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Patrik Brundin
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69
Björklund, Anders
33
Lindvall, Olle
27
Petersén, Asa
25
Li, Jia-Yi
18
Hansson, Oskar
17
Isacson, Ole
16
Rehncrona, Stig
12
Björkqvist, Maria
11
Castilho, Roger
10
Duan, WM
10
Emgård, Mia
10
Odin, P
10
Mohapel, Paul
10
Roybon, Laurent
9
Rothwell, John
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All Publications
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2009: Smith Ruben; Bacos Karl; Fedele Valentina; Soulet Denis; Walz Helena A; Obermüller Stefanie; Lindqvist Anders; Björkqvist Maria; Klein Pontus; Onnerfjord Patrik; Brundin Patrik; Mulder Hindrik; Li Jia-Yi
Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion.
Human molecular genetics 2009;18(20):3942-54.
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2009: Deierborg Tomas; Staflin Karin; Pesic Jelena; Roybon Laurent; Brundin Patrik; Lundberg Cecilia
Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries.
Experimental neurology 2009;219(1):363-7.
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2009: Lane E L; Vercammen L; Cenci M A; Brundin P
Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats.
Experimental neurology 2009;219(1):355-8.
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2009: Maynard Christa J; Böttcher Claudia; Ortega Zaira; Smith Ruben; Florea Bogdan I; Díaz-Hernández Miguel; Brundin Patrik; Overkleeft Hermen S; Li Jia-Yi; Lucas Jose J; Dantuma Nico P
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):13986-91.
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2009: van der Burg Jorien M M; Björkqvist Maria; Brundin Patrik
Beyond the brain: widespread pathology in Huntington's disease.
Lancet neurology 2009;8(8):765-74.
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2009: Lane Emma Louise; Brundin Patrik; Cenci M Angela
Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease.
Neurobiology of disease 2009;35(1):42-51.
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2009: Roybon Laurent; Deierborg Tomas; Brundin Patrik; Li Jia-Yi
Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis.
The European journal of neuroscience 2009;29(2):232-43.
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2009: Kordower Jeffrey H; Brundin Patrik
Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(1):254.
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2009: Khoshnan Ali; Ko Jan; Tescu Simona; Brundin Patrick; Patterson Paul H
IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin.
PloS one 2009;4(6):e5768.
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2009: Roybon Laurent; Hjalt Tord; Stott Simon; Guillemot Francois; Li Jia-Yi; Brundin Patrik
Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis.
PloS one 2009;4(3):e4779.
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2008: Fountaine Timothy M; Venda Lara Lourenco; Warrick Nicholas; Christian Helen C; Brundin Patrik; Channon Keith M; Wade-Martins Richard
The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons.
The European journal of neuroscience 2008;28(12):2459-73.
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2008: Aziz N A; van der Burg J M M; Landwehrmeyer G B; Brundin P; Stijnen T; Roos R A C
Weight loss in Huntington disease increases with higher CAG repeat number.
Neurology 2008;71(19):1506-13.
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2008: Lane E L; Soulet D; Vercammen L; Cenci M A; Brundin P
Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease.
Neurobiology of disease 2008;32(2):220-8.
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2008: Brundin Patrik; Li Jia-Yi; Holton Janice L; Lindvall Olle; Revesz Tamas
Research in motion: the enigma of Parkinson's disease pathology spread.
Nature reviews. Neuroscience 2008;9(10):741-5.
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2008: Björkqvist Maria; Wild Edward J; Thiele Jenny; Silvestroni Aurelio; Andre Ralph; Lahiri Nayana; Raibon Elsa; Lee Richard V; Benn Caroline L; Soulet Denis; Magnusson Anna; Woodman Ben; Landles Christian; Pouladi Mahmoud A; Hayden Michael R; Khalili-Shirazi Azadeh; Lowdell Mark W; Brundin Patrik; Bates Gillian P; Leavitt Blair R; Möller Thomas; Tabrizi Sarah J
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
The Journal of experimental medicine 2008;205(8):1869-77.
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2008: Deierborg Tomas; Soulet Denis; Roybon Laurent; Hall Vanessa; Brundin Patrik
Emerging restorative treatments for Parkinson's disease.
Progress in neurobiology 2008;85(4):407-32.
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2008: Correia Ana Sofia; Anisimov Sergey V; Li Jia-Yi; Brundin Patrik
Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20.
Frontiers in neuroscience 2008;2(1):26-34.
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2008: Wood Nigel I; Goodman Anna O G; van der Burg Jorien M M; Gazeau Véronique; Brundin Patrik; Björkqvist Maria; Petersén Asa; Tabrizi Sarah J; Barker Roger A; Morton A Jennifer
Increased thirst and drinking in Huntington's disease and the R6/2 mouse.
Brain research bulletin 2008;76(1-2):70-9.
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2008: Li Jia-Yi; Englund Elisabet; Holton Janice L; Soulet Denis; Hagell Peter; Lees Andrew J; Lashley Tammaryn; Quinn Niall P; Rehncrona Stig; Björklund Anders; Widner Håkan; Revesz Tamas; Lindvall Olle; Brundin Patrik
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
Nature medicine 2008;14(5):501-3.
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2008: Bacos Karl; Björkqvist Maria; Petersén Asa; Luts Lena; Maat-Schieman Marion L C; Roos Raymund A C; Sundler Frank; Brundin Patrik; Mulder Hindrik; Wierup Nils
Islet beta-cell area and hormone expression are unaltered in Huntington's disease.
Histochemistry and cell biology 2008;129(5):623-9.
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2008: Araújo Inês M; Gil Joana M; Carreira Bruno P; Mohapel Paul; Petersen Asa; Pinheiro Paulo S; Soulet Denis; Bahr Ben A; Brundin Patrik; Carvalho Caetana M
Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus.
Journal of neurochemistry 2008;105(3):666-76.
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2008: Roybon Laurent; Hjalt Tord; Christophersen Nicolaj S; Li Jia-Yi; Brundin Patrik
Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(14):3644-56.
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2008: Li Jia-Yi; Christophersen Nicolaj S; Hall Vanessa; Soulet Denis; Brundin Patrik
Critical issues of clinical human embryonic stem cell therapy for brain repair.
Trends in neurosciences 2008;31(3):146-53.
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2008: Zuchner T; Brundin P
Mutant huntingtin can paradoxically protect neurons from death.
Cell death and differentiation 2008;15(3):435-42.
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2008: Morizane Asuka; Li Jia-Yi; Brundin Patrik
From bench to bed: the potential of stem cells for the treatment of Parkinson's disease.
Cell and tissue research 2008;331(1):323-36.
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2008: van der Burg Jorien M M; Bacos Karl; Wood Nigel I; Lindqvist Andreas; Wierup Nils; Woodman Ben; Wamsteeker Jaclyn I; Smith Ruben; Deierborg Tomas; Kuhar Michael J; Bates Gillian P; Mulder Hindrik; Erlanson-Albertsson Charlotte; Morton A Jennifer; Brundin Patrik; Petersén Asa; Björkqvist Maria
Increased metabolism in the R6/2 mouse model of Huntington's disease.
Neurobiology of disease 2008;29(1):41-51.
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2008: Leist Marcel; Bremer Susanne; Brundin Patrik; Hescheler Juergen; Kirkeby Agnete; Krause Karl-Heinz; Poerzgen Peter; Puceat Michel; Schmidt Mathias; Schrattenholz Andre; Zak Naomi B; Hentze Hannes
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy.
ALTEX : Alternativen zu Tierexperimenten 2008;25(3):163-90.
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2007: Hall Vanessa J; Li Jia-Yi; Brundin Patrik
Restorative cell therapy for Parkinson's disease: a quest for the perfect cell.
Seminars in cell & developmental biology 2007;18(6):859-69.
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2007: Smith Ruben; Klein Pontus; Koc-Schmitz Yeliz; Waldvogel Henry J; Faull Richard L M; Brundin Patrik; Plomann Markus; Li Jia-Yi
Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.
Journal of neurochemistry 2007;103(1):115-23.
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2007: Björkqvist Maria; Leavitt Blair R; Nielsen Jörgen E; Landwehrmeyer Bernhard; Ecker Daniel; Mulder Hindrik; Brundin Patrik; Petersén Asa
Cocaine- and amphetamine-regulated transcript is increased in Huntington disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(13):1952-4.
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2007: Christophersen Nicolaj S; Grønborg Mette; Petersen Thomas N; Fjord-Larsen Lone; Jørgensen Jesper R; Juliusson Bengt; Blom Nikolaj; Rosenblad Carl; Brundin Patrik
Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation.
Experimental neurology 2007;204(2):791-801.
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2007: Paul Gesine; Christophersen Nicolaj S; Raymon Heather; Kiaer Caroline; Smith Ruben; Brundin Patrik
Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line--studies in vitro and after intracerebral grafting in vivo.
Molecular and cellular neurosciences 2007;34(3):390-9.
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2007: van der Borght Karin; Brundin Patrik
Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease.
Experimental neurology 2007;204(1):473-8.
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2007: Christophersen Nicolaj Strøyer; Brundin Patrik
Large stem cell grafts could lead to erroneous interpretations of behavioral results?
Nature medicine 2007;13(2):118; author reply 118-9.
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2007: Correia Ana Sofia; Anisimov Sergey V; Roybon Laurent; Li Jia-Yi; Brundin Patrik
Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells.
Frontiers in neuroanatomy 2007;1():4.
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2007: Fahrenkrug Jan; Popovic Natalija; Georg Birgitte; Brundin Patrik; Hannibal Jens
Decreased VIP and VPAC2 receptor expression in the biological clock of the R6/2 Huntington's disease mouse.
Journal of molecular neuroscience : MN 2007;31(2):139-48.
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2007: Anisimov Sergey V; Christophersen Nicolaj S; Correia Ana S; Li Jia-Yi; Brundin Patrik
"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells.
BMC genomics 2007;8():46.
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2006: Lindqvist A; Mohapel P; Bouter B; Frielingsdorf H; Pizzo D; Brundin P; Erlanson-Albertsson C
High-fat diet impairs hippocampal neurogenesis in male rats.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(12):1385-8.
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2006: Nygren Josefine; Wieloch Tadeusz; Pesic Jelena; Brundin Patrik; Deierborg Tomas
Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatum.
Stroke; a journal of cerebral circulation 2006;37(11):2824-9.
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2006: Smith Ruben; Chung Hinfan; Rundquist Sara; Maat-Schieman Marion L C; Colgan Lesley; Englund Elisabet; Liu Yong-Jian; Roos Raymund A C; Faull Richard L M; Brundin Patrik; Li Jia-Yi
Cholinergic neuronal defect without cell loss in Huntington's disease.
Human molecular genetics 2006;15(21):3119-31.
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2006: Christophersen Nicolaj S; Meijer Xia; Jørgensen Jesper R; Englund Ulrica; Grønborg Mette; Seiger Ake; Brundin Patrik; Wahlberg Lars U
Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain.
Brain research bulletin 2006;70(4-6):457-66.
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2006: Mohapel P; Mundt-Petersen K; Brundin P; Frielingsdorf H
Working memory training decreases hippocampal neurogenesis.
Neuroscience 2006;142(3):609-13.
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2006: Westin Jenny E; Lindgren Hanna S; Gardi Jonathan; Nyengaard Jens Randel; Brundin Patrik; Mohapel Paul; Cenci M Angela
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(37):9448-61.
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2006: Brundin Patrik; Angela Cenci M; Wieloch Tadeusz
On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease.
Experimental neurology 2006;201(1):1-6.
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2006: Björkqvist M; Petersén A; Nielsen J; Ecker D; Mulder H; Hayden M R; Landwehrmeyer B; Brundin P; Leavitt B R
Cerebrospinal fluid levels of orexin-A are not a clinically useful biomarker for Huntington disease.
Clinical genetics 2006;70(1):78-9.
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2006: Brederlau Anke; Correia Ana Sofia; Anisimov Sergey V; Elmi Muna; Paul Gesine; Roybon Laurent; Morizane Asuka; Bergquist Filip; Riebe Ilse; Nannmark Ulf; Carta Manolo; Hanse Erik; Takahashi Jun; Sasai Yoshiki; Funa Keiko; Brundin Patrick; Eriksson Peter S; Li Jia-Yi
Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation.
Stem cells (Dayton, Ohio) 2006;24(6):1433-40.
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2006: Roybon Laurent; Ma Zhi; Asztely Fredrik; Fosum Anna; Jacobsen Sten Eirik W; Brundin Patrik; Li Jia-Yi
Failure of transdifferentiation of adult hematopoietic stem cells into neurons.
Stem cells (Dayton, Ohio) 2006;24(6):1594-604.
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2006: Björkqvist Maria; Petersén Asa; Bacos Karl; Isaacs Jeremy; Norlén Per; Gil Joana; Popovic Natalija; Sundler Frank; Bates Gillian P; Tabrizi Sarah J; Brundin Patrik; Mulder Hindrik
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease.
Human molecular genetics 2006;15(10):1713-21.
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2006: Popovic N; Brundin P
Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases.
International journal of pharmaceutics 2006;314(2):120-6.
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2006: Lane E L; Winkler C; Brundin P; Cenci M A
The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.
Neurobiology of disease 2006;22(2):334-45.
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2006: Paul Gesine; Ahn Young Hwan; Li Jia-Yi; Brundin Patrik
Transplantation in Parkinson's disease: The future looks bright.
Advances in experimental medicine and biology 2006;557():221-48.
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2005: Puschban Zoe; Stefanova Nadia; Petersén Asa; Winkler Christian; Brundin Patrik; Poewe Werner; Wenning Gregor K
Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy.
Brain research bulletin 2005;68(1-2):54-8.
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2005: Roybon Laurent; Brundin Patrik; Li Jia-Yi
Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes.
Experimental neurology 2005;196(2):373-80.
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2005: Smith Ruben; Petersén Asa; Bates Gillian P; Brundin Patrik; Li Jia-Yi
Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction.
Neurobiology of disease 2005;20(3):673-84.
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2005: Gil Joana M A C; Mohapel Paul; Araújo Inês M; Popovic Natalija; Li Jia-Yi; Brundin Patrik; Petersén Asa
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice.
Neurobiology of disease 2005;20(3):744-51.
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2005: Papalexi Eugenia; Persson Anna; Björkqvist Maria; Petersén Asa; Woodman Ben; Bates Gillian P; Sundler Frank; Mulder Hindrik; Brundin Patrik; Popovic Natalija
Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease.
The European journal of neuroscience 2005;22(6):1541-6.
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2005: Smith R; Brundin P; Li J-Y
Synaptic dysfunction in Huntington's disease: a new perspective.
Cellular and molecular life sciences : CMLS 2005;62(17):1901-12.
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2005: Li Jia Yi; Popovic Natalija; Brundin Patrik
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2005;2(3):447-64.
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2005: Lotharius Julie; Falsig Jeppe; van Beek Johan; Payne Sarah; Dringen Ralf; Brundin Patrik; Leist Marcel
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(27):6329-42.
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2005: Ahn Young-Hwan; Bensadoun Jean-Charles; Aebischer Patrick; Zurn Anne D; Seiger Ake; Björklund Anders; Lindvall Olle; Wahlberg Lars; Brundin Patrik; Kaminski Schierle Gabriele S
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
Brain research bulletin 2005;66(2):135-42.
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2005: Iancu Ruxandra; Mohapel Paul; Brundin Patrik; Paul Gesine
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice.
Behavioural brain research 2005;162(1):1-10.
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2005: Popovic Natalija; Maingay Matthew; Kirik Deniz; Brundin Patrik
Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes.
Experimental neurology 2005;193(1):65-74.
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2005: Araújo Inês M; Xapelli Sara; Gil Joana M A C; Mohapel Paul; Petersén Asa; Pinheiro Paulo S; Malva João O; Bahr Ben A; Brundin Patrik; Carvalho Caetana M
Proteolysis of NR2B by calpain in the hippocampus of epileptic rats.
Neuroreport 2005;16(4):393-6.
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2005: Björkqvist Maria; Fex Malin; Renström Erik; Wierup Nils; Petersén Asa; Gil Joana; Bacos Karl; Popovic Natalija; Li Jia-Yi; Sundler Frank; Brundin Patrik; Mulder Hindrik
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis.
Human molecular genetics 2005;14(5):565-74.
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2005: Brundin Lena Larsson; Brundin Patrik
[Not everything worked perfectly in Thailand]
Läkartidningen 2005;102(8):584; author reply 584.
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2005: Petersén Asa; Gil Joana; Maat-Schieman Marion L C; Björkqvist Maria; Tanila Heikki; Araújo Inês M; Smith Ruben; Popovic Natalija; Wierup Nils; Norlén Per; Li Jia-Yi; Roos Raymund A C; Sundler Frank; Mulder Hindrik; Brundin Patrik
Orexin loss in Huntington's disease.
Human molecular genetics 2005;14(1):39-47.
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2005: Correia Ana Sofia; Anisimov Sergey V; Li Jia-Yi; Brundin Patrik
Stem cell-based therapy for Parkinson's disease.
Annals of medicine 2005;37(7):487-98.
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2005: Karlsson Jenny; Petersén Asa; Gidö Gunilla; Wieloch Tadeusz; Brundin Patrik
Combining neuroprotective treatment of embryonic nigral donor tissue with mild hypothermia of the graft recipient.
Cell transplantation 2005;14(5):301-9.
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2005: Mohapel P; Frielingsdorf H; Häggblad J; Zachrisson O; Brundin P
Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions.
Neuroscience 2005;132(3):767-76.
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2004: Roybon Laurent; Christophersen Nicolaj S; Brundin Patrik; Li Jia-Yi
Stem cell therapy for Parkinson's disease: where do we stand?
Cell and tissue research 2004;318(1):261-73.
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2004: Frielingsdorf Helena; Schwarz Katherine; Brundin Patrik; Mohapel Paul
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10177-82.
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2004: Mohapel Paul; Brundin Patrik
Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia.
Parkinsonism & related disorders 2004;10(5):259-64.
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2004: Gil Joana M A C; Leist Marcel; Popovic Natalija; Brundin Patrik; Petersén Asa
Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice.
BMC neuroscience 2004;5():17.
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2003: Li Jia-Yi; Plomann Markus; Brundin Patrik
Huntington's disease: a synaptopathy?
Trends in molecular medicine 2003;9(10):414-20.
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2003: Ciechanover Aaron; Brundin Patrik
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.
Neuron 2003;40(2):427-46.
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2003: Maciel Evelise N; Kaminski Schierle Gabriele S; Hansson Oskar; Brundin Patrik; Castilho Roger F
Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents.
Experimental neurology 2003;183(2):430-7.
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2003: Emgård M; Hallin U; Karlsson J; Bahr B A; Brundin P; Blomgren K
Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: a role for protease activation.
Journal of neurochemistry 2003;86(5):1223-32.
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2003: Björklund Anders; Dunnett Stephen B; Brundin Patrik; Stoessl A Jon; Freed Curt R; Breeze Robert E; Levivier Marc; Peschanski Marc; Studer Lorenz; Barker Roger
Neural transplantation for the treatment of Parkinson's disease.
Lancet neurology 2003;2(7):437-45.
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2003: Smith Ruben; Lotharius Julie; Brundin Patrik
[Free radicals and ailing proteins--the culprits behind Parkinson disease?]
Läkartidningen 2003;100(15):1324-6, 1329-30.
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2003: Hansson Oskar; Nylandsted Jesper; Castilho Roger F; Leist Marcel; Jäättelä Marja; Brundin Patrik
Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression.
Brain research 2003;970(1-2):47-57.
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2003: Ahn Young Hwan; Emgård Mia; Brundin Patrik
Ultrastructural characterization of dissociated embryonic ventral mesencephalic tissue treated with neuroprotectants.
Cell transplantation 2003;12(3):235-41.
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2002: Lotharius Julie; Brundin Patrik
Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein.
Nature reviews. Neuroscience 2002;3(12):932-42.
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2002: Karlsson Jenny; Emgård Mia; Brundin Patrik
Comparison between survival of lazaroid-treated embryonic nigral neurons in cell suspensions, cultures and transplants.
Brain research 2002;955(1-2):268-80.
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2002: Petersén A; Puschban Z; Lotharius J; NicNiocaill B; Wiekop P; O'Connor W T; Brundin P
Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice.
Neurobiology of disease 2002;11(1):134-46.
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2002: Lotharius Julie; Brundin Patrik
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease.
Human molecular genetics 2002;11(20):2395-407.
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2002: Brundin Patrik
GDNF treatment in Parkinson's disease: time for controlled clinical trials?
Brain : a journal of neurology 2002;125(Pt 10):2149-51.
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2002: Lotharius Julie; Barg Sebastian; Wiekop Pia; Lundberg Cecilia; Raymon Heather K; Brundin Patrik
Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line.
The Journal of biological chemistry 2002;277(41):38884-94.
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2002: Hagell Peter; Piccini Paola; Björklund Anders; Brundin Patrik; Rehncrona Stig; Widner Håkan; Crabb Lesley; Pavese Nicola; Oertel Wolfgang H; Quinn Niall; Brooks David J; Lindvall Olle
Dyskinesias following neural transplantation in Parkinson's disease.
Nature neuroscience 2002;5(7):627-8.
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2002: Petersén A; Chase K; Puschban Z; DiFiglia M; Brundin P; Aronin N
Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.
Experimental neurology 2002;175(1):297-300.
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2002: Zeron Melinda M; Hansson Oskar; Chen Nansheng; Wellington Cheryl L; Leavitt Blair R; Brundin Patrik; Hayden Michael R; Raymond Lynn A
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.
Neuron 2002;33(6):849-60.
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2002: Paul Gesine; Li Jia-Yi; Brundin Patrik
Stem cells: hype or hope?
Drug discovery today 2002;7(5):295-302.
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2002: Paul Gesine; Brundin Patrik
Funding embryonic stem-cell research: will commerce counteract collaboration?
Drug discovery today 2002;7(1):22-3.
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2002: Love R M; Branton R L; Karlsson J; Brundin P; Clarke D J
Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson's disease.
Cell transplantation 2002;11(7):653-62.
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2002: Petersén Asa; Brundin Patrik
Huntington's disease: the mystery unfolds?
International review of neurobiology 2002;53():315-39.
-
2002: Emgård M; Blomgren K; Brundin P
Characterisation of cell damage and death in embryonic mesencephalic tissue: a study on ultrastructure, vital stains and protease activity.
Neuroscience 2002;115(4):1177-87.
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2001: Petersén A; Hansson O; Brundin P
[Huntington disease--yet another mad protein?]
Läkartidningen 2001;98(50):5756-8, 5761.
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2001: Hansson O; Guatteo E; Mercuri N B; Bernardi G; Li X J; Castilho R F; Brundin P
Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene.
The European journal of neuroscience 2001;14(9):1492-504.
-
2001: Petersén A; Hansson O; Puschban Z; Sapp E; Romero N; Castilho R F; Sulzer D; Rice M; DiFiglia M; Przedborski S; Brundin P
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.
The European journal of neuroscience 2001;14(9):1425-35.
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2001: Petersén A A; Larsen K E; Behr G G; Romero N; Przedborski S; Brundin P; Sulzer D
Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death.
Brain research bulletin 2001;56(3-4):331-5.
-
2001: Hansson O; Castilho R F; Korhonen L; Lindholm D; Bates G P; Brundin P
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
Journal of neurochemistry 2001;78(4):694-703.
-
2001: Hagell P; Brundin P
Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease.
Journal of neuropathology and experimental neurology 2001;60(8):741-52.
-
2001: Petersén A; Larsen K E; Behr G G; Romero N; Przedborski S; Brundin P; Sulzer D
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration.
Human molecular genetics 2001;10(12):1243-54.
-
2001: Brundin P; Dunnett S; Björklund A; Nikkhah G
Transplanted dopaminergic neurons: more or less?
Nature medicine 2001;7(5):512-3.
-
2001: Nicniocaill B; Haraldsson B; Hansson O; O'Connor W T; Brundin P
Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice.
The European journal of neuroscience 2001;13(1):206-10.
-
2000: Piccini P; Lindvall O; Björklund A; Brundin P; Hagell P; Ceravolo R; Oertel W; Quinn N; Samuel M; Rehncrona S; Widner H; Brooks D J
Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts.
Annals of neurology 2000;48(5):689-95.
-
2000: Petersen A; Hansson O; Emgård M; Brundin P
Grafting of nigral tissue hibernated with tirilazad mesylate and glial cell line-derived neurotrophic factor.
Cell transplantation 2000;9(5):577-84.
-
2000: Mundt-Petersen U; Petersén A; Emgård M; Dunnett S B; Brundin P
Caspase inhibition increases embryonic striatal graft survival.
Experimental neurology 2000;164(1):112-20.
-
2000: Hansson O; Castilho R F; Kaminski Schierle G S; Karlsson J; Nicotera P; Leist M; Brundin P
Additive effects of caspase inhibitor and lazaroid on the survival of transplanted rat and human embryonic dopamine neurons.
Experimental neurology 2000;164(1):102-11.
-
2000: Castilho R F; Hansson O; Brundin P
FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons.
Experimental neurology 2000;164(1):94-101.
-
2000: Brundin P; Pogarell O; Hagell P; Piccini P; Widner H; Schrag A; Kupsch A; Crabb L; Odin P; Gustavii B; Björklund A; Brooks D J; Marsden C D; Oertel W H; Quinn N P; Rehncrona S; Lindvall O
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease.
Brain : a journal of neurology 2000;123 ( Pt 7)():1380-90.
-
2000: Karlsson J; Emgard M; Brundin P; Burkitt M J
trans-resveratrol protects embryonic mesencephalic cells from tert-butyl hydroperoxide: electron paramagnetic resonance spin trapping evidence for a radical scavenging mechanism.
Journal of neurochemistry 2000;75(1):141-50.
-
2000: Karlsson J; Emgård M; Gidö G; Wieloch T; Brundin P
Increased survival of embryonic nigral neurons when grafted to hypothermic rats.
Neuroreport 2000;11(8):1665-8.
-
2000: Larsson L C; Czech K A; Brundin P; Widner H
Intrastriatal ventral mesencephalic xenografts of porcine tissue in rats: immune responses and functional effects.
Cell transplantation 2000;9(2):261-72.
-
2000: Brundin P; Karlsson J; Emgård M; Schierle G S; Hansson O; Petersén A; Castilho R F
Improving the survival of grafted dopaminergic neurons: a review over current approaches.
Cell transplantation 2000;9(2):179-95.
-
2000: Petersén A; Castilho R F; Hansson O; Wieloch T; Brundin P
Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons.
Brain research 2000;857(1-2):20-9.
-
2000: Mundt-Petersen U; Karlsson J; Schierle G S; Brundin P
Pretreatment with MK-801 or the lazaroid U-83836E does not enhance striatal graft survival.
Cell transplantation 2000;9(1):73-8.
-
2000: Castilho R F; Hansson O; Brundin P
Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease.
Progress in brain research 2000;127():203-31.
-
1999: Petersén A; Brundin P
Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187-induced cell death in cultured embryonic striatal neurons.
Experimental neurology 1999;160(2):402-12.
-
1999: Piccini P; Brooks D J; Björklund A; Gunn R N; Grasby P M; Rimoldi O; Brundin P; Hagell P; Rehncrona S; Widner H; Lindvall O
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient.
Nature neuroscience 1999;2(12):1137-40.
-
1999: Emgård M; Karlsson J; Hansson O; Brundin P
Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts.
Experimental neurology 1999;160(1):279-88.
-
1999: Kaminski Schierle G S; Hansson O; Ferrando-May E; Nicotera P; Brundin P; Leist M
Neuronal death in nigral grafts in the absence of poly (ADP-ribose) polymerase activation.
Neuroreport 1999;10(16):3347-51.
-
1999: Petersén A; Emgård M; Brundin P
Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival.
Brain research bulletin 1999;50(4):275-81.
-
1999: Schierle G S; Leist M; Martinou J C; Widner H; Nicotera P; Brundin P
Differential effects of Bcl-2 overexpression on fibre outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants.
The European journal of neuroscience 1999;11(9):3073-81.
-
1999: Hansson O; Petersén A; Leist M; Nicotera P; Castilho R F; Brundin P
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8727-32.
-
1999: Schierle G S; Brundin P
Excitotoxicity plays a role in the death of tyrosine hydroxylase- immunopositive nigral neurons cultured in serum-free medium.
Experimental neurology 1999;157(2):338-48.
-
1999: Hagell P; Schrag A; Piccini P; Jahanshahi M; Brown R; Rehncrona S; Widner H; Brundin P; Rothwell J C; Odin P; Wenning G K; Morrish P; Gustavii B; Björklund A; Brooks D J; Marsden C D; Quinn N P; Lindvall O
Sequential bilateral transplantation in Parkinson's disease: effects of the second graft.
Brain : a journal of neurology 1999;122 ( Pt 6)():1121-32.
-
1999: Petersén A; Mani K; Brundin P
Recent advances on the pathogenesis of Huntington's disease.
Experimental neurology 1999;157(1):1-18.
-
1999: Grasbon T; Grasbon-Frodl E M; Juliusson B; Epstein C; Brundin P; Kampik A; Ehinger B
CuZn superoxide dismutase transgenic retinal transplants.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1999;237(4):336-41.
-
1999: Brundin P; Petersén A; Hansson O
Graft survival.
Journal of neurosurgery 1999;90(4):804-6.
-
1999: Karlsson J; Love R M; Clarke D J; Brundin P
Effects of anaesthetics and lazaroid U-83836E on survival of transplanted rat dopaminergic neurones.
Brain research 1999;821(2):546-50.
-
1999: Sanberg P R; Brundin P
Cell transplantation and neuroscience.
Cell transplantation 1999;8(1):3-6.
-
1999: Schierle G S; Hansson O; Leist M; Nicotera P; Widner H; Brundin P
Caspase inhibition reduces apoptosis and increases survival of nigral transplants.
Nature medicine 1999;5(1):97-100.
-
1999: Kaminski Schierle G S; Hansson O; Brundin P
Flunarizine improves the survival of grafted dopaminergic neurons.
Neuroscience 1999;94(1):17-20.
-
1998: Brundin P; Björklund A
Survival of expanded dopaminergic precursors is critical for clinical trials.
Nature neuroscience 1998;1(7):537.
-
1998: Karlsson J; Emgârd M; Rosenblad C; Brundin P
Treatment with the spin-trap agent alpha-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons.
Brain research 1998;805(1-2):155-68.
-
1998: Duan W M; Widner H; Cameron R M; Brundin P
Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat.
The European journal of neuroscience 1998;10(8):2595-606.
-
1998: Schierle G S; Karlsson J; Brundin P
MK-801 does not enhance dopaminergic cell survival in embryonic nigral grafts.
Neuroreport 1998;9(7):1313-6.
-
1998: Nakao N; Brundin P
Neurodegeneration and glutamate induced oxidative stress.
Progress in brain research 1998;116():245-63.
-
1997: Duan W M; Cameron R M; Brundin P; Widner H
Rat intrastriatal neural allografts challenged with skin allografts at different time points.
Experimental neurology 1997;148(1):334-47.
-
1997: Othberg A; Keep M; Brundin P; Lindvall O
Tirilazad mesylate improves survival of rat and human embryonic mesencephalic neurons in vitro.
Experimental neurology 1997;147(2):498-502.
-
1997: Wenning G K; Odin P; Morrish P; Rehncrona S; Widner H; Brundin P; Rothwell J C; Brown R; Gustavii B; Hagell P; Jahanshahi M; Sawle G; Björklund A; Brooks D J; Marsden C D; Quinn N P; Lindvall O
Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease.
Annals of neurology 1997;42(1):95-107.
-
1997: Barkats M; Nakao N; Grasbon-Frodl E M; Bilang-Bleuel A; Revah F; Mallet J; Brundin P
Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase.
Neuroscience 1997;78(3):703-13.
-
1997: Emgård-Mattson M; Karlsson J; Nakao N; Brundin P
Addition of lateral ganglionic eminence to rat mesencephalic grafts affects fiber outgrowth but does not enhance function.
Cell transplantation 1997;6(3):277-86.
-
1997: Duan W M; Brundin P; Widner H
Addition of allogeneic spleen cells causes rejection of intrastriatal embryonic mesencephalic allografts in the rat.
Neuroscience 1997;77(2):599-609.
-
1997: Nakao N; Brundin P
Effects of alpha-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid.
Neuroscience 1997;76(3):749-61.
-
1997: Grasbon-Frodl E M; Brundin P
Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1997;113(1):138-43.
-
1997: Grasbon-Frodl E M; Nakao N; Lindvall O; Brundin P
Developmental features of human striatal tissue transplanted in a rat model of Huntington's disease.
Neurobiology of disease 1997;3(4):299-311.
-
1996: Nakao N; Grasbon-Frodl E M; Widner H; Brundin P
DARPP-32-rich zones in grafts of lateral ganglionic eminence govern the extent of functional recovery in skilled paw reaching in an animal model of Huntington's disease.
Neuroscience 1996;74(4):959-70.
-
1996: Grasbon-Frodl E M; Andersson A; Brundin P
Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion.
Journal of neurochemistry 1996;67(4):1653-60.
-
1996: Nakao N; Grasbon-Frodl E M; Widner H; Brundin P
Antioxidant treatment protects striatal neurons against excitotoxic insults.
Neuroscience 1996;73(1):185-200.
-
1996: Grasbon-Frodl E M; Nakao N; Lindvall O; Brundin P
Phenotypic development of the human embryonic striatal primordium: a study of cultured and grafted neurons from the lateral and medial ganglionic eminences.
Neuroscience 1996;73(1):171-83.
-
1996: Brundin P; Fricker R A; Nakao N
Paucity of P-zones in striatal grafts prohibit commencement of clinical trials in Huntington's disease.
Neuroscience 1996;71(3):895-97.
-
1996: Duan W M; Brundin P; Grasbon-Frodl E M; Widner H
Methylprednisolone prevents rejection of intrastriatal grafts of xenogeneic embryonic neural tissue in adult rats.
Brain research 1996;712(2):199-212.
-
1996: Nakao N; Odin P; Lindvall O; Brundin P
Differential trophic effects of basic fibroblast growth factor, insulin-like growth factor-1, and neurotrophin-3 on striatal neurons in culture.
Experimental neurology 1996;138(1):144-57.
-
1996: Grasbon-Frodl E M; Nakao N; Brundin P
The lazaroid U-83836E improves the survival of rat embryonic mesencephalic tissue stored at 4 degrees C and subsequently used for cultures or intracerebral transplantation.
Brain research bulletin 1996;39(6):341-7.
-
1996: Grabowski M; Johansson B B; Brundin P
Fetal neocortical grafts placed in brain infarcts do not improve paw-reaching deficits in adult spontaneously hypertensive rats.
Acta neurochirurgica. Supplement 1996;66():68-72.
-
1995: Nakao N; Brundin P; Funa K; Lindvall O; Odin P
Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro.
Brain research. Developmental brain research 1995;90(1-2):92-101.
-
1995: Frodl E M; Sauer H; Lindvall O; Brundin P
Effects of hibernation or cryopreservation on the survival and integration of striatal grafts placed in the ibotenate-lesioned rat caudate-putamen.
Cell transplantation 1995;4(6):571-7.
-
1995: Grabowski M; Johansson B B; Brundin P
Neocortical grafts placed in the infarcted brain of adult rats: few or no efferent fibers grow from transplant to host.
Experimental neurology 1995;134(2):273-6.
-
1995: Nakao N; Frodl E M; Widner H; Carlson E; Eggerding F A; Epstein C J; Brundin P
Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease.
Nature medicine 1995;1(3):226-31.
-
1995: Duan W M; Widner H; Frodl E M; Brundin P
Immune reactions following systemic immunization prior or subsequent to intrastriatal transplantation of allogeneic mesencephalic tissue in adult rats.
Neuroscience 1995;64(3):629-41.
-
1995: Duan W M; Widner H; Brundin P
Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1995;104(2):227-42.
-
1994: Nakao N; Frodl E M; Duan W M; Widner H; Brundin P
Lazaroids improve the survival of grafted rat embryonic dopamine neurons.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12408-12.
-
1994: Frodl E M; Nakao N; Brundin P
Lazaroids improve the survival of cultured rat embryonic mesencephalic neurones.
Neuroreport 1994;5(17):2393-6.
-
1994: Frodl E M; Duan W M; Sauer H; Kupsch A; Brundin P
Human embryonic dopamine neurons xenografted to the rat: effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function.
Brain research 1994;647(2):286-98.
-
1994: Grabowski M; Johansson B B; Brundin P
Survival of fetal neocortical grafts implanted in brain infarcts of adult rats: the influence of postlesion time and age of donor tissue.
Experimental neurology 1994;127(1):126-36.
-
1994: Nakao N; Odin P; Brundin P
Selective sub-dissection of the striatal primordium for cultures affects the yield of DARPP-32-containing neurones.
Neuroreport 1994;5(9):1081-4.
-
1994: Lindvall O; Sawle G; Widner H; Rothwell J C; Björklund A; Brooks D; Brundin P; Frackowiak R; Marsden C D; Odin P
Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease.
Annals of neurology 1994;35(2):172-80.
-
1994: Nakao N; Brundin P; Funa K; Lindvall O; Odin P
Platelet-derived growth factor exerts trophic effects on rat striatal DARPP-32-containing neurons in culture.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1994;101(2):291-6.
-
1993: Duan W M; Widner H; Björklund A; Brundin P
Sequential intrastriatal grafting of allogeneic embryonic dopamine-rich neuronal tissue in adult rats: will the second graft be rejected?
Neuroscience 1993;57(2):261-74.
-
1993: Sauer H; Fischer W; Nikkhah G; Wiegand S J; Brundin P; Lindsay R M; Björklund A
Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts.
Brain research 1993;626(1-2):37-44.
-
1993: Grabowski M; Brundin P; Johansson B B
Functional integration of cortical grafts placed in brain infarcts of rats.
Annals of neurology 1993;34(3):362-8.
-
1993: Widner H; Brundin P
Sequential intracerebral transplantation of allogeneic and syngeneic fetal dopamine-rich neuronal tissue in adult rats: will the first graft be rejected?
Cell transplantation 1993;2(4):307-17.
-
1993: Grabowski M; Brundin P; Johansson B B
Paw-reaching, sensorimotor, and rotational behavior after brain infarction in rats.
Stroke; a journal of cerebral circulation 1993;24(6):889-95.
-
1993: Smits A; Odin P; Duan W M; Brundin P; Widner H; Heldin C H; Lindvall O; Funa K
Expression of platelet-derived growth factor in and around intrastriatal embryonic mesencephalic grafts.
Cell transplantation 1993;2(2):151-62.
-
1993: Widner H; Tetrud J; Rehncrona S; Snow B J; Brundin P; Björklund A; Lindvall O; Langston J W
Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism.
Advances in neurology 1993;60():729-33.
-
1993: Nikkhah G; Odin P; Smits A; Tingström A; Othberg A; Brundin P; Funa K; Lindvall O
Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;92(3):516-23.
-
1992: Grabowski M; Christofferson R H; Brundin P; Johansson B B
Vascularization of fetal neocortical grafts implanted in brain infarcts in spontaneously hypertensive rats.
Neuroscience 1992;51(3):673-82.
-
1992: Widner H; Tetrud J; Rehncrona S; Snow B; Brundin P; Gustavii B; Björklund A; Lindvall O; Langston J W
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
The New England journal of medicine 1992;327(22):1556-63.
-
1992: Wictorin K; Brundin P; Sauer H; Lindvall O; Björklund A
Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats.
The Journal of comparative neurology 1992;323(4):475-94.
-
1992: Grabowski M; Brundin P; Johansson B B
Fetal neocortical grafts implanted in adult hypertensive rats with cortical infarcts following a middle cerebral artery occlusion: ingrowth of afferent fibers from the host brain.
Experimental neurology 1992;116(2):105-21.
-
1992: Sawle G V; Bloomfield P M; Björklund A; Brooks D J; Brundin P; Leenders K L; Lindvall O; Marsden C D; Rehncrona S; Widner H
Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.
Annals of neurology 1992;31(2):166-73.
-
1992: Lindvall O; Widner H; Rehncrona S; Brundin P; Odin P; Gustavii B; Frackowiak R; Leenders K L; Sawle G; Rothwell J C
Transplantation of fetal dopamine neurons in Parkinson's disease: one-year clinical and neurophysiological observations in two patients with putaminal implants.
Annals of neurology 1992;31(2):155-65.
-
1991: Widner H; Brundin P; Rehncrona S; Gustavii B; Frackowiak R; Leenders K L; Sawle G; Rothwell J C; Marsden C D; Björklund A
Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease.
Transplantation proceedings 1991;23(1 Pt 1):793-5.
-
1991: Bengzon J; Brundin P; Kalén P; Kokaia M; Lindvall O
Host regulation of noradrenaline release from grafts of seizure-suppressant locus coeruleus neurons.
Experimental neurology 1991;111(1):49-54.
-
1991: Horellou P; Lundberg C; Le Bourdellès B; Wictorin K; Brundin P; Kalén P; Björklund A; Mallet J
Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease.
Journal de physiologie 1991;85(3):158-70.
-
1990: Murata Y; Chiba T; Brundin P; Björklund A; Lindvall O
Formation of synaptic graft-host connections by noradrenergic locus coeruleus neurons transplanted into the adult rat hippocampus.
Experimental neurology 1990;110(3):258-67.
-
1990: Brundin P; Odin P; Widner H
[Promising new results with transplantation of nerve cells to the brain in Parkinson disease]
Läkartidningen 1990;87(45):3761-3.
-
1990: Horellou P; Brundin P; Kalén P; Mallet J; Björklund A
In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum.
Neuron 1990;5(4):393-402.
-
1990: Wictorin K; Brundin P; Gustavii B; Lindvall O; Björklund A
Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts.
Nature 1990;347(6293):556-8.
-
1990: Nilsson O G; Brundin P; Björklund A
Amelioration of spatial memory impairment by intrahippocampal grafts of mixed septal and raphe tissue in rats with combined cholinergic and serotonergic denervation of the forebrain.
Brain research 1990;515(1-2):193-206.
-
1990: Lindvall O; Brundin P; Widner H; Rehncrona S; Gustavii B; Frackowiak R; Leenders K L; Sawle G; Rothwell J C; Marsden C D
Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease.
Science (New York, N.Y.) 1990;247(4942):574-7.
-
1990: Clarke D J; Nilsson O G; Brundin P; Björklund A
Synaptic connections formed by grafts of different types of cholinergic neurons in the host hippocampus.
Experimental neurology 1990;107(1):11-22.
-
1990: Lindvall O; Rehncrona S; Brundin P; Gustavii B; Astedt B; Widner H; Lindholm T; Björklund A; Leenders K L; Rothwell J C
Neural transplantation in Parkinson's disease: the Swedish experience.
Progress in brain research 1990;82():729-34.
-
1990: Brundin P; Björklund A; Lindvall O
Practical aspects of the use of human fetal brain tissue for intracerebral grafting.
Progress in brain research 1990;82():707-14.
-
1990: Bengzon J; Kokaia M; Brundin P; Lindvall O
Seizure suppression in kindling epilepsy by intrahippocampal locus coeruleus grafts: evidence for an alpha-2-adrenoreceptor mediated mechanism.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;81(2):433-7.
-
1990: Triarhou L C; Brundin P; Doucet G; Norton J; Björklund A; Ghetti B
Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;79(1):3-17.
-
1990: Lindvall O; Bengzon J; Brundin P; Kalén P; Kokaia M
Locus coeruleus grafts in hippocampal kindling epilepsy: noradrenaline release, receptor specificity and influence on seizure development.
Progress in brain research 1990;82():339-46.
-
1990: Wictorin K; Clarke D J; Bolam J P; Brundin P; Gustavii B; Lindvall O; Björklund A
Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing.
Progress in brain research 1990;82():391-9.
-
1989: Barry D I; Wanscher B; Kragh J; Bolwig T G; Kokaia M; Brundin P; Björklund A; Lindvall O
Grafts of fetal locus coeruleus neurons in rat amygdala-piriform cortex suppress seizure development in hippocampal kindling.
Experimental neurology 1989;106(2):125-32.
-
1989: Doucet G; Murata Y; Brundin P; Bosler O; Mons N; Geffard M; Ouimet C C; Björklund A
Host afferents into intrastriatal transplants of fetal ventral mesencephalon.
Experimental neurology 1989;106(1):1-19.
-
1989: Daszuta A; Kalén P; Strecker R E; Brundin P; Björklund A
Serotonin neurons grafted to the adult rat hippocampus. II. 5-HT release as studied by intracerebral microdialysis.
Brain research 1989;498(2):323-32.
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1989: Lindvall O; Rehncrona S; Brundin P; Gustavii B; Astedt B; Widner H; Lindholm T; Björklund A; Leenders K L; Rothwell J C
Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up.
Archives of neurology 1989;46(6):615-31.
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1989: Widner H; Brundin P; Björklund A; Möller E
Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;76(1):187-97.
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1989: Doucet G; Brundin P; Seth S; Murata Y; Strecker R E; Triarhou L C; Ghetti B; Björklund A
Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;77(3):552-68.
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1989: Forni C; Brundin P; Strecker R E; el Ganouni S; Björklund A; Nieoullon A
Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;76(1):75-87.
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1989: Brundin P; Widner H; Nilsson O G; Strecker R E; Björklund A
Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;75(1):195-207.
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1988: Lindvall O; Rehncrona S; Gustavii B; Brundin P; Astedt B; Widner H; Lindholm T; Björklund A; Leenders K L; Rothwell J C
Fetal dopamine-rich mesencephalic grafts in Parkinson's disease.
Lancet 1988;2(8626-8627):1483-4.
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1988: Widner H; Brundin P
Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis.
Brain research 1988;472(3):287-324.
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1988: Daszuta A; Strecker R E; Brundin P; Björklund A
Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry.
Brain research 1988;458(1):1-19.
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1988: Nilsson O G; Brundin P; Widner H; Strecker R E; Björklund A
Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern.
Brain research 1988;456(1):193-8.
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1988: Grabowski M; Nordborg C; Brundin P; Johansson B B
Middle cerebral artery occlusion in the hypertensive and normotensive rat: a study of histopathology and behaviour.
Journal of hypertension 1988;6(5):405-11.
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1988: Brundin P; Barbin G; Strecker R E; Isacson O; Prochiantz A; Björklund A
Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro.
Brain research 1988;467(2):233-43.
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1988: Nilsson O G; Clarke D J; Brundin P; Björklund A
Comparison of growth and reinnervation properties of cholinergic neurons from different brain regions grafted to the hippocampus.
The Journal of comparative neurology 1988;268(2):204-22.
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1988: Brundin P; Strecker R E; Widner H; Clarke D J; Nilsson O G; Astedt B; Lindvall O; Björklund A
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;70(1):192-208.
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1988: Gage F H; Brundin P; Strecker R; Dunnett S B; Isacson O; Bjorklund A
Intracerebral neuronal grafting in experimental animal models of age-related motor dysfunction.
Annals of the New York Academy of Sciences 1988;515():383-94.
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1988: Björklund A; Brundin P; Isacson O
Neuronal replacement by intracerebral neural implants in animal models of neurodegenerative disease.
Advances in neurology 1988;47():455-92.
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1988: Widner H; Brundin P; Björklund A; Möller E
Immunological aspects of neural grafting in the mammalian central nervous system.
Progress in brain research 1988;78():303-7.
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1988: Clarke D J; Brundin P; Strecker R E; Nilsson O G; Björklund A; Lindvall O
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;73(1):115-26.
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1988: Lindvall O; Barry D I; Kikvadze I; Brundin P; Bolwig T G; Björklund A
Intracerebral grafting of fetal noradrenergic locus coeruleus neurons: evidence for seizure suppression in the kindling model of epilepsy.
Progress in brain research 1988;78():79-86.
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1988: Brundin P; Strecker R E; Clarke D J; Widner H; Nilsson O G; Astedt B; Lindvall O; Björklund A
Can human fetal dopamine neuron grafts provide a therapy for Parkinson's disease?
Progress in brain research 1988;78():441-8.
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1988: Brundin P; Strecker R E; Gage F H; Lindvall O; Björklund A
Intracerebral transplantation of dopamine neurons: understanding the functional role of the mesolimbocortical dopamine system and developing a therapy for Parkinson's disease.
Annals of the New York Academy of Sciences 1988;537():148-60.
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1987: Barry D I; Kikvadze I; Brundin P; Bolwig T G; Björklund A; Lindvall O
Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8712-5.
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1987: Isacson O; Dawbarn D; Brundin P; Gage F H; Emson P C; Björklund A
Neural grafting in a rat model of Huntington's disease: striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography.
Neuroscience 1987;22(2):481-97.
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1987: Strecker R E; Sharp T; Brundin P; Zetterström T; Ungerstedt U; Björklund A
Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis.
Neuroscience 1987;22(1):169-78.
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1987: Brundin P; Björklund A
Survival, growth and function of dopaminergic neurons grafted to the brain.
Progress in brain research 1987;71():293-308.
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1987: Isacson O; Pritzel M; Dawbarn D; Brundin P; Kelly P A; Wiklund L; Emson P C; Gage F H; Dunnett S B; Björklund A
Striatal neural transplants in the ibotenic acid-lesioned rat neostriatum. Cellular and functional aspects.
Annals of the New York Academy of Sciences 1987;495():537-55.
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1987: Brundin P; Strecker R E; Lindvall O; Isacson O; Nilsson O G; Barbin G; Prochiantz A; Forni C; Nieoullon A; Widner H
Intracerebral grafting of dopamine neurons. Experimental basis for clinical trials in patients with Parkinson's disease.
Annals of the New York Academy of Sciences 1987;495():473-96.
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1987: Brundin P; Strecker R E; Londos E; Björklund A
Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1987;69(1):183-94.
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1986: Brundin P; Isacson O; Gage F H; Prochiantz A; Björklund A
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting.
Brain research 1986;366(1-2):346-9.
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1986: Brundin P; Isacson O; Gage F H; Björklund A
Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells.
Brain research 1986;389(1-2):77-84.
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1986: Zetterström T; Brundin P; Gage F H; Sharp T; Isacson O; Dunnett S B; Ungerstedt U; Björklund A
In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis.
Brain research 1986;362(2):344-9.
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1986: Brundin P; Nilsson O G; Strecker R E; Lindvall O; Astedt B; Björklund A
Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1986;65(1):235-40.
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1986: Pritzel M; Isacson O; Brundin P; Wiklund L; Björklund A
Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1986;65(1):112-26.
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1985: Isacson O; Brundin P; Gage F H; Björklund A
Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting.
Neuroscience 1985;16(4):799-817.
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1985: Brundin P; Barbin G; Isacson O; Mallat M; Chamak B; Prochiantz A; Gage F H; Björklund A
Survival of intracerebrally grafted rat dopamine neurons previously cultured in vitro.
Neuroscience letters 1985;61(1-2):79-84.
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1985: Gage F H; Brundin P; Isacson O; Björklund A
Rat fetal brain tissue grafts survive and innervate host brain following five day pregraft tissue storage.
Neuroscience letters 1985;60(2):133-7.
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1985: Brundin P; Isacson O; Björklund A
Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival.
Brain research 1985;331(2):251-9.
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1985: Brundin P; Nilsson O G; Gage F H; Björklund A
Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1985;60(1):204-8.
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1985: Emson P C; Dawbarn D; Rossor M N; Rehfeld J F; Brundin P; Isacson O; Björklund A
Cholecystokinin content in the basal ganglia in Huntington's disease. The expression of cholecystokinin immunoreactivity in striatal grafts to ibotenic acid-lesioned rat striatum.
Annals of the New York Academy of Sciences 1985;448():488-94.
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1984: Isacson O; Brundin P; Kelly P A; Gage F H; Björklund A
Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum.
Nature 1984;311(5985):458-60.
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1983: Gage F H; Dunnett S B; Brundin P; Isacson O; Björklund A
Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application.
Developmental neuroscience 1983;6(3):137-51.
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