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Puran Bora

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Valeriy V Lyzogubov; Ruslana G Tytarenko; Nalini S Bora; Puran S Bora
Inhibitory role of adiponectin peptide I on rat choroidal neovascularization.
Stephen J Davis; Valeriy V Lyzogubov; Ammar N Safar; Ruslana Tytarenko; Nalini S Bora; Puran S Bora
The effect of nicotine on anti-vascular endothelial growth factor therapy in a mouse model of neovascular age-related macular degeneration.
Purushottam Jha; Ruslana Tytarenko; Himanshu Banda; Puran S Bora; Nalini S Bora
Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma.

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2012: Valeriy V Lyzogubov; Ruslana G Tytarenko; Nalini S Bora; Puran S Bora
Inhibitory role of adiponectin peptide I on rat choroidal neovascularization.
Biochimica et biophysica acta 2012;1823(8):1264-72.
2012: Stephen J Davis; Valeriy V Lyzogubov; Ammar N Safar; Ruslana Tytarenko; Nalini S Bora; Puran S Bora
The effect of nicotine on anti-vascular endothelial growth factor therapy in a mouse model of neovascular age-related macular degeneration.
Retina (Philadelphia, Pa.) 2012;32(6):1171-80.
2011: Purushottam Jha; Ruslana Tytarenko; Himanshu Banda; Puran S Bora; Nalini S Bora
Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma.
Molecular immunology 2011;48(15-16):2151-8.
2011: Sami Uwaydat; Michael Wiggins; Puran S Bora; Harry Brown; Purushottam Jha; Ruslana Tytarenko; Nalini S Bora
The use of topical honey in the treatment of corneal abrasions and endotoxin-induced keratitis in an animal model.
Current eye research 2011;36(9):787-96.
2011: Juan Liu; Purushottam Jha; Valeriy V Lyzogubov; Ruslana G Tytarenko; Nalini S Bora; Puran S Bora
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
The Journal of biological chemistry 2011;286(23):20991-1001.
2011: Valeriy V Lyzogubov; Ruslana Tytarenko; Juan Liu; Nalini S Bora; Puran S Bora
Polyethylene glycol (PEG)-induced mouse model of choroidal neovascularization.
The Journal of biological chemistry 2011;286(18):16229-37.
2011: Balasubramanian Manickam; Purushottam Jha; Bharati Matta; Juan Liu; Puran S Bora; Nalini S Bora
Inhibition of complement alternative pathway suppresses experimental autoimmune anterior uveitis by modulating T cell responses.
The Journal of biological chemistry 2011;286(10):8472-80.
2010: Balasubramanian Manickam; Purushottam Jha; Natalie J Hepburn; B Paul Morgan; Claire L Harris; Puran S Bora; Nalini S Bora
Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU).
Molecular immunology 2010;48(1-3):231-9.
2010: Nalini S Bora; Purushottam Jha; Valeriy V Lyzogubov; Sankaranarayanan Kaliappan; Juan Liu; Ruslana Tytarenko; Deborah A Fraser; B Paul Morgan; Puran S Bora
Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice.
The Journal of biological chemistry 2010;285(44):33826-33.
2010: Bharati Matta; Purushottam Jha; Puran S Bora; Nalini S Bora
Antigen-specific tolerance inhibits autoimmune uveitis in pre-sensitized animals by deletion and CD4+CD25+ T-regulatory cells.
Immunology and cell biology 2010;88(2):187-96.
2009: Purushottam Jha; Balasubramanian Manickam; Bharati Matta; Puran S Bora; Nalini S Bora
Proteolytic cleavage of type I collagen generates an autoantigen in autoimmune uveitis.
The Journal of biological chemistry 2009;284(45):31401-11.
2009: Valeriy V Lyzogubov; Ruslana Tytarenko; Sushma Thotakura; Tito Viswanathan; Nalini S Bora; Puran S Bora
Inhibition of new vessel growth in mouse model of laser-induced choroidal neovascularization by adiponectin peptide II.
Cell biology international 2009;33(7):765-71.
2008: Bharati Matta; Purushottam Jha; Puran S Bora; Nalini S Bora
Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ T-regulatory cells.
The American journal of pathology 2008;173(5):1440-54.
2008: Sankaranarayanan Kaliappan; Purushottam Jha; Valeriy V Lyzogubov; Ruslana G Tytarenko; Nalini S Bora; Puran S Bora
Alcohol and nicotine consumption exacerbates choroidal neovascularization by modulating the regulation of complement system.
FEBS letters 2008;582(23-24):3451-8.
2008: Nalini S Bora; Purushottam Jha; Puran S Bora
The role of complement in ocular pathology.
Seminars in immunopathology 2008;30(2):85-95.
2008: Jason Y Chang; Puran S Bora; Nalini S Bora
Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARgamma Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J(2).
PPAR research 2008;2008():720163.
2007: Purushottam Jha; Bharati Matta; Valeriy V Lyzogubov; Ruslana Tytarenko; Puran S Bora; Nalini S Bora
Crucial role of apoptosis in the resolution of experimental autoimmune anterior uveitis.
Investigative ophthalmology & visual science 2007;48(11):5091-100.
2007: Purushottam Jha; Puran S Bora; Nalini S Bora
The role of complement system in ocular diseases including uveitis and macular degeneration.
Molecular immunology 2007;44(16):3901-8.
2007: Puran S Bora; Sankaranarayanan Kaliappan; Valeriy V Lyzogubov; Ruslana Tytarenko; Sushma Thotakura; Tito Viswanathan; Nalini S Bora
Expression of adiponectin in choroidal tissue and inhibition of laser induced choroidal neovascularization by adiponectin.
FEBS letters 2007;581(10):1977-82.
2007: Nalini S Bora; Sankaranarayanan Kaliappan; Purushottam Jha; Qin Xu; Baalasubramanian Sivasankar; Claire L Harris; B Paul Morgan; Puran S Bora
CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1783-90.
2007: JEONG-HYEON SOHN; Puran S Bora; Purushottam Jha; Tongalp H Tezel; Henry J Kaplan; Nalini S Bora
Complement, innate immunity and ocular disease.
Chemical immunology and allergy 2007;92():105-14.
2006: Nalini S Bora; Sankaranarayanan Kaliappan; Purushottam Jha; Qin Xu; JEONG-HYEON SOHN; Dhara B Dhaulakhandi; Henry J Kaplan; Puran S Bora
Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1872-8.
2006: Purushottam Jha; JEONG-HYEON SOHN; Qin Xu; Yali Wang; Henry J Kaplan; Puran S Bora; Nalini S Bora
Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU).
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7221-31.
2006: Puran S Bora; Sankaranarayanan Kaliappan; Qin Xu; Shalesh Kumar; Yali Wang; Henry J Kaplan; Nalini S Bora
Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization.
The FEBS journal 2006;273(7):1403-14.
2006: Purushottam Jha; JEONG-HYEON SOHN; Qin Xu; Hiroki Nishihori; Yali Wang; Saori Nishihori; Balasubramanian Manickam; Henry J Kaplan; Puran S Bora; Nalini S Bora
The complement system plays a critical role in the development of experimental autoimmune anterior uveitis.
Investigative ophthalmology & visual science 2006;47(3):1030-8.
2006: Purushottam Jha; Puran S Bora; JEONG-HYEON SOHN; Henry J Kaplan; Nalini S Bora
Complement system and the eye.
Advances in experimental medicine and biology 2006;586():53-62.
2005: Nalini S Bora; JEONG-HYEON SOHN; Puran S Bora; Henry J Kaplan; Prasad Kulkarni
Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU).
Ocular immunology and inflammation 2005;13(2-3):183-9.
2005: Puran S Bora; JEONG-HYEON SOHN; Jose M C Cruz; Purushottam Jha; Hiroki Nishihori; Yali Wang; Sankaranarayanan Kaliappan; Henry J Kaplan; Nalini S Bora
Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):491-7.
2004: Nalini S Bora; JEONG-HYEON SOHN; Shin-Goo Kang; Jose M C Cruz; Hiroki Nishihori; Hye-Jung Suk; Yali Wang; Henry J Kaplan; Puran S Bora
Type I collagen is the autoantigen in experimental autoimmune anterior uveitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7086-94.
2003: Puran S Bora; Bandula L Guruge; Nalini S Bora
Molecular characterization of human eye and heart fatty acid ethyl ester synthase/carboxylesterase by site-directed mutagenesis.
Biochemical and biophysical research communications 2003;312(4):1094-8.
2003: Jianjun Li; Weimin Hu; Joseph J Baldassare; Puran S Bora; Shuang Chen; John E Poulos; Rosemary O'Neill; Robert S Britton; Bruce R Bacon
The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells.
Life sciences 2003;73(9):1083-96.
2003: Puran S Bora; Zhiwei Hu; Tongalp H Tezel; JEONG-HYEON SOHN; Shin Goo Kang; Jose M C Cruz; Nalini S Bora; Alan Garen; Henry J Kaplan
Immunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2679-84.
2003: JEONG-HYEON SOHN; Puran S Bora; Hye-Jung Suk; Hector Molina; Henry J Kaplan; Nalini S Bora
Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells.
Nature medicine 2003;9(2):206-12.
2000: JEONG-HYEON SOHN; Henry J Kaplan; Hye-Jung Suk; Puran S Bora; Nalini S Bora
Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59.
Investigative ophthalmology & visual science 2000;41(13):4195-202.
2000: JEONG-HYEON SOHN; Henry J Kaplan; Hye-Jung Suk; Puran S Bora; Nalini S Bora
Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins.
Investigative ophthalmology & visual science 2000;41(11):3492-502.
1998: Puran S Bora; Donald D Miller; BR Chaitman
Mutagenesis and characterization of specific residues in fatty acid ethyl ester synthase: a gene for alcohol-induced cardiomyopathy.
Molecular and cellular biochemistry 1998;180(1-2):111-5.
1997: Puran S Bora; Bandula L Guruge; Donald D Miller; BR Chaitman; W Fortson
Human fatty acid ethyl ester synthase-III gene: genomic organization, nucleotide sequencing and chromosomal localization.
Molecular and cellular biochemistry 1997;173(1-2):145-51.
1997: R Merritt; Bandula L Guruge; Donald D Miller; B R Chaitman; Puran S Bora
Moderate alcohol feeding attenuates postinjury vascular cell proliferation in rabbit angioplasty model.
Journal of cardiovascular pharmacology 1997;30(1):19-25.
1997: Puran S Bora; Bandula L Guruge; Donald D Miller; BR Chaitman; M S Ruyle
Purification and characterization of human heart fatty acid ethyl ester synthase/carboxylesterase.
Journal of molecular and cellular cardiology 1997;29(1):425.
1996: Puran S Bora; Bandula L Guruge; Donald D Miller; B R Chaitman; M S Ruyle
Purification and characterization of human heart fatty acid ethyl ester synthase/carboxylesterase.
Journal of molecular and cellular cardiology 1996;28(9):2027-32.
1996: Nalini S Bora; Puran S Bora; M T Tandhasetti; T P Cirrito; Henry J Kaplan
Molecular cloning, sequencing, and expression of the 36 kDa protein present in pars planitis. Sequence homology with yeast nucleopore complex protein.
Investigative ophthalmology & visual science 1996;37(9):1877-83.
1996: Nalini S Bora; Puran S Bora; Henry J Kaplan
Identification, quantitation, and purification of a 36 kDa circulating protein associated with active pars planitis.
Investigative ophthalmology & visual science 1996;37(9):1870-6.
1996: Puran S Bora; M A Farrar; Donald D Miller; B R Chaitman; Bandula L Guruge
Myocardial cell damage by fatty acid ethyl esters.
Journal of cardiovascular pharmacology 1996;27(1):1-6.
1995: C M Smith; Puran S Bora; Nalini S Bora; C Jones; Daniela S Gerhard
Genetic and radiation-reduced somatic cell hybrid sublocalization of the human GSTP1 gene.
Cytogenetics and cell genetics 1995;71(3):235-9.
1994: Puran S Bora; C M Smith; E J Devor; C R Cloninger; Daniela S Gerhard
HinfI polymorphism detected by FAEES3 cDNA.
Human molecular genetics 1994;3(12):2267.
1994: A T Bello; Nalini S Bora; L G Lange; Puran S Bora
Cardioprotective effects of alcohol: mediation by human vascular alcohol dehydrogenase.
Biochemical and biophysical research communications 1994;203(3):1858-64.
1994: Puran S Bora; Nalini S Bora; X Wu; Henry J Kaplan; L G Lange
Molecular cloning, sequencing, and characterization of smooth muscle myosin alkali light chain from human eye cDNA: homology with myocardial fatty acid ethyl ester synthase-III cDNA.
Genomics 1994;19(1):186-8.
1993: Puran S Bora; L G Lange
Molecular mechanism of ethanol metabolism by human brain to fatty acid ethyl esters.
Alcoholism, clinical and experimental research 1993;17(1):28-30.
1992: Puran S Bora; X Wu; C A Spilburg; L G Lange
Purification and characterization of fatty acid ethyl ester synthase-II from human myocardium.
The Journal of biological chemistry 1992;267(19):13217-21.
1992: Keith E Isenberg; Puran S Bora; X Zhou; X Wu; Blake William Moore; L G Lange
Nonoxidative ethanol metabolism: expression of fatty acid ethyl ester synthase-III in cultured neural cells.
Biochemical and biophysical research communications 1992;185(3):938-43.
1992: Puran S Bora; X Wu; L G Lange
Site-specific mutagenesis of two histidine residues in fatty acid ethyl ester synthase-III.
Biochemical and biophysical research communications 1992;184(2):706-11.
1991: Puran S Bora; Nalini S Bora; X L Wu; L G Lange
Molecular cloning, sequencing, and expression of human myocardial fatty acid ethyl ester synthase-III cDNA.
The Journal of biological chemistry 1991;266(25):16774-7.
1991: Puran S Bora; L G Lange
Homogeneous synthase I from human myocardium is a glutathione S-transferase.
Annals of the New York Academy of Sciences 1991;625():827-9.
1989: Puran S Bora; C A Spilburg; L G Lange
Purification to homogeneity and characterization of major fatty acid ethyl ester synthase from human myocardium.
FEBS letters 1989;258(2):236-9.
1989: Puran S Bora; C A Spilburg; L G Lange
Identification of a satellite fatty acid ethyl ester synthase from human myocardium as a glutathione S-transferase.
The Journal of clinical investigation 1989;84(6):1942-6.
1989: Puran S Bora; C A Spilburg; L G Lange
Metabolism of ethanol and carcinogens by glutathione transferases.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4470-3.