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albert heck

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TOP 3
Norton Kitagawa; Hortense Mazon; albert heck; Stephan Wilkens
Stoichiometry of the peripheral stalk subunits E and G of yeast V1-ATPase determined by mass spectrometry.
Vera Alverdi; Hortense Mazon; Cees Versluis; Wieger Hemrika; Gennaro Esposito; Robert H H van den Heuvel; Arjen Scholten; albert heck
cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.
Martijn W H Pinkse; shabaz mohammed; Joost W Gouw; Bas van Breukelen; Harmjan R Vos; albert heck
Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster.

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All Publications

2008: Norton Kitagawa; Hortense Mazon; albert heck; Stephan Wilkens
Stoichiometry of the peripheral stalk subunits E and G of yeast V1-ATPase determined by mass spectrometry.
The Journal of biological chemistry 2008;283(6):3329-37.
2008: Vera Alverdi; Hortense Mazon; Cees Versluis; Wieger Hemrika; Gennaro Esposito; Robert H H van den Heuvel; Arjen Scholten; albert heck
cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.
Journal of molecular biology 2008;375(5):1380-93.
2008: Martijn W H Pinkse; shabaz mohammed; Joost W Gouw; Bas van Breukelen; Harmjan R Vos; albert heck
Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster.
Journal of proteome research 2008;7(2):687-97.
2008: Jeroen Krijgsveld; Anthony D Whetton; Bonghee Lee; Ihor Lemischka; Steve Oh; Martin Pera; Christine Mummery; albert heck
Proteome biology of stem cells: a new joint HUPO and ISSCR initiative.
Molecular & cellular proteomics : MCP 2008;7(1):204-5.
2008: Silvia A Synowsky; albert heck
The yeast Ski complex is a hetero-tetramer.
Protein science : a publication of the Protein Society 2008;17(1):119-25.
2007: Wilma Dormeyer; shabaz mohammed; Bas van Breukelen; Jeroen Krijgsveld; albert heck
Targeted analysis of protein termini.
Journal of proteome research 2007;6(12):4634-45.
2007: Simone Lemeer; Rob Ruijtenbeek; Martijn W H Pinkse; Chris Jopling; albert heck; Jeroen den Hertog; Monique Slijper
Endogenous phosphotyrosine signaling in zebrafish embryos.
Molecular & cellular proteomics : MCP 2007;6(12):2088-99.
2007: Marco J L de Groot; Pascale Daran-Lapujade; Bas van Breukelen; Theo A Knijnenburg; Erik A F De Hulster; Marcel J T Reinders; Jack T. Pronk; albert heck; Monique Slijper
Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes.
Microbiology (Reading, England) 2007;153(Pt 11):3864-78.
2007: Pascale Daran-Lapujade; Sergio Rossell; Walter M van Gulik; Marijke A H Luttik; Marco J L de Groot; Monique Slijper; albert heck; Jean-Marc Daran; Johannes H De Winde; Hans V Westerhoff; Jack T. Pronk; Barbara M Bakker
The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15753-8.
2007: Kristina Lorenzen; Alessandro Vannini; Patrick Cramer; albert heck
Structural biology of RNA polymerase III: mass spectrometry elucidates subcomplex architecture.
Structure (London, England : 1993) 2007;15(10):1237-45.
2007: Jeroen Kool; Léon Reubsaet; Feikje Wesseldijk; Raquel T Maravilha; Martijn W Pinkse; Clive D'Santos; Jacobus J van Hilten; Freek Jan Zijlstra; albert heck
Suction blister fluid as potential body fluid for biomarker proteins.
Proteomics 2007;7(20):3638-50.
2007: Dennis Van Hoof; Martijn W H Pinkse; Dorien Ward-Van Oostwaard; Christine L Mummery; albert heck; Jeroen Krijgsveld
An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics.
Nature methods 2007;4(9):677-8.
2007: Christopher Taylor; Norman W Paton; Kathryn S Lilley; Pierre-Alain Binz; Randall K Julian; Andrew R Jones; Weimin Zhu; Rolf Apweiler; Ruedi Aebersold; Eric Deutsch; Michael J Dunn; albert heck; Alexander Leitner; Marcus Macht; Matthias Mann; Lennart Martens; Thomas A Neubert; Scott D Patterson; Peipei Ping; Sean L Seymour; Puneet Souda; Akira Tsugita; Joel Vandekerckhove; Thomas M Vondriska; Julian P Whitelegge; Marc R Wilkins; Ioannnis Xenarios; John R Yates; Henning Hermjakob
The minimum information about a proteomics experiment (MIAPE).
Nature biotechnology 2007;25(8):887-93.
2007: Joris J Benschop; shabaz mohammed; Martina O'Flaherty; albert heck; Monique Slijper; Frank L H Menke
Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.
Molecular & cellular proteomics : MCP 2007;6(7):1198-214.
2007: Esther van Duijn; albert heck; Saskia M van der Vies
Inter-ring communication allows the GroEL chaperonin complex to distinguish between different substrates.
Protein science : a publication of the Protein Society 2007;16(5):956-65.
2007: Erich Brunner; Christian H Ahrens; Sonali Mohanty; Hansruedi Baetschmann; Sandra Loevenich; Frank Potthast; Eric Deutsch; Christian Panse; Ulrik de Lichtenberg; Oliver Rinner; Hookeun Lee; Patrick G A Pedrioli; Johan Malmstrom; Katja Koehler; Sabine Schrimpf; Jeroen Krijgsveld; Floyd Kregenow; albert heck; Ernst Hafen; Ralph Schlapbach; Ruedi Aebersold
A high-quality catalog of the Drosophila melanogaster proteome.
Nature biotechnology 2007;25(5):576-83.
2007: Arjen Scholten; Toon A B van Veen; Marc A Vos; albert heck
Diversity of cAMP-dependent protein kinase isoforms and their anchoring proteins in mouse ventricular tissue.
Journal of proteome research 2007;6(5):1705-17.
2007: Will A Stanley; Kees Versluis; Carsten Schultz; albert heck; Matthias Wilmanns
Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay.
Archives of biochemistry and biophysics 2007;461(1):50-8.
2007: Arjen Scholten; Hendrik Fuss; albert heck; Wolfgang R Dostmann
The hinge region operates as a stability switch in cGMP-dependent protein kinase I alpha.
The FEBS journal 2007;274(9):2274-86.
2007: Hortense Mazon; Krisztina Gábor; David Leys; albert heck; John van der Oost; Robert H H van den Heuvel
Transcriptional activation by CprK1 is regulated by protein structural changes induced by effector binding and redox state.
The Journal of biological chemistry 2007;282(15):11281-90.
2007: Romulus Mihalca; Yuri E M van der Burgt; albert heck; Ron M A Heeren
Disulfide bond cleavages observed in SORI-CID of three nonapeptides complexed with divalent transition-metal cations.
Journal of mass spectrometry : JMS 2007;42(4):450-8.
2007: Monique B Kamphuis; Maria Chiara Monti; Robert H H van den Heuvel; Sandra Santos-Sierra; Gert E Folkers; Marc Lemonnier; Ramón Díaz-Orejas; albert heck; Rolf Boelens
Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE.
Proteins 2007;67(1):219-31.
2007: Paul J Boersema; Nullin Divecha; albert heck; shabaz mohammed
Evaluation and optimization of ZIC-HILIC-RP as an alternative MudPIT strategy.
Journal of proteome research 2007;6(3):937-46.
2007: Natasja F C Visser; Arjen Scholten; Robert H H van den Heuvel; albert heck
Surface-plasmon-resonance-based chemical proteomics: efficient specific extraction and semiquantitative identification of cyclic nucleotide-binding proteins from cellular lysates by using a combination of surface plasmon resonance, sequential elution and liquid chromatography-tandem mass spectrometry.
Chembiochem : a European journal of chemical biology 2007;8(3):298-305.
2007: Anton Poliakov; Esther van Duijn; Gabriel C Lander; Chi-yu Fu; John E Johnson; Peter E Prevelige; albert heck
Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assemblies.
Journal of structural biology 2007;157(2):371-83.
2007: Simone Lemeer; Chris Jopling; Faris Naji; Rob Ruijtenbeek; Monique Slijper; albert heck; Jeroen den Hertog
Protein-tyrosine kinase activity profiling in knock down zebrafish embryos.
PloS one 2007;2(7):e581.
2007: Maria Chiara Monti; Ana M Hernández-Arriaga; Monique B Kamphuis; Juan López-Villarejo; albert heck; Rolf Boelens; Ramón Díaz-Orejas; Robert H H van den Heuvel
Interactions of Kid-Kis toxin-antitoxin complexes with the parD operator-promoter region of plasmid R1 are piloted by the Kis antitoxin and tuned by the stoichiometry of Kid-Kis oligomers.
Nucleic acids research 2007;35(5):1737-49.
2006: Alex J Poot; Eelco Ruijter; Timo Nuijens; Eef H C Dirksen; albert heck; Monique Slijper; Dirk T S Rijkers; Rob M J Liskamp
Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides.
Proteomics 2006;6(24):6394-9.
2006: Robert H H van den Heuvel; Esther van Duijn; Hortense Mazon; Silvia A Synowsky; Kristina Lorenzen; Cees Versluis; Stan J J Brouns; Dave Langridge; John van der Oost; John Hoyes; albert heck
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry.
Analytical chemistry 2006;78(21):7473-83.
2006: Rimco B J Geels; Saskia M van der Vies; albert heck; Ron M A Heeren
Electron capture dissociation as structural probe for noncovalent gas-phase protein assemblies.
Analytical chemistry 2006;78(20):7191-6.
2006: Jonathan R Halstead; Jacco van Rheenen; Mireille H J Snel; Sarah Meeuws; shabaz mohammed; Clive D'Santos; albert heck; Kees Jalink; Nullin Divecha
A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.
Current biology : CB 2006;16(18):1850-6.
2006: David R Jones; Yvette Bultsma; Willem-Jan Keune; Jonathan R Halstead; Dallila Elouarrat; shabaz mohammed; albert heck; Clive D'Santos; Nullin Divecha
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.
Molecular cell 2006;23(5):685-95.
2006: Eef H C Dirksen; Martijn W H Pinkse; Dirk T S Rijkers; Jacqueline Cloos; Rob M J Liskamp; Monique Slijper; albert heck
Investigating the dynamic nature of the interactions between nuclear proteins and histones upon DNA damage using an immobilized peptide chemical proteomics approach.
Journal of proteome research 2006;5(9):2380-8.
2006: Silvia A Synowsky; Robert H H van den Heuvel; shabaz mohammed; Pim W W M Pijnappel; albert heck
Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.
Molecular & cellular proteomics : MCP 2006;5(9):1581-92.
2006: Luis F Garcia-Alles; Kees Versluis; laurent maveyraud; Ana Tesouro Vallina; Sebastiano Sansano; Nana Fatimath Bello; Hans-Jürgen Gober; Valérie Guillet; Henri de la Salle; Germain Puzo; Lucia Mori; albert heck; Gennaro De Libero; Lionel Mourey
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b.
The EMBO journal 2006;25(15):3684-92.
2006: Dennis Van Hoof; Christine L Mummery; albert heck; Jeroen Krijgsveld
Embryonic stem cell proteomics.
Expert review of proteomics 2006;3(4):427-37.
2006: Dorien Wijte; Ad L de Jong; Marijke A E Mol; Ben L M van Baar; albert heck
ProteomIQ blue, a potent post-stain for the visualization and subsequent mass spectrometry based identification of fluorescent stained proteins on 2D-gels.
Journal of proteome research 2006;5(8):2033-8.
2006: Jeroen Krijgsveld; Sharon Gauci; Wilma Dormeyer; albert heck
In-gel isoelectric focusing of peptides as a tool for improved protein identification.
Journal of proteome research 2006;5(7):1721-30.
2006: Arjen Scholten; Natasja F C Visser; Robert H H van den Heuvel; albert heck
Analysis of protein-protein interaction surfaces using a combination of efficient lysine acetylation and nanoLC-MALDI-MS/MS applied to the E9:Im9 bacteriotoxin--immunity protein complex.
Journal of the American Society for Mass Spectrometry 2006;17(7):983-94.
2006: Dennis Van Hoof; Passier Robert; Dorien Ward-van Oostwaard; Martijn W H Pinkse; albert heck; Christine L Mummery; Jeroen Krijgsveld
A quest for human and mouse embryonic stem cell-specific proteins.
Molecular & cellular proteomics : MCP 2006;5(7):1261-73.
2006: Arjen Scholten; Mee Kian Poh; Toon A B van Veen; Bas van Breukelen; Marc A Vos; albert heck
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and highly abundant AKAP.
Journal of proteome research 2006;5(6):1435-47.
2006: Hugo D Meiring; Ernst C Soethout; Martien C M Poelen; Dennis Mooibroek; Ronald Hoogerbrugge; hans timmermans; Claire J P Boog; albert heck; Ad P J M de Jong; Cécile A C M van Els
Stable isotope tagging of epitopes: a highly selective strategy for the identification of major histocompatibility complex class I-associated peptides induced upon viral infection.
Molecular & cellular proteomics : MCP 2006;5(5):902-13.
2006: Esther van Duijn; Douglas A Simmons; Robert H H van den Heuvel; Patrick J Bakkes; Harm van Heerikhuizen; Ron M A Heeren; Carol V Robinson; Saskia M van der Vies; albert heck
Tandem mass spectrometry of intact GroEL-substrate complexes reveals substrate-specific conformational changes in the trans ring.
Journal of the American Chemical Society 2006;128(14):4694-702.
2006: Michael R Eman; Elsa Regan-Klapisz; Martijn W H Pinkse; Inge M Koop; Johan Haverkamp; albert heck; Arie J Verkleij; Jan Andries Post
Protein expression dynamics during replicative senescence of endothelial cells studied by 2-D difference in-gel electrophoresis.
Electrophoresis 2006;27(8):1669-82.
2006: Ana P Yatsuda; Nicole Bakker; Jeroen Krijgsveld; David P Knox; albert heck; Erik de Vries
Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors.
Infection and immunity 2006;74(3):1989-93.
2006: Eef H C Dirksen; Jacqueline Cloos; Boudewijn J M Braakhuis; Ruud H Brakenhoff; albert heck; Monique Slijper
Human lymphoblastoid proteome analysis reveals a role for the inhibitor of acetyltransferases complex in DNA double-strand break response.
Cancer research 2006;66(3):1473-80.
2006: Henry A Boumann; Jacob Gubbens; Martijn C Koorengevel; Chan-Seok Oh; Charles E Martin; albert heck; Jana Patton-Vogt; Susan A Henry; Ben de Kruijff; Anton I P M de Kroon
Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote.
Molecular biology of the cell 2006;17(2):1006-17.
2006: Bas van Breukelen; Arjan Barendregt; albert heck; Robert H H van den Heuvel
Resolving stoichiometries and oligomeric states of glutamate synthase protein complexes with curve fitting and simulation of electrospray mass spectra.
Rapid communications in mass spectrometry : RCM 2006;20(16):2490-6.
2006: Annemieke Kolkman; Pascale Daran-Lapujade; Asier Fullaondo; Maurien M A Olsthoorn; Jack T. Pronk; Monique Slijper; albert heck
Proteome analysis of yeast response to various nutrient limitations.
Molecular systems biology 2006;2():2006.0026.
2006: Romulus Mihalca; Yuri E M van der Burgt; Liam A McDonnell; Marc C Duursma; Iliya Cerjak; albert heck; Ron M A Heeren
Combined infrared multiphoton dissociation and electron-capture dissociation using co-linear and overlapping beams in Fourier transform ion cyclotron resonance mass spectrometry.
Rapid communications in mass spectrometry : RCM 2006;20(12):1838-44.
2005: Hans-Christian Siebert; Karin Born; Sabine André; Martin Frank; Herbert Kaltner; Claus-W von der Lieth; albert heck; Jesús Jiménez-Barbero; Jürgen Kopitz; Hans-Joachim Gabius
Carbohydrate chain of ganglioside GM1 as a ligand: identification of the binding strategies of three 15 mer peptides and their divergence from the binding modes of growth-regulatory galectin-1 and cholera toxin.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;12(2):388-402.
2005: Pieter van der Veken; Eef H C Dirksen; Eelco Ruijter; Ronald C Elgersma; albert heck; Dirk T S Rijkers; Monique Slijper; Rob M J Liskamp
Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides.
Chembiochem : a European journal of chemical biology 2005;6(12):2271-80.
2005: Nico J de Mol; M Isabel Catalina; Frank J Dekker; Marcel J E Fischer; albert heck; Rob M J Liskamp
Protein flexibility and ligand rigidity: a thermodynamic and kinetic study of ITAM-based ligand binding to Syk tandem SH2.
Chembiochem : a European journal of chemical biology 2005;6(12):2261-70.
2005: Annemieke Kolkman; Monique Slijper; albert heck
Development and application of proteomics technologies in Saccharomyces cerevisiae.
Trends in biotechnology 2005;23(12):598-604.
2005: Kees Kruithof; Miguel A Casado; Gabriela Guillena; Maarten R Egmond; Anca van der Kerk-van Hoof; albert heck; Robertus J M Klein Gebbink; Gerard van Koten
Lipase active-site-directed anchoring of organometallics: metallopincer/protein hybrids.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(23):6869-77.
2005: Anne J Kleinnijenhuis; albert heck; Marc C Duursma; Ron M A Heeren
Does double electron capture lead to the formation of biradicals? An ECD-SORI-CID study on lacticin 481.
Journal of the American Society for Mass Spectrometry 2005;16(10):1595-601.
2005: Robert H H van den Heuvel; Nora Tahallah; Nanne M Kamerbeek; Marco W Fraaije; Willem J H van Berkel; Dick B Janssen; albert heck
Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase.
The Journal of biological chemistry 2005;280(37):32115-21.
2005: Edwin Romijn; Chantal Christis; Marnix Wieffer; Joost W Gouw; Asier Fullaondo; Peter van Der Sluijs; Ineke Braakman; albert heck
Expression clustering reveals detailed co-expression patterns of functionally related proteins during B cell differentiation: a proteomic study using a combination of one-dimensional gel electrophoresis, LC-MS/MS, and stable isotope labeling by amino acids in cell culture (SILAC).
Molecular & cellular proteomics : MCP 2005;4(9):1297-310.
2005: Patrick Rodriguez; Edgar Bonte; Jeroen Krijgsveld; Katarzyna E Kolodziej; Boris Guyot; albert heck; Paresh Vyas; Ernie de Boer; Frank Grosveld; John Strouboulis
GATA-1 forms distinct activating and repressive complexes in erythroid cells.
The EMBO journal 2005;24(13):2354-66.
2005: M Isabel Catalina; Marcel J E Fischer; Frank J Dekker; Rob M J Liskamp; albert heck
Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.
Journal of the American Society for Mass Spectrometry 2005;16(7):1039-51.
2005: Esther F A Brandon; Ronald D van Ooijen; Rolf W Sparidans; Luis López Lázaro; albert heck; Jos H Beijnen; Jan H M Schellens
Structure elucidation of aplidine metabolites formed in vitro by human liver microsomes using triple quadrupole mass spectrometry.
Journal of mass spectrometry : JMS 2005;40(6):821-31.
2005: Bas W M Van Balkom; Renske A van Gestel; Jos F H M Brouwers; Jeroen Krijgsveld; Aloysius Tielens; albert heck; Jaap J van Hellemond
Mass spectrometric analysis of the Schistosoma mansoni tegumental sub-proteome.
Journal of proteome research 2005;4(3):958-66.
2005: Esther van Duijn; Patrick J Bakkes; Ron M A Heeren; Robert H H van den Heuvel; Harm van Heerikhuizen; Saskia M van der Vies; albert heck
Monitoring macromolecular complexes involved in the chaperonin-assisted protein folding cycle by mass spectrometry.
Nature methods 2005;2(5):371-6.
2005: Arnoud Groen; Simone Lemeer; Thea van der Wijk; John Overvoorde; albert heck; Arne Ostman; David Barford; Monique Slijper; Jeroen den Hertog
Differential oxidation of protein-tyrosine phosphatases.
The Journal of biological chemistry 2005;280(11):10298-304.
2005: Sabine André; Herbert Kaltner; Martin Lensch; Roland Russwurm; Hans-Christian Siebert; Christine Fallsehr; Emadeddin Emadeddin Tajkhorshid; albert heck; Magnus von Knebel Doeberitz; Hans-Joachim Gabius; Jürgen Kopitz
Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells.
International journal of cancer. Journal international du cancer 2005;114(1):46-57.
2005: Ewald T J van den Bremer; Anthony H Keeble; Colin Kleanthous; albert heck
Metal induced selectivity in phosphate ion binding in E9 DNase.
Chemical communications (Cambridge, England) 2005;(9):1137-9.
2005: Jan A van der Knaap; B R Prashanth Kumar; Yuri Moshkin; Karin Langenberg; Jeroen Krijgsveld; albert heck; François Karch; C Peter Verrijzer
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.
Molecular cell 2005;17(5):695-707.
2005: Annemieke Kolkman; Eef H C Dirksen; Monique Slijper; albert heck
Double standards in quantitative proteomics: direct comparative assessment of difference in gel electrophoresis and metabolic stable isotope labeling.
Molecular & cellular proteomics : MCP 2005;4(3):255-66.
2005: Maaike Neeft; Marnix Wieffer; Arjan S de Jong; Gabriela Negroiu; Corina H G Metz; Alexander van Loon; Janice Griffith; Jeroen Krijgsveld; Nico M Wulffraat; Henriette Koch; albert heck; Nils Brose; Monique J Kleijmeer; Peter van Der Sluijs
Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells.
Molecular biology of the cell 2005;16(2):731-41.
2005: M Isabel Catalina; Robert H H van den Heuvel; Esther van Duijn; albert heck
Decharging of globular proteins and protein complexes in electrospray.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(3):960-8.
2005: Robert H H van den Heuvel; Sara Gato; Cees Versluis; Pascal Gerbaux; Colin Kleanthous; albert heck
Real-time monitoring of enzymatic DNA hydrolysis by electrospray ionization mass spectrometry.
Nucleic acids research 2005;33(10):e96.
2005: Onno Kranenburg; Y Y J Gent; Edwin Romijn; Emile E Voest; albert heck; Martijn F B G Gebbink
Amyloid-beta-stimulated plasminogen activation by tissue-type plasminogen activator results in processing of neuroendocrine factors.
Neuroscience 2005;131(4):877-86.
2005: Annemieke Kolkman; Maurien M A Olsthoorn; Carola E M Heeremans; albert heck; Monique Slijper
Comparative proteome analysis of Saccharomyces cerevisiae grown in chemostat cultures limited for glucose or ethanol.
Molecular & cellular proteomics : MCP 2005;4(1):1-11.
2004: Romulus Mihalca; Anne J Kleinnijenhuis; Liam A McDonnell; albert heck; Ron M A Heeren
Electron capture dissociation at low temperatures reveals selective dissociations.
Journal of the American Society for Mass Spectrometry 2004;15(12):1869-73.
2004: albert heck; Jeroen Krijgsveld
Mass spectrometry-based quantitative proteomics.
Expert review of proteomics 2004;1(3):317-26.
2004: Martijn W H Pinkse; albert heck; Klaus Rumpel; Frank Pullen
Probing noncovalent protein-ligand interactions of the cGMP-dependent protein kinase using electrospray ionization time of flight mass spectrometry.
Journal of the American Society for Mass Spectrometry 2004;15(10):1392-9.
2004: Robert H H van den Heuvel; albert heck
Native protein mass spectrometry: from intact oligomers to functional machineries.
Current opinion in chemical biology 2004;8(5):519-26.
2004: Henry A Boumann; Patrick T K Chin; albert heck; Ben de Kruijff; Anton I P M de Kroon
The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro.
The Journal of biological chemistry 2004;279(39):40314-9.
2004: albert heck; Robert H H van den Heuvel
Investigation of intact protein complexes by mass spectrometry.
Mass spectrometry reviews 2004;23(5):368-89.
2004: Diana Avram; Edwin Romijn; Everard Pap; albert heck; Karel W A Wirtz
Identification of proteins in activated human neutrophils susceptible to tyrosyl radical attack. A proteomic study using a tyrosylating fluorophore.
Proteomics 2004;4(8):2397-407.
2004: Martijn W H Pinkse; Pauliina M Uitto; Martijn J Hilhorst; Bert Ooms; albert heck
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns.
Analytical chemistry 2004;76(14):3935-43.
2004: Henry A Boumann; Ben de Kruijff; albert heck; Anton I P M de Kroon
The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Ept1p and Cpt1p in yeast.
FEBS letters 2004;569(1-3):173-7.
2004: Nico J de Mol; M Isabel Catalina; Marcel J E Fischer; Isabelle Broutin; Claudia S Maier; albert heck
Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain.
Biochimica et biophysica acta 2004;1700(1):53-64.
2004: Berend Jan Bosch; Byron Martina; Ruurd van der Zee; Jean Lepault; Bert Jan Haijema; Cees Versluis; albert heck; Raoul De Groot; Albert D M E Osterhaus; Peter J M Rottier
Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8455-60.
2004: Ewald T J van den Bremer; Anthony H Keeble; Wim Jiskoot; Robin E J Spelbrink; Claudia S Maier; Arie van Hoek; Antonie J W G Visser; Richard James; Geoffrey R Moore; Colin Kleanthous; albert heck
Distinct conformational stability and functional activity of four highly homologous endonuclease colicins.
Protein science : a publication of the Protein Society 2004;13(5):1391-401.
2004: Anja N J A Ridder; Robin E J Spelbrink; Jeroen A A Demmers; Dirk T S Rijkers; Rob M J Liskamp; Josef Brunner; albert heck; Ben de Kruijff; J Antoinette Killian
Photo-crosslinking analysis of preferential interactions between a transmembrane peptide and matching lipids.
Biochemistry 2004;43(15):4482-9.
2004: Ewald T J van den Bremer; Anthony H Keeble; Antonie J W G Visser; Arie van Hoek; Colin Kleanthous; albert heck; Wim Jiskoot
Ligand-induced changes in the conformational dynamics of a bacterial cytotoxic endonuclease.
Biochemistry 2004;43(14):4347-55.
2004: Lisette Mohrmann; Karin Langenberg; Jeroen Krijgsveld; Arnoud J Kal; albert heck; C Peter Verrijzer
Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes.
Molecular and cellular biology 2004;24(8):3077-88.
2004: Robert H H van den Heuvel; Adrie Westphal; albert heck; Martin A Walsh; Stefano Rovida; Willem J H van Berkel; Andrea Mattevi
Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformation and support novel mechanism of action.
The Journal of biological chemistry 2004;279(13):12860-7.
2004: Matthijs Kol; Diederik W D Kuster; Henry A Boumann; Hans de Cock; albert heck; Ben de Kruijff; Anton I P M de Kroon
Uptake and remodeling of exogenous phosphatidylethanolamine in E. coli.
Biochimica et biophysica acta 2004;1636(2-3):205-12.
2004: Ellen Stokvis; Hilde Rosing; Mirjam Crul; M J Rieser; albert heck; J H M Schellens; Jos H Beijnen
Quantitative analysis of the novel anticancer drug ABT-518, a matrix metalloproteinase inhibitor, plus the screening of six metabolites in human plasma using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.
Journal of mass spectrometry : JMS 2004;39(3):277-88.
2004: Jan-Hendrik Beumer; Hilde Rosing; Michel J X Hillebrand; Lianda G A H Nan-Offeringa; Karen Foley; S Murray Yule; albert heck; Jan H M Schellens; Jos H Beijnen
Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2004;18(23):2839-48.
2003: René Houtman; Jeroen Krijgsveld; Mirjam Kool; Edwin Romijn; Frank A Redegeld; Frans P Nijkamp; albert heck; Ian Humphery-Smith
Lung proteome alterations in a mouse model for nonallergic asthma.
Proteomics 2003;3(10):2008-18.
2003: Jürgen Kopitz; Sabine André; Carolina von Reitzenstein; Kees Versluis; Herbert Kaltner; Roland J Pieters; Kojiro Wasano; Ichiro Kuwabara; Fu-Tong Liu; Michael Cantz; albert heck; Hans-Joachim Gabius
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells.
Oncogene 2003;22(40):6277-88.
2003: Jeroen Krijgsveld; René F Ketting; Tokameh Mahmoudi; Janik Johansen; Marta Artal-Sanz; C Peter Verrijzer; Ronald H Plasterk; albert heck
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.
Nature biotechnology 2003;21(8):927-31.
2003: Anne J Kleinnijenhuis; Marc C Duursma; Eefjan Breukink; Ron M A Heeren; albert heck
Localization of intramolecular monosulfide bridges in lantibiotics determined with electron capture induced dissociation.
Analytical chemistry 2003;75(13):3219-25.
2003: Edwin Romijn; Jeroen Krijgsveld; albert heck
Recent liquid chromatographic-(tandem) mass spectrometric applications in proteomics.
Journal of chromatography. A 2003;1000(1-2):589-608.
2003: Eefjan Breukink; Hester E van Heusden; Pauline J Vollmerhaus; Ewa Swiezewska; Livia Brunner; Suzanne Walker; albert heck; Ben de Kruijff
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes.
The Journal of biological chemistry 2003;278(22):19898-903.
2003: Ana P Yatsuda; Jeroen Krijgsveld; A W C A Cornelissen; albert heck; Erik de Vries
Comprehensive analysis of the secreted proteins of the parasite Haemonchus contortus reveals extensive sequence variation and differential immune recognition.
The Journal of biological chemistry 2003;278(19):16941-51.
2003: Jeroen A A Demmers; Annemieke van Dalen; Ben de Kruijff; albert heck; J Antoinette Killian
Interaction of the K+ channel KcsA with membrane phospholipids as studied by ESI mass spectrometry.
FEBS letters 2003;541(1-3):28-32.
2003: Pauline J Vollmerhaus; Eefjan Breukink; albert heck
Getting closer to the real bacterial cell wall target: biomolecular interactions of water-soluble lipid II with glycopeptide antibiotics.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(7):1556-65.
2003: Henry A Boumann; Mirjam J A Damen; Cees Versluis; albert heck; Ben de Kruijff; Anton I P M de Kroon
The two biosynthetic routes leading to phosphatidylcholine in yeast produce different sets of molecular species. Evidence for lipid remodeling.
Biochemistry 2003;42(10):3054-9.
2003: Martijn W H Pinkse; Claudia S Maier; Jung-In Kim; Byung-Ha Oh; albert heck
Macromolecular assembly of Helicobacter pylori urease investigated by mass spectrometry.
Journal of mass spectrometry : JMS 2003;38(3):315-20.
2003: Eelco van Anken; Edwin Romijn; Claudia Maggioni; Alexandre Mezghrani; Roberto Sitia; Ineke Braakman; albert heck
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion.
Immunity 2003;18(2):243-53.
2002: Nora Tahallah; Robert H H van den Heuvel; Willy A M Van Den Berg; Claudia S Maier; Willem J H van Berkel; albert heck
Cofactor-dependent assembly of the flavoenzyme vanillyl-alcohol oxidase.
The Journal of biological chemistry 2002;277(39):36425-32.
2002: Jeroen A A Demmers; Dirk T S Rijkers; Johan Haverkamp; J Antoinette Killian; albert heck
Factors affecting gas-phase deuterium scrambling in peptide ions and their implications for protein structure determination.
Journal of the American Chemical Society 2002;124(37):11191-8.
2002: Y Surroca; Johan Haverkamp; albert heck
Towards the understanding of molecular mechanisms in the early stages of heat-induced aggregation of beta-lactoglobulin AB.
Journal of chromatography. A 2002;970(1-2):275-85.
2002: Ivanka Jerić; Cornelis Versluis; Stefica Horvat; albert heck
Tracing glycoprotein structures: electrospray ionization tandem mass spectrometric analysis of sugar-peptide adducts.
Journal of mass spectrometry : JMS 2002;37(8):803-11.
2002: Hans-Christian Siebert; Shan-Yun Lü; Martin Frank; Jasper Kramer; Rainer Wechselberger; John Joosten; Sabine André; Kate Rittenhouse-Olson; René Roy; Claus-W von der Lieth; Robert Kaptein; Johannes Vliegenthart; albert heck; Hans-Joachim Gabius
Analysis of protein-carbohydrate interaction at the lower size limit of the protein part (15-mer peptide) by NMR spectroscopy, electrospray ionization mass spectrometry, and molecular modeling.
Biochemistry 2002;41(30):9707-17.
2002: Roberto T Bossi; Alessandro Aliverti; Debora Raimondi; Federico Fischer; Giuliana Zanetti; Davide Ferrari; Nora Tahallah; Claudia S Maier; albert heck; Menico Rizzi; Andrea Mattevi
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry 2002;41(28):8807-18.
2002: Ewald T J van den Bremer; Wim Jiskoot; Richard James; Geoffrey R Moore; Colin Kleanthous; albert heck; Claudia S Maier
Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry.
Protein science : a publication of the Protein Society 2002;11(7):1738-52.
2002: Arjan de Brouwer; C Versluis; Jan Westerman; B Roelofsen; albert heck; Karel W A Wirtz
Determination of the stability of the noncovalent phospholipid transfer protein-lipid complex by electrospray time-of-flight mass spectrometry.
Biochemistry 2002;41(25):8013-8.
2002: Francesca Corbellini; Roberto Fiammengo; Peter Timmerman; Mercedes Crego-Calama; Kees Versluis; albert heck; Ingrid Luyten; David N Reinhoudt
Guest encapsulation and self-assembly of molecular capsules in polar solvents via multiple ionic interactions.
Journal of the American Chemical Society 2002;124(23):6569-75.
2002: Pauline J Vollmerhaus; F W Alexander Tempels; J Jantina Kettenes-van den Bosch; albert heck
Molecular interactions of glycopeptide antibiotics investigated by affinity capillary electrophoresis and bioaffinity electrospray ionization-mass spectrometry.
Electrophoresis 2002;23(6):868-79.
2002: Rob Ruijtenbeek; Cees Versluis; albert heck; Frank A Redegeld; Frans P Nijkamp; Rob M J Liskamp
Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.
Journal of mass spectrometry : JMS 2002;37(1):47-55.
2001: Jenny A Cadée; Mies J van Steenbergen; Cees Versluis; albert heck; Willy J M Underberg; Willem Den Otter; Wim Jiskoot; Wim E Hennink
Oxidation of recombinant human interleukin-2 by potassium peroxodisulfate.
Pharmaceutical research 2001;18(10):1461-7.
2001: Jeroen A A Demmers; Esther van Duijn; Johan Haverkamp; Denise V Greathouse; Roger E Koeppe; albert heck; J Antoinette Killian
Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry.
The Journal of biological chemistry 2001;276(37):34501-8.
2001: Joop C M Waterval; G Hommels; P Bestebreurtje; Cees Versluis; albert heck; Auke Bult; Henk Lingeman; Willy J M Underberg
Capillary electrophoretic bioanalysis of therapeutically active peptides with UV and mass spectrometric detection after on-capillary preconcentration.
Electrophoresis 2001;22(13):2709-16.
2001: Joop C M Waterval; P Bestebreurtje; Henk Lingeman; Cees Versluis; albert heck; Auke Bult; Willy J M Underberg
Robust and cost-effective capillary electrophoresis-mass spectrometry interfaces suitable for combination with on-line analyte preconcentration.
Electrophoresis 2001;22(13):2701-8.
2001: Cees Versluis; A van der Staaij; Ellen Stokvis; albert heck; B de Craene
Metastable ion formation and disparate charge separation in the gas-phase dissection of protein assemblies studied by orthogonal time-of-flight mass spectrometry.
Journal of the American Society for Mass Spectrometry 2001;12(3):329-36.
2001: P J Bonnici; M Damen; Joop C M Waterval; albert heck
Formation and efficacy of vancomycin group glycopeptide antibiotic stereoisomers studied by capillary electrophoresis and bioaffinity mass spectrometry.
Analytical biochemistry 2001;290(2):292-301.
2001: M Roscić; C Versluis; A J Kleinnijenhuis; Stefica Horvat; albert heck
The early glycation products of the Maillard reaction: mass spectrometric characterization of novel imidazolidinones derived from an opioid pentapeptide and glucose.
Rapid communications in mass spectrometry : RCM 2001;15(12):1022-9.
2001: Nora Tahallah; Martijn W H Pinkse; Claudia S Maier; albert heck
The effect of the source pressure on the abundance of ions of noncovalent protein assemblies in an electrospray ionization orthogonal time-of-flight instrument.
Rapid communications in mass spectrometry : RCM 2001;15(8):596-601.
2001: albert heck; P J Bonnici; Eefjan Breukink; D Morris; M Wills
Modification and inhibition of vancomycin group antibiotics by formaldehyde and acetaldehyde.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(4):910-6.
2000: Ellen Stokvis; Susan L Clugston; John F Honek; albert heck
Characterization of glyoxalase I (E. coli)-inhibitor interactions by electrospray time-of-flight mass spectrometry and enzyme kinetic analysis.
Journal of protein chemistry 2000;19(5):389-97.
2000: MJ van Maanen; K Doesburg Smits; JM Damen; albert heck; Jos H Beijnen
Stability of thioTEPA and its metabolites, TEPA, monochloroTEPA and thioTEPA-mercapturate, in plasma and urine.
International journal of pharmaceutics 2000;200(2):187-94.
2000: Bastiaan Nuijen; Marjan Bouma; RE Henrar; Pablo Floriano; José Jimeno; Herre Talsma; J Jantina Kettenes-van den Bosch; albert heck; Auke Bult; Jos H Beijnen
Pharmaceutical development of a parenteral lyophilized formulation of the novel antitumor agent aplidine.
PDA journal of pharmaceutical science and technology / PDA 2000;54(3):193-208.
2000: Jeroen A A Demmers; Johan Haverkamp; albert heck; Roger E Koeppe; J Antoinette Killian
Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3189-94.
2000: Willem J H van Berkel; Robert H H van den Heuvel; Cees Versluis; albert heck
Detection of intact megaDalton protein assemblies of vanillyl-alcohol oxidase by mass spectrometry.
Protein science : a publication of the Protein Society 2000;9(3):435-9.
2000: T Staroske; D P O'Brien; T J Jørgensen; P Roepstorff; D H Williams; albert heck
The formation of heterodimers by vancomycin group antibiotics.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(3):504-9.
1999: A van de Kerk-van Hoof; albert heck
Interactions of alpha- and beta-avoparcin with bacterial cell-wall receptor-mimicking peptides studied by electrospray ionization mass spectrometry.
The Journal of antimicrobial chemotherapy 1999;44(5):593-9.
1999: MJ van Maanen; I M Tijhof; JM Damen; Cees Versluis; J J van den Bosch; albert heck; Sjoerd Rodenhuis; Jos H Beijnen
A search for new metabolites of N,N',N''-triethylenethiophosphoramide.
Cancer research 1999;59(18):4720-4.
1999: Anca van der Kerk-van Hoof; albert heck
Covalent and non-covalent dissociations of gas-phase complexes of avoparcin and bacterial receptor mimicking precursor peptides studied by collisionally activated decomposition mass spectrometry.
Journal of mass spectrometry : JMS 1999;34(8):813-9.
1999: Daniel Lafitte; albert heck; TJ Hill; K Jumel; S E Harding; Peter J Derrick
Evidence of noncovalent dimerization of calmodulin.
European journal of biochemistry / FEBS 1999;261(1):337-44.
1998: H Lavanant; Peter J Derrick; albert heck; F A Mellon
Analysis of nisin A and some of its variants using Fourier transform ion cyclotron resonance mass spectrometry.
Analytical biochemistry 1998;255(1):74-89.