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Kim Theilgaard-Mönch

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Oligonucleotide Array Sequence Analysis

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Maria T Larsen; Corinna C Pedersen; Kim Theilgaard-Mönch; Niels Borregaard; Mattias Häger; Christoffer Hother; Jack B Cowland
MicroRNA Profiling in Human Neutrophils during Bone Marrow Granulopoiesis and In Vivo Exudation.
Frederik Otzen Bagger; Johan Jendholm; Bogumil Kaczkowski; Nicolas Rapin; Kim Theilgaard-Mönch; Lina A Thoren; Ole Winther; Bo T Porse
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.
Frederik Otzen Bagger; Johan Jendholm; Bogumil Kaczkowski; Nicolas Rapin; Kim Theilgaard-Mönch; Ole Winther; Bo Porse
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis.

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2013: Maria T Larsen; Corinna C Pedersen; Kim Theilgaard-Mönch; Niels Borregaard; Mattias Häger; Christoffer Hother; Jack B Cowland
MicroRNA Profiling in Human Neutrophils during Bone Marrow Granulopoiesis and In Vivo Exudation.
PloS one 2013;8(3):e58454.
2013: Frederik Otzen Bagger; Johan Jendholm; Bogumil Kaczkowski; Nicolas Rapin; Kim Theilgaard-Mönch; Lina A Thoren; Ole Winther; Bo T Porse
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.
Nucleic acids research 2013;41(Database issue):D1034-9.
2012: Frederik Otzen Bagger; Johan Jendholm; Bogumil Kaczkowski; Nicolas Rapin; Kim Theilgaard-Mönch; Ole Winther; Bo Porse
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis.
Blood 2012;119(26):6394-5.
2012: Marie S Hasemann; Claus Nerlov; Thomas Å Pedersen; Mikkel Bruhn Schuster; Kim Theilgaard-Mönch; Anne-Katrine Frank; Bo T Porse
Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency.
PloS one 2012;7(6):e38841.
2011: Helena Mora-Jensen; Bo Porse; Niels Borregaad; Anna Fossum; Johan Jendholm; Niels Borregaard; Kim Theilgaard-Mönch
Technical advance: immunophenotypical characterization of human neutrophil differentiation.
Journal of leukocyte biology 2011;90(3):629-34.
2010: T T Marstrand; Rehannah Borup; A Willer; Niels Borregaard; Albin Sandelin; Bo T Porse; Kim Theilgaard-Mönch
A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia.
Leukemia 2010;24(7):1265-75.
2008: Joachim Weischenfeldt; Inge Damgaard; David Bryder; Kim Theilgaard-Mönch; Lina A Thoren; Omid Niazi; Sten Eirik W Jacobsen; Claus Nerlov; Bo T Porse
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Genes & development 2008;22(10):1381-96.
2008: Lars C Jacobsen; Ole E Sørensen; Jack B Cowland; Niels Borregaard; Kim Theilgaard-Mönch
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Journal of leukocyte biology 2008;83(5):1155-64.
2008: Marie S Hasemann; Inge Damgaard; Mikkel Bruhn Schuster; Kim Theilgaard-Mönch; Annette B Sørensen; Alan Mrsic; Thijs Krugers; Bauke Ylstra; Finn Skou Pedersen; Claus Nerlov; Bo T Porse
Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.
Blood 2008;111(8):4309-21.
2008: Peggy Kirstetter; Mikkel B Schuster; Oksana Bereshchenko; Susan Moore; Heidi Dvinge; Elke Kurz; Kim Theilgaard-Mönch; Robert Månsson; Thomas A Pedersen; Thomas Pabst; Evelin Schrock; Bo T Porse; Sten Eirik W Jacobsen; Paul Bertone; Daniel G Tenen; Claus Nerlov
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Cancer cell 2008;13(4):299-310.
2007: Lars Nilsson; Patrik Edén; Eleonor Olsson; Robert Månsson; Ingbritt Astrand-Grundström; Bodil Strömbeck; Kim Theilgaard-Mönch; Kristina Anderson; Robert Hast; Eva Hellström-Lindberg; Jan Samuelsson; Gösta Bergh; Claus Nerlov; Bertil Johansson; Mikael Sigvardsson; Ake Borg; Sten Eirik W Jacobsen
The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.
Blood 2007;110(8):3005-14.
2007: Niels Borregaard; Ole E Sørensen; Kim Theilgaard-Mönch
Neutrophil granules: a library of innate immunity proteins.
Trends in immunology 2007;28(8):340-5.
2007: Lars C Jacobsen; Kim Theilgaard-Mönch; Erik I Christensen; Niels Borregaard
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Blood 2007;109(7):3084-7.
2007: Adrian P Bracken; Daniela Kleine-Kohlbrecher; Nikolaj Dietrich; Diego Pasini; GAETANO GARGIULO; Chantal Beekman; Kim Theilgaard-Mönch; Saverio Minucci; Bo T Porse; Jean-Christophe Marine; Klaus H Hansen; Kristian Helin
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Genes & development 2007;21(5):525-30.
2006: Kim Theilgaard-Mönch; Lars C Jacobsen; Marianne Jensby Nielsen; Thomas Rasmussen; Lene Udby; Maged Gharib; Peter Arkwright; Adrian F Gombart; Jero Calafat; Søren K Moestrup; Bo T Porse; Niels Borregaard
Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.
Blood 2006;108(1):353-61.
2006: Robert F Wynn; M Sood; Kim Theilgaard-Mönch; C J Jones; Adrian F Gombart; Maged Gharib; H P Koeffler; Niels Borregaard; Peter Arkwright
Intractable diarrhoea of infancy caused by neutrophil specific granule deficiency and cured by stem cell transplantation.
Gut 2006;55(2):292-3.
2006: Kim Theilgaard-Mönch; Bo T Porse; Niels Borregaard
Systems biology of neutrophil differentiation and immune response.
Current opinion in immunology 2006;18(1):54-60.
2005: Heidi Rye Hudlebusch; Kim Theilgaard-Mönch; Marianne Lodahl; Hans E Johnsen; Thomas Rasmussen
Identification of ID-1 as a potential target gene of MMSET in multiple myeloma.
British journal of haematology 2005;130(5):700-8.
2005: Kim Theilgaard-Mönch; Lars C Jacobsen; Thomas Rasmussen; Carsten U Niemann; Lene Udby; Rehannah Borup; Maged Gharib; Peter Arkwright; Adrian F Gombart; Jero Calafat; Bo T Porse; Niels Borregaard
Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.
Journal of leukocyte biology 2005;78(2):462-70.
2005: Bo T Porse; David Bryder; Kim Theilgaard-Mönch; Marie S Hasemann; Kristina Anderson; Inge Damgaard; Sten Eirik W Jacobsen; Claus Nerlov
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.
The Journal of experimental medicine 2005;202(1):85-96.
2005: Niels Borregaard; Kim Theilgaard-Mönch; Jack B Cowland; Mona Ståhle; Ole E Sørensen
Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place.
Journal of leukocyte biology 2005;77(4):439-43.
2005: Kim Theilgaard-Mönch; Lars C Jacobsen; Rehannah Borup; Thomas Rasmussen; Malene Digmann Bjerregaard; Omid Niazi; Jack B Cowland; Niels Borregaard
The transcriptional program of terminal granulocytic differentiation.
Blood 2005;105(4):1785-96.
2004: Kim Theilgaard-Mönch; Steen Knudsen; Per Follin; Niels Borregaard
The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7684-93.
2003: Kim Theilgaard-Mönch; K Raaschou-Jensen; K Schjødt; Carsten Heilmann; Lars L Vindeløv; Niels Jacobsen; Ebbe Dickmeiss
Pluripotent and myeloid-committed CD34+ subsets in hematopoietic stem cell allografts.
Bone marrow transplantation 2003;32(12):1125-33.
2003: Thomas Rasmussen; Kim Theilgaard-Mönch; Heidi Rye Hudlebusch; Marianne Lodahl; Hans E Johnsen; Inger Marie S Dahl
Occurrence of dysregulated oncogenes in primary plasma cells representing consecutive stages of myeloma pathogenesis: indications for different disease entities.
British journal of haematology 2003;123(2):253-62.
2003: Ole E Sørensen; Jack B Cowland; Kim Theilgaard-Mönch; Lide Liu; Tomas Ganz; Niels Borregaard
Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5583-9.
2002: Ewa Sitnicka; David Bryder; Kim Theilgaard-Mönch; Natalija Buza-Vidas; Jörgen Adolfsson; Sten Eirik W Jacobsen
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.
Immunity 2002;17(4):463-72.
2001: Kim Theilgaard-Mönch; K Raaschou-Jensen; H Palm; K Schjødt; Carsten Heilmann; Lars L Vindeløv; Niels Jacobsen; Ebbe Dickmeiss
Flow cytometric assessment of lymphocyte subsets, lymphoid progenitors, and hematopoietic stem cells in allogeneic stem cell grafts.
Bone marrow transplantation 2001;28(11):1073-82.
2001: Jörgen Adolfsson; Ole-Johan Borge; David Bryder; Kim Theilgaard-Mönch; Ingbritt Astrand-Grundström; Ewa Sitnicka; Yutaka Sasaki; Sten Eirik W Jacobsen
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity.
Immunity 2001;15(4):659-69.
2001: David Bryder; Veslemøy Ramsfjell; Ingunn Dybedal; Kim Theilgaard-Mönch; C M Högerkorp; Jörgen Adolfsson; Ole-Johan Borge; Sten Eirik W Jacobsen
Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.
The Journal of experimental medicine 2001;194(7):941-52.
2001: Kim Theilgaard-Mönch; Jack B Cowland; Niels Borregaard
Profiling of gene expression in individual hematopoietic cells by global mRNA amplification and slot blot analysis.
Journal of immunological methods 2001;252(1-2):175-89.
2001: Niels Borregaard; Kim Theilgaard-Mönch; Ole E Sørensen; Jack B Cowland
Regulation of human neutrophil granule protein expression.
Current opinion in hematology 2001;8(1):23-7.
1999: Kim Theilgaard-Mönch; K Raaschou-Jensen; Carsten Heilmann; Heidi Andersen; J Bock; C A Russel; Lars L Vindeløv; Niels Jacobsen; Ebbe Dickmeiss
A comparative study of CD34+ cells, CD34+ subsets, colony forming cells and cobblestone area forming cells in cord blood and bone marrow allografts.
European journal of haematology 1999;62(3):174-83.
1999: Kim Theilgaard-Mönch; K Raaschou-Jensen; Heidi Andersen; Charlotte Astrid Russell; Lars L Vindeløv; Niels Jacobsen; Ebbe Dickmeiss
Single leukapheresis products collected from healthy donors after the administration of granulocyte colony-stimulating factor contain ten-fold higher numbers of long-term reconstituting hematopoietic progenitor cells than conventional bone marrow allografts.
Bone marrow transplantation 1999;23(3):243-9.