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Francesco Galimi

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Claudio Isella; Enzo Medico; Alfredo Mellano; Andrea Bertotti; Lorenzo Capussotti; Michele De Simone; Francesco Galimi; Consalvo Petti; Andrea Muratore
MACC1 mRNA Levels Predict Cancer Recurrence After Resection of Colorectal Cancer Liver Metastases.
S Gastaldi; G Migliardi; G Molyneux; T Perera; F Sassi; Matthew J Smalley; D Torti; Paolo Accornero; Andrea Bertotti; Carla Boccaccio; P M Comoglio; Francesco Galimi; livio trusolino
Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.
Luis Paz-Ares; Tony Sabin; Jan P van Meerbeeck; Rafal Wierzbicki; Beatrix Bálint; Susan Cottrell; Richard H de Boer; Paul De Souza; Francesco Galimi; Vincent Haddad; Yong-jiang Hei; Cheng-Pang Hsu; Yang Pan; Rodryg Ramlau
A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer.

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All Publications

2013: Claudio Isella; Enzo Medico; Alfredo Mellano; Andrea Bertotti; Lorenzo Capussotti; Michele De Simone; Francesco Galimi; Consalvo Petti; Andrea Muratore
MACC1 mRNA Levels Predict Cancer Recurrence After Resection of Colorectal Cancer Liver Metastases.
Annals of surgery 2013;257(6):1089-95.
2013: S Gastaldi; G Migliardi; G Molyneux; T Perera; F Sassi; Matthew J Smalley; D Torti; Paolo Accornero; Andrea Bertotti; Carla Boccaccio; P M Comoglio; Francesco Galimi; livio trusolino
Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.
Oncogene 2013;32(11):1428-40.
2013: Luis Paz-Ares; Tony Sabin; Jan P van Meerbeeck; Rafal Wierzbicki; Beatrix Bálint; Susan Cottrell; Richard H de Boer; Paul De Souza; Francesco Galimi; Vincent Haddad; Yong-jiang Hei; Cheng-Pang Hsu; Yang Pan; Rodryg Ramlau
A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(3):329-37.
2012: Giorgio V Scagliotti; Oleksandr Sydorenko; Ihor Vynnychenko; Bin Yao; Natividad Martinez Banaclocha; Fiona Blackhall; Tudor-Eliade Ciuleanu; Mircea Dediu; Francesco Galimi; Rinat Galiulin; Yong-Jiang Hei; Yukito Ichinose; Kaoru Kubota; Sheryl McCoy; Zsolt Papai-Szekely; Keunchil Park; Robert Pirker; David R Spigel
International, randomized, placebo-controlled, double-blind phase III study of motesanib plus carboplatin/paclitaxel in patients with advanced nonsquamous non-small-cell lung cancer: MONET1.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(23):2829-36.
2012: Giorgia Migliardi; Andrea Muratore; Alberto Pisacane; Dario Ribero; Mauro Risio; Francesco Sassi; Davide Torti; livio trusolino; Eugenia R Zanella; Michela Buscarino; Lorenzo Capussotti; Paolo M Comoglio; Federica Di Nicolantonio; Francesco Galimi; Silvia Marsoni; Paolo Massucco; Alberto Bardelli; Andrea Bertotti
Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(9):2515-25.
2012: Davide Torti; livio trusolino; Paolo M Comoglio; Francesco Galimi; Stefania Gastaldi; Timothy Perera; Francesco Sassi; Andrea Bertotti
A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
International journal of cancer. Journal international du cancer 2012;130(6):1357-66.
2012: Vincenzo Cantaluppi; Maria Chiara Deregibus; Federico Figliolini; Francesco Galimi; Davide Medica; Renato Romagnoli; Mauro Salizzoni; Giuseppe Paolo Segoloni; Ciro Tetta; Silvia Beltramo; Luigi Biancone; Giovanni Camussi
Microvesicles derived from endothelial progenitor cells enhance neoangiogenesis of human pancreatic islets.
Cell transplantation 2012;21(6):1305-20.
2011: Andrea Bertotti; Michela Buscarino; Lorenzo Capussotti; Paolo M Comoglio; Davide Corà; Federica Di Nicolantonio; Francesco Galimi; Marcello Gambacorta; Claudio Isella; Silvia Marsoni; Paolo Massucco; Enzo Medico; Giorgia Migliardi; Luca Molinaro; Andrea Muratore; Consalvo Petti; Alberto Pisacane; Dario Ribero; Mauro Risio; Nadia Russolillo; Anna Sapino; Andrea Sartore-Bianchi; Francesco Sassi; Salvatore Siena; Davide Torti; Alberto Bardelli; Emanuele Valtorta; livio trusolino
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Cancer discovery 2011;1(6):508-23.
2011: Francesco Galimi; Stefania Gastaldi; Federica Gonella; Claudio Isella; Francesca Maione; Paolo Massucco; Enzo Medico; Andrea Muratore; Gianluca Paraluppi; Timothy Perera; Alberto Pisacane; Dario Ribero; Mauro Risio; Mauro Salizzoni; Francesco Sassi; Dimitrios Siatis; Bruno Torchio; Davide Torti; livio trusolino; Lorenzo Capussotti; Paolo M Comoglio; Davide Corà; Ezio David; Maria Flavia Di Renzo; Andrea Bertotti
Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(10):3146-56.
2011: Maria Colombino; Antonio Avallone; Francesco Izzo; fabiana tatangelo; Mario Budroni; Antonio Cossu; Francesco Galimi; Pasquale Comella; Gerardo Botti; Maria Cristina Sini; Francesco Tanda; Giuseppe Palmieri
Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma.
Oncology reports 2011;25(4):899-904.
2010: Andrea Bertotti; Cecilia Bracco; Flavia Girolami; Davide Torti; Stefania Gastaldi; Francesco Galimi; Enzo Medico; Paul Elvin; Paolo M Comoglio; livio trusolino
Inhibition of Src impairs the growth of met-addicted gastric tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(15):3933-43.
2009: Andrea Bertotti; Mike F Burbridge; Stefania Gastaldi; Francesco Galimi; Davide Torti; Enzo Medico; silvia giordano; Simona Corso; Gaëlle Rolland-Valognes; Brian P Lockhart; John A Hickman; Paolo M Comoglio; livio trusolino
Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Science signaling 2009;2(100):ra80.
2009: Gregory A Dissen; Alejandro Lomniczi; Tanaya L Neff; Theodore R Hobbs; Steven G Kohama; Christopher D Kroenke; Francesco Galimi; Sergio R Ojeda
In vivo manipulation of gene expression in non-human primates using lentiviral vectors as delivery vehicles.
Methods (San Diego, Calif.) 2009;49(1):70-7.
2009: Sebastian Begemann; Francesco Galimi; Jan Karlseder
Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas.
Aging 2009;1(1):122-130.
2009: Andrea Bertotti; Mike F Burbridge; Stefania Gastaldi; Francesco Galimi; Davide Torti; Enzo Medico; silvia giordano; Simona Corso; Gaëlle Rolland-Valognes; Brian P Lockhart; John A Hickman; Paolo M Comoglio; livio trusolino
Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Science signaling 2009;2(102):er11.
2008: Vincenzo Cantaluppi; Livia Biancone; Giuseppe Mauriello Romanazzi; Federico Figliolini; Silvia Beltramo; Francesco Galimi; Maria Gavina Camboni; Elisa Deriu; Piergiulio Conaldi; Antonella Bottelli; Viviana Orlandi; Maria Beatriz Herrera; Alfonso Pacitti; Giuseppe Paolo Segoloni; Giovanni Camussi
Macrophage stimulating protein may promote tubular regeneration after acute injury.
Journal of the American Society of Nephrology : JASN 2008;19(10):1904-18.
2007: Sabine Heger; Claudio Mastronardi; Gregory A Dissen; Alejandro Lomniczi; Ricardo Cabrera; Christian L Roth; Heike Jung; Francesco Galimi; Wolfgang G Sippell; Sergio R Ojeda
Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis.
The Journal of clinical investigation 2007;117(8):2145-54.
2007: Margherita Maioli; Yolande Asara; Antonella Pintus; Stefania Ninniri; Saverio Bettuzzi; Maurizio Scaltriti; Francesco Galimi; Carlo Ventura
Creating prodynorphin-expressing stem cells alerted for a high-throughput of cardiogenic commitment.
Regenerative medicine 2007;2(2):193-202.
2007: Cecilia Garcia-Rudaz; Felix Luna; Veronica Tapia; Bredford Kerr; Lois Ma Colgin; Francesco Galimi; Gregory A Dissen; Neil Rawlings; Sergio R Ojeda
Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis.
Development (Cambridge, England) 2007;134(5):945-57.
2006: Vincenzo Cantaluppi; Livia Biancone; Giuseppe Mauriello Romanazzi; Federico Figliolini; Silvia Beltramo; M S Ninniri; Francesco Galimi; Renato Romagnoli; Alessandro Franchello; Mauro Salizzoni; Paolo Cavallo Perin; Camillo Ricordi; Giuseppe Paolo Segoloni; Giovanni Camussi
Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(11):2601-11.
2006: Giovanni Solinas; Willscott E (Scott) Naugler; Francesco Galimi; Myung-Shik Lee; Michael Karin
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16454-9.
2006: Laura L Horky; Francesco Galimi; Fred H Gage; Philip J Horner
Fate of endogenous stem/progenitor cells following spinal cord injury.
The Journal of comparative neurology 2006;498(4):525-38.
2006: Thomas Sternsdorf; Vernon T Phan; Mei Lin Maunakea; Corinne B Ocampo; Jastinder Sohal; Angela Silletto; Francesco Galimi; Michelle M Le Beau; Ronald M Evans; Scott C Kogan
Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia.
Cancer cell 2006;9(2):81-94.
2005: Francesco Galimi; Robert G Summers; Henriette van Praag; Inder M Verma; Fred H Gage
A role for bone marrow-derived cells in the vasculature of noninjured CNS.
Blood 2005;105(6):2400-2.
2005: Francesco Galimi; Enrique Saez; Jason Gall; Nien Hoong; Gerald Cho; Ronald M Evans; Inder M Verma
Development of ecdysone-regulated lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(1):142-8.
2004: Gustavo Tiscornia; Vinay Tergaonkar; Francesco Galimi; Inder M Verma
CRE recombinase-inducible RNA interference mediated by lentiviral vectors.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7347-51.
2003: Stephan Herzig; Susan Hedrick; Ianessa Morantte; Seung-Hoi Koo; Francesco Galimi; Marc Montminy
CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma.
Nature 2003;426(6963):190-3.
2003: Christian M Beauséjour; Ana Krtolica; Francesco Galimi; Masashi Narita; Scott W Lowe; Paul Yaswen; Judith Campisi
Reversal of human cellular senescence: roles of the p53 and p16 pathways.
The EMBO journal 2003;22(16):4212-22.
2003: Cristina Pastore; Gastón R Picchio; Francesco Galimi; Richard Fish; Oliver Hartley; Robin E Offord; Donald E Mosier
Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES.
Antimicrobial agents and chemotherapy 2003;47(2):509-17.
2002: Francesco Galimi; Meenakshi Noll; Yoshiyuki Kanazawa; Timothy Lax; Cindy Chen; Markus Grompe; Inder M Verma
Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors.
Blood 2002;100(8):2732-6.
2002: Francesco Galimi; Inder M Verma
Opportunities for the use of lentiviral vectors in human gene therapy.
Current topics in microbiology and immunology 2002;261():245-54.
2001: Francesco Galimi; E Cottone; Elisa Vigna; Nicolò Arena; Carla Boccaccio; silvia giordano; Luigi Naldini; paolo comoglio
Hepatocyte growth factor is a regulator of monocyte-macrophage function.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):1241-7.
1996: Maria Grano; Francesco Galimi; G Zambonin; Silvia Colucci; E Cottone; A Z Zallone; paolo comoglio
Hepatocyte growth factor is a coupling factor for osteoclasts and osteoblasts in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7644-8.
1996: Andrea Graziani; Francesco Galimi; E Medico; E Cottone; Daniela Gramaglia; Carla Boccaccio; paolo comoglio
The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.
The Journal of biological chemistry 1996;271(12):6590-3.
1995: L Naldini; Elisa Vigna; Alberto Bardelli; Antonia Follenzi; Francesco Galimi; paolo comoglio
Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction.
The Journal of biological chemistry 1995;270(2):603-11.
1994: Francesco Galimi; Gian Paolo Bagnara; Laura Bonsi; E Cottone; Antonia Follenzi; A Simeone; paolo comoglio
Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors.
The Journal of cell biology 1994;127(6 Pt 1):1743-54.
1994: F Negro; M Papotti; D Pacchioni; Francesco Galimi; Ferruccio Bonino; G Bussolati
Detection of human androgen receptor mRNA in hepatocellular carcinoma by in situ hybridisation.
Liver 1994;14(4):213-9.
1994: Carla Boccaccio; Giovanni Gaudino; Giovanna Gambarotta; Francesco Galimi; paolo comoglio
Hepatocyte growth factor (HGF) receptor expression is inducible and is part of the delayed-early response to HGF.
The Journal of biological chemistry 1994;269(17):12846-51.
1993: Francesco Galimi; Maria Felice Brizzi; paolo comoglio
The hepatocyte growth factor and its receptor.
Stem cells (Dayton, Ohio) 1993;11 Suppl 2():22-30.
1993: silvia giordano; Z Zhen; E Medico; Giovanni Gaudino; Francesco Galimi; paolo comoglio
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):649-53.