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Basetti Madhu

Research Profile

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Magnetic Resonance Spectroscopy

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Xiaoke Yin; Ignat Drozdov; Joseph Dwyer; Lindsay M Edwards; John Griffiths; Sarah R Langley; Basetti Madhu; Ursula Mayr; Adam Nabeebaccus; Ajay M Shah; Qiuru Xing; Manuel Mayr
Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome.
Dominick J O McIntyre; Shen-Han Lee; Basetti Madhu; John R Griffiths
Magnetic resonance spectroscopy of cancer metabolism and response to therapy.
Tashinga E Bapiro; Natalie Cook; Kristopher K Frese; Mae A Goldgraben; John R Griffiths; Michael A Jacobetz; Basetti Madhu; Kenneth P Olive; Frances M Richards; Donna-Michelle Smith; David A Tuveson; Duncan I Jodrell
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

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All Publications

2013: Xiaoke Yin; Ignat Drozdov; Joseph Dwyer; Lindsay M Edwards; John Griffiths; Sarah R Langley; Basetti Madhu; Ursula Mayr; Adam Nabeebaccus; Ajay M Shah; Qiuru Xing; Manuel Mayr
Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome.
Journal of molecular and cellular cardiology 2013;55():27-30.
2012: Dominick J O McIntyre; Shen-Han Lee; Basetti Madhu; John R Griffiths
Magnetic resonance spectroscopy of cancer metabolism and response to therapy.
Radiation research 2012;177(4):398-435.
2011: Tashinga E Bapiro; Natalie Cook; Kristopher K Frese; Mae A Goldgraben; John R Griffiths; Michael A Jacobetz; Basetti Madhu; Kenneth P Olive; Frances M Richards; Donna-Michelle Smith; David A Tuveson; Duncan I Jodrell
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.
Cancer chemotherapy and pharmacology 2011;68(5):1243-53.
2011: Charles E Massie; Nik Mathews; Boris Adryan; Helene Bon; Joan Boren; Kevin M Brindle; Gina M Denicola; Ladan Fazli; Martin E Gleave; John Griffiths; james hadfield; Andy Lynch; Scott K Lyons; Stewart Macarthur; Basetti Madhu; David E Neal; Michelle Osborne; Antonio Ramos-Montoya; Paul S Rennie; Helen Scott; Naomi Sharma; Donna-Michelle Smith; Rory Stark; Anne Warren; Vinny Zecchini; Ian G Mills
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.
The EMBO journal 2011;30(13):2719-33.
2011: Manuel Mayr; Dalit May; Oren Gordon; Basetti Madhu; Dan Gilon; Xiaoke Yin; Qiuru Xing; Ignat Drozdov; Chrysanthi Ainali; Sophia Tsoka; Qingbo Xu; John Griffiths; Anton Horrevoets; Eli Keshet
Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome.
Journal of molecular and cellular cardiology 2011;50(6):982-90.
2009: Manuel Mayr; David Grainger; Ursula Mayr; Aurelie S Leroyer; Guy Leseche; Anissa Sidibe; Olivier Herbin; Xiaoke Yin; Aldrin Gomes; Basetti Madhu; John R Griffiths; Qingbo Xu; Alain Tedgui; Chantal M Boulanger
Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
Circulation. Cardiovascular genetics 2009;2(4):379-88.
2009: Kenneth P Olive; Michael Jacobetz; Christian J Davidson; Aarthi Gopinathan; Dominick McIntyre; Davina Honess; Basetti Madhu; Mae A Goldgraben; Meredith E Caldwell; David Allard; Kristopher K Frese; Gina Denicola; Christine Feig; Chelsea Combs; Stephen P Winter; Heather Ireland-Zecchini; Stefanie Reichelt; William J Howat; ALEX CHANG; Mousumi Dhara; Lifu Wang; Felix Rückert; Robert Grützmann; Christian Pilarsky; Kamel Izeradjene; Sunil R Hingorani; Pearl Huang; Susan E Davies; William Plunkett; Merrill Egorin; Ralph Hruban; Nigel Whitebread; Karen McGovern; Julian Adams; Christine A Iacobuzio-Donahue; John Griffiths; David A Tuveson
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Science (New York, N.Y.) 2009;324(5933):1457-61.
2009: Manuel Mayr; David Liem; Jun Zhang; Xiaohai Li; Nuraly K Avliyakulov; Jeong In Yang; Glen Young; Tom M Vondriska; Christophe Ladroue; Basetti Madhu; John R Griffiths; Aldrin Gomes; Qingbo Xu; Peipei Ping
Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.
Journal of molecular and cellular cardiology 2009;46(2):268-77.
2008: Basetti Madhu; Simon P Robinson; Franklyn Arron Howe; John R Griffiths
Effect of Gd-DTPA-BMA on choline signals of HT29 tumors detected by in vivo 1H MRS.
Journal of magnetic resonance imaging : JMRI 2008;28(5):1201-8.
2008: Manuel Mayr; Anna Zampetaki; Anissa Sidibe; Ursula Mayr; Xiaoke Yin; Ayesha I De Souza; Yuen-Li Chung; Basetti Madhu; Paul H Quax; Yanhua Hu; John R Griffiths; Qingbo Xu
Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.
Circulation research 2008;102(9):1046-56.
2008: Manuel Mayr; Shamil Yusuf; Graeme Weir; Yuen-Li Chung; Ursula Mayr; Xiaoke Yin; Christophe Ladroue; Basetti Madhu; Neil Roberts; Ayesha De Souza; Salim Fredericks; Marion Stubbs; John R Griffiths; Marjan Jahangiri; Qingbo Xu; A John Camm
Combined metabolomic and proteomic analysis of human atrial fibrillation.
Journal of the American College of Cardiology 2008;51(5):585-94.
2007: Manuel Mayr; Basetti Madhu; Qingbo Xu
Proteomics and metabolomics combined in cardiovascular research.
Trends in cardiovascular medicine 2007;17(2):43-8.
2006: Basetti Madhu; John C Waterton; John R Griffiths; Anderson Ryan; Simon P Robinson
The response of RIF-1 fibrosarcomas to the vascular-disrupting agent ZD6126 assessed by in vivo and ex vivo 1H magnetic resonance spectroscopy.
Neoplasia (New York, N.Y.) 2006;8(7):560-7.
2006: Nada M S Al-Saffar; Helen Troy; Ana Ramírez de Molina; Laura E Jackson; Basetti Madhu; John R Griffiths; Martin Leach; Paul Workman; Juan Carlos Lacal; Ian R Judson; Yuen-Li Chung
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
Cancer research 2006;66(1):427-34.
2005: Lesley D McPhail; Yuen-Li Chung; Basetti Madhu; Simon Clark; John R Griffiths; Lloyd R Kelland; Simon P Robinson
Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3705-13.
2002: Basetti Madhu; I Elmroth; A Lundgren; B Abrahamsson; Bassam Soussi
A novel evaluation of subcutaneous formulations by in vivo magnetic resonance imaging (MRI).
Pharmacological research : the official journal of the Italian Pharmacological Society 2002;45(3):207-12.
2001: Elmir Omerovic; Entela Bollano; Reza Mobini; Basetti Madhu; V Kujacic; Bassam Soussi; Ake Hjalmarson; Finn Waagstein
Selective beta(1)-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling.
Biochemical and biophysical research communications 2001;281(2):491-8.
2001: Daniel J Lukes; Basetti Madhu; Christer Kjellström; Malin Gustavsson; Lars Mjörnstedt; Michael Olausson; Bassam Soussi
Decreasing ratios of phosphocreatine to beta-ATP correlates to progressive acute rejection in a concordant mouse heart to rat xenotransplantation model.
Scandinavian journal of immunology 2001;53(2):171-5.
2000: Elmir Omerovic; Entela Bollano; Reza Mobini; V Kujacic; Basetti Madhu; Bassam Soussi; Michael Fu; Ake Hjalmarson; Finn Waagstein; Jörgen Isgaard
Growth hormone improves bioenergetics and decreases catecholamines in postinfarct rat hearts.
Endocrinology 2000;141(12):4592-9.
2000: Entela Bollano; Elmir Omerovic; Mohammad Bohlooly-Y; V Kujacic; Basetti Madhu; Jan Törnell; Olle G P Isaksson; Bassam Soussi; W Schulze; Michael L X Fu; Göran Matejka; Finn Waagstein; Jörgen Isgaard
Impairment of cardiac function and bioenergetics in adult transgenic mice overexpressing the bovine growth hormone gene.
Endocrinology 2000;141(6):2229-35.
2000: Elmir Omerovic; Basetti Madhu; Entela Bollano; Mohammad Bohlooly-Y; M Bohlooly; Jan Törnell; Jörgen Isgaard; Ake Hjalmarson; Bassam Soussi; Finn Waagstein
In vivo metabolic imaging of cardiac bioenergetics in transgenic mice.
Biochemical and biophysical research communications 2000;271(1):222-8.
1999: Elmir Omerovic; Entela Bollano; Basetti Madhu; V Kujacic; Lisbeth Waagstein; Ake Hjalmarson; Finn Waagstein; Bassam Soussi
Bioenergetic, functional and morphological consequences of postinfarct cardiac remodeling in the rat.
Journal of molecular and cellular cardiology 1999;31(9):1685-95.
1998: Basetti Madhu; J Hjärtstam; Bassam Soussi
Studies of the internal flow process in polymers by 1H NMR microscopy at 500 MHz.
Journal of controlled release : official journal of the Controlled Release Society 1998;56(1-3):95-104.
1997: K Lagerwall; Basetti Madhu; P Daneryd; Tore Scherstén; Bassam Soussi
Purine nucleotides and phospholipids in ischemic and reperfused rat skeletal muscle: effect of ascorbate.
The American journal of physiology 1997;272(1 Pt 2):H83-90.
1996: Basetti Madhu; K Lagerwall; Bassam Soussi
Phosphorus metabolites in different muscles of the rat leg by 31P image-selected in vivo spectroscopy.
NMR in biomedicine 1996;9(8):327-32.