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Gustavo Brum

Research Profile

Chemicals & Drugs

Living Beings

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Physiology

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Muscle Contraction

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Publications

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Lourdes Figueroa; Carlo Manno; Atsuya Momotake; Lothar A Blatter; Gustavo Brum; Graham C R Ellis-Davies; Vyacheslav M Shkryl; Jingsong Zhou; Eduardo Ríos
Synthetic localized calcium transients directly probe signalling mechanisms in skeletal muscle.
Monika Sztretye; Jianxun Yi; Jingsong Zhou; Leandro Royer; Paul Allen; Gustavo Brum; Lourdes Figueroa; Eduardo Ríos
Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca(2+) release in skeletal muscle.
Eduardo Ríos; Jingsong Zhou; Gustavo Brum; Bradley S Launikonis; Michael D Stern
Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians.

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All Publications

2012: Lourdes Figueroa; Carlo Manno; Atsuya Momotake; Lothar A Blatter; Gustavo Brum; Graham C R Ellis-Davies; Vyacheslav M Shkryl; Jingsong Zhou; Eduardo Ríos
Synthetic localized calcium transients directly probe signalling mechanisms in skeletal muscle.
The Journal of physiology 2012;590(Pt 6):1389-411.
2011: Monika Sztretye; Jianxun Yi; Jingsong Zhou; Leandro Royer; Paul Allen; Gustavo Brum; Lourdes Figueroa; Eduardo Ríos
Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca(2+) release in skeletal muscle.
The Journal of general physiology 2011;138(2):231-47.
2008: Eduardo Ríos; Jingsong Zhou; Gustavo Brum; Bradley S Launikonis; Michael D Stern
Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians.
The Journal of general physiology 2008;131(4):335-48.
2007: Sandrine Pouvreau; Leandro Royer; Jianxun Yi; Gustavo Brum; Gerhard Meissner; Eduardo Ríos; Jingsong Zhou
Ca(2+) sparks operated by membrane depolarization require isoform 3 ryanodine receptor channels in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5235-40.
2006: Bradley S Launikonis; Jingsong Zhou; Demetrio Santiago; Gustavo Brum; Eduardo Ríos
The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle.
The Journal of general physiology 2006;128(1):45-54.
2006: Bradley S Launikonis; Jingsong Zhou; Leandro Royer; Thomas R Shannon; Gustavo Brum; Eduardo Ríos
Depletion "skraps" and dynamic buffering inside the cellular calcium store.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2982-7.
2006: Eduardo Ríos; Bradley S Launikonis; Leandro Royer; Gustavo Brum; Jingsong Zhou
The elusive role of store depletion in the control of intracellular calcium release.
Journal of muscle research and cell motility 2006;27(5-7):337-50.
2006: Nazira Píriz; Gustavo Brum; Gonzalo Pizarro
Differential sensitivity to perchlorate and caffeine of tetracaine-resistant Ca2+ release in frog skeletal muscle.
Journal of muscle research and cell motility 2006;27(3-4):221-34.
2005: Jinsong Zhou; Gustavo Brum; Adom González; Bradley S Launikonis; Michael D Stern; Eduardo Ríos
Concerted vs. sequential. Two activation patterns of vast arrays of intracellular Ca2+ channels in muscle.
The Journal of general physiology 2005;126(4):301-9.
2005: Bradley S Launikonis; Jingsong Zhou; Leandro Royer; Thomas R Shannon; Gustavo Brum; Eduardo Ríos
Confocal imaging of [Ca2+] in cellular organelles by SEER, shifted excitation and emission ratioing of fluorescence.
The Journal of physiology 2005;567(Pt 2):523-43.
2004: Jingsong Zhou; Bradley S Launikonis; Eduardo Ríos; Gustavo Brum
Regulation of Ca2+ sparks by Ca2+ and Mg2+ in mammalian and amphibian muscle. An RyR isoform-specific role in excitation-contraction coupling?
The Journal of general physiology 2004;124(4):409-28.
2004: Laszlo Csernoch; J Zhou; Michael D Stern; Gustavo Brum; Eduardo Ríos
The elementary events of Ca2+ release elicited by membrane depolarization in mammalian muscle.
The Journal of physiology 2004;557(Pt 1):43-58.
2003: Jingsong Zhou; Gustavo Brum; A Gonzalez; Bradley S Launikonis; Michael D Stern; E Rios
Ca2+ sparks and embers of mammalian muscle. Properties of the sources.
The Journal of general physiology 2003;122(1):95-114.
2003: Gustavo Brum; Nazira Piriz; Rafael DeArmas; Eduardo Rios; Michael Stern; Gonzalo Pizarro
Differential effects of voltage-dependent inactivation and local anesthetics on kinetic phases of Ca2+ release in frog skeletal muscle.
Biophysical journal 2003;85(1):245-54.
2003: P Artigas; Gonzalo Ferreira; N Reyes; Gustavo Brum; Gonzalo Pizarro
Effects of the enantiomers of BayK 8644 on the charge movement of L-type Ca channels in guinea-pig ventricular myocytes.
The Journal of membrane biology 2003;193(3):215-27.
2002: Eduardo Ríos; Gustavo Brum
Ca2+ release flux underlying Ca2+ transients and Ca2+ sparks in skeletal muscle.
Frontiers in bioscience : a journal and virtual library 2002;7():d1195-211.
2000: Gustavo Brum; Adom González; J Rengifo; Natalia Shirokova; Eduardo Ríos
Fast imaging in two dimensions resolves extensive sources of Ca2+ sparks in frog skeletal muscle.
The Journal of physiology 2000;528(Pt 3):419-33.
2000: Adom González; WG Kirsch; Natalia Shirokova; Gonzalo Pizarro; Gustavo Brum; I N Pessah; Michael D Stern; Heping Cheng; Eduardo Ríos
Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4380-5.
1998: R De Armas; S González; Gustavo Brum; Gonzalo Pizarro
Effects of 2,3-butanedione monoxime on excitation-contraction coupling in frog twitch fibres.
Journal of muscle research and cell motility 1998;19(8):961-77.
1997: Gonzalo Ferreira; P Artigas; Gonzalo Pizarro; Gustavo Brum
Butanedione monoxime promotes voltage-dependent inactivation of L-type calcium channels in heart. Effects on gating currents.
Journal of molecular and cellular cardiology 1997;29(2):777-87.
1988: Gustavo Brum; R Fitts; Gonzalo Pizarro; Eduardo Ríos
Voltage sensors of the frog skeletal muscle membrane require calcium to function in excitation-contraction coupling.
The Journal of physiology 1988;398():475-505.
1988: Gustavo Brum; Eduardo Ríos; E Stéfani
Effects of extracellular calcium on calcium movements of excitation-contraction coupling in frog skeletal muscle fibres.
The Journal of physiology 1988;398():441-73.
1987: Gustavo Brum; E Rios
Intramembrane charge movement in frog skeletal muscle fibres. Properties of charge 2.
The Journal of physiology 1987;387():489-517.
1987: Gustavo Brum; E Stefani; E Rios
Simultaneous measurements of Ca2+ currents and intracellular Ca2+ concentrations in single skeletal muscle fibers of the frog.
Canadian journal of physiology and pharmacology 1987;65(4):681-5.
1987: E Rios; Gustavo Brum
Involvement of dihydropyridine receptors in excitation-contraction coupling in skeletal muscle.
Nature 1987;325(6106):717-20.