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Stefano Moro

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Siew Lee Cheong; Stephanie Federico; Alexander Laurence Mandel; Stefano Moro; Yi-Ming Shao; Giampiero Spalluto; Gopalakrishnan Venkatesan; Giorgia Pastorin
The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.
Giorgio Cozza; L A Pinna; Stefano Moro
Kinase CK2 inhibition: an update.
Eszter Kozma; Stefano Moro; Silvia Paoletta; Giampiero Spalluto; Lucia Squarcialupi; P Suresh Jayasekara; Stephanie Federico; Kenneth A Jacobson
Fluorescent ligands for adenosine receptors.

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2013: Siew Lee Cheong; Stephanie Federico; Alexander Laurence Mandel; Stefano Moro; Yi-Ming Shao; Giampiero Spalluto; Gopalakrishnan Venkatesan; Giorgia Pastorin
The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.
Medicinal research reviews 2013;33(2):235-335.
2013: Giorgio Cozza; L A Pinna; Stefano Moro
Kinase CK2 inhibition: an update.
Current medicinal chemistry 2013;20(5):671-93.
2013: Eszter Kozma; Stefano Moro; Silvia Paoletta; Giampiero Spalluto; Lucia Squarcialupi; P Suresh Jayasekara; Stephanie Federico; Kenneth A Jacobson
Fluorescent ligands for adenosine receptors.
Bioorganic & medicinal chemistry letters 2013;23(1):26-36.
2012: Stephanie Federico; Karl-Norbert Klotz; Stefano Moro; Silvia Paoletta; Giorgia Pastorin; Davide Sabbadin; Barbara Cacciari; Antonella Ciancetta; Giampiero Spalluto
Exploring the directionality of 5-substitutions in a new series of 5-alkylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine as a strategy to design novel human a(3) adenosine receptor antagonists.
Journal of medicinal chemistry 2012;55(22):9654-68.
2012: Valentina Furlanetto; Stefano Moro; Riccardo Pasquale; Giuseppe Zagotto; Barbara Gatto
Ellagic acid and polyhydroxylated urolithins are potent catalytic inhibitors of human topoisomerase II: an in vitro study.
Journal of agricultural and food chemistry 2012;60(36):9162-70.
2012: Giorgio Cozza; Lorenzo A Pinna; Stefano Moro
Protein kinase CK2 inhibitors: a patent review.
Expert opinion on therapeutic patents 2012;22(9):1081-97.
2012: Vittoria Colotta; Elisabetta Coppi; Chiara Costagli; Alessandro Galli; Carla Ghelardini; Ombretta Lenzi; Giovanna Maraula; Felicita Pedata; Domenico E Pellegrini-Giampietro; Anna Maria Pugliese; Davide Sabbadin; Lucia Squarcialupi; Flavia Varano; Daniela Catarzi; Stefano Moro
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: molecular modeling and pharmacological studies.
European journal of medicinal chemistry 2012;54():470-82.
2012: Alexandra Gaspar; Sonja Kachler; Karl-Norbert Klotz; Stefano Moro; Silvia Paoletta; Joana Reis; Eugenio Uriarte; Fernanda Borges
Discovery of novel A3 adenosine receptor ligands based on chromone scaffold.
Biochemical pharmacology 2012;84(1):21-9.
2012: Eszter Kozma; T Santhosh Kumar; Stefano Moro; Silvia Paoletta; Khai Phan; Giampiero Spalluto; Ramachandran Balasubramanian; Stephanie Federico; Zhan-Guo Gao; Kenneth Alan Jacobson
Novel fluorescent antagonist as a molecular probe in A(3) adenosine receptor binding assays using flow cytometry.
Biochemical pharmacology 2012;83(11):1552-61.
2012: Antonio Girolami; Emanuela Bonamigo; Andrea Cristiani; Stefano Moro; Liliana Santarossa; Pamela Scarparo; Anna Maria Lombardi
A cluster of factor XI-deficient patients due to a new mutation (Ile 436 Lys) in northeastern Italy.
European journal of haematology 2012;88(3):229-36.
2012: Giampietro Viola; Roberta Bortolozzi; Paola Brun; Ignazio Castagliuolo; Maria Grazia Ferlin; Ernest Hamel; Stefano Moro; Giuseppe Basso
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells.
Biochemical pharmacology 2012;83(1):16-26.
2011: Giorgio Cozza; Alessandra Gianoncelli; Flavio Meggio; Riccardo Pasquale; Lorenzo A Pinna; Angelo Rosolen; Giuseppe Zagotto; Elisa Zorzi; Paolo Bonvini; Stefano Moro
Urolithin as a converging scaffold linking ellagic acid and coumarin analogues: design of potent protein kinase CK2 inhibitors.
ChemMedChem 2011;6(12):2273-86.
2011: Simone Bertini; Andrea Bortolato; Elisa Ghilardi; Carlotta Granchi; Clementina Manera; Jonathan Mason; Filippo Minutolo; Stefano Moro; Giuseppe Saccomanni; Valentina Asso; Marco Macchia
Carbazole-containing arylcarboxamides as BACE1 inhibitors.
Bioorganic & medicinal chemistry letters 2011;21(22):6657-61.
2011: Masafumi Inui; Anant Mamidi; Andrea Manfrin; Graziano Martello; Stefano Moro; Leonardo Morsut; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Simona Polo; Sandra Soligo; Stefano Piccolo
USP15 is a deubiquitylating enzyme for receptor-activated SMADs.
Nature cell biology 2011;13(11):1368-75.
2011: Siew Lee Cheong; Anton V Dolzhenko; Anna V Dolzhenko; Stephanie Federico; Sonja Kachler; Karl-Norbert Klotz; Evelyn Pei Rong Lee; Stefano Moro; Silvia Paoletta; Giampiero Spalluto; Giorgia Pastorin
Does the combination of optimal substitutions at the C²-, N⁵- and N⁸-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A₃ adenosine receptors?
Bioorganic & medicinal chemistry 2011;19(20):6120-34.
2011: Magdalena Bacilieri; Monica Ceol; Maura Comoli; Stefano Moro; Annamaria Naggi; Manlio Palumbo; Erwin D Schleicher; Giangiacomo Torri; Enrica Tosetto; Giovanni Gambaro
Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: biochemical and structural considerations.
Glycobiology 2011;21(8):1029-37.
2011: Andrea Cristiani; Flavio Meggio; Giorgio Costa; Giorgio Cozza; Leonardo Scapozza; Stefano Moro
The role of the N-terminal domain in the regulation of the "constitutively active" conformation of protein kinase CK2α: insight from a molecular dynamics investigation.
ChemMedChem 2011;6(7):1207-16.
2011: Matteo Floris; Joel Masciocchi; Marco Fanton; Stefano Moro
Swimming into peptidomimetic chemical space using pepMMsMIMIC.
Nucleic acids research 2011;39(Web Server issue):W261-9.
2011: Daniela Poli; Daniela Catarzi; Vittoria Colotta; Flavia Varano; Guido Filacchioni; Simona Daniele; Letizia Trincavelli; Claudia Martini; Silvia Paoletta; Stefano Moro
The identification of the 2-phenylphthalazin-1(2H)-one scaffold as a new decorable core skeleton for the design of potent and selective human A3 adenosine receptor antagonists.
Journal of medicinal chemistry 2011;54(7):2102-13.
2011: Stephanie Federico; Zhan-Guo Gao; Kenneth Alan Jacobson; Karl-Norbert Klotz; Stefano Moro; Silvia Paoletta; Giorgia Pastorin; Jeffrey Siegel; Barbara Cacciari; Siew Lee Cheong; Stefano Stragliotto; Giampiero Spalluto
Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
Journal of medicinal chemistry 2011;54(3):877-89.
2011: Giorgio Cozza; Flavio Meggio; Stefano Moro
The dark side of protein kinase CK2 inhibition.
Current medicinal chemistry 2011;18(19):2867-84.
2011: Stefano M Marino; Stefano Fogal; Marco Bisaglia; Stefano Moro; Guido Scartabelli; Luca De Gioia; Alessia Spada; Enrico Monzani; Luigi Casella; Stefano Mammi; Luigi Bubacco
Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols.
Archives of biochemistry and biophysics 2011;505(1):67-74.
2010: Simone Bertini; Elisa Ghilardi; Valentina Asso; Carlotta Granchi; Filippo Minutolo; Mauro Pineschi; Valeria Di Bussolo; Andrea Bortolato; Stefano Moro; Alessandro Saba; Marco Macchia
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides.
Bioorganic & medicinal chemistry 2010;18(22):7991-6.
2010: Alessandra Gianoncelli; Serena Basili; Matteo Scalabrin; Alice Sosic; Stefano Moro; Giuseppe Zagotto; Manlio Palumbo; Nohad Gresh; Barbara Gatto
Rational design, synthesis, and DNA binding properties of novel sequence-selective peptidyl congeners of ametantrone.
ChemMedChem 2010;5(7):1080-91.
2010: Lisa Michielan; Stefano Moro
Pharmaceutical perspectives of nonlinear QSAR strategies.
Journal of chemical information and modeling 2010;50(6):961-78.
2010: Giorgio Cozza; Andrea Bortolato; Stefano Moro
How druggable is protein kinase CK2?
Medicinal research reviews 2010;30(3):419-62.
2010: Silvia Paoletta; Stephanie Federico; Giampiero Spalluto; Stefano Moro
Receptor-driven identification of novel human A₃ adenosine receptor antagonists as potential therapeutic agents.
Methods in enzymology 2010;485():225-44.
2010: Luigi Quintieri; Sara Bortolozzo; Stefano Stragliotto; Stefano Moro; Martina Pavanetto; Alberto Nassi; Pietro Palatini; Maura Floreani
Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.
Drug metabolism and pharmacokinetics 2010;25(5):466-76.
2009: Ombretta Lenzi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Daniela Poli; Guido Filacchioni; Katia Varani; Fabrizio Vincenzi; Pier Andrea Borea; Silvia Paoletta; Erika Morizzo; Stefano Moro
2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition.
Journal of medicinal chemistry 2009;52(23):7640-52.
2009: Lisa Michielan; Federico Stephanie; Lothar Terfloth; Dimitar Hristozov; Barbara Cacciari; Karl-Norbert Klotz; Giampiero Spalluto; Johann Gasteiger; Stefano Moro
Exploring potency and selectivity receptor antagonist profiles using a multilabel classification approach: the human adenosine receptors as a key study.
Journal of chemical information and modeling 2009;49(12):2820-36.
2009: Lisa Michielan; Lothar Terfloth; Johann Gasteiger; Stefano Moro
Comparison of multilabel and single-label classification applied to the prediction of the isoform specificity of cytochrome p450 substrates.
Journal of chemical information and modeling 2009;49(11):2588-605.
2009: Giorgio Cozza; Andrea Bortolato; Ernesto Menta; Ennio Cavalletti; Silvano Spinelli; Stefano Moro
ATP non-competitive Ser/Thr kinase inhibitors as potential anticancer agents.
Anti-cancer agents in medicinal chemistry 2009;9(7):778-86.
2009: Giorgio Cozza; Marco Mazzorana; Elena Papinutto; Jenny Bain; Matthew Elliott; Giovanni Di Maira; Alessandra Gianoncelli; Mario Angelo Pagano; Stefania Sarno; Maria Ruzzene; Roberto Battistutta; Flavio Meggio; Stefano Moro; Giuseppe Zagotto; Lorenzo A Pinna
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2.
The Biochemical journal 2009;421(3):387-95.
2009: Lisa Michielan; Chiara Bolcato; Stephanie Federico; Barbara Cacciari; Magdalena Bacilieri; Karl-Norbert Klotz; Sonja Kachler; Giorgia Pastorin; Riccardo Cardin; Alessandro Sperduti; Giampiero Spalluto; Stefano Moro
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites.
Bioorganic & medicinal chemistry 2009;17(14):5259-74.
2009: Serena Basili; Stefano Moro
Novel camptothecin derivatives as topoisomerase I inhibitors.
Expert opinion on therapeutic patents 2009;19(5):555-74.
2009: Vittoria Colotta; Ombretta Lenzi; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Osele Ciampi; Anna Maria Pugliese; Chiara Traini; Felicita Pedata; Erika Morizzo; Stefano Moro
Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2009;52(8):2407-19.
2009: Sara N Richter; Ileana Menegazzo; Matteo Nadai; Stefano Moro; Manlio Palumbo
Reactivity of clerocidin towards adenine: implications for base-modulated DNA damage.
Organic & biomolecular chemistry 2009;7(5):976-85.
2009: Sirio Dupont; Anant Mamidi; Michelangelo Cordenonsi; Marco Montagner; Luca Zacchigna; Maddalena Adorno; Graziano Martello; Michael J Stinchfield; Sandra Soligo; Leonardo Morsut; Masafumi Inui; Stefano Moro; Nicola Modena; Francesco Argenton; Stuart J Newfeld; Stefano Piccolo
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.
Cell 2009;136(1):123-35.
2009: Erika Morizzo; Stephanie Federico; Giampiero Spalluto; Stefano Moro
Human A3 adenosine receptor as versatile G protein-coupled receptor example to validate the receptor homology modeling technology.
Current pharmaceutical design 2009;15(35):4069-84.
2008: Serena Basili; Giuseppe Basso; Anita Faccio; Anton Granzhan; Heiko Ihmels; Stefano Moro; Giampietro Viola
Diazoniapolycyclic ions inhibit the activity of topoisomerase I and the growth of certain tumor cell lines.
ChemMedChem 2008;3(11):1671-6.
2008: Giorgio Cozza; Alessandra Gianoncelli; Monica Montopoli; Laura Caparrotta; Andrea Venerando; Flavio Meggio; Lorenzo A Pinna; Giuseppe Zagotto; Stefano Moro
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Bioorganic & medicinal chemistry letters 2008;18(20):5672-5.
2008: Andrea Bortolato; Giorgio Cozza; Stefano Moro
Protein kinase CK2 inhibitors: emerging anticancer therapeutic agents?
Anti-cancer agents in medicinal chemistry 2008;8(7):798-806.
2008: Valentina Asso; Elisa Ghilardi; Simone Bertini; Maria Digiacomo; Carlotta Granchi; Filippo Minutolo; Simona Rapposelli; Andrea Bortolato; Stefano Moro; Marco Macchia
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.
ChemMedChem 2008;3(10):1530-4.
2008: Carla Bazzicalupi; Andrea Bencini; Claudia Bonaccini; Claudia Giorgi; Paola Gratteri; Stefano Moro; Manlio Palumbo; Alessandro Simionato; Jacopo Sgrignani; Claudia Sissi; Barbara Valtancoli
Tuning the activity of Zn(II) complexes in DNA cleavage: clues for design of new efficient metallo-hydrolases.
Inorganic chemistry 2008;47(12):5473-84.
2008: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Ombretta Lenzi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Osele Ciampi; Chiara Traini; Anna Maria Pugliese; Felicita Pedata; Erika Morizzo; Stefano Moro
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2008;16(11):6086-102.
2008: Lisa Michielan; Magdalena Bacilieri; Chosei Kaseda; Stefano Moro
Prediction of the aqueous solvation free energy of organic compounds by using autocorrelation of molecular electrostatic potential surface properties combined with response surface analysis.
Bioorganic & medicinal chemistry 2008;16(10):5733-42.
2008: Andrea Bortolato; Stefano Moro
Designing a ligand for pharmaceutical purposes.
Expert opinion on drug discovery 2008;3(5):579-90.
2008: Chiara Bolcato; Claudia Cusan; Giorgia Pastorin; Giampiero Spalluto; Barbara Cacciari; Karl-Norbert Klotz; Erika Morizzo; Stefano Moro
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes.
Purinergic signalling 2008;4(1):39-46.
2008: Adriana Chilin; Roberto Battistutta; Andrea Bortolato; Giorgio Cozza; Samuele Zanatta; Giorgia Poletto; Marco Mazzorana; Giuseppe Zagotto; Eugenio Uriarte; Andrea Guiotto; Lorenzo A Pinna; Flavio Meggio; Stefano Moro
Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
Journal of medicinal chemistry 2008;51(4):752-9.
2008: Lisa Michielan; Magdalena Bacilieri; Andrea Schiesaro; Chiara Bolcato; Giorgia Pastorin; Giampiero Spalluto; Barbara Cacciari; Karl-Norbert Klotz; Chosei Kaseda; Stefano Moro
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo-pyrimidine antagonists binding site of the human adenosine A2A receptor.
Journal of chemical information and modeling 2008;48(2):350-63.
2008: Giuseppe Zagotto; Claudia Sissi; Stefano Moro; Diego Dal Ben; Gary N Parkinson; Keith R Fox; Stephen Neidle; Manlio Palumbo
Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives.
Bioorganic & medicinal chemistry 2008;16(1):354-61.
2008: Giorgio Cozza; Stefano Moro; Giovanni Gotte
Elucidation of the ribonuclease A aggregation process mediated by 3D domain swapping: a computational approach reveals possible new multimeric structures.
Biopolymers 2008;89(1):26-39.
2007: Erika Morizzo; Francesca Capelli; Ombretta Lenzi; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Fabrizio Vincenzi; Katia Varani; Pier Andrea Borea; Vittoria Colotta; Stefano Moro
Scouting human A3 adenosine receptor antagonist binding mode using a molecular simplification approach: from triazoloquinoxaline to a pyrimidine skeleton as a key study.
Journal of medicinal chemistry 2007;50(26):6596-606.
2007: Serena Basili; Anna Bergen; Francesco Dall'Acqua; Anita Faccio; Anton Granzhan; Heiko Ihmels; Stefano Moro; Giampietro Viola
Relationship between the structure and the DNA binding properties of diazoniapolycyclic duplex- and triplex-DNA binders: efficiency, selectivity, and binding mode.
Biochemistry 2007;46(44):12721-36.
2007: Roberto Battistutta; Marco Mazzorana; Laura Cendron; Andrea Bortolato; Stefania Sarno; Zygmunt Kazimierczuk; Giuseppe Zanotti; Stefano Moro; Lorenzo A Pinna
The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules.
Chembiochem : a European journal of chemical biology 2007;8(15):1804-9.
2007: Magdalena Bacilieri; Flavia Varano; Francesca Deflorian; M Marini; Daniela Catarzi; Vittoria Colotta; Guido Filacchioni; A Galli; Chiara Costagli; C Kaseda; Stefano Moro
Tandem 3D-QSARs approach as a valuable tool to predict binding affinity data: design of new Gly/NMDA receptor antagonists as a key study.
Journal of chemical information and modeling 2007;47(5):1913-22.
2007: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Francesca Capelli; Ombretta Lenzi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Osele Ciampi; Anna Maria Pugliese; Felicita Pedata; Andrea Schiesaro; Erika Morizzo; Stefano Moro
New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2007;50(17):4061-74.
2007: Barbara Cacciari; Chiara Bolcato; Giampiero Spalluto; Karl-Norbert Klotz; Magdalena Bacilieri; Francesca Deflorian; Stefano Moro
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure-activity profile.
Purinergic signalling 2007;3(3):183-93.
2007: A Bortolato; Stefano Moro
In silico binding free energy predictability by using the linear interaction energy (LIE) method: bromobenzimidazole CK2 inhibitors as a case study.
Journal of chemical information and modeling 2007;47(2):572-82.
2007: Gloria Cristalli; Barbara Cacciari; Diego Dal Ben; Catia Lambertucci; Stefano Moro; Giampiero Spalluto; Rosaria Volpini
Highlights on the development of A(2A) adenosine receptor agonists and antagonists.
ChemMedChem 2007;2(3):260-81.
2007: Mario Angelo Pagano; Giorgia Poletto; Giovanni Di Maira; Giorgio Cozza; Maria Ruzzene; Stefania Sarno; Jenny Bain; Matthew Elliott; Stefano Moro; Giuseppe Zagotto; Flavio Meggio; Lorenzo A Pinna
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(1):129-39.
2007: Stefano Moro; Magdalena Bacilieri; Francesca Deflorian
Combining ligand-based and structure-based drug design in the virtual screening arena.
Expert opinion on drug discovery 2007;2(1):37-49.
2007: Diego Dal Ben; Manlio Palumbo; Giuseppe Zagotto; Giovanni Capranico; Stefano Moro
DNA topoisomerase II structures and anthracycline activity: insights into ternary complex formation.
Current pharmaceutical design 2007;13(27):2766-80.
2006: Heiko Ihmels; Daniela Otto; Francesco Dall'Acqua; Anita Faccio; Stefano Moro; Giampietro Viola
Comparative studies on the DNA-binding properties of linear and angular dibenzoquinolizinium ions.
The Journal of organic chemistry 2006;71(22):8401-11.
2006: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Ombretta Lenzi; Guido Filacchioni; Chiara Costagli; Alessandro Galli; Carla Ghelardini; Nicoletta Galeotti; Paola Gratteri; Jacopo Sgrignani; Francesca Deflorian; Stefano Moro
Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies.
Journal of medicinal chemistry 2006;49(20):6015-26.
2006: Magdalena Bacilieri; Stefano Moro
Ligand-based drug design methodologies in drug discovery process: an overview.
Current drug discovery technologies 2006;3(3):155-65.
2006: Stefano Moro; Magdalena Bacilieri; Barbara Cacciari; Chiara Bolcato; Claudia Cusan; Giorgia Pastorin; Karl-Norbert Klotz; Giampiero Spalluto
The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: application to a lead optimization of a human A3 adenosine receptor antagonist.
Bioorganic & medicinal chemistry 2006;14(14):4923-32.
2006: Ombretta Lenzi; Vittoria Colotta; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Osele Ciampi; Katia Varani; Federico Marighetti; Erika Morizzo; Stefano Moro
4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2006;49(13):3916-25.
2006: Giorgio Cozza; Paolo Bonvini; Elisa Zorzi; Giorgia Poletto; Mario Angelo Pagano; Stefania Sarno; Arianna Donella-Deana; Giuseppe Zagotto; Angelo Rosolen; Lorenzo A Pinna; Flavio Meggio; Stefano Moro
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.
Journal of medicinal chemistry 2006;49(8):2363-6.
2006: Giorgia Pastorin; Tatiana Da Ros; Chiara Bolcato; Christian Montopoli; Stefano Moro; Barbara Cacciari; Pier Giovanni Baraldi; Katia Varani; Pier Andrea Borea; Giampiero Spalluto
Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations.
Journal of medicinal chemistry 2006;49(5):1720-9.
2006: Stefano Moro; Zhan-Guo Gao; Kenneth Alan Jacobson; Giampiero Spalluto
Progress in the pursuit of therapeutic adenosine receptor antagonists.
Medicinal research reviews 2006;26(2):131-59.
2006: Stefano Moro; Francesca Deflorian; Magdalena Bacilieri; Giampiero Spalluto
Ligand-based homology modeling as attractive tool to inspect GPCR structural plasticity.
Current pharmaceutical design 2006;12(17):2175-85.
2006: Stefano Moro; Francesca Deflorian; Magdalena Bacilieri; Giampiero Spalluto
Novel strategies for the design of new potent and selective human A3 receptor antagonists: an update.
Current medicinal chemistry 2006;13(6):639-45.
2005: Daniela Catarzi; Vittoria Colotta; Flavia Varano; Ombretta Lenzi; Guido Filacchioni; Letizia Trincavelli; Claudia Martini; Christian Montopoli; Stefano Moro
1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.
Journal of medicinal chemistry 2005;48(25):7932-45.
2005: Barbara Cacciari; Giorgia Pastorin; Chiara Bolcato; Giampiero Spalluto; Magdalena Bacilieri; Stefano Moro
A2B adenosine receptor antagonists: recent developments.
Mini reviews in medicinal chemistry 2005;5(12):1053-60.
2005: Flavia Varano; Daniela Catarzi; Vittoria Colotta; Francesca Romana Calabri; Ombretta Lenzi; Guido Filacchioni; Alessandro Galli; Chiara Costagli; Francesca Deflorian; Stefano Moro
1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: synthesis, biological evaluation, and molecular modeling study.
Bioorganic & medicinal chemistry 2005;13(19):5536-49.
2005: Stefano Moro; Magdalena Bacilieri; Barbara Cacciari; Giampiero Spalluto
Autocorrelation of molecular electrostatic potential surface properties combined with partial least squares analysis as new strategy for the prediction of the activity of human A(3) adenosine receptor antagonists.
Journal of medicinal chemistry 2005;48(18):5698-704.
2005: Giorgia Pastorin; Chiara Bolcato; Barbara Cacciari; Sonja Kachler; Karl-Norbert Klotz; Christian Montopoli; Stefano Moro; Giampiero Spalluto
Synthesis, biological and modeling studies of 1,3-di-n-propyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as adenosine receptor antagonists.
Farmaco (Società chimica italiana : 1989) 2005;60(8):643-51.
2005: Maria Grazia Ferlin; Cristina Marzano; Lisa Dalla Via; Adriana Chilin; Giuseppe Zagotto; Andrea Guiotto; Stefano Moro
New water soluble pyrroloquinoline derivatives as new potential anticancer agents.
Bioorganic & medicinal chemistry 2005;13(15):4733-9.
2005: Erika Del Grosso; donatella boschi; Loretta Lazzarato; Clara Cena; Antonella Di Stilo; Roberta Fruttero; Stefano Moro; Alberto Gasco
The furoxan system: design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasodilating activities.
Chemistry & biodiversity 2005;2(7):886-900.
2005: Alessandro Brigo; Gabriela Iurcu Mustata; James M Briggs; Stefano Moro
Discovery of HIV-1 integrase inhibitors through a novel combination of ligand and structure-based drug design.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(3):263-75.
2005: Giorgia Pastorin; Chiara Bolcato; Barbara Cacciari; Sonja Kachler; Karl-Norbert Klotz; Christian Montopoli; Stefano Moro; Giampiero Spalluto
Synthesis, biological studies and molecular modeling investigation of 1,3-dimethyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as potential adenosine receptor antagonists.
Farmaco (Società chimica italiana : 1989) 2005;60(4):299-306.
2005: Stefano Moro; Magdalena Bacilieri; Cristina Ferrari; Giampiero Spalluto
Autocorrelation of molecular electrostatic potential surface properties combined with partial least squares analysis as alternative attractive tool to generate ligand-based 3D-QSARs.
Current drug discovery technologies 2005;2(1):13-21.
2005: Daniela Catarzi; Vittoria Colotta; Flavia Varano; Francesca Romana Calabri; Ombretta Lenzi; Guido Filacchioni; Letizia Trincavelli; Claudia Martini; Andrea Tralli; Christian Montopoli; Stefano Moro
2-aryl-8-chloro-1,2,4-triazolo[1,5-a]quinoxalin-4-amines as highly potent A1 and A3 adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2005;13(3):705-15.
2005: Mine Yarim; Stefano Moro; Robert Huber; Peter J Meier Abt; Chosei Kaseda; Toru Kashima; Bruno Hagenbuch; Gerd Folkers
Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates.
Bioorganic & medicinal chemistry 2005;13(2):463-71.
2005: Stefano Moro; Paolo Braiuca; Francesca Deflorian; Cristina Ferrari; Giorgia Pastorin; Barbara Cacciari; Pier Giovanni Baraldi; Katia Varani; Pier Andrea Borea; Giampiero Spalluto
Combined target-based and ligand-based drug design approach as a tool to define a novel 3D-pharmacophore model of human A3 adenosine receptor antagonists: pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as a key study.
Journal of medicinal chemistry 2005;48(1):152-62.
2005: Sara N Richter; Daniele Fabris; Stefano Moro; Manlio Palumbo
Dissecting reactivity of clerocidin toward common buffer systems by means of selected drug analogues.
Chemical research in toxicology 2005;18(1):35-40.
2005: Stefano Moro; Giampiero Spalluto; Kenneth Alan Jacobson
Techniques: Recent developments in computer-aided engineering of GPCR ligands using the human adenosine A3 receptor as an example.
Trends in pharmacological sciences 2005;26(1):44-51.
2004: Susanna Bosi; Luigi Feruglio; Tatiana Da Ros; Giampiero Spalluto; Barbara Gregoretti; Michela Terdoslavich; Giuliana Decorti; Sabina Passamonti; Stefano Moro; Maurizio Prato
Hemolytic effects of water-soluble fullerene derivatives.
Journal of medicinal chemistry 2004;47(27):6711-5.
2004: Flavio Meggio; Mario Angelo Pagano; Stefano Moro; Giuseppe Zagotto; Maria Ruzzene; Stefania Sarno; Giorgio Cozza; Jenny Bain; Matthew Elliott; Arianna Donella Deana; Anna Maria Brunati; Lorenzo A Pinna
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study.
Biochemistry 2004;43(40):12931-6.
2004: Andrea Guiotto; Mirta Canevari; Michela Pozzobon; Stefano Moro; Piero Orsolini; Francesco M Veronese
Anchimeric assistance effect on regioselective hydrolysis of branched PEGs: a mechanistic investigation.
Bioorganic & medicinal chemistry 2004;12(19):5031-7.
2004: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Francesca Romana Calabri; Ombretta Lenzi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Francesca Deflorian; Stefano Moro
1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2004;47(14):3580-90.
2004: Stefano Moro; Giovanni L Beretta; Diego Dal Ben; John L. Nitiss; Manlio Palumbo; Giovanni Capranico
Interaction model for anthracycline activity against DNA topoisomerase II.
Biochemistry 2004;43(23):7503-13.
2004: Elisa Boseggia; Maddalena Gatos; Lorena Lucatello; Fabrizio Mancin; Stefano Moro; Manlio Palumbo; Claudia Sissi; Paolo Tecilla; Umberto Tonellato; Giuseppe Zagotto
Toward efficient Zn(II)-based artificial nucleases.
Journal of the American Chemical Society 2004;126(14):4543-9.
2004: Claudia Sissi; Elisabetta Leo; Stefano Moro; Giovanni Capranico; Annalaura Mancia; Ernesto Menta; A Paul Krapcho; Manlio Palumbo
Antitumor AZA-anthrapyrazoles: biophysical and biochemical studies on 8- and 9-aza regioisomers.
Biochemical pharmacology 2004;67(4):631-42.
2004: Oddone Schiavon; Gianfranco Pasut; Stefano Moro; Piero Orsolini; Andrea Guiotto; Francesco M Veronese
PEG-Ara-C conjugates for controlled release.
European journal of medicinal chemistry 2004;39(2):123-33.
2004: Daniela Vedaldi; Alessandro Dolmella; Stefano Moro; Giorgia Miolo; Giampietro Viola; Sergio Caffieri; Francesco Dall'Acqua
1-Thioangelicin: crystal structure, computer-aided studies and photobiological activity.
Farmaco (Società chimica italiana : 1989) 2004;59(2):125-32.
2003: Stefano Moro; Francesca Deflorian; Giampiero Spalluto; Giorgia Pastorin; Barbara Cacciari; Soo-Kyung Kim; Kenneth Alan Jacobson
Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling.
Chemical communications (Cambridge, England) 2003;(24):2949-56.
2003: Giorgia Pastorin; Tatiana Da Ros; Giampiero Spalluto; Francesca Deflorian; Stefano Moro; Barbara Cacciari; Pier Giovanni Baraldi; Stefania Gessi; Katia Varani; Pier Andrea Borea
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Journal of medicinal chemistry 2003;46(20):4287-96.
2003: Paolo Pengo; Lucia Pasquato; Stefano Moro; Alessandro Brigo; Federico Fogolari; Quirinus B Broxterman; Bernard Kaptein; Paolo Scrimin
Quantitative correlation of solvent polarity with the alpha-/3(10)-helix equilibrium: a heptapeptide behaves as a solvent-driven molecular spring.
Angewandte Chemie (International ed. in English) 2003;42(29):3388-92.
2003: Erika De Moliner; Stefano Moro; Stefania Sarno; Giuseppe Zagotto; Giuseppe Zanotti; Lorenzo A Pinna; Roberto Battistutta
Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.
The Journal of biological chemistry 2003;278(3):1831-6.
2002: Anna Maconi; Giorgia Pastorin; Tatiana Da Ros; Giampiero Spalluto; Zhan-Guo Gao; Kenneth Alan Jacobson; Pier Giovanni Baraldi; Barbara Cacciari; Katia Varani; Stefano Moro; Pier Andrea Borea
Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist.
Journal of medicinal chemistry 2002;45(17):3579-82.
2002: Manlio Palumbo; Barbara Gatto; Stefano Moro; Claudia Sissi; Giuseppe Zagotto
Sequence-specific interactions of drugs interfering with the topoisomerase-DNA cleavage complex.
Biochimica et biophysica acta 2002;1587(2-3):145-54.
2002: Giampietro Viola; Francesco Dall'Acqua; Nadia Gabellini; Stefano Moro; Daniela Vedaldi; Heiko Ihmels
Indolo[2,3-b]-quinolizinium bromide: an efficient intercalator with DNA-photodamaging properties.
Chembiochem : a European journal of chemical biology 2002;3(6):550-8.
2002: Pier Giovanni Baraldi; Barbara Cacciari; Stefano Moro; Giampiero Spalluto; Giorgia Pastorin; Tatiana Da Ros; Karl-Norbert Klotz; Katia Varani; Stefania Gessi; Pier Andrea Borea
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists.
Journal of medicinal chemistry 2002;45(4):770-80.
2002: Stefania Sarno; Stefano Moro; Flavio Meggio; Giuseppe Zagotto; Diego Dal Ben; Paola Ghisellini; Roberto Battistutta; Giuseppe Zanotti; Lorenzo A Pinna
Toward the rational design of protein kinase casein kinase-2 inhibitors.
Pharmacology & therapeutics 2002;93(2-3):159-68.
2002: Stefano Moro; Kenneth Alan Jacobson
Molecular modeling as a tool to investigate molecular recognition in P2Y receptors.
Current pharmaceutical design 2002;8(26):2401-13.
2002: Kenneth Alan Jacobson; Stefano Moro; John A Manthey; Patrick L West; Xiao-Duo Ji
Interactions of flavones and other phytochemicals with adenosine receptors.
Advances in experimental medicine and biology 2002;505():163-71.
2002: Pier Giovanni Baraldi; Rimma Makaeva; Maria Giovanna Pavani; Maria del Carmen Nuñez; Giampiero Spalluto; Stefano Moro; Simonetta Falzoni; Francesco Di Virgilio; LUISA-CARLOTA LÓPEZ-CARA
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor containing a tyrosine moiety.
Arzneimittel-Forschung 2002;52(4):273-85.
2001: Giuseppe Zagotto; Barbara Gatto; Stefano Moro; Claudia Sissi; Manlio Palumbo
Anthracyclines: recent developments in their separation and quantitation.
Journal of chromatography. B, Biomedical sciences and applications 2001;764(1-2):161-71.
2001: Manlio Palumbo; Claudia Sissi; Barbara Gatto; Stefano Moro; Giuseppe Zagotto
Quantitation of camptothecin and related compounds.
Journal of chromatography. B, Biomedical sciences and applications 2001;764(1-2):121-40.
2001: Barbara Gatto; Sara N Richter; Stefano Moro; Giovanni Capranico; Manlio Palumbo
The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage.
Nucleic acids research 2001;29(20):4224-30.
2001: Pier Giovanni Baraldi; Barbara Cacciari; Stefano Moro; LUISA-CARLOTA LÓPEZ-CARA; Kenneth Alan Jacobson; Stefania Gessi; Pier Andrea Borea; Giampiero Spalluto
Fluorosulfonyl- and bis-(beta-chloroethyl)amino-phenylamino functionalized pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: irreversible antagonists at the human A3 adenosine receptor and molecular modeling studies.
Journal of medicinal chemistry 2001;44(17):2735-42.
2001: Kenneth Alan Jacobson; R Gnana Ravi; Nandanan Erathodiyil; Hak-Sung Kim; Stefano Moro; YC Kim; Kyeong Lee; Dov Barak; Victor E Marquez; Xiao-Duo Ji
Ribose modified nucleosides and nucleotides as ligands for purine receptors.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):333-41.
2001: Kenneth Alan Jacobson; Stefano Moro; C Hoffmann; Y C Kim; H S Kim; R G Ravi; T Kendall Harden; J L Boyer
Structurally related nucleotides as selective agonists and antagonists at P2Y1 receptors.
Farmaco (Società chimica italiana : 1989) 2001;56(1-2):71-5.
2001: Claudia Sissi; Stefano Moro; Sara N Richter; Barbara Gatto; Ernesto Menta; S Spinelli; A Paul Krapcho; Franco Zunino; Manlio Palumbo
DNA-interactive anticancer aza-anthrapyrazoles: biophysical and biochemical studies relevant to the mechanism of action.
Molecular pharmacology 2001;59(1):96-103.
2000: P G Baraldi; Barbara Cacciari; R Romagnoli; Giampiero Spalluto; Stefano Moro; Karl-Norbert Klotz; E Leung; K Varani; Stefania Gessi; Stefania Merighi; P A Borea
Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: influence of the chain at the N(8) pyrazole nitrogen.
Journal of medicinal chemistry 2000;43(25):4768-80.
2000: Violetta Cecchetti; Cristina Parolin; Stefano Moro; Teresa Pecere; Enrica Filipponi; Arianna Calistri; Oriana Tabarrini; Barbara Gatto; Manlio Palumbo; Arnaldo Fravolini; G Palu'
6-Aminoquinolones as new potential anti-HIV agents.
Journal of medicinal chemistry 2000;43(20):3799-802.
2000: Valeria Conte; Olga Bortolini; Mauro Carraro; Stefano Moro
Models for the active site of vanadium-dependent haloperoxidases: insight into the solution structure of peroxo vanadium compounds.
Journal of inorganic biochemistry 2000;80(1-2):41-9.
2000: Giampietro Viola; Eugenio Uriarte; Ornella Gia; Stefano Moro
Interactions between DNA and benzo- and tetrahydrobenzofurocoumarins: thermodynamic and molecular modeling studies.
Farmaco (Società chimica italiana : 1989) 2000;55(4):276-86.
2000: Nandanan Erathodiyil; SY Jang; Stefano Moro; Hea Ok Kim; M A Siddiqui; P Russ; Victor E Marquez; R Busson; Piet Herdewijn; T Kendall Harden; José L Boyer; Kenneth Alan Jacobson
Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.
Journal of medicinal chemistry 2000;43(5):829-42.
2000: Giuseppe Zagotto; Rosanna Supino; Enrica Favini; Stefano Moro; Manlio Palumbo
New 1,4-anthracene-9,10-dione derivatives as potential anticancer agents.
Farmaco (Società chimica italiana : 1989) 2000;55(1):1-5.
2000: E Soldaini; Susan John; Stefano Moro; Julie Bollenbacher; U Schindler; Warren J Leonard
DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.
Molecular and cellular biology 2000;20(1):389-401.
1999: Giorgia Miolo; Stefano Moro; Daniela Vedaldi; Sergio Caffieri; Andrea Guiotto; Francesco Dall'Acqua
New benzoquinolizin-5-one derivatives as furocoumarin analogs: DNA-interactions and molecular modeling studies.
Farmaco (Società chimica italiana : 1989) 1999;54(8):551-61.
1999: J Jiang; AH Li; SY Jang; LengChee Chang; Neli Melman; Stefano Moro; X d Ji; E B Lobkovsky; J C Clardy; Kenneth Alan Jacobson
Chiral resolution and stereospecificity of 6-phenyl-4-phenylethynyl- 1,4-dihydropyridines as selective A(3) adenosine receptor antagonists.
Journal of medicinal chemistry 1999;42(16):3055-65.
1999: Claudia Sissi; Stefano Moro; Giuseppe Zagotto; M Ellis; A Paul Krapcho; Ernesto Menta; Manlio Palumbo
Binding of bis-substituted 2-aza-anthracenedione regioisomers to DNA: effects of the relative positioning of the side chains.
Anti-cancer drug design 1999;14(3):265-74.
1999: C Hoffmann; Stefano Moro; Robert A Nicholas; T Kendall Harden; Kenneth Alan Jacobson
The role of amino acids in extracellular loops of the human P2Y1 receptor in surface expression and activation processes.
The Journal of biological chemistry 1999;274(21):14639-47.
1999: Stefano Moro; C Hoffmann; Kenneth Alan Jacobson
Role of the extracellular loops of G protein-coupled receptors in ligand recognition: a molecular modeling study of the human P2Y1 receptor.
Biochemistry 1999;38(12):3498-507.
1999: AH Li; Stefano Moro; N Forsyth; Neli Melman; Xiao-Duo Ji; Kenneth Alan Jacobson
Synthesis, CoMFA analysis, and receptor docking of 3,5-diacyl-2, 4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
Journal of medicinal chemistry 1999;42(4):706-21.
1999: Kenneth Alan Jacobson; C Hoffmann; YC Kim; E Camaioni; Nandanan Erathodiyil; SY Jang; D P Guo; Xiao-Duo Ji; Ivar von Kügelgen; Stefano Moro; A U Ziganshin; Alexey V Rychkov; BF King; S G Brown; Scott S Wildman; Geoffrey Burnstock; José L Boyer; A Mohanram; T Kendall Harden
Molecular recognition in P2 receptors: ligand development aided by molecular modeling and mutagenesis.
Progress in brain research 1999;120():119-32.
1998: Claudia Sissi; L Bolgan; Stefano Moro; Giuseppe Zagotto; Christian Bailly; Ernesto Menta; Giovanni Capranico; Manlio Palumbo
DNA-binding preferences of bisantrene analogues: relevance to the sequence specificity of drug-mediated topoisomerase II poisoning.
Molecular pharmacology 1998;54(6):1036-45.
1998: Stefano Moro; AH Li; Kenneth Alan Jacobson
Molecular modeling studies of human A3 adenosine antagonists: structural homology and receptor docking.
Journal of chemical information and computer sciences 1998;38(6):1239-48.
1998: AH Li; Neli Melman; Stefano Moro; Xiao-Duo Ji; Kenneth Alan Jacobson
Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
Journal of medicinal chemistry 1998;41(17):3186-201.
1998: YC Kim; M de Zwart; LengChee Chang; Stefano Moro; Jacobien K Von Frijtag Drabbe Künzel; Neli Melman; Adriaan P IJzerman; Kenneth Alan Jacobson
Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes.
Journal of medicinal chemistry 1998;41(15):2835-45.
1998: Giovanni Capranico; F Guano; Stefano Moro; Giuseppe Zagotto; Claudia Sissi; Barbara Gatto; Franco Zunino; Ernesto Menta; Manlio Palumbo
Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners.
The Journal of biological chemistry 1998;273(21):12732-9.
1998: Stefano Moro; D Guo; E Camaioni; José L Boyer; T Kendall Harden; Kenneth Alan Jacobson
Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites.
Journal of medicinal chemistry 1998;41(9):1456-66.
1998: Stefano Moro; AM van Rhee; L H Sanders; Kenneth Alan Jacobson
Flavonoid derivatives as adenosine receptor antagonists: a comparison of the hypothetical receptor binding site based on a comparative molecular field analysis model.
Journal of medicinal chemistry 1998;41(1):46-52.
1997: Daniela Vedaldi; G Piazza; Stefano Moro; Sergio Caffieri; Giorgia Miolo; Gian Gaetano Aloisi; Fausto Elisei; Francesco Dall'Acqua
1-Thiopsoralen, a new photobiologically active heteropsoralen. Photophysical, photochemical and computer aided studies.
Farmaco (Società chimica italiana : 1989) 1997;52(11):645-52.
1997: Giuseppe Zagotto; Stefano Moro; Eugenio Uriarte; Eros Ferrazzi; G Palù; Manlio Palumbo
Amido analogs of mitoxantrone: physico-chemical properties, molecular modeling, cellular effects and antineoplastic potential.
Anti-cancer drug design 1997;12(2):99-112.