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Juergen Koepke

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Yvonne Thielmann; Juergen Koepke; Hartmut Michel
The ESFRI Instruct Core Centre Frankfurt: automated high-throughput crystallization suited for membrane proteins and more.
Juergen Koepke; Elena Olkhova; Heike Angerer; Hannelore Müller; Guohong Peng; Hartmut Michel
High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: new insights into the active site and the proton transfer pathways.
Katharina L Dürr; Juergen Koepke; Petra Hellwig; Hannelore Müller; Heike Angerer; Guohong Peng; Elena Olkhova; Oliver-Matthias H Richter; Bernd Ludwig; Hartmut Michel
A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate.

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All Publications

2012: Yvonne Thielmann; Juergen Koepke; Hartmut Michel
The ESFRI Instruct Core Centre Frankfurt: automated high-throughput crystallization suited for membrane proteins and more.
Journal of structural and functional genomics 2012;13(2):63-9.
2009: Juergen Koepke; Elena Olkhova; Heike Angerer; Hannelore Müller; Guohong Peng; Hartmut Michel
High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: new insights into the active site and the proton transfer pathways.
Biochimica et biophysica acta 2009;1787(6):635-45.
2008: Katharina L Dürr; Juergen Koepke; Petra Hellwig; Hannelore Müller; Heike Angerer; Guohong Peng; Elena Olkhova; Oliver-Matthias H Richter; Bernd Ludwig; Hartmut Michel
A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate.
Journal of molecular biology 2008;384(4):865-77.
2007: Leif Barleben; Santosh Panjikar; Martin Ruppert; Juergen Koepke; Joachim Stöckigt
Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family.
The Plant cell 2007;19(9):2886-97.
2007: Juergen Koepke; Eva-Maria Krammer; Astrid R Klingen; Pierre Sebban; G Matthias Ullmann; Günter Fritzsch
pH modulates the quinone position in the photosynthetic reaction center from Rhodobacter sphaeroides in the neutral and charge separated states.
Journal of molecular biology 2007;371(2):396-409.
2007: Hélène Cheap; Júlia Tandori; Valérie Derrien; Mireille Benoit; Pedro de Oliveira; Juergen Koepke; Jérôme Lavergne; Peter Maroti; Pierre Sebban
Evidence for delocalized anticooperative flash induced proton binding as revealed by mutants at the M266His iron ligand in bacterial reaction centers.
Biochemistry 2007;46(15):4510-21.
2006: Xueyan Ma; Santosh Panjikar; Juergen Koepke; Elke Loris; Joachim Stöckigt
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins.
The Plant cell 2006;18(4):907-20.
2005: Vicky Katsemi; Christian Lücke; Juergen Koepke; Frank Löhr; Steffen Maurer; Günter Fritzsch; Heinz Rüterjans
Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme.
Biochemistry 2005;44(25):9022-33.
2005: Xueyan Ma; Juergen Koepke; Anja Bayer; Günter Fritzsch; Hartmut Michel; Joachim Stöckigt
Crystallization and preliminary X-ray analysis of native and selenomethionyl vinorine synthase from Rauvolfia serpentina.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 6):694-6.
2005: Juergen Koepke; Xueyan Ma; Günter Fritzsch; Hartmut Michel; Joachim Stöckigt
Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 6):690-3.
2005: Xueyan Ma; Juergen Koepke; Santosh Panjikar; Günter Fritzsch; Joachim Stöckigt
Crystal structure of vinorine synthase, the first representative of the BAHD superfamily.
The Journal of biological chemistry 2005;280(14):13576-83.
2005: Leif Barleben; Xueyan Ma; Juergen Koepke; Guohong Peng; Hartmut Michel; Joachim Stöckigt
Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons.
Biochimica et biophysica acta 2005;1747(1):89-92.
2004: Xueyan Ma; Juergen Koepke; Günter Fritzsch; Ralf Diem; Toni M Kutchan; Hartmut Michel; Joachim Stöckigt
Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family.
Biochimica et biophysica acta 2004;1702(1):121-4.
2004: Xueyan Ma; Juergen Koepke; Anja Bayer; Verena Linhard; Günter Fritzsch; Bin Zhang; Hartmut Michel; Joachim Stöckigt
Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily.
Biochimica et biophysica acta 2004;1701(1-2):129-32.
2003: Juergen Koepke; Eileen I Scharff; Christian Lücke; Heinz Rüterjans; Günter Fritzsch
Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 A resolution.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 10):1744-54.
2002: Juergen Koepke; Eileen I Scharff; Christian Lücke; Heinz Rüterjans; Günter Fritzsch
Atomic resolution crystal structure of squid ganglion DFPase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 1):1757-9.
2002: Günter Fritzsch; Juergen Koepke; Ralf Diem; Andreas Kuglstatter; Laura Baciou
Charge separation induces conformational changes in the photosynthetic reaction centre of purple bacteria.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 1):1660-3.
2001: Eileen I Scharff; Juergen Koepke; Günter Fritzsch; Christian Lücke; Heinz Rüterjans
Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris.
Structure (London, England : 1993) 2001;9(6):493-502.
2001: Eileen I Scharff; Christian Lücke; Günter Fritzsch; Juergen Koepke; Judith Hartleib; S Dierl; Heinz Rüterjans
Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):148-9.
2000: Carola Hunte; Juergen Koepke; Christian Lange; T Rossmanith; Hartmut Michel
Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Structure (London, England : 1993) 2000;8(6):669-84.
2000: Juergen Koepke; Ulrich Ermler; Eberhard Warkentin; G Wenzl; P Flecker
Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
Journal of molecular biology 2000;298(3):477-91.
2000: I P Chen; P Mathis; Juergen Koepke; Hartmut Michel
Uphill electron transfer in the tetraheme cytochrome subunit of the Rhodopseudomonas viridis photosynthetic reaction center: evidence from site-directed mutagenesis.
Biochemistry 2000;39(13):3592-602.