FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kay-Uwe Wagner

Research Profile

Living Beings

Anatomy

Chemicals & Drugs

Concepts & Ideas

Lactation

Physiology

Disorders

Mammary Neoplasms, Experimental

Co-author Network

Publications

TOP 3
Hong Xin; Chunyan Zhang; Wang Zhang; Jiehui Deng; Stephen Forman; Richard Jove; Heehyoung Lee; Yong Liu; Rongze Lu; Shudan Shen; Kay-Uwe Wagner; Hua Yu
G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells.
Bryan D Bell; Kristen Dang; Lothar Hennighausen; Masayuki Kitajima; Ryan P Larson; Boris Reizis; Kazuhito Sakamoto; Thomas A Stoklasek; Kay-Uwe Wagner; Steven F Ziegler
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Wan-chi Lin; Chengbao Liu; John P Morris; Rene Opavsky; Nirakar Rajbhandari; Hallgeir Rui; Kazuhito Sakamoto; Aleata A Triplett; Surinder K Batra; Jonathan R Brody; Dominick J DiMaio; Dean W Felsher; Matthias Hebrok; Michael A Hollingsworth; Agnieszka K Witkiewicz; Qian Zhang; Kay-Uwe Wagner
Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kay-Uwe Wagner (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Hong Xin; Chunyan Zhang; Wang Zhang; Jiehui Deng; Stephen Forman; Richard Jove; Heehyoung Lee; Yong Liu; Rongze Lu; Shudan Shen; Kay-Uwe Wagner; Hua Yu
G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells.
The Journal of biological chemistry 2013;288(19):13842-9.
2013: Bryan D Bell; Kristen Dang; Lothar Hennighausen; Masayuki Kitajima; Ryan P Larson; Boris Reizis; Kazuhito Sakamoto; Thomas A Stoklasek; Kay-Uwe Wagner; Steven F Ziegler
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Nature immunology 2013;14(4):364-71.
2013: Wan-chi Lin; Chengbao Liu; John P Morris; Rene Opavsky; Nirakar Rajbhandari; Hallgeir Rui; Kazuhito Sakamoto; Aleata A Triplett; Surinder K Batra; Jonathan R Brody; Dominick J DiMaio; Dean W Felsher; Matthias Hebrok; Michael A Hollingsworth; Agnieszka K Witkiewicz; Qian Zhang; Kay-Uwe Wagner
Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Cancer research 2013;73(6):1821-30.
2013: Kay-Uwe Wagner; Brian W Booth; Corinne A Boulanger; Gilbert H Smith
Multipotent PI-MECs are the true targets of MMTV-neu tumorigenesis.
Oncogene 2013;32(10):1338.
2013: Lucia Kubovcakova; Pontus Lundberg; Masato Murakami; Thomas Radimerski; Vincent Romanet; Rita Andraos; Stephan Dirnhofer; Jean Grisouard; Hui Hao-Shen; Kay-Uwe Wagner; Radek C Skoda
Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model.
Blood 2013;121(7):1188-99.
2013: Wan-chi Lin; Jeffrey W Schmidt; Aleata A Triplett; Bradley A Creamer; Kay-Uwe Wagner
Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.
PloS one 2013;8(4):e60902.
2013: Sung Ok Park; William B Slayton; Kay-Uwe Wagner; Heather L Wamsley; Kyungmi Bae; Se-Woon Choe; Zhongbo Hu; Xiaomiao Li; S Paul Oh; Peter P Sayeski
Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.
PloS one 2013;8(3):e59675.
2012: María Pilar Sánchez-Bailón; Kay-Uwe Wagner; Agnese Molinari; Beatriz Morte; Annarica Calcabrini; Daniel Gómez-Domínguez; Gonzalo Gómez-López; Esther Martín-Forero; Jorge Martín-Pérez
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells.
Cellular signalling 2012;24(6):1276-86.
2012: Sally Yu Shi; Christine Tang; Kay-Uwe Wagner; Khosrow Adeli; Richard P Bazinet; Erica P Cai; Diana Choi; Mark J Dekker; Anthony F Domenichiello; Robin E Duncan; Adria Giacca; Kathryn E Hopperton; Shun-Yan Lu; Cynthia T Luk; Rubén García Martin; Mark Naples; Stephanie A Schroer; Minna Woo
Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance.
The Journal of biological chemistry 2012;287(13):10277-88.
2012: Oliver Hantschel; Ines Kaupe; Eva Eckelhart; Florian Grebien; Giulio Superti-Furga; Kay-Uwe Wagner; Wolfgang Warsch; Veronika Sexl
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia.
Nature chemical biology 2012;8(3):285-93.
2012: Satyanarayana Rachagani; Parthasarathy Seshacharyulu; María P Torres; Kay-Uwe Wagner; Michael Baine; Parama Dey; Dhanya Haridas; Maneesh Jain; Sonny L Johansson; Sukhwinder Kaur; Sushil Kumar; Muzafar A Macha; Moorthy P Ponnusamy; Surinder K Batra
Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy.
Journal of hematology & oncology 2012;5():68.
2012: Kazuhito Sakamoto; Jeffrey W Schmidt; Kay-Uwe Wagner
Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary gland.
PloS one 2012;7(8):e43778.
2012: Chantey R Morris; Keon Bong Oh; Marissa J Stanton; Karoline C Manthey; Kay-Uwe Wagner
A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death.
PloS one 2012;7(3):e34308.
2011: Christine Schneckenleithner; Dagmar Stoiber; Kay-Uwe Wagner; Zsuzsanna Bago-Horvath; Thomas Decker; Helmut Dolznig; Dontscho Kerjaschki; Thomas Kolbe; Karoline Kollmann; Mathias Müller; Nina Neugebauer; Veronika Sexl
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
Oncotarget 2011;2(12):1043-54.
2011: Kristina M Mueller; J Andrew Pospisilik; Michaela Schlederer; Guenther Schuetz; Veronika Sexl; Luigi Terracciano; Kay-Uwe Wagner; Rudolf Zechner; Leander Blaas; Emilio Casanova; Gerda Egger; David Engblom; Harald Esterbauer; Katrin Friedbichler; Guenter Haemmerle; Susanne Haindl; Peter Hasselblatt; Markus H Heim; Lukas Kenner; Jan-Wilhelm Kornfeld; Andrey V Kozlov; Dagmar Kratky; Richard Moriggl
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Hepatology (Baltimore, Md.) 2011;54(4):1398-409.
2011: Sarah M Nordstrom; Brandon C Sos; Jennifer L Tran; Kay-Uwe Wagner; Ethan J Weiss
Liver-derived IGF-I contributes to GH-dependent increases in lean mass and bone mineral density in mice with comparable levels of circulating GH.
Molecular endocrinology (Baltimore, Md.) 2011;25(7):1223-30.
2011: Annet Kirabo; S Paul Oh; Jennifer M Sasser; Chris Baylis; Arturo J Cardounel; Maria B Grant; Yagna P R Jarajapu; Hideko Kasahara; Patrick N Kearns; Kay-Uwe Wagner; Peter P Sayeski
Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species.
Cardiovascular research 2011;91(1):171-9.
2011: Annet Kirabo; S Paul Oh; Hideko Kasahara; Kay-Uwe Wagner; Peter P Sayeski
Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice.
Journal of molecular and cellular cardiology 2011;50(6):1026-34.
2011: Brandon C Sos; Charles Harris; Sarah M Nordstrom; Jennifer L Tran; Mercedesz Balázs; Patrick Caplazi; Maria Febbraio; Milana A B Applegate; Kay-Uwe Wagner; Ethan J Weiss
Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.
The Journal of clinical investigation 2011;121(4):1412-23.
2011: Sheng Wu; Sara A DiVall; Gloria E Hoffman; Wei Wei Le; Kay-Uwe Wagner; Andrew Wolfe
Jak2 is necessary for neuroendocrine control of female reproduction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(1):184-92.
2011: Kay-Uwe Wagner; Jeffrey W Schmidt
The two faces of Janus kinases and their respective STATs in mammary gland development and cancer.
Journal of carcinogenesis 2011;10():32.
2011: Simanta Pathak; Long Trinh; Kay-Uwe Wagner; James Eudy; Shantaram S Joshi; Shibin Ma; Runqing Lu
IRF4 is a suppressor of c-Myc induced B cell leukemia.
PloS one 2011;6(7):e22628.
2011: Edmund B Rucker; Amber N Hale; David C Durtschi; Kazuhito Sakamoto; Kay-Uwe Wagner
Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein bax.
Genesis (New York, N.Y. : 2000) 2011;49(1):24-35.
2010: Diana Choi; Stephanie A Schroer; Shun Yan Lu; Linyuan Wang; Xiaohong Wu; Yunfeng Liu; Yi Zhang; Herbert Y Gaisano; Kay-Uwe Wagner; Hong Wu; Ravi Retnakaran; Minna Woo
Erythropoietin protects against diabetes through direct effects on pancreatic beta cells.
The Journal of experimental medicine 2010;207(13):2831-42.
2010: Yrina Rochman; Mohit Kashyap; Gertraud W Robinson; Kazuhito Sakamoto; Julio Gomez-Rodriguez; Kay-Uwe Wagner; Warren J Leonard
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(45):19455-60.
2010: K Sakamoto; Aleata A Triplett; L A Schuler; Kay-Uwe Wagner
Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer.
Oncogene 2010;29(39):5359-69.
2010: Chun Tu; Cesar F Ortega-Cava; Paul Winograd; Marissa Jo Stanton; Alagarsamy Lakku Reddi; Ingrid Dodge; Ranjana Arya; Manjari Dimri; Robert J Clubb; Mayumi Naramura; Kay-Uwe Wagner; Vimla Band; Hamid Band
Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(37):16107-12.
2010: Bradley A Creamer; Kazuhito Sakamoto; Jeffrey W Schmidt; Aleata A Triplett; Richard Moriggl; Kay-Uwe Wagner
Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
Molecular and cellular biology 2010;30(12):2957-70.
2010: Qian Zhang; Aleata A Triplett; Don W Harms; Wan-Chi Lin; Bradley A Creamer; Angie Rizzino; Kay-Uwe Wagner
Temporally and spatially controlled expression of transgenes in embryonic and adult tissues.
Transgenic research 2010;19(3):499-509.
2009: Kazuhito Sakamoto; Wan-chi Lin; Aleata A Triplett; Kay-Uwe Wagner
Targeting janus kinase 2 in Her2/neu-expressing mammary cancer: Implications for cancer prevention and therapy.
Cancer research 2009;69(16):6642-50.
2009: Bradley A Creamer; Aleata A Triplett; Kay-Uwe Wagner
Longitudinal analysis of mammogenesis using a novel tetracycline-inducible mouse model and in vivo imaging.
Genesis (New York, N.Y. : 2000) 2009;47(4):234-45.
2008: Aleata A Triplett; Cristina Montagna; Kay-Uwe Wagner
A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis.
Neoplasia (New York, N.Y.) 2008;10(12):1325-34.
2008: Brian Bierie; Daniel G Stover; Ty W Abel; Anna Chytil; Agnieszka E Gorska; Mary E Aakre; Elizabeth Forrester; Li Yang; Kay-Uwe Wagner; Harold L Moses
Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment.
Cancer research 2008;68(6):1809-19.
2008: Kay-Uwe Wagner; Hallgeir Rui
Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.
Journal of mammary gland biology and neoplasia 2008;13(1):93-103.
2007: J Pecha; D Ankrapp; C Jiang; W Tang; I Hoshino; K Bruck; Kay-Uwe Wagner; Hua Xiao
Deletion of Tip30 leads to rapid immortalization of murine mammary epithelial cells and ductal hyperplasia in the mammary gland.
Oncogene 2007;26(53):7423-31.
2007: Yuxin Feng; David Manka; Kay-Uwe Wagner; Sohaib A Khan
Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(37):14718-23.
2007: Lynn M Neilson; Jianquong Zhu; Jianwu Xie; Maria Grazia Malabarba; Kazuhito Sakamoto; Kay-Uwe Wagner; Robert A Kirken; Hallgeir Rui
Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.
Molecular endocrinology (Baltimore, Md.) 2007;21(9):2218-32.
2007: Keon Bong Oh; M J Stanton; W W West; G L Todd; Kay-Uwe Wagner
Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation.
Oncogene 2007;26(40):5950-9.
2007: Kazuhito Sakamoto; Bradley A Creamer; Aleata A Triplett; Kay-Uwe Wagner
The Janus kinase 2 is required for expression and nuclear accumulation of cyclin D1 in proliferating mammary epithelial cells.
Molecular endocrinology (Baltimore, Md.) 2007;21(8):1877-92.
2007: Laurice A Matulka; Aleata A Triplett; Kay-Uwe Wagner
Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells.
Developmental biology 2007;303(1):29-44.
2006: Aimee V Loladze; Malinda A Stull; Anne M Rowzee; Jean Demarco; James H Lantry; Clifford J Rosen; Derek LeRoith; Kay-Uwe Wagner; Lothar Hennighausen; Teresa L Wood
Epithelial-specific and stage-specific functions of insulin-like growth factor-I during postnatal mammary development.
Endocrinology 2006;147(11):5412-23.
2006: Fransiscus Utama; Matthew LeBaron; Lynn M Neilson; Ahmed S Sultan; A F Parlow; Kay-Uwe Wagner; Hallgeir Rui
Human prolactin receptors are insensitive to mouse prolactin: implications for xenotransplant modeling of human breast cancer in mice.
The Journal of endocrinology 2006;188(3):589-601.
2005: Aleata A Triplett; Kazuhito Sakamoto; Laurice A Matulka; Liya Shen; Gilbert H Smith; Kay-Uwe Wagner
Expression of the whey acidic protein (Wap) is necessary for adequate nourishment of the offspring but not functional differentiation of mammary epithelial cells.
Genesis (New York, N.Y. : 2000) 2005;43(1):1-11.
2005: Eleanor Y M Sum; Mark Shackleton; Kyungmin Hahm; Richard M Thomas; Lorraine A O'Reilly; Kay-Uwe Wagner; Geoffrey J Lindeman; Jane E Visvader
Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development.
Oncogene 2005;24(30):4820-8.
2005: Corinne A Boulanger; Kay-Uwe Wagner; Gilbert H Smith
Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression.
Oncogene 2005;24(4):552-60.
2005: Kay-Uwe Wagner; Gilbert H Smith
Pregnancy and stem cell behavior.
Journal of mammary gland biology and neoplasia 2005;10(1):25-36.
2004: Magdalene K Sgagias; Kay-Uwe Wagner; Brad Hamik; Scott M Stoeger; Rebecca Spieker; L Julie Huber; Lewis A Chodosh; Kenneth H Cowan
Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS.
Cell cycle (Georgetown, Tex.) 2004;3(11):1451-6.
2004: MaLinda D Henry; Aleata A Triplett; Keon Bong Oh; Gilbert H Smith; Kay-Uwe Wagner
Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice.
Oncogene 2004;23(41):6980-5.
2004: Andrea Krempler; Yongyue Qi; Aleata A Triplett; Jianqiong Zhu; Hallgeir Rui; Kay-Uwe Wagner
Generation of a conditional knockout allele for the Janus kinase 2 (Jak2) gene in mice.
Genesis (New York, N.Y. : 2000) 2004;40(1):52-7.
2004: Marissa J Carstens; Andrea Krempler; Aleata A Triplett; Maarten van Lohuizen; Kay-Uwe Wagner
Cell cycle arrest and cell death are controlled by p53-dependent and p53-independent mechanisms in Tsg101-deficient cells.
The Journal of biological chemistry 2004;279(34):35984-94.
2004: Kay-Uwe Wagner; Andrea Krempler; Aleata A Triplett; Yongyue Qi; Nicholas M George; Jianqiong Zhu; Hallgeir Rui
Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice.
Molecular and cellular biology 2004;24(12):5510-20.
2004: Alison M Y Cheung; Andrew Elia; Ming Tsao; Susan J Done; Kay-Uwe Wagner; Lothar Hennighausen; Raza Hakem; Tak W Mak
Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice.
Cancer research 2004;64(6):1959-65.
2004: Stéphanie A Backman; Danny Ghazarian; Kelvin So; Otto Sanchez; Kay-Uwe Wagner; Lothar Hennighausen; Akira Suzuki; Ming Tsao; William B Chapman; Vuk Stambolic; Tak W Mak
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1725-30.
2004: Kay-Uwe Wagner
Models of breast cancer: quo vadis, animal modeling?
Breast cancer research : BCR 2004;6(1):31-8.
2003: Weiwen Long; Kay-Uwe Wagner; K C Kent Lloyd; Nadine Binart; Jonathan Shillingford; Lothar Hennighausen; Frank E Jones
Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.
Development (Cambridge, England) 2003;130(21):5257-68.
2003: Brian Bierie; Masahiro Nozawa; Jean-Pierre Renou; Jonathan Shillingford; Fanta Morgan; Takami Oka; Makoto M Taketo; Robert Cardiff; Keiko Miyoshi; Kay-Uwe Wagner; Gertraud W Robinson; Lothar Hennighausen
Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation.
Oncogene 2003;22(25):3875-87.
2003: Tiffany N. Seagroves; Darryl L Hadsell; Jim McManaman; Carol Palmer; Debbie Liao; Wayne McNulty; Bryan E. Welm; Kay-Uwe Wagner; Margaret Neville; Randall S Johnson
HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland.
Development (Cambridge, England) 2003;130(8):1713-24.
2003: Kay-Uwe Wagner; Andrea Krempler; Yongyue Qi; KyungRan Park; MaLinda D Henry; Aleata A Triplett; Gregory Riedlinger; Edmund B Rucker III; Lothar Hennighausen
Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues.
Molecular and cellular biology 2003;23(1):150-62.
2002: Andrea Krempler; MaLinda D Henry; Aleata A Triplett; Kay-Uwe Wagner
Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death.
The Journal of biological chemistry 2002;277(45):43216-23.
2002: Gang Li; Gertraud W Robinson; Ralf Lesche; Hilda Martinez-Diaz; Zhaorong Jiang; Nora Rozengurt; Kay-Uwe Wagner; De-Chang Wu; Timothy F Lane; Xin Liu; Lothar Hennighausen; Hong Wu
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland.
Development (Cambridge, England) 2002;129(17):4159-70.
2002: Yongzhi Cui; Keiko Miyoshi; Estefania Claudio; Ulrich Siebenlist; Frank J Gonzalez; Jodi A Flaws; Kay-Uwe Wagner; Lothar Hennighausen
Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility.
The Journal of biological chemistry 2002;277(20):17830-5.
2002: Marja T Nevalainen; Jianwu Xie; Lukas Bubendorf; Kay-Uwe Wagner; Hallgeir Rui
Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):1108-24.
2002: Kay-Uwe Wagner; Corinne A Boulanger; MaLinda D Henry; Magdalene K Sgagias; Lothar Hennighausen; Gilbert H Smith
An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal.
Development (Cambridge, England) 2002;129(6):1377-86.
2002: Gregory Riedlinger; Ryugo Okagaki; Kay-Uwe Wagner; Edmund B Rucker; Takami Oka; Keiko Miyoshi; Jodi A Flaws; Lothar Hennighausen
Bcl-x is not required for maintenance of follicles and corpus luteum in the postnatal mouse ovary.
Biology of reproduction 2002;66(2):438-44.
2001: Kay-Uwe Wagner; K McAllister; T Ward; B Davis; R Wiseman; Lothar Hennighausen
Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.
Transgenic research 2001;10(6):545-53.
2001: KD Walton; Kay-Uwe Wagner; Edmund B Rucker; Jonathan Shillingford; Keiko Miyoshi; Lothar Hennighausen
Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation.
Mechanisms of development 2001;109(2):281-93.
2001: Keiko Miyoshi; Jonathan Shillingford; Gilbert H Smith; S L Grimm; Kay-Uwe Wagner; Takami Oka; J M Rosen; Gertraud W Robinson; Lothar Hennighausen
Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium.
The Journal of cell biology 2001;155(4):531-42.
2001: Gertraud W Robinson; Kay-Uwe Wagner; Lothar Hennighausen
Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
Oncogene 2001;20(48):7115-9.
2001: H Yamashita; Marja T Nevalainen; J Xu; Matthew LeBaron; Kay-Uwe Wagner; RA Erwin; Jeffrey M Harmon; L Hennighausen; Robert A Kirken; Hallgeir Rui
Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression.
Molecular and cellular endocrinology 2001;183(1-2):151-63.
2000: Kay-Uwe Wagner; Estefania Claudio; Edmund B Rucker; Gregory Riedlinger; Christine Broussard; Pamela L Schwartzberg; Ulrich Siebenlist; Lothar Hennighausen
Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly.
Development (Cambridge, England) 2000;127(22):4949-58.
2000: Edmund B Rucker; P Dierisseau; Kay-Uwe Wagner; L Garrett; A Wynshaw-Boris; Jodi A Flaws; Lothar Hennighausen
Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis.
Molecular endocrinology (Baltimore, Md.) 2000;14(7):1038-52.
1999: Xiaoling Xu; Kay-Uwe Wagner; D Larson; Z Weaver; Cuiling Li; Thomas Ried; Lothar Hennighausen; Anthony Wynshaw-Boris; Chu-Xia Deng
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Nature genetics 1999;22(1):37-43.
1999: Kay-Uwe Wagner; P Dierisseau; Lothar Hennighausen
Assignment of the murine tumor susceptibility gene 101 (tsg101) and a processed tsg101 pseudogene (tsg101-ps1) to mouse chromosome 7 band B5 and chromosome 15 band D1 by in situ hybridization.
Cytogenetics and cell genetics 1999;84(1-2):87-8.
1998: Kay-Uwe Wagner; P Dierisseau; Edmund B Rucker; Gertraud W Robinson; Lothar Hennighausen
Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: common types of shorter transcripts are true alternative splice variants.
Oncogene 1998;17(21):2761-70.
1998: W Scott Young; E Shepard; AC DeVries; A Zimmer; Mary E LaMarca; Edward I Ginns; J Amico; R J Nelson; L Hennighausen; Kay-Uwe Wagner
Targeted reduction of oxytocin expression provides insights into its physiological roles.
Advances in experimental medicine and biology 1998;449():231-40.
1997: Kay-Uwe Wagner; W Scott Young; X Liu; Edward I Ginns; M Li; Priscilla A Furth; Lothar Hennighausen
Oxytocin and milk removal are required for post-partum mammary-gland development.
Genes and function 1997;1(4):233-44.
1997: Kay-Uwe Wagner; R J Wall; L St-Onge; P Gruss; Anthony Wynshaw-Boris; L Garrett; M Li; Priscilla A Furth; L Hennighausen
Cre-mediated gene deletion in the mammary gland.
Nucleic acids research 1997;25(21):4323-30.
1997: Lothar Hennighausen; Gertraud W Robinson; Kay-Uwe Wagner; X Liu
Developing a mammary gland is a stat affair.
Journal of mammary gland biology and neoplasia 1997;2(4):365-72.
1997: Minglin Li; Xibao Liu; G Robinson; U Bar-Peled; Kay-Uwe Wagner; W Scott Young; L Hennighausen; Priscilla A Furth
Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3425-30.
1997: Lothar Hennighausen; Gertraud W Robinson; Kay-Uwe Wagner; W Liu
Prolactin signaling in mammary gland development.
The Journal of biological chemistry 1997;272(12):7567-9.
1997: X Liu; Gertraud W Robinson; Kay-Uwe Wagner; L Garrett; A Wynshaw-Boris; L Hennighausen
Stat5a is mandatory for adult mammary gland development and lactogenesis.
Genes & development 1997;11(2):179-86.
1996: W Scott Young; E Shepard; J Amico; Lothar Hennighausen; Kay-Uwe Wagner; Mary E LaMarca; CE McKinney; Edward I Ginns
Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition.
Journal of neuroendocrinology 1996;8(11):847-53.