Pal Pacher

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Anatomy

Physiology

Enzyme Activation

Co-author Network

Publications

TOP 3
Sergey Lupachyk; Roman Stavniichuk; Julia I Komissarenko; Viktor R Drel; Alexander A Obrosov; Azza B El-Remessy; Pal Pacher; Irina G Obrosova
Na⁺/H⁺-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis.
Viktor R Drel; Pal Pacher; Roman Stavniichuk; Weizheng Xu; Jie Zhang; Tamara M Kuchmerovska; Barbara Slusher; Irina G Obrosova
Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice.
Jon Mabley; Sevelanne Gordon; Pal Pacher
Nicotine exerts an anti-inflammatory effect in a murine model of acute lung injury.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Pal Pacher (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Sergey Lupachyk; Roman Stavniichuk; Julia I Komissarenko; Viktor R Drel; Alexander A Obrosov; Azza B El-Remessy; Pal Pacher; Irina G Obrosova
Na⁺/H⁺-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis.
International journal of molecular medicine 2012;29(6):989-98.
2011: Viktor R Drel; Pal Pacher; Roman Stavniichuk; Weizheng Xu; Jie Zhang; Tamara M Kuchmerovska; Barbara Slusher; Irina G Obrosova
Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice.
International journal of molecular medicine 2011;28(4):629-35.
2011: Jon Mabley; Sevelanne Gordon; Pal Pacher
Nicotine exerts an anti-inflammatory effect in a murine model of acute lung injury.
Inflammation 2011;34(4):231-7.
2011: P Pacher; R Mechoulam
Is lipid signaling through cannabinoid 2 receptors part of a protective system?
Progress in lipid research 2011;50(2):193-211.
2011: Pierre Watcho; Roman Stavniichuk; Pierre Tane; Hanna Shevalye; Yury Maksimchyk; Pal Pacher; Irina G Obrosova
Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice.
International journal of molecular medicine 2011;27(3):299-307.
2011: Noureddine Loukili; Nathalie Rosenblatt-Velin; Jianhui Li; Stéphanie Clerc; Pal Pacher; François Feihl; Bernard Waeber; Lucas Liaudet
Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo.
Cardiovascular research 2011;89(3):586-94.
2010: Mohanraj Rajesh; Partha Mukhopadhyay; Sándor Bátkai; Vivek Patel; Keita Saito; Shingo Matsumoto; Yoshihiro Kashiwaya; Béla Horváth; Bani Mukhopadhyay; Lauren Becker; et al.
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
Journal of the American College of Cardiology 2010;56(25):2115-25.
2010: Li Jianhui; Nathalie Rosenblatt-Velin; Noureddine Loukili; Pal Pacher; François Feihl; Bernard Waeber; Lucas Liaudet
Endotoxin impairs cardiac hemodynamics by affecting loading conditions but not by reducing cardiac inotropism.
American journal of physiology. Heart and circulatory physiology 2010;299(2):H492-501.
2010: Leonóra Himer; Balázs Csóka; Zsolt Selmeczy; Balázs Koscsó; Tímea Pócza; Pál Pacher; Zoltán H Németh; Edwin A Deitch; E Sylvester Vizi; Bruce N Cronstein; et al.
Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(8):2631-40.
2010: Irina G Obrosova; Yury Maksimchyk; Pal Pacher; Elisabet Agardh; Maj-Lis Smith; Azza B El-Remessy; Carl-David Agardh
Evaluation of the aldose reductase inhibitor fidarestat on ischemia-reperfusion injury in rat retina.
International journal of molecular medicine 2010;26(1):135-42.
2010: Balázs Csóka; Zoltán H Németh; Peter Rosenberger; Holger K Eltzschig; Zoltán Spolarics; Pál Pacher; Zsolt Selmeczy; Balázs Koscsó; Leonóra Himer; E Sylvester Vizi; et al.
A2B adenosine receptors protect against sepsis-induced mortality by dampening excessive inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):542-50.
2010: Noureddine Loukili; Nathalie Rosenblatt-Velin; Joëlle Rolli; Sandra Levrand; François Feihl; Bernard Waeber; Pal Pacher; Lucas Liaudet
Oxidants positively or negatively regulate nuclear factor kappaB in a context-dependent manner.
The Journal of biological chemistry 2010;285(21):15746-52.
2010: Norio Horiguchi; Fouad Lafdil; Andrew M Miller; Ogyi Park; Hua Wang; Mohanraj Rajesh; Partha Mukhopadhyay; Xin Yuan Fu; Pal Pacher; Bin Gao
Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell-specific signal transducer and activator of transcription 3 gene knockout mice.
Hepatology (Baltimore, Md.) 2010;51(5):1724-34.
2010: Andrew M Miller; Hua Wang; Ogyi Park; Norio Horiguchi; Fouad Lafdil; Partha Mukhopadhyay; Akira Moh; Xin Yuan Fu; George Kunos; Pal Pacher; et al.
Anti-inflammatory and anti-apoptotic roles of endothelial cell STAT3 in alcoholic liver injury.
Alcoholism, clinical and experimental research 2010;34(4):719-25.
2010: Partha Mukhopadhyay; Mohanraj Rajesh; Sándor Bátkai; Vivek Patel; Yoshihiro Kashiwaya; Lucas Liaudet; Oleg V Evgenov; Ken Mackie; György Haskó; Pál Pacher
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Cardiovascular research 2010;85(4):773-84.
2010: Partha Mukhopadhyay; Mohanraj Rajesh; Hao Pan; Vivek Patel; Bani Mukhopadhyay; Sándor Bátkai; Bin Gao; György Haskó; Pál Pacher
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.
Free radical biology & medicine 2010;48(3):457-67.
2010: Partha Mukhopadhyay; Subhendu Mukherjee; Kaimul Ahsan; Angshuman Bagchi; Pal Pacher; Dipak K Das
Restoration of altered microRNA expression in the ischemic heart with resveratrol.
PloS one 2010;5(12):e15705.
2010: Joelle Rolli; Nathalie Rosenblatt-Velin; Jianhui Li; Noureddine Loukili; Sandra Levrand; Pal Pacher; Bernard Waeber; François Feihl; Patrick Ruchat; Lucas Liaudet
Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction.
PloS one 2010;5(9):e12687.
2010: Joëlle Rolli; Noureddine Loukili; Sandra Levrand; Nathalie Rosenblatt-Velin; Stéphanie Rignault-Clerc; Bernard Waeber; François Feihl; Pal Pacher; Lucas Liaudet
Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.
Critical care (London, England) 2010;14(4):R160.
2009: Zoltan Ungvari; Nazar Labinskyy; Partha Mukhopadhyay; John T Pinto; Zsolt Bagi; Praveen Ballabh; Cuihua Zhang; Pal Pacher; Anna Csiszar
Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells.
American journal of physiology. Heart and circulatory physiology 2009;297(5):H1876-81.
2009: Jon G Mabley; Pal Pacher; Kanneganti G K Murthy; William Williams; Garry J Southan; Andrew L Salzman; Csaba Szabo
The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.
Shock (Augusta, Ga.) 2009;32(3):258-62.
2009: Tamás Bíró; Balázs I Tóth; György Haskó; Ralf Paus; Pál Pacher
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities.
Trends in pharmacological sciences 2009;30(8):411-20.
2009: Anna Csiszar; Nazar Labinskyy; John T Pinto; Praveen Ballabh; Hanrui Zhang; Gyorgy Losonczy; Kevin Pearson; Rafael de Cabo; Pal Pacher; Cuihua Zhang; et al.
Resveratrol induces mitochondrial biogenesis in endothelial cells.
American journal of physiology. Heart and circulatory physiology 2009;297(1):H13-20.
2009: György Haskó; Balázs Csóka; Zoltán H Németh; E Sylvester Vizi; Pál Pacher
A(2B) adenosine receptors in immunity and inflammation.
Trends in immunology 2009;30(6):263-70.
2009: Igor Vareniuk; Pal Pacher; Ivan A Pavlov; Viktor R Drel; Irina G Obrosova
Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency.
International journal of molecular medicine 2009;23(5):571-80.
2009: Partha Mukhopadhyay; Mohanraj Rajesh; Sándor Bátkai; Yoshihiro Kashiwaya; György Haskó; Lucas Liaudet; Csaba Szabó; Pál Pacher
Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.
American journal of physiology. Heart and circulatory physiology 2009;296(5):H1466-83.
2009: Jon G Mabley; Pal Pacher; Csaba Szabo
Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.
Molecular medicine (Cambridge, Mass.) 2009;15(5-6):166-72.
2009: Nazar Labinskyy; Partha Mukhopadhyay; Janos Toth; Gabor Szalai; Monika Veres; Gyorgy Losonczy; John T Pinto; Pal Pacher; Praveen Ballabh; Andrej Podlutsky; et al.
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
American journal of physiology. Heart and circulatory physiology 2009;296(4):H946-56.
2009: Hao Pan; Zhoujun Shen; Partha Mukhopadhyay; Hua Wang; Pal Pacher; Xuebin Qin; Bin Gao
Anaphylatoxin C5a contributes to the pathogenesis of cisplatin-induced nephrotoxicity.
American journal of physiology. Renal physiology 2009;296(3):F496-504.
2009: Hao Pan; Partha Mukhopadhyay; Mohanraj Rajesh; Vivek Patel; Bani Mukhopadhyay; Bin Gao; György Haskó; Pál Pacher
Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death.
The Journal of pharmacology and experimental therapeutics 2009;328(3):708-14.
2009: Balázs Csóka; Zoltán H Németh; Partha Mukhopadhyay; Zoltán Spolarics; Mohanraj Rajesh; Stephanie Federici; Edwin A Deitch; Sándor Bátkai; Pál Pacher; György Haskó
CB2 cannabinoid receptors contribute to bacterial invasion and mortality in polymicrobial sepsis.
PloS one 2009;4(7):e6409.
2009: Lucas Liaudet; Giuseppe Vassalli; Pal Pacher
Role of peroxynitrite in the redox regulation of cell signal transduction pathways.
Frontiers in bioscience : a journal and virtual library 2009;14():4809-14.
2009: Anna Csiszar; Andrej Podlutsky; Michael S Wolin; Gyorgy Losonczy; Pal Pacher; Zoltan Ungvari
Oxidative stress and accelerated vascular aging: implications for cigarette smoking.
Frontiers in bioscience : a journal and virtual library 2009;14():3128-44.
2008: Mohanraj Rajesh; Partha Mukhopadhyay; György Haskó; Pál Pacher
Cannabinoid CB1 receptor inhibition decreases vascular smooth muscle migration and proliferation.
Biochemical and biophysical research communications 2008;377(4):1248-52.
2008: Anna Csiszar; Nazar Labinskyy; Viviana Perez; Fabio A Recchia; Andrej Podlutsky; Partha Mukhopadhyay; Gyorgy Losonczy; Pal Pacher; Steven N Austad; Andrzej Bartke; et al.
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
American journal of physiology. Heart and circulatory physiology 2008;295(5):H1882-94.
2008: Pál Pacher; Kumar Sharma; György Csordás; Yanqing Zhu; György Hajnóczky
Uncoupling of ER-mitochondrial calcium communication by transforming growth factor-beta.
American journal of physiology. Renal physiology 2008;295(5):F1303-12.
2008: Kwan-Hoon Moon; Brian L Hood; Partha Mukhopadhyay; Mohanraj Rajesh; Mohamed A Abdelmegeed; Yong-Il Kwon; Thomas P Conrads; Timothy D Veenstra; Byoung-Joon Song; Pal Pacher
Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion.
Gastroenterology 2008;135(4):1344-57.
2008: Balázs Csóka; Leonóra Himer; Zsolt Selmeczy; E Sylvester Vizi; Pál Pacher; Catherine Ledent; Edwin A Deitch; Zoltán Spolarics; Zoltán H Németh; György Haskó
Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(10):3491-9.
2008: Zoltan Ungvari; Boris F Krasnikov; Anna Csiszar; Nazar Labinskyy; Partha Mukhopadhyay; Pal Pacher; Arthur J L Cooper; Natalia Podlutskaya; Steven N Austad; Andrej Podlutsky
Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency.
Age (Dordrecht, Netherlands) 2008;30(2-3):121-33.
2008: György Haskó; Joel Linden; Bruce Cronstein; Pál Pacher
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases.
Nature reviews. Drug discovery 2008;7(9):759-70.
2008: Jon G Mabley; Pal Pacher; Kanneganti G K Murthy; William Williams; Garry J Southan; Andrew L Salzman; Csaba Szabo
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
The Journal of endocrinology 2008;198(3):581-9.
2008: Pal Pacher; Csaba Szabo
Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease.
The American journal of pathology 2008;173(1):2-13.
2008: Viktor R Drel; Pal Pacher; Tayyeba K Ali; Jeho Shin; Ulrich Julius; Azza B El-Remessy; Irina G Obrosova
Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.
International journal of molecular medicine 2008;21(6):667-76.
2008: Anna Csiszar; Nazar Labinskyy; Andrej Podlutsky; Pawel M Kaminski; Michael S Wolin; Cuihua Zhang; Partha Mukhopadhyay; Pal Pacher; Furong Hu; Rafael de Cabo; et al.
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2721-35.
2008: Stefan Engeli; Karsten Heusser; Jürgen Janke; Kerstin Gorzelniak; Sándor Bátkai; Pál Pacher; Judith Harvey-White; Friedrich C Luft; Jens Jordan
Peripheral endocannabinoid system activity in patients treated with sibutramine.
Obesity (Silver Spring, Md.) 2008;16(5):1135-7.
2008: Norio Horiguchi; Lei Wang; Partha Mukhopadhyay; Ogyi Park; Won Il Jeong; Fouad Lafdil; Douglas Osei-Hyiaman; Akira Moh; Xin Yuan Fu; Pál Pacher; et al.
Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury.
Gastroenterology 2008;134(4):1148-58.
2008: Pál Pacher; Bin Gao
Endocannabinoids and liver disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(4):G850-4.
2008: Pal Pacher
Poly(ADP-ribose) polymerase inhibition as a novel therapeutic approach against intraepidermal nerve fiber loss and neuropathic pain associated with advanced diabetic neuropathy: a commentary on "PARP Inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy".
Free radical biology & medicine 2008;44(6):969-71.
2008: György Haskó; Pál Pacher
A2A receptors in inflammation and injury: lessons learned from transgenic animals.
Journal of leukocyte biology 2008;83(3):447-55.
2008: Cs Lengyel; L Virág; P P Kovács; A Kristóf; P Pacher; E Kocsis; Zs M Koltay; P P Nánási; M Tóth; V Kecskeméti; et al.
Role of slow delayed rectifier K+-current in QT prolongation in the alloxan-induced diabetic rabbit heart.
Acta physiologica (Oxford, England) 2008;192(3):359-68.
2008: Christoph W Michalski; Florian E Oti; Mert Erkan; Danguole Sauliunaite; Frank Bergmann; Pal Pacher; Sandor Batkai; Michael W Müller; Nathalia A Giese; Helmut Friess; et al.
Cannabinoids in pancreatic cancer: correlation with survival and pain.
International journal of cancer. Journal international du cancer 2008;122(4):742-50.
2008: Pál Pacher; Takahiro Nagayama; Partha Mukhopadhyay; Sándor Bátkai; David A Kass
Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats.
Nature protocols 2008;3(9):1422-34.
2008: Christoph W Michalski; Milena Maier; Mert Erkan; Danguole Sauliunaite; Frank Bergmann; Pal Pacher; Sandor Batkai; Nathalia A Giese; Thomas Giese; Helmut Friess; et al.
Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells.
PloS one 2008;3(2):e1701.
2008: P Pacher; G Haskó
Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning.
British journal of pharmacology 2008;153(2):252-62.
2008: M Rajesh; P Mukhopadhyay; G Haskó; J W Huffman; K Mackie; P Pacher
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration.
British journal of pharmacology 2008;153(2):347-57.
2008: Zsolt Selmeczy; E Sylvester Vizi; Balázs Csóka; Pál Pacher; György Haskó
Role of nonsynaptic communication in regulating the immune response.
Neurochemistry international 2008;52(1-2):52-9.
2007: Viktor R Drel; Pal Pacher; Igor Vareniuk; Ivan A Pavlov; Olga Ilnytska; Valeriy V Lyzogubov; Seth R Bell; John T Groves; Irina G Obrosova
Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.
International journal of molecular medicine 2007;20(6):783-92.
2007: Mohanraj Rajesh; Hao Pan; Partha Mukhopadhyay; Sándor Bátkai; Douglas Osei-Hyiaman; György Haskó; Lucas Liaudet; Bin Gao; Pál Pacher
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
Journal of leukocyte biology 2007;82(6):1382-9.
2007: Mohanraj Rajesh; Partha Mukhopadhyay; Sándor Bátkai; György Haskó; Lucas Liaudet; John W Huffman; Anna Csiszar; Zoltan Ungvari; Ken Mackie; Subroto Chatterjee; et al.
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2210-8.
2007: Balázs Csóka; Zoltán H Németh; László Virág; Pál Gergely; S Joseph Leibovich; Pál Pacher; Chun-Xiao Sun; Michael R Blackburn; E Sylvester Vizi; Edwin A Deitch; et al.
A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coli.
Blood 2007;110(7):2685-95.
2007: Balázs Csóka; Zoltán H Németh; Zsolt Selmeczy; Balázs Koscsó; Pál Pacher; E Sylvester Vizi; Edwin A Deitch; György Haskó
Role of A(2A) adenosine receptors in regulation of opsonized E. coli-induced macrophage function.
Purinergic signalling 2007;3(4):447-52.
2007: Sándor Bátkai; Partha Mukhopadhyay; Judith Harvey-White; Raouf Kechrid; Pál Pacher; George Kunos
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1689-95.
2007: Viktor R Drel; Pal Pacher; Igor Vareniuk; Ivan Pavlov; Olga Ilnytska; Valeriy V Lyzogubov; Jyoti Tibrewala; John T Groves; Irina G Obrosova
A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.
European journal of pharmacology 2007;569(1-2):48-58.
2007: Partha Mukhopadhyay; Sándor Bátkai; Mohanraj Rajesh; Nora Czifra; Judith Harvey-White; György Haskó; Zsuzsanna Zsengeller; Norma P Gerard; Lucas Liaudet; George Kunos; et al.
Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity.
Journal of the American College of Cardiology 2007;50(6):528-36.
2007: Sandra Levrand; Pal Pacher; Benoît Pesse; Joelle Rolli; François Feihl; Bernard Waeber; Lucas Liaudet
Homocysteine induces cell death in H9C2 cardiomyocytes through the generation of peroxynitrite.
Biochemical and biophysical research communications 2007;359(3):445-50.
2007: Sándor Bátkai; Mohanraj Rajesh; Partha Mukhopadhyay; György Haskó; Lucas Liaudet; Benjamin F Cravatt; Anna Csiszár; Zoltan Ungvári; Pál Pacher
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.
American journal of physiology. Heart and circulatory physiology 2007;293(2):H909-18.
2007: Zoltán H Németh; David Bleich; Balázs Csóka; Pál Pacher; Jon G Mabley; Leonóra Himer; E Sylvester Vizi; Edwin A Deitch; Csaba Szabó; Bruce N Cronstein; et al.
Adenosine receptor activation ameliorates type 1 diabetes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2379-88.
2007: Nitin Agarwal; Pal Pacher; Irmgard Tegeder; Fumimasa Amaya; Cristina E Constantin; Gary J Brenner; Tiziana Rubino; Christoph W Michalski; Giovanni Marsicano; Krisztina Monory; et al.
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Nature neuroscience 2007;10(7):870-9.
2007: Mohanraj Rajesh; Partha Mukhopadhyay; Sándor Bátkai; György Haskó; Lucas Liaudet; Viktor R Drel; Irina G Obrosova; Pál Pacher
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H610-9.
2007: Partha Mukhopadhyay; Mohanraj Rajesh; Kashiwaya Yoshihiro; György Haskó; Pál Pacher
Simple quantitative detection of mitochondrial superoxide production in live cells.
Biochemical and biophysical research communications 2007;358(1):203-8.
2007: Jon G Mabley; Rebecca Wallace; Pál Pacher; Kanneganti Murphy; Csaba Szabó
Inhibition of poly(adenosine diphosphate-ribose) polymerase by the active form of vitamin D.
International journal of molecular medicine 2007;19(6):947-52.
2007: Sándor Bátkai; Douglas Osei-Hyiaman; Hao Pan; Osama El-Assal; Mohanraj Rajesh; Partha Mukhopadhyay; Feng Hong; Judith Harvey-White; Anjum Jafri; György Haskó; et al.
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1788-800.
2007: Z Selmeczy; B Csóka; P Pacher; E S Vizi; G Haskó
The adenosine A2A receptor agonist CGS 21680 fails to ameliorate the course of dextran sulphate-induced colitis in mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007;56(5):204-9.
2007: Christoph W Michalski; Tamara Laukert; Danguole Sauliunaite; Pál Pacher; Frank Bergmann; Nitin Agarwal; Yun Su; Thomas Giese; Nathalia A Giese; Sándor Bátkai; et al.
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis.
Gastroenterology 2007;132(5):1968-78.
2007: György Haskó; Pál Pacher; Edwin A Deitch; E Sylvester Vizi
Shaping of monocyte and macrophage function by adenosine receptors.
Pharmacology & therapeutics 2007;113(2):264-75.
2007: Pál Pacher; Csaba Szabó
Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors.
Cardiovascular drug reviews 2007;25(3):235-60.
2007: Partha Mukhopadhyay; Mohanraj Rajesh; György Haskó; Brian J Hawkins; Muniswamy Madesh; Pál Pacher
Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy.
Nature protocols 2007;2(9):2295-301.
2007: Pál Pacher; Joseph S Beckman; Lucas Liaudet
Nitric oxide and peroxynitrite in health and disease.
Physiological reviews 2007;87(1):315-424.
2006: Csaba Szabo; Pal Pacher; Raymond A Swanson
Novel modulators of poly(ADP-ribose) polymerase.
Trends in pharmacological sciences 2006;27(12):626-30.
2006: Mohanraj Rajesh; Partha Mukhopadhyay; Grzegorz Godlewski; Sándor Bátkai; György Haskó; Lucas Liaudet; Pál Pacher
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Biochemical and biophysical research communications 2006;350(4):1056-62.
2006: Mohanraj Rajesh; Partha Mukhopadhyay; Sándor Bátkai; Grzegorz Godlewski; György Haskó; Lucas Liaudet; Pál Pacher
Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis.
Biochemical and biophysical research communications 2006;350(2):352-7.
2006: Matthias Blüher; Stefan Engeli; Nora Klöting; Janin Berndt; Mathias Fasshauer; Sándor Bátkai; Pál Pacher; Michael R Schön; Jens Jordan; Michael Stumvoll
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity.
Diabetes 2006;55(11):3053-60.
2006: I G Obrosova; V R Drel; A K Kumagai; C Szábo; P Pacher; M J Stevens
Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models.
Diabetologia 2006;49(10):2525-33.
2006: Sandra Levrand; Christine Vannay-Bouchiche; Benoît Pesse; Pal Pacher; François Feihl; Bernard Waeber; Lucas Liaudet
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo.
Free radical biology & medicine 2006;41(6):886-95.
2006: Pál Pacher; Sándor Bátkai; George Kunos
The endocannabinoid system as an emerging target of pharmacotherapy.
Pharmacological reviews 2006;58(3):389-462.
2006: Oleg V Evgenov; Pál Pacher; Peter M Schmidt; György Haskó; Harald H H W Schmidt; Johannes-Peter Stasch
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential.
Nature reviews. Drug discovery 2006;5(9):755-68.
2006: Olga Ilnytska; Valeriy V Lyzogubov; Martin J Stevens; Viktor R Drel; Nazar Mashtalir; Pal Pacher; Mark A Yorek; Irina G Obrosova
Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.
Diabetes 2006;55(6):1686-94.
2006: Zoltán H Németh; Balázs Csóka; Jeanette Wilmanski; Dazhong Xu; Qi Lu; Catherine Ledent; Edwin A Deitch; Pál Pacher; Zoltán Spolarics; György Haskó
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5616-26.
2006: Viktor R Drel; Pal Pacher; Martin J Stevens; Irina G Obrosova
Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.
Free radical biology & medicine 2006;40(8):1454-65.
2006: Pál Pacher; Csaba Szabó
Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes.
Current opinion in pharmacology 2006;6(2):136-41.
2006: Pál Pacher; Alex Nivorozhkin; Csaba Szabó
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Pharmacological reviews 2006;58(1):87-114.
2006: Garry Milman; Yehoshua Maor; Saleh Abu-Lafi; Michal Horowitz; Ruth Gallily; Sandor Batkai; Fong-Ming Mo; Laszlo Offertaler; Pal Pacher; George Kunos; et al.
N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2428-33.
2006: Pál Pacher; Lucas Liaudet; Jon G Mabley; Attila Cziráki; György Haskó; Csaba Szabó
Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure.
International journal of molecular medicine 2006;17(2):369-75.
2006: Nazar Labinskyy; Anna Csiszar; Gabor Veress; Gyorgyi Stef; Pal Pacher; Gabor Oroszi; Joseph Wu; Zoltan Ungvari
Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.
Current medicinal chemistry 2006;13(9):989-96.
2005: Zoltán H Németh; Carol S Lutz; Balázs Csóka; Edwin A Deitch; S Joseph Leibovich; William C Gause; Masahide Tone; Pál Pacher; E Sylvester Vizi; György Haskó
Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):8260-70.
2005: Irina G Obrosova; Viktor R Drel; Pal Pacher; Olga Ilnytska; Zhong Q Wang; Martin J Stevens; Mark A Yorek
Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.
Diabetes 2005;54(12):3435-41.
2005: Pál Pacher; Csaba Szabó
Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.
Antioxidants & redox signaling 2005;7(11-12):1568-80.
2005: Sandra Levrand; Benoît Pesse; François Feihl; Bernard Waeber; Pal Pacher; Joëlle Rolli; Marie-Denise Schaller; Lucas Liaudet
Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines.
The Journal of biological chemistry 2005;280(41):34878-87.
2005: Stefan Engeli; Jana Böhnke; Mareike Feldpausch; Kerstin Gorzelniak; Jürgen Janke; Sándor Bátkai; Pál Pacher; Judy Harvey-White; Friedrich C Luft; Arya M Sharma; et al.
Activation of the peripheral endocannabinoid system in human obesity.
Diabetes 2005;54(10):2838-43.
2005: Patrizio Pascale; Mauro Oddo; Pal Pacher; Marc Augsburger; Lucas Liaudet
Severe rhabdomyolysis following venlafaxine overdose.
Therapeutic drug monitoring 2005;27(5):562-4.
2005: György Haskó; Pál Pacher; E Sylvester Vizi; Peter Illes
Adenosine receptor signaling in the brain immune system.
Trends in pharmacological sciences 2005;26(10):511-6.
2005: Pál Pacher; Sándor Bátkai; George Kunos
Cirrhotic cardiomyopathy: an endocannabinoid connection?
British journal of pharmacology 2005;146(3):313-4.
2005: Caroline Ojaimi; Wei Li; Shintaro Kinugawa; Heiner Post; Anna Csiszar; Pal Pacher; Gabor Kaley; Thomas H Hintze
Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.
American journal of physiology. Heart and circulatory physiology 2005;289(4):H1399-407.
2005: Pál Pacher; Sándor Bátkai; Douglas Osei-Hyiaman; László Offertáler; Jie Liu; Judy Harvey-White; Attila Brassai; Zoltán Járai; Benjamin F Cravatt; George Kunos
Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase.
American journal of physiology. Heart and circulatory physiology 2005;289(2):H533-41.
2005: Anna Csiszar; Pal Pacher; Gabor Kaley; Zoltan Ungvari
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.
Current vascular pharmacology 2005;3(3):285-91.
2005: Zoltan Ungvári; Sachin A Gupte; Fabio A Recchia; Sándor Bátkai; Pál Pacher
Role of oxidative-nitrosative stress and downstream pathways in various forms of cardiomyopathy and heart failure.
Current vascular pharmacology 2005;3(3):221-9.
2005: Pál Pacher
Dysregulation of nitric oxide (NO).
Current vascular pharmacology 2005;3(3):207.
2005: Pal Pacher; Richard Schulz; Lucas Liaudet; Csaba Szabó
Nitrosative stress and pharmacological modulation of heart failure.
Trends in pharmacological sciences 2005;26(6):302-10.
2005: Pál Pacher; Sándor Bátkai; George Kunos
Blood pressure regulation by endocannabinoids and their receptors.
Neuropharmacology 2005;48(8):1130-8.
2005: György Hajnóczky; Christopher J Buzas; Pál Pacher; Jan B Hoek; Emanuel Rubin
Alcohol and mitochondria in cardiac apoptosis: mechanisms and visualization.
Alcoholism, clinical and experimental research 2005;29(5):693-701.
2005: Malcolm Begg; Pál Pacher; Sándor Bátkai; Douglas Osei-Hyiaman; László Offertáler; Fong Ming Mo; Jie Liu; George Kunos
Evidence for novel cannabinoid receptors.
Pharmacology & therapeutics 2005;106(2):133-45.
2005: Douglas Osei-Hyiaman; Michael DePetrillo; Pál Pacher; Jie Liu; Svetlana Radaeva; Sándor Bátkai; Judith Harvey-White; Ken Mackie; László Offertáler; Lei Wang; et al.
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity.
The Journal of clinical investigation 2005;115(5):1298-305.
2005: B Pesse; S Levrand; F Feihl; B Waeber; B Gavillet; P Pacher; L Liaudet
Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21Ras in H9C2 cardiomyocytes.
Journal of molecular and cellular cardiology 2005;38(5):765-75.
2005: Orsolya Szenczi; Péter Kemecsei; Max F J Holthuijsen; Natal A W van Riel; Ger J van der Vusse; Pál Pacher; Csaba Szabó; Márk Kollai; László Ligeti; Tamás Ivanics
Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure.
Biochemical pharmacology 2005;69(5):725-32.
2005: Jon G Mabley; Pál Pacher; Amitabha Deb; Rebecca Wallace; Rhoderick H Elder; Csaba Szabó
Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):290-2.
2005: P Pacher; S Bátkai; G Kunos
Cardiovascular pharmacology of cannabinoids.
Handbook of experimental pharmacology 2005;(168):599-625.
2005: Pál Pacher; Irina G Obrosova; Jon G Mabley; Csaba Szabó
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.
Current medicinal chemistry 2005;12(3):267-75.
2005: Irina G Obrosova; Pal Pacher; Csaba Szabó; Zsuzsanna Zsengeller; Hiroko Hirooka; Martin J Stevens; Mark A Yorek
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.
Diabetes 2005;54(1):234-42.
2004: Pál Pacher; Jon G Mabley; Lucas Liaudet; Oleg V Evgenov; Anita Marton; György Haskó; Márk Kollai; Csaba Szabó
Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2132-7.
2004: Pál Pacher; Anne Vaslin; Rita Benko; Jon G Mabley; Lucas Liaudet; György Haskó; Anita Marton; Sándor Bátkai; Márk Kollai; Csaba Szabó
A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging.
The Journal of pharmacology and experimental therapeutics 2004;311(2):485-91.
2004: Sándor Bátkai; Pál Pacher; Douglas Osei-Hyiaman; Svetlana Radaeva; Jie Liu; Judith Harvey-White; László Offertáler; Ken Mackie; M Audrey Rudd; Richard D Bukoski; et al.
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Circulation 2004;110(14):1996-2002.
2004: Sándor Bátkai; Pál Pacher; Zoltán Járai; Jens A Wagner; George Kunos
Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors.
American journal of physiology. Heart and circulatory physiology 2004;287(2):H595-600.
2004: Rita Benkö; Pál Pacher; Anne Vaslin; Márk Kollai; Csaba Szabó
Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase.
Life sciences 2004;75(10):1255-61.
2004: Pál Pacher; Sándor Bátkai; George Kunos
Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice.
The Journal of physiology 2004;558(Pt 2):647-57.
2004: George Kunos; Pál Pacher
Cannabinoids cool the intestine.
Nature medicine 2004;10(7):678-9.
2004: Irina G Obrosova; Alexander G Minchenko; Robert N Frank; Gail M Seigel; Zsuzsanna Zsengeller; Pál Pacher; Martin J Stevens; Csaba Szabó
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.
International journal of molecular medicine 2004;14(1):55-64.
2004: Jon G Mabley; Pál Pacher; Peter Bai; Rebecca Wallace; Sunali Goonesekera; Laszlo Virag; Garry J Southan; Csaba Szabó
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways.
Mutation research 2004;548(1-2):107-16.
2004: F Li; C Szabó; P Pacher; G J Southan; O I Abatan; T Charniauskaya; M J Stevens; I G Obrosova
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.
Diabetologia 2004;47(4):710-7.
2004: Pal Pacher; Valeria Kecskemeti
Trends in the development of new antidepressants. Is there a light at the end of the tunnel?
Current medicinal chemistry 2004;11(7):925-43.
2004: Irina G Obrosova; Fei Li; Omorodola I Abatan; Mark A Forsell; Katalin Komjáti; Pal Pacher; Csaba Szabó; Martin J Stevens
Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.
Diabetes 2004;53(3):711-20.
2004: László Virág; Péter Bai; István Bak; Pál Pacher; Jon G Mabley; Lucas Liaudet; Edina Bakondi; Pál Gergely; Márk Kollai; Csaba Szabó
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Medical science monitor : international medical journal of experimental and clinical research 2004;10(3):BR77-83.
2004: Pál Pacher; Valéria Kecskeméti
[Cardiovascular effects of selective serotonin reuptake inhibitor antidepressants].
Orvosi hetilap 2004;145(8):425-31.
2004: Kazunori Murakami; Perenlei Enkhbaatar; Katsumi Shimoda; Robert A Cox; Ann S Burke; Hal K Hawkins; Lillian D Traber; Frank C Schmalstieg; Andrew L Salzman; Jon G Mabley; et al.
Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis.
Shock (Augusta, Ga.) 2004;21(2):126-33.
2004: Péter Bai; Jon G Mabley; Lucas Liaudet; László Virág; Csaba Szabó; Pál Pacher
Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity.
Oncology reports 2004;11(2):505-8.
2004: Csaba Szabó; Pál Pacher; Zsuzsanna Zsengellér; Anne Vaslin; Katalin Komjáti; Rita Benkö; Min Chen; Jon G Mabley; Márk Kollai
Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.
Molecular medicine (Cambridge, Mass.) 2004;10(1-6):28-35.
2004: Pal Pacher; Valeria Kecskemeti
Cardiovascular side effects of new antidepressants and antipsychotics: new drugs, old concerns?
Current pharmaceutical design 2004;10(20):2463-75.
2003: P Pacher; J G Mabley; L Liaudet; O V Evgenov; G J Southan; G E Abdelkarim; C Szabó; A L Salzman
Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats.
International journal of impotence research 2003;15(6):461-4.
2003: Malcolm Begg; Fong-Ming Mo; László Offertaler; Sándor Bátkai; Pál Pacher; Raj K Razdan; David M Lovinger; George Kunos
G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current.
The Journal of biological chemistry 2003;278(46):46188-94.
2003: Jie Liu; Sándor Batkai; Pál Pacher; Judith Harvey-White; Jens A Wagner; Benjamin F Cravatt; Bin Gao; George Kunos
Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor.
The Journal of biological chemistry 2003;278(45):45034-9.
2003: Oleg V Evgenov; Pál Pacher; William Williams; Natalia V Evgenov; Jon G Mabley; James Cicila; Zsombor B Sikó; Andrew L Salzman; Csaba Szabó
Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats.
Critical care medicine 2003;31(10):2429-36.
2003: Alexander G Minchenko; Martin J Stevens; Lauren White; Omorodola I Abatan; Katalin Komjáti; Pal Pacher; Csaba Szabó; Irina G Obrosova
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1514-6.
2003: Edina Bakondi; Mónika Gönczi; Eva Szabó; Péter Bai; Pál Pacher; Pál Gergely; László Kovács; János Hunyadi; Csaba Szabó; László Csernoch; et al.
Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes.
The Journal of investigative dermatology 2003;121(1):88-95.
2003: Jon Mabley; Francisco Soriano; Pál Pacher; György Haskó; Anita Marton; Rebecca Wallace; Andrew Salzman; Csaba Szabó
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis.
European journal of pharmacology 2003;466(3):323-9.
2003: János Magyar; Zoltán Rusznák; Csaba Harasztosi; Agnes Körtvély; Pál Pacher; Tamás Bányász; Csaba Pankucsi; László Kovács; Géza Szûcs; Péter P Nánási; et al.
Differential effects of fluoxetine enantiomers in mammalian neural and cardiac tissues.
International journal of molecular medicine 2003;11(4):535-42.
2003: Jon G Mabley; Alex Rabinovitch; Wilma Suarez-Pinzon; György Haskó; Pál Pacher; Robert Power; Gary Southan; Andrew Salzman; Csaba Szabó
Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.
Molecular medicine (Cambridge, Mass.) 2003;9(3-4):96-104.
2003: Pál Pacher; Lucas Liaudet; Péter Bai; Jon G Mabley; Pawel M Kaminski; László Virág; Amitabha Deb; Eva Szabó; Zoltán Ungvári; Michael S Wolin; et al.
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction.
Circulation 2003;107(6):896-904.
2003: Lucas Liaudet; Csaba Szabó; Oleg V Evgenov; Kanneganti G Murthy; Pál Pacher; László Virág; Jon G Mabley; Anita Marton; Francisco G Soriano; Mikhail Y Kirov; et al.
Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis.
Shock (Augusta, Ga.) 2003;19(2):131-7.
2003: J G Mabley; P Pacher; L Liaudet; F G Soriano; G Haskó; A Marton; C Szabo; A L Salzman
Inosine reduces inflammation and improves survival in a murine model of colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(1):G138-44.
2002: Pál Pacher; Attila Cziráki; Jon G Mabley; Lucas Liaudet; Lajos Papp; Csaba Szabó
Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents.
Biochemical pharmacology 2002;64(12):1785-91.
2002: Mikhail Y Kirov; Oleg V Evgenov; Vladimir N Kuklin; Laszlo Virag; Pal Pacher; Garry J Southan; Andrew L Salzman; Csaba Szabo; Lars J Bjertnaes
Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep.
American journal of respiratory and critical care medicine 2002;166(11):1436-42.
2002: Csaba Szabó; Anne Zanchi; Katalin Komjáti; Pál Pacher; Andrzej S Krolewski; William C Quist; Frank W LoGerfo; Edward S Horton; Aristidis Veves
Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity.
Circulation 2002;106(21):2680-6.
2002: Jon G Mabley; Lucas Liaudet; Pál Pacher; Garry J Southan; John T Groves; Andrew L Salzman; Csaba Szabó
Part II: beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and colitis.
Molecular medicine (Cambridge, Mass.) 2002;8(10):581-90.
2002: Csaba Szabó; Jon G Mabley; Suzanne M Moeller; Roman Shimanovich; Pál Pacher; László Virag; Francisco G Soriano; John H Van Duzer; William Williams; Andrew L Salzman; et al.
Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.
Molecular medicine (Cambridge, Mass.) 2002;8(10):571-80.
2002: János Magyar; Tamás Bányász; Zsolt Bagi; Pál Pacher; Norbert Szentandrássy; László Fülöp; Valéria Kecskeméti; Péter P Nánási
Electrophysiological effects of risperidone in mammalian cardiac cells.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(4):350-6.
2002: Pál Pacher; Lucas Liaudet; Jon g Mabley; Katalin Komjáti; Csaba Szabó
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure.
Journal of the American College of Cardiology 2002;40(5):1006-16.
2002: Zoltán H Németh; Edwin A Deitch; Csaba Szabó; Jon G Mabley; Pál Pacher; Zoltán Fekete; Carl J Hauser; György Haskó
Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G122-32.
2002: Pal Pacher; Jon G Mabley; Francisco G Soriano; Lucas Liaudet; Csaba Szabó
Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging.
International journal of molecular medicine 2002;9(6):659-64.
2002: György Haskó; Jon G Mabley; Zoltán H Németh; Pál Pacher; Edwin A Deitch; Csaba Szabó
Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.
Molecular medicine (Cambridge, Mass.) 2002;8(5):283-9.
2002: A Csiszar; G Stef; P Pacher; Z Ungvari
Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(5-6):557-8.
2002: Pal Pacher; Zoltan Ungvari
Use of selective serotonin reuptake inhibitors and myocardial infarction.
Circulation 2002;105(14):e84.
2002: Francisco Garcia Soriano; Lucas Liaudet; Eva Szabó; László Virág; Jon G Mabley; Pál Pacher; Csaba Szabó
Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice.
Shock (Augusta, Ga.) 2002;17(4):286-92.
2002: Lucas Liaudet; Jon G Mabley; Pál Pacher; László Virág; Francisco G Soriano; Anita Marton; György Haskó; Edwin A Deitch; Csaba Szabó
Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury.
Annals of surgery 2002;235(4):568-78.
2002: Pál Pacher; Jon G Mabley; Francisco G Soriano; Lucas Liaudet; Katalin Komjáti; Csaba Szabó
Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation.
British journal of pharmacology 2002;135(6):1347-50.
2002: J G Mabley; P Pacher; G J Southan; A L Salzman; C Szabó
Nicotine reduces the incidence of type I diabetes in mice.
The Journal of pharmacology and experimental therapeutics 2002;300(3):876-81.
2002: P Pacher; L Liaudet; P Bai; L Virag; J G Mabley; G Haskó; C Szabó
Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure.
The Journal of pharmacology and experimental therapeutics 2002;300(3):862-7.
2002: Pál Pacher; Andrew P Thomas; György Hajnóczky
Ca2+ marks: miniature calcium signals in single mitochondria driven by ryanodine receptors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2380-5.
2002: Lucas Liaudet; Pál Pacher; Jon G Mabley; László Virág; Francisco G Soriano; György Haskó; Csaba Szabó
Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation.
American journal of respiratory and critical care medicine 2002;165(3):372-7.
2002: Pal Pacher; Lucas Liaudet; Francisco Garcia Soriano; Jon G Mabley; Eva Szabó; Csaba Szabó
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes.
Diabetes 2002;51(2):514-21.
2002: Gábor Szabó; Susanne Bährle; Nicole Stumpf; Karin Sonnenberg; Eva Szabó E; Pál Pacher; Tamás Csont; Richard Schulz; Thomas J Dengler; Lucas Liaudet; et al.
Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation.
Circulation research 2002;90(1):100-6.
2002: Z Ungvari; P Pacher; A Csiszar
Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?
Medical hypotheses 2002;58(1):85-6.
2002: Valeria Kecskemeti; Zsolt Bagi; Pal Pacher; Ildiko Posa; Erzsebet Kocsis; Maria Zs Koltai
New trends in the development of oral antidiabetic drugs.
Current medicinal chemistry 2002;9(1):53-71.
2002: Lucas Liaudet; Kanneganti G K Murthy; Jon G Mabley; Pál Pacher; Francisco G Soriano; Andrew L Salzman; Csaba Szabó
Comparison of inflammation, organ damage, and oxidant stress induced by Salmonella enterica serovar Muenchen flagellin and serovar Enteritidis lipopolysaccharide.
Infection and immunity 2002;70(1):192-8.
2001: A Marton; P Pacher; K G Murthy; Z H Németh; G Haskó; C Szabó
Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.
International journal of molecular medicine 2001;8(6):617-21.
2001: F G Soriano; P Pacher; J Mabley; L Liaudet; C Szabó
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase.
Circulation research 2001;89(8):684-91.
2001: L Liaudet; J G Mabley; F G Soriano; P Pacher; A Marton; G Haskó; C Szabó
Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture.
American journal of respiratory and critical care medicine 2001;164(7):1213-20.
2001: P Pacher; Z Ungvari
Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels.
Medical hypotheses 2001;57(4):469-71.
2001: G Hajnóczky; P Pacher; X Lin
Spatio-temporal organization of the mitochondrial phase of apoptosis.
IUBMB life 2001;52(3-5):237-45.
2001: P Pacher; G Hajnóczky
Propagation of the apoptotic signal by mitochondrial waves.
The EMBO journal 2001;20(15):4107-21.
2001: P Pacher; Z Ungvari; V Kecskeméti; T Friedmann; S Furst
Serotonin reuptake inhibitors fluoxetine and citalopram relax intestinal smooth muscle.
Canadian journal of physiology and pharmacology 2001;79(7):580-4.
2001: P Pacher; G Csordás; G Hajnóczky
Mitochondrial ca(2+) signaling and cardiac apoptosis.
Biological signals and receptors 2001;10(3-4):200-23.
2001: P Pacher; E Kohegyi; V Kecskemeti; S Furst
Current trends in the development of new antidepressants.
Current medicinal chemistry 2001;8(2):89-100.
2000: P Pacher; P Csordás; T Schneider; G Hajnóczky
Quantification of calcium signal transmission from sarco-endoplasmic reticulum to the mitochondria.
The Journal of physiology 2000;529 Pt 3():553-64.
2000: G Hajnóczky; G Csordás; M Madesh; P Pacher
The machinery of local Ca2+ signalling between sarco-endoplasmic reticulum and mitochondria.
The Journal of physiology 2000;529 Pt 1():69-81.
2000: G Hajnóczky; G Csordás; M Madesh; P Pacher
Control of apoptosis by IP(3) and ryanodine receptor driven calcium signals.
Cell calcium 2000;28(5-6):349-63.
2000: E Kocsis; P Pacher; I Pósa; E Nieszner; G Pogátsa; M Z Koltai
Hyperglycaemia alters the endothelium-dependent relaxation of canine coronary arteries.
Acta physiologica Scandinavica 2000;169(3):183-7.
2000: Z Ungvari; P Pacher; A Koller
Serotonin reuptake inhibitor fluoxetine decreases arteriolar myogenic tone by reducing smooth muscle [Ca2+]i.
Journal of cardiovascular pharmacology 2000;35(6):849-54.
2000: F Deák; B Lasztóczi; P Pacher; G L Petheö; Valéria Kecskeméti; A Spät
Inhibition of voltage-gated calcium channels by fluoxetine in rat hippocampal pyramidal cells.
Neuropharmacology 2000;39(6):1029-36.
2000: P Pacher; Z Bagi; Z Lakó-Futó; Z Ungvári; P P Nánási; V Kecskeméti
Cardiac electrophysiological effects of citalopram in guinea pig papillary muscle comparison with clomipramine.
General pharmacology 2000;34(1):17-23.
2000: P Pacher; J Magyar; P Szigligeti; T Bányász; C Pankucsi; Z Korom; Z Ungvári; V Kecskeméti; P P Nánási
Electrophysiological effects of fluoxetine in mammalian cardiac tissues.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(1):67-73.
1999: Z Ungvari; P Pacher; V Kecskemeti; G Papp; L Szollár; A Koller
Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C.
Cardiovascular research 1999;43(4):1018-28.
1999: Z Ungvari; P Pacher; V Kecskeméti; A Koller
Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener.
Stroke; a journal of cerebral circulation 1999;30(9):1949-54.
1999: Z Ungvari; P Pacher; K Rischák; L Szollár; A Koller
Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(8):1899-904.
1999: P Pacher; Z Ungvari; V Kecskemeti; A Koller
Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity.
British journal of pharmacology 1999;127(3):740-6.
1999: P Pacher; Z Ungvari; P P Nanasi; S Furst; V Kecskemeti
Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any?
Current medicinal chemistry 1999;6(6):469-80.
1999: P Pacher; Z Ungvári; P P Nánási; V Kecskeméti
Electrophysiological changes in rat ventricular and atrial myocardium at different stages of experimental diabetes.
Acta physiologica Scandinavica 1999;166(1):7-13.
1999: P Pacher; Z Ungvári; P P Nánási; I Mucha; V Kecskeméti; G Losonczy
Post-partum prolongation of the atrial repolarization in rabbit.
Acta physiologica Scandinavica 1999;166(1):1-5.
1999: P Pacher; Z Ungvari; V Kecskemeti
Electrophysiological effects of homocysteine in isolated rat right ventricular papillary muscles and left atria.
General pharmacology 1999;32(4):439-43.
1998: P Pacher; Z Ungvari; V Kecskemeti; S Furst
Review of cardiovascular effects of fluoxetine, a selective serotonin reuptake inhibitor, compared to tricyclic antidepressants.
Current medicinal chemistry 1998;5(5):381-90.
1998: P Pacher; V Kecskemeti; A Z Ronai; I Balogh; G Szalai; B Matkovics
Changes in cardiac electrophysiology, morphology, tissue biochemistry and vascular reactions in glutathione depleted animals.
Molecular and cellular biochemistry 1998;185(1-2):183-90.
1996: V Kecskemeti; P Pacher; C Pankucsi; P Nanasi
Comparative study of cardiac electrophysiological effects of atrial natriuretic peptide.
Molecular and cellular biochemistry 1996;160-161():53-9.
1996: P Pacher; V Kecskeméti; R Felkai; T Tószegi; B Matkovics; M Paróczai
Effect of glutathione depletion on electrophysiological characteristics of guinea-pig ventricles.
Acta physiologica Hungarica 1996;84(3):319-21.
1996: V Kecskeméti; P Pacher; G Szalai; I Wollak; K Tekes; I Posa; E Kocsis
Electrophysiological characteristics of ventricular muscles from diabetic hearts.
Acta physiologica Hungarica 1996;84(3):295-6.