Werner Muller

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Salguero Gustavo; Schuett Harald; Jagielska Joanna; Schley René; Tallone Ezequiel; Luchtefeld Maren; Drexler Helmut; Müller Werner; Grote Karsten; Schieffer Bernhard
Hepatocyte gp130 deficiency reduces vascular remodeling after carotid artery ligation.
Stehr Matthias; Greweling Marina C; Tischer Sabine; Singh Mahavir; Blöcker Helmut; Monner David A; Müller Werner
Charles River altered Schaedler flora (CRASF) remained stable for four years in a mouse colony housed in individually ventilated cages.
Schippers Angela; Leuker Christoph; Pabst Oliver; Kochut Annika; Prochnow Blair; Gruber Achim D; Leung Euphemia; Krissansen Geoffrey W; Wagner Norbert; Müller Werner
Mucosal addressin cell-adhesion molecule-1 controls plasma-cell migration and function in the small intestine of mice.

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2009: Salguero Gustavo; Schuett Harald; Jagielska Joanna; Schley René; Tallone Ezequiel; Luchtefeld Maren; Drexler Helmut; Müller Werner; Grote Karsten; Schieffer Bernhard
Hepatocyte gp130 deficiency reduces vascular remodeling after carotid artery ligation.
Hypertension 2009;54(5):1035-42.
2009: Stehr Matthias; Greweling Marina C; Tischer Sabine; Singh Mahavir; Blöcker Helmut; Monner David A; Müller Werner
Charles River altered Schaedler flora (CRASF) remained stable for four years in a mouse colony housed in individually ventilated cages.
Laboratory animals 2009;43(4):362-70.
2009: Schippers Angela; Leuker Christoph; Pabst Oliver; Kochut Annika; Prochnow Blair; Gruber Achim D; Leung Euphemia; Krissansen Geoffrey W; Wagner Norbert; Müller Werner
Mucosal addressin cell-adhesion molecule-1 controls plasma-cell migration and function in the small intestine of mice.
Gastroenterology 2009;137(3):924-33.
2009: Fasnacht Nicolas; Greweling Marina C; Bollati-Fogolín Mariela; Schippers Angela; Müller Werner
T-cell-specific deletion of gp130 renders the highly susceptible IL-10-deficient mouse resistant to intestinal nematode infection.
European journal of immunology 2009;39(8):2173-83.
2008: Waibler Zoe; Anzaghe Martina; Konur Abdo; Akira Shizuo; Müller Werner; Kalinke Ulrich
Excessive CpG 1668 stimulation triggers IL-10 production by cDC that inhibits IFN-alpha responses by pDC.
European journal of immunology 2008;38(11):3127-37.
2008: Frommer Friederike; Heinen Tobias J A J; Wunderlich F Thomas; Yogev Nir; Buch Thorsten; Roers Axel; Bettelli Estelle; Müller Werner; Anderton Stephen M; Waisman Ari
Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5748-59.
2008: Fasnacht Nicolas; Müller Werner
Conditional gp130 deficient mouse mutants.
Seminars in cell & developmental biology 2008;19(4):379-84.
2008: Drögemüller Katrin; Helmuth Ulrike; Brunn Anna; Sakowicz-Burkiewicz Monika; Gutmann David H; Mueller Werner; Deckert Martina; Schlüter Dirk
Astrocyte gp130 expression is critical for the control of Toxoplasma encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2683-93.
2008: Sanchez-Ruiz Monica; Wilden Laura; Müller Werner; Stenzel Werner; Brunn Anna; Miletic Hrvoje; Schlüter Dirk; Deckert Martina
Molecular mimicry between neurons and an intracerebral pathogen induces a CD8 T cell-mediated autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8421-33.
2008: Hömig-Hölzel Cornelia; Hojer Caroline; Rastelli Julia; Casola Stefano; Strobl Lothar J; Müller Werner; Quintanilla-Martinez Leticia; Gewies Andreas; Ruland Jürgen; Rajewsky Klaus; Zimber-Strobl Ursula
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.
The Journal of experimental medicine 2008;205(6):1317-29.
2008: Kida Hiroshi; Mucenski Michael L; Thitoff Angela R; Le Cras Timothy D; Park Kwon-Sik; Ikegami Machiko; Müller Werner; Whitsett Jeffrey A
GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium.
The American journal of pathology 2008;172(6):1542-54.
2008: Apostolaki Maria; Manoloukos Menelaos; Roulis Manolis; Wurbel Marc-André; Müller Werner; Papadakis Konstantinos A; Kontoyiannis Dimitris L; Malissen Bernard; Kollias George
Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.
Gastroenterology 2008;134(7):2025-35.
2008: Sudarman Enge; Bollati-Fogolín Mariela; Hafner Martin; Müller Werner; Scheller Jürgen; Rose-John Stefan; Eichler Jutta
Synthetic mimetics of the gp130 binding site for viral interleukin-6 as inhibitors of the vIL-6-gp130 interaction.
Chemical biology & drug design 2008;71(5):494-500.
2008: Schippers Angela; Mateika Silke; Prochnow Blair; Gruber Achim D; Müller Werner; Frischmann Ursula
Susceptibility of four inbred mouse strains to a low-pathogenic isolate of Yersinia enterocolitica.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(4):279-91.
2008: Rubtsov Yuri P; Rasmussen Jeffrey P; Chi Emil Y; Fontenot Jason; Castelli Luca; Ye Xin; Treuting Piper; Siewe Lisa; Roers Axel; Henderson William R; Muller Werner; Rudensky Alexander Y
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.
Immunity 2008;28(4):546-58.
2008: Scholten Julia; Hartmann Karin; Gerbaulet Alexander; Krieg Thomas; Müller Werner; Testa Giuseppe; Roers Axel
Mast cell-specific Cre/loxP-mediated recombination in vivo.
Transgenic research 2008;17(2):307-15.
2008: Berberich Simon; Dähne Sabrina; Schippers Angela; Peters Thorsten; Müller Werner; Kremmer Elisabeth; Förster Reinhold; Pabst Oliver
Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2196-203.
2008: Rastelli Julia; Hömig-Hölzel Cornelia; Seagal Jane; Müller Werner; Hermann Andrea C; Rajewsky Klaus; Zimber-Strobl Ursula
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1.
Blood 2008;111(3):1448-55.
2007: Czeloth Niklas; Schippers Angela; Wagner Norbert; Müller Werner; Küster Birgit; Bernhardt Günter; Förster Reinhold
Sphingosine-1 phosphate signaling regulates positioning of dendritic cells within the spleen.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5855-63.
2007: Retter Ida; Chevillard Christophe; Scharfe Maren; Conrad Ansgar; Hafner Martin; Im Tschong-Hun; Ludewig Monika; Nordsiek Gabriele; Severitt Simone; Thies Stephanie; Mauhar America; Blöcker Helmut; Müller Werner; Riblet Roy
Sequence and characterization of the Ig heavy chain constant and partial variable region of the mouse strain 129S1.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2419-27.
2007: Luchtefeld Maren; Schunkert Heribert; Stoll Monika; Selle Tina; Lorier Rachel; Grote Karsten; Sagebiel Christian; Jagavelu Kumaravelu; Tietge Uwe J F; Assmus Ulrike; Streetz Konrad; Hengstenberg Christian; Fischer Marcus; Mayer Björn; Maresso Karen; El Mokhtari Nour Eddine; Schreiber Stefan; Müller Werner; Bavendiek Udo; Grothusen Christina; Drexler Helmut; Trautwein Christian; Broeckel Ulrich; Schieffer Bernhard
Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man.
The Journal of experimental medicine 2007;204(8):1935-44.
2007: Maier Michael K; Seth Sebastian; Czeloth Niklas; Qiu Quan; Ravens Inga; Kremmer Elisabeth; Ebel Maria; Müller Werner; Pabst Oliver; Förster Reinhold; Bernhardt Günter
The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens.
European journal of immunology 2007;37(8):2214-25.
2007: Fleige Anne; Alberti Siegfried; Gröbe Lothar; Frischmann Ursula; Geffers Robert; Müller Werner; Nordheim Alfred; Schippers Angela
Serum response factor contributes selectively to lymphocyte development.
The Journal of biological chemistry 2007;282(33):24320-8.
2007: Hancock John M; Adams Niels C; Aidinis Vassilis; Blake Andrew; Bogue Molly; Brown Steve D M; Chesler Elissa J; Davidson Duncan; Duran Christopher; Eppig Janan T; Gailus-Durner Valérie; Gates Hilary; Gkoutos Georgios V; Greenaway Simon; Hrabé de Angelis Martin; Kollias George; Leblanc Sophie; Lee Kirsty; Lengger Christoph; Maier Holger; Mallon Ann-Marie; Masuya Hiroshi; Melvin David G; Müller Werner; Parkinson Helen; Proctor Glenn; Reuveni Eli; Schofield Paul; Shukla Aadya; Smith Cynthia; Toyoda Tetsuro; Vasseur Laurent; Wakana Shigeharu; Walling Alison; White Jacqui; Wood Joe; Zouberakis Michalis
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(3):157-63.
2006: Müller Werner
Dissecting the cytokine network.
Cellular immunology 2006;244(2):162-4.
2006: Siewe Lisa; Bollati-Fogolin Mariela; Wickenhauser Claudia; Krieg Thomas; Müller Werner; Roers Axel
Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA.
European journal of immunology 2006;36(12):3248-55.
2006: Lutz Johannes; Müller Werner; Jäck Hans-Martin
VH replacement rescues progenitor B cells with two nonproductive VDJ alleles.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7007-14.
2006: Harr B; Voolstra C; Heinen T J A J; Baines J F; Rottscheidt R; Ihle S; Müller W; Bonhomme F; Tautz D
A change of expression in the conserved signaling gene MKK7 is associated with a selective sweep in the western house mouse Mus musculus domesticus.
Journal of evolutionary biology 2006;19(5):1486-96.
2006: Peters Thorsten; Bloch Wilhelm; Wickenhauser Claudia; Tawadros Samir; Oreshkova Tsvetelina; Kess Daniel; Krieg Thomas; Müller Werner; Scharffetter-Kochanek Karin
Terminal B cell differentiation is skewed by deregulated interleukin-6 secretion in beta2 integrin-deficient mice.
Journal of leukocyte biology 2006;80(3):599-607.
2006: Janoschek Ruth; Plum Leona; Koch Linda; Münzberg Heike; Diano Sabrina; Shanabrough Marya; Müller Werner; Horvath Tamas L; Brüning Jens C
gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(28):10707-12.
2006: Frischmann Ursula; Müller Werner
Nine fluorescence parameter analysis on a four-color fluorescence activated flow cytometer.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(3):124-6.
2006: Pabst Oliver; Herbrand Heike; Willenzon Stefanie; Worbs Tim; Schippers Angela; Müller Werner; Bernhardt Günter; Förster Reinhold
Enhanced FTY720-mediated lymphocyte homing requires G alpha i signaling and depends on beta 2 and beta 7 integrin.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1474-80.
2005: Bollati-Fogolín Mariela; Müller Werner
Virus free, cell-based assay for the quantification of murine type I interferons.
Journal of immunological methods 2005;306(1-2):169-75.
2005: Strassburger Maria; Bloch Wilhelm; Sulyok Silke; Schüller Jutta; Keist Alexander F; Schmidt Annette; Wenk Jutta; Peters Thorsten; Wlaschek Meinhard; Lenart Jacek; Krieg Thomas; Hafner Martin; Kümin Angelika; Werner Sabine; Müller Werner; Scharffetter-Kochanek Karin
Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo.
Free radical biology & medicine 2005;38(11):1458-70.
2005: Retter Ida; Althaus Hans Helmar; Münch Richard; Müller Werner
VBASE2, an integrative V gene database.
Nucleic acids research 2005;33(Database issue):D671-4.
2004: Roers Axel; Siewe Lisa; Strittmatter Elke; Deckert Martina; Schlüter Dirk; Stenzel Werner; Gruber Achim D; Krieg Thomas; Rajewsky Klaus; Müller Werner
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation.
The Journal of experimental medicine 2004;200(10):1289-97.
2004: Vosshenrich Christian A J; Cumano Ana; Müller Werner; Di Santo James P; Vieira Paulo
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):11070-5.
2004: Hafner Martin; Wenk Jutta; Nenci Arianna; Pasparakis Manolis; Scharffetter-Kochanek Karin; Smyth Neil; Peters Thorsten; Kess Daniel; Holtkötter Olaf; Shephard Pierre; Kudlow Jeffrey E; Smola Hans; Haase Ingo; Schippers Angela; Krieg Thomas; Müller Werner
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein.
Genesis (New York, N.Y. : 2000) 2004;38(4):176-81.
2003: Kess Daniel; Peters Thorsten; Zamek Jan; Wickenhauser Claudia; Tawadros Samir; Loser Karin; Varga Georg; Grabbe Stephan; Nischt Roswitha; Sunderkötter Cord; Müller Werner; Krieg Thomas; Scharffetter-Kochanek Karin
CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5697-706.
2003: Streetz Konrad L; Wüstefeld Torsten; Klein Christian; Kallen Karl-Josef; Tronche Francois; Betz Ullrich A K; Schütz Günther; Manns Michael P; Müller Werner; Trautwein Christian
Lack of gp130 expression in hepatocytes promotes liver injury.
Gastroenterology 2003;125(2):532-43.
2003: Streetz Konrad L; Wüstefeld Torsten; Klein Christian; Kallen Karl-Josef; Tronche Francois; Betz Ullrich A K; Schütz Günther; Manns Michael P; Müller Werner; Trautwein Christian
Lack of gp130 expression in hepatocytes promotes liver injury.
Gastroenterology 2003;125(2):532-43.
2003: Fingerle-Rowson G; Petrenko O; Metz C N; Forsthuber T G; Mitchell R; Huss R; Moll U; Müller W; Bucala R
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9354-9.
2003: Vosshenrich Christian A J; Cumano Ana; Müller Werner; Di Santo James P; Vieira Paulo
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development.
Nature immunology 2003;4(8):773-9.
2003: Streetz Konrad L; Tacke Frank; Leifeld Ludger; Wüstefeld Torsten; Graw Andrea; Klein Christian; Kamino Kenjii; Spengler Ulrich; Kreipe Hans; Kubicka Stefan; Müller Werner; Manns Michael P; Trautwein Christian
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases.
Hepatology (Baltimore, Md.) 2003;38(1):218-29.
2003: Ranson Thomas; Vosshenrich Christian A J; Corcuff Erwan; Richard Odile; Müller Werner; Di Santo James P
IL-15 is an essential mediator of peripheral NK-cell homeostasis.
Blood 2003;101(12):4887-93.
2003: Deckert Martina; Lütjen Sonja; Leuker Christoph E; Kwok Lai-Yu; Strack Andreas; Müller Werner; Wagner Norbert; Schlüter Dirk
Mice with neonatally induced inactivation of the vascular cell adhesion molecule-1 fail to control the parasite in Toxoplasma encephalitis.
European journal of immunology 2003;33(5):1418-28.
2003: Wuestefeld Torsten; Klein Christian; Streetz Konrad L; Betz Ulrich; Lauber Jörg; Buer Jan; Manns Michael P; Müller Werner; Trautwein Christian
Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration.
The Journal of biological chemistry 2003;278(13):11281-8.
2003: Wuestefeld Torsten; Klein Christian; Streetz Konrad L; Betz Ulrich; Lauber Jörg; Buer Jan; Manns Michael P; Müller Werner; Trautwein Christian
Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration.
The Journal of biological chemistry 2003;278(13):11281-8.
2002: Kellersmann Richard; Lazarovits Andrew; Grant David; Garcia Bertha; Chan Bosco; Kellersmann Anne; Wang Hao; Jevnikar Anthony; Wagner Norbert; Müller Werner; Ulrichs Karin; Thiede Arnulf; Zhong Robert
Monoclonal antibody against beta7 integrins, but not beta7 deficiency, attenuates intestinal allograft rejection in mice.
Transplantation 2002;74(9):1327-34.
2002: Kellersmann Richard; Lazarovits Andrew; Grant David; Garcia Bertha; Chan Bosco; Kellersmann Anne; Wang Hao; Jevnikar Anthony; Wagner Norbert; Müller Werner; Ulrichs Karin; Thiede Arnulf; Zhong Robert
Monoclonal antibody against beta7 integrins, but not beta7 deficiency, attenuates intestinal allograft rejection in mice.
Transplantation 2002;74(9):1327-34.
2002: Sun Xueying; Qiao Haiquan; Shi Jinyang; Kanwar Jagat R; Mueller Werner; Wagner Norbert; Krissansen Geoffrey W
Beta7 integrins contribute to skin graft rejection.
Transplantation 2002;74(8):1202-3.
2002: Sun Xueying; Qiao Haiquan; Shi Jinyang; Kanwar Jagat R; Mueller Werner; Wagner Norbert; Krissansen Geoffrey W
Beta7 integrins contribute to skin graft rejection.
Transplantation 2002;74(8):1202-3.
2002: Sydora B C; Wagner N; Lohler J; Yakoub G; Kronenberg M; Muller W; Aranda R
beta7 Integrin expression is not required for the localization of T cells to the intestine and colitis pathogenesis.
Clinical and experimental immunology 2002;129(1):35-42.
2002: Holtkötter Olaf; Nieswandt Bernhard; Smyth Neil; Müller Werner; Hafner Martin; Schulte Valerie; Krieg Thomas; Eckes Beate
Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen.
The Journal of biological chemistry 2002;277(13):10789-94.
2001: Alonzi T; Middleton G; Wyatt S; Buchman V; Betz U A; Müller W; Musiani P; Poli V; Davies A M
Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons.
Molecular and cellular neurosciences 2001;18(3):270-82.
2001: Leuker C E; Labow M; Müller W; Wagner N
Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response.
The Journal of experimental medicine 2001;193(6):755-68.
2001: Leuker C E; Labow M; Müller W; Wagner N
Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response.
The Journal of experimental medicine 2001;193(6):755-68.
2001: Kuklin N A; Rott L; Feng N; Conner M E; Wagner N; Müller W; Greenberg H B
Protective intestinal anti-rotavirus B cell immunity is dependent on alpha 4 beta 7 integrin expression but does not require IgA antibody production.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1894-902.
2001: Kuklin N A; Rott L; Feng N; Conner M E; Wagner N; Müller W; Greenberg H B
Protective intestinal anti-rotavirus B cell immunity is dependent on alpha 4 beta 7 integrin expression but does not require IgA antibody production.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1894-902.
2000: Kuklin N A; Rott L; Darling J; Campbell J J; Franco M; Feng N; Müller W; Wagner N; Altman J; Butcher E C; Greenberg H B
alpha(4)beta(7) independent pathway for CD8(+) T cell-mediated intestinal immunity to rotavirus.
The Journal of clinical investigation 2000;106(12):1541-52.
2000: Kuklin N A; Rott L; Darling J; Campbell J J; Franco M; Feng N; Müller W; Wagner N; Altman J; Butcher E C; Greenberg H B
alpha(4)beta(7) independent pathway for CD8(+) T cell-mediated intestinal immunity to rotavirus.
The Journal of clinical investigation 2000;106(12):1541-52.
2000: Kellersmann R; Zhong R; Grant D; Garcia B; Blömer A; Liu W; Wagner N; Müller W; Jevnikar A; Thiede A; Lazarovits A
Despite high levels of lymphocyte homing receptor alpha4beta7 integrin after small bowel allotransplantation, it is not critical for rejection.
Transplantation proceedings 2000;32(6):1267-8.
2000: Sarnacki S; Auber F; Crétolle C; Camby C; Cavazzana-Calvo M; Müller W; Wagner N; Brousse N; Révillon Y; Fischer A; Cerf-Bensussan N
Blockade of the integrin alphaLbeta2 but not of integrins alpha4 and/or beta7 significantly prolongs intestinal allograft survival in mice.
Gut 2000;47(1):97-104.
2000: Artis D; Humphreys N E; Potten C S; Wagner N; Müller W; McDermott J R; Grencis R K; Else K J
Beta7 integrin-deficient mice: delayed leukocyte recruitment and attenuated protective immunity in the small intestine during enteric helminth infection.
European journal of immunology 2000;30(6):1656-64.
2000: Vosshenrich C A; Sharara L I; Guy-Grand D; Rajewsky K; Müller W; Di Santo J P
Common cytokine receptor gamma chain (gammac)-deficient B cells persist in T cell-deficient gammac-mice and respond to a T-independent antigen.
European journal of immunology 2000;30(6):1614-22.
2000: Kanwar J R; Harrison J E; Wang D; Leung E; Mueller W; Wagner N; Krissansen G W
Beta7 integrins contribute to demyelinating disease of the central nervous system.
Journal of neuroimmunology 2000;103(2):146-52.
2000: Kanwar J R; Harrison J E; Wang D; Leung E; Mueller W; Wagner N; Krissansen G W
Beta7 integrins contribute to demyelinating disease of the central nervous system.
Journal of neuroimmunology 2000;103(2):146-52.
2000: Esposito G; Texido G; Betz U A; Gu H; Müller W; Klein U; Rajewsky K
Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1166-71.
1999: Lefrançois L; Parker C M; Olson S; Muller W; Wagner N; Schön M P; Puddington L
The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response.
The Journal of experimental medicine 1999;189(10):1631-8.
1999: Hirota H; Chen J; Betz U A; Rajewsky K; Gu Y; Ross J; Müller W; Chien K R
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress.
Cell 1999;97(2):189-98.
1999: Novobrantseva T I; Martin V M; Pelanda R; Müller W; Rajewsky K; Ehlich A
Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice.
The Journal of experimental medicine 1999;189(1):75-88.
1999: Lefranc M P; Giudicelli V; Ginestoux C; Bodmer J; Müller W; Bontrop R; Lemaitre M; Malik A; Barbié V; Chaume D
IMGT, the international ImMunoGeneTics database.
Nucleic acids research 1999;27(1):209-12.
1998: Steeber D A; Tang M L; Zhang X Q; Müller W; Wagner N; Tedder T F
Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6638-47.
1998: Steeber D A; Tang M L; Zhang X Q; Müller W; Wagner N; Tedder T F
Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6638-47.
1998: Wagner N; Löhler J; Tedder T F; Rajewsky K; Müller W; Steeber D A
L-selectin and beta7 integrin synergistically mediate lymphocyte migration to mesenteric lymph nodes.
European journal of immunology 1998;28(11):3832-9.
1998: Betz U A; Bloch W; van den Broek M; Yoshida K; Taga T; Kishimoto T; Addicks K; Rajewsky K; Müller W
Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects.
The Journal of experimental medicine 1998;188(10):1955-65.
1998: Kunkel E J; Ramos C L; Steeber D A; Müller W; Wagner N; Tedder T F; Ley K
The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2449-56.
1998: Kunkel E J; Ramos C L; Steeber D A; Müller W; Wagner N; Tedder T F; Ley K
The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2449-56.
1998: Betz U A; Müller W
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation.
International immunology 1998;10(8):1175-84.
1998: Wynn T A; Cheever A W; Williams M E; Hieny S; Caspar P; Kühn R; Müller W; Sher A
IL-10 regulates liver pathology in acute murine Schistosomiasis mansoni but is not required for immune down-modulation of chronic disease.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4473-80.
1998: Lefranc M P; Giudicelli V; Busin C; Bodmer J; Müller W; Bontrop R; Lemaitre M; Malik A; Chaume D
IMGT, the International ImMunoGeneTics database.
Nucleic acids research 1998;26(1):297-303.
1998: Giudicelli V; Chaume D; Mennessier G; Althaus H H; Müller W; Bodmer J; Malik A; Lefranc M P
IMGT, the international ImMunoGeneTics database: a new design for immunogenetics data access.
Studies in health technology and informatics 1998;52 Pt 1():351-5.
1998: Wagner N; Müller W
Functions of alpha 4- and beta 7-integrins in hematopoiesis, lymphocyte trafficking and organ development.
Current topics in microbiology and immunology 1998;231():23-32.
1997: Wynn T A; Morawetz R; Scharton-Kersten T; Hieny S; Morse H C; Kühn R; Müller W; Cheever A W; Sher A
Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):5014-23.
1997: Sharara L I; Vosshenrich C A; Müller W; DiSanto J P
On the role of the common cytokine receptor gamma chain in B-cell vs. T-cell development.
Research in immunology 1997;148(7):449-53.
1997: Kühn R; Müller W
Gene targeting in immunology.
Research in immunology 1997;148(7):447-9.
1997: Schwenk F; Sauer B; Kukoc N; Hoess R; Müller W; Kocks C; Kühn R; Rajewsky K
Generation of Cre recombinase-specific monoclonal antibodies, able to characterize the pattern of Cre expression in cre-transgenic mouse strains.
Journal of immunological methods 1997;207(2):203-12.
1997: Giudicelli V; Chaume D; Bodmer J; Müller W; Busin C; Marsh S; Bontrop R; Marc L; Malik A; Lefranc M P
IMGT, the international ImMunoGeneTics database.
Nucleic acids research 1997;25(1):206-11.
1997: Santiago M L; Fossati L; Jacquet C; Müller W; Izui S; Reininger L
Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome.
The Journal of experimental medicine 1997;185(1):65-70.
1996: Linke A; Kühn R; Müller W; Honarvar N; Li C; Langhorne J
Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection.
Experimental parasitology 1996;84(2):253-63.
1996: Morawetz R A; Gabriele L; Rizzo L V; Noben-Trauth N; Kühn R; Rajewsky K; Müller W; Doherty T M; Finkelman F; Coffman R L; Morse H C
Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.
The Journal of experimental medicine 1996;184(5):1651-61.
1996: Betz U A; Vosshenrich C A; Rajewsky K; Müller W
Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination.
Current biology : CB 1996;6(10):1307-16.
1996: Beissert S; Hosoi J; Kühn R; Rajewsky K; Müller W; Granstein R D
Impaired immunosuppressive response to ultraviolet radiation in interleukin-10-deficient mice.
The Journal of investigative dermatology 1996;107(4):553-7.
1996: Berg D J; Davidson N; Kühn R; Müller W; Menon S; Holland G; Thompson-Snipes L; Leach M W; Rennick D
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.
The Journal of clinical investigation 1996;98(4):1010-20.
1996: Texidó G; Jacobs H; Meiering M; Kühn R; Roes J; Müller W; Gilfillan S; Fujiwara H; Kikutani H; Yoshida N; Amakawa R; Benoist C; Mathis D; Kishimoto T; Mak T W; Rajewsky K
Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants.
European journal of immunology 1996;26(8):1966-9.
1996: Rajewsky K; Gu H; Kühn R; Betz U A; Müller W; Roes J; Schwenk F
Conditional gene targeting.
The Journal of clinical investigation 1996;98(3):600-3.
1996: Gazzinelli R T; Wysocka M; Hieny S; Scharton-Kersten T; Cheever A; Kühn R; Müller W; Trinchieri G; Sher A
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):798-805.
1996: Davidson N J; Leach M W; Fort M M; Thompson-Snipes L; Kühn R; Müller W; Berg D J; Rennick D M
T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
The Journal of experimental medicine 1996;184(1):241-51.
1996: Wagner N; Löhler J; Kunkel E J; Ley K; Leung E; Krissansen G; Rajewsky K; Müller W
Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue.
Nature 1996;382(6589):366-70.
1996: Wagner N; Löhler J; Kunkel E J; Ley K; Leung E; Krissansen G; Rajewsky K; Müller W
Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue.
Nature 1996;382(6589):366-70.
1996: Löffert D; Ehlich A; Müller W; Rajewsky K
Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development.
Immunity 1996;4(2):133-44.
1995: Di Santo J P; Kühn R; Müller W
Common cytokine receptor gamma chain (gamma c)-dependent cytokines: understanding in vivo functions by gene targeting.
Immunological reviews 1995;148():19-34.
1995: Berg D J; Kühn R; Rajewsky K; Müller W; Menon S; Davidson N; Grünig G; Rennick D
Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.
The Journal of clinical investigation 1995;96(5):2339-47.
1995: Bachmann M F; Schorle H; Kühn R; Müller W; Hengartner H; Zinkernagel R M; Horak I
Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4.
Journal of virology 1995;69(8):4842-6.
1995: Berg D J; Leach M W; Kühn R; Rajewsky K; Müller W; Davidson N J; Rennick D
Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.
The Journal of experimental medicine 1995;182(1):99-108.
1995: Tarakhovsky A; Kanner S B; Hombach J; Ledbetter J A; Müller W; Killeen N; Rajewsky K
A role for CD5 in TCR-mediated signal transduction and thymocyte selection.
Science (New York, N.Y.) 1995;269(5223):535-7.
1995: Roes J; Müller W; Rajewsky K
Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice.
Journal of immunological methods 1995;183(2):231-7.
1995: Wei X Q; Charles I G; Smith A; Ure J; Feng G J; Huang F P; Xu D; Muller W; Moncada S; Liew F Y
Altered immune responses in mice lacking inducible nitric oxide synthase.
Nature 1995;375(6530):408-11.
1994: Zou Y R; Müller W; Gu H; Rajewsky K
Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies.
Current biology : CB 1994;4(12):1099-103.
1994: Schmitt E; Germann T; Goedert S; Hoehn P; Huels C; Koelsch S; Kühn R; Müller W; Palm N; Rüde E
IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):3989-96.
1994: Morawetz R A; Doherty T M; Giese N A; Hartley J W; Müller W; Kühn R; Rajewsky K; Coffman R; Morse H C
Resistance to murine acquired immunodeficiency syndrome (MAIDS)
Science (New York, N.Y.) 1994;265(5169):264-6; author reply 267.
1994: Ehlich A; Martin V; Müller W; Rajewsky K
Analysis of the B-cell progenitor compartment at the level of single cells.
Current biology : CB 1994;4(7):573-83.
1994: Tarakhovsky A; Müller W; Rajewsky K
Lymphocyte populations and immune responses in CD5-deficient mice.
European journal of immunology 1994;24(7):1678-84.
1994: Schmitz J; Thiel A; Kühn R; Rajewsky K; Müller W; Assenmacher M; Radbruch A
Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells.
The Journal of experimental medicine 1994;179(4):1349-53.
1994: Löffert D; Schaal S; Ehlich A; Hardy R R; Zou Y R; Müller W; Rajewsky K
Early B-cell development in the mouse: insights from mutations introduced by gene targeting.
Immunological reviews 1994;137():135-53.
1994: Sadlack B; Kühn R; Schorle H; Rajewsky K; Müller W; Horak I
Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4.
European journal of immunology 1994;24(1):281-4.
1993: Kühn R; Löhler J; Rennick D; Rajewsky K; Müller W
Interleukin-10-deficient mice develop chronic enterocolitis.
Cell 1993;75(2):263-74.
1993: Müller W; Rajewsky K; Kühn R
Interleukin-4-deficient mice.
Research in immunology 1993;144(8):637-8.
1993: Ehlich A; Schaal S; Gu H; Kitamura D; Müller W; Rajewsky K
Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development.
Cell 1993;72(5):695-704.
1993: Leal L M; Moss D W; Kuhn R; Müller W; Liew F Y
Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection.
European journal of immunology 1993;23(2):566-9.
1992: Schultz C L; Rothman P; Kühn R; Kehry M; Müller W; Rajewsky K; Alt F; Coffman R L
T helper cell membranes promote IL-4-independent expression of germ-line C gamma 1 transcripts in B cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(1):60-4.
1992: Kitamura D; Kudo A; Schaal S; Müller W; Melchers F; Rajewsky K
A critical role of lambda 5 protein in B cell development.
Cell 1992;69(5):823-31.
1992: Platzer C; Richter G; Uberla K; Müller W; Blöcker H; Diamantstein T; Blankenstein T
Analysis of cytokine mRNA levels in interleukin-4-transgenic mice by quantitative polymerase chain reaction.
European journal of immunology 1992;22(5):1179-84.
1992: Platzer C; Richter G; Uberla K; Müller W; Blöcker H; Diamantstein T; Blankenstein T
Analysis of cytokine mRNA levels in interleukin-4-transgenic mice by quantitative polymerase chain reaction.
European journal of immunology 1992;22(5):1179-84.
1991: Kühn R; Rajewsky K; Müller W
Generation and analysis of interleukin-4 deficient mice.
Science (New York, N.Y.) 1991;254(5032):707-10.
1991: Förster I; Müller W; Schittek B; Rajewsky K
Generation of long-lived B cells in germ-free mice.
European journal of immunology 1991;21(7):1779-82.
1991: Gu H; Tarlinton D; Müller W; Rajewsky K; Förster I
Most peripheral B cells in mice are ligand selected.
The Journal of experimental medicine 1991;173(6):1357-71.
1991: Blankenstein T; Qin Z H; Uberla K; Müller W; Rosen H; Volk H D; Diamantstein T
Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer.
The Journal of experimental medicine 1991;173(5):1047-52.
1991: Blankenstein T; Qin Z H; Uberla K; Müller W; Rosen H; Volk H D; Diamantstein T
Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer.
The Journal of experimental medicine 1991;173(5):1047-52.
1991: Müller W; Kühn R; Rajewsky K
Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia.
European journal of immunology 1991;21(4):921-5.
1991: Förster I; Gu H; Müller W; Schmitt M; Tarlinton D; Rajewsky K
CD5 B cells in the mouse.
Current topics in microbiology and immunology 1991;173():247-51.
1990: Blankenstein T; Li W Q; Müller W; Diamantstein T
Retroviral interleukin 4 gene transfer into an interleukin 4-dependent cell line results in autocrine growth but not in tumorigenicity.
European journal of immunology 1990;20(4):935-8.
1990: Blankenstein T; Li W Q; Müller W; Diamantstein T
Retroviral interleukin 4 gene transfer into an interleukin 4-dependent cell line results in autocrine growth but not in tumorigenicity.
European journal of immunology 1990;20(4):935-8.
1990: Miltenyi S; Müller W; Weichel W; Radbruch A
High gradient magnetic cell separation with MACS.
Cytometry 1990;11(2):231-8.
1989: Müller W; Rüther U; Vieira P; Hombach J; Reth M; Rajewsky K
Membrane-bound IgM obstructs B cell development in transgenic mice.
European journal of immunology 1989;19(5):923-8.
1988: Blankenstein T; Winter E; Müller W
A retroviral expression vector containing murine immunoglobulin heavy chain promoter/enhancer.
Nucleic acids research 1988;16(22):10939.
1988: Rüther U; Müller W; Sumida T; Tokuhisa T; Rajewsky K; Wagner E F
c-fos expression interferes with thymus development in transgenic mice.
Cell 1988;53(6):847-56.
1986: Radbruch A; Müller W; Rajewsky K
Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):3954-7.
1986: Göttlinger C; Meyer K L; Weichel W; Müller W; Raftery B; Radbruch A
Cell-cooling in flow cytometry by Peltier elements.
Cytometry 1986;7(3):295-7.
1986: Radbruch A; Burger C; Klein S; Müller W
Control of immunoglobulin class switch recombination.
Immunological reviews 1986;89():69-83.
1985: Müller W; Kühn R; Goldmann W; Tesch H; Smith F I; Radbruch A; Rajewsky K
Signal requirements for growth and differentiation of activated murine B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(2):1213-9.

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