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Florian Brueckner

Research Profile

Chemicals & Drugs

Physiology

Transcription, Genetic

Living Beings

Saccharomyces cerevisiae

Concepts & Ideas

Procedures

X Ray Crystallography

Disorders

DNA Damage

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Publications

TOP 3
Jasmin F Sydow; Florian Brueckner; Alan C M Cheung; Gerke E Damsma; Stefan Dengl; Elisabeth Lehmann; Dmitry Vassylyev; Patrick Cramer
Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Florian Brueckner; Julio Ortiz; Patrick Cramer
A movie of the RNA polymerase nucleotide addition cycle.
Florian Brueckner; Karim-Jean Armache; Alan Cheung; Gerke E Damsma; Hubert Kettenberger; Elisabeth Lehmann; Jasmin Sydow; Patrick Cramer
Structure-function studies of the RNA polymerase II elongation complex.

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All Publications

2009: Jasmin F Sydow; Florian Brueckner; Alan C M Cheung; Gerke E Damsma; Stefan Dengl; Elisabeth Lehmann; Dmitry Vassylyev; Patrick Cramer
Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Molecular cell 2009;34(6):710-21.
2009: Florian Brueckner; Julio Ortiz; Patrick Cramer
A movie of the RNA polymerase nucleotide addition cycle.
Current opinion in structural biology 2009;19(3):294-9.
2009: Florian Brueckner; Karim-Jean Armache; Alan Cheung; Gerke E Damsma; Hubert Kettenberger; Elisabeth Lehmann; Jasmin Sydow; Patrick Cramer
Structure-function studies of the RNA polymerase II elongation complex.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 2):112-20.
2008: Florian Brueckner; Patrick Cramer
Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation.
Nature structural & molecular biology 2008;15(8):811-8.
2008: Patrick Cramer; Karim-Jean Armache; Sonja Baumli; S Benkert; Florian Brueckner; C Buchen; G E Damsma; S Dengl; S R Geiger; A J Jasiak; A Jawhari; Stefan Jennebach; T Kamenski; Hubert Kettenberger; C-D Kuhn; E Lehmann; Kristin Leike; J F Sydow; A Vannini
Structure of eukaryotic RNA polymerases.
Annual review of biophysics 2008;37():337-52.
2007: Gerke E Damsma; Aaron Alt; Florian Brueckner; Thomas Carell; Patrick Cramer
Mechanism of transcriptional stalling at cisplatin-damaged DNA.
Nature structural & molecular biology 2007;14(12):1127-33.
2007: Elisabeth Lehmann; Florian Brueckner; Patrick Cramer
Molecular basis of RNA-dependent RNA polymerase II activity.
Nature 2007;450(7168):445-9.
2007: Ekaterina Kashkina; Michael Anikin; Florian Brueckner; Elisabeth Lehmann; Sergey N Kochetkov; William T McAllister; Patrick Cramer; Dmitry Temiakov
Multisubunit RNA polymerases melt only a single DNA base pair downstream of the active site.
The Journal of biological chemistry 2007;282(30):21578-82.
2007: Florian Brueckner; Patrick Cramer
DNA photodamage recognition by RNA polymerase II.
FEBS letters 2007;581(15):2757-60.
2007: Florian Brueckner; Ulrich Hennecke; Thomas Carell; Patrick Cramer
CPD damage recognition by transcribing RNA polymerase II.
Science (New York, N.Y.) 2007;315(5813):859-62.
2006: Ekaterina Kashkina; Michael Anikin; Florian Brueckner; Richard T Pomerantz; William T McAllister; Patrick Cramer; Dmitry Temiakov
Template misalignment in multisubunit RNA polymerases and transcription fidelity.
Molecular cell 2006;24(2):257-66.
2006: Hubert Kettenberger; Alexander Eisenführ; Florian Brueckner; Mirko Theis; Michael Famulok; Patrick Cramer
Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs.
Nature structural & molecular biology 2006;13(1):44-8.