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Shimon Lecht

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Jennifer L Strande; Shimon Lecht; Kasi V Routhu; Philip Lazarovici
Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.
Keren Ettinger; Shlomit Aga-Mizrachi; Hadar Arien-Zakay; Gadi Cohen; Shimon Lecht; Cezary Marcinkiewicz; Hinyu Nedev; Yoram Nevo; H Uri Saragovi; Nurit Yanay; Philip Lazarovici
Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model.
Shimon Lecht; Peter I Lelkes; Henry Matzner; Elena Rotfeld; Rinat Tabakman; Rami Yaka; Hadar Arien-Zakay; Philip Lazarovici
Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.

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All Publications

2013: Jennifer L Strande; Shimon Lecht; Kasi V Routhu; Philip Lazarovici
Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.
Journal of basic and clinical physiology and pharmacology 2013;24(1):81-4.
2012: Keren Ettinger; Shlomit Aga-Mizrachi; Hadar Arien-Zakay; Gadi Cohen; Shimon Lecht; Cezary Marcinkiewicz; Hinyu Nedev; Yoram Nevo; H Uri Saragovi; Nurit Yanay; Philip Lazarovici
Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model.
Cellular signalling 2012;24(12):2378-88.
2012: Shimon Lecht; Peter I Lelkes; Henry Matzner; Elena Rotfeld; Rinat Tabakman; Rami Yaka; Hadar Arien-Zakay; Philip Lazarovici
Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2012;30(6):465-9.
2012: Gadi Cohen; Keren Ettinger; Orit Amsalem; Hadar Arien-Zakay; Simon Benita; Shimon Lecht; Aviram Nissan; Mor Oron-Herman; Diana Prus; Eylon Yavin; Philip Lazarovici
Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.
PloS one 2012;7(11):e48803.
2011: Dan Deutsch; Philip Lazarovici; Shimon Lecht; Dekel Shilo; Nechama Silverstein; Anat Blumenfeld
Biphasic influence of hypoxia on tuftelin expression in mouse mesenchymal C3H10T1/2 stem cells.
European journal of oral sciences 2011;119 Suppl 1():55-61.
2011: Emma Portnoy; Dganit Danino; Philip Lazarovici; Shimon Lecht; Shlomo Magdassi
Cetuximab-labeled liposomes containing near-infrared probe for in vivo imaging.
Nanomedicine : nanotechnology, biology, and medicine 2011;7(4):480-8.
2011: Hadar Arien-Zakay; Shimon Lecht; Armon Nagler; Philip Lazarovici
Neuroprotection by human umbilical cord blood-derived progenitors in ischemic brain injuries.
Archives italiennes de biologie 2011;149(2):233-45.
2011: Taher Nassar; Suha Attili-Qadri; Oshrat Harush-Frenkel; Shimon Farber; Shimon Lecht; Philip Lazarovici; Simon Benita
High plasma levels and effective lymphatic uptake of docetaxel in an orally available nanotransporter formulation.
Cancer research 2011;71(8):3018-28.
2011: Yoav Leiser; Nechama Silverstein; Anat Blumenfeld; Dekel Shilo; Amir Haze; Eli Rosenfeld; Boaz Shay; Rinat Tabakman; Shimon Lecht; Philip Lazarovici; Dan Deutsch
The induction of tuftelin expression in PC12 cell line during hypoxia and NGF-induced differentiation.
Journal of cellular physiology 2011;226(1):165-72.
2010: Yoram Finkelstein; Dejan Milatovic; Philip Lazarovici; Amit Ophir; Elihu D Richter; Michael Aschner; Shimon Lecht; Cezary Marcinkiewicz; Peter Lelkes; Snjezana Zaja-Milatovic; Ramesh C Gupta; Berta Brodsky; Avigail Rosengarten; Elena Proscura; Elena Shapira; Uri Wormser
Peaceful use of disastrous neurotoxicants.
Neurotoxicology 2010;31(5):608-20.
2010: Shimon Lecht; Hadar Arien-Zakay; Yoav Wagenstein; Seiji Inoue; Cezary Marcinkiewicz; Peter Lelkes; Philip Lazarovici
Transient signaling of Erk1/2, Akt and PLCgamma induced by nerve growth factor in brain capillary endothelial cells.
Vascular pharmacology 2010;53(3-4):107-14.
2010: Shimon Lecht; Hadar Arien-Zakay; Martin Kohan; Peter Lelkes; Philip Lazarovici
Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells.
Molecular and cellular biochemistry 2010;339(1-2):201-13.
2010: Shimon Lecht; Carola Foerster; Hadar Arien-Zakay; Cezary Marcinkiewicz; Philip Lazarovici; Peter Lelkes
Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2.
In vitro cellular & developmental biology. Animal 2010;46(5):469-76.
2010: Shimon Lecht; Hadar Arien-Zakay; Cezary Marcinkiewicz; Peter Lelkes; Philip Lazarovici
Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation.
Journal of molecular neuroscience : MN 2010;41(1):183-92.
2010: Lina Krasny; Nilly Shimony; Keren Tzukert; Raphael Gorodetsky; Shimon Lecht; Dirk M Nettelbeck; Yosef S Haviv
An in-vitro tumour microenvironment model using adhesion to type I collagen reveals Akt-dependent radiation resistance in renal cancer cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(2):373-80.
2010: Hadar Arien-Zakay; Shimon Lecht; Arnon Nagler; Philip Lazarovici
Human umbilical cord blood stem cells: rational for use as a neuroprotectant in ischemic brain disease.
International journal of molecular sciences 2010;11(9):3513-28.
2009: Hadar Arien-Zakay; Shimon Lecht; M M Bercu; Ninette Amariglio; Gideon Rechavi; Hanan Galski; Philip Lazarovici; Arnon Nagler
Interferon-gamma-induced neuronal differentiation of human umbilical cord blood-derived progenitors.
Leukemia 2009;23(10):1790-800.
2009: Hadar Arien-Zakay; Shimon Lecht; Marian M Bercu; Rinat Tabakman; Ron Kohen; Hanan Galski; Arnon Nagler; Philip Lazarovici
Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors.
Experimental neurology 2009;216(1):83-94.
2009: Hadar Arien-Zakay; Shimon Lecht; Anat Perets; Blair Roszell; Peter Lelkes; Philip Lazarovici
Quantitative assessment of neuronal differentiation in three-dimensional collagen gels using enhanced green fluorescence protein expressing PC12 pheochromocytoma cells.
Journal of molecular neuroscience : MN 2009;37(3):225-37.
2009: Simon Haroutiunian; Shimon Lecht; Arik A Zur; Amnon Hoffman; Elyad M Davidson
The challenge of pain management in patients with myasthenia gravis.
Journal of pain & palliative care pharmacotherapy 2009;23(3):242-60.
2008: Israel Ringel; Shimon Lecht; Marina Sterin; Peter Lelkes; Philip Lazarovici
31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel constructs as an enabling platform technology: II. The effect of anti-inflammatory drugs on phosphometabolite levels.
Endothelium : journal of endothelial cell research 2008;15(5-6):299-307.
2008: Marina Sterin; Israel Ringel; Shimon Lecht; Peter Lelkes; Philip Lazarovici
31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: I. The effect of glial cells and valproic acid on phosphometabolite levels.
Endothelium : journal of endothelial cell research 2008;15(5-6):288-98.
2008: Sofiya Kolusheva; Shimon Lecht; Yael Derazon; Raz Jelinek; Philip Lazarovici
Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane assay.
Peptides 2008;29(9):1620-5.
2008: Mogher Khamaisi; Itamar Raz; V Shilo; Ahuva Shina; Christian Rosenberger; R Dahan; Zaid Abassi; Rina Meidan; Shimon Lecht; Samuel N Heyman
Diabetes and radiocontrast media increase endothelin converting enzyme-1 in the kidney.
Kidney international 2008;74(1):91-100.
2008: Izabela Staniszewska; Ilker K Sariyer; Shimon Lecht; Meghan C Brown; Erin M Walsh; George P Tuszynski; Mahmut Safak; Philip Lazarovici; Cezary Marcinkiewicz
Integrin alpha9 beta1 is a receptor for nerve growth factor and other neurotrophins.
Journal of cell science 2008;121(Pt 4):504-13.
2007: Shimon Lecht; Simon Haroutiunian; Amnon Hoffman; Philip Lazarovici
Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy.
Therapeutics and clinical risk management 2007;3(3):467-74.
2004: Rinat Tabakman; Shimon Lecht; Stela Sephanova; Hadar Arien-Zakay; Philip Lazarovici
Interactions between the cells of the immune and nervous system: neurotrophins as neuroprotection mediators in CNS injury.
Progress in brain research 2004;146():387-401.
2004: Rinat Tabakman; Shimon Lecht; Philip Lazarovici
Neuroprotection by monoamine oxidase B inhibitors: a therapeutic strategy for Parkinson's disease?
BioEssays : news and reviews in molecular, cellular and developmental biology 2004;26(1):80-90.
2001: Alexander M Ponizovsky; Ilan Modai; Yakov Nechamkin; Gregory Barshtein; Michael Ritsner; S Yedgar; Shimon Lecht; Lev D Bergelson
Phospholipid patterns of erythrocytes in schizophrenia: relationships to symptomatology.
Schizophrenia research 2001;52(1-2):121-6.