FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Makoto Hayashi

Research Profile

Procedures

Chemicals & Drugs

Living Beings

Physiology

Mutation

Anatomy

Concepts & Ideas

Drug Dose Response Relationship

Genes & Molecular Sequences

Lac Operon

Disorders

Co-author Network

Publications

TOP 3
Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman; Marilyn Aardema; Philippe Vanparys
ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study.
Masamitsu Honma; Makoto Hayashi
Comparison of in vitro micronucleus and gene mutation assay results for p53-competent versus p53-deficient human lymphoblastoid cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Makoto Hayashi (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
Mutation research 2012;744(1):111-6.
2012: Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman; Marilyn Aardema; Philippe Vanparys
ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study.
Mutation research 2012;744(1):12-9.
2011: Masamitsu Honma; Makoto Hayashi
Comparison of in vitro micronucleus and gene mutation assay results for p53-competent versus p53-deficient human lymphoblastoid cells.
Environmental and molecular mutagenesis 2011;52(5):373-84.
2011: Philippe Vanparys; Raffaella Corvi; Marilyn Aardema; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard Schechtman
ECVAM prevalidation of three cell transformation assays.
ALTEX 2011;28(1):56-9.
2011: Takeshi Morita; James T MacGregor; Makoto Hayashi
Micronucleus assays in rodent tissues other than bone marrow.
Mutagenesis 2011;26(1):223-30.
2010: Manabu Yasui; Naoki Koyama; Tomoko Koizumi; Kaori Senda-Murata; Yoshio Takashima; Makoto Hayashi; Kenji Sugimoto; Masamitsu Honma
Live cell imaging of micronucleus formation and development.
Mutation research 2010;692(1-2):12-8.
2009: Yoshio Takashima; Mayumi Sakuraba; Tomoko Koizumi; Hiroko Sakamoto; Makoto Hayashi; Masamitsu Honma
Dependence of DNA double strand break repair pathways on cell cycle phase in human lymphoblastoid cells.
Environmental and molecular mutagenesis 2009;50(9):815-22.
2009: Stefan Pfuhler; David Kirkland; Peter Kasper; Makoto Hayashi; Philippe Vanparys; Paul Carmichael; Stephen D Dertinger; David Eastmond; Azeddine Elhajouji; Cyrille Krul; Andreas Rothfuss; Gabriele Schoening; Andrew Smith; Guenter Speit; Claire Thomas; Jan van Benthem; Raffaella Corvi
Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Mutation research 2009;680(1-2):31-42.
2009: Takeshi Morita; Makoto Hayashi; Madoka Nakajima; Noriho Tanaka; David J Tweats; Kaoru Morikawa; Toshio Sofuni
Practical issues on the application of the GHS classification criteria for germ cell mutagens.
Regulatory toxicology and pharmacology : RTP 2009;55(1):52-68.
2008: Manabu Yasui; Emi Suenaga; Naoki Koyama; Chikahide Masutani; Fumio Hanaoka; Petr Gruz; Shinya Shibutani; Takehiko Nohmi; Makoto Hayashi; Masamitsu Honma
Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.
Journal of molecular biology 2008;377(4):1015-23.
2007: Yang Luan; Takayoshi Suzuki; Rajaguru Palanisamy; Yoshio Takashima; Hiroko Sakamoto; Mayumi Sakuraba; Tomoko Koizumi; Mika Saito; Hiroshi Matsufuji; Kazuo Yamagata; Teruhide Yamaguchi; Makoto Hayashi; Masamitsu Honma
Potassium bromate treatment predominantly causes large deletions, but not GC>TA transversion in human cells.
Mutation research 2007;619(1-2):113-23.
2007: Masamitsu Honma; Mayumi Sakuraba; Tomoko Koizumi; Yoshio Takashima; Hiroko Sakamoto; Makoto Hayashi
Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells.
DNA repair 2007;6(6):781-8.
2007: David Kirkland; Stefan Pfuhler; David Tweats; Marilyn Aardema; Raffaella Corvi; Firouz Darroudi; Azeddine Elhajouji; Hansruedi Glatt; Paul Hastwell; Makoto Hayashi; Peter Kasper; Stephan Kirchner; Anthony Lynch; Daniel Marzin; Daniela Maurici; Jean-Roch Meunier; Lutz Müller; Gerhard J Nohynek; James Parry; Elizabeth Parry; Veronique Thybaud; Raymond R Tice; Jan van Benthem; Philippe Vanparys; Paul White
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Mutation research 2007;628(1):31-55.
2007: Makoto Hayashi; James T MacGregor; David G Gatehouse; David Blakey; Stephen D Dertinger; Lilianne Abramsson-Zetterberg; Gopala Krishna; Takeshi Morita; Antonella Russo; Norihide Asano; Hiroshi Suzuki; Wakako Ohyama; Dave Gibson
In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.
Mutation research 2007;627(1):10-30.
2007: David Kirkland; Makoto Hayashi; David Jacobson-Kram; Peter Kasper; James T MacGregor; Lutz Müller; Yoshifumi Uno
Summary of major conclusions from the 4th IWGT, San Francisco, 9-10 September, 2005.
Mutation research 2007;627(1):5-9.
2007: Veronique Thybaud; Marilyn Aardema; J Clements; Kerry L Dearfield; S Galloway; Makoto Hayashi; David Jacobson-Kram; David Kirkland; James T MacGregor; Daniel Marzin; W Ohyama; M Schuler; H Suzuki; Errol Zeiger
Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.
Mutation research 2007;627(1):41-58.
2007: Makoto Hayashi; Masamitsu Honma
[Evaluation of in vivo genotoxicity of chemicals--development and application of rodent micronucleus assay].
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyūjo hōkoku = Bulletin of National Institute of Health Sciences 2007;(125):17-34.
2006: Naoki Koyama; Hiroko Sakamoto; Mayumi Sakuraba; Tomoko Koizumi; Yoshio Takashima; Makoto Hayashi; Hiroshi Matsufuji; Kazuo Yamagata; Shuichi Masuda; Naohide Kinae; Masamitsu Honma
Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells.
Mutation research 2006;603(2):151-8.
2005: Makoto Hayashi; Eiichi Kamata; Akihiko Hirose; Mika Takahashi; Takeshi Morita; Makoto Ema
In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals.
Mutation research 2005;588(2):129-35.
2005: Makoto Hayashi; Noriho Tanaka
[Genotoxicity of 43 existing food additives].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2005;46(5):177-84.
2004: Li Zhan; Hiroko Sakamoto; Mayumi Sakuraba; De Sheng Wu; Li Shi Zhang; Takayoshi Suzuki; Makoto Hayashi; Masamitsu Honma
Genotoxicity of microcystin-LR in human lymphoblastoid TK6 cells.
Mutation research 2004;557(1):1-6.
2003: Lutz Müller; David Blakey; Kerry L Dearfield; Sheila Galloway; Peggy Guzzie; Makoto Hayashi; Peter Kasper; David Kirkland; James T MacGregor; James M Parry; Leonard M Schechtman; Andrew Smith; Noriho Tanaka; David Tweats; Hiroshi Yamasaki
Strategy for genotoxicity testing and stratification of genotoxicity test results--report on initial activities of the IWGT Expert Group.
Mutation research 2003;540(2):177-81.
2003: Masamitsu Honma; Masako Izumi; Mayumi Sakuraba; Satoshi Tadokoro; Hiroko Sakamoto; Wensheng Wang; Fumio Yatagai; Makoto Hayashi
Deletion, rearrangement, and gene conversion; genetic consequences of chromosomal double-strand breaks in human cells.
Environmental and molecular mutagenesis 2003;42(4):288-98.
2002: Masamitsu Honma; Satoshi Tadokoro; Hiroko Sakamoto; Hideyuki Tanabe; Masanobu Sugimoto; Yasuhiro Furuichi; Takatomo Satoh; Toshio Sofuni; Makoto Goto; Makoto Hayashi
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.
Mutation research 2002;520(1-2):15-24.
2002: Takashi Omori; Masamitsu Honma; Makoto Hayashi; Yoriko Honda; Isao Yoshimura
A new statistical method for evaluation of L5178Ytk(+/-) mammalian cell mutation data using microwell method.
Mutation research 2002;517(1-2):199-208.
2002: Arihiro Kohara; Takayoshi Suzuki; Masamitsu Honma; Takashi Oomori; Tomohiko Ohwada; Makoto Hayashi
Dinitropyrenes induce gene mutations in multiple organs of the lambda/lacZ transgenic mouse (Muta Mouse).
Mutation research 2002;515(1-2):73-83.
2002: Arihiro Kohara; Takayoshi Suzuki; Masamitsu Honma; Tomohiko Ohwada; Makoto Hayashi
Mutagenicity of aristolochic acid in the lambda/lacZ transgenic mouse (MutaMouse).
Mutation research 2002;515(1-2):63-72.
2002: Yasuhiro Noda; Takayoshi Suzuki; Arihiro Kohara; Akira Hasegawa; Toshihisa Yotsuyanagi; Makoto Hayashi; Toshio Sofuni; Kenzo Yamanaka; Shoji Okada
In vivo genotoxicity evaluation of dimethylarsinic acid in MutaMouse.
Mutation research 2002;513(1-2):205-12.
2001: Masamitsu Honma; M Momose; Hiroko Sakamoto; Toshio Sofuni; Makoto Hayashi
Spindle poisons induce allelic loss in mouse lymphoma cells through mitotic non-disjunction.
Mutation research 2001;493(1-2):101-14.
2001: Arihiro Kohara; Takayoshi Suzuki; Masamitsu Honma; N Hirano; K Ohsawa; Tomohiko Ohwada; Makoto Hayashi
Mutation spectrum of o-aminoazotoluene in the cII gene of lambda/lacZ transgenic mice (MutaMouse).
Mutation research 2001;491(1-2):211-20.
2001: Akiyoshi Nishikawa; Takayoshi Suzuki; Ken-ichi Masumura; Fumio Furukawa; Makoto Miyauchi; Hideaki Nakamura; Hwa-Young Son; Takehiko Nohmi; Makoto Hayashi; Masao Hirose
Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis.
Journal of experimental & clinical cancer research : CR 2001;20(1):111-5.
2001: S Hamada; S Sutou; Takeshi Morita; Akihiro Wakata; S Asanami; S Hosoya; S Ozawa; K Kondo; M Nakajima; Hiroyasu Shimada; K Osawa; Y Kondo; Norihide Asano; S Sato; H Tamura; N Yajima; R Marshall; C Moore; David Blakey; Leonard M Schechtman; J L Weaver; D K Torous; R Proudlock; S Ito; C Namiki; Makoto Hayashi
Evaluation of the rodent micronucleus assay by a 28-day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)-Mammalian Mutagenicity Study Group (MMS).
Environmental and molecular mutagenesis 2001;37(2):93-110.
2000: Takayoshi Suzuki; X Wang; Y Miyata; K Saeki; Arihiro Kohara; Y Kawazoe; Makoto Hayashi; Toshio Sofuni
Hepatocarcinogen quinoline induces G:C to C:G transversions in the cII gene in the liver of lambda/lacZ transgenic mice (MutaMouse).
Mutation research 2000;456(1-2):73-81.
2000: Masamitsu Honma; M Momose; H Tanabe; Hiroko Sakamoto; Y Yu; J B Little; Toshio Sofuni; Makoto Hayashi
Requirement of wild-type p53 protein for maintenance of chromosomal integrity.
Molecular carcinogenesis 2000;28(4):203-14.
2000: T Itoh; Takayoshi Suzuki; Akiyoshi Nishikawa; Fumio Furukawa; Mika Takahashi; W Xue; Toshio Sofuni; Makoto Hayashi
In vivo genotoxicity of 2-amino-3,8-dimethylimidazo[4, 5-f]quinoxaline in lacI transgenic (Big Blue) mice.
Mutation research 2000;468(1):19-25.
2000: Toshio Sofuni; Makoto Hayashi; Takehiko Nohmi; Atsuko Matsuoka; Masami Yamada; Eiichi Kamata
Semi-quantitative evaluation of genotoxic activity of chemical substances and evidence for a biological threshold of genotoxic activity.
Mutation research 2000;464(1):97-104.
2000: Makoto Hayashi; James T MacGregor; D G Gatehouse; I D Adler; David Blakey; Stephen D Dertinger; G Krishna; Takeshi Morita; A Russo; S Sutou
In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring.
Environmental and molecular mutagenesis 2000;35(3):234-52.
2000: Akiyoshi Nishikawa; Fumio Furukawa; Ken-Ichiro Kasahara; S Ikezaki; T Itoh; Takayoshi Suzuki; K Uchida; M Kurihara; Makoto Hayashi; Naoki Miyata; Masao Hirose
Trans-4-hydroxy-2-nonenal, an aldehydic lipid peroxidation product, lacks genotoxicity in lacI transgenic mice.
Cancer letters 2000;148(1):81-6.
1999: Takayoshi Suzuki; Y Uno; K Idehara; T Baba; J Maniwa; A Ohkouchi; X Wang; Makoto Hayashi; Toshio Sofuni; M Tsuruoka; H Miyajima; K Kondo
Procarbazine genotoxicity in the MutaMouse; strong clastogenicity and organ-specific induction of lacZ mutations.
Mutation research 1999;444(2):269-81.
1999: Minoru Saitoh; Takashi Umemura; Yasushi Kawasaki; J Momma; Yuko Matsushima; Kazue Sakemi; Kazuo Isama; S Kitajima; Y Ogawa; Ryuichi Hasegawa; Takayoshi Suzuki; Makoto Hayashi; Tohru Inoue; Yasuo Ohno; Toshio Sofuni; Yuji Kurokawa; Mitsuhiro Tsuda
Toxicity study of a rubber antioxidant, mixture of 2-mercaptomethylbenzimidazoles, by repeated oral administration to rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(7):777-87.
1999: Atsuko Matsuoka; K Matsuura; Hiroko Sakamoto; Makoto Hayashi; Toshio Sofuni
A proposal for a simple way to distinguish aneugens from clastogens in the in vitro micronucleus test.
Mutagenesis 1999;14(4):385-9.
1999: Masamitsu Honma; L Z Zhang; Hiroko Sakamoto; Masayasu Ozaki; Kenji Takeshita; M Momose; Makoto Hayashi; Toshio Sofuni
The need for long-term treatment in the mouse lymphoma assay.
Mutagenesis 1999;14(1):23-9.
1999: Masamitsu Honma; Makoto Hayashi; Hiroyasu Shimada; N Tanaka; S Wakuri; T Awogi; K I Yamamoto; N Kodani; Y Nishi; M Nakadate; Toshio Sofuni
Evaluation of the mouse lymphoma tk assay (microwell method) as an alternative to the in vitro chromosomal aberration test.
Mutagenesis 1999;14(1):5-22.
1998: Atsuko Matsuoka; K Matsuura; Hiroko Sakamoto; Makoto Hayashi; Toshio Sofuni
Spindle disturbances induced by benzo[a]pyrene and 7, 12-dimethylbenz[a]anthracene in a Chinese hamster cell line (V79-MZ) and the stability of the numerical chromosome aberrations that follow.
Mutation research 1998;419(1-3):1-12.
1998: X Wang; Takayoshi Suzuki; T Itoh; Masamitsu Honma; Akiyoshi Nishikawa; Fumio Furukawa; Mika Takahashi; Makoto Hayashi; T Kato; Toshio Sofuni
Specific mutational spectrum of dimethylnitrosamine in the lacI transgene of Big Blue C57BL/6 mice.
Mutagenesis 1998;13(6):625-30.
1998: Makoto Hayashi; T Ueda; K Uyeno; K Wada; Naohide Kinae; K Saotome; Noriho Tanaka; A Takai; Y F Sasaki; Norihide Asano; Toshio Sofuni; Y Ojima
Development of genotoxicity assay systems that use aquatic organisms.
Mutation research 1998;399(2):125-33.
1998: Takayoshi Suzuki; Y Miyata; K Saeki; Y Kawazoe; Makoto Hayashi; Toshio Sofuni
In vivo mutagenesis by the hepatocarcinogen quinoline in the lacZ transgenic mouse: evidence for its in vivo genotoxicity.
Mutation research 1998;412(2):161-6.
1998: Takeshi Morita; Makoto Hayashi
1,4-Dioxane is not mutagenic in five in vitro assays and mouse peripheral blood micronucleus assay, but is in mouse liver micronucleus assay.
Environmental and molecular mutagenesis 1998;32(3):269-80.
1998: Akihiro Wakata; Y Miyamae; S Sato; T Suzuki; Takeshi Morita; Norihide Asano; T Awogi; K Kondo; Makoto Hayashi
Evaluation of the rat micronucleus test with bone marrow and peripheral blood: summary of the 9th collaborative study by CSGMT/JEMS. MMS. Collaborative Study Group for the Micronucleus Test. Environmental Mutagen Society of Japan. Mammalian Mutagenicity Study Group.
Environmental and molecular mutagenesis 1998;32(1):84-100.
1997: Takayoshi Suzuki; Makoto Hayashi; X Wang; K Yamamoto; T Ono; B C Myhr; Toshio Sofuni
A comparison of the genotoxicity of ethylnitrosourea and ethyl methanesulfonate in lacZ transgenic mice (Muta Mouse).
Mutation research 1997;395(1):75-82.
1997: Atsuko Matsuoka; Masayasu Ozaki; Kenji Takeshita; Hiroko Sakamoto; H R Glatt; Makoto Hayashi; Toshio Sofuni
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
Mutagenesis 1997;12(5):365-72.
1997: Akiyoshi Nishikawa; Fumio Furukawa; Ken-Ichiro Kasahara; In Seon Lee; Takayoshi Suzuki; Makoto Hayashi; Toshio Sofuni; Mika Takahashi
Comparative study on organ-specificity of tumorigenicity, mutagenicity and cell proliferative activity induced by dimethylnitrosamine in Big Blue mice.
Cancer letters 1997;117(2):143-7.
1997: Masamitsu Honma; L S Zhang; Makoto Hayashi; Kenji Takeshita; Y Nakagawa; N Tanaka; Toshio Sofuni
Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells.
Molecular and cellular biology 1997;17(8):4774-81.
1997: Masamitsu Honma; Makoto Hayashi; Peter Hackman; Toshio Sofuni
Chlorambucil-induced structural changes in the gpt gene of AS52 cells.
Mutation research 1997;389(2-3):199-205.
1997: Masamitsu Honma; Makoto Hayashi; Toshio Sofuni
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
Mutation research 1997;374(1):89-98.
1997: Takeshi Morita; Norihide Asano; T Awogi; Y F Sasaki; S Sato; Hiroyasu Shimada; S Sutou; T Suzuki; Akihiro Wakata; Toshio Sofuni; Makoto Hayashi
Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group.
Mutation research 1997;389(1):3-122.
1997: Takayoshi Suzuki; S Itoh; N Takemoto; N Yajima; M Miura; Makoto Hayashi; Hiroyasu Shimada; Toshio Sofuni
Ethyl nitrosourea and methyl methanesulfonate mutagenicity in sperm and testicular germ cells of lacZ transgenic mice (Muta Mouse).
Mutation research 1997;388(2-3):155-63.
1996: M Matsui; K Matsui; Yasushi Kawasaki; Y Oda; T Noguchi; Y Kitagawa; M Sawada; Makoto Hayashi; Takehiko Nohmi; K Yoshihira; M Ishidate; Toshio Sofuni
Evaluation of the genotoxicity of stevioside and steviol using six in vitro and one in vivo mutagenicity assays.
Mutagenesis 1996;11(6):573-9.
1996: L S Zhang; Masamitsu Honma; Atsuko Matsuoka; Takayoshi Suzuki; Toshio Sofuni; Makoto Hayashi
Chromosome painting analysis of spontaneous and methyl methanesulfonate-induced trifluorothymidine-resistant L5178Y cell colonies.
Mutation research 1996;370(3-4):181-90.
1996: Atsuko Matsuoka; K Yamakage; H Kusakabe; S Wakuri; M Asakura; T Noguchi; T Sugiyama; Hiroyasu Shimada; S Nakayama; Y Kasahara; Y Takahashi; K F Miura; M Hatanaka; M Ishidate; T Morita; K Watanabe; M Hara; K Odawara; N Tanaka; Makoto Hayashi; Toshio Sofuni
Re-evaluation of chromosomal aberration induction on nine mouse lymphoma assay "unique positive' NTP carcinogens.
Mutation research 1996;369(3-4):243-52.
1996: Takayoshi Suzuki; Makoto Hayashi; M Ochiai; K Wakabayashi; T Ushijima; T Sugimura; M Nagao; Toshio Sofuni
Organ variation in the mutagenicity of MeIQ in Big Blue lacI transgenic mice.
Mutation research 1996;369(1-2):45-9.
1996: Toshio Sofuni; Masamitsu Honma; Makoto Hayashi; Hiroyasu Shimada; N Tanaka; S Wakuri; T Awogi; K I Yamamoto; Y Nishi; M Nakadate
Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study.
Mutagenesis 1996;11(4):349-55.
1996: Toshio Sofuni; Takayoshi Suzuki; Makoto Hayashi
Initial consideration for use of transgenic mutation assays in a regulatory submission.
Environmental and molecular mutagenesis 1996;28(4):443-6.
1996: Takayoshi Suzuki; T Itoh; Makoto Hayashi; Y Nishikawa; S Ikezaki; Fumio Furukawa; Mika Takahashi; Toshio Sofuni
Organ variation in the mutagenicity of dimethylnitrosamine in Big Blue mice.
Environmental and molecular mutagenesis 1996;28(4):348-53.
1995: Makoto Hayashi; Toshio Sofuni
A reaction to 'A sequential approach to testing with the rodent bone marrow micronucleus assay'.
Mutation research 1995;331(1):173-4.
1995: L S Zhang; Masamitsu Honma; Makoto Hayashi; Takayoshi Suzuki; Atsuko Matsuoka; Toshio Sofuni
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
Mutation research 1995;347(3-4):105-15.
1995: Makoto Hayashi; Toshio Sofuni
The need for three dose levels to detect genotoxic chemicals in in vivo rodent assays.
Mutation research 1995;327(1-2):247-51.
1995: Takayoshi Suzuki; Makoto Hayashi; A Hakura; A O Asita; Y Kodama; Masamitsu Honma; Toshio Sofuni
Combination effects of clastogens in the mouse peripheral blood micronucleus assay.
Mutagenesis 1995;10(1):31-6.
1994: Makoto Hayashi; Raymond R Tice; James T MacGregor; D Anderson; D H Blakey; M Kirsh-Volders; F B Oleson; F Pacchierotti; F Romagna; Hiroyasu Shimada
In vivo rodent erythrocyte micronucleus assay.
Mutation research 1994;312(3):293-304.
1994: Takayoshi Suzuki; Makoto Hayashi; Toshio Sofuni
Initial experiences and future directions for transgenic mouse mutation assays.
Mutation research 1994;307(2):489-94.
1994: Makoto Hayashi; J Mäki-Paakkanen; H Tanabe; Masamitsu Honma; Takayoshi Suzuki; Atsuko Matsuoka; H Mizusawa; Toshio Sofuni
Isolation of micronuclei from mouse blood and fluorescence in situ hybridization with a mouse centromeric DNA probe.
Mutation research 1994;307(1):245-51.
1994: M Watanabe; Atsuko Matsuoka; N Yamazaki; Makoto Hayashi; T Deguchi; Takehiko Nohmi; Toshio Sofuni
New sublines of Chinese hamster CHL stably expressing human NAT1 or NAT2 N-acetyltransferases or Salmonella typhimurium O-acetyltransferase: comparison of the sensitivities to nitroarenes and aromatic amines using the in vitro micronucleus test.
Cancer research 1994;54(7):1672-7.
1994: Atsuko Matsuoka; James Tucker; Makoto Hayashi; N Yamazaki; Toshio Sofuni
Chromosome painting analysis of X-ray-induced aberrations in human lymphocytes in vitro.
Mutagenesis 1994;9(2):151-5.
1994: Masamitsu Honma; H Mizusawa; K Sasaki; Makoto Hayashi; T Ohno; N Tanaka; Toshio Sofuni
Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation.
Mutation research 1994;304(2):167-79.
1994: Makoto Hayashi; S Hashimoto; Y Sakamoto; C Hamada; Toshio Sofuni; I Yoshimura
Statistical analysis of data in mutagenicity assays: rodent micronucleus assay.
Environmental health perspectives 1994;102 Suppl 1():49-52.
1993: Masamitsu Honma; E Kataoka; K Ohnishi; T Kikuno; Makoto Hayashi; Toshio Sofuni; H Mizusawa
Detection of recombinational mutations in cultured human cells by Southern blot analysis with minisatellite DNA probes.
Mutation research 1993;286(2):165-72.
1993: Takayoshi Suzuki; Makoto Hayashi; Toshio Sofuni; B C Myhr
The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice.
Mutation research 1993;285(2):219-24.
1992: Atsuko Matsuoka; N Yamazaki; Takayoshi Suzuki; Makoto Hayashi; Toshio Sofuni
Evaluation of the micronucleus test using a Chinese hamster cell line as an alternative to the conventional in vitro chromosomal aberration test.
Mutation research 1992;272(3):223-36.
1992: Makoto Hayashi; H Norppa; Toshio Sofuni; M Ishidate
Flow cytometric micronucleus test with mouse peripheral erythrocytes.
Mutagenesis 1992;7(4):257-64.
1992: Makoto Hayashi; H Norppa; Toshio Sofuni; M Ishidate
Mouse bone marrow micronucleus test using flow cytometry.
Mutagenesis 1992;7(4):251-6.
1992: Makoto Hayashi; Y Kodama; T Awogi; Takayoshi Suzuki; A O Asita; Toshio Sofuni
The micronucleus assay using peripheral blood reticulocytes from mitomycin C- and cyclophosphamide-treated rats.
Mutation research 1992;278(2-3):209-13.
1992: Takayoshi Suzuki; K Tamai; Y Kodama; A O Asita; Atsuko Matsuoka; Toshio Sofuni; M Kurita; H Ohtsuki; T Hiwatashi; Makoto Hayashi
Micronucleus induction in mouse peripheral reticulocytes by 7,12-dimethylbenz[a]anthracene.
Mutation research 1992;278(2-3):169-73.
1992: A O Asita; Makoto Hayashi; Y Kodama; Atsuko Matsuoka; Takayoshi Suzuki; Toshio Sofuni
Micronucleated reticulocyte induction by ethylating agents in mice.
Mutation research 1992;271(1):29-37.
1991: M Nakadate; Makoto Hayashi; Toshio Sofuni; E Kamata; Y Aida; T Osada; T Ishibe; Y Sakamura; M Ishidate
The expert system for toxicity prediction of chemicals based on structure-activity relationship.
Environmental health perspectives 1991;96():77-9.
1991: Makoto Hayashi; M Nakadate; T Osada; T Ishibe; S Tanaka; A Maekawa; Toshio Sofuni; Y Nakata; N Kanoh; S Hashiba
A fact database for toxicological data at the National Institute of Hygienic Sciences, Japan.
Environmental health perspectives 1991;96():57-60.
1991: Makoto Hayashi; Toshio Sofuni; T Morita
Simulation study of the effects of multiple treatments in the mouse bone marrow micronucleus test.
Mutation research 1991;252(3):281-7.
1989: Makoto Hayashi; T Sofuni; Y Kodama; M Ishidate; H Tamura
Micronucleus test with 1-beta-D-arabinofuranosylcytosine administered by intraperitoneal injection and oral gavage.
Mutation research 1989;223(4):345-8.
1989: Makoto Hayashi; S Sutou; H Shimada; S Sato; Y F Sasaki; Akihiro Wakata
Difference between intraperitoneal and oral gavage application in the micronucleus test. The 3rd collaborative study by CSGMT/JEMS.MMS. Collaborative Study Group for the Micronucleus Test/Mammalian Mutagenesis Study Group of the Environmental Mutagen Society of Japan.
Mutation research 1989;223(4):329-44.
1989: Makoto Hayashi; I Yoshimura; T Sofuni; M Ishidate
A procedure for data analysis of the rodent micronucleus test involving a historical control.
Environmental and molecular mutagenesis 1989;13(4):347-56.
1988: Makoto Hayashi; M Kishi; Toshio Sofuni; M Ishidate
Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1988;26(6):487-500.