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Qiongman Kong

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Chien-liang Glenn Lin; Qiongman Kong; Gregory D Cuny; Marcie A Glicksman
Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases.
Qiongman Kong; Sarah Carothers; Yueming Chang; Chien-Liang Glenn Lin
The importance of preclinical trial timing - a potential reason for the disconnect between mouse studies and human clinical trials in ALS.
Qiongman Kong; Yuchen Lin; Delanie Schulte; Nathan Stouffer; Kou Takahashi; Chien-liang Glenn Lin
Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus.

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All Publications

2012: Chien-liang Glenn Lin; Qiongman Kong; Gregory D Cuny; Marcie A Glicksman
Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases.
Future medicinal chemistry 2012;4(13):1689-700.
2012: Qiongman Kong; Sarah Carothers; Yueming Chang; Chien-Liang Glenn Lin
The importance of preclinical trial timing - a potential reason for the disconnect between mouse studies and human clinical trials in ALS.
CNS neuroscience & therapeutics 2012;18(9):791-3.
2012: Qiongman Kong; Yuchen Lin; Delanie Schulte; Nathan Stouffer; Kou Takahashi; Chien-liang Glenn Lin
Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus.
Neurobiology of disease 2012;47(2):145-54.
2011: Xuechao Xing; Ling-Chu Chang; Craig K Colton; Marcie A Glicksman; Qiongman Kong; Liching Lai; Chien-liang Glenn Lin; Gregory D Cuny
Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.
Bioorganic & medicinal chemistry letters 2011;21(19):5774-7.
2010: Craig K Colton; Qiongman Kong; Liching Lai; Michael X Zhu; Kathleen I Seyb; Gregory D Cuny; Jun Xian; Marcie A Glicksman; Chien-Liang Glenn Lin
Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.
Journal of biomolecular screening 2010;15(6):653-62.
2010: Qiongman Kong; Chien-liang Glenn Lin
Oxidative damage to RNA: mechanisms, consequences, and diseases.
Cellular and molecular life sciences : CMLS 2010;67(11):1817-29.
2010: Guilian Tian; Qiongman Kong; Liching Lai; Abhik Ray-Chaudhury; Chien-liang G Lin
Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease.
Journal of neurochemistry 2010;113(4):978-89.
2009: Qiongman Kong; Troy S Peterson; Olga Baker; Emily Stanley; Jean M Camden; Cheikh I Seye; Laurie Erb; Agnes Simonyi; W Gibson Wood; Grace Y Sun; Gary A Weisman
Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor.
Journal of neurochemistry 2009;109(5):1300-10.
2008: Qiongman Kong; Xiu Shan; Yueming Chang; Hirofumi Tashiro; Chien-liang Glenn Lin
RNA oxidation: a contributing factor or an epiphenomenon in the process of neurodegeneration.
Free radical research 2008;42(9):773-7.
2008: Qiongman Kong; Michael P Stockinger; Yueming Chang; Hirofumi Tashiro; Chien-liang Glenn Lin
The presence of rRNA sequences in polyadenylated RNA and its potential functions.
Biotechnology journal 2008;3(8):1041-6.
2008: Yueming Chang; Qiongman Kong; Xiu Shan; Guilian Tian; Hristelina Ilieva; Don W Cleveland; Jeffrey rothstein; David R Borchelt; Philip C Wong; Chien-liang Glenn Lin
Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.
PloS one 2008;3(8):e2849.
2007: Cheikh I Seye; Qiongman Kong; Ningpu Yu; Fernando A Gonzalez; Laurie Erb; Gary A Weisman
P2 receptors in atherosclerosis and postangioplasty restenosis.
Purinergic signalling 2007;3(1-2):153-62.
2006: Cheikh I Seye; Qiongman Kong; Ningpu Yu; Fernando A Gonzalez; Laurie Erb; Gary A Weisman
P2 receptors in atherosclerosis and postangioplasty restenosis.
Purinergic signalling 2006;2(3):471-80.
2005: Qiongman Kong; Min Wang; Zhongji Liao; Jean M Camden; Sue Yu; Agnes Simonyi; Grace Y Sun; Fernando A Gonzalez; Laurie Erb; Cheikh I Seye; Gary A Weisman
P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons.
Purinergic signalling 2005;1(4):337-47.
2005: Min Wang; Qiongman Kong; Fernando A Gonzalez; Grace Sun; Laurie Erb; Cheikh I Seye; Gary A Weisman
P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration.
Journal of neurochemistry 2005;95(3):630-40.
2005: Gary A Weisman; M Wang; Qiongman Kong; Nataliya E Chorna; Joseph T Neary; Grace Y Sun; Fernando A González; Cheikh I Seye; Laurie Erb
Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytes.
Molecular neurobiology 2005;31(1-3):169-83.
2004: Maria Caroline Jacques-Silva; Richard Rodnight; Guido Lenz; Zhongji Liao; Qiongman Kong; Minh D Tran; Yuan Kang; Fernando A Gonzalez; Gary A Weisman; Joseph T Neary
P2X7 receptors stimulate AKT phosphorylation in astrocytes.
British journal of pharmacology 2004;141(7):1106-17.
2003: Cheikh I Seye; Ningpu Yu; Renu Jain; Qiongman Kong; Tess Minor; Jessica Newton; Laurie Erb; Fernando A González; Gary A Weisman
The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells.
The Journal of biological chemistry 2003;278(27):24960-5.
2002: Cheikh I Seye; Qiongman Kong; Laurie Erb; Richard C Garrad; Brent W Krugh; Meifang Wang; John T Turner; Michael Sturek; Fernando A González; Gary A Weisman
Functional P2Y2 nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries.
Circulation 2002;106(21):2720-6.
2002: Fernand-Pierre Gendron; Ouhida Benrezzak; Brent W Krugh; Qiongman Kong; Gary A Weisman; Adrien R Beaudoin
Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition.
Current drug targets 2002;3(3):229-45.
2001: Laurie Erb; Jun Liu; J Ockerhausen; Qiongman Kong; Richard C Garrad; K Griffin; C Neal; Brent W Krugh; Laura I Santiago-Pérez; Fernando A González; H D Gresham; John T Turner; Gary A Weisman
An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction.
The Journal of cell biology 2001;153(3):491-501.