FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Sandro Cosconati

Research Profile

Concepts & Ideas

Chemicals & Drugs

Phenomena

Protein Binding

Procedures

Living Beings

Co-author Network

Publications

TOP 3
Sergio Valente; Lucia Altucci; Rosaria Benedetti; Roberto Boggio; Donatella Del Bufalo; Salvatore Di Maro; Donatella Labella; Antonello Mai; Ciro Mercurio; Ettore Novellino; Daniela Secci; Maria Tardugno; Stefano Tomassi; Daniela Trisciuoglio; Sandro Cosconati
tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells.
Vittorio Limongelli; Claudio Luchinat; Luciana Marinelli; Ettore Novellino; Bruno Pagano; Ivano Bertini; Linda Cerofolini; Sandro Cosconati; Stefano De Tito; Marco Fragai; Antonio Randazzo; Roberta Trotta; Michele Parrinello
The G-triplex DNA.
Angela De Simone; Valeria La Pietra; Francesca Mancini; Luciana Marinelli; Ettore Novellino; Sandro Cosconati; Vincenza Andrisano
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Sandro Cosconati (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Sergio Valente; Lucia Altucci; Rosaria Benedetti; Roberto Boggio; Donatella Del Bufalo; Salvatore Di Maro; Donatella Labella; Antonello Mai; Ciro Mercurio; Ettore Novellino; Daniela Secci; Maria Tardugno; Stefano Tomassi; Daniela Trisciuoglio; Sandro Cosconati
tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells.
ChemMedChem 2013;8(5):800-11.
2013: Vittorio Limongelli; Claudio Luchinat; Luciana Marinelli; Ettore Novellino; Bruno Pagano; Ivano Bertini; Linda Cerofolini; Sandro Cosconati; Stefano De Tito; Marco Fragai; Antonio Randazzo; Roberta Trotta; Michele Parrinello
The G-triplex DNA.
Angewandte Chemie (International ed. in English) 2013;52(8):2269-73.
2013: Angela De Simone; Valeria La Pietra; Francesca Mancini; Luciana Marinelli; Ettore Novellino; Sandro Cosconati; Vincenza Andrisano
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library.
Journal of pharmaceutical and biomedical analysis 2013;73():131-4.
2012: Stefania Sartini; Francesca Simorini; Sabrina Taliani; Elisabetta Barresi; Sandro Cosconati; Federico Da Settimo; Salvatore Di Maro; Luciana Marinelli; Anna Maria Marini; Ettore Novellino; Silvia Salerno; Concettina La Motta
Benzofuroxane derivatives as multi-effective agents for the treatment of cardiovascular diabetic complications. Synthesis, functional evaluation, and molecular modeling studies.
Journal of medicinal chemistry 2012;55(23):10523-31.
2012: Sandro Cosconati; Stefano De Tito; Iolanda Fotticchia; Concetta Giancola; Mariateresa Giustiniano; Sara Iachettini; Ilaria Lauri; Luciana Marinelli; Ettore Novellino; Bruno Pagano; Angela Rizzo; Roberta Trotta; Annamaria Biroccio; Antonio Randazzo
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.
Journal of medicinal chemistry 2012;55(22):9785-92.
2012: Sandro Cosconati; Angela De Simone; Francesco Saverio Di Leva; David S Goodsell; Valeria La Pietra; Francesca Mancini; Luciana Marinelli; Ettore Novellino; Vincenza Andrisano; Arthur J Olson
Protein flexibility in virtual screening: the BACE-1 case study.
Journal of chemical information and modeling 2012;52(10):2697-704.
2012: Lucia Tamborini; Pui E Wong; Michael P Barrett; Sandro Cosconati; Carlo De Micheli; Maria C Iannuzzi; Leonardo Lo Presti; Louise L Major; Luciana Marinelli; Ettore Novellino; Andrea Pinto; Terry K Smith; Paola Conti
Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
ChemMedChem 2012;7(9):1623-34.
2012: Oliver Demmer; Andreas O Frank; Franz Hagn; Stephan Kremb; Luciana Marinelli; Margret Schottelius; Hans-Jürgen Wester; Ruth Brack-Werner; Sandro Cosconati; Horst Kessler
A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity.
Angewandte Chemie (International ed. in English) 2012;51(32):8110-3.
2012: Giuseppe La Regina; giovanni maga; Ettore Novellino; Francesco Piscitelli; Alberta Samuele; Dominique Schols; Andrea Brancale; Bonaventura Clotet; Antonio Coluccia; Sandro Cosconati; José A Esté; Valeria Famiglini; Emmanuel Gonzalez; Romano Silvestri
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal of medicinal chemistry 2012;55(14):6634-8.
2012: Pier Giovanni Baraldi; Stefania Baraldi; Pier Andrea Borea; Sandro Cosconati; Salvatore Di Maro; Stefania Gessi; Luciana Marinelli; Stefania Merighi; Allan R Moorman; Romeo Romagnoli; Giulia Saponaro; Katia Varani; Mojgan Aghazadeh Tabrizi; Delia Preti
Water-soluble pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as human A₃ adenosine receptor antagonists.
Journal of medicinal chemistry 2012;55(11):5380-90.
2012: Sabrina Castellano; Sandro Cosconati; Barbara Costa; Eleonora Da Pozzo; Sara Bendinelli; Giovanni Greco; Claudia Martini; Ciro Milite; Ettore Novellino; Isabella Pugliesi; Elisa Rizzetto; Gianluca Sbardella; Giorgio Stefancich; Sabrina Taliani; Federico Da Settimo
Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein.
Journal of medicinal chemistry 2012;55(9):4506-10.
2012: Anna Ramunno; Stefania Sartini; Sara Angiuoli; Sandro Cosconati; Federico Da Settimo; Salvatore Di Maro; Mariateresa Giustiniano; Concettina La Motta; Valeria La Pietra; Vita Maglio; Luciana Marinelli; Ettore Novellino
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step.
European journal of medicinal chemistry 2012;51():216-26.
2012: Sabrina Taliani; Maria Letizia Trincavelli; Elisabetta Barresi; Sandro Cosconati; Barbara Cosimelli; Simona Daniele; Salvatore Di Maro; Giovanni Greco; Concettina La Motta; Luciana Marinelli; Anna Maria Marini; Claudia Martini; Ettore Novellino; Isabella Pugliesi; Silvia Salerno; Francesca Simorini; Federico Da Settimo
3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.
Journal of medicinal chemistry 2012;55(4):1490-9.
2012: Vittorio Limongelli; Luciana Marinelli; Laura Mugnaini; Ettore Novellino; Sandro Cosconati; Federico Da Settimo; Concettina La Motta; Stefania Sartini; Michele Parrinello
Sampling protein motion and solvent effect during ligand binding.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(5):1467-72.
2012: Bruno Pagano; Luigi Petraccone; Roberta Trotta; Sandro Cosconati; Stefano De Tito; Francesco Saverio di Leva; Valérie Gabelica; Concetta Giancola; Valeria La Pietra; Ilaria Lauri; Luciana Marinelli; Ettore Novellino; Antonio Randazzo
State-of-the-art methodologies for the discovery and characterization of DNA G-quadruplex binders.
Current pharmaceutical design 2012;18(14):1880-99.
2012: Barbara Cosimelli; Luciana Marinelli; Ettore Novellino; Sandro Cosconati; Giovanni Greco
From the pharmacophore to the homology model of the benzodiazepine receptor: the indolyglyoxylamides affair.
Current topics in medicinal chemistry 2012;12(4):321-32.
2012: Valeria La Pietra; Concettina La Motta; Luciana Marinelli; Matteo Morelli; Hideaki Nagase; Francesca Casalini; Sandro Cosconati; Federico Da Settimo; Francesco Saverio Di Leva; Elisa Nuti; Isabella Pugliesi; Armando Rossello; Salvatore Santamaria; Sabrina Taliani; Robert Visse; Ettore Novellino
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: a first round of lead optimization.
European journal of medicinal chemistry 2012;47(1):143-52.
2011: Oliver Demmer; Ingrid Dijkgraaf; Eleni Gourni; Luciana Marinelli; Udo Schumacher; Hans-Jürgen Wester; Sandro Cosconati; Horst Kessler
Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4.
Journal of medicinal chemistry 2011;54(21):7648-62.
2011: Carlos Mas-Moruno; Ettore Novellino; Luciana Marinelli; Johannes G Beck; Sandro Cosconati; Lucas Doedens; Andreas O Frank; Horst Kessler
Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.
Angewandte Chemie (International ed. in English) 2011;50(40):9496-500.
2011: Alessia Scatena; Sabrina Taliani; Maria Letizia Trincavelli; Sandro Cosconati; Simona Daniele; Francesco Fornai; Claudia Martini; Isabella Pugliesi; Federico Da Settimo
3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a novel adenosine receptor antagonist with A(2A)-mediated neuroprotective effects.
ACS chemical neuroscience 2011;2(9):526-35.
2011: Roberta Trotta; Maria R Conte; Sandro Cosconati; Stefano De Tito; Valeria La Pietra; Ilaria Lauri; Luciana Marinelli; Luigi Martino; Luciano Mayol; Ettore Novellino; Antonio Randazzo
A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies.
Biochimie 2011;93(8):1280-7.
2011: Pier Giovanni Baraldi; Stefania Baraldi; Sandro Cosconati; Salvatore Di Maro; Luciana Marinelli; Allan R Moorman; Ettore Novellino; Delia Preti; LUISA-CARLOTA LÓPEZ-CARA; Giulia Saponaro; Mojgan Aghazadeh Tabrizi; Katia Varani; Abdel Naser Zaid; Pier Andrea Borea
New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Journal of medicinal chemistry 2011;54(14):5205-20.
2011: Rosaria Ottanà; Rosanna Maccari; Marco Giglio; Antonella Del Corso; Mario Cappiello; Umberto Mura; Sandro Cosconati; Luciana Marinelli; Ettore Novellino; Stefania Sartini; Concettina La Motta; Federico Da Settimo
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications.
European journal of medicinal chemistry 2011;46(7):2797-806.
2011: Guido Bocci; Anna Fioravanti; Concettina La Motta; Paola Orlandi; Bastianina Canu; Teresa Di Desidero; Laura Mugnaini; Stefania Sartini; Sandro Cosconati; Rita Frati; Alessandro Antonelli; Piero Berti; Paolo Miccoli; Federico Da Settimo; Romano Danesi
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells.
Biochemical pharmacology 2011;81(11):1309-16.
2010: Andreas O Frank; Elke Otto; Carlos Mas-Moruno; Herbert B Schiller; Luciana Marinelli; Sandro Cosconati; Alexander Bochen; Dörte Vossmeyer; Grit Zahn; Roland Stragies; Ettore Novellino; Horst Kessler
Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch.
Angewandte Chemie (International ed. in English) 2010;49(48):9278-81.
2010: Sabrina Taliani; Concettina La Motta; Laura Mugnaini; Francesca Simorini; Silvia Salerno; Anna Maria Marini; Federico Da Settimo; Sandro Cosconati; Barbara Cosimelli; Giovanni Greco; Vittorio Limongelli; Luciana Marinelli; Ettore Novellino; Osele Ciampi; Simona Daniele; Maria Letizia Trincavelli; Claudia Martini
Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation.
Journal of medicinal chemistry 2010;53(10):3954-63.
2010: Sandro Cosconati; Luciana Marinelli; Roberta Trotta; Ada Virno; Stefano De Tito; Romeo Romagnoli; Bruno Pagano; Vittorio Limongelli; Concetta Giancola; Pier Giovanni Baraldi; Luciano Mayol; Ettore Novellino; Antonio Randazzo
Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.
Journal of the American Chemical Society 2010;132(18):6425-33.
2009: Sandro Cosconati; Luciana Marinelli; Roberta Trotta; Ada Virno; Luciano Mayol; Ettore Novellino; Arthur J Olson; Antonio Randazzo
Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.
Journal of the American Chemical Society 2009;131(45):16336-7.
2009: Sandro Cosconati; Luciana Marinelli; Concettina La Motta; Stefania Sartini; Federico Da Settimo; Arthur J Olson; Ettore Novellino
Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening.
Journal of medicinal chemistry 2009;52(18):5578-81.
2009: Sabrina Taliani; Barbara Cosimelli; Federico Da Settimo; Anna Maria Marini; Concettina La Motta; Francesca Simorini; Silvia Salerno; Ettore Novellino; Giovanni Greco; Sandro Cosconati; Luciana Marinelli; F Salvetti; Gianluca L'Abbate; Silvia Trasciatti; Marina Montali; Barbara Costa; Claudia Martini
Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor.
Journal of medicinal chemistry 2009;52(12):3723-34.
2009: Stefania Butini; Margherita Brindisi; Sandro Cosconati; Luciana Marinelli; Giuseppe Borrelli; Salvatore Sanna Coccone; Anna Ramunno; Giuseppe Campiani; Ettore Novellino; Samantha Zanoli; Alberta Samuele; Gianluca Giorgi; Alberto Bergamini; Michela Di Mattia; Silvana Lalli; Bruno Galletti; Sandra Gemma; giovanni maga
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations.
Journal of medicinal chemistry 2009;52(4):1224-8.
2008: Sandro Cosconati; Jiyoung A Hong; Ettore Novellino; Kate S Carroll; David S Goodsell; Arthur J Olson
Structure-based virtual screening and biological evaluation of Mycobacterium tuberculosis adenosine 5'-phosphosulfate reductase inhibitors.
Journal of medicinal chemistry 2008;51(21):6627-30.
2008: Roberta Budriesi; Pierfranco Ioan; Alessandra Locatelli; Sandro Cosconati; Alberto Leoni; Maria Paola Ugenti; Aldo Andreani; Rosanna Di Toro; Andrea Bedini; santi spampinato; Luciana Marinelli; Ettore Novellino; Alberto Chiarini
Imidazo[2,1-b]thiazole system: a scaffold endowing dihydropyridines with selective cardiodepressant activity.
Journal of medicinal chemistry 2008;51(6):1592-600.
2007: Luciana Marinelli; Sandro Cosconati; Thomas Steinbrecher; Vittorio Limongelli; Alessia Bertamino; Ettore Novellino; David A Case
Homology modeling of NR2B modulatory domain of NMDA receptor and analysis of ifenprodil binding.
ChemMedChem 2007;2(10):1498-510.
2007: Vittorio Limongelli; Luciana Marinelli; Sandro Cosconati; Hannes A Braun; Boris Schmidt; Ettore Novellino
Ensemble-docking approach on BACE-1: pharmacophore perception and guidelines for drug design.
ChemMedChem 2007;2(5):667-78.
2007: Sandro Cosconati; Luciana Marinelli; Antonio Lavecchia; Ettore Novellino
Characterizing the 1,4-dihydropyridines binding interactions in the L-type Ca2+ channel: model construction and docking calculations.
Journal of medicinal chemistry 2007;50(7):1504-13.
2007: Antonio Lavecchia; Sandro Cosconati; Ettore Novellino; Enrica Calleri; Caterina Temporini; Gabriella Massolini; Giuseppe Carbonara; Giuseppe Fracchiolla; Fulvio Loiodice
Exploring the molecular basis of the enantioselective binding of penicillin G acylase towards a series of 2-aryloxyalkanoic acids: a docking and molecular dynamics study.
Journal of molecular graphics & modelling 2007;25(6):773-83.
2006: Gabriella Massolini; Giuseppe Fracchiolla; Enrica Calleri; Giuseppe Carbonara; Caterina Temporini; Antonio Lavecchia; Sandro Cosconati; Ettore Novellino; Fulvio Loiodice
Elucidation of the enantioselective recognition mechanism of a penicillin G acylase-based chiral stationary phase towards a series of 2-aryloxy-2-arylacetic acids.
Chirality 2006;18(8):633-43.
2006: Antonio Lavecchia; Sandro Cosconati; Vittorio Limongelli; Ettore Novellino
Modeling of Cdc25B dual specifity protein phosphatase inhibitors: docking of ligands and enzymatic inhibition mechanism.
ChemMedChem 2006;1(5):540-50.
2005: Antonio Lavecchia; Sandro Cosconati; Ettore Novellino
Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists.
Journal of medicinal chemistry 2005;48(7):2480-92.