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Job Harenberg

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Khaled Abduljalil; Christoph Gleiter; Job Harenberg; Victoria Kohl; Simone Lazar; Klaus Mörike; Michael Natanzon; Matthias Schwab; Benedict Steffens; Julia Stingl; Dorota Tomalik-Scharte; Weidong Wu; Gregor Zadoyan; Uwe Fuhr
Quantifying the effect of covariates on concentrations and effects of steady-state phenprocoumon using a population pharmacokinetic/pharmacodynamic model.
Job Harenberg; Shanshan Du; Christina Giese; Sandra Krämer; Astrid Schulze; Christel Weiss; Roland Krämer
Novel methods for assessing oral direct factor Xa and thrombin inhibitors: use of point-of-care testing and urine samples.
Job Harenberg; Christel Weiss
Clinical trials with new oral anticoagulants. Additive value of indirect comparisons also named network meta-analyses.

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2013: Khaled Abduljalil; Christoph Gleiter; Job Harenberg; Victoria Kohl; Simone Lazar; Klaus Mörike; Michael Natanzon; Matthias Schwab; Benedict Steffens; Julia Stingl; Dorota Tomalik-Scharte; Weidong Wu; Gregor Zadoyan; Uwe Fuhr
Quantifying the effect of covariates on concentrations and effects of steady-state phenprocoumon using a population pharmacokinetic/pharmacodynamic model.
Clinical pharmacokinetics 2013;52(5):359-71.
2013: Job Harenberg; Shanshan Du; Christina Giese; Sandra Krämer; Astrid Schulze; Christel Weiss; Roland Krämer
Novel methods for assessing oral direct factor Xa and thrombin inhibitors: use of point-of-care testing and urine samples.
Seminars in thrombosis and hemostasis 2013;39(1):66-71.
2013: Job Harenberg; Christel Weiss
Clinical trials with new oral anticoagulants. Additive value of indirect comparisons also named network meta-analyses.
Hämostaseologie 2013;33(1):62-70.
2013: Job Harenberg; Gregory Y H Lip
Differences between indirect comparison studies of the oral anticoagulants for stroke prevention in atrial fibrillation: where do we go next?
QJM : monthly journal of the Association of Physicians 2013;106(1):95-6.
2012: Job Harenberg; Victor J Marder; Svetlana Marx; Astrid Schulze; Martin Wehling; Ola E Dahl; Christel Weiss
Interpretation of endpoints in a network meta-analysis of new oral anticoagulants following total hip or total knee replacement surgery.
Thrombosis and haemostasis 2012;108(5):903-12.
2012: Job Harenberg; Svetlana Marx; Martin Wehling
Head-to-head or indirect comparisons of the novel oral anticoagulants in atrial fibrillation: what's next?
Thrombosis and haemostasis 2012;108(3):407-9.
2012: Eduard Condac; Charles T Esmon; Christina Giese; Gerardo Gutierrez-Sanchez; Job Harenberg; Christian Heiss; Darryl Johnson; Kelley W Moremen; Ron Orlando; Heather Strachan; Parastoo Azadi; Carl Bergmann; Benjamin Brainard; Lianchun Wang
The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity.
Glycobiology 2012;22(9):1183-92.
2012: Vito Ferro; Edward Hammond; Paul Handley; Job Harenberg; Ken D Johnstone; Tomislav Karoli; Cai Ping Li; Ligong Liu; Jessica Rowley; Laura Sarimaa; Norbert Wimmer; Kat Davis; Keith Dredge; Ian Bytheway
Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis.
Journal of medicinal chemistry 2012;55(8):3804-13.
2012: Job Harenberg; Roland Kraemer
Measurement of the new anticoagulants.
Thrombosis research 2012;129 Suppl 1():S106-13.
2012: Job Harenberg; Sandra Erdle; Svetlana Marx; Roland Krämer
Determination of rivaroxaban in human plasma samples.
Seminars in thrombosis and hemostasis 2012;38(2):178-84.
2012: Job Harenberg; Christina Giese; Svetlana Marx; Roland Krämer
Determination of dabigatran in human plasma samples.
Seminars in thrombosis and hemostasis 2012;38(1):16-22.
2012: Job Harenberg; Sandra Erdle; Svetlana Marx; Roland Krämer
Determination of the anticoagulant effects of new oral anticoagulants: an unmet need.
Expert review of hematology 2012;5(1):107-13.
2012: Oliver Dorsch; Stefan Fischer; Peter Bramlage; Detlef H Krieter; Horst-Dieter Lemke; Nima Melzer; Christian Sieder; Job Harenberg
A multi-center, prospective, open-label, 8-week study of certoparin for anticoagulation during maintenance hemodialysis - the membrane study.
BMC nephrology 2012;13():50.
2011: Job Harenberg
Differences of present recommendations and guidelines for generic low-molecular-weight heparins: is there room for harmonization.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2011;17(6):E158-64.
2011: Job Harenberg; Roland Krämer; Svetlana Marx; Christina Giese; Christel Weiss; Martin Wehling
Determination of rivaroxaban by different factor Xa specific chromogenic substrate assays: reduction of interassay variability.
Journal of thrombosis and thrombolysis 2011;32(3):267-71.
2011: Job Harenberg; Martin Wehling
Future of anticoagulant therapy.
Cardiovascular therapeutics 2011;29(5):291-300.
2011: Job Harenberg
Overview on guidelines and recommendations for generic low-molecular-weight heparins.
Thrombosis research 2011;127 Suppl 3():S100-4.
2010: Job Harenberg; R Bauersachs; Curt Diehm; Holger Lawall; Heinrich Burkhardt; H Gerlach; Harald Darius; H Völler; E Rabe; Martin Wehling
[Anticoagulation in the elderly].
Der Internist 2010;51(11):1446-55.
2010: Helga Szelke; Sarah Schübel; Job Harenberg; Roland Krämer
A fluorescent probe for the quantification of heparin in clinical samples with minimal matrix interference.
Chemical communications (Cambridge, England) 2010;46(10):1667-9.
2010: Ken D Johnstone; Tomislav Karoli; Ligong Liu; Keith Dredge; Elizabeth Copeman; Cai Ping Li; Kat Davis; Edward Hammond; Ian Bytheway; Edmund Kostewicz; Francis C K Chiu; David M Shackleford; Susan A Charman; William N Charman; Job Harenberg; Thomas J Gonda; Vito Ferro
Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.
Journal of medicinal chemistry 2010;53(4):1686-99.
2010: Helga Szelke; Sarah Schübel; Job Harenberg; Roland Krämer
Interaction of heparin with cationic molecular probes: probe charge is a major determinant of binding stoichiometry and affinity.
Bioorganic & medicinal chemistry letters 2010;20(4):1445-7.
2010: Job Harenberg
Idraparinux and idrabiotaparinux.
Expert review of clinical pharmacology 2010;3(1):9-16.
2009: Helga Szelke; Job Harenberg; Roland Krämer
Detection and neutralisation of heparin by a fluorescent ruthenium compound.
Thrombosis and haemostasis 2009;102(5):859-64.
2009: Job Harenberg
Development of idraparinux and idrabiotaparinux for anticoagulant therapy.
Thrombosis and haemostasis 2009;102(5):811-5.
2009: Job Harenberg; Benito Casu
Heparin and its derivatives - present and future.
Thrombosis and haemostasis 2009;102(5):801-3.
2009: Job Harenberg
New anticoagulants in atrial fibrillation.
Seminars in thrombosis and hemostasis 2009;35(6):574-85.
2009: Job Harenberg; A Kakkar; D Bergqvist; T Barrowcliffe; B Casu; J Fareed; P Mismetti; Frederick A Ofosu; W Raake; M Samama; S Schulman
Recommendations on biosimilar low-molecular-weight heparins.
Journal of thrombosis and haemostasis : JTH 2009;7(7):1222-5.
2009: Job Harenberg
LMWH - new mechanisms of action.
Thrombosis research 2009;123 Suppl 3():S1-4.
2008: Job Harenberg
Development of new anticoagulants: present and future.
Seminars in thrombosis and hemostasis 2008;34(8):779-93.
2008: Ulrich Tebbe; Ralph Oeckinghaus; Karl-Friedrich Appel; Hubertus Heuer; Hendrik Haake; Egbert Eggers; Karlheinz Seidel; Jan Adams; Job Harenberg
AFFECT: a prospective, open-label, multicenter trial to evaluate the feasibility and safety of a short-term treatment with subcutaneous certoparin in patients with persistent non-valvular atrial fibrillation.
Clinical research in cardiology : official journal of the German Cardiac Society 2008;97(6):389-96.
2008: Job Harenberg; Ingrid Jörg; Yvonne Vukojevic; Gerd Mikus; Christel Weiss
Anticoagulant effects of idraparinux after termination of therapy for prevention of recurrent venous thromboembolism: observations from the van Gogh trials.
European journal of clinical pharmacology 2008;64(6):555-63.
2008: Job Harenberg; Martin Wehling
Current and future prospects for anticoagulant therapy: inhibitors of factor Xa and factor IIa.
Seminars in thrombosis and hemostasis 2008;34(1):39-57.
2007: Rupert Bauersachs; Joachim Dudenhausen; Andree Faridi; Thorsten Fischer; Samson Fung; Ulrich Geisen; Job Harenberg; Eberhard Herchenhan; Franz Keller; Bettina Kemkes-Matthes; Helmut Schinzel; Michael Spannagl; Christian J Thaler
Risk stratification and heparin prophylaxis to prevent venous thromboembolism in pregnant women.
Thrombosis and haemostasis 2007;98(6):1237-45.
2007: Thomas Höchtl; Linda Pachinger; Gerhard Unger; Alexander Geppert; Johann Wojta; Job Harenberg; Kurt Huber
Antiplatelet drug induced isolated profound thrombocytopenia in interventional cardiology: a review based on individual case reports.
Journal of thrombosis and thrombolysis 2007;24(1):59-64.
2007: Jürgen Koscielny; Holger Kiesewetter; Ingrid Jörg; Job Harenberg
Ximelagatran for treatment and prophylaxis of recurrent events in deep vein thrombosis.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2007;13(3):299-307.
2007: Job Harenberg; Christina Giese; Antje Hagedorn; Inge Traeger; Tivadar Fenyvesi
Determination of antithrombin-dependent factor Xa inhibitors by prothrombin-induced clotting time.
Seminars in thrombosis and hemostasis 2007;33(5):503-7.
2007: Job Harenberg
Treatment of a woman with lupus and thromboembolism and cutaneous intolerance to heparins using fondaparinux during pregnancy.
Thrombosis research 2007;119(3):385-8.
2006: Job Harenberg; Ingrid Jörg; Christel Weiss
Observations of alanine aminotransferase and aspartate aminotransferase in THRIVE studies treated orally with ximelagatran.
International journal of toxicology 2006;25(3):165-9.
2006: Job Harenberg; Ingrid Jörg; Christel Weiss
Incidence of recurrent venous thromboembolism of patients after termination of treatment with ximelagatran.
European journal of clinical pharmacology 2006;62(3):173-7.
2006: Hans-Christoph Diener; E Bernd Ringelstein; Rüdiger von Kummer; Helmut Landgraf; Klaus Koppenhagen; Job Harenberg; Ivan Rektor; Attila Csányi; Dietmar Schneider; Jürgen Klingelhöfer; Joachim Brom; Gottfried Weidinger
Prophylaxis of thrombotic and embolic events in acute ischemic stroke with the low-molecular-weight heparin certoparin: results of the PROTECT Trial.
Stroke; a journal of cerebral circulation 2006;37(1):139-44.
2005: K M Bauer; Job Harenberg; Ingrid Jörg; P Diezler; Konrad Reinshagen; Heinrich Burkhardt; Rainer Gladisch
[Dysphagia after taking an acetaminophen-tablet during oral anticoagulation].
Der Internist 2005;46(12):1394-8.
2005: Martin Feuring; Job Harenberg; Angela Peiter; A Ganschow; Andreas Ruf; Ralf Losel; Martin Wehling; Armin Schultz
Impact of ABO blood groups on tirofiban mediated inhibition of platelet function.
Platelets 2005;16(7):430-4.
2005: Tivadar Fenyvesi; Job Harenberg; Christel Weiss; Ingrid Jörg
Comparison of two different ecarin clotting time methods.
Journal of thrombosis and thrombolysis 2005;20(1):51-6.
2005: Job Harenberg; Harenberg Job; Ingrid Jörg; Jörg Ingrid; Tivadar Fenyvesi; Fenyvesi Tivadar; Lukas Piazolo; Piazolo Lukas
Treatment of patients with a history of heparin-induced thrombocytopenia and anti-lepirudin antibodies with argatroban.
Journal of thrombosis and thrombolysis 2005;19(1):65-9.
2005: Ingrid Jörg; Job Harenberg; Tivadar Fenyvesi; Rainer Gladisch
[Atrial fibrillation and thromboprophylaxis in elderly patients].
Zeitschrift für Kardiologie 2005;94(2):87-94.
2005: Job Harenberg; Ingrid Jörg; C Bayerl; C Fiehn
Treatment of a woman with lupus pernio, thrombosis and cutaneous intolerance to heparins using lepirudin during pregnancy.
Lupus 2005;14(5):411-2.
2005: Bettina Kemkes-Matthes; Jeanine M Walenga; Job Harenberg; Jawed Fareed
Argatroban treatment for patients with intolerance to heparin and hirudin.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2005;11(1):99-103.
2004: Job Harenberg; Tivadar Fenyvesi
[Heparin, thrombin and Factor Xa inhibitors].
Hämostaseologie 2004;24(4):261-78.
2004: Tivadar Fenyvesi; Ingrid Jörg; Christel Weiss; Job Harenberg
Effects of vitamin K antagonist phenprocoumon on activated partial thromboplastin time measurement of direct thrombin inhibitors.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2004;15(7):605-11.
2004: Job Harenberg; Ingrid Jörg; Tivadar Fenyvesi
Treatment of heparin-induced thrombocytopenia with fondaparinux.
Haematologica 2004;89(8):1017-8.
2004: Ludwig Caspary; RM Bauersachs; S Brehme; Andreas Creutzig; Job Harenberg; U Hoffmann; Helmut Landgraf; Sebastian M Schellong
[Prevention and treatment of deep vein thrombosis with ximelagatran].
Deutsche medizinische Wochenschrift (1946) 2004;129(30):1635-40.
2004: Job Harenberg; Ingrid Jörg; S Koch; Tivadar Fenyvesi
[Lepirudin for therapeutic use in heparin-induced thrombocytopenia].
Hämostaseologie 2004;24(2):135-43.
2003: Job Harenberg; Hanno Riess; Harry R Büller; Joachim Brom; Gottfried Weidinger; Menno V Huisman
Comparison of six-month outcome of patients initially treated for acute deep vein thrombosis with a low molecular weight heparin Certoparin at a fixed, body-weight-independent dosage or unfractionated heparin.
Haematologica 2003;88(10):1157-62.
2003: Job Harenberg
[Treatment of thrombosis with low-molecular-weight heparin. Comparison of body weight-adjusted and fixed dosage].
Medizinische Klinik (Munich, Germany : 1983) 2003;98(9):493-8.
2003: Hanno Riess; Klaus Koppenhagen; Alexander R Tolle; Bettina Kemkes-Matthes; Michael Gräve; Frantisek Patek; Michael Drexler; Hans-Joachim G Siemens; Job Harenberg; Gottfried Weidinger; Joachim Brom; Sylvia Haas
Fixed-dose, body weight-independent subcutaneous low molecular weight heparin Certoparin compared with adjusted-dose intravenous unfractionated heparin in patients with proximal deep venous thrombosis.
Thrombosis and haemostasis 2003;90(2):252-9.
2003: Tivadar Fenyvesi; Ingrid Jörg; Christel Weiss; Job Harenberg
Effects of lepirudin, argatroban and melagatran and additional influence of phenprocoumon on ecarin clotting time.
Thrombosis research 2003;111(1-2):89-94.
2002: Job Harenberg; Jörg Ingrid; Fenyvesi Tivadar
Treatment of venous thromboembolism with the oral thrombin inhibitor, ximelagatran.
The Israel Medical Association journal : IMAJ 2002;4(11):1003-5.
2002: Tivadar Fenyvesi; Ingrid Joerg; Job Harenberg
Influence of lepirudin, argatroban, and melagatran on prothrombin time and additional effect of oral anticoagulation.
Clinical chemistry 2002;48(10):1791-4.
2002: Job Harenberg
Emerging concepts in thromboprophylaxis.
Pathophysiology of haemostasis and thrombosis 2002;32(5-6):398-400.
2002: Job Harenberg; Ingrid Jörg; Tivadar Fenyvesi
Heparin-induced thrombocytopenia: pathophysiology and new treatment options.
Pathophysiology of haemostasis and thrombosis 2002;32(5-6):289-94.
2002: Ingrid Jörg; Tivadar Fenyvesi; Job Harenberg
Anticoagulant-related skin reactions.
Expert opinion on drug safety 2002;1(3):287-94.
2002: K Rossol-Haseroth; C Ulrich Vogel; F Reinecke; Heinrich Burkhardt; Ch Heun-Letsch; B Wieth; Angela Peiter; U Heinrich; Ingrid Jörg; H Völler; B Kemkes-Matthes; T K Nordt; H C Diener; M Gehrlein; Rainer Gladisch; Martin Wehling; Job Harenberg
[Recommendations for prevention of thromboembolism in elderly internal medicine patients].
Der Internist 2002;43(9):1134-47.
2002: Job Harenberg
Fixed-dose versus adjusted-dose low molecular weight heparin for the initial treatment of patients with deep venous thrombosis.
Current opinion in pulmonary medicine 2002;8(5):383-8.
2002: Job Harenberg; Kirsten Merx; Ursula Hoffmann; Alexander R Tolle; Menno V Huisman
Association of changes in D-dimer and other coagulation markers with changes in Marder score after treatment of acute venous thrombosis.
Journal of thrombosis and thrombolysis 2002;14(1):73-8.
2002: Job Harenberg; Kawei Zokai; Lukas Piazolo; Tivadar Fenyvesi; Ingrid Jörg
Comparative antithrombotic potencies of direct thrombin inhibitors and low-molecular-weight heparins in an ex vivo human experimental thrombosis model.
Seminars in thrombosis and hemostasis 2002;28(4):379-82.
2002: Tivadar Fenyvesi; Ingrid Jörg; Job Harenberg
Monitoring of anticoagulant effects of direct thrombin inhibitors.
Seminars in thrombosis and hemostasis 2002;28(4):361-8.
2002: Job Harenberg; Benito Casu; marco Guerrini; Reinhard Malsch; Annamaria Naggi; Lukas Piazolo; Giangiacomo Torri
Low-molecular-weight heparin and dermatan sulfate end group-labeled with tyramine and fluorescein. Biochemical and biological characterization of the fluorescent-labeled heparin derivative.
Seminars in thrombosis and hemostasis 2002;28(4):343-54.
2002: Job Harenberg; Tivadar Fenyvesi; Ingrid Jörg
[Ximelagatran for treatment of venous thromboembolism].
Hämostaseologie 2002;22(3):25-9.
2002: Tivadar Fenyvesi; Ingrid Jörg; Job Harenberg
Effect of phenprocoumon on monitoring of lepirudin, argatroban, melagatran and unfractionated heparin with the PiCT method.
Pathophysiology of haemostasis and thrombosis 2002;32(4):174-9.
2002: Sandra Koch; Job Harenberg; Michael Odel; Heinrich Schmidt-Gayk; Stefan Walch; Uwe Budde
Development of a high-pressure liquid chromatography method for diagnosis of heparin-induced thrombocytopenia.
American journal of clinical pathology 2002;117(6):900-4.
2002: U Hoffmann; Job Harenberg; K Bauer; Guenter Huhle; Alexander R Tolle; Martin Feuring; M Christ
Bioequivalence of subcutaneous and intravenous body-weight-independent high-dose low-molecular-weight heparin Certoparin on anti-Xa, Heptest, and tissue factor pathway inhibitor activity in volunteers.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2002;13(4):289-96.
2002: S Koch; M Odel; Heinrich Schmidt-Gayk; Stefan Walch; U Budde; Job Harenberg
[Development of an HPLC method for the diagnosis of heparin-induced thrombocytopenia].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2002;37 Suppl 1():S12.
2002: Job Harenberg
[Management of HIT II patients with hirudin antibodies after primary therapy].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2002;37 Suppl 1():S8-11.
2001: K Zokai; Lukas Piazolo; Job Harenberg
Effect of thrombin inhibitors and a glycoprotein IIb/IIIa receptor antagonist in an ex vivo human experimental thrombosis model.
Seminars in thrombosis and hemostasis 2001;27(5):531-6.
2001: Job Harenberg; Menno V Huisman; Alexander R Tolle; Hans Klaus Breddin; Carl M Kirchmaier
Reduction in thrombus extension and clinical end points in patients after initial treatment for deep vein thrombosis with the fixed-dose body weight-independent low molecular weight heparin certoparin.
Seminars in thrombosis and hemostasis 2001;27(5):513-8.
2001: P Kaiser; Job Harenberg; Jeanine M Walenga; Guenter Huhle; Christina Giese; M Margaret Prechel; D Hoppensteadt; J Fareed
Effects of a heparin-binding protein on blood coagulation and platelet function.
Seminars in thrombosis and hemostasis 2001;27(5):495-502.
2001: Job Harenberg; L C Wang; U Hoffmann; Guenter Huhle; Martin Feuring
Laboratory diagnosis of heparin-induced thrombocytopenia type II after clearance of platelet factor 4/heparin complex.
The Journal of laboratory and clinical medicine 2001;137(6):408-13.
2001: Job Harenberg; L Wang; U Hoffmann; Guenter Huhle; Martin Feuring
Improved laboratory confirmation of heparin-induced thrombocytopenia type II. Time course of antibodies and combination of antigen and biologic assays.
American journal of clinical pathology 2001;115(3):432-8.
2001: Job Harenberg; Ursula Hoffmann; Guenter Huhle; M Winkler; Christiane Bayerl
Cutaneous reactions to anticoagulants. Recognition and management.
American journal of clinical dermatology 2001;2(2):69-75.
2000: Guenter Huhle; Ursula Hoffmann; I Hoffmann; Volker Liebe; Job Harenberg; DL Heene
A new therapeutic option by subcutaneous recombinant hirudin in patients with heparin-induced thrombocytopenia type II: a pilot study.
Thrombosis research 2000;99(4):325-34.
2000: XH Song; Guenter Huhle; LC Wang; Job Harenberg
Quantitative determination of PEG-hirudin in human plasma using a competitive enzyme-linked immunosorbent assay.
Thrombosis research 2000;99(2):195-202.
2000: Job Harenberg
Risk assessment of venous thromboembolism in medical patients.
Seminars in hematology 2000;37(3 Suppl 5):3-6.
2000: Guenter Huhle; U Hoffmann; I Hoffmann; Job Harenberg; DL Heene
[Prevention of thrombosis with subcutaneous recombinant hirudin in heparin-induced thrombocytopenia type II. A pilot study].
Deutsche medizinische Wochenschrift (1946) 2000;125(22):686-91.
2000: Job Harenberg; Guenter Huhle; LC Wang; Ursula Hoffmann; XH Song
Re-exposure to recombinant (r)-hirudin in antihirudin antibody-positive patients with a history of heparin-induced thrombocytopenia.
British journal of haematology 2000;109(2):360-3.
2000: Job Harenberg; S Koch; Christina Giese; L C Wang; Ursula Hoffmann; Guenter Huhle
Quantitation of serotonin from platelets using enzyme-immunoassay in the presence of serum from HIT-patients.
Thrombosis and haemostasis 2000;83(5):795-6.
2000: Job Harenberg; J A Schmidt; Klaus Koppenhagen; Alexander R Tolle; Menno V Huisman; H R Büller
Fixed-dose, body weight-independent subcutaneous LMW heparin versus adjusted dose unfractionated intravenous heparin in the initial treatment of proximal venous thrombosis. EASTERN Investigators.
Thrombosis and haemostasis 2000;83(5):652-6.
2000: Job Harenberg; Guenter Huhle; Christina Giese; LC Wang; Martin Feuring; XH Song; Ursula Hoffmann
Determination of serotonin release from platelets by enzyme immunoassay in the diagnosis of heparin-induced thrombocytopenia.
British journal of haematology 2000;109(1):182-6.
2000: Job Harenberg; Ursula Hoffmann; Guenter Huhle; XH Song; LC Wang
Treatment of an acute flush reaction caused by subcutaneous r-hirudin with pegylated hirudin.
British journal of haematology 2000;108(3):528-30.
2000: Guenter Huhle; M Geberth; Ursula Hoffmann; DL Heene; Job Harenberg
Management of heparin-associated thrombocytopenia in pregnancy with subcutaneous r-hirudin.
Gynecologic and obstetric investigation 2000;49(1):67-9.
1999: X Song; Guenter Huhle; L Wang; Ursula Hoffmann; Job Harenberg
Generation of anti-hirudin antibodies in heparin-induced thrombocytopenic patients treated with r-hirudin.
Circulation 1999;100(14):1528-32.
1999: Guenter Huhle; CB Abletshauser; N Mayer; Gottfried Weidinger; Job Harenberg; DL Heene
Reduction of platelet activity markers in type II hypercholesterolemic patients by a HMG-CoA-reductase inhibitor.
Thrombosis research 1999;95(5):229-34.
1999: Job Harenberg; G Huhle; U Hoffmann
[Antithrombotic therapy. Modern therapeutic approaches].
Der Internist 1999;40(8):885-93.
1999: Job Harenberg; Guenter Huhle; L Wang; Ursula Hoffmann; Christiane Bayerl; Mohammed Kerowgan
Association of heparin-induced skin lesions, intracutaneous tests, and heparin-induced IgG.
Allergy 1999;54(5):473-7.
1999: L C Wang; Guenter Huhle; Reinhard Malsch; V Hoffmann; X L Song; Job Harenberg
Determination of heparin-induced IgG antibody in heparin-induced thrombocytopenia type II.
European journal of clinical investigation 1999;29(3):232-7.
1999: W Kulinna; D Ney; T Wenzel; DL Heene; Job Harenberg
The effect of self-monitoring the INR on quality of anticoagulation and quality of life.
Seminars in thrombosis and hemostasis 1999;25(1):123-6.
1999: L Wang; Guenter Huhle; Reinhard Malsch; U Hoffmann; X Song; Job Harenberg
Determination of heparin-induced IgG antibody by fluorescence-linked immunofiltration assay (FLIFA).
Journal of immunological methods 1999;222(1-2):93-9.
1998: Job Harenberg; Lukas Piazolo; F Misselwitz
[Prevention of thromboembolism with low-molecular-weight heparin in ambulatory surgery and unoperated surgical and orthopedic patients].
Zentralblatt für Chirurgie 1998;123(11):1284-7.
1997: Job Harenberg; Guenter Huhle; Lukas Piazolo; Reinhard Malsch
[Low-molecular-weight heparins. The prevention and therapy of thromboembolic diseases].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1997;48(11):852-64.
1997: Job Harenberg; Guenter Huhle; Lukas Piazolo; L U Wang; DL Heene
Anticoagulation in patients with heparin-induced thrombocytopenia type II.
Seminars in thrombosis and hemostasis 1997;23(2):189-96.
1997: Job Harenberg; Guenter Huhle; Lukas Piazolo; Christina Giese; DL Heene
Long-term anticoagulation of outpatients with adverse events to oral anticoagulants using low-molecular-weight heparin.
Seminars in thrombosis and hemostasis 1997;23(2):167-72.
1997: Lukas Piazolo; Job Harenberg; Reinhard Malsch; F G Hüttner; DL Heene
Comparison of the pharmacodynamic and pharmacokinetic profiles of two low-molecular-mass heparins in rats.
Seminars in thrombosis and hemostasis 1997;23(2):109-17.
1997: Reinhard Malsch; marco Guerrini; C Berti; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Job Harenberg
Synthesis and biological effects of N-alkylamine-labeled low-molecular-mass dermatan sulfate.
Seminars in thrombosis and hemostasis 1997;23(2):99-107.
1997: Job Harenberg; U Schmitz-Huebner; K H Breddin; S Hass; Fritz Heinrich; C Heinrichs; J Kienast; P Roebruck; W Theiss; E Wenzel
Treatment of deep vein thrombosis with low-molecular-weight heparins: a consensus statement of the Gesellschaft für Thrombose-und Hämostaseforschung (GTH).
Seminars in thrombosis and hemostasis 1997;23(1):91-6.
1997: Job Harenberg; Gerd Stehle; M Blauth; K Huck; K Mall; DL Heene
Dosage, anticoagulant, and antithrombotic effects of heparin and low-molecular-weight heparin in the treatment of deep vein thrombosis.
Seminars in thrombosis and hemostasis 1997;23(1):83-90.
1997: Reinhard Malsch; A Timmermann; Job Harenberg
Capillary electrophoresis of r-hirudin and a polyethylene glycol derivative of r-hirudin (PEG-hirudin).
Seminars in thrombosis and hemostasis 1997;23(1):39-43.
1997: Gerd Stehle; Andreas Wunder; Hans-Peter Sinn; Hans-Hermann Schrenk; Job Harenberg; Reinhard Malsch; W Maier-Borst; DL Heene
Pharmacokinetic properties of LMW-heparin-tyramine fractions with high or low affinity to antithrombin III in the rat.
Seminars in thrombosis and hemostasis 1997;23(1):31-7.
1997: Reinhard Malsch; D Melui; Lukas Piazolo; Job Harenberg; DL Heene
Measurement of fluorescent-labeled LMM-heparin in biological fluids using protamine-linked microbeads.
Seminars in thrombosis and hemostasis 1997;23(1):23-30.
1997: Guenter Huhle; Job Harenberg; Reinhard Malsch; DL Heene
Monoclonal antibodies against heparin and heparinoids.
Seminars in thrombosis and hemostasis 1997;23(1):17-22.
1997: L Wang; Reinhard Malsch; Job Harenberg
Heparins, low-molecular-weight heparins, and other glycosaminoglycans analyzed by agarose gel electrophoresis and azure A-silver staining.
Seminars in thrombosis and hemostasis 1997;23(1):11-6.
1996: Reinhard Malsch; Job Harenberg; Lukas Piazolo; Guenter Huhle; DL Heene
Chromatographic and electrophoretic applications for the analysis of heparin and dermatan sulfate.
Journal of chromatography. B, Biomedical applications 1996;685(2):223-31.
1996: Reinhard Malsch; T Mrotzek; Guenter Huhle; Job Harenberg
Purification of the monoclonal heparin antibody H-1.18.
Journal of chromatography. A 1996;744(1-2):215-21.
1996: Job Harenberg; Reinhard Malsch; Lukas Piazolo; Guenter Huhle; DL Heene
Preferential binding of heparin to granulocytes of various species.
American journal of veterinary research 1996;57(7):1016-20.
1996: Job Harenberg; Reinhard Malsch; M Angelescu; C Lange; H C Michaelis; H Wolf; DL Heene
Anticoagulant effects and tissue factor pathway inhibitor after intrapulmonary low-molecular-weight heparin.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(4):477-83.
1996: Job Harenberg; T Reichel; Reinhard Malsch; J Hirsh; P Rustagi
Multicentric evaluation of heparinase on aPTT, thrombin clotting time and a new PT reagent based on recombinant human tissue factor.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(4):453-8.
1996: Job Harenberg; P Roebruck; DL Heene
Subcutaneous low-molecular-weight heparin versus standard heparin and the prevention of thromboembolism in medical inpatients. The Heparin Study in Internal Medicine Group.
Haemostasis 1996;26(3):127-39.
1996: Job Harenberg; Reinhard Malsch; Lukas Piazolo; Guenter Huhle; DL Heene
Analysis of heparin binding to human leukocytes using a fluorescein-5-isothiocyanate labeled heparin fragment.
Cytometry 1996;23(1):59-66.
1996: Job Harenberg; M Jeschek; M Acker; Reinhard Malsch; Guenter Huhle; DL Heene
Effects of low-molecular-weight dermatan sulfate on coagulation, fibrinolysis and tissue factor pathway inhibitor in healthy volunteers.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(1):49-56.
1995: Reinhard Malsch; Lukas Piazolo; Job Harenberg; DL Heene
N' alkylamine low molecular mass heparins (LMM-heparin-tyramine and LMM-heparin-tyramine-fitc) exhibit long lasting anticoagulant effects.
Thrombosis research 1995;80(3):235-46.
1995: Job Harenberg; G Löhr; Reinhard Malsch; marco Guerrini; Giangiacomo Torri; Benito Casu; DL Heene
Magnetic bead protamine-linked microtiter assay for detection of heparin using iodinated low-molecular-mass heparin-tyramine.
Thrombosis research 1995;79(2):207-16.
1995: Job Harenberg; Reinhard Malsch; DL Heene
Tissue factor pathway inhibitor: proposed heparin recognition region.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1995;6 Suppl 1():S50-6.
1995: Andreas Wunder; Gerd Stehle; Hans-Peter Sinn; Hans-Hermann Schrenk; B Neufeld; C E Dempfle; Hans Dresel; E Freidrich; Job Harenberg; W Maier-Borst
The injection of heparin prolongs the plasma clearance of oxidized low density lipoprotein in the rat.
Thrombosis research 1995;78(2):139-49.
1995: Job Harenberg; B Haaf; C E Dempfle; Gerd Stehle; DL Heene
Monitoring of heparins in haemodialysis using an anti-factor-Xa-specific whole-blood clotting assay.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1995;10(2):217-22.
1994: Reinhard Malsch; marco Guerrini; Giangiacomo Torri; G Löhr; Benito Casu; Job Harenberg
Synthesis of a N'-alkylamine anticoagulant active low-molecular-mass heparin for radioactive and fluorescent labeling.
Analytical biochemistry 1994;217(2):255-64.
1994: Guenter Huhle; Job Harenberg; Reinhard Malsch; DL Heene
Comparison of three heparin bovine serum albumin binding methods for production of antiheparin antibodies.
Seminars in thrombosis and hemostasis 1994;20(2):193-204.
1994: Reinhard Malsch; Job Harenberg; marco Guerrini; Giangiacomo Torri; Benito Casu; DL Heene
Semisynthesis and analysis of lipophilically modified unfractionated and low molecular mass heparins.
Seminars in thrombosis and hemostasis 1994;20(2):182-92.
1994: Reinhard Malsch; Job Harenberg
High-performance size exclusion chromatography and polyacrylamide gel electrophoresis for characterization of unfractionated and low molecular mass glycosaminoglycans.
Seminars in thrombosis and hemostasis 1994;20(2):135-43.
1994: Job Harenberg; Reinhard Malsch; Lukas Piazolo; DL Heene
Competitive binding of low molecular mass heparin-tyramine fluorescein-5-isothiocyanate and unlabeled glycosaminoglycans to leukocytes.
Seminars in thrombosis and hemostasis 1994;20(3):236-44.
1994: Lukas Piazolo; Job Harenberg; Reinhard Malsch; DL Heene
Binding of fluorescent-labeled low molecular mass heparin to latex microspheres and to rat and human leukocytes.
Seminars in thrombosis and hemostasis 1994;20(3):227-35.
1993: Job Harenberg; M Siegele; C E Dempfle; Gerd Stehle; DL Heene
Protamine neutralization of the release of tissue factor pathway inhibitor activity by heparins.
Thrombosis and haemostasis 1993;70(6):942-5.
1993: Gerd Stehle; Hans-Peter Sinn; E A Friedrich; Andreas Wunder; Hans-Hermann Schrenk; Job Harenberg; Peter Peschke; C E Dempfle; W Maier-Borst; DL Heene
Altered pharmacokinetic properties of a lipophilically derivatized low-molecular-weight heparin in rats.
The Journal of laboratory and clinical medicine 1993;122(6):728-38.
1993: Job Harenberg; D Schneider; Lothar Heilmann; H Wolf
Lack of anti-factor Xa activity in umbilical cord vein samples after subcutaneous administration of heparin or low molecular mass heparin in pregnant women.
Haemostasis 1993;23(6):314-20.
1993: Job Harenberg; B Haaf; M Schäfer; C E Dempfle; Gerd Stehle; DL Heene
Anti-factor Xa determination in blood: a new method for controlling heparin therapy.
Seminars in thrombosis and hemostasis 1993;19 Suppl 1():79-85.
1992: Gerd Stehle; E A Friedrich; Hans-Peter Sinn; Andreas Wunder; Job Harenberg; C E Dempfle; W Maier-Borst; DL Heene
Hepatic uptake of a modified low molecular weight heparin in rats.
The Journal of clinical investigation 1992;90(5):2110-6.
1992: Job Harenberg; P Roebruck; Gerd Stehle; W Habscheid; M Biegholdt; DL Heene
Heparin Study in Internal Medicine (HESIM): design and preliminary results.
Thrombosis research 1992;68(1):33-43.
1991: M Schmidt; Trevor Barrowcliffe; Elaine Gray; J Watton; Job Harenberg
Anti-Xa clotting activities in different hepatic-triglyceride lipase preparations from post-heparin plasma.
Thrombosis research 1991;63(5):503-8.
1990: Job Harenberg
Pharmacology of low molecular weight heparins.
Seminars in thrombosis and hemostasis 1990;16 Suppl():12-8.
1990: Job Harenberg; B Kallenbach; U Martin; C E Dempfle; R Zimmermann; Wolfgang Kübler; DL Heene
Randomized controlled study of heparin and low molecular weight heparin for prevention of deep-vein thrombosis in medical patients.
Thrombosis research 1990;59(3):639-50.
1990: Job Harenberg; K Huck; H Bratsch; Gerd Stehle; C E Dempfle; K Mall; M Blauth; K H Usadel; DL Heene
Therapeutic application of subcutaneous low-molecular-weight heparin in acute venous thrombosis.
Haemostasis 1990;20 Suppl 1():205-19.
1989: Job Harenberg; Gerd Stehle; J Augustin; R Zimmermann
Comparative human pharmacology of low molecular weight heparins.
Seminars in thrombosis and hemostasis 1989;15(4):414-23.
1989: Job Harenberg; C Giese; C E Dempfle; Gerd Stehle; DL Heene
Biological activity and safety of the subcutaneous administration of high doses of low molecular weight heparin for 8 days in human volunteers.
Thrombosis and haemostasis 1989;61(3):357-62.
1989: Job Harenberg; G Leber; C E Dempfle; DL Heene; R Zimmermann; Wolfgang Kübler
Long term anticoagulation with low molecular weight heparin in outpatients with side effects on oral anticoagulants.
Nouvelle revue française d'hématologie 1989;31(5):363-9.
1989: Job Harenberg; C Giese; A Knödler; R Zimmermann
Comparative study on a new one-stage clotting assay for heparin and its low molecular weight derivatives.
Haemostasis 1989;19(1):13-20.
1989: Job Harenberg; Gerd Stehle; C E Dempfle; E von Hodenberg; DL Heene
The pharmacological profile of the low molecular weight heparin 21-23 in man: anticoagulant, lipolytic and protamine reversible effects.
Folia haematologica (Leipzig, Germany : 1928) 1989;116(6):967-80.
1988: Job Harenberg; C Giese; C E Dempfle; Gerd Stehle; DL Heene
Monitoring of heparin and low molecular weight heparin with capillary and venous whole blood.
Thrombosis and haemostasis 1988;60(3):377-81.
1988: Job Harenberg; C Giese; R Zimmermann
Effect of dried garlic on blood coagulation, fibrinolysis, platelet aggregation and serum cholesterol levels in patients with hyperlipoproteinemia.
Atherosclerosis 1988;74(3):247-9.
1988: Job Harenberg; DL Heene
Pharmacology and special clinical applications of low-molecular-weight heparins.
American journal of hematology 1988;29(4):233-40.
1988: Job Harenberg
Relation of antifactor Xa activity of heparins and antithrombotic efficacy.
Haemostasis 1988;18 Suppl 3():16-9.
1988: Job Harenberg; G Leber; R Raedsch; R Zimmermann; F Schwarz; Wolfgang Kübler
Primary and secondary long-term prophylaxis of thromboembolism in outpatients with the low-molecular-weight heparin Kabi 2165.
Haemostasis 1988;18 Suppl 3():78-81.
1988: Job Harenberg; M Schuler; R Zimmermann; W Heptner
Significance of thrombin-receptors of thrombocytes for the interaction of heparins and low-molecular-weight heparin in human whole blood clotting.
Haemostasis 1988;18 Suppl 3():20-2.
1987: Job Harenberg; G Leber; J Augustin; R Raedsch; F Schwarz; A Stiehl; R Zimmermann
[Ambulatory long-term prevention of thromboembolism with low-molecular weight heparin].
Klinische Wochenschrift 1987;65(7):331-7.
1986: Job Harenberg; C Giese; A Knödler; R Zimmermann; G Schettler
[Neutralization of low molecular weight heparin Kabi 2165 by protamine chloride].
Klinische Wochenschrift 1986;64(22):1171-5.