Peter van der Kraan

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Anatomy

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Intra-Articular Injections

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Blaney Davidson Esmeralda N; Remst Dennis F G; Vitters Elly L; van Beuningen Henk M; Blom Arjen B; Goumans Marie-Jose; van den Berg Wim B; van der Kraan Peter M
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
Hannink Gerjon; Piek Ester; Hendriks Jose M A; Van der Kraan Peter M; Schreurs B Willem; Buma Pieter
Biological effects of rinsing morsellised bone grafts before and after impaction.
Blom Arjen B; Brockbank Sarah M; van Lent Peter L; van Beuningen Henk M; Geurts Jeroen; Takahashi Nozomi; van der Kraan Peter M; van de Loo Fons A; Schreurs B Wim; Clements Kristen; Newham Peter; van den Berg Wim B
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.

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All Publications

2009: Blaney Davidson Esmeralda N; Remst Dennis F G; Vitters Elly L; van Beuningen Henk M; Blom Arjen B; Goumans Marie-Jose; van den Berg Wim B; van der Kraan Peter M
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7937-45.
2009: Hannink Gerjon; Piek Ester; Hendriks Jose M A; Van der Kraan Peter M; Schreurs B Willem; Buma Pieter
Biological effects of rinsing morsellised bone grafts before and after impaction.
International orthopaedics 2009;33(3):861-6.
2009: Blom Arjen B; Brockbank Sarah M; van Lent Peter L; van Beuningen Henk M; Geurts Jeroen; Takahashi Nozomi; van der Kraan Peter M; van de Loo Fons A; Schreurs B Wim; Clements Kristen; Newham Peter; van den Berg Wim B
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.
Arthritis and rheumatism 2009;60(2):501-12.
2008: van Lent P L E M; Grevers L C; Blom A B; Arntz O J; van de Loo F A J; van der Kraan P; Abdollahi-Roodsaz S; Srikrishna G; Freeze H; Sloetjes A; Nacken W; Vogl T; Roth J; van den Berg W B
Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis.
Arthritis and rheumatism 2008;58(12):3776-87.
2008: Nieminen Riina; Vuolteenaho Katriina; Riutta Asko; Kankaanranta Hannu; van der Kraan Peter M; Moilanen Teemu; Moilanen Eeva
Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability.
European journal of pharmacology 2008;587(1-3):309-16.
2008: van der Kraan Peter M; van den Berg Wim B
Osteoarthritis in the context of ageing and evolution. Loss of chondrocyte differentiation block during ageing.
Ageing research reviews 2008;7(2):106-13.
2007: Blaney Davidson E N; Vitters E L; van Beuningen H M; van de Loo F A J; van den Berg W B; van der Kraan P M
Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.
Arthritis and rheumatism 2007;56(12):4065-73.
2007: Hartog Anita; Leenders Inge; van der Kraan Peter M; Garssen Johan
Anti-inflammatory effects of orally ingested lactoferrin and glycine in different zymosan-induced inflammation models: evidence for synergistic activity.
International immunopharmacology 2007;7(13):1784-92.
2007: Yang Xuechao; van der Kraan Peter M; van den Dolder Juliette; Walboomers X Frank; Bian Zhuan; Fan Mingwen; Jansen John A
STRO-1 selected rat dental pulp stem cells transfected with adenoviral-mediated human bone morphogenetic protein 2 gene show enhanced odontogenic differentiation.
Tissue engineering 2007;13(11):2803-12.
2007: Blaney Davidson E N; van der Kraan P M; van den Berg W B
TGF-beta and osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2007;15(6):597-604.
2007: van der Kraan Peter M; van den Berg Wim B
Osteophytes: relevance and biology.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2007;15(3):237-44.
2007: Blom Arjen B; van der Kraan Peter M; van den Berg Wim B
Cytokine targeting in osteoarthritis.
Current drug targets 2007;8(2):283-92.
2007: Blom Arjen B; van Lent Peter L; Libregts Sten; Holthuysen Astrid E; van der Kraan Peter M; van Rooijen Nico; van den Berg Wim B
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Arthritis and rheumatism 2007;56(1):147-57.
2007: Blaney Davidson Esmeralda N; Vitters Elly L; van Lent Peter L E M; van de Loo Fons A J; van den Berg Wim B; van der Kraan Peter M
Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.
Arthritis research & therapy 2007;9(5):R102.
2006: Blaney Davidson E N; Vitters E L; van der Kraan P M; van den Berg W B
Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation.
Annals of the rheumatic diseases 2006;65(11):1414-21.
2006: Blaney Davidson E N; Vitters E L; Mooren F M; Oliver N; Berg W B van den; van der Kraan P M
Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage.
Arthritis and rheumatism 2006;54(5):1653-61.
2006: Blaney Davidson Esmeralda N; Vitters Elly L; van den Berg Wim B; van der Kraan Peter M
TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.
Arthritis research & therapy 2006;8(3):R65.
2005: Vuolteenaho K; Moilanen T; Jalonen U; Lahti A; Nieminen R; van Beuningen H M; van der Kraan P M; Moilanen E
TGFbeta inhibits IL-1 -induced iNOS expression and NO production in immortalized chondrocytes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2005;54(10):420-7.
2005: Takahashi N; Rieneck K; van der Kraan P M; van Beuningen H M; Vitters E L; Bendtzen K; van den Berg W B
Elucidation of IL-1/TGF-beta interactions in mouse chondrocyte cell line by genome-wide gene expression.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(5):426-38.
2005: Blaney Davidson E N; Scharstuhl A; Vitters E L; van der Kraan P M; van den Berg W B
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity.
Arthritis research & therapy 2005;7(6):R1338-47.
2004: Blom Arjen B; van Lent Peter L E M; Holthuysen Astrid E M; van der Kraan Peter M; Roth Johannes; van Rooijen Nico; van den Berg Wim B
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(8):627-35.
2004: van der Kraan Peter M; van de Loo Fons A J; van den Berg Wim B
Role of gene therapy in tissue engineering procedures in rheumatology: the use of animal models.
Biomaterials 2004;25(9):1497-504.
2004: van Lent P L E M; Blom A B; van der Kraan P; Holthuysen A E M; Vitters E; van Rooijen N; Smeets R L; Nabbe K C A M; van den Berg W B
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Arthritis and rheumatism 2004;50(1):103-11.
2003: Scharstuhl Alwin; Vitters Elly L; van der Kraan Peter M; van den Berg Wim B
Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis.
Arthritis and rheumatism 2003;48(12):3442-51.
2003: Scharstuhl A; Diepens R; Lensen J; Vitters E; van Beuningen H; van der Kraan P; van den Berg W
Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(11):773-82.
2003: Rudolphi K; Gerwin N; Verzijl N; van der Kraan P; van den Berg W
Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(10):738-46.
2003: Buma Pieter; Pieper Jeroen S; van Tienen Tony; van Susante Job L C; van der Kraan Peter M; Veerkamp Jacques H; van den Berg Wim B; Veth Rene P H; van Kuppevelt Toin H
Cross-linked type I and type II collagenous matrices for the repair of full-thickness articular cartilage defects--a study in rabbits.
Biomaterials 2003;24(19):3255-63.
2003: Scharstuhl Alwin; Glansbeek Harrie; Vitters Elly L; van der Kraan Peter M; van den Berg Wim B
Large scale protein production of the extracellular domain of the transforming growth factor-beta type II receptor using the Pichia pastoris expression system.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;786(1-2):271-7.
2002: van Beuningen H M; Stoop R; Buma P; Takahashi N; van der Kraan P M; van den Berg W B
Phenotypic differences in murine chondrocyte cell lines derived from mature articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(12):977-86.
2002: Scharstuhl A; van Beuningen H M; Vitters E L; van der Kraan P M; van den Berg W B
Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice.
Annals of the rheumatic diseases 2002;61(12):1095-8.
2002: van der Kraan P M; Buma P; van Kuppevelt T; van den Berg W B
Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(8):631-7.
2002: Pieper J S; van der Kraan P M; Hafmans T; Kamp J; Buma P; van Susante J L C; van den Berg W B; Veerkamp J H; van Kuppevelt T H
Crosslinked type II collagen matrices: preparation, characterization, and potential for cartilage engineering.
Biomaterials 2002;23(15):3183-92.
2002: Scharstuhl Alwin; Glansbeek Harrie L; van Beuningen Henk M; Vitters Elly L; van der Kraan Peter M; van den Berg Wim B
Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):507-14.
2001: van den Berg W B; van der Kraan P M; Scharstuhl A; van Beuningen H M
Growth factors and cartilage repair.
Clinical orthopaedics and related research 2001;(391 Suppl):S244-50.
2001: van Susante JLC; Pieper J; Buma P; van Kuppevelt T H; van Beuningen H; van Der Kraan P M; Veerkamp J H; van den Berg W B; Veth RPH
Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro.
Biomaterials 2001;22(17):2359-69.
2001: Stoop R; Buma P; van der Kraan P M; Hollander A P; Billinghurst R C; Meijers T H; Poole A R; van den Berg W B
Type II collagen degradation in articular cartilage fibrillation after anterior cruciate ligament transection in rats.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(4):308-15.
2001: Bakker A C; van de Loo F A; van Beuningen H M; Sime P; van Lent P L; van der Kraan P M; Richards C D; van den Berg W B
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(2):128-36.
2001: van der Kraan P M; Stoop R; Meijers T H; Poole A R; van den Berg W B
Expression of type X collagen in young and old C57Bl/6 and Balb/c mice. Relation with articular cartilage degeneration.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(2):92-100.
2000: Stoop R; Buma P; van der Kraan P M; Hollander A P; Clark Billinghurst R; Robin Poole A; van den Berg W B
Differences in type II collagen degradation between peripheral and central cartilage of rat stifle joints after cranial cruciate ligament transection.
Arthritis and rheumatism 2000;43(9):2121-31.
2000: van der Kraan P M; van den Berg W B
Anabolic and destructive mediators in osteoarthritis.
Current opinion in clinical nutrition and metabolic care 2000;3(3):205-11.
2000: van der Kraan P M; Vitters E L; van Beuningen H M; van de Loo F A; van den Berg W B
Role of nitric oxide in the inhibition of BMP-2-mediated stimulation of proteoglycan synthesis in articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(2):82-6.
2000: van Beuningen H M; Glansbeek H L; van der Kraan P M; van den Berg W B
Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(1):25-33.
1999: Stoop R; van der Kraan P M; Buma P; Hollander A P; Billinghurst R C; Poole A R; van den Berg W B
Type II collagen degradation in spontaneous osteoarthritis in C57Bl/6 and BALB/c mice.
Arthritis and rheumatism 1999;42(11):2381-9.
1999: van Meurs J; van Lent P; Stoop R; Holthuysen A; Singer I; Bayne E; Mudgett J; Poole R; Billinghurst C; van der Kraan P; Buma P; van den Berg W
Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
Arthritis and rheumatism 1999;42(10):2074-84.
1999: Stoop R; van der Kraan P M; Buma P; Hollander A P; Poole A R; van den Berg W B
Denaturation of type II collagen in articular cartilage in experimental murine arthritis. Evidence for collagen degradation in both reversible and irreversible cartilage damage.
The Journal of pathology 1999;188(3):329-37.
1998: van der Kraan P M; Vitters E L; Meijers T H; Poole A R; van den Berg W B
Collagen type I antisense and collagen type IIA messenger RNA is expressed in adult murine articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(6):417-26.
1998: van Beuningen H M; Glansbeek H L; van der Kraan P M; van den Berg W B
Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(5):306-17.
1998: Glansbeek H L; van Beuningen H M; Vitters E L; van der Kraan P M; van den Berg W B
Expression of recombinant human soluble type II transforming growth factor-beta receptor in Pichia pastoris and Escherichia coli: two powerful systems to express a potent inhibitor of transforming growth factor-beta.
Protein expression and purification 1998;12(2):201-7.
1998: Glansbeek H L; van Beuningen H M; Vitters E L; van der Kraan P M; van den Berg W B
Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-beta into murine knee joints.
Laboratory investigation; a journal of technical methods and pathology 1998;78(2):133-42.
1997: Glansbeek H L; van Beuningen H M; Vitters E L; Morris E A; van der Kraan P M; van den Berg W B
Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract interleukin-1alpha effects on proteoglycan synthesis and content.
Arthritis and rheumatism 1997;40(6):1020-8.
1997: Glansbeek H L; van der Kraan P M; Lafeber F P; Vitters E L; van den Berg W B
Species-specific expression of type II TGF-beta receptor isoforms by articular chondrocytes: effect of proteoglycan depletion and aging.
Cytokine 1997;9(5):347-51.
1997: van der Kraan P M; Glansbeek H L; Vitters E L; van den Berg W B
Early elevation of transforming growth factor-beta, decorin, and biglycan mRNA levels during cartilage matrix restoration after mild proteoglycan depletion.
The Journal of rheumatology 1997;24(3):543-9.
1997: Lafeber F P; van Roy H L; van der Kraan P M; van den Berg W B; Bijlsma J W
Transforming growth factor-beta predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage.
The Journal of rheumatology 1997;24(3):536-42.
1997: Van Meurs J B; Van Lent P L; Joosten L A; Van der Kraan P M; Van den Berg W B
Quantification of mRNA levels in joint capsule and articular cartilage of the murine knee joint by RT-PCR: kinetics of stromelysin and IL-1 mRNA levels during arthritis.
Rheumatology international 1997;16(5):197-205.
1996: van Osch G J; van der Kraan P M; Blankevoort L; Huiskes R; van den Berg W B
Relation of ligament damage with site specific cartilage loss and osteophyte formation in collagenase induced osteoarthritis in mice.
The Journal of rheumatology 1996;23(7):1227-32.
1996: van Osch G J; van der Kraan P M; van Valburg A A; van den Berg W B
The relation between cartilage damage and osteophyte size in a murine model for osteoarthritis in the knee.
Rheumatology international 1996;16(3):115-9.
1996: van Valburg A A; van Osch G J; van der Kraan P M; van den Berg W B
Quantification of morphometric changes in murine experimental osteoarthritis using image analysis.
Rheumatology international 1996;15(5):181-7.
1995: van Susante J L; Buma P; van Osch G J; Versleyen D; van der Kraan P M; van der Berg W B; Homminga G N
Culture of chondrocytes in alginate and collagen carrier gels.
Acta orthopaedica Scandinavica 1995;66(6):549-56.
1995: van Osch G J; Blankevoort L; van der Kraan P M; Janssen B; Hekman E; Huiskes R; van den Berg W B
Laxity characteristics of normal and pathological murine knee joints in vitro.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1995;13(5):783-91.
1995: Schuman L; Buma P; Versleyen D; de Man B; van der Kraan P M; van den Berg W B; Homminga G N
Chondrocyte behaviour within different types of collagen gel in vitro.
Biomaterials 1995;16(10):809-14.
1994: van der Kraan P M; de Lange J; Vitters E L; van Beuningen H M; van Osch G J; van Lent P L; van den Berg W B
Analysis of changes in proteoglycan content in murine articular cartilage using image analysis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1994;2(3):207-14.
1994: van Beuningen H M; van der Kraan P M; Arntz O J; van den Berg W B
In vivo protection against interleukin-1-induced articular cartilage damage by transforming growth factor-beta 1: age-related differences.
Annals of the rheumatic diseases 1994;53(9):593-600.
1994: van Beuningen H M; van der Kraan P M; Arntz O J; van den Berg W B
Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint.
Laboratory investigation; a journal of technical methods and pathology 1994;71(2):279-90.
1994: Verschure P J; Joosten L A; van der Kraan P M; Van den Berg W B
Responsiveness of articular cartilage from normal and inflamed mouse knee joints to various growth factors.
Annals of the rheumatic diseases 1994;53(7):455-60.
1994: van Osch G J; van der Kraan P M; van den Berg W B
Site specific inhibition of cartilage proteoglycan synthesis in the murine knee joint. Differences between 3 metabolic stimuli.
The Journal of rheumatology 1994;21(6):1107-12.
1994: Verschure P J; van der Kraan P M; Vitters E L; van den Berg W B
Stimulation of proteoglycan synthesis by triamcinolone acetonide and insulin-like growth factor 1 in normal and arthritic murine articular cartilage.
The Journal of rheumatology 1994;21(5):920-6.
1994: van Osch G J; van der Kraan P M; van den Berg W B
Site-specific cartilage changes in murine degenerative knee joint disease induced by iodoacetate and collagenase.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1994;12(2):168-75.
1993: Glansbeek H L; van der Kraan P M; Vitters E L; van den Berg W B
Correlation of the size of type II transforming growth factor beta (TGF-beta) receptor with TGF-beta responses of isolated bovine articular chondrocytes.
Annals of the rheumatic diseases 1993;52(11):812-6.
1993: van den Berg W B; van Osch G J; van der Kraan P M; van Beuningen H M
Cartilage destruction and osteophytes in instability-induced murine osteoarthritis: role of TGF beta in osteophyte formation?
Agents and actions 1993;40(3-4):215-9.
1993: van den Hoogen F H; van der Kraan P M; Boerbooms A M; van den Berg W B; van Lier H J; van de Putte L B
Effects of methotrexate on glycosaminoglycan production by scleroderma fibroblasts in culture.
Annals of the rheumatic diseases 1993;52(10):758-61.
1993: van der Kraan P M; Vitters E L; Postma N S; Verbunt J; van den Berg W B
Maintenance of the synthesis of large proteoglycans in anatomically intact murine articular cartilage by steroids and insulin-like growth factor I.
Annals of the rheumatic diseases 1993;52(10):734-41.
1993: Homminga G N; Buma P; Koot H W; van der Kraan P M; van den Berg W B
Chondrocyte behavior in fibrin glue in vitro.
Acta orthopaedica Scandinavica 1993;64(4):441-5.
1993: van Osch G J; van der Kraan P M; Vitters E L; Blankevoort L; van den Berg W B
Induction of osteoarthritis by intra-articular injection of collagenase in mice. Strain and sex related differences.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1993;1(3):171-7.
1993: van Osch G J; van der Kraan P M; van den Berg W B
In vivo quantification of proteoglycan synthesis in articular cartilage of different topographical areas in the murine knee joint.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(4):492-9.
1993: van Beuningen H M; van der Kraan P M; Arntz O J; van den Berg W B
Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor beta: studies in anatomically intact cartilage in vitro and in vivo.
Annals of the rheumatic diseases 1993;52(3):185-91.
1993: van Beuningen H M; van der Kraan P M; Arntz O J; van den Berg W B
Does TGF-beta protect articular cartilage in vivo?
Agents and actions. Supplements 1993;39():127-31.
1993: Glansbeek H L; van der Kraan P M; Vitters E L; van den Berg W B
Variable TGF-beta receptor expression regulates TGF-beta responses of articular chondrocytes.
Agents and actions. Supplements 1993;39():139-45.
1992: Buma P; Verschuren C; Versleyen D; Van der Kraan P; Oestreicher A B
Calcitonin gene-related peptide, substance P and GAP-43/B-50 immunoreactivity in the normal and arthrotic knee joint of the mouse.
Histochemistry 1992;98(5):327-39.
1992: Lafeber F P; van der Kraan P M; van Roy H L; Vitters E L; Huber-Bruning O; van den Berg W B; Bijlsma J W
Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.
The American journal of pathology 1992;140(6):1421-9.
1992: van der Kraan P M; Vitters E L; van Beuningen H M; van den Berg W B
Proteoglycan synthesis and osteophyte formation in 'metabolically' and 'mechanically' induced murine degenerative joint disease: an in-vivo autoradiographic study.
International journal of experimental pathology 1992;73(3):335-50.
1992: van der Kraan P M; Vitters E L; van den Berg W B
Inhibition of proteoglycan synthesis by transforming growth factor beta in anatomically intact articular cartilage of murine patellae.
Annals of the rheumatic diseases 1992;51(5):643-7.
1992: van der Kraan P; Vitters E; van den Berg W
Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes.
The Journal of rheumatology 1992;19(1):140-5.
1990: van der Kraan P M; Vitters E L; de Vries B J; van den Berg W B
High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1990;8(4):565-71.
1990: van der Kraan P M; Vitters E L; de Vries B J; van den Berg W B; van de Putte L B
The effect of chronic paracetamol administration to rats on the glycosaminoglycan content of patellar cartilage.
Agents and actions 1990;29(3-4):218-23.
1990: de Vries B J; van der Kraan P M; van den Berg W B
Decrease of inorganic blood sulfate following treatment with selected antirheumatic drugs: potential consequence for articular cartilage.
Agents and actions 1990;29(3-4):224-31.
1990: van der Kraan P M; Vitters E L; van Beuningen H M; van de Putte L B; van den Berg W B
Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis.
Journal of experimental pathology (Oxford, England) 1990;71(1):19-31.
1989: van der Kraan P M; Vitters E L; van de Putte L B; van den Berg W B
Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints.
The American journal of pathology 1989;135(6):1001-14.
1989: van der Kraan P M; de Vries B J; Vitters E L; van den Berg W B; van de Putte L B
The effect of low sulfate concentrations on the glycosaminoglycan synthesis in anatomically intact articular cartilage of the mouse.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1989;7(5):645-53.
1988: van der Kraan P M; de Vries B J; Vitters E L; van den Berg W B; van de Putte L B
Inhibition of glycosaminoglycan synthesis in anatomically intact rat patellar cartilage by paracetamol-induced serum sulfate depletion.
Biochemical pharmacology 1988;37(19):3683-90.
1988: van der Kraan P M; van Zandvoort P M; De Abreu R A; Bakkeren J A
Effects of 8-aminoguanosine on the toxicity of guanosine and deoxyguanosine for malignant and normal lymphoid cells.
Journal of leukocyte biology 1988;44(1):46-50.
1988: van der Kraan P M; Vitters E L; de Vries B J; van den Berg W B; van de Putte L B
Synthesis of aberrant glycosaminoglycans during cartilage culture in 'sulfate free' medium.
Journal of biochemical and biophysical methods 1988;15(5):273-7.
1988: van der Kraan P M; de Vries B J; van den Berg W B; Vitters E; van de Putte L B
Effects of drug-mediated serum sulfate depletion on glycosaminoglycan synthesis.
Agents and actions 1988;23(1-2):55-7.
1987: van der Kraan P M; van Zandvoort P M; De Abreu R A; van Baal J M; Bakkeren J A
Inhibition of lymphoid cell growth by adenine ribonucleotide accumulation. The role of phosphoribosylpyrophosphate-depletion induced pyrimidine starvation.
Biochimica et biophysica acta 1987;927(2):213-21.
1986: van der Kraan P M; van Zandvoort P M; De Abreu R A; Bakkeren J A; van Laarhoven J P; de Bruyn C H
Inhibition of 3H-thymidine incorporation by guanosine and deoxyguanosine in human lymphoid cells.
Advances in experimental medicine and biology 1986;195 Pt A():547-51.
1986: van der Kraan P M; van Zandvoort P M; De Abreu R A; Bakkeren J A; van Laarhoven J P; de Bruyn C H
Biphasic effect of adenosine on cell growth and cell cycle of human lymphoid cell lines.
Advances in experimental medicine and biology 1986;195 Pt A():553-9.

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