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Rana Singh

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Kameswaran Ravichandran; Balaiya Velmurugan; Mallikarjuna Gu; Rana Singh; Rajesh Agarwal
Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
Balaiya Velmurugan; Rana Singh; Rajesh Agarwal; Chapla Agarwal
Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
Manjinder Kaur; Balaiya Velmurugan; Alpna Tyagi; Chapla Agarwal; Rana Singh; Rajesh Agarwal
Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.

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All Publications

2010: Kameswaran Ravichandran; Balaiya Velmurugan; Mallikarjuna Gu; Rana Singh; Rajesh Agarwal
Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(18):4595-606.
2010: Balaiya Velmurugan; Rana Singh; Rajesh Agarwal; Chapla Agarwal
Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
Molecular carcinogenesis 2010;49(7):641-52.
2010: Manjinder Kaur; Balaiya Velmurugan; Alpna Tyagi; Chapla Agarwal; Rana Singh; Rajesh Agarwal
Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Neoplasia (New York, N.Y.) 2010;12(5):415-24.
2010: Subapriya Rajamanickam; Balaiya Velmurugan; Manjinder Kaur; Rana Singh; Rajesh Agarwal
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
Cancer research 2010;70(6):2368-78.
2010: Samiha Mateen; Alpna Tyagi; Chapla Agarwal; Rana Singh; Rajesh Agarwal
Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators.
Molecular carcinogenesis 2010;49(3):247-58.
2010: Balaiya Velmurugan; Rana Singh; Nidhi Kaul; Rajesh Agarwal; Chapla Agarwal
Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice.
Neoplasia (New York, N.Y.) 2010;12(1):95-102.
2009: Subapriya Rajamanickam; Manjinder Kaur; Balaiya Velmurugan; Rana Singh; Rajesh Agarwal
Silibinin suppresses spontaneous tumorigenesis in APC min/+ mouse model by modulating beta-catenin pathway.
Pharmaceutical research 2009;26(12):2558-67.
2009: Rana Singh; Rajesh Agarwal
Cosmeceuticals and silibinin.
Clinics in dermatology 2009;27(5):479-84.
2009: Srirupa Roy; Mallikarjuna Gu; Kumaraguruparan Ramasamy; Rana Singh; Chapla Agarwal; Sunitha Siriwardana; Robert A Sclafani; Rajesh Agarwal
p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
Cancer research 2009;69(3):1166-73.
2009: Rana Singh; Komal Raina; Gagan Deep; Daniel Chan; Rajesh Agarwal
Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(2):613-21.
2009: Tae Jin Kang; Sook Yeon Lee; Rana Singh; Rajesh Agarwal; Dong Sool Yim
Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells.
Acta oncologica (Stockholm, Sweden) 2009;48(6):895-900.
2009: Alpna Tyagi; Rana Singh; Kumaraguruparan Ramasamy; Komal Raina; Elizabeth F Redente; Lori D Dwyer-Nield; Richard A Radcliffe; Alvin M Malkinson; Rajesh Agarwal
Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
Cancer prevention research (Philadelphia, Pa.) 2009;2(1):74-83.
2008: Rana Singh; Komal Raina; Girish Sharma; Rajesh Agarwal
Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(23):7773-80.
2008: Balaiya Velmurugan; Rana Singh; Alpna Tyagi; Rajesh Agarwal
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
Cancer prevention research (Philadelphia, Pa.) 2008;1(5):376-84.
2008: Komal Raina; Subapriya Rajamanickam; Rana Singh; Gagan Deep; Manesh Chittezhath; Rajesh Agarwal
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.
Cancer research 2008;68(16):6822-30.
2008: Manesh Chittezhath; Gagan Deep; Rana Singh; Chapla Agarwal; Rajesh Agarwal
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
Molecular cancer therapeutics 2008;7(7):1817-26.
2008: Srirupa Roy; Rana Singh; Chapla Agarwal; Sunitha Siriwardana; Robert A Sclafani; Rajesh Agarwal
Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype.
Cell cycle (Georgetown, Tex.) 2008;7(12):1828-35.
2008: Komal Raina; Subapriya Rajamanickam; Rana Singh; Rajesh Agarwal
Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):3177-84.
2008: Tariq A Bhat; Rana Singh
Tumor angiogenesis--a potential target in cancer chemoprevention.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1334-45.
2008: Rana Singh; Mallikarjuna Gu; Rajesh Agarwal
Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Cancer research 2008;68(6):2043-50.
2008: Rana Singh; Alpna Tyagi; Girish Sharma; Sarumathi Mohan; Rajesh Agarwal
Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):300-8.
2007: Alpna Tyagi; Komal Raina; Rana Singh; Mallikarjuna Gu; Chapla Agarwal; Gail Harrison; L Michael Glode; Rajesh Agarwal
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Molecular cancer therapeutics 2007;6(12 Pt 1):3248-55.
2007: Rana Singh; Gagan Deep; Marie-José Blouin; Michael N Pollak; Rajesh Agarwal
Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.
Carcinogenesis 2007;28(12):2567-74.
2007: Komal Raina; Marie-José Blouin; Rana Singh; Noreen Majeed; Gagan Deep; Leyon Varghese; L Michael Glodé; Norman M Greenberg; David Hwang; Pinchas Cohen; Michael N Pollak; Rajesh Agarwal
Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
Cancer research 2007;67(22):11083-91.
2007: Rana Singh; Rajesh Agarwal
Inducible nitric oxide synthase-vascular endothelial growth factor axis: a potential target to inhibit tumor angiogenesis by dietary agents.
Current cancer drug targets 2007;7(5):475-83.
2007: Komal Raina; Rana Singh; Rajesh Agarwal; Chapla Agarwal
Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice.
Cancer research 2007;67(12):5976-82.
2007: Mallikarjuna Gu; Rana Singh; Sivanandhan Dhanalakshmi; Chapla Agarwal; Rajesh Agarwal
Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
Cancer research 2007;67(7):3483-91.
2007: Raman Saini; Rana Singh; Pawan K Jaiwal
Agrobacterium tumefaciens mediated transfer of Phaseolus vulgaris alpha-amylase inhibitor-1 gene into mungbean Vigna radiata (L.) Wilczek using bar as selectable marker.
Plant cell reports 2007;26(2):187-98.
2006: Rajesh Agarwal; Chapla Agarwal; Haruyo Ichikawa; Rana Singh; Bharat B Aggarwal
Anticancer potential of silymarin: from bench to bed side.
Anticancer research 2006;26(6B):4457-98.
2006: Alpna Tyagi; Rana Singh; Chapla Agarwal; Rajesh Agarwal
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
Carcinogenesis 2006;27(11):2269-80.
2006: Manjinder Kaur; Rana Singh; Mallikarjuna Gu; Rajesh Agarwal; Chapla Agarwal
Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):6194-202.
2006: Rana Singh; Rajesh Agarwal
Mechanisms of action of novel agents for prostate cancer chemoprevention.
Endocrine-related cancer 2006;13(3):751-78.
2006: Mallikarjuna Gu; Rana Singh; Sivanandhan Dhanalakshmi; Sarumathi Mohan; Rajesh Agarwal
Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
Molecular cancer therapeutics 2006;5(8):2121-9.
2006: Ravikanth Veluri; Rana Singh; Zhengjie Liu; John A Thompson; Rajesh Agarwal; Chapla Agarwal
Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
Carcinogenesis 2006;27(7):1445-53.
2006: Rana Singh; Gagan Deep; Manesh Chittezhath; Manjinder Kaur; Lori D Dwyer-Nield; Alvin M Malkinson; Rajesh Agarwal
Effect of silibinin on the growth and progression of primary lung tumors in mice.
Journal of the National Cancer Institute 2006;98(12):846-55.
2006: Rana Singh; Rajesh Agarwal
Prostate cancer chemoprevention by silibinin: bench to bedside.
Molecular carcinogenesis 2006;45(6):436-42.
2006: Rana Singh; Sivanandhan Dhanalakshmi; Sarumathi Mohan; Chapla Agarwal; Rajesh Agarwal
Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells.
Molecular cancer therapeutics 2006;5(5):1145-53.
2006: Rana Singh; Rajesh Agarwal
Natural flavonoids targeting deregulated cell cycle progression in cancer cells.
Current drug targets 2006;7(3):345-54.
2006: Gagan Deep; Rana Singh; Chapla Agarwal; David Kroll; Rajesh Agarwal
Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.
Oncogene 2006;25(7):1053-69.
2006: Rana Singh; S Banerjee; P V S Kumar; RAVEESHA K.A..; A Ramesha Rao
Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibits lipid peroxidation in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2006;13(1-2):74-84.
2005: Leyon Varghese; Chapla Agarwal; Alpna Tyagi; Rana Singh; Rajesh Agarwal
Silibinin efficacy against human hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8441-8.
2005: Alpna Tyagi; Rana Singh; Chapla Agarwal; Sunitha Siriwardana; Robert A Sclafani; Rajesh Agarwal
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
Carcinogenesis 2005;26(11):1978-87.
2005: Rana Singh; Rajesh Agarwal
Mechanisms and preclinical efficacy of silibinin in preventing skin cancer.
European journal of cancer (Oxford, England : 1990) 2005;41(13):1969-79.
2005: Mallikarjuna Gu; Sivanandhan Dhanalakshmi; Sarumathi Mohan; Rana Singh; Rajesh Agarwal
Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin.
Carcinogenesis 2005;26(8):1404-13.
2005: Rana Singh; Rajesh Agarwal
Prostate cancer and inositol hexaphosphate: efficacy and mechanisms.
Anticancer research 2005;25(4):2891-903.
2005: Sivanandhan Dhanalakshmi; Chapla Agarwal; Rana Singh; Rajesh Agarwal
Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.
The Journal of biological chemistry 2005;280(21):20375-83.
2005: Mallikarjuna Gu; Sivanandhan Dhanalakshmi; Rana Singh; Rajesh Agarwal
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1344-9.
2005: Rana Singh; Puja Agrawal; Dongsool Yim; Chapla Agarwal; Rajesh Agarwal
Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate.
Carcinogenesis 2005;26(4):845-54.
2005: Rana Singh; Sivanandhan Dhanalakshmi; Chapla Agarwal; Rajesh Agarwal
Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy.
Oncogene 2005;24(7):1188-202.
2005: Dongsool Yim; Rana Singh; Chapla Agarwal; Sookyeon Lee; Hyungjoon Chi; Rajesh Agarwal
A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
Cancer research 2005;65(3):1035-44.
2005: Manjinder Kaur; Chapla Agarwal; Rana Singh; Xiangming Guan; Chandradhar Dwivedi; Rajesh Agarwal
Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release.
Carcinogenesis 2005;26(2):369-80.
2005: Bandhuvula Padmavathi; Meenakshi Upreti; Virendra Singh; A Ramesha Rao; Rana Singh; Pramod C Rath
Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor.
Nutrition and cancer 2005;51(1):59-67.
2004: Rana Singh; Mallikarjuna Gu; Girish Sharma; Sivanandhan Dhanalakshmi; Anil K Tyagi; Daniel C F Chan; Chapla Agarwal; Rajesh Agarwal
Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8641-7.
2004: Rana Singh; Rajesh Agarwal
A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer.
Mutation research 2004;555(1-2):21-32.
2004: Chapla Agarwal; Sivanandhan Dhanalakshmi; Rana Singh; Rajesh Agarwal
Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells.
Neoplasia (New York, N.Y.) 2004;6(5):646-59.
2004: Mallikarjuna Gu; Sivanandhan Dhanalakshmi; Rana Singh; Chapla Agarwal; Rajesh Agarwal
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
Cancer research 2004;64(17):6349-56.
2004: Sivanandhan Dhanalakshmi; Mallikarjuna Gu; Rana Singh; Rajesh Agarwal
Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
Carcinogenesis 2004;25(8):1459-65.
2004: Sarumathi Mohan; Sivanandhan Dhanalakshmi; Mallikarjuna Gu; Rana Singh; Rajesh Agarwal
Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells.
Biochemical and biophysical research communications 2004;320(1):183-9.
2004: Girish Sharma; Anil K Tyagi; Rana Singh; Daniel C F Chan; Rajesh Agarwal
Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells.
Breast cancer research and treatment 2004;85(1):1-12.
2004: Chapla Agarwal; Rana Singh; Sivanandhan Dhanalakshmi; Rajesh Agarwal
Anti-angiogenic efficacy of grape seed extract in endothelial cells.
Oncology reports 2004;11(3):681-5.
2004: Rana Singh; Anil K Tyagi; Sivanandhan Dhanalakshmi; Rajesh Agarwal; Chapla Agarwal
Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.
International journal of cancer. Journal international du cancer 2004;108(5):733-40.
2004: Rana Singh; Rajesh Agarwal
Prostate cancer prevention by silibinin.
Current cancer drug targets 2004;4(1):1-11.
2004: Rana Singh; Girish Sharma; Mallikarjuna Gu; Sivanandhan Dhanalakshmi; Chapla Agarwal; Rajesh Agarwal
In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):244-50.
2004: Sivanandhan Dhanalakshmi; Mallikarjuna Gu; Rana Singh; Rajesh Agarwal
Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes.
Carcinogenesis 2004;25(1):99-106.
2003: Anil K Tyagi; Chapla Agarwal; Rana Singh; Kenneth R Shroyer; L Michael Glode; Rajesh Agarwal
Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells.
Biochemical and biophysical research communications 2003;312(4):1178-84.
2003: Chapla Agarwal; Rana Singh; Sivanandhan Dhanalakshmi; Anil K Tyagi; Marianne Tecklenburg; Robert A Sclafani; Rajesh Agarwal
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
Oncogene 2003;22(51):8271-82.
2003: Girish Sharma; Rana Singh; Rajesh Agarwal
Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells.
International journal of oncology 2003;23(5):1413-8.
2003: Chapla Agarwal; Sivanandhan Dhanalakshmi; Rana Singh; Rajesh Agarwal
Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
Anticancer research 2003;23(5A):3855-61.
2003: Lin Qi; Rana Singh; Yingnian Lu; Rajesh Agarwal; Gail S Harrison; Alex Franzusoff; L Michael Glode
Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
Cancer biology & therapy 2003;2(5):526-31.
2003: Rana Singh; Girish Sharma; Sivanandhan Dhanalakshmi; Chapla Agarwal; Rajesh Agarwal
Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(9):933-9.
2003: Rana Singh; Rajesh Agarwal
Tumor angiogenesis: a potential target in cancer control by phytochemicals.
Current cancer drug targets 2003;3(3):205-17.
2003: Girish Sharma; Rana Singh; Daniel C Chan; Rajesh Agarwal
Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells.
Anticancer research 2003;23(3B):2649-55.
2003: Rana Singh; Chapla Agarwal; Rajesh Agarwal
Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
Carcinogenesis 2003;24(3):555-63.
2002: Anil K Tyagi; Rana Singh; Chapla Agarwal; Daniel C F Chan; Rajesh Agarwal
Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3512-9.
2002: Chapla Agarwal; Rana Singh; Rajesh Agarwal
Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release.
Carcinogenesis 2002;23(11):1869-76.
2002: Rana Singh; Rajesh Agarwal
Flavonoid antioxidant silymarin and skin cancer.
Antioxidants & redox signaling 2002;4(4):655-63.
2002: Rana Singh; Sivanandhan Dhanalakshmi; Anil K Tyagi; Daniel C F Chan; Chapla Agarwal; Rajesh Agarwal
Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels.
Cancer research 2002;62(11):3063-9.
2002: Rana Singh; Sivanandhan Dhanalakshmi; Rajesh Agarwal
Phytochemicals as cell cycle modulators--a less toxic approach in halting human cancers.
Cell cycle (Georgetown, Tex.) 2002;1(3):156-61.
2002: Sivanandhan Dhanalakshmi; Rana Singh; Chapla Agarwal; Rajesh Agarwal
Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis.
Oncogene 2002;21(11):1759-67.
2002: Rana Singh; Anil K Tyagi; Jifu Zhao; Rajesh Agarwal
Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis.
Carcinogenesis 2002;23(3):499-510.
2001: Rana Singh; S Banerjee; A R Rao
Modulatory influence of Andrographis paniculata on mouse hepatic and extrahepatic carcinogen metabolizing enzymes and antioxidant status.
Phytotherapy research : PTR 2001;15(5):382-90.
2000: X Zi; Rana Singh; R Agarwal
Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells.
Carcinogenesis 2000;21(12):2225-35.
2000: Rana Singh; B Padmavathi; A Ramesha Rao
Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism, antioxidant status and lipid peroxidation in mice.
Molecular and cellular biochemistry 2000;213(1-2):99-109.
2000: Rana Singh; S Banerjee; A R Rao
Effect of Aegle marmelos on biotransformation enzyme systems and protection against free-radical-mediated damage in mice.
The Journal of pharmacy and pharmacology 2000;52(8):991-1000.
2000: Rana Singh; Sivanandhan Dhanalakshmi; A Ramesha Rao
Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2000;7(3):209-19.