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David Largaespada

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Physiology

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Publications

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Collier Lara S; Adams David J; Hackett Christopher S; Bendzick Laura E; Akagi Keiko; Davies Michael N; Diers Miechaleen D; Rodriguez Fausto J; Bender Aaron M; Tieu Christina; Matise Ilze; Dupuy Adam J; Copeland Neal G; Jenkins Nancy A; Hodgson J Graeme; Weiss William A; Jenkins Robert B; Largaespada David A
Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.
Largaespada David A
Transposon-mediated mutagenesis of somatic cells in the mouse for cancer gene identification.
Johnson Kimberly J; Springer Nathan M; Bielinsky Anja-Katrin; Largaespada David A; Ross Julie A
Developmental origins of cancer.

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All Publications

2009: Collier Lara S; Adams David J; Hackett Christopher S; Bendzick Laura E; Akagi Keiko; Davies Michael N; Diers Miechaleen D; Rodriguez Fausto J; Bender Aaron M; Tieu Christina; Matise Ilze; Dupuy Adam J; Copeland Neal G; Jenkins Nancy A; Hodgson J Graeme; Weiss William A; Jenkins Robert B; Largaespada David A
Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.
Cancer research 2009;69(21):8429-37.
2009: Largaespada David A
Transposon-mediated mutagenesis of somatic cells in the mouse for cancer gene identification.
Methods (San Diego, Calif.) 2009;49(3):282-6.
2009: Johnson Kimberly J; Springer Nathan M; Bielinsky Anja-Katrin; Largaespada David A; Ross Julie A
Developmental origins of cancer.
Cancer research 2009;69(16):6375-7.
2009: Rahrmann Eric P; Collier Lara S; Knutson Todd P; Doyal Meghan E; Kuslak Sheri L; Green Laura E; Malinowski Rita L; Roethe Laura; Akagi Keiko; Waknitz Michelle; Huang Wei; Largaespada David A; Marker Paul C
Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen.
Cancer research 2009;69(10):4388-97.
2009: Starr Timothy K; Allaei Raha; Silverstein Kevin A T; Staggs Rodney A; Sarver Aaron L; Bergemann Tracy L; Gupta Mihir; O'Sullivan M Gerard; Matise Ilze; Dupuy Adam J; Collier Lara S; Powers Scott; Oberg Ann L; Asmann Yan W; Thibodeau Stephen N; Tessarollo Lino; Copeland Neal G; Jenkins Nancy A; Cormier Robert T; Largaespada David A
A transposon-based genetic screen in mice identifies genes altered in colorectal cancer.
Science (New York, N.Y.) 2009;323(5922):1747-50.
2009: Keng Vincent W; Villanueva Augusto; Chiang Derek Y; Dupuy Adam J; Ryan Barbara J; Matise Ilze; Silverstein Kevin A T; Sarver Aaron; Starr Timothy K; Akagi Keiko; Tessarollo Lino; Collier Lara S; Powers Scott; Lowe Scott W; Jenkins Nancy A; Copeland Neal G; Llovet Josep M; Largaespada David A
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.
Nature biotechnology 2009;27(3):264-74.
2009: Wiesner Stephen M; Decker Stacy A; Larson Jon D; Ericson Katya; Forster Colleen; Gallardo Jose L; Long Chunmei; Demorest Zachary L; Zamora Edward A; Low Walter C; SantaCruz Karen; Largaespada David A; Ohlfest John R
De novo induction of genetically engineered brain tumors in mice using plasmid DNA.
Cancer research 2009;69(2):431-9.
2009: Kim Won-Il; Matise Ilze; Diers Miechaleen D; Largaespada David A
RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.
Blood 2009;113(5):1086-96.
2009: Yin Bin; Delwel Ruud; Valk Peter J; Wallace Margaret R; Loh Mignon L; Shannon Kevin M; Largaespada David A
A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Blood 2009;113(5):1075-85.
2009: Largaespada David A
Transposon mutagenesis in mice.
Methods in molecular biology (Clifton, N.J.) 2009;530():379-90.
2008: Wangensteen Kirk J; Wilber Andrew; Keng Vincent W; He Zhiying; Matise Ilze; Wangensteen Laura; Carson Corey M; Chen Yixin; Steer Clifford J; McIvor R Scott; Largaespada David A; Wang Xin; Ekker Stephen C
A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver.
Hepatology (Baltimore, Md.) 2008;47(5):1714-24.
2008: Largaespada David A; Collier Lara S
Transposon-mediated mutagenesis in somatic cells: identification of transposon-genomic DNA junctions.
Methods in molecular biology (Clifton, N.J.) 2008;435():95-108.
2007: Kim Won-Il; Wiesner Stephen M; Largaespada David A
Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells.
Experimental hematology 2007;35(8):1231-9.
2007: Morgan Kelly J; Rowley Matthew A; Wiesner Stephen M; Hasz Diane E; Van Ness Brian; Largaespada David A
The GAP-related domain of neurofibromin attenuates proliferation and downregulates N- and K-Ras activation in Nf1-negative AML cells.
Leukemia research 2007;31(8):1107-13.
2007: Yin Bin; Largaespada David A
PCR-based procedures to isolate insertion sites of DNA elements.
BioTechniques 2007;43(1):79-84.
2007: Yin B; Tsai M L; Hasz D E; Rathe S K; Le Beau M M; Largaespada D A
A microarray study of altered gene expression after cytarabine resistance in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(5):1093-7.
2007: Kim Andrew; Morgan Kelly; Hasz Diane E; Wiesner Stephen M; Lauchle Jennifer O; Geurts Jennifer L; Diers Miechaleen D; Le Doan T; Kogan Scott C; Parada Luis F; Shannon Kevin; Largaespada David A
Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.
Blood 2007;109(4):1687-91.
2007: Thielen Joshua L; Volzing Katherine G; Collier Lara S; Green Laura E; Largaespada David A; Marker Paul C
Markers of prostate region-specific epithelial identity define anatomical locations in the mouse prostate that are molecularly similar to human prostate cancers.
Differentiation; research in biological diversity 2007;75(1):49-61.
2007: Collier Lara S; Largaespada David A
Transposable elements and the dynamic somatic genome.
Genome biology 2007;8 Suppl 1():S5.
2007: Collier Lara S; Largaespada David A
Transposons for cancer gene discovery: Sleeping Beauty and beyond.
Genome biology 2007;8 Suppl 1():S15.
2006: Balciunas Darius; Wangensteen Kirk J; Wilber Andrew; Bell Jason; Geurts Aron; Sivasubbu Sridhar; Wang Xin; Hackett Perry B; Largaespada David A; McIvor R Scott; Ekker Stephen C
Harnessing a high cargo-capacity transposon for genetic applications in vertebrates.
PLoS genetics 2006;2(11):e169.
2006: Geurts Aron M; Collier Lara S; Geurts Jennifer L; Oseth Leann L; Bell Matthew L; Mu David; Lucito Robert; Godbout Susan A; Green Laura E; Lowe Scott W; Hirsch Betsy A; Leinwand Leslie A; Largaespada David A
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers.
PLoS genetics 2006;2(9):e156.
2006: Yin Bin; Kogan Scott C; Dickins Ross A; Lowe Scott W; Largaespada David A
Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia.
Experimental hematology 2006;34(5):631-41.
2006: Wilber Andrew; Frandsen Joel L; Geurts Jennifer L; Largaespada David A; Hackett Perry B; McIvor R Scott
RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(3):625-30.
2006: Score Paul R; Belur Lalitha R; Frandsen Joel L; Geurts Jennifer L; Yamaguchi Tomoyuki; Somia Nikunj V; Hackett Perry B; Largaespada David A; McIvor R Scott
Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(3):617-24.
2006: Collier Lara S; Largaespada David A
Transforming science: cancer gene identification.
Current opinion in genetics & development 2006;16(1):23-9.
2006: Yin B; Morgan K; Hasz D E; Mao Z; Largaespada D A
Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(1):151-4.
2006: Geurts Aron M; Wilber Andrew; Carlson Corey M; Lobitz Paul D; Clark Karl J; Hackett Perry B; McIvor R Scott; Largaespada David A
Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon.
BMC biotechnology 2006;6():30.
2006: Geurts Aron M; Hackett Christopher S; Bell Jason B; Bergemann Tracy L; Collier Lara S; Carlson Corey M; Largaespada David A; Hackett Perry B
Structure-based prediction of insertion-site preferences of transposons into chromosomes.
Nucleic acids research 2006;34(9):2803-11.
2005: Ohlfest John R; Freese Andrew B; Largaespada David A
Nonviral vectors for cancer gene therapy: prospects for integrating vectors and combination therapies.
Current gene therapy 2005;5(6):629-41.
2005: Starr Timothy K; Largaespada David A
Cancer gene discovery using the Sleeping Beauty transposon.
Cell cycle (Georgetown, Tex.) 2005;4(12):1744-8.
2005: Carlson Corey M; Frandsen Joel L; Kirchhof Nicole; McIvor R Scott; Largaespada David A
Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17059-64.
2005: Collier Lara S; Largaespada David A
Hopping around the tumor genome: transposons for cancer gene discovery.
Cancer research 2005;65(21):9607-10.
2005: Ohlfest John R; Demorest Zachary L; Motooka Yasuhiko; Vengco Isabelita; Oh Seunguk; Chen Eleanor; Scappaticci Frank A; Saplis Rachel J; Ekker Stephen C; Low Walter C; Freese Andrew B; Largaespada David A
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(5):778-88.
2005: Park Chang Won; Kren Betsy T; Largaespada David A; Steer Clifford J
DNA methylation of Sleeping Beauty with transposition into the mouse genome.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(8):763-76.
2005: Wiesner Stephen M; Jones Jamie M; Hasz Diane E; Largaespada David A
Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse.
Blood 2005;106(3):1054-62.
2005: Collier Lara S; Carlson Corey M; Ravimohan Shruthi; Dupuy Adam J; Largaespada David A
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse.
Nature 2005;436(7048):272-6.
2005: Dupuy Adam J; Akagi Keiko; Largaespada David A; Copeland Neal G; Jenkins Nancy A
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.
Nature 2005;436(7048):221-6.
2005: Carlson Corey M; Largaespada David A
Insertional mutagenesis in mice: new perspectives and tools.
Nature reviews. Genetics 2005;6(7):568-80.
2005: Ohlfest John R; Frandsen Joel L; Fritz Sabine; Lobitz Paul D; Perkinson Scott G; Clark Karl J; Nelsestuen Gary; Key Nigel S; McIvor R Scott; Hackett Perry B; Largaespada David A
Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system.
Blood 2005;105(7):2691-8.
2005: Liu Geyi; Geurts Aron M; Yae Kojiro; Srinivasan A R; Fahrenkrug Scott C; Largaespada David A; Takeda Junji; Horie Kyoji; Olson Wilma K; Hackett Perry B
Target-site preferences of Sleeping Beauty transposons.
Journal of molecular biology 2005;346(1):161-73.
2005: Hackett Perry B; Ekker Stephen C; Largaespada David A; McIvor R Scott
Sleeping beauty transposon-mediated gene therapy for prolonged expression.
Advances in genetics 2005;54():189-232.
2004: Ohlfest John R; Lobitz Paul D; Perkinson Scott G; Largaespada David A
Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(2):260-8.
2003: Largaespada David A
Generating and manipulating transgenic animals using transposable elements.
Reproductive biology and endocrinology : RB&E 2003;1():80.
2003: Carlson Corey M; Dupuy Adam J; Fritz Sabine; Roberg-Perez Kevin J; Fletcher Colin F; Largaespada David A
Transposon mutagenesis of the mouse germline.
Genetics 2003;165(1):243-56.
2003: Belur Lalitha R; Frandsen Joel L; Dupuy Adam J; Ingbar David H; Largaespada David A; Hackett Perry B; Scott McIvor R
Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):501-7.
2003: Largaespada David A
A bad rap: Rap1 signaling and oncogenesis.
Cancer cell 2003;4(1):3-4.
2003: Geurts Aron M; Yang Ying; Clark Karl J; Liu Geyi; Cui Zongbin; Dupuy Adam J; Bell Jason B; Largaespada David A; Hackett Perry B
Gene transfer into genomes of human cells by the sleeping beauty transposon system.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(1):108-17.
2003: Roberg-Perez Kevin; Carlson Corey M; Largaespada David A
MTID: a database of Sleeping Beauty transposon insertions in mice.
Nucleic acids research 2003;31(1):78-81.
2003: Keene C Dirk; Ortiz-Gonzalez Xilma R; Jiang Yuehua; Largaespada David A; Verfaillie Catherine M; Low Walter C
Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos.
Cell transplantation 2003;12(3):201-13.
2003: Largaespada David A
Genetically modified mice in cancer research.
Methods in molecular biology (Clifton, N.J.) 2003;209():311-32.
2002: Rizvi Tilat A; Huang Yuan; Sidani Amer; Atit Radhika; Largaespada David A; Boissy Raymond E; Ratner Nancy
A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(22):9831-40.
2002: Jiang Yuehua; Jahagirdar Balkrishna N; Reinhardt R Lee; Schwartz Robert E; Keene C Dirk; Ortiz-Gonzalez Xilma R; Reyes Morayma; Lenvik Todd; Lund Troy; Blackstad Mark; Du Jingbo; Aldrich Sara; Lisberg Aaron; Low Walter C; Largaespada David A; Verfaillie Catherine M
Pluripotency of mesenchymal stem cells derived from adult marrow.
Nature 2002;418(6893):41-9.
2002: Dupuy Adam J; Clark Karl; Carlson Corey M; Fritz Sabine; Davidson Ann E; Markley Karra M; Finley Ken; Fletcher Colin F; Ekker Stephen C; Hackett Perry B; Horn Sandra; Largaespada David A
Mammalian germ-line transgenesis by transposition.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4495-9.
2002: Himmel Karen L; Bi Feng; Shen Haifa; Jenkins Nancy A; Copeland Neal G; Zheng Yi; Largaespada David A
Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias.
The Journal of biological chemistry 2002;277(16):13463-72.
2001: Blaydes S M; Kogan S C; Truong B T; Gilbert D J; Jenkins N A; Copeland N G; Largaespada D A; Brannan C I
Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia.
Journal of virology 2001;75(19):9427-34.
2001: Acar H; Caliskan U U; Kaynak M; Yildirim M S; Largaespada D A
Hyperdiploid karyotype in a childhood MDS patient.
Clinical and laboratory haematology 2001;23(4):255-8.
2001: Fujino T; Yamazaki Y; Largaespada D A; Jenkins N A; Copeland N G; Hirokawa K; Nakamura T
Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes.
Experimental hematology 2001;29(7):856-63.
2001: Dupuy A J; Fritz S; Largaespada D A
Transposition and gene disruption in the male germline of the mouse.
Genesis (New York, N.Y. : 2000) 2001;30(2):82-8.
2001: Shannon K M; Le Beau M M; Largaespada D A; Killeen N
Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse.
Seminars in cancer biology 2001;11(3):191-200.
2001: Dupuy A J; Morgan K; von Lintig F C; Shen H; Acar H; Hasz D E; Jenkins N A; Copeland N G; Boss G R; Largaespada D A
Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia.
The Journal of biological chemistry 2001;276(15):11804-11.
2001: Largaespada D A
Haploinsufficiency for tumor suppression: the hazards of being single and living a long time.
The Journal of experimental medicine 2001;193(4):F15-8.
2001: Acar H; Caliskan U; Demirel S; Largaespada D A
Micronucleus incidence and their chromosomal origin related to therapy in acute lymphoblastic leukemia (ALL) patients: detection by micronucleus and FISH techniques.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(5):341-7.
2000: Park L S; Martin U; Garka K; Gliniak B; Di Santo J P; Muller W; Largaespada D A; Copeland N G; Jenkins N A; Farr A G; Ziegler S F; Morrissey P J; Paxton R; Sims J E
Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.
The Journal of experimental medicine 2000;192(5):659-70.
2000: Acar H; Copeland N G; Gilbert D J; Jenkins N A; Largaespada D A
Detection of integrated murine leukemia viruses in a mouse model of acute myeloid leukemia by fluorescence in situ hybridization combined with tyramide signal amplification.
Cancer genetics and cytogenetics 2000;121(1):44-51.
2000: Britton R A; Chen S M; Wallis D; Koeuth T; Powell B S; Shaffer L G; Largaespada D; Jenkins N A; Copeland N G; Court D L; Lupski J R
Isolation and preliminary characterization of the human and mouse homologues of the bacterial cell cycle gene era.
Genomics 2000;67(1):78-82.
2000: Largaespada D A
Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(7):1174-84.
2000: Nakamura T; Yamazaki Y; Saiki Y; Moriyama M; Largaespada D A; Jenkins N A; Copeland N G
Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product.
Molecular and cellular biology 2000;20(9):3178-86.
2000: Tian E; Sawyer J R; Largaespada D A; Jenkins N A; Copeland N G; Shaughnessy J D
Evi27 encodes a novel membrane protein with homology to the IL17 receptor.
Oncogene 2000;19(17):2098-109.
1999: Li J; Shen H; Himmel K L; Dupuy A J; Largaespada D A; Nakamura T; Shaughnessy J D; Jenkins N A; Copeland N G
Leukaemia disease genes: large-scale cloning and pathway predictions.
Nature genetics 1999;23(3):348-53.
1999: Shaughnessy J D; Largaespada D A; Tian E; Fletcher C F; Cho B C; Vyas P; Jenkins N A; Copeland N G
Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1.
Oncogene 1999;18(12):2069-84.
1997: Bedell M A; Largaespada D A; Jenkins N A; Copeland N G
Mouse models of human disease. Part II: recent progress and future directions.
Genes & development 1997;11(1):11-43.
1996: Largaespada D A; Jackson M W; Thompson N E; Kaehler D A; Byrd L G; Mushinski J F
The ABL-MYC retrovirus generates antigen-specific plasmacytomas by in vitro infection of activated B lymphocytes from spleen and other murine lymphoid organs.
Journal of immunological methods 1996;197(1-2):85-95.
1996: Sutton J; Costa R; Klug M; Field L; Xu D; Largaespada D A; Fletcher C F; Jenkins N A; Copeland N G; Klemsz M; Hromas R
Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.
The Journal of biological chemistry 1996;271(38):23126-33.
1996: Taylor G A; Jeffers M; Largaespada D A; Jenkins N A; Copeland N G; Woude G F
Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma.
The Journal of biological chemistry 1996;271(34):20399-405.
1996: Nakamura T; Largaespada D A; Lee M P; Johnson L A; Ohyashiki K; Toyama K; Chen S J; Willman C L; Chen I M; Feinberg A P; Jenkins N A; Copeland N G; Shaughnessy J D
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.
Nature genetics 1996;12(2):154-8.
1996: Nakamura T; Largaespada D A; Shaughnessy J D; Jenkins N A; Copeland N G
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias.
Nature genetics 1996;12(2):149-53.
1996: Largaespada D A; Brannan C I; Jenkins N A; Copeland N G
Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Nature genetics 1996;12(2):137-43.
1996: Largaespada D A; Brannan C I; Shaughnessy J D; Jenkins N A; Copeland N G
The neurofibromatosis type 1 (NF1) tumor suppressor gene and myeloid leukemia.
Current topics in microbiology and immunology 1996;211():233-9.
1995: Cho B C; Shaughnessy J D; Largaespada D A; Bedigian H G; Buchberg A M; Jenkins N A; Copeland N G
Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas.
Journal of virology 1995;69(11):7138-46.
1995: Largaespada D A; Shaughnessy J D; Jenkins N A; Copeland N G
Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels.
Journal of virology 1995;69(8):5095-102.
1994: Kelner G S; Kennedy J; Bacon K B; Kleyensteuber S; Largaespada D A; Jenkins N A; Copeland N G; Bazan J F; Moore K W; Schall T J
Lymphotactin: a cytokine that represents a new class of chemokine.
Science (New York, N.Y.) 1994;266(5189):1395-9.
1993: Brott B K; Alessandrini A; Largaespada D A; Copeland N G; Jenkins N A; Crews C M; Erikson R L
MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(11):921-9.
1993: Webb G C; Jenkins N A; Largaespada D A; Copeland N G; Fernandez C S; Bowtell D D
Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.
Genomics 1993;18(1):14-9.
1993: Rawlings D J; Saffran D C; Tsukada S; Largaespada D A; Grimaldi J C; Cohen L; Mohr R N; Bazan J F; Howard M; Copeland N G
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice.
Science (New York, N.Y.) 1993;261(5119):358-61.
1993: McKenzie A N; Li X; Largaespada D A; Sato A; Kaneda A; Zurawski S M; Doyle E L; Milatovich A; Francke U; Copeland N G
Structural comparison and chromosomal localization of the human and mouse IL-13 genes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(12):5436-44.
1992: Largaespada D A; Kaehler D A; Mishak H; Weissinger E; Potter M; Mushinski J F; Risser R
A retrovirus that expresses v-abl and c-myc oncogenes rapidly induces plasmacytomas.
Oncogene 1992;7(4):811-9.
1991: Weissinger E M; Mischak H; Largaespada D A; Kaehler D A; Mitchell T; Smith-Gill S J; Risser R; Mushinski J F
Induction of plasmacytomas secreting antigen-specific monoclonal antibodies with a retrovirus expressing v-abl and c-myc.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8735-9.
1990: Largaespada D; Kaehler D; Weissinger E; Mischak H; Mushinski F; Risser R
The activity of an ABL-MYC retrovirus in fibroblast cell lines and in lymphocytes.
Current topics in microbiology and immunology 1990;166():91-6.
1990: Weissinger E M; Largaespada D; Smith-Gill S J; Risser R; Mushinski J F; Mischak H
A retrovirus expressing v-abl and c-myc induces plasmacytomas in 100% of adult pristane-primed BALB/c mice.
Current topics in microbiology and immunology 1990;166():121-7.

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