Philip E. auron

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Mahony Shaun; Auron Philip E; Benos Panayiotis V
Inferring protein-DNA dependencies using motif alignments and mutual information.
Unlu Sebnem; Kumar Arvind; Waterman Wayne R; Tsukada Junichi; Wang Kent Z Q; Galson Deborah L; Auron Philip E
Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene.
Yang Jinbo; Liao Xudong; Agarwal Mukesh K; Barnes Laura; Auron Philip E; Stark George R
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB.

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2007: Mahony Shaun; Auron Philip E; Benos Panayiotis V
Inferring protein-DNA dependencies using motif alignments and mutual information.
Bioinformatics (Oxford, England) 2007;23(13):i297-304.
2007: Unlu Sebnem; Kumar Arvind; Waterman Wayne R; Tsukada Junichi; Wang Kent Z Q; Galson Deborah L; Auron Philip E
Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene.
Molecular immunology 2007;44(13):3364-79.
2007: Yang Jinbo; Liao Xudong; Agarwal Mukesh K; Barnes Laura; Auron Philip E; Stark George R
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB.
Genes & development 2007;21(11):1396-408.
2007: Auron Philip E; Webb Andrew C; Rosenwasser Lanny J; Mucci Steven F; Rich Alexander; Wolff Sheldon M; Dinarello Charles A
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5413-7.
2007: Mahony Shaun; Auron Philip E; Benos Panayiotis V
DNA familial binding profiles made easy: comparison of various motif alignment and clustering strategies.
PLoS computational biology 2007;3(3):e61.
2006: Wang Kent Z Q; Wara-Aswapati Nawarat; Boch Jason A; Yoshida Yasuhiro; Hu Chang-Deng; Galson Deborah L; Auron Philip E
TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.
Journal of cell science 2006;119(Pt 8):1579-91.
2006: Waterman Wayne R; Xu Li Lian; Tetradis Sotirios; Motyckova Gabriela; Tsukada Junichi; Saito Kazuyoshi; Webb Andrew C; Robinson Dwight R; Auron Philip E
Glucocorticoid inhibits the human pro-interleukin lbeta gene (ILIB) by decreasing DNA binding of transactivators to the signal-responsive enhancer.
Molecular immunology 2006;43(7):773-82.
2005: Listman James A; Wara-aswapati Nawarat; Race JoAnne E; Blystone Lisa W; Walker-Kopp Nancy; Yang Zhiyong; Auron Philip E
Conserved ETS domain arginines mediate DNA binding, nuclear localization, and a novel mode of bZIP interaction.
The Journal of biological chemistry 2005;280(50):41421-8.
2004: Yoshida Yasuhiro; Kumar Arvind; Koyama Yoshinobu; Peng Haibing; Arman Ahmet; Boch Jason A; Auron Philip E
Interleukin 1 activates STAT3/nuclear factor-kappaB cross-talk via a unique TRAF6- and p65-dependent mechanism.
The Journal of biological chemistry 2004;279(3):1768-76.
2003: Tan Lujian; Peng Haibing; Osaki Makoto; Choy Bob K; Auron Philip E; Sandell Linda J; Goldring Mary B
Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta.
The Journal of biological chemistry 2003;278(20):17688-700.
2003: Boch Jason A; Yoshida Yasuhiro; Koyama Yoshinobu; Wara-Aswapati Nawarat; Peng Hiabing; Unlu Sebnem; Auron Philip E
Characterization of a cascade of protein interactions initiated at the IL-1 receptor.
Biochemical and biophysical research communications 2003;303(2):525-31.
2003: Wara-Aswapati N; Boch J A; Auron P E
Activation of interleukin 1beta gene transcription by human cytomegalovirus: molecular mechanisms and relevance to periodontitis.
Oral microbiology and immunology 2003;18(2):67-71.
2003: Osaki Makoto; Tan Lujian; Choy Bob K; Yoshida Yasuhiro; Cheah Kathryn S E; Auron Philip E; Goldring Mary B
The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2.
The Biochemical journal 2003;369(Pt 1):103-15.
2003: Arman Ahmet; Auron Philip E
Interleukin 1 (IL-1) induces the activation of Stat3.
Advances in experimental medicine and biology 2003;534():297-307.
2002: Yang Zhiyong; Wara-aswapati Nawarat; Yoshida Yasuhiro; Walker Nancy; Galson Deborah L; Listman James; Auron Philip E
Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1.
Biochemical and biophysical research communications 2002;294(4):854-63.
2002: Silverman Eric S; Le Louis; Baron Rebecca M; Hallock Arlene; Hjoberg Josephine; Shikanai Toshiki; Storm van's Gravesande Karin; Auron Philip E; Lu Weining
Cloning and functional analysis of the mouse 5-lipoxygenase promoter.
American journal of respiratory cell and molecular biology 2002;26(4):475-83.
2002: Asea Alexzander; Rehli Michael; Kabingu Edith; Boch Jason A; Bare Olivia; Auron Philip E; Stevenson Mary Ann; Calderwood Stuart K
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.
The Journal of biological chemistry 2002;277(17):15028-34.
2002: Xie Yue; Chen Changmin; Stevenson Mary Ann; Auron Philip E; Calderwood Stuart K
Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6.
The Journal of biological chemistry 2002;277(14):11802-10.
2002: Xie Yue; Chen Changmin; Stevenson Mary Ann; Hume David A; Auron Philip E; Calderwood Stuart K
NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells.
Biochemical and biophysical research communications 2002;291(4):1071-80.
2002: Toda Yoko; Tsukada Junichi; Misago Masahiro; Kominato Yoshihiko; Auron Philip E; Tanaka Yoshiya
Autocrine induction of the human pro-IL-1beta gene promoter by IL-1beta in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1984-91.
2001: Riquet F B; Tan L; Choy B K; Osaki M; Karsenty G; Osborne T F; Auron P E; Goldring M B
YY1 is a positive regulator of transcription of the Col1a1 gene.
The Journal of biological chemistry 2001;276(42):38665-72.
2001: Boch J A; Wara-aswapati N; Auron P E
Interleukin 1 signal transduction--current concepts and relevance to periodontitis.
Journal of dental research 2001;80(2):400-7.
2001: Gravallese E M; Galson D L; Goldring S R; Auron P E
The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption.
Arthritis research 2001;3(1):6-12.
2000: Yang Z; Wara-Aswapati N; Chen C; Tsukada J; Auron P E
NF-IL6 (C/EBPbeta ) vigorously activates il1b gene expression via a Spi-1 (PU.1) protein-protein tether.
The Journal of biological chemistry 2000;275(28):21272-7.
2000: Tsukada J; Toda Y; Misago M; Tanaka Y; Auron P E; Eto S
Constitutive activation of LIL-Stat in adult T-cell leukemia cells.
Blood 2000;95(8):2715-8.
1999: Wara-aswapati N; Yang Z; Waterman W R; Koyama Y; Tetradis S; Choy B K; Webb A C; Auron P E
Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1.
Molecular and cellular biology 1999;19(10):6803-14.
1999: Zhang P; Behre G; Pan J; Iwama A; Wara-Aswapati N; Radomska H S; Auron P E; Tenen D G; Sun Z
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8705-10.
1999: Bavelloni A; Santi S; Sirri A; Riccio M; Faenza I; Zini N; Cecchi S; Ferri A; Auron P; Maraldi N M; Marmiroli S
Phosphatidylinositol 3-kinase translocation to the nucleus is induced by interleukin 1 and prevented by mutation of interleukin 1 receptor in human osteosarcoma Saos-2 cells.
Journal of cell science 1999;112 ( Pt 5)():631-40.
1999: Xie Y; Cahill C M; Asea A; Auron P E; Calderwood S K
Heat shock proteins and regulation of cytokine expression.
Infectious diseases in obstetrics and gynecology 1999;7(1-2):26-30.
1998: Marmiroli S; Bavelloni A; Faenza I; Sirri A; Ognibene A; Cenni V; Tsukada J; Koyama Y; Ruzzene M; Ferri A; Auron P E; Toker A; Maraldi N M
Phosphatidylinositol 3-kinase is recruited to a specific site in the activated IL-1 receptor I.
FEBS letters 1998;438(1-2):49-54.
1998: Auron P E
The interleukin 1 receptor: ligand interactions and signal transduction.
Cytokine & growth factor reviews 1998;9(3-4):221-37.
1997: Tsukada J; Misago M; Serino Y; Ogawa R; Murakami S; Nakanishi M; Tonai S; Kominato Y; Morimoto I; Auron P E; Eto S
Human T-cell leukemia virus type I Tax transactivates the promoter of human prointerleukin-1beta gene through association with two transcription factors, nuclear factor-interleukin-6 and Spi-1.
Blood 1997;90(8):3142-53.
1997: Chen C; Xie Y; Stevenson M A; Auron P E; Calderwood S K
Heat shock factor 1 represses Ras-induced transcriptional activation of the c-fos gene.
The Journal of biological chemistry 1997;272(43):26803-6.
1996: Koyama Y; Tanaka Y; Saito K; Abe M; Nakatsuka K; Morimoto I; Auron P E; Eto S
Cross-linking of intercellular adhesion molecule 1 (CD54) induces AP-1 activation and IL-1beta transcription.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):5097-103.
1996: Cahill C M; Waterman W R; Xie Y; Auron P E; Calderwood S K
Transcriptional repression of the prointerleukin 1beta gene by heat shock factor 1.
The Journal of biological chemistry 1996;271(40):24874-9.
1996: Tsukada J; Waterman W R; Koyama Y; Webb A C; Auron P E
A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene.
Molecular and cellular biology 1996;16(5):2183-94.
1996: Robinson D R; Urakaze M; Huang R; Taki H; Sugiyama E; Knoell C T; Xu L; Yeh E T; Auron P E
Dietary marine lipids suppress continuous expression of interleukin-1 beta gene transcription.
Lipids 1996;31 Suppl():S23-31.
1996: Sun Z; Yergeau D A; Wong I C; Tuypens T; Tavernier J; Paul C C; Baumann M A; Auron P E; Tenen D G; Ackerman S J
Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element that acts lie an enhancer in regulating activity of the IL-5R alpha promoter.
Current topics in microbiology and immunology 1996;211():173-87.
1995: Kominato Y; Galson D; Waterman W R; Webb A C; Auron P E
Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1.
Molecular and cellular biology 1995;15(1):58-68.
1994: Tsukada J; Saito K; Waterman W R; Webb A C; Auron P E
Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.
Molecular and cellular biology 1994;14(11):7285-97.
1994: Auron P E; Webb A C
Interleukin-1: a gene expression system regulated at multiple levels.
European cytokine network 1994;5(6):573-92.
1994: Robinson D R; Xu L L; Knoell C T; Tateno S; Guo M; Colvin R B; Olesiak W; Urakaze M; Sugiyama E; Auron P E
Alleviation of autoimmune disease by omega 3 fatty acids.
World review of nutrition and dietetics 1994;76():95-102.
1993: Galson D L; Hensold J O; Bishop T R; Schalling M; D'Andrea A D; Jones C; Auron P E; Housman D E
Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.
Molecular and cellular biology 1993;13(5):2929-41.
1993: Shirakawa F; Saito K; Bonagura C A; Galson D L; Fenton M J; Webb A C; Auron P E
The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction.
Molecular and cellular biology 1993;13(3):1332-44.
1992: Gorn A H; Lin H Y; Yamin M; Auron P E; Flannery M R; Tapp D R; Manning C A; Lodish H F; Krane S M; Goldring S R
Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line.
The Journal of clinical investigation 1992;90(5):1726-35.
1992: Hunninghake G W; Monks B G; Geist L J; Monick M M; Monroy M A; Stinski M F; Webb A C; Dayer J M; Auron P E; Fenton M J
The functional importance of a cap site-proximal region of the human prointerleukin 1 beta gene is defined by viral protein trans-activation.
Molecular and cellular biology 1992;12(8):3439-48.
1992: Auron P E; Quigley G J; Rosenwasser L J; Gehrke L
Multiple amino acid substitutions suggest a structural basis for the separation of biological activity and receptor binding in a mutant interleukin-1 beta protein.
Biochemistry 1992;31(29):6632-8.
1992: Crump J W; Geist L J; Auron P E; Webb A C; Stinski M F; Hunninghake G W
The immediate early genes of human cytomegalovirus require only proximal promoter elements to upregulate expression of interleukin-1 beta.
American journal of respiratory cell and molecular biology 1992;6(6):674-7.
1991: Conca W; Auron P E; Aoun-Wathne M; Bennett N; Seckinger P; Welgus H G; Goldring S R; Eisenberg S P; Dayer J M; Krane S M
An interleukin 1 beta point mutant demonstrates that jun/fos expression is not sufficient for fibroblast metalloproteinase expression.
The Journal of biological chemistry 1991;266(25):16265-8.
1990: Rogers J T; Bridges K R; Durmowicz G P; Glass J; Auron P E; Munro H N
Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1.
The Journal of biological chemistry 1990;265(24):14572-8.
1990: Iwamoto G K; Monick M M; Clark B D; Auron P E; Stinski M F; Hunninghake G W
Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus.
The Journal of clinical investigation 1990;85(6):1853-7.
1990: Gehrke L; Jobling S A; Paik L S; McDonald B; Rosenwasser L J; Auron P E
A point mutation uncouples human interleukin-1 beta biological activity and receptor binding.
The Journal of biological chemistry 1990;265(11):5922-5.
1990: Samia J A; Alexander S J; Horton K W; Auron P E; Byers M G; Shows T B; Webb A C
Chromosomal organization and localization of the human urokinase inhibitor gene: perfect structural conservation with ovalbumin.
Genomics 1990;6(1):159-67.
1989: Dudding L; Haskill S; Clark B D; Auron P E; Sporn S; Huang E S
Cytomegalovirus infection stimulates expression of monocyte-associated mediator genes.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(10):3343-52.
1988: Jobling S A; Auron P E; Gurka G; Webb A C; McDonald B; Rosenwasser L J; Gehrke L
Biological activity and receptor binding of human prointerleukin-1 beta and subpeptides.
The Journal of biological chemistry 1988;263(31):16372-8.
1988: Auron P E; Sullivan D; Fenton M J; Clark B D; Cole E S; Galson D L; Peters L; Teller D
The Nucleic Acid Blot Analyzer II. ANALYZE, an image analysis software package for molecular biology.
BioTechniques 1988;6(4):347-53.
1988: Fenton M J; Vermeulen M W; Clark B D; Webb A C; Auron P E
Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2267-73.
1987: Webb A C; Collins K L; Snyder S E; Alexander S J; Rosenwasser L J; Eddy R L; Shows T B; Auron P E
Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment, and homology to plasminogen activator-inhibitor.
The Journal of experimental medicine 1987;166(1):77-94.
1987: Fenton M J; Clark B D; Collins K L; Webb A C; Rich A; Auron P E
Transcriptional regulation of the human prointerleukin 1 beta gene.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(11):3972-9.
1987: Auron P E; Webb A C
The structure and regulation of the human prointerleukin-1 beta gene.
Annales de l'Institut Pasteur. Immunology 1987;138(3):462-9.
1987: Auron P E; Warner S J; Webb A C; Cannon J G; Bernheim H A; McAdam K J; Rosenwasser L J; LoPreste G; Mucci S F; Dinarello C A
Studies on the molecular nature of human interleukin 1.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(5):1447-56.
1986: Clark B D; Collins K L; Gandy M S; Webb A C; Auron P E
Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene.
Nucleic acids research 1986;14(20):7897-914.
1986: Rosenwasser L J; Webb A C; Clark B D; Irie S; Chang L; Dinarello C A; Gehrke L; Wolff S M; Rich A; Auron P E
Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(14):5243-6.
1986: Dinarello C A; Cannon J G; Mier J W; Bernheim H A; LoPreste G; Lynn D L; Love R N; Webb A C; Auron P E; Reuben R C
Multiple biological activities of human recombinant interleukin 1.
The Journal of clinical investigation 1986;77(6):1734-9.
1986: Wolff S M; Auron P E; Dinarello C A; Rosenwasser L J; Webb A C; Rich A
Clone controversy at Immunex.
Nature 1986;319(6051):270.
1986: Webb A C; Collins K L; Auron P E; Eddy R L; Nakai H; Byers M G; Haley L L; Henry W M; Shows T B
Interleukin-1 gene (IL1) assigned to long arm of human chromosome 2.
Lymphokine research 1986;5(2):77-85.
1985: Auron P E; Rosenwasser L J; Matsushima K; Copeland T; Dinarello C A; Oppenheim J J; Webb A C
Human and murine interleukin 1 possess sequence and structural similarities.
The Journal of molecular and cellular immunology : JMCI 1985;2(3):169-77.
1984: Auron P E; Webb A C; Rosenwasser L J; Mucci S F; Rich A; Wolff S M; Dinarello C A
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7907-11.
1984: Quigley G J; Gehrke L; Roth D A; Auron P E
Computer-aided nucleic acid secondary structure modeling incorporating enzymatic digestion data.
Nucleic acids research 1984;12(1 Pt 1):347-66.
1983: Gehrke L; Auron P E; Quigley G J; Rich A; Sonenberg N
5'-Conformation of capped alfalfa mosaic virus ribonucleic acid 4 may reflect its independence of the cap structure or of cap-binding protein for efficient translation.
Biochemistry 1983;22(22):5157-64.
1982: Auron P E; Weber L D; Rich A
Comparison of transfer ribonucleic acid structures using cobra venom and S1 endonucleases.
Biochemistry 1982;21(19):4700-6.
1982: Auron P E; Rindone W P; Vary C P; Celentano J J; Vournakis J N
Computer-aided prediction of RNA secondary structures.
Nucleic acids research 1982;10(1):403-19.
1981: Auron P E; Fahnestock S R
Functional organization of the large ribosomal subunit of Bacillus stearothermophilus.
The Journal of biological chemistry 1981;256(19):10105-10.

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