hsien Chuang; Sheau-Huei Chueh; Taehoon Chun; Yong-Joon Chwae; Mee-Len Chye; Roberto Ciarcia; Maria R Ciriolo; Michael J Clague; Robert S B Clark; Peter G H Clarke; Robert Clarke; Patrice Codogno; Hilary A Coller; María I Colombo; Sergio Comincini; Maria Condello; Fabrizio Condorelli; Mark R Cookson; Graham H Coombs; Isabelle Coppens; Ramon Corbalan; Pascale Cossart; Paola Costelli; Safia Costes; Ana Coto-Montes; Eduardo Couve; Fraser P Coxon; James M Cregg; José L Crespo; Marianne J Cronjé; Ana Maria Cuervo; Joseph J Cullen; Mark J Czaja; Marcello D'Amelio; Arlette Darfeuille-Michaud; Lester M Davids; Faith E Davies; Massimo De Felici; John F de Groot; Cornelis A M de Haan; Luisa De Martino; Angelo De Milito; Vincenzo De Tata; Jayanta Debnath; Alexei Degterev; Benjamin Dehay; Lea M D Delbridge; Francesca Demarchi; Yi Zhen Deng; Jörn Dengjel; Paul Dent; Donna Denton; Vojo Deretic; Shyamal D Desai; Rodney J Devenish; Mario Di Gioacchino; Gilbert Di Paolo; Chiara Di Pietro; Guillermo Díaz-Araya; Inés Díaz-Laviada; Maria T Diaz-Meco; Javier Diaz-Nido; Ivan Dikic; Savithramma P Dinesh-Kumar; Wen-Xing Ding; Clark W Distelhorst; Abhinav Diwan; Mojgan Djavaheri-Mergny; Svetlana Dokudovskaya; Zheng Dong; Frank C Dorsey; Victor Dosenko; James Dowling; Stephen Doxsey; Marlène Dreux; Mark E Drew; Qiuhong Duan; Michel A Duchosal; Karen Duff; Isabelle Dugail; Madeleine Durbeej; Michael Duszenko; Charles L Edelstein; Aimee L Edinger; Gustavo Egea; Ludwig Eichinger; N Tony Eissa; Suhendan Ekmekcioglu; Zvulun Elazar; Wafik S El-Deiry; Mohamed Elgendy; Lisa M Ellerby; Kai Er Eng; Anna-Mart Engelbrecht; Simone Engelender; Jekaterina Erenpreisa; Ricardo Escalante; Audrey Esclatine; Eeva-Liisa Eskelinen; Lucile Espert; Virginia Espina; Huizhou Fan; Jia Fan; Qi-Wen Fan; Zhen Fan; Shengyun Fang; Yongqi Fang; Manolis Fanto; Alessandro Fanzani; Thomas Farkas; Jean-Claude Farré; Mathias Faure; Marcus Fechheimer; Carl G Feng; Jian Feng; Qili Feng; Youji Feng; László Fésüs; Ralph Feuer; Maria E Figueiredo-Pereira; Gian Maria Fimia; Diane C Fingar; Steven Finkbeiner; TOREN FINKEL; Kim D Finley; Filomena Fiorito; Edward A Fisher; Paul B Fisher; Marc Flajolet; Maria L Florez-McClure; Salvatore Florio; Edward A Fon; Francesco Fornai; Franco Fortunato; Rati Fotedar; Daniel H Fowler; Howard S Fox; Rodrigo Franco; Lisa B Frankel; Marc Fransen; José M Fuentes; Juan Fueyo; Jun Fujii; Kozo Fujisaki; Eriko Fujita; Mitsunori Fukuda; Ruth H Furukawa; Matthias Gaestel; Philippe Gailly; Malgorzata Gajewska; Brigitte Galliot; Vincent Galy; Subramaniam Ganesh; Barry Ganetzky; Ian G Ganley; Fen-Biao Gao; George F Gao; Jinming Gao; Lorena Garcia; Guillermo Garcia-Manero; Mikel Garcia-Marcos; Marjan Garmyn; Andrei L Gartel; Evelina Gatti; Mathias Gautel; Thomas R Gawriluk; Matthew E Gegg; Jiefei Geng; Marc Germain; Jason E Gestwicki; David A Gewirtz; Saeid Ghavami; Pradipta Ghosh; Anna M Giammarioli; Alexandra N Giatromanolaki; Spencer B Gibson; Robert W Gilkerson; Michael L Ginger; Ebru Goncu; Céline Gongora; Claudio D Gonzalez; Ramon Gonzalez; Cristina González-Estévez; Rosa Ana González-Polo; Elena Gonzalez-Rey; Nikolai V Gorbunov; Sharon Gorski; Sandro Goruppi; Roberta A Gottlieb; Devrim Gozuacik; Giovanna Elvira Granato; Gary D Grant; Kim N Green; Aleš Gregorc; Frédéric Gros; Charles Grose; Thomas W Grunt; Philippe Gual; Jun-Lin Guan; Kun-Liang Guan; Sylvie M Guichard; Anna S Gukovskaya; Ilya Gukovsky; Jan Gunst; Asa B Gustafsson; Andrew J Halayko; Amber N Hale; Sandra K Halonen; Maho Hamasaki; Feng Han; Ting Han; Michael K Hancock; Malene Hansen; Hisashi Harada; Masaru Harada; Stefan E Hardt; J Wade Harper; Adrian L Harris; James Harris; Steven D Harris; Marie-Joseé Hébert; Kim A Heidenreich; Miep H Helfrich; Gudmundur V Helgason; Elizabeth P Henske; Brian Herman; Paul K Herman; Claudio Hetz; Sabine Hilfiker; Joseph A Hill; Lynne J Hocking; Paul Hofman; Thomas G Hofmann; Jörg Höhfeld; Tessa L Holyoake; Ming-Huang Hong; David A Hood; Gökhan S Hotamisligil; Ewout J Houwerzijl; Maria Høyer-Hansen; Bingren Hu; Chien-An A Hu; Hong-Ming Hu; Ya Hua; Canhua Huang; Ju Huang; Shengbing Huang; Wei-Pang Huang; Tobias B Huber; Won-Ki Huh; Tai-Ho Hung; Ted R Hupp; Gang Min Hur; James B Hurley; Sabah N A Hussain; Patrick J Hussey; Jung Jin Hwang; Seungmin Hwang; Atsuhiro Ichihara; Shirin Ilkhanizadeh; Ken Inoki; Takeshi Into; Valentina Iovane; Juan L Iovanna; Nancy Y Ip; Yoshitaka Isaka; Hiroyuki Ishida; Ciro Isidoro; Ken-ichi Isobe; Akiko Iwasaki; Marta Izquierdo; Yotaro Izumi; Panu M Jaakkola; Marja Jäättelä; George R Jackson; William T Jackson; Bassam Janji; Marina Jendrach; Ju-Hong Jeon; Eui-Bae Jeung; Hong Jiang; Hongchi Jiang; Jean X Jiang; Ming Jiang; Qing Jiang; Xuejun Jiang; Xuejun Jiang; Alberto Jiménez; Meiyan Jin; Shengkan Jin; Cheol O Joe; Terje Johansen; Daniel E Johnson; Gail V W Johnson; Nicola L Jones; Bertrand Joseph; Suresh K Joseph; Annie M Joubert; Gábor Juhász; Lucienne Juillerat-Jeanneret; Chang Hwa Jung; Yong-Keun Jung; Kai Kaarniranta; Allen Kaasik; Tomohiro Kabuta; Motoni Kadowaki; Katarina Kagedal; Yoshiaki Kamada; Vitaliy O Kaminskyy; Harm H Kampinga; Hiromitsu Kanamori; Chanhee Kang; Khong Bee Kang; Kwang Il Kang; Rui Kang; Yoon-A Kang; Tomotake Kanki; Thirumala-Devi Kanneganti; Haruo Kanno; Arthi Kanthasamy; Anumantha G Kanthasamy; Vassiliki Karantza; Gur P Kaushal; Susmita Kaushik; Yoshinori Kawazoe; Po-Yuan Ke; John H Kehrl; Ameeta Kelekar; Claus Kerkhoff; David Kessel; Hany Khalil; Jan A K W Kiel; Amy A Kiger; Akio Kihara; Do-Hyung Kim; Dong-Hou Kim; Deok Ryong Kim; Eun-Kyoung Kim; Hyung-Ryong Kim; Jin Cheon Kim; Jeong Hun Kim; John K Kim; Jae-Sung Kim; Peter K Kim; Seong Who Kim; Yonghyun Kim; Yong-Sun Kim; Adi Kimchi; Alec C Kimmelman; Jason S King; Timothy J Kinsella; Vladimir Kirkin; Lorrie A Kirshenbaum; Katsuhiko Kitamoto; Kaio Kitazato; Ludger Klein; Walter T Klimecki; Giuseppe Arancia; John P Aris; Katsuhiko Asanuma; Nana Y O Asare; Hisashi Ashida; Valerie Askanas; David S Askew; Henry N Ginsberg; Jakub Golab; Michael S Goligorsky; Pierre Golstein; Candelaria Gomez-Manzano; Makoto Hashimoto; Jeffrey A Haspel; Shin-ichiro Hayashi; Lori A Hazelhurst; Congcong He; You-Wen He; Brian Zuckerbraun
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy 2012;8(4):445-544.
2012: Kamini Singh; Judith A Drazba; Shigemi Matsuyama; alex almasan
Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress.
Autophagy 2012;8(2):236-51.
2012: O Bucur; R Khosravi-Far; A L Stancu; alex almasan
Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications.
Cell death & disease 2012;3():e263.
2011: Juraj Bodo; Jaroslaw P Maciejewski; Jan Sedlak; alex almasan; Eric D Hsi
HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells.
Apoptosis : an international journal on programmed cell death 2011;16(9):914-23.
2011: Niloufer Khan; Mohammad K Khan; alex almasan; Arun D Singh; Roger Macklis
The evolving role of radiation therapy in the management of malignant melanoma.
International journal of radiation oncology, biology, physics 2011;80(3):645-54.
2011: Mohammad K Khan; Niloufer Khan; alex almasan; Roger M Macklis
Future of radiation therapy for malignant melanoma in an era of newer, more effective biological agents.
OncoTargets and therapy 2011;4():137-48.
2009: Nickolay Neznanov; Anton V Gorbachev; Lubov Neznanova; Andrei P Komarov; Katerina V Gurova; Alexander V Gasparian; Amiya K Banerjee; alex almasan; Robert L Fairchild; Andrei V Gudkov
Anti-malaria drug blocks proteotoxic stress response: anti-cancer implications.
Cell cycle (Georgetown, Tex.) 2009;8(23):3960-70.
2009: Jean Boutros; alex almasan
Combining 2-deoxy-D-glucose with electron transport chain blockers: a double-edged sword.
Cancer biology & therapy 2009;8(13):1237-8.
2008: Dragos Plesca; Suparna Mazumder; Vivian Gama; Shigemi Matsuyama; alex almasan
A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron.
The Journal of biological chemistry 2008;283(45):30796-803.
2008: Damodar Gupta; Meredith Crosby; alex almasan; Roger M Macklis
Regulation of CD20 expression by radiation-induced changes in intracellular redox status.
Free radical biology & medicine 2008;44(4):614-23.
2008: Dragos Plesca; Suparna Mazumder; alex almasan
DNA damage response and apoptosis.
Methods in enzymology 2008;446():107-22.
2008: Suparna Mazumder; Dragos Plesca; alex almasan
Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis.
Methods in molecular biology (Clifton, N.J.) 2008;414():13-21.
2007: M R Sandhya Rani; Sudha Pandalai; Jennifer Shrock; alex almasan; Richard M Ransohoff
Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007;27(9):767-79.
2007: Suparna Mazumder; Dragos Plesca; alex almasan
A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.
Cell cycle (Georgetown, Tex.) 2007;6(12):1437-42.
2007: Dragos Plesca; Meredith Crosby; Damodar Gupta; alex almasan
E2F4 function in G2: maintaining G2-arrest to prevent mitotic entry with damaged DNA.
Cell cycle (Georgetown, Tex.) 2007;6(10):1147-52.
2007: Suparna Mazumder; Dragos Plesca; Michael Kinter; alex almasan
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
Molecular and cellular biology 2007;27(9):3511-20.
2007: Subrata Ray; Sunitha Shyam; Gail Fraizer; alex almasan
S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
Molecular cancer therapeutics 2007;6(4):1368-78.
2007: Meredith Crosby; J Jacobberger; D Gupta; Roger M Macklis; alex almasan
E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma.
Oncogene 2007;26(13):1897-909.
2006: Marcela Oancea; Suparna Mazumder; Meredith Crosby; alex almasan
Apoptosis assays.
Methods in molecular medicine 2006;129():279-90.
2006: Octavian Bucur; Subrata Ray; Maria Cristina Bucur; alex almasan
APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy.
Frontiers in bioscience : a journal and virtual library 2006;11():1549-68.
2005: Swapan K Ray; O Bucur; alex almasan
Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor.
Apoptosis : an international journal on programmed cell death 2005;10(6):1411-8.
2005: Nickolay Neznanov; Konstantin Chumakov; Lubov Neznanova; alex almasan; Amiya Banerja; Andrei V Gudkov
Proteolytic cleavage of the p65-RelA subunit of NF-kappaB during poliovirus infection.
The Journal of biological chemistry 2005;280(25):24153-8.
2005: Takehiro Matsuda; alex almasan; Mariko Tomita; Kazumi Tamaki; Mika Saito; Masayuki Tadano; Hideo Yagita; Takao Ohta; Naoki Mori
Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.
The Journal of general virology 2005;86(Pt 4):1055-65.
2005: Suzy A A Comhair; Weiling Xu; Sudakshina Ghosh; Frederik B J M Thunnissen; alex almasan; William J Calhoun; Allison J Janocha; Lemin Zheng; Stanley L Hazen; Serpil C Erzurum
Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity.
The American journal of pathology 2005;166(3):663-74.
2005: Takehiro Matsuda; alex almasan; Mariko Tomita; Jun-Nosuke Uchihara; Masato Masuda; Kazuiku Ohshiro; Nobuyuki Takasu; Hideo Yagita; Takao Ohta; Naoki Mori
Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines.
Journal of virology 2005;79(3):1367-78.
2004: Meredith Crosby; alex almasan
Opposing roles of E2Fs in cell proliferation and death.
Cancer biology & therapy 2004;3(12):1208-11.
2004: Marcela Oancea; Aruna Mani; Mohamad A Hussein; alex almasan
Apoptosis of multiple myeloma.
International journal of hematology 2004;80(3):224-31.
2004: Ting Shi; Louis S Liou; Provash C Sadhukhan; Zhong-Hui Duan; Andrew C Novick; John G Hissong; alex almasan; Joseph A DiDonato
Effects of resveratrol on gene expression in renal cell carcinoma.
Cancer biology & therapy 2004;3(9):882-8.
2004: Erica L Dupree; Suparna Mazumder; alex almasan
Genotoxic stress induces expression of E2F4, leading to its association with p130 in prostate carcinoma cells.
Cancer research 2004;64(13):4390-3.
2004: Louis S Liou; Ting Shi; Zhong-Hui Duan; Provash C Sadhukhan; Sandy D Der; Andrew A Novick; John G Hissong; Marek Skacel; alex almasan; Joseph A DiDonato
Microarray gene expression profiling and analysis in renal cell carcinoma.
BMC urology 2004;4():9.
2004: Yanhua Zheng; Yong Shi; Changhai Tian; Chunsun Jiang; Haijing Jin; Jianjun Chen; alex almasan; Hong Tang; Quan Chen
Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide.
Oncogene 2004;23(6):1239-47.
2004: Suparna Mazumder; Erica L Dupree; alex almasan
A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy.
Current cancer drug targets 2004;4(1):65-75.
2004: Meredith Crosby; Marcela Oancea; alex almasan
p53 binding to target sites is dynamically regulated before and after ionizing radiation-mediated DNA damage.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2004;23(1):67-79.
2003: Mamta Chawla-Sarkar; John Anthony Bauer; Joseph A Lupica; Bei H Morrison; Zhuo Tang; Rhonda K Oates; alex almasan; Joseph A DiDonato; Ernest C Borden; Daniel J Lindner
Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.
The Journal of biological chemistry 2003;278(41):39461-9.
2003: Sofia C Masri; Mohamad H Yamani; Mary A Russell; Norman B Ratliff; Jiacheng Yang; alex almasan; Carolyn Apperson-Hansen; Jianbo Li; Randall C Starling; Patrick McCarthy; James B Young; Meredith Bond
Sustained apoptosis in human cardiac allografts despite histologic resolution of rejection.
Transplantation 2003;76(5):859-64.
2003: Subrata Ray; alex almasan
Apoptosis induction in prostate cancer cells and xenografts by combined treatment with Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11.
Cancer research 2003;63(15):4713-23.
2003: Quan Chen; Subrata Ray; Mohamad A Hussein; Gordan Srkalovic; alex almasan
Role of Apo2L/TRAIL and Bcl-2-family proteins in apoptosis of multiple myeloma.
Leukemia & lymphoma 2003;44(7):1209-14.
2003: alex almasan; Avi Ashkenazi
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy.
Cytokine & growth factor reviews 2003;14(3-4):337-48.
2003: Quan Chen; Yuh-Cherng Chai; Suparna Mazumder; C Jiang; Roger M Macklis; Guy M Chisolm; alex almasan
The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.
Cell death and differentiation 2003;10(3):323-34.
2002: Suparna Mazumder; Bendi Gong; Quan Chen; Judith A Drazba; Jeffrey C Buchsbaum; alex almasan
Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells.
Molecular and cellular biology 2002;22(7):2398-409.
2002: Bei H Morrison; John Anthony Bauer; Jiadi Hu; Ronald W Grane; Aylin M Ozdemir; Mamta Chawla-Sarkar; Bendi Gong; alex almasan; Dhan V Kalvakolanu; Daniel J Lindner
Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics.
Oncogene 2002;21(12):1882-9.
2002: Suparna Mazumder; alex almasan
Is caspase-8 a neuroendocrine lung tumor suppressor?
Cancer biology & therapy 2002;1(1):70-1.
2001: Quan Chen; Bendi Gong; Ashraf S Mahmoud-Ahmed; Aimin Zhou; Eric D Hsi; M Hussein; alex almasan
Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma.
Blood 2001;98(7):2183-92.
2000: Bendi Gong; alex almasan
Genomic organization and transcriptional regulation of human Apo2/TRAIL gene.
Biochemical and biophysical research communications 2000;278(3):747-52.
2000: Bendi Gong; alex almasan
Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells.
Cancer research 2000;60(20):5754-60.
2000: Suparna Mazumder; Bendi Gong; alex almasan
Cyclin E induction by genotoxic stress leads to apoptosis of hematopoietic cells.
Oncogene 2000;19(24):2828-35.
2000: alex almasan
Cellular commitment to radiation-induced apoptosis.
Radiation research 2000;153(3):347-50.
2000: Quan Chen; Bendi Gong; alex almasan
Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis.
Cell death and differentiation 2000;7(2):227-33.
1999: Bendi Gong; Quan Chen; Brian Endlich; Suparna Mazumder; alex almasan
Ionizing radiation-induced, Bax-mediated cell death is dependent on activation of cysteine and serine proteases.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(7):491-502.
1999: B Gong; alex almasan
Differential upregulation of p53-responsive genes by genotoxic stress in hematopoietic cells containing wild-type and mutant p53.
Gene expression 1999;8(4):197-206.
1998: B Gong; Q Chen; alex almasan
Ionizing radiation stimulates mitochondrial gene expression and activity.
Radiation research 1998;150(5):505-12.
1998: T G Paulson; alex almasan; Linnea Brody; Geoffrey M Wahl
Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage.
Molecular and cellular biology 1998;18(5):3089-100.
1995: W Li; J Fan; Daniel Hochhauser; Debabrata Banerjee; Z Zielinski; alex almasan; Y Yin; R Kelly; Geoffrey M Wahl; Joseph R Bertino
Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10436-40.
1995: alex almasan; Y Yin; R E Kelly; E Y Lee; A Bradley; W Li; Joseph R Bertino; Geoffrey M Wahl
Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5436-40.
1994: alex almasan; David J Mangelsdorf; Estelita S Ong; Geoffrey M Wahl; Ronald M Evans
Chromosomal localization of the human retinoid X receptors.
Genomics 1994;20(3):397-403.
1991: alex almasan; N C Mishra
Recombination by sequence repeats with formation of suppressive or residual mitochondrial DNA in Neurospora.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7684-8.
1990: alex almasan; N C Mishra
Characterization of a novel plasmid-like element in Neurospora crassa derived mostly from the mitochondrial DNA.
Nucleic acids research 1990;18(19):5871-7.
1990: N C Mishra; alex almasan; M Cooley
Characterization of eukaryotic DNA polymerases: aphidicolin resistant mutants of Neurospora with altered DNA polymerase.
Progress in clinical and biological research 1990;344():295-313.
1988: alex almasan; N C Mishra
Molecular characterization of the mitochondrial DNA of a new stopper mutant ER-3 of Neurospora crassa.
Genetics 1988;120(4):935-45.