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Ulrich Steidl

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Oligonucleotide Array Sequence Analysis

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Britta Will; Tihomira I Todorova; Amit Verma; Thomas O Vogler; Laura Barreyro; Boris Bartholdy; Tushar D Bhagat; Maria E Figueroa; Francine Garrett-Bakelman; Jillian Mayer; Ari Melnick; Ujunwa C Okoye-Okafor; Ashley Pandolfi; Michael Roth; Robert F Stanley; Ulrich Steidl
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.
Tushar D Bhagat; Kavi Bhatia; Markus Bitzer; Jacqueline Boultwood; Gisela Caceres; Shanisha Gordon; Krishna Gundabolu; Xiaohong Jing; Tomasz Jodlowski; Wenjun Ju; Suman Kambhampati; Paraic Kenny; Rachel Kessel; Alan List; Gang Liu; Ioannis Mantzaris; Andrea Pellagatti; Rahul Polineni; Lubomir Sokol; Ulrich Steidl; Cy Stein; Roni Tamari; Yiting Yu; Li Zhou; Amit Verma
miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling.
Yiting Yu; Amittha Wickrema; Sandeep Wontakal; Andrew Artz; Kathleen Bathon; Tushar Bhagat; Sanchari Bhattacharyya; Bennett Caces; Jessy Cartier; David Ebenezer; Orsolya Giricz; Oleg Gligich; Lucy Godley; John M Greally; Hui Liu; Shahina Maqbool; Yongkai Mo; Sangeeta Nischal; Arthur I Skoultchi; Ulrich Steidl; Sriram Sundaravel; Masako Suzuki; Amit Verma
High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.

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2013: Britta Will; Tihomira I Todorova; Amit Verma; Thomas O Vogler; Laura Barreyro; Boris Bartholdy; Tushar D Bhagat; Maria E Figueroa; Francine Garrett-Bakelman; Jillian Mayer; Ari Melnick; Ujunwa C Okoye-Okafor; Ashley Pandolfi; Michael Roth; Robert F Stanley; Ulrich Steidl
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.
Nature immunology 2013;14(5):437-45.
2013: Tushar D Bhagat; Kavi Bhatia; Markus Bitzer; Jacqueline Boultwood; Gisela Caceres; Shanisha Gordon; Krishna Gundabolu; Xiaohong Jing; Tomasz Jodlowski; Wenjun Ju; Suman Kambhampati; Paraic Kenny; Rachel Kessel; Alan List; Gang Liu; Ioannis Mantzaris; Andrea Pellagatti; Rahul Polineni; Lubomir Sokol; Ulrich Steidl; Cy Stein; Roni Tamari; Yiting Yu; Li Zhou; Amit Verma
miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling.
Blood 2013;121(15):2875-81.
2013: Yiting Yu; Amittha Wickrema; Sandeep Wontakal; Andrew Artz; Kathleen Bathon; Tushar Bhagat; Sanchari Bhattacharyya; Bennett Caces; Jessy Cartier; David Ebenezer; Orsolya Giricz; Oleg Gligich; Lucy Godley; John M Greally; Hui Liu; Shahina Maqbool; Yongkai Mo; Sangeeta Nischal; Arthur I Skoultchi; Ulrich Steidl; Sriram Sundaravel; Masako Suzuki; Amit Verma
High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.
The Journal of biological chemistry 2013;288(13):8805-14.
2013: Christoph J Heuck; Caroline Hu; Shahper Khan; Shahina Maqbool; Richard Meagher; Jayesh Mehta; Sangeeta Nischal; Samir Parekh; Natalie Pulliam; Frederic Reu; Carolina Schinke; Tushar Bhagat; Sanchari Bhattacharyya; Grigoris Chrysofakis; John Greally; Krishna Gundabolu; Ulrich Steidl; Masako Suzuki; Joseph Tariman; Amit Verma; Eric Vickrey; Yiting Yu; Li Zhou; Seema B Singhal
Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2966-75.
2013: Ashley Pandolfi; Laura Barreyro; Ulrich Steidl
Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells.
Stem cells translational medicine 2013;2(2):143-50.
2013: Sangeeta Nischal; Animesh Pardanani; Davendra Sohal; Ulrich Steidl; Masako Suzuki; Britta Will; Yiting Yu; Li Zhou; Tushar D Bhagat; Sanchari Bhattacharyya; Maximilian Christopeit; John M Greally; Jaroslaw P Maciejewski; Michael McDevitt; Ari M Melnick; Yongkai Mo; Alison R Moliterno; Amit Verma
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.
Cancer research 2013;73(3):1076-85.
2012: Ingmar Bruns; Sebastian Büst; Ron-Patrick Cadeddu; Akos Czibere; Roland Fenk; Johannes C Fischer; Julia Fröbel; Stefanie Geyh; Ali-Nuri Hünerlitürkoglu; Marcus Jäger; Guido Kobbe; Frederik Roels; Frank A Schildberg; Thomas Schroeder; Ulrich Steidl; Andreas Trumpp; Christian Matthias Wilk; Christoph Zilkens; Fabian Zohren; Benedikt Brors; Ines Brueckmann; Rainer Haas
Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells.
Blood 2012;120(13):2620-30.
2012: Britta Will; B Hilda Ye; Yiting Yu; Li Zhou; Thomas O Vogler; Laura Barreyro; Susanna Ben-Neriah; Tushar D Bhagat; Sanchari Bhattacharyya; Jacqueline Boultwood; John M Greally; Christoph Heuck; Alan F List; Jaroslaw Maciejewski; Christine McMahon; Yonkai Mo; Cristina Montagna; Samir Parekh; Andrea Pellagatti; Carolina Schinke; Lewis Silverman; Christian Steidl; Ulrich Steidl; Roni Tamari; Amit Verma
Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.
Blood 2012;120(10):2076-86.
2012: Masahiro Kawahara; Ari Melnick; Constantine S Mitsiades; Ujunwa C Okoye-Okafor; Ashley Pandolfi; Michael Roth; Laura Barreyro; Boris Bartholdy; Maria E Figueroa; Tihomira I Todorova; Britta Will; Ulrich Steidl
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.
Cancer cell 2012;22(2):194-208.
2012: Laura Barreyro; Boris Bartholdy; Susana Ben-Neriah; Jacqueline Boultwood; Larry Cripe; Hugo F Fernandez; Peter L Greenberg; Rhett P Ketterling; Constantine S Mitsiades; Cristina Montagna; Elisabeth Paietta; Samir Parekh; Andrea Pellagatti; Robert F Stanley; Christian Steidl; Martin S Tallman; Tihomira I Todorova; Amit Verma; Britta Will; Li Zhou; Ulrich Steidl
Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.
Blood 2012;120(6):1290-8.
2012: Michael Roth; Guillermo Simkin; Roni Tamari; Amit Verma; Britta Will; Laura Barreyro; Boris Bartholdy; Constantine S Mitsiades; Swathi Narayanagari; Ulrich Steidl
Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation.
Blood 2012;120(2):386-94.
2012: Sabrina A Volpi; Uwe Werling; Britta Will; Sanjukta Chatterjee; Winfried Edelman; Ann J Feeney; Rabih Hassan; Harry Hou; Zhongliang Ju; Sergio Roa; Matthew D Scharff; Ulrich Steidl; Jiyoti Verma-Gaur; Barbara K Birshtein
Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(6):2556-66.
2012: Kai B Kaufmann; Sarah Kayser; Konrad Aumann; Ruzhica Bogeska; Lucas Ganzenmüller; Monika Gothwal; Albert Gründer; Thomas Günther; Tobias Hadlich; Manfred Jung; Jonas S Jutzi; Kien-Binh Pham; Alessandro Rambaldi; Brigitte Schlegelberger; Roland Schüle; Thalia S Seeger; Ulrich Steidl; Doris Steinemann; Julia M Wagner; Julius Wehrle; Martin Werner; Britta Will; Heike L Pahl
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.
The Journal of experimental medicine 2012;209(1):35-50.
2011: Li Zhou; Amittha Wickrema; Vijay Yajnik; Yiting Yu; Jinghang Zhang; Omar Abdel-Wahab; Cristina Alencar; Tushar Bhagat; Jacqueline Boultwood; Melissa Fazzari; Maria Figueroa; Ellen Freidman; Steven D Gore; John M Greally; Christoph Hueck; Suman Kambhampati; Ross Levine; Christine McMahon; Ari Melnick; Yongkai Mo; Sangeeta Nischal; Joanna Opalinska; Simrit Parmar; Andrea Pellagatti; Leonidas C Platanias; Yogen Sauthararajah; Davendra Sohal; Ulrich Steidl; Masako Suzuki; Amit Verma
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.
The Journal of biological chemistry 2011;286(28):25211-23.
2011: Sandeep N Wontakal; Deyou Zheng; Xingyi Guo; Milind C Mahajan; Debasish Raha; Minyi Shi; Michael Snyder; Ulrich Steidl; Sherman Weissman; Britta Will; Arthur I Skoultchi
A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.
PLoS genetics 2011;7(6):e1001392.
2011: Christian Steidl; Sohrab P Shah; Bruce W Woolcock; Lixin Rui; Masahiro Kawahara; Pedro Farinha; Nathalie A Johnson; Yongjun Zhao; Adele Telenius; Susana Ben Neriah; Andrew McPherson; Barbara Meissner; Ujunwa C Okoye; Arjan Diepstra; Anke Van den Berg; Mark Sun; Gillian Leung; Steven J Jones; Joseph Michael Connors; David Huntsman; Kerry J Savage; Lisa M Rimsza; Douglas E Horsman; Louis M Staudt; Ulrich Steidl; Marco A Marra; Randy D Gascoyne
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers.
Nature 2011;471(7338):377-81.
2011: Li Zhou; Christine McMahon; Tushar Bhagat; Cristina Alencar; Yiting Yu; Melissa Fazzari; Davendra Sohal; Christoph Heuck; Krishna Gundabolu; Chun Ng; Yongkai Mo; Wa Shen; Amittha Wickrema; Guanghui Kong; Ellen Friedman; Lubomir Sokol; Ioannis Mantzaris; Giannis Mantzaris; Andrea Pellagatti; Jacqueline Boultwood; Leonidas C Platanias; Ulrich Steidl; Lei Yan; Jonathan M Yingling; Michael M Lahn; Alan List; Markus Bitzer; Amit Verma
Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase.
Cancer research 2011;71(3):955-63.
2010: Britta Will; Ulrich Steidl
Multi-parameter fluorescence-activated cell sorting and analysis of stem and progenitor cells in myeloid malignancies.
Best practice & research. Clinical haematology 2010;23(3):391-401.
2010: Karen B O'Brien; Meritxell Alberich-Jordà; Neelu Yadav; Olivier Kocher; Annalisa Diruscio; Alexander Ebralidze; Elena Levantini; Natasha J L Sng; Manoj Bhasin; Tyler Caron; Daehoon Kim; Ulrich Steidl; Gang Huang; Balázs Halmos; Scott J Rodig; Mark T Bedford; Daniel G Tenen; Susumu Kobayashi
CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells.
Development (Cambridge, England) 2010;137(13):2147-56.
2010: Mirle Schemionek; Christian Elling; Ulrich Steidl; Nicole Bäumer; Ashley Hamilton; Tilmann Spieker; Joachim R Göthert; Martin Stehling; Amy Wagers; Claudia S Huettner; Daniel G Tenen; Lara Tickenbrock; Wolfgang E Berdel; Hubert Serve; Tessa L Holyoake; Carsten Müller-Tidow; Steffen Koschmieder
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.
Blood 2010;115(16):3185-95.
2010: Britta Will; Tanya Siddiqi; Meritxell Alberich Jordà; Takeshi Shimamura; Katarina Luptakova; Philipp B Staber; Daniel B Costa; Ulrich Steidl; Daniel G Tenen; Susumu Kobayashi
Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.
Blood 2010;115(14):2901-9.
2009: Britta Will; Masahiro Kawahara; Julia P Luciano; Ingmar Bruns; Samir Parekh; Connie L Erickson-Miller; Manuel A Aivado; Amit Verma; Ulrich Steidl
Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome.
Blood 2009;114(18):3899-908.
2009: Wolf C Prall; Akos Czibere; Franck Grall; Dimitrios Spentzos; Ulrich Steidl; Aristoteles Giagounidis; Andrea Kuendgen; Hasan Otu; Astrid Rong; Towia Libermann; Ulrich Germing; Norbert Gattermann; Rainer Haas; Manuel Aivado
Differential gene expression of bone marrow-derived CD34+ cells is associated with survival of patients suffering from myelodysplastic syndrome.
International journal of hematology 2009;89(2):173-87.
2008: Alexander K Ebralidze; Florence C Guibal; Ulrich Steidl; Pu Zhang; Sanghoon Lee; Boris Bartholdy; Meritxell Alberich Jorda; Victoria Petkova; Frank Rosenbauer; Gang Huang; Tajhal Dayaram; Johanna Klupp; Karen B O'Brien; Britta Will; Maarten Hoogenkamp; Katherine L B Borden; Constanze Bonifer; Daniel G Tenen
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Genes & development 2008;22(15):2085-92.
2008: Ingmar Bruns; Ulrich Steidl; Johannes C Fischer; Akos Czibere; Guido Kobbe; Sascha Raschke; Raminder Singh; Roland Fenk; Michael Rosskopf; Sabrina Pechtel; Arndt von Haeseler; Peter Wernet; Daniel G Tenen; Rainer Haas; Ralf Kronenwett
Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor.
Haematologica 2008;93(3):347-55.
2007: Ulrich Steidl; Christian Steidl; Alexander Ebralidze; Bjoern Chapuy; Hye-Jung Han; Britta Will; Frank Rosenbauer; Annegret Becker; Katharina Wagner; Steffen Koschmieder; Susumu Kobayashi; Daniel B Costa; Thomas Schulz; Karen B O'Brien; Roel G W Verhaak; Ruud Delwel; Detlef Haase; Lorenz Trümper; Jürgen Krauter; Terumi Kohwi-Shigematsu; Frank Griesinger; Daniel G Tenen
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.
The Journal of clinical investigation 2007;117(9):2611-20.
2007: Judith Neukirchen; A Meier; Astrid Rohrbeck; G Garcia-Pardillos; Ulrich Steidl; Roland Fenk; Rainer Haas; Ralf Kronenwett; Ulrich-Peter Rohr
The proteasome inhibitor bortezomib acts differently in combination with p53 gene transfer or cytotoxic chemotherapy on NSCLC cells.
Cancer gene therapy 2007;14(4):431-9.
2007: Manuel Aivado; Dimitrios Spentzos; Ulrich Germing; Gil Alterovitz; Xiao-Ying Meng; Franck Grall; Aristoteles Giagounidis; Giannoula Klement; Ulrich Steidl; Hasan H Otu; Akos Czibere; Wolf C Prall; Christof Iking-Konert; Michelle Shayne; Marco F Ramoni; Norbert Gattermann; Rainer Haas; Constantine S Mitsiades; Eric T Fung; Towia Libermann
Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1307-12.
2006: Susumu Kobayashi; Takeshi Shimamura; Stefano Monti; Ulrich Steidl; Christopher J Hetherington; April M Lowell; Todd R Golub; Matthew Meyerson; Daniel G Tenen; Geoffrey I Shapiro; Balazs Halmos
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling.
Cancer research 2006;66(23):11389-98.
2006: Nina Rehfeld; Helene Geddert; Abedelsalam Atamna; Helmut E Gabbert; Ulrich Steidl; Roland Fenk; Ralf Kronenwett; Rainer Haas; Ulrich-Peter Rohr
Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(11):2232-8.
2006: Ulrich Steidl; Frank Rosenbauer; Roel G W Verhaak; Xuesong Gu; Alexander Ebralidze; Hasan H Otu; Steffen Klippel; Christian Steidl; Ingmar Bruns; Daniel B Costa; Katharina Wagner; Manuel Aivado; Guido Kobbe; Peter J M Valk; Emmanuelle Passegué; Towia Libermann; Ruud Delwel; Daniel G Tenen
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Nature genetics 2006;38(11):1269-77.
2006: Roland Fenk; Nadine Hieronimus; Ulrich Steidl; Ingmar Bruns; Thorsten Graef; Fabian Zohren; Leilani Ruf; Rainer Haas; Guido Kobbe
Sustained G-CSF plasma levels following administration of pegfilgrastim fasten neutrophil reconstitution after high-dose chemotherapy and autologous blood stem cell transplantation in patients with multiple myeloma.
Experimental hematology 2006;34(10):1296-302.
2006: Ralf Kronenwett; Thorsten Graef; Frank Neumann; Sabrina Pechtel; Ulrich Steidl; Elena Diaz-Blanco; Rainer Haas
Absence of the JAK2 mutation V617F in CD34+ hematopoietic stem and progenitor cells from patients with BCR-ABL-positive CML in chronic phase and blast crisis.
Leukemia research 2006;30(10):1323-4.
2006: Ingmar Bruns; Ulrich Steidl; Ralf Kronenwett; Roland Fenk; Thorsten Graef; Ulrich-Peter Rohr; Frank Neumann; Johannes Fischer; Christof Scheid; Kai Hübel; Rainer Haas; Guido Kobbe
A single dose of 6 or 12 mg of pegfilgrastim for peripheral blood progenitor cell mobilization results in similar yields of CD34+ progenitors in patients with multiple myeloma.
Transfusion 2006;46(2):180-5.
2006: Nina Rehfeld; Helene Geddert; Abedelsalam Atamna; Astrid Rohrbeck; Guillermo Garcia; Slawomir Kliszewski; Judith Neukirchen; Ingmar Bruns; Ulrich Steidl; Roland Fenk; Helmut E Gabbert; Ralf Kronenwett; Rainer Haas; Ulrich-Peter Rohr
The influence of the pituitary tumor transforming gene-1 (PTTG-1) on survival of patients with small cell lung cancer and non-small cell lung cancer.
Journal of carcinogenesis 2006;5():4.
2006: Frank Rosenbauer; Bronwyn M. Owens; Li Yu; Joseph R Tumang; Ulrich Steidl; Jeffery L Kutok; Linda K Clayton; Katharina Wagner; Marina Scheller; Hiromi Iwasaki; Chunhui Liu; Björn Hackanson; Koichi Akashi; Achim Leutz; Thomas L Rothstein; Christoph Plass; Daniel G Tenen
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Nature genetics 2006;38(1):27-37.
2005: Frank Rosenbauer; Steffen Koschmieder; Ulrich Steidl; Daniel G Tenen
Effect of transcription-factor concentrations on leukemic stem cells.
Blood 2005;106(5):1519-24.
2005: Ralf Kronenwett; Ulf Butterweck; Ulrich Steidl; Slawomir Kliszewski; Frank Neumann; Simone Bork; Elena Diaz Blanco; Nicole Roes; Thorsten Graef; Benedikt Brors; Roland Eils; Christian Maercker; Guido Kobbe; Norbert Gattermann; Rainer Haas
Distinct molecular phenotype of malignant CD34(+) hematopoietic stem and progenitor cells in chronic myelogenous leukemia.
Oncogene 2005;24(34):5313-24.
2005: Roland Fenk; Peter Schneider; Martin Kropff; A N Huenerlituerkoglu; Ulrich Steidl; Carlo Aul; Barbara Hildebrandt; Rainer Haas; Axel Heyll; Guido Kobbe
High-dose idarubicin, cyclophosphamide and melphalan as conditioning for autologous stem cell transplantation increases treatment-related mortality in patients with multiple myeloma: results of a randomised study.
British journal of haematology 2005;130(4):588-94.
2005: Ulrich-Peter Rohr; Florian Heyd; Judith Neukirchen; Marc-Andre Wulf; Iris Queitsch; Gabriele Kroener-Lux; Ulrich Steidl; Roland Fenk; Rainer Haas; Ralf Kronenwett
Quantitative real-time PCR for titration of infectious recombinant AAV-2 particles.
Journal of virological methods 2005;127(1):40-5.
2005: Steffen Koschmieder; Frank Rosenbauer; Ulrich Steidl; Bronwyn M. Owens; Daniel G Tenen
Role of transcription factors C/EBPalpha and PU.1 in normal hematopoiesis and leukemia.
International journal of hematology 2005;81(5):368-77.
2005: Ulrich Steidl; Thomas Schroeder; Christian Steidl; Guido Kobbe; Thorsten Graef; Simone Bork; Sabrina Pechtel; Slawomir Kliszewski; Andrea Kuendgen; Ulrich-Peter Rohr; Roland Fenk; Michael Schroeder; Detlef Haase; Rainer Haas; Ralf Kronenwett
Distinct gene expression pattern of malignant hematopoietic stem and progenitor cells in polycythemia vera.
Annals of the New York Academy of Sciences 2005;1044():94-108.
2005: Frank Neumann; Thorsten Graef; Christoph Tapprich; Matthias Vaupel; Ulrich Steidl; Ulrich Germing; Roland Fenk; A Hinke; Rainer Haas; Guido Kobbe
Cyclosporine A and mycophenolate mofetil vs cyclosporine A and methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings.
Bone marrow transplantation 2005;35(11):1089-93.
2005: Frank Neumann; N Teutsch; Slawomir Kliszewski; Simone Bork; Ulrich Steidl; Benedikt Brors; N Schimkus; N Roes; Ulrich Germing; Barbara Hildebrandt; Brigitte Royer-Pokora; R Eils; Norbert Gattermann; Rainer Haas; Ralf Kronenwett
Gene expression profiling of Philadelphia chromosome (Ph)-negative CD34+ hematopoietic stem and progenitor cells of patients with Ph-positive CML in major molecular remission during therapy with imatinib.
Leukemia 2005;19(3):458-60.
2005: Thorsten Graef; Ulrich Steidl; Wolfgang Nedbal; Ulrich-Peter Rohr; Roland Fenk; Rainer Haas; Ralf Kronenwett
Use of RNA interference to inhibit integrin subunit alphaV-mediated angiogenesis.
Angiogenesis 2005;8(4):361-72.
2005: Ulrich-Peter Rohr; Nina Rehfeld; Helene Geddert; Lucy Pflugfelder; Ingmar Bruns; Judith Neukirch; Astrid Rohrbeck; Hans Juergen Grote; Ulrich Steidl; Roland Fenk; Bertram Opalka; Helmut E Gabbert; Ralf Kronenwett; Rainer Haas
Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):180-5.
2005: Ulrich Steidl; Roland Fenk; Ingmar Bruns; Frank Neumann; Mustafa Kondakci; B Hoyer; Thorsten Graef; Ulrich-Peter Rohr; Simone Bork; Ralf Kronenwett; Rainer Haas; Guido Kobbe
Successful transplantation of peripheral blood stem cells mobilized by chemotherapy and a single dose of pegylated G-CSF in patients with multiple myeloma.
Bone marrow transplantation 2005;35(1):33-6.
2005: Roland Fenk; B Hoyer; Ulrich Steidl; Mustafa Kondakci; Thorsten Graef; R Heuk; Leilani Ruf; Corinna Strupp; Frank Neumann; Ulrich-Peter Rohr; Barbara Hildebrandt; Rainer Haas; Guido Kobbe
Single-agent thalidomide for treatment of first relapse following high-dose chemotherapy in patients with multiple myeloma.
Leukemia 2005;19(1):156-9.
2004: Ulrich-Peter Rohr; Nina Rehfeld; Lucy Pflugfelder; Helene Geddert; Wolfram Müller; Ulrich Steidl; Roland Fenk; Thorsten Graef; Matthias Schott; Klaus-Peter Thiele; Helmut E Gabbert; Ulrich Germing; Ralf Kronenwett; Rainer Haas
Expression of the tyrosine kinase c-kit is an independent prognostic factor in patients with small cell lung cancer.
International journal of cancer. Journal international du cancer 2004;111(2):259-63.
2004: Ulrich Steidl; Simone Bork; Sebastian Schaub; Oliver Selbach; Janette Seres; Manuel Aivado; Thomas Schroeder; Ulrich-Peter Rohr; Roland Fenk; Slawomir Kliszewski; Christian Maercker; Peter Neubert; Stefan R Bornstein; Helmut L Haas; Guido Kobbe; Daniel G Tenen; Rainer Haas; Ralf Kronenwett
Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators.
Blood 2004;104(1):81-8.
2004: Roland Fenk; Muharrem Ak; Guido Kobbe; Ulrich Steidl; Carolin Arnold; Mark Korthals; Ali Hünerlitürkoglu; Ulrich-Peter Rohr; Slawomir Kliszewski; Alf Bernhardt; Rainer Haas; Ralf Kronenwett
Levels of minimal residual disease detected by quantitative molecular monitoring herald relapse in patients with multiple myeloma.
Haematologica 2004;89(5):557-66.
2004: Guido Kobbe; Roland Fenk; Frank Neumann; Alf Bernhardt; Ulrich Steidl; Mustafa Kondakci; Thorsten Graef; Manuel Aivado; Matthias Vaupel; A-N Huenerlituerkoglu; Ralf Kronenwett; Hildegard Pape; B Hildebrand; Ulrich Germing; Rainer Haas
Transplantation of allogeneic CD34+-selected cells followed by early T-cell add-backs: favorable results in acute and chronic myeloid leukemia.
Cytotherapy 2004;6(6):533-42.
2003: Ulrich-Peter Rohr; Marc-Andre Wulf; Susanne Stahn; Florian Heyd; Ulrich Steidl; Roland Fenk; Bertram Opalka; Gerald Pitschke; Hans-Bernd Prisack; Hans Bojar; Rainer Haas; Ralf Kronenwett
Non-small lung cancer cells are prime targets for p53 gene transfer mediated by a recombinant adeno-associated virus type-2 vector.
Cancer gene therapy 2003;10(12):898-906.
2003: Ulrich Steidl; Ralf Kronenwett; Rainer Haas
Differential gene expression underlying the functional distinctions of primary human CD34+ hematopoietic stem and progenitor cells from peripheral blood and bone marrow.
Annals of the New York Academy of Sciences 2003;996():89-100.
2003: Ulrich Steidl; Ralf Kronenwett; Simona Martin; Rainer Haas
Molecular biology of hematopoietic stem cells.
Vitamins and hormones 2003;66():1-28.
2002: Ulrich-Peter Rohr; Marc-Andre Wulf; Susanne Stahn; Ulrich Steidl; Rainer Haas; Ralf Kronenwett
Fast and reliable titration of recombinant adeno-associated virus type-2 using quantitative real-time PCR.
Journal of virological methods 2002;106(1):81-8.
2002: Ralf Kronenwett; Thorsten Graef; Wolfgang Nedbal; Markus Weber; Ulrich Steidl; Ulrich-Peter Rohr; Thomas Möhler; Rainer Haas
Inhibition of angiogenesis in vitro by alphav integrin-directed antisense oligonucleotides.
Cancer gene therapy 2002;9(7):587-96.
2002: Ulrich Steidl; Ralf Kronenwett; Ulrich-Peter Rohr; Roland Fenk; Slawomir Kliszewski; Christian Maercker; Peter Neubert; Manuel Aivado; Judith Koch; Olga Modlich; Hans Bojar; Norbert Gattermann; Rainer Haas
Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells.
Blood 2002;99(6):2037-44.
2000: Ulrich Steidl; Rainer Haas; Ralf Kronenwett
Intercellular adhesion molecular 1 on monocytes mediates adhesion as well as trans-endothelial migration and can be downregulated using antisense oligonucleotides.
Annals of hematology 2000;79(8):414-23.
1999: V Patzel; Ulrich Steidl; Ralf Kronenwett; R Haas; Georg Sczakiel
A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability.
Nucleic acids research 1999;27(22):4328-34.
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