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Denise Sheer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Forshew Tim; Tatevossian Ruth G; Lawson Andrew R J; Ma Jing; Neale Geoff; Ogunkolade Babatunji W; Jones Tania A; Aarum Johan; Dalton James; Bailey Simon; Chaplin Tracy; Carter Rowena L; Gajjar Amar; Broniscer Alberto; Young Bryan D; Ellison David W; Sheer Denise
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.
Bax Dorine A; Little Suzanne E; Gaspar Nathalie; Perryman Lara; Marshall Lynley; Viana-Pereira Marta; Jones Tania A; Williams Richard D; Grigoriadis Anita; Vassal Gilles; Workman Paul; Sheer Denise; Reis Rui M; Pearson Andrew D J; Hargrave Darren; Jones Chris
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
Ottaviani Diego; Lever Elliott; Mitter Richard; Jones Tania; Forshew Tim; Christova Rossitza; Tomazou Eleni M; Rakyan Vardhman K; Krawetz Stephen A; Platts Adrian E; Segarane Badmavady; Beck Stephan; Sheer Denise
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.

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All Publications

2009: Forshew Tim; Tatevossian Ruth G; Lawson Andrew R J; Ma Jing; Neale Geoff; Ogunkolade Babatunji W; Jones Tania A; Aarum Johan; Dalton James; Bailey Simon; Chaplin Tracy; Carter Rowena L; Gajjar Amar; Broniscer Alberto; Young Bryan D; Ellison David W; Sheer Denise
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.
The Journal of pathology 2009;218(2):172-81.
2009: Bax Dorine A; Little Suzanne E; Gaspar Nathalie; Perryman Lara; Marshall Lynley; Viana-Pereira Marta; Jones Tania A; Williams Richard D; Grigoriadis Anita; Vassal Gilles; Workman Paul; Sheer Denise; Reis Rui M; Pearson Andrew D J; Hargrave Darren; Jones Chris
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
PloS one 2009;4(4):e5209.
2008: Ottaviani Diego; Lever Elliott; Mitter Richard; Jones Tania; Forshew Tim; Christova Rossitza; Tomazou Eleni M; Rakyan Vardhman K; Krawetz Stephen A; Platts Adrian E; Segarane Badmavady; Beck Stephan; Sheer Denise
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.
Genome research 2008;18(11):1778-86.
2008: Tomazou Eleni M; Rakyan Vardhman K; Lefebvre Gregory; Andrews Robert; Ellis Peter; Jackson David K; Langford Cordelia; Francis Matthew D; Bäckdahl Liselotte; Miretti Marcos; Coggill Penny; Ottaviani Diego; Sheer Denise; Murrell Adele; Beck Stephan
Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis.
BMC medical genomics 2008;1():19.
2007: Takousis Petros; Johonnett Peter; Williamson Jill; Sasieni Peter; Warnes Gary; Forshew Tim; Azuara Veronique; Fisher Amanda; Wu Pei-Jun; Jones Tania; Vatcheva Radost; Beck Stephan; Sheer Denise
Replication timing profile reflects the distinct functional and genomic features of the MHC class II region.
Cell cycle (Georgetown, Tex.) 2007;6(19):2393-8.
2007: Christova Rossitza; Jones Tania; Wu Pei-Jun; Bolzer Andreas; Costa-Pereira Ana P; Watling Diane; Kerr Ian M; Sheer Denise
P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma.
Journal of cell science 2007;120(Pt 18):3262-70.
2007: Donev R; Newall A; Thome J; Sheer D
A role for SC35 and hnRNPA1 in the determination of amyloid precursor protein isoforms.
Molecular psychiatry 2007;12(7):681-90.
2006: Mulholland Paul J; Fiegler Heike; Mazzanti Chiara; Gorman Patricia; Sasieni Peter; Adams Joanna; Jones Tania A; Babbage Jane W; Vatcheva Radost; Ichimura Koichi; East Philip; Poullikas Chrysanthos; Collins V Peter; Carter Nigel P; Tomlinson Ian P M; Sheer Denise
Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme.
Cell cycle (Georgetown, Tex.) 2006;5(7):783-91.
2005: Enukashvily Natella; Donev Rossen; Sheer Denise; Podgornaya Olga
Satellite DNA binding and cellular localisation of RNA helicase P68.
Journal of cell science 2005;118(Pt 3):611-22.
2004: Wang Jayson; Shiels Carol; Sasieni Peter; Wu Pei Jun; Islam Suhail A; Freemont Paul S; Sheer Denise
Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions.
The Journal of cell biology 2004;164(4):515-26.
2003: Donev Rossen; Horton Roger; Beck Stephan; Doneva Teodora; Vatcheva Radost; Bowen W Richard; Sheer Denise
Recruitment of heterogeneous nuclear ribonucleoprotein A1 in vivo to the LMP/TAP region of the major histocompatibility complex.
The Journal of biological chemistry 2003;278(7):5214-26.
2002: Donev Rossen M; Doneva Teodora A; Bowen W Richard; Sheer Denise
HnRNP-A1 binds directly to double-stranded DNA in vitro within a 36 bp sequence.
Molecular and cellular biochemistry 2002;233(1-2):181-5.
2002: Williams Ruth R E; Broad Simon; Sheer Denise; Ragoussis Jiannis
Subchromosomal positioning of the epidermal differentiation complex (EDC) in keratinocyte and lymphoblast interphase nuclei.
Experimental cell research 2002;272(2):163-75.
2001: Shiels C; Islam S A; Vatcheva R; Sasieni P; Sternberg M J; Freemont P S; Sheer D
PML bodies associate specifically with the MHC gene cluster in interphase nuclei.
Journal of cell science 2001;114(Pt 20):3705-16.
2001: Volpi E V; Sheer D; Uhlmann F
Cohesion, but not too close.
Current biology : CB 2001;11(10):R378.
2001: Abdel-Rahman W M; Katsura K; Rens W; Gorman P A; Sheer D; Bicknell D; Bodmer W F; Arends M J; Wyllie A H; Edwards P A
Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2538-43.
2001: Schultz J; Jones T; Bork P; Sheer D; Blencke S; Steyrer S; Wellbrock U; Bevec D; Ullrich A; Wallasch C
Molecular characterization of a cDNA encoding functional human CLK4 kinase and localization to chromosome 5q35 [correction of 4q35].
Genomics 2001;71(3):368-70.
2001: Sirivatanauksorn V; Sirivatanauksorn Y; Gorman P A; Davidson J M; Sheer D; Moore P S; Scarpa A; Edwards P A; Lemoine N R
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
International journal of cancer. Journal international du cancer 2001;91(3):350-8.
2000: Jones T A; Flomen R H; Senger G; Nizetic D; Sheer D
The homeobox gene MEIS1 is amplified in IMR-32 and highly expressed in other neuroblastoma cell lines.
European journal of cancer (Oxford, England : 1990) 2000;36(18):2368-74.
2000: Taylor C P; Bown N P; McGuckin A G; Lunec J; Malcolm A J; Pearson A D; Sheer D
Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors in neuroblastoma. United Kingdom Children's Cancer Study Group.
British journal of cancer 2000;83(1):40-9.
2000: Woodford-Richens K; Williamson J; Bevan S; Young J; Leggett B; Frayling I; Thway Y; Hodgson S; Kim J C; Iwama T; Novelli M; Sheer D; Poulsom R; Wright N; Houlston R; Tomlinson I
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium.
Cancer research 2000;60(9):2477-82.
2000: Volpi E V; Chevret E; Jones T; Vatcheva R; Williamson J; Beck S; Campbell R D; Goldsworthy M; Powis S H; Ragoussis J; Trowsdale J; Sheer D
Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei.
Journal of cell science 2000;113 ( Pt 9)():1565-76.
2000: Wilson M J; Torkar M; Haude A; Milne S; Jones T; Sheer D; Beck S; Trowsdale J
Plasticity in the organization and sequences of human KIR/ILT gene families.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4778-83.
2000: Groet J; Ives J H; Jones T A; Danton M; Flomen R H; Sheer D; Hrascan R; Pavelic K; Nizetic D
Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment.
Genes, chromosomes & cancer 2000;27(2):153-61.
2000: Chevret E; Volpi E V; Sheer D
Mini review: form and function in the human interphase chromosome.
Cytogenetics and cell genetics 2000;90(1-2):13-21.
1999: Kashuba V I; Gizatullin R Z; Protopopov A I; Li J; Vorobieva N V; Fedorova L; Zabarovska V I; Muravenko O V; Kost-Alimova M; Domninsky D A; Kiss C; Allikmets R; Zakharyev V M; Braga E A; Sumegi J; Lerman M; Wahlestedt C; Zelenin A V; Sheer D; Winberg G; Grafodatsky A; Kisselev L L; Klein G; Zabarovsky E R
Analysis of NotI linking clones isolated from human chromosome 3 specific libraries.
Gene 1999;239(2):259-71.
1999: Lamlum H; Ilyas M; Rowan A; Clark S; Johnson V; Bell J; Frayling I; Efstathiou J; Pack K; Payne S; Roylance R; Gorman P; Sheer D; Neale K; Phillips R; Talbot I; Bodmer W; Tomlinson I
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.
Nature medicine 1999;5(9):1071-5.
1999: Roylance R; Gorman P; Harris W; Liebmann R; Barnes D; Hanby A; Sheer D
Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer.
Cancer research 1999;59(7):1433-6.
1999: Berchtold S; Jones T; Mühl-Zürbes P; Sheer D; Schuler G; Steinkasserer A
The human dendritic cell marker CD83 maps to chromosome 6p23.
Annals of human genetics 1999;63(Pt 2):181-3.
1999: Mao X; Jones T A; Tomlinson I; Rowan A J; Fedorova L I; Zelenin A V; Mao J I; Gutowski N J; Noble M; Sheer D
Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line.
British journal of cancer 1999;79(5-6):724-31.
1998: Saurin A J; Shiels C; Williamson J; Satijn D P; Otte A P; Sheer D; Freemont P S
The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain.
The Journal of cell biology 1998;142(4):887-98.
1998: Watt S M; Bühring H J; Rappold I; Chan J Y; Lee-Prudhoe J; Jones T; Zannettino A C; Simmons P J; Doyonnas R; Sheer D; Butler L H
CD164, a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21.
Blood 1998;92(3):849-66.
1998: Herberg J A; Phillips S; Beck S; Jones T; Sheer D; Wu J J; Prochazka V; Barr P J; Kiefer M C; Trowsdale J
Genomic structure and domain organisation of the human Bak gene.
Gene 1998;211(1):87-94.
1998: Herberg J A; Sgouros J; Jones T; Copeman J; Humphray S J; Sheer D; Cresswell P; Beck S; Trowsdale J
Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC.
European journal of immunology 1998;28(2):459-67.
1998: Chadwick B P; Williamson J; Sheer D; Frischauf A M
cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(2):162-4.
1998: Howe K; Williamson J; Boddy N; Sheer D; Freemont P; Solomon E
The ubiquitin-homology gene PIC1: characterization of mouse (Pic1) and human (UBL1) genes and pseudogenes.
Genomics 1998;47(1):92-100.
1998: Chadwick B P; Heath S K; Williamson J; Obermayr F; Patel L; Sheer D; Frischauf A M
The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI).
Genomics 1998;47(1):58-63.
1997: Grimwade D; Gorman P; Duprez E; Howe K; Langabeer S; Oliver F; Walker H; Culligan D; Waters J; Pomfret M; Goldstone A; Burnett A; Freemont P; Sheer D; Solomon E
Characterization of cryptic rearrangements and variant translocations in acute promyelocytic leukemia.
Blood 1997;90(12):4876-85.
1997: Thorpe K L; Gorman P; Thomas C; Sheer D; Trowsdale J; Beck S
Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.
Gene 1997;200(1-2):177-83.
1997: McCusker D; Jones T; Sheer D; Trowsdale J
Genetic relationships of the genes encoding the human proteasome beta subunits and the proteasome PA28 complex.
Genomics 1997;45(2):362-7.
1997: Fedorova L; Kost-Alimova M; Gizatullin R Z; Alimov A; Zabarovska V I; Szeles A; Protopopov A I; Vorobieva N V; Kashuba V I; Klein G; Zelenin A V; Sheer D; Zabarovsky E R
Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'-monophosphate synthetase gene to human chromosome 3.
European journal of human genetics : EJHG 1997;5(2):110-6.
1997: Flomen R H; Gorman P A; Vatcheva R; Groet J; Barisic I; Ligutic I; Sheer D; Nizetic D
Rieger syndrome locus: a new reciprocal translocation t(4;12)(q25;q15) and a deletion del(4)(q25q27) both break between markers D4S2945 and D4S193.
Journal of medical genetics 1997;34(3):191-5.
1997: Roylance R; Spurr N; Sheer D
The genetic analysis of prostate carcinoma.
Seminars in cancer biology 1997;8(1):37-44.
1997: Jones T; Sheer D; Bevec D; Kappel B; Hauber J; Steinkasserer A
The human HIV-1 Rev binding-protein hRIP/Rab (HRB) maps to chromosome 2q36.
Genomics 1997;40(1):198-9.
1997: Xu W; Liu L; Gorman P A; Sheer D; Emson P C
Assignment of the human creatine transporter type 2 (SLC6A10) to chromosome band 16p11.2 by in situ hybridization.
Cytogenetics and cell genetics 1997;76(1-2):19.
1996: Ruhrberg C; Williamson J A; Sheer D; Watt F M
Chromosomal localisation of the human envoplakin gene (EVPL) to the region of the tylosis oesophageal cancer gene (TOCG) on 17q25.
Genomics 1996;37(3):381-5.
1996: Jones T; Sheer D; Kapetanopoulos A; Hauber J; Bevec D; Steinkasserer A
The gene coding for human deoxyhypusine synthase (DHPS) maps to chromosome 19p13.11-p13.12.
Genomics 1996;35(3):635-7.
1996: Tassabehji M; Metcalfe K; Fergusson W D; Carette M J; Dore J K; Donnai D; Read A P; Pröschel C; Gutowski N J; Mao X; Sheer D
LIM-kinase deleted in Williams syndrome.
Nature genetics 1996;13(3):272-3.
1996: Williamson J A; Bosher J M; Skinner A; Sheer D; Williams T; Hurst H C
Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors.
Genomics 1996;35(1):262-4.
1996: Thomas H J; Whitelaw S C; Cottrell S E; Murday V A; Tomlinson I P; Markie D; Jones T; Bishop D T; Hodgson S V; Sheer D; Northover J M; Talbot I C; Solomon E; Bodmer W F
Genetic mapping of hereditary mixed polyposis syndrome to chromosome 6q.
American journal of human genetics 1996;58(4):770-6.
1996: Wang X C; Katso R; Butler R; Hanby A M; Poulsom R; Jones T; Sheer D; Ganesan T S
H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer.
Molecular medicine (Cambridge, Mass.) 1996;2(2):189-203.
1996: Sheer D; Squire J
Clinical applications of genetic rearrangements in cancer.
Seminars in cancer biology 1996;7(1):25-32.
1996: Han X; Papadopoulos A J; Jones T A; Sheer D; Raju K S
SR8--the establishment and characterisation of a new ovarian carcinoma cell line and xenograft model.
European journal of cancer (Oxford, England : 1990) 1996;32A(1):160-7.
1996: Mao X; Jones T A; Williamson J; Gutowski N J; Pröschel C; Noble M; Sheer D
Assignment of the human and mouse LIM-kinase genes (LIMK1; Limk1) to chromosome bands 7q11.23 and 5G1, respectively, by in situ hybridization.
Cytogenetics and cell genetics 1996;74(3):190-1.
1995: Dunne J; Hanby A M; Poulsom R; Jones T A; Sheer D; Chin W G; Da S M; Zhao Q; Beverley P C; Owen M J
Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule.
Genomics 1995;30(2):207-23.
1995: Waxman J; Sheer D
Is prostate cancer worth diagnosing?
Lancet 1995;346(8984):1177-8.
1995: Shipley J; Williams S; O'Byrne A; Kearney L; Jones T; Young B; Dyer M; Catovsky D; Sheer D; Gusterson B
Characterization of a t(10;11)(p13-14;q14-21) in the monoblastic cell line U937.
Genes, chromosomes & cancer 1995;13(2):138-42.
1995: Gill S; McManus A P; Crew A J; Benjamin H; Sheer D; Gusterson B A; Pinkerton C R; Patel K; Cooper C S; Shipley J M
Fusion of the EWS gene to a DNA segment from 9q22-31 in a human myxoid chondrosarcoma.
Genes, chromosomes & cancer 1995;12(4):307-10.
1995: Steinkasserer A; Jones T; Sheer D; Koettnitz K; Hauber J; Bevec D
The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.
Genomics 1995;25(3):749-52.
1995: Zarn J A; Jackson D G; Bell M V; Jones T; Weber E; Sheer D; Waibel R; Stahel R A
The small cell lung cancer antigen cluster-4 and the leukocyte antigen CD24 are allelic isoforms of the same gene (CD24) on chromosome band 6q21.
Cytogenetics and cell genetics 1995;70(1-2):119-25.
1994: Shipley J; Sheer D; Dalton S; Treisman R; Patel K
Mapping of the human SAP1 (SRF accessory protein 1) gene and SAP2, a gene encoding a related protein, to chromosomal bands 1q32 and 12q23, respectively.
Genomics 1994;23(3):710-1.
1994: Belich M P; Glynne R J; Senger G; Sheer D; Trowsdale J
Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins.
Current biology : CB 1994;4(9):769-76.
1994: Delattre O; Zucman J; Melot T; Garau X S; Zucker J M; Lenoir G M; Ambros P F; Sheer D; Turc-Carel C; Triche T J
The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts.
The New England journal of medicine 1994;331(5):294-9.
1994: Senger G; Jones T A; Fidlerová H; Sanséau P; Trowsdale J; Duff M; Sheer D
Released chromatin: linearized DNA for high resolution fluorescence in situ hybridization.
Human molecular genetics 1994;3(8):1275-80.
1994: Sanséau P; Jackson A; Alderton R P; Beck S; Senger G; Sheer D; Kelly A; Trowsdale J
Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(8):490-6.
1994: Emslie E A; Jones T A; Sheer D; Keyse S M
The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34.
Human genetics 1994;93(5):513-6.
1994: Samec S; Jones T A; Corlet J; Scherly D; Sheer D; Wood R D; Clarkson S G
The human gene for xeroderma pigmentosum complementation group G (XPG) maps to 13q33 by fluorescence in situ hybridization.
Genomics 1994;21(1):283-5.
1994: Sanséau P; Jackson A; Senger G; Kelly A; Francis F; Sheer D; Trowsdale J
Cloning of the region between HLA-DMB and LMP2 in the human major histocompatibility complex.
Human immunology 1994;40(1):1-7.
1994: Xu W; Charles I G; Moncada S; Gorman P; Sheer D; Liu L; Emson P
Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively.
Genomics 1994;21(2):419-22.
1994: Borrow J; Shipley J; Howe K; Kiely F; Goddard A; Sheer D; Srivastava A; Antony A C; Fioretos T; Mitelman F
Molecular analysis of simple variant translocations in acute promyelocytic leukemia.
Genes, chromosomes & cancer 1994;9(4):234-43.
1994: Taylor C P; McGuckin A G; Bown N P; Reid M M; Malcolm A J; Pearson A D; Sheer D
Rapid detection of prognostic genetic factors in neuroblastoma using fluorescence in situ hybridisation on tumour imprints and bone marrow smears. United Kingdom Children's Cancer Study Group.
British journal of cancer 1994;69(3):445-51.
1994: Ben-Arie N; Lancet D; Taylor C; Khen M; Walker N; Ledbetter D H; Carrozzo R; Patel K; Sheer D; Lehrach H
Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.
Human molecular genetics 1994;3(2):229-35.
1994: Fidlerová H; Senger G; Kost M; Sanseau P; Sheer D
Two simple procedures for releasing chromatin from routinely fixed cells for fluorescence in situ hybridization.
Cytogenetics and cell genetics 1994;65(3):203-5.
1993: Zucman J; Melot T; Desmaze C; Ghysdael J; Plougastel B; Peter M; Zucker J M; Triche T J; Sheer D; Turc-Carel C
Combinatorial generation of variable fusion proteins in the Ewing family of tumours.
The EMBO journal 1993;12(12):4481-7.
1993: Ward J R; Cottrell S; Thomas H J; Jones T A; Howe C M; Hampton G M; Deaven L; Sheer D; Bodmer W F; Solomon E
A long-range restriction map of human chromosome 5q21-q23.
Genomics 1993;17(1):15-24.
1993: Patel K; Sheer D; Hampton G M
"Junction trapping". A simple PCR-based method for the isolation of YAC-insert termini.
Genetic analysis, techniques and applications 1993;10(2):42-8.
1993: Markie D; Ragoussis J; Senger G; Rowan A; Sansom D; Trowsdale J; Sheer D; Bodmer W F
New vector for transfer of yeast artificial chromosomes to mammalian cells.
Somatic cell and molecular genetics 1993;19(2):161-9.
1993: Yon J; Jones T; Garson K; Sheer D; Fried M
The organization and conservation of the human Surfeit gene cluster and its localization telomeric to the c-abl and can proto-oncogenes at chromosome band 9q34.1.
Human molecular genetics 1993;2(3):237-40.
1993: Taylor C; Patel K; Jones T; Kiely F; De Stavola B L; Sheer D
Diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumour based on the detection of t(11;22) using fluorescence in situ hybridisation.
British journal of cancer 1993;67(1):128-33.
1993: Senger G; Ragoussis J; Trowsdale J; Sheer D
Fine mapping of the human MHC class II region within chromosome band 6p21 and evaluation of probe ordering using interphase fluorescence in situ hybridization.
Cytogenetics and cell genetics 1993;64(1):49-53.
1993: Barnett P S; Jones T A; McGregor A M; Banga J P; Sheer D
Regional sublocalization of the human thyroid peroxidase gene (TPO) by tritium and fluorescence in situ hybridization to chromosome 2p25-->p24.
Cytogenetics and cell genetics 1993;62(4):188-9.
1993: Shipley J M; Jones T A; Patel K; Kiely F M; De Stavola B L; Sheer D
Ordering of probes surrounding the Ewing's sarcoma breakpoint on chromosome 22 using fluorescent in situ hybridization to interphase nuclei.
Cytogenetics and cell genetics 1993;64(3-4):233-9.
1993: Jones T A; Barker H M; da Cruz e Silva E F; Mayer-Jaekel R E; Hemmings B A; Spurr N K; Sheer D; Cohen P T
Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively.
Cytogenetics and cell genetics 1993;63(1):35-41.
1993: Xu W; Gorman P; Sheer D; Bates G; Kishimoto J; Lizhi L; Emson P
Regional localization of the gene coding for human brain nitric oxide synthase (NOS1) to 12q24.2-->24.31 by fluorescent in situ hybridization.
Cytogenetics and cell genetics 1993;64(1):62-3.
1992: Cole C G; Patel K; Shipley J; Sheer D; Bobrow M; Bentley D R; Dunham I
Identification of region-specific yeast artificial chromosomes using pools of Alu element-mediated polymerase chain reaction probes labeled via linear amplification.
Genomics 1992;14(4):931-8.
1992: Ragoussis J; Senger G; Mockridge I; Sanseau P; Ruddy S; Dudley K; Sheer D; Trowsdale J
A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11.
Genomics 1992;14(3):673-9.
1992: Jenkins J R; Ayton P; Jones T; Davies S L; Simmons D L; Harris A L; Sheer D; Hickson I D
Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24.
Nucleic acids research 1992;20(21):5587-92.
1992: Markie D; Jones T A; Sheer D; Bodmer W F
A somatic cell hybrid panel for regional mapping of human chromosome 18.
Genomics 1992;14(2):431-6.
1992: Calabrese G; Palka G; Westbrook C A; Sheer D
Complex translocation involving Ph chromosome in a patient with typical chronic myelogenous leukemia.
Cancer genetics and cytogenetics 1992;63(1):52-5.
1992: Mattson A J; Sheer D E; Fletcher J M
Electrophysiological evidence of lateralized disturbances in children with learning disabilities.
Journal of clinical and experimental neuropsychology 1992;14(5):707-16.
1992: Hampton G M; Ward J R; Cottrell S; Howe K; Thomas H J; Ballhausen W G; Jones T; Sheer D; Solomon E; Frischauf A M
Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8249-53.
1992: Lennard A; Gorman P; Carrier M; Griffiths S; Scotney H; Sheer D; Solari R
Cloning and chromosome mapping of the human interleukin-1 receptor antagonist gene.
Cytokine 1992;4(2):83-9.
1991: Hämäläinen E R; Jones T A; Sheer D; Taskinen K; Pihlajaniemi T; Kivirikko K I
Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2.
Genomics 1991;11(3):508-16.
1991: Heard E; Williams S V; Sheer D; Fried M
Gene amplification accompanied by the loss of a chromosome containing the native allele and the appearance of the amplified DNA at a new chromosomal location.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):8242-6.
1991: Patel K; Cox R; Shipley J; Kiely F; Frazer K; Cox D R; Lehrach H; Sheer D
A novel and rapid method for isolating sequences adjacent to rare cutting sites and their use in physical mapping.
Nucleic acids research 1991;19(16):4371-5.
1991: Ragoussis J; Jones T A; Sheer D; Shrimpton A E; Goodfellow P N; Trowsdale J; Ziegler A
Isolation of probes specific to human chromosomal region 6p21 from immunoselected irradiation-fusion gene transfer hybrids.
Genomics 1991;10(3):598-607.
1991: Dietrich A; Kioschis P; Monaco A P; Gross B; Korn B; Williams S V; Sheer D; Heitz D; Oberle I; Toniolo D
Molecular cloning and analysis of the fragile X region in man.
Nucleic acids research 1991;19(10):2567-72.
1991: Gorman P A; Malone M; Pritchard J; Sheer D
Cytogenetic analysis of primitive neuroectodermal tumors. Absence of the t(11;22) in two of three cases and a review of the literature.
Cancer genetics and cytogenetics 1991;51(1):13-22.
1991: Pajunen L; Jones T A; Goddard A; Sheer D; Solomon E; Pihlajaniemi T; Kivirikko K I
Regional assignment of the human gene coding for a multifunctional polypeptide (P4HB) acting as the beta-subunit of prolyl 4-hydroxylase and the enzyme protein disulfide isomerase to 17q25.
Cytogenetics and cell genetics 1991;56(3-4):165-8.
1990: Wynford-Thomas D; Bond J A; Wyllie F S; Burns J S; Williams E D; Jones T; Sheer D; Lemoine N R
Conditional immortalization of human thyroid epithelial cells: a tool for analysis of oncogene action.
Molecular and cellular biology 1990;10(10):5365-77.
1990: Borrow J; Goddard A D; Sheer D; Solomon E
Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17.
Science (New York, N.Y.) 1990;249(4976):1577-80.
1990: Gorman P A; Malone M; Pritchard J; Sheer D
Deletion of part of the short arm of chromosome 17 in a congenital fibrosarcoma.
Cancer genetics and cytogenetics 1990;48(2):193-8.
1990: Myers J C; Jones T A; Pohjolainen E R; Kadri A S; Goddard A D; Sheer D; Solomon E; Pihlajaniemi T
Molecular cloning of alpha 5(IV) collagen and assignment of the gene to the region of the X chromosome containing the Alport syndrome locus.
American journal of human genetics 1990;46(6):1024-33.
1990: Barker H M; Jones T A; da Cruz e Silva E F; Spurr N K; Sheer D; Cohen P T
Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.
Genomics 1990;7(2):159-66.
1990: Sheer D; Gorman P A; Whelan R; Hill B T
Cytogenetic analysis of a cell line established from a Krukenberg tumor.
Cancer genetics and cytogenetics 1990;46(1):71-4.
1990: Edwards Y; Williams S; West L; Lipowicz S; Sheer D; Attwood J; Spurr N; Sarkar R; Saha N; Povey S
The polymorphic human DNA sequence D8S8 assigned to 8q13-21.1, close to the carbonic anhydrase gene cluster, by isotopic and nonisotopic in situ hybridization and by linkage analysis.
Annals of human genetics 1990;54(Pt 2):131-9.
1990: Lord D K; Cross N C; Bevilacqua M A; Rider S H; Gorman P A; Groves A V; Moss D W; Sheer D; Cox T M
Type 5 acid phosphatase. Sequence, expression and chromosomal localization of a differentiation-associated protein of the human macrophage.
European journal of biochemistry / FEBS 1990;189(2):287-93.
1990: Jones T A; da Cruz e Silva E F; Spurr N K; Sheer D; Cohen P T
Localisation of the gene encoding the catalytic gamma subunit of phosphorylase kinase to human chromosome bands 7p12-q21.
Biochimica et biophysica acta 1990;1048(1):24-9.
1989: Lemoine N R; Mayall E S; Jones T; Sheer D; McDermid S; Kendall-Taylor P; Wynford-Thomas D
Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection.
British journal of cancer 1989;60(6):897-903.
1989: Varesco L; Thomas H J; Cottrell S; Murday V; Fennell S J; Williams S; Searle S; Sheer D; Bodmer W F; Frischauf A M
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):10118-22.
1989: Pajunen L; Jones T A; Helaakoski T; Pihlajaniemi T; Solomon E; Sheer D; Kivirikko K I
Assignment of the gene coding for the alpha-subunit of prolyl 4-hydroxylase to human chromosome region 10q21.3-23.1.
American journal of human genetics 1989;45(6):829-34.
1989: Davies A A; Moss S E; Crompton M R; Jones T A; Spurr N K; Sheer D; Kozak C; Crumpton M J
The gene coding for the p68 calcium-binding protein is localised to bands q32-q34 of human chromosome 5, and to mouse chromosome 11.
Human genetics 1989;82(3):234-8.
1989: Yon J; Palmer R W; Sheer D; Fried M
Localization of the Surfeit gene cluster containing the ribosomal protein gene L7a to chromosome bands 9q33-34.
Annals of human genetics 1989;53(Pt 2):149-55.
1989: Moore G; Hedge P J; Rider S H; Xu W; Hing S; Palmer R; Sheer D; Solomon E
Multiple tandem 18-kb sequences clustered in the region of the acute promyelocytic leukemia breakpoint on chromosome 17.
Genomics 1989;4(2):152-61.
1989: Goodfellow P J; Nevanlinna H A; Gorman P; Sheer D; Lam G; Goodfellow P N
Assignment of the gene encoding the beta-subunit of the human fibronectin receptor (beta-FNR) to chromosome 10p11.2.
Annals of human genetics 1989;53(Pt 1):15-22.
1989: Shipley J; Sheer D
Deletion of c-ets1 and T3 gamma loci from the 11q- chromosome in the human monoblastic cell line U937.
Leukemia research 1989;13(6):445-50.
1988: Xu W M; Gorman P A; Rider S H; Hedge P J; Moore G; Prichard C; Sheer D; Solomon E
Construction of a genetic map of human chromosome 17 by use of chromosome-mediated gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8563-7.
1988: Whelan R; Gibby E; Sheer D; Povey S; Hill B T
Characterization of a continuous cell line in culture established from a Krukenberg tumour of the ovary arising from a primary gastric adenocarcinoma.
European journal of cancer & clinical oncology 1988;24(9):1397-408.
1987: Rider S H; Gorman P A; Shipley J M; Moore G; Vennstrom B; Solomon E; Sheer D
Localization of the oncogene c-erbA2 to human chromosome 3.
Annals of human genetics 1987;51(Pt 2):153-60.
1987: Martin D; Tucker D F; Gorman P; Sheer D; Spurr N K; Trowsdale J
The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37.
Annals of human genetics 1987;51(Pt 2):145-52.
1987: Eridani S; Gorman P; Sheer D; Duncombe A S; Glass U H; Shivji M K
Monosomy 7 and Ph-positive acute lymphoblastic leukaemia: cytogenetic and molecular aspects.
Leukemia research 1987;11(11):965-9.

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