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Tom James

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P Therese Lang; Scott R Brozell; Sudipto Mukherjee; Eric F Pettersen; Elaine C Meng; Veena Thomas; Robert C Rizzo; David A Case; Tom L James; Irwin D Kuntz
DOCK 6: combining techniques to model RNA-small molecule complexes.
Jialing Liu; M Segal; S Yoo; Guo-Yuan Yang; M Kelly; Tom L James; Lawrence Litt
Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress.
Zhihua Du; Sebastian Fenn; Richard Tjhen; Tom L James
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms.

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2009: P Therese Lang; Scott R Brozell; Sudipto Mukherjee; Eric F Pettersen; Elaine C Meng; Veena Thomas; Robert C Rizzo; David A Case; Tom L James; Irwin D Kuntz
DOCK 6: combining techniques to model RNA-small molecule complexes.
RNA (New York, N.Y.) 2009;15(6):1219-30.
2009: Jialing Liu; M Segal; S Yoo; Guo-Yuan Yang; M Kelly; Tom L James; Lawrence Litt
Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress.
Neurochemistry international 2009;54(2):106-10.
2008: Zhihua Du; Sebastian Fenn; Richard Tjhen; Tom L James
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms.
The Journal of biological chemistry 2008;283(42):28757-66.
2008: Zhihua Du; John K Lee; Richard Tjhen; Robert M Stroud; Tom L James
Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2391-6.
2007: Jianying Zeng; Jialing Liu; Guo-Yuan Yang; Mark J S Kelly; Tom L James; Lawrence Litt
Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices.
Anesthesiology 2007;107(4):630-40.
2007: Zhihua Du; John K Lee; Sebastian Fenn; Richard Tjhen; Robert M Stroud; Tom L James
X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2.
RNA (New York, N.Y.) 2007;13(7):1043-51.
2007: Zhihau Du; Sebastian Fenn; Tom L James
Resonance assignment of the first and second KH (hnRNP-K homology) domains of human poly(C)-binding protein-2 (PCBP2).
Journal of biomolecular NMR 2007;38(2):197.
2007: Jianying Zeng; Guo-Yuan Yang; Weihai Ying; Mark Kelly; Kiyoshi Hirai; Tom L James; Raymond Swanson; Lawrence Litt
Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(2):304-15.
2007: Nikolai B Ulyanov; Kinneret Shefer; Tom L James; Yehuda Tzfati
Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates.
Nucleic acids research 2007;35(18):6150-60.
2007: Sebastian Fenn; Zhihua Du; John K Lee; Richard Tjhen; Robert M Stroud; Tom L James
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution.
Nucleic acids research 2007;35(8):2651-60.
2007: Anwer Mujeeb; Nikolai B Ulyanov; Stefanos Georgantis; Ivan Smirnov; Janet Chung; Tristam PARSLOW; Tom L James
Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding.
Nucleic acids research 2007;35(6):2026-34.
2006: Moriz Mayer; P Therese Lang; Sabina Gerber; Peter B Madrid; Irene Gómez Pinto; R Kiplin Guy; Tom L James
Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA.
Chemistry & biology 2006;13(9):993-1000.
2006: Nikolai B Ulyanov; Anwer Mujeeb; Zhihua Du; Marco Tonelli; Tristam PARSLOW; Tom L James
NMR structure of the full-length linear dimer of stem-loop-1 RNA in the HIV-1 dimer initiation site.
The Journal of biological chemistry 2006;281(23):16168-77.
2005: Zhihua Du; John K Lee; Richard Tjhen; Shang Li; Hu Pan; Robert M Stroud; Tom L James
Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A.
The Journal of biological chemistry 2005;280(46):38823-30.
2005: Moriz Mayer; Tom L James
Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target.
Methods in enzymology 2005;394():571-87.
2004: Aviva Lapidot; Veerappan Vijayabaskar; Alexander Litovchick; Jingua Yu; Tom L James
Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy.
FEBS letters 2004;577(3):415-21.
2004: Zhihua Du; Jinghua Yu; Yihong Chen; Raul Andino; Tom L James
Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2.
The Journal of biological chemistry 2004;279(46):48126-34.
2004: Zhihua Du; Jinghua Yu; Nikolai B Ulyanov; Raul Andino; Tom L James
Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses.
Biochemistry 2004;43(38):11959-72.
2004: Jianying Zeng; Kiyoshi Hirai; Guo-Yuan Yang; Weihai Ying; Raymond Swanson; Mark Kelly; Moriz Mayer; Tom L James; Lawrence Litt
Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices.
Journal of bioenergetics and biomembranes 2004;36(4):415-9.
2004: Zhihua Du; Nikolai B Ulyanov; Jinghua Yu; Raul Andino; Tom L James
NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA.
Biochemistry 2004;43(19):5757-71.
2004: Kiyoshi Hirai; Takeshi Hayashi; Pak H Chan; Jianying Zeng; Guo-Yuan Yang; Vladimir J Basus; Tom L James; Lawrence Litt
PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis.
Brain research. Molecular brain research 2004;124(1):51-61.
2004: Kazuo Kuwata; Yuji O Kamatari; Kazuyuki Akasaka; Tom L James
Slow conformational dynamics in the hamster prion protein.
Biochemistry 2004;43(15):4439-46.
2004: Moriz Mayer; Tom L James
NMR-based characterization of phenothiazines as a RNA binding scaffold.
Journal of the American Chemical Society 2004;126(13):4453-60.
2003: Kazuo Kuwata; Tomoharu Matumoto; Hong Cheng; Kuniaki Nagayama; Tom L James; Heinrich Roder
NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14790-5.
2003: Marco Tonelli; Nikolai B Ulyanov; Todd M Billeci; Boleslaw Karwowski; Piotr Guga; Wojciech J Stec; Tom L James
Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition?
Biophysical journal 2003;85(4):2525-38.
2003: Zhihua Du; Jinghua Yu; Raul Andino; Tom L James
Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3.
Biochemistry 2003;42(15):4373-83.
2003: Lawrence Litt; Kiyoshi Hirai; Vladimir J Basus; Tom L James
Temperature control of respiring rat brain slices during high field NMR spectroscopy.
Brain research. Brain research protocols 2003;10(3):191-8.
2003: Kiyoshi Hirai; T Hayashi; Pak H Chan; Vladimir J Basus; Tom L James; Lawrence Litt
Akt phosphorylation and cell survival after hypoxia-induced cytochrome c release in superfused respiring neonatal rat cerebrocortical slices.
Acta neurochirurgica. Supplement 2003;86():227-30.
2003: Lawrence Litt; Kiyoshi Hirai; Vladimir J Basus; Tom L James
NTP and PCr responses to hypoxia by hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical slices: an NMR spectroscopy study at 14.1 Tesla.
Acta neurochirurgica. Supplement 2003;86():71-4.
2002: Luis R Comolli; Ivan Smirnov; Lifeng Xu; Elizabeth H Blackburn; Tom L James
A molecular switch underlies a human telomerase disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16998-7003.
2002: Moriz Mayer; Tom L James
Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O.
Journal of the American Chemical Society 2002;124(45):13376-7.
2002: Luis R Comolli; Nikolai B Ulyanov; Ana Maria Soto; Luis A Marky; Tom L James; William H Gmeiner
NMR structure of the 3' stem-loop from human U4 snRNA.
Nucleic acids research 2002;30(20):4371-9.
2002: Kazuo Kuwata; Hua Li; Hiroaki Yamada; Giuseppe Legname; Stanley B Prusiner; Kazuyuki Akasaka; Tom L James
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?
Biochemistry 2002;41(41):12277-83.
2002: Kiyoshi Hirai; Taku Sugawara; Pak H Chan; Vladimir J Basus; Tom L James; Lawrence Litt
Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices.
Journal of neurochemistry 2002;83(2):309-19.
2002: Jeffrey Macdonald; Olga Schmidlin; Tom L James
In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(3):430-9.
2002: Zhihua Du; Kenneth E Lind; Tom L James
Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening.
Chemistry & biology 2002;9(6):707-12.
2002: Nikolai B Ulyanov; William R Bauer; Tom L James
High-resolution NMR structure of an AT-rich DNA sequence.
Journal of biomolecular NMR 2002;22(3):265-80.
2002: Kenneth E Lind; Zhihua Du; Koh Fujinaga; B Matija Peterlin; Tom L James
Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.
Chemistry & biology 2002;9(2):185-93.
2002: David Konerding; Tom L James; Eric Trump; Ana Maria Soto; Luis A Marky; William H Gmeiner
NMR structure of a gemcitabine-substituted model Okazaki fragment.
Biochemistry 2002;41(3):839-46.
2001: M Tonelli; R J Peters; Tom L James; D A Agard
The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus.
FEBS letters 2001;509(2):161-8.
2001: C Kojima; Nikolai B Ulyanov; M Kainosho; Tom L James
Slow motion in the CAA*TTG sequence of a DNA decamer duplex studied by NMR.
Biochemistry 2001;40(24):7239-46.
2001: M Song; H Shao; Anwer Mujeeb; Tom L James; W L Miller
Molten-globule structure and membrane binding of the N-terminal protease-resistant domain (63-193) of the steroidogenic acute regulatory protein (StAR).
The Biochemical journal 2001;356(Pt 1):151-8.
2001: Tom L James
NMR determination of oligonucleotide structure.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2001;Chapter 7():Unit 7.2.
2000: A V Filikov; V Mohan; Timothy A Vickers; Richard H Griffey; PD Cook; R A Abagyan; Tom L James
Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR.
Journal of computer-aided molecular design 2000;14(6):593-610.
2000: A Görler; Nikolai B Ulyanov; Tom L James
Determination of the populations and structures of multiple conformers in an ensemble from NMR data: multiple-copy refinement of nucleic acid structures using floating weights.
Journal of biomolecular NMR 2000;16(2):147-64.
2000: Natalie J Serkova; Lawrence Litt; Dieter Leibfritz; Bernard Hausen; R E Morris; Tom L James; Leslie Z Benet; Uwe Christians
The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates.
British journal of pharmacology 2000;129(3):485-92.
1999: U Schmitz; S Behrens; Douglas Freymann; RJ Keenan; P Lukavsky; Peter Walter; Tom L James
Structure of the phylogenetically most conserved domain of SRP RNA.
RNA (New York, N.Y.) 1999;5(11):1419-29.
1999: Anwer Mujeeb; Tristam PARSLOW; A Zarrinpar; C Das; Tom L James
NMR structure of the mature dimer initiation complex of HIV-1 genomic RNA.
FEBS letters 1999;458(3):387-92.
1999: U Schmitz; Tom L James; P Lukavsky; Peter Walter
Structure of the most conserved internal loop in SRP RNA.
Nature structural biology 1999;6(7):634-8.
1999: Lawrence Litt; MT Espanol; K Hasegawa; LH Chang; George A Gregory; Tom L James; M Flint Beal; Pak H Chan
NOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices.
Anesthesiology 1999;90(5):1392-401.
1999: Natalie J Serkova; Lawrence Litt; Tom L James; Wolfgang Sadée; Dieter Leibfritz; Leslie Z Benet; Uwe Christians
Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy.
The Journal of pharmacology and experimental therapeutics 1999;289(2):800-6.
1999: H Liu; Shauna Farr-Jones; Nikolai B Ulyanov; M Llinas; Susan Marqusee; Darlene Groth; Fred Cohen; Stanley B Prusiner; Tom L James
Solution structure of Syrian hamster prion protein rPrP(90-231).
Biochemistry 1999;38(17):5362-77.
1999: David Konerding; Thomas E Cheatham; Peter A Kollman; Tom L James
Restrained molecular dynamics of solvated duplex DNA using the particle mesh Ewald method.
Journal of biomolecular NMR 1999;13(2):119-31.
1999: C Kojima; A Ono; M Kainosho; Tom L James
Quantitative measurement of transverse and longitudinal cross-correlation between 13C-1H dipolar interaction and 13C chemical shift anisotropy: application to a 13C-labeled DNA duplex.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1999;136(2):169-75.
1999: P Furrer; Todd M Billeci; A Donati; C Kojima; Boleslaw Karwowski; A Sierzchala; Wojciech J Stec; Tom L James
Structural effect of complete [Rp]-phosphorothioate and phosphorodithioate substitutions in the DNA strand of a model antisense inhibitor-target RNA complex.
Journal of molecular biology 1999;285(4):1609-22.
1999: William H Gmeiner; David Konerding; Tom L James
Effect of cytarabine on the NMR structure of a model okazaki fragment from the SV40 genome.
Biochemistry 1999;38(4):1166-75.
1998: C Kojima; A Ono; M Kainosho; Tom L James
DNA duplex dynamics: NMR relaxation studies of a decamer with uniformly 13C-labeled purine nucleotides.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;135(2):310-33.
1998: U Schmitz; A Donati; Tom L James; Nikolai B Ulyanov; L Yao
Small structural ensembles for a 17-nucleotide mimic of the tRNA T psi C-loop via fitting dipolar relaxation rates with the quadratic programming algorithm.
Biopolymers 1998;46(5):329-42.
1998: Nikolai B Ulyanov; VI Ivanov; EE Minyat; E B Khomyakova; M V Petrova; K Lesiak; Tom L James
A pseudosquare knot structure of DNA in solution.
Biochemistry 1998;37(37):12715-26.
1998: M Tonelli; E Ragg; A M Bianucci; K Lesiak; Tom L James
Nuclear magnetic resonance structure of d(GCATATGATAG). d(CTATCATATGC): a consensus sequence for promoters recognized by sigma K RNA polymerase.
Biochemistry 1998;37(34):11745-61.
1998: M Tonelli; Tom L James
Insights into the dynamic nature of DNA duplex structure via analysis of nuclear Overhauser effect intensities.
Biochemistry 1998;37(33):11478-87.
1998: Michael A Baldwin; Tom L James; Fred Cohen; Stanley B Prusiner
The three-dimensional structure of prion protein: implications for prion disease.
Biochemical Society transactions 1998;26(3):481-6.
1998: Anwer Mujeeb; Jared L Clever; Todd M Billeci; Tom L James; Tristam PARSLOW
Structure of the dimer initiation complex of HIV-1 genomic RNA.
Nature structural biology 1998;5(6):432-6.
1998: A V Filikov; Tom L James
Structure-based design of ligands for protein basic domains: application to the HIV-1 Tat protein.
Journal of computer-aided molecular design 1998;12(3):229-40.
1998: Jeffrey Macdonald; M Grillo; Olga Schmidlin; D T Tajiri; Tom L James
NMR spectroscopy and MRI investigation of a potential bioartificial liver.
NMR in biomedicine 1998;11(2):55-66.
1998: MT Espanol; Lawrence Litt; K Hasegawa; LH Chang; Jeffrey Macdonald; George A Gregory; Tom L James; Pak H Chan
Fructose-1,6-bisphosphate preserves adenosine triphosphate but not intracellular pH during hypoxia in respiring neonatal rat brain slices.
Anesthesiology 1998;88(2):461-72.
1997: DG Donne; JH Viles; Darlene Groth; IR Mehlhorn; Tom L James; Fred Cohen; Stanley B Prusiner; Peter Wright; H Jane Dyson
Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13452-7.
1997: David Peretz; R Anthony Williamson; Yoichi Matsunaga; Hana Serban; Clemencia Pinilla; RB Bastidas; R Rozenshteyn; Tom L James; R A Houghten; Fred Cohen; Stanley B Prusiner; Dennis R Burton
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.
Journal of molecular biology 1997;273(3):614-22.
1997: Tom L James; H Liu; Nikolai B Ulyanov; Shauna Farr-Jones; Hui Zhang; DG Donne; Kiyotoshi Kaneko; Darlene Groth; IR Mehlhorn; Stanley B Prusiner; Fred Cohen
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10086-91.
1997: Kiyotoshi Kaneko; L Zulianello; M Scott; C M Cooper; Andrew C Wallace; Tom L James; Fred Cohen; Stanley B Prusiner
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10069-74.
1997: K Kuwata; H Liu; T Schleich; Tom L James
Rotational correlation times of internuclear vectors in a DNA duplex with G-A mismatch determined in aqueous solution by complete relaxation matrix analysis of off-resonance ROESY (O-ROESY) spectra.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;128(1):70-81.
1997: M D Sorensen; S Bjorn; K Norris; O Olsen; L Petersen; Tom L James; Jens Led
Solution structure and backbone dynamics of the human alpha3-chain type VI collagen C-terminal Kunitz domain,.
Biochemistry 1997;36(34):10439-50.
1997: L J Yao; Tom L James; James T Kealey; Daniel V Santi; U Schmitz
The dynamic NMR structure of the T psi C-loop: implications for the specificity of tRNA methylation.
Journal of biomolecular NMR 1997;9(3):229-44.
1997: Hui Zhang; J Stockel; IR Mehlhorn; Darlene Groth; Michael A Baldwin; Stanley B Prusiner; Tom L James; Fred Cohen
Physical studies of conformational plasticity in a recombinant prion protein.
Biochemistry 1997;36(12):3543-53.
1997: Anwer Mujeeb; M A Reynolds; Tom L James
High-resolution NMR of an antisense DNA x RNA hybrid containing alternating chirally pure Rp methylphosphonates in the DNA backbone.
Biochemistry 1997;36(9):2371-9.
1996: U Schmitz; Douglas Freymann; Tom L James; RJ Keenan; R Vinayak; Peter Walter
NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP).
RNA (New York, N.Y.) 1996;2(12):1213-27.
1996: H Liu; M Tonelli; Tom L James
Correcting NOESY cross-peak intensities for partial relaxation effects enabling accurate distance information.
Journal of magnetic resonance. Series B 1996;111(1):85-9.
1996: Anwer Mujeeb; Tristam PARSLOW; Y C Yuan; Tom L James
Aqueous solution structure of a hybrid lentiviral Tat peptide and a model of its interaction with HIV-1 TAR RNA.
Journal of biomolecular structure & dynamics 1996;13(4):649-60.
1996: MT Espanol; Lawrence Litt; L H Chang; Tom L James; Philip R Weinstein; Pak H Chan
Adult rat brain-slice preparation for nuclear magnetic resonance spectroscopy studies of hypoxia.
Anesthesiology 1996;84(1):201-10.
1995: H Liu; H P Spielmann; Nikolai B Ulyanov; David E Wemmer; Tom L James
Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors.
Journal of biomolecular NMR 1995;6(4):390-402.
1995: Hui Zhang; Kiyotoshi Kaneko; J T Nguyen; T L Livshits; Michael A Baldwin; Fred Cohen; Tom L James; Stanley B Prusiner
Conformational transitions in peptides containing two putative alpha-helices of the prion protein.
Journal of molecular biology 1995;250(4):514-26.
1995: C González; Wojciech J Stec; M A Reynolds; Tom L James
Structure and dynamics of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety: NMR and molecular dynamics with conventional and time-averaged restraints.
Biochemistry 1995;34(15):4969-82.
1995: H Liu; D L Banville; V J Basus; Tom L James
Deriving accurate interproton distances from ROESY spectra with limited knowledge of scalar coupling constants via the CARNIVAL algorithm. An iterative complete-relaxation-matrix approach.
Journal of magnetic resonance. Series B 1995;107(1):51-9.
1995: Nikolai B Ulyanov; Tom L James
Statistical analysis of DNA duplex structural features.
Methods in enzymology 1995;261():90-120.
1995: U Schmitz; Tom L James
How to generate accurate solution structures of double-helical nucleic acid fragments using nuclear magnetic resonance and restrained molecular dynamics.
Methods in enzymology 1995;261():3-44.
1995: Nikolai B Ulyanov; U Schmitz; A Kumar; Tom L James
Probability assessment of conformational ensembles: sugar repuckering in a DNA duplex in solution.
Biophysical journal 1995;68(1):13-24.
1994: Nikolai B Ulyanov; K D Bishop; VI Ivanov; Tom L James
Tertiary base pair interactions in slipped loop-DNA: an NMR and model building study.
Nucleic acids research 1994;22(20):4242-9.
1994: C González; Wojciech J Stec; A Kobylanska; R I Hogrefe; M Reynolds; Tom L James
Structural study of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety by NMR: extraction of distance and torsion angle constraints and imino proton exchange rates.
Biochemistry 1994;33(37):11062-72.
1994: Anwer Mujeeb; K Bishop; B Matija Peterlin; Christoph W Turck; Tristam PARSLOW; Tom L James
NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8248-52.
1994: MT Espanol; Lawrence Litt; Y Xu; L H Chang; Tom L James; Philip R Weinstein; Pak H Chan
19F NMR calcium changes, edema and histology in neonatal rat brain slices during glutamate toxicity.
Brain research 1994;647(1):172-6.
1994: MT Espanol; Y Xu; Lawrence Litt; G Y Yang; L H Chang; Tom L James; P Weinstein; Pak H Chan
Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(2):269-78.
1994: John Kurhanewicz; Devron H Char; Paul R Stauffer; Jeanne M Quivey; Tom L James
31P magnetic resonance spectroscopy after combined hyperthermia and radiation.
Current eye research 1994;13(2):151-6.
1994: K D Bishop; F J Blocker; W Egan; Tom L James
Hepatitis B virus direct repeat sequence: imino proton exchange rates and distance and torsion angle restraints from NMR.
Biochemistry 1994;33(2):427-38.
1994: K Weisz; Richard H Shafer; W Egan; Tom L James
Solution structure of the octamer motif in immunoglobulin genes via restrained molecular dynamics calculations.
Biochemistry 1994;33(1):354-66.
1994: MT Espanol; Y Xu; Lawrence Litt; L H Chang; Tom L James; Philip R Weinstein; Pak H Chan
Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate.
Acta neurochirurgica. Supplementum 1994;60():58-61.
1994: Tom L James
Assessment of quality of derived macromolecular structures.
Methods in enzymology 1994;239():416-39.
1994: S Imaizumi; L Chang; Y Cohen; Pak H Chan; Philip R Weinstein; T Yoshimoto; Tom L James
Reduction of superoxide dismutase activity correlates with visualization of edema by T2-weighted MR imaging in focal ischemic rat brain.
Neurologia medico-chirurgica 1994;34(1):1-9.
1993: Anwer Mujeeb; S M Kerwin; G L Kenyon; Tom L James
Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra.
Biochemistry 1993;32(49):13419-31.
1993: U Schmitz; Nikolai B Ulyanov; A Kumar; Tom L James
Molecular dynamics with weighted time-averaged restraints for a DNA octamer. Dynamic interpretation of nuclear magnetic resonance data.
Journal of molecular biology 1993;234(2):373-89.
1993: Nikolai B Ulyanov; U Schmitz; Tom L James
Metropolis Monte Carlo calculations of DNA structure using internal coordinates and NMR distance restraints: an alternative method for generating a high-resolution solution structure.
Journal of biomolecular NMR 1993;3(5):547-68.
1993: Lawrence Litt; Y Xu; Y Cohen; Tom L James
Nonmagnetic hyperbaric chamber for in vivo NMR spectroscopy studies of small animals.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;29(6):812-6.
1993: H Shimizu; Steven H Graham; L H Chang; J Mintorovitch; Tom L James; Alan Faden; Philip R Weinstein
Relationship between extracellular neurotransmitter amino acids and energy metabolism during cerebral ischemia in rats monitored by microdialysis and in vivo magnetic resonance spectroscopy.
Brain research 1993;605(1):33-42.
1993: Peter N Bretan; Daniel B Vigneron; Hedvig Hricak; David C Price; T S Benedict Yen; J A Luo; Emil A Tanagho; Tom L James
Assessment of in situ renal transplant viability by 31P-MRS: experimental study in canines.
The American surgeon 1993;59(3):182-7.
1993: Jeffrey Macdonald; John Kurhanewicz; Rajvir Dahiya; MT Espanol; L H Chang; B Goldberg; Tom L James; P Narayan
Effect of glucose and confluency on phosphorus metabolites of perfused human prostatic adenocarcinoma cells as determined by 31P MRS.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;29(2):244-8.
1993: John Kurhanewicz; Rajvir Dahiya; Jeffrey Macdonald; L H Chang; Tom L James; P Narayan
Citrate alterations in primary and metastatic human prostatic adenocarcinomas: 1H magnetic resonance spectroscopy and biochemical study.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;29(2):149-57.
1992: P A Mills; A Rashid; Tom L James
Monte Carlo calculations of ion distributions surrounding the oligonucleotide d(ATATATATAT)2 in the B, A, and wrinkled D conformations.
Biopolymers 1992;32(11):1491-501.
1992: MT Espanol; Lawrence Litt; G Y Yang; L H Chang; Pak H Chan; Tom L James; Philip R Weinstein
Tolerance of low intracellular pH during hypercapnia by rat cortical brain slices: A 31P/1H NMR study.
Journal of neurochemistry 1992;59(5):1820-8.
1992: L H Chang; H Shimizu; H Abiko; Raymond Swanson; Alan Faden; Tom L James; Philip R Weinstein
Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(6):1030-8.
1992: Anwer Mujeeb; S M Kerwin; W Egan; G L Kenyon; Tom L James
A potential gene target in HIV-1: rationale, selection of a conserved sequence, and determination of NMR distance and torsion angle constraints.
Biochemistry 1992;31(39):9325-38.
1992: U Schmitz; I Sethson; W M Egan; Tom L James
Solution structure of a DNA octamer containing the Pribnow box via restrained molecular dynamics simulation with distance and torsion angle constraints derived from two-dimensional nuclear magnetic resonance spectral fitting.
Journal of molecular biology 1992;227(2):510-31.
1992: K Weisz; Richard H Shafer; W Egan; Tom L James
The octamer motif in immunoglobulin genes: extraction of structural constraints from two-dimensional NMR studies.
Biochemistry 1992;31(33):7477-87.
1992: R Stolarski; W Egan; Tom L James
Solution structure of the EcoRI DNA octamer containing 5-fluorouracil via restrained molecular dynamics using distance and torsion angle constraints extracted from NMR spectral simulations.
Biochemistry 1992;31(31):7027-42.
1992: John Kurhanewicz; Rajvir Dahiya; Jeffrey Macdonald; P Jajodia; L H Chang; Tom L James; P Narayan
Phosphorus metabolite characterization of human prostatic adenocarcinoma in a nude mouse model by 31P magnetic resonance spectroscopy and high pressure liquid chromatography.
NMR in biomedicine 1992;5(4):185-92.
1992: Michael F Wendland; S B Iyer; Karen K Fu; K N Lam; Tom L James
Correlations between in vivo 31P MRS measurements, tumor size, cell survival, and hypoxic fraction in the murine EMT6 tumor.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;25(2):217-32.
1992: Hans Widmer; H Abiko; Alan Faden; Tom L James; Philip R Weinstein
Effects of hyperglycemia on the time course of changes in energy metabolism and pH during global cerebral ischemia and reperfusion in rats: correlation of 1H and 31P NMR spectroscopy with fatty acid and excitatory amino acid levels.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(3):456-68.
1992: S H Hu; K Weisz; Tom L James; Richard H Shafer
H-NMR studies on d(GCTTAAGC)2 and its complex with berenil.
European journal of biochemistry / FEBS 1992;204(1):31-8.
1991: John Kurhanewicz; A Thomas; P Jajodia; Michael Weiner; Tom L James; Daniel B Vigneron; P Narayan
31P spectroscopy of the human prostate gland in vivo using a transrectal probe.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;22(2):404-13.
1991: Y Xu; Y Cohen; Lawrence Litt; L H Chang; Tom L James
Tolerance of low cerebral intracellular pH in rats during hyperbaric hypercapnia.
Stroke; a journal of cerebral circulation 1991;22(10):1303-8.
1991: U Schmitz; D A Pearlman; Tom L James
Solution structure of [d(GTATATAC)]2 via restrained molecular dynamics simulations with nuclear magnetic resonance constraints derived from relaxation matrix analysis of two-dimensional nuclear Overhauser effect experiments.
Journal of molecular biology 1991;221(1):271-92.
1991: S Winguth; John Kurhanewicz; M L Wang; Jeanne M Quivey; Tom L James; Devron H Char
31P magnetic resonance spectroscopy (MRS) of experimental orbital myositis.
Investigative ophthalmology & visual science 1991;32(8):2417-22.
1991: P Narayan; P Jajodia; John Kurhanewicz; A Thomas; Jeffrey Macdonald; B Hubesch; M Hedgcock; C M Anderson; Tom L James; Emil A Tanagho
Characterization of prostate cancer, benign prostatic hyperplasia and normal prostates using transrectal 31phosphorus magnetic resonance spectroscopy: a preliminary report.
The Journal of urology 1991;146(1):66-74.
1991: D J Kerwood; G Zon; Tom L James
Structure determination of [d(ATATATAUAT)]2 via two-dimensional NOE spectroscopy and molecular dynamics calculations.
European journal of biochemistry / FEBS 1991;197(3):583-95.
1991: P D Thomas; V J Basus; Tom L James
Protein solution structure determination using distances from two-dimensional nuclear Overhauser effect experiments: effect of approximations on the accuracy of derived structures.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1237-41.
1991: Y Cohen; T Sanada; Lawrence H Pitts; L H Chang; M C Nishimura; Philip R Weinstein; Lawrence Litt; Tom L James
Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;17(1):225-36.
1991: L H Chang; Y Cohen; Philip R Weinstein; L Chileuitt; Tom L James
Interleaved 1H and 31P spectroscopic imaging for studying regional brain injury.
Magnetic resonance imaging 1991;9(2):223-7.
1991: Tom L James; V J Basus
Generation of high-resolution protein structures in solution from multidimensional NMR.
Annual review of physical chemistry 1991;42():501-42.
1990: M Gochin; Tom L James
Solution structure studies of d(AC)4.d(GT)4 via restrained molecular dynamics simulations with NMR constraints derived from two-dimensional NOE and double-quantum-filtered COSY experiments.
Biochemistry 1990;29(51):11172-80.
1990: M Gochin; G Zon; Tom L James
Two-dimensional COSY and two-dimensional NOE spectroscopy of d(AC)4.d(GT)4: extraction of structural constraints.
Biochemistry 1990;29(51):11161-71.
1990: Alan Faden; R Shirane; L H Chang; Tom L James; M Lemke; Philip R Weinstein
Opiate-receptor antagonist improves metabolic recovery and limits neurochemical alterations associated with reperfusion after global brain ischemia in rats.
The Journal of pharmacology and experimental therapeutics 1990;255(2):451-8.
1990: S H Lockhart; Y Cohen; N Yasuda; F Kim; Lawrence Litt; Edmond I Eger; L H Chang; Tom L James
Absence of abundant binding sites for anesthetics in rabbit brain: an in vivo NMR study.
Anesthesiology 1990;73(3):455-60.
1990: Karen K Fu; Michael F Wendland; S B Iyer; K N Lam; H Engeseth; Tom L James
Correlations between in vivo 31P NMR spectroscopy measurements, tumor size, hypoxic fraction and cell survival after radiotherapy.
International journal of radiation oncology, biology, physics 1990;18(6):1341-50.
1990: U Schmitz; G Zon; Tom L James
Deoxyribose conformation in [d(GTATATAC)]2: evaluation of sugar pucker by simulation of double-quantum-filtered COSY cross-peaks.
Biochemistry 1990;29(9):2357-68.
1990: Y Cohen; L H Chang; Lawrence Litt; F Kim; John W Severinghaus; Philip R Weinstein; RL Davis; I Germano; Tom L James
Stability of brain intracellular lactate and 31P-metabolite levels at reduced intracellular pH during prolonged hypercapnia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(2):277-84.
1990: L H Chang; R Shirane; Philip R Weinstein; Tom L James
Cerebral metabolite dynamics during temporary complete ischemia in rats monitored by time-shared 1H and 31P NMR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1990;13(1):6-13.
1990: Tom L James; B A Borgias; A M Bianucci; N Zhou
Determination of DNA and protein structures in solution via complete relaxation matrix analysis of 2D NOE spectra.
Basic life sciences 1990;56():135-54.
1989: A Aria Tzika; Daniel B Vigneron; Hedvig Hricak; M E Moseley; Tom L James; BA Kogan
P-31 MR spectroscopy in assessing testicular torsion: rat model.
Radiology 1989;172(3):753-7.
1989: Daniel B Vigneron; Hedvig Hricak; Tom L James; P B Jajodia; L Nunes; P Narayan
Androgen sensitivity of rat prostate carcinoma studied by 31P NMR spectroscopy, 1H MR imaging, and 23Na MR imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1989;11(2):152-60.
1989: P Narayan; Daniel B Vigneron; P Jajodia; C M Anderson; M W Hedgcock; Emil A Tanagho; Tom L James
Transrectal probe for 1H MRI and 31P MR spectroscopy of the prostate gland.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1989;11(2):209-20.
1989: N Zhou; Tom L James; Richard H Shafer
Binding of actinomycin D to [d(ATCGAT)]2: NMR evidence of multiple complexes.
Biochemistry 1989;28(12):5231-9.
1989: T Watters; J Wikman-Coffelt; S Wu; Tom L James; Richard E Sievers; William W Parmley
Effects of perfusion pressure on energy and work of isolated rat hearts.
Hypertension 1989;13(5):480-8.
1989: Peter N Bretan; Daniel B Vigneron; R D McClure; Hedvig Hricak; R A Tom; M Moseley; Emil A Tanagho; Tom L James
Assessment of male infertility: correlation between results of semen analysis and phosphorus-31 magnetic resonance spectroscopy.
Urology 1989;33(2):116-9.
1989: B A Borgias; Tom L James
Two-dimensional nuclear Overhauser effect: complete relaxation matrix analysis.
Methods in enzymology 1989;176():169-83.
1988: A Delbarre; Stephen Brown; Tom L James; R H Shafer
Spectrophotometric and NMR analysis of the interaction of fluorinated mono- and bifunctional intercalators with DNA, poly(dA-dT), and poly(dG-dC).
Biopolymers 1988;27(12):1953-75.
1988: Daniel B Vigneron; A Aria Tzika; Hedvig Hricak; David C Price; Peter N Bretan; SR Aboseif; S Müller; Tom L James
Complete and partial ureteral obstruction: evaluation of renal effects with P-31 MR spectroscopy and Tc-DMSA scintigraphy.
Radiology 1988;168(3):645-50.
1988: N Zhou; S Manogaran; G Zon; Tom L James
Deoxyribose ring conformation of [d(GGTATACC)]2: an analysis of vicinal proton-proton coupling constants from two-dimensional proton nuclear magnetic resonance.
Biochemistry 1988;27(16):6013-20.
1988: J Wikman-Coffelt; S T Wu; T Watters; Tom L James; William W Parmley; D T Mason
Biochemical regulation of developed intraventricular systolic pressure.
American heart journal 1988;115(4):876-91.
1988: SA Camacho; J Wikman-Coffelt; S T Wu; T A Watters; Elias H Botvinick; Richard E Sievers; Tom L James; G Jasmin; William W Parmley
Improvement in myocardial performance without a decrease in high-energy phosphate metabolites after isoproterenol in Syrian cardiomyopathic hamsters.
Circulation 1988;77(3):712-9.
1988: SA Camacho; William W Parmley; Tom L James; H Abe; S T Wu; Elias H Botvinick; T A Watters; Nelson B Schiller; Richard E Sievers; J Wikman-Coffelt
Substrate regulation of the nucleotide pool during regional ischaemia and reperfusion in an isolated rat heart preparation: a phosphorus-31 magnetic resonance spectroscopy analysis.
Cardiovascular research 1988;22(3):193-203.
1988: N Ishige; Lawrence H Pitts; I Berry; M C Nishimura; Tom L James
The effects of hypovolemic hypotension on high-energy phosphate metabolism of traumatized brain in rats.
Journal of neurosurgery 1988;68(1):129-36.
1988: W Markiewicz; S S Wu; Richard E Sievers; William W Parmley; T A Watters; Tom L James; C B Higgins; J Wikman-Coffelt
Beneficial effects of verapamil during metabolic acidosis in isolated perfused rat hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;1(5):493-502.
1987: N Zhou; A M Bianucci; N Pattabiraman; Tom L James
Solution structure of [d(GGTATACC)]2: wrinkled D structure of the TATA moiety.
Biochemistry 1987;26(24):7905-13.
1987: Daniel Sessler; P Mills; G Gregory; Lawrence Litt; Tom L James
Effects of bicarbonate on arterial and brain intracellular pH in neonatal rabbits recovering from hypoxic lactic acidosis.
The Journal of pediatrics 1987;111(6 Pt 1):817-23.
1987: T A Watters; M F Wendland; William W Parmley; Tom L James; Elias H Botvinick; S T Wu; Richard E Sievers; J Wikman-Coffelt
Factors influencing myocardial response to metabolic acidosis in isolated rat hearts.
The American journal of physiology 1987;253(5 Pt 2):H1261-70.
1987: T L Richards; Max A Keniry; Philip R Weinstein; B M Pereira; B T Andrews; E J Murphy; Tom L James
Measurement of lactate accumulation by in vivo proton NMR spectroscopy during global cerebral ischemia in rats.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;5(4):353-7.
1987: P Mills; Daniel Sessler; M Moseley; W Chew; B Pereira; Tom L James; Lawrence Litt
An in vivo 19F nuclear magnetic resonance study of isoflurane elimination from the rabbit brain.
Anesthesiology 1987;67(2):169-73.
1987: Lawrence Litt; R González-Méndez; Tom L James; Daniel Sessler; P Mills; W Chew; M Moseley; B Pereira; J W Severinghaus; W K Hamilton
An in vivo study of halothane uptake and elimination in the rat brain with fluorine nuclear magnetic resonance spectroscopy.
Anesthesiology 1987;67(2):161-8.
1987: W Markiewicz; S Wu; Richard E Sievers; William W Parmley; Charles B Higgins; Tom L James; G Jasmin; J Wikman-Coffelt
Influence of heart rate on metabolic and hemodynamic parameters in the Syrian hamster cardiomyopathy.
American heart journal 1987;114(2):362-8.
1987: N Ishige; Lawrence H Pitts; L Pogliani; T Hashimoto; M C Nishimura; H M Bartkowski; Tom L James
Effect of hypoxia on traumatic brain injury in rats: Part 2. Changes in high energy phosphate metabolism.
Neurosurgery 1987;20(6):854-8.
1987: L H Chang; B M Pereira; Philip R Weinstein; Max A Keniry; J Murphy-Boesch; Lawrence Litt; Tom L James
Comparison of lactate concentration determinations in ischemic and hypoxic rat brains by in vivo and in vitro 1H NMR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;4(6):575-81.
1987: Peter N Bretan; Daniel B Vigneron; Hedvig Hricak; R D McClure; T S Yen; M Moseley; Emil A Tanagho; Tom L James
Assessment of testicular metabolic integrity with P-31 MR spectroscopy.
Radiology 1987;162(3):867-71.
1987: C Benz; C Hollander; Max A Keniry; Tom L James; M Mitchell
Lactic dehydrogenase isozymes, 31P magnetic resonance spectroscopy, and in vitro antimitochondrial tumor toxicity with gossypol and rhodamine-123.
The Journal of clinical investigation 1987;79(2):517-23.
1987: D A Kass; D L Banville; C A Gooding; Tom L James
31P magnetic resonance spectroscopy of mesenteric ischemia.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;4(1):83-7.
1987: W M Chew; M E Moseley; P A Mills; Daniel Sessler; R González-Méndez; Tom L James; Lawrence Litt
Spin-echo fluorine magnetic resonance imaging at 2 T: in vivo spatial distribution of halothane in the rabbit head.
Magnetic resonance imaging 1987;5(1):51-6.
1987: Peter N Bretan; Daniel B Vigneron; Hedvig Hricak; G M Collins; David C Price; Emil A Tanagho; Tom L James
Assessment of clinical renal preservation by phosphorus-31 magnetic resonance spectroscopy.
The Journal of urology 1987;137(1):146-50.
1987: Tom L James; L H Chang; W Chew; R Gonzalez-Mendez; Lawrence Litt; P Mills; M Moseley; B Pereira; Daniel Sessler; Philip R Weinstein
In situ brain metabolism.
Annals of the New York Academy of Sciences 1987;508():64-80.
1986: E Berman; H Lis; Tom L James
Binding of [1-13C]galactose-enriched hen ovalbumin to Erythrina cristagalli agglutinin as studied by 13C-NMR spectroscopy.
European journal of biochemistry / FEBS 1986;161(3):589-94.
1986: W Markiewicz; S S Wu; William W Parmley; Charles B Higgins; Richard E Sievers; Tom L James; J Wikman-Coffelt; G Jasmin
Evaluation of the hereditary Syrian hamster cardiomyopathy by 31P nuclear magnetic resonance spectroscopy: improvement after acute verapamil therapy.
Circulation research 1986;59(6):597-604.
1986: Peter N Bretan; Daniel B Vigneron; Hedvig Hricak; K P Juenemann; R D Williams; Emil A Tanagho; Tom L James
Assessment of renal preservation by phosphorus-31 magnetic resonance spectroscopy: in vivo normothermic blood perfusion.
The Journal of urology 1986;136(6):1356-9.
1986: A R Margulis; Tom L James
Localized tissue MR spectroscopy.
AJR. American journal of roentgenology 1986;147(6):1327-8.
1986: L A LaPlanche; Tom L James; C Powell; David W. Wilson; B Uznanski; Wojciech J Stec; Michael F Summers; G Zon
Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates.
Nucleic acids research 1986;14(22):9081-93.
1986: E Suzuki; N Pattabiraman; G Zon; Tom L James
Solution structure of [d(A-T)5]2 via complete relaxation matrix analysis of two-dimensional nuclear Overhauser effect spectra and molecular mechanics calculations: evidence for a hydration tunnel.
Biochemistry 1986;25(22):6854-65.
1986: Lawrence Litt; R González-Méndez; Philip R Weinstein; J W Severinghaus; W K Hamilton; J Shuleshko; J Murphy-Boesch; Tom L James
An in vivo 31P NMR study of cerebral hypoxic hypoxia in rats.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1986;3(4):619-25.
1986: Lawrence Litt; R González-Méndez; J W Severinghaus; W K Hamilton; Ira J Rampil; J Shuleshko; J Murphy-Boesch; Tom L James
Cerebral intracellular ADP concentrations during hypercarbia: an in vivo 31P nuclear magnetic resonance study in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1986;6(3):389-92.
1986: Peter N Bretan; Daniel B Vigneron; Tom L James; R D Williams; Hedvig Hricak; K P Juenemann; T S Benedict Yen; Emil A Tanagho
Assessment of renal viability by phosphorus-31 magnetic resonance spectroscopy.
The Journal of urology 1986;135(4):866-71.
1986: Max A Keniry; C Benz; R H Shafer; Tom L James
Noninvasive spectroscopic analysis of fluoropyrimidine metabolism in cultured tumor cells.
Cancer research 1986;46(4 Pt 1):1754-8.
1986: H C Schmidt; C A Gooding; Tom L James
In vivo 31P-MR spectroscopy of the liver in the infant rabbit to study the effect of hypoxia on the phosphorus metabolites and intracellular pH.
Investigative radiology 1986;21(2):156-61.
1986: Alan Koretsky; S Wang; M P Klein; Tom L James; Michael Weiner
31P NMR saturation transfer measurements of phosphorus exchange reactions in rat heart and kidney in situ.
Biochemistry 1986;25(1):77-84.
1986: H C Schmidt; C A Gooding; Tom L James; R Gonzalez-Mendez; J L James
Comparison of in vivo 31P-MR spectra of the brain, liver, and kidney of adult and infant animals.
Pediatric radiology 1986;16(2):144-9.
1985: Lawrence Litt; R González-Méndez; J W Severinghaus; W K Hamilton; J Shuleshko; J Murphy-Boesch; Tom L James
Cerebral intracellular changes during supercarbia: an in vivo 31P nuclear magnetic resonance study in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1985;5(4):537-44.
1985: R González-Méndez; A McNeill; George A Gregory; S D Wall; C A Gooding; Lawrence Litt; Tom L James
Effects of hypoxic hypoxia on cerebral phosphate metabolites and pH in the anesthetized infant rabbit.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1985;5(4):512-6.
1985: Alan Koretsky; V J Basus; Tom L James; M P Klein; Michael Weiner
Detection of exchange reactions involving small metabolite pools using NMR magnetization transfer techniques: relevance to subcellular compartmentation of creatine kinase.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1985;2(6):586-94.
1985: W M Chew; M E Moseley; M C Nishimura; T Hashimoto; Lawrence H Pitts; Tom L James
A novel double-surface coil approach to phosphorus-31 spectroscopy: a study of hemispheric brain injury in the rat.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1985;2(6):567-75.
1985: E Berman; Stephen Brown; Tom L James; R H Shafer
NMR studies of chromomycin A3 interaction with DNA.
Biochemistry 1985;24(24):6887-93.
1985: N Jamin; Tom L James; G Zon
Two-dimensional nuclear Overhauser enhancement investigation of the solution structure and dynamics of the DNA octamer [d(GGTATACC)]2.
European journal of biochemistry / FEBS 1985;152(1):157-66.
1985: Alan S Brody; M P Sorette; C A Gooding; J Listerud; M R Clark; W C Mentzer; R C Brasch; Tom L James
AUR memorial Award. Induced alignment of flowing sickle erythrocytes in a magnetic field. A preliminary report.
Investigative radiology 1985;20(6):560-6.
1985: N R Shine; E Bubienko; Tom L James
Interactions of diastereomeric tripeptides of lysyl-5-fluorotryptophyllysine with DNA. 2. Optical, 19F NMR, and strand cleavage studies of apurinic DNA complexes.
Biochemistry 1985;24(16):4341-5.
1985: N R Shine; Tom L James
Interactions of diastereomeric tripeptides of lysyl-5-fluorotryptophyllysine with DNA. 1. Optical and 19F NMR studies of native DNA complexes.
Biochemistry 1985;24(16):4333-41.
1985: M S Broido; Tom L James; G Zon; J W Keepers
Investigation of the solution structure of a DNA octamer [d(GGAATTCC)]2 using two-dimensional nuclear Overhauser enhancement spectroscopy.
European journal of biochemistry / FEBS 1985;150(1):117-28.
1985: S Wolff; Tom L James; G B Young; A R Margulis; J Bodycote; V Afzal
Magnetic resonance imaging: absence of in vitro cytogenetic damage.
Radiology 1985;155(1):163-5.
1985: M E Moseley; W M Chew; M C Nishimura; T L Richards; J Murphy-Boesch; G B Young; T M Marschner; Lawrence H Pitts; Tom L James
In vivo sodium-23 magnetic resonance surface coil imaging: observing experimental cerebral ischemia in the rat.
Magnetic resonance imaging 1985;3(4):383-7.
1985: D D Stark; M E Moseley; B R Bacon; A A Moss; H I Goldberg; N M Bass; Tom L James
Magnetic resonance imaging and spectroscopy of hepatic iron overload.
Radiology 1985;154(1):137-42.
1985: Tom L James
Phosphorus-31 NMR as a probe for phosphoproteins.
CRC critical reviews in biochemistry 1985;18(1):1-30.
1984: J W Keepers; P Schmidt; Tom L James; P A Kollman
Molecular-mechanical studies of the mismatched base analogs of d(CGCGAATTCGCG)2:d(CGTGAATTCGCG)2, d(CGAGAATTCGCG)2, d(CGCGAATTCACG)2, d(CGCGAATTCTCG)2, and d(CGCAGAATTCGCG).d(CGCGAATTCGCG).
Biopolymers 1984;23(12):2901-29.
1984: J Keepers; P A Kollman; Tom L James
Molecular mechanical studies of base-pair opening in d(CGCGC):d(GCGCG), dG5 . dC5, d(TATAT):d(ATATA), and dA5 . dT5 in the B and Z forms of DNA.
Biopolymers 1984;23(11 Pt 2):2499-511.
1984: A D Sherry; J Keepers; Tom L James; J Teherani
Methyl motions in 13C-methylated concanavalin as studied by 13C magnetic resonance relaxation techniques.
Biochemistry 1984;23(14):3181-5.
1984: M Gochin; Tom L James; R H Shafer
In vivo 19F-NMR of 5-fluorouracil incorporation into RNA and metabolites in Escherichia coli cells.
Biochimica et biophysica acta 1984;804(1):118-24.
1984: M S Broido; G Zon; Tom L James
Complete assignment of the non-exchangeable proton nmr resonances of [d-(GGAATTCC)]2 using two-dimensional nuclear overhauser effect spectra.
Biochemical and biophysical research communications 1984;119(2):663-70.
1984: M E Moseley; M C Nishimura; Lawrence H Pitts; H M Bartkowski; Tom L James
Proton nuclear magnetic resonance spectroscopy of normal and edematous brain tissue in vitro: changes in relaxation during tissue storage.
Magnetic resonance imaging 1984;2(3):205-9.
1983: A Delbarre; R H Shafer; Tom L James
19F-NMR study of DNA bis-intercalation.
Biopolymers 1983;22(12):2497-500.
1983: Alan Koretsky; S Wang; J Murphy-Boesch; M P Klein; Tom L James; Michael Weiner
31P NMR spectroscopy of rat organs, in situ, using chronically implanted radiofrequency coils.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(24):7491-5.
1983: P Bendel; J Murphy-Boesch; Tom L James
Deuterium NMR in the solid-state and in solution of the molecular motion of the bases in poly(I) and poly(I) . poly(C).
Biochimica et biophysica acta 1983;759(3):205-13.
1983: N Düzgüneş; J Wilschut; K Hong; R Fraley; C Perry; D S Friend; Tom L James; D Papahadjopoulos
Physicochemical characterization of large unilamellar phospholipid vesicles prepared by reverse-phase evaporation.
Biochimica et biophysica acta 1983;732(1):289-99.
1983: P Bendel; Tom L James
Structural and dynamic differences between supercoiled and linear DNA from proton NMR.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(11):3284-6.
1983: E Berman; Tom L James
13C-n.m.r.-spectral study of galactosyltransferase specificity with regard to the carbohydrate side-chain of native ovalbumin.
Carbohydrate research 1983;113(1):141-50.
1982: P H Bolton; G Clawson; V J Basus; Tom L James
Comparison of ribonucleic acid-protein interactions in messenger ribonucleoproteins, ribosomes, MS2 virus, and Q beta virus examined via phosphorus-31 nuclear magnetic resonance relaxation.
Biochemistry 1982;21(24):6073-81.
1982: A Taylor; S Sawan; Tom L James
Structural aspects of the inhibitor complex formed by N-(leucyl)-o-aminobenzenesulfonate and manganese with Zn2+-Mn2+ leucine aminopeptidase (EC 3.4.11.1). Studies by NMR.
The Journal of biological chemistry 1982;257(19):11571-6.
1982: J W Keepers; P A Kollman; P K Weiner; Tom L James
Molecular mechanical studies of DNA flexibility: coupled backbone torsion angles and base-pair openings.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(18):5537-41.
1982: P A Mirau; R H Shafer; Tom L James; P H Bolton
Fluoroquinacrine binding to nucleic acids: investigation of the 19F-NMR, optical, and fluorescence properties in the presence of DNA, poly(A), and tRNA.
Biopolymers 1982;21(5):909-21.
1982: W J Goux; C Perry; Tom L James
An NMR study of 13C-enriched galactose attached to the single carbohydrate chain of hen ovalbumin. Motions of the carbohydrates of glycoproteins.
The Journal of biological chemistry 1982;257(4):1829-35.
1982: P A Mirau; R H Shafer; Tom L James
Binding of 5-fluorotryptamine to polynucleotides as a model for protein-nucleic acid interactions: fluorine-19 nuclear magnetic resonance, absorption, and fluorescence studies.
Biochemistry 1982;21(4):615-20.
1981: P H Bolton; P A Mirau; R H Shafer; Tom L James
Interaction of the antimalarial drug fluoroquine with DNA, tRNA, and poly(A): 19F-NMR chemical-shift and relaxation, optical absorption, and fluorescence studies.
Biopolymers 1981;20(3):435-49.
1981: Tom L James; Dale E Edmondson; M Husain
Glucose oxidase contains a disubstituted phosphorus residue. Phosphorus-31 nuclear magnetic resonance studies of the flavin and nonflavin phosphate residues.
Biochemistry 1981;20(3):617-21.
1980: M E Nuss; Tom L James; M A Apple; P A Kollman
An NMR study of the interaction of daunomycin with dinucleotides and dinucleoside phosphates.
Biochimica et biophysica acta 1980;609(1):136-47.
1980: P H Bolton; Tom L James
Conformational mobility of deoxyribonucleic acid, transfer ribonucleic acid, and poly(adenylic acid) as monitored by carbon-13 nuclear magnetic resonance relaxation.
Biochemistry 1980;19(7):1388-92.
1979: M R Harkey; W L Settle; Tom L James; A J Trevor
Spectral studies on the interaction of dichloromethane with hemoglobin.
Molecular pharmacology 1979;16(3):1065-74.
1979: Dale E Edmondson; Tom L James
Covalently bound non-coenzyme phosphorus residues in flavoproteins: 31P nuclear magnetic resonance studies of Azotobacter flavodoxin.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(8):3786-9.
1979: Tom L James; R Matthews; G B Matson
Hemoglobin aggregation in oxygenated sickle cells studies by carbon-13 rotating frame spin-lattice relaxation in the presence of an off-resonance radiofrequency field.
Biopolymers 1979;18(7):1763-8.
1978: R W Fisher; Tom L James
Lateral diffusion of the phospholipid molecule in dipalmitoylphosphatidylcholine bilayers. An investigation using nuclear spin--lattice relaxation in the rotating frame.
Biochemistry 1978;17(7):1177-83.
1978: R M Matthews; Tom L James
Effect of dichloromethane on sickle cells. An in vitro water proton magnetic resonance relaxation study.
Biochemical and biophysical research communications 1978;80(4):879-85.
1977: A Zipp; I D Kuntz; Tom L James
Hemoglobin-water interactions in normal and sickle erythrocytes by proton magnetic resonance T1p measurements.
Archives of biochemistry and biophysics 1977;178(2):435-41.
1977: Tom L James
Measurements of water proton NMR spin-lattice relaxation time in the rotating frame (T1p) for studying motions in solutions of giant macro-molecules and supramolecular particles (T2 virus).
Physiological chemistry and physics 1977;9(2):161-6.
1976: Tom L James
Binding of adenosine 5'-diphosphate to creatine kinase. An investigation using intermolecular nuclear Overhauser effect measurements.
Biochemistry 1976;15(21):4724-30.
1976: Tom L James; A L Pogolotti; K M Ivanetich; Y Wataya; S S Lam; D V Santi
Thymidylate synthetase: fluorine-19 nmr characterization of the active site peptide covalently bound to 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate.
Biochemical and biophysical research communications 1976;72(2):404-10.
1976: A Zipp; Tom L James; I D Kuntz; S B Shohet
Water proton magnetic resonance studies of normal and sickle erythrocytes. Temperature and volume dependence.
Biochimica et biophysica acta 1976;428(2):291-303.
1974: Tom L James; M Cohn
Structural aspects of manganese-pyruvate kinase substrate and inhibitor complexes deduced from proton magnetic relaxation rates of pyruvate and a phosphoenolpyruvate analog.
The Journal of biological chemistry 1974;249(11):3519-26.
1974: F Ostroy; Tom L James; J H Noggle; A Sarrif; L E Hokin
Studies on the characterization of the sodium-potassium transport adenosinetriphosphatase. Nuclear magnetic resonance studies of 23Na binding to the purified and partially purified enzyme.
Archives of biochemistry and biophysics 1974;162(2):421-5.
1974: Tom L James; M Cohn
The role of the lysyl residue at the active site of creatine kinase. Nuclear Overhauser effect studies.
The Journal of biological chemistry 1974;249(8):2599-604.
1973: Tom L James; M L Ludwig; M Cohn
Dependence of the proton magnetic resonance spectra on the oxidation state of flavodoxin from Clostridium MP and from Peptostreptococcus elsdenii.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(12):3292-5.
1973: Tom L James; J Reuben; M Cohn
Nuclear magnetic resonance study of the binding of phosphoenolpyruvate and phosphoenol-alpha-ketobutyrate to manganese pyruvate kinase. Temperature, frequency,and monovalent cation dependence of water proton nuclear magnetic resonance relaxation rates.
The Journal of biological chemistry 1973;248(18):6443-9.
1972: Tom L James; K T Gillen
Nuclear magnetic resonance relaxation time and self-diffusion constant of water in hen egg white and yolk.
Biochimica et biophysica acta 1972;286(1):10-5.
1972: Tom L James; J H Noggle
23 Na NMR studies of sodium ion interactions: phosphatidyl serine, phosphoserine, and phosphoethanolamine.
Analytical biochemistry 1972;49(1):208-17.
1972: K H Mild; Tom L James; K T Gillen
Nuclear magnetic resonance relaxation time and self-diffusion coefficient measurements of water in frog ovarian eggs (Rana pipiens).
Journal of cellular physiology 1972;80(1):155-8.
1969: Tom L James; J H Noggle
23Na nuclear magnetic resonance relaxation studies of sodium ion interaction with soluble RNA.
Proceedings of the National Academy of Sciences of the United States of America 1969;62(3):644-9.