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hans-dieter royer

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Brigitte Royer-Pokora; Maike Busch; Manfred Beier; Constanze Duhme; Carmen de Torres; Jaume Mora; Artur Brandt; hans-dieter royer
Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm.
Karsten Jürchott; Ralf-Jürgen Kuban; Till Krech; Nils Blüthgen; Ulrike Stein; Wolfgang Walther; Christian Friese; Szymon M Kiełbasa; Ute Ungethüm; Per Lund; Thomas Knösel; Wolfgang Kemmner; Markus Morkel; Johannes Fritzmann; Peter M Schlag; Walter Birchmeier; Tammo Krueger; Silke Sperling; Christine Sers; hans-dieter royer; Hanspeter Herzel; Reinhold Schäfer
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Eva M Gosepath; Niels Eckstein; Alexandra Hamacher; Kati Servan; Georg von Jonquieres; Hermann Lage; Balazs Györffy; hans-dieter royer; Matthias U Kassack
Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1.

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2010: Brigitte Royer-Pokora; Maike Busch; Manfred Beier; Constanze Duhme; Carmen de Torres; Jaume Mora; Artur Brandt; hans-dieter royer
Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm.
Human molecular genetics 2010;19(9):1651-68.
2010: Karsten Jürchott; Ralf-Jürgen Kuban; Till Krech; Nils Blüthgen; Ulrike Stein; Wolfgang Walther; Christian Friese; Szymon M Kiełbasa; Ute Ungethüm; Per Lund; Thomas Knösel; Wolfgang Kemmner; Markus Morkel; Johannes Fritzmann; Peter M Schlag; Walter Birchmeier; Tammo Krueger; Silke Sperling; Christine Sers; hans-dieter royer; Hanspeter Herzel; Reinhold Schäfer
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
PLoS genetics 2010;6(12):e1001231.
2008: Eva M Gosepath; Niels Eckstein; Alexandra Hamacher; Kati Servan; Georg von Jonquieres; Hermann Lage; Balazs Györffy; hans-dieter royer; Matthias U Kassack
Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1.
International journal of cancer. Journal international du cancer 2008;123(9):2013-9.
2008: Manik Chatterjee; Christoph Rancso; Thorsten Stühmer; Niels Eckstein; Mindaugas Andrulis; Christian Gerecke; Heike Lorentz; hans-dieter royer; Ralf C Bargou
The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Blood 2008;111(7):3714-22.
2008: Niels Eckstein; Kati Servan; Luc Girard; Di Cai; Georg von Jonquieres; Ulrich Jaehde; Matthias U Kassack; Adi F Gazdar; John D Minna; hans-dieter royer
Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.
The Journal of biological chemistry 2008;283(2):739-50.
2007: Christina Evers; Manfred Beier; Anne Poelitz; Barbara Hildebrandt; Kati Servan; Matthias Drechsler; Ulrich Germing; hans-dieter royer; Brigitte Royer-Pokora
Molecular definition of chromosome arm 5q deletion end points and detection of hidden aberrations in patients with myelodysplastic syndromes and isolated del(5q) using oligonucleotide array CGH.
Genes, chromosomes & cancer 2007;46(12):1119-28.
2006: Edgar Grinstein; Ying Shan; Leonid Karawajew; Peter J F Snijders; Chris J L M Meijer; hans-dieter royer; Peter Wernet
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation.
The Journal of biological chemistry 2006;281(31):22223-35.
2006: Gabriel Glockzin; Klaus Mantwill; Karsten Jurchott; Alexandra Bernshausen; Axel Ladhoff; hans-dieter royer; Bernd Gansbacher; Per Sonne Holm
Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.
Journal of virology 2006;80(8):3904-11.
2005: Ulrike Stein; Stephan Bergmann; George L Scheffer; Rik J Scheper; hans-dieter royer; Peter M Schlag; Wolfgang Walther
YB-1 facilitates basal and 5-fluorouracil-inducible expression of the human major vault protein (MVP) gene.
Oncogene 2005;24(22):3606-18.
2005: Stephan Bergmann; Brigitte Royer-Pokora; Ellen Fietze; Karsten Jürchott; Barbara Hildebrandt; Detlef Trost; Frauke Leenders; Jenny-Chang Claude; Franz Theuring; Ralf C Bargou; Manfred Dietel; hans-dieter royer
YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.
Cancer research 2005;65(10):4078-87.
2004: Elena Klenova; Alison C Scott; Julian Roberts; Shaharum Shamsuddin; Elizabeth A Lovejoy; Stephan Bergmann; Vivien J Bubb; hans-dieter royer; John P Quinn
YB-1 and CTCF differentially regulate the 5-HTT polymorphic intron 2 enhancer which predisposes to a variety of neurological disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(26):5966-73.
2004: Christian Gessner; Christiane Woischwill; Axel Schumacher; Uta Liebers; Hartmut Kuhn; Peter Stiehl; Karsten Jürchott; hans-dieter royer; Christian Witt; Gerhard Wolff
Nuclear YB-1 expression as a negative prognostic marker in nonsmall cell lung cancer.
The European respiratory journal 2004;23(1):14-9.
2004: Per Sonne Holm; Hermann Lage; Stephan Bergmann; Karsten Jürchott; Gabriel Glockzin; Alexandra Bernshausen; Klaus Mantwill; Axel Ladhoff; Anke Wichert; Joe S Mymryk; Thomas Ritter; Manfred Dietel; Bernd Gänsbacher; hans-dieter royer
Multidrug-resistant cancer cells facilitate E1-independent adenoviral replication: impact for cancer gene therapy.
Cancer research 2004;64(1):322-8.
2003: Karsten Jurchott; Stephan Bergmann; Ulrike Stein; Wolfgang Walther; Martin Janz; Isabella Manni; Giulia Piaggio; Ellen Fietze; Manfred Dietel; hans-dieter royer
YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
The Journal of biological chemistry 2003;278(30):27988-96.
2003: Ute Raffetseder; Björn Frye; Thomas Rauen; Karsten Jürchott; hans-dieter royer; Petra Lynen Jansen; Peter R Mertens
Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection.
The Journal of biological chemistry 2003;278(20):18241-8.
2002: Edgar Grinstein; Peter Wernet; Peter J F Snijders; Frank Rösl; Inge Weinert; Wentao Jia; Regine Kraft; Christiane Schewe; Michael Schwabe; Steffen Hauptmann; Manfred Dietel; Chris J L M Meijer; hans-dieter royer
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
The Journal of experimental medicine 2002;196(8):1067-78.
2002: Per Sonne Holm; Stephan Bergmann; Karsten Jurchott; Hermann Lage; Karsten Brand; Axel Ladhoff; Klaus Mantwill; David T Curiel; Matthias Dobbelstein; Manfred Dietel; Bernd Gansbacher; hans-dieter royer
YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.
The Journal of biological chemistry 2002;277(12):10427-34.
2002: Edgar Grinstein; Franziska Jundt; Inge Weinert; Peter Wernet; hans-dieter royer
Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells.
Oncogene 2002;21(10):1485-92.
2002: Martin Janz; Nadia Harbeck; Peer Dettmar; Ursula Berger; Anja Schmidt; Karsten Jürchott; Manfred Schmitt; hans-dieter royer
Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1.
International journal of cancer. Journal international du cancer 2002;97(3):278-82.
2001: hans-dieter royer
Centenary Nobel Prize in Physiology or Medicine for the cell cycle.
Journal of molecular medicine (Berlin, Germany) 2001;79(12):683-5.
2001: Ulrike Stein; Karsten Jürchott; Wolfgang Walther; Stephan Bergmann; Peter M Schlag; hans-dieter royer
Hyperthermia-induced nuclear translocation of transcription factor YB-1 leads to enhanced expression of multidrug resistance-related ABC transporters.
The Journal of biological chemistry 2001;276(30):28562-9.
2000: C Y Chen; Roberto Gherzi; J S Andersen; Guido Gaietta; Karsten Jürchott; hans-dieter royer; M Mann; Michael Karin
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation.
Genes & development 2000;14(10):1236-48.
1999: Franziska Jundt; Ioannis Anagnostopoulos; Kurt Bommert; Florian Emmerich; G Müller; Hans-Dieter Foss; hans-dieter royer; Harald Stein; Bernd Dörken
Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils.
Blood 1999;94(6):2065-71.
1997: Ralf C Bargou; Florian Emmerich; Daniel Krappmann; Kurt Bommert; Markus Y Mapara; W Arnold; hans-dieter royer; Edgar Grinstein; A Greiner; Claus Scheidereit; Bernd Dörken
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
The Journal of clinical investigation 1997;100(12):2961-9.
1997: Ralf C Bargou; Karsten Jürchott; C Wagener; Stephan Bergmann; Sylvia Metzner; Kurt Bommert; Markus Y Mapara; K J Winzer; Manfred Dietel; Bernd Dörken; hans-dieter royer
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression.
Nature medicine 1997;3(4):447-50.
1996: C Wagener; Ralf C Bargou; Peter Daniel; Kurt Bommert; Markus Y Mapara; hans-dieter royer; Bernd Dörken
Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis.
International journal of cancer. Journal international du cancer 1996;67(1):138-41.
1996: Ralf C Bargou; C Wagener; Kurt Bommert; Markus Y Mapara; Peter Daniel; W Arnold; M Dietel; H Guski; A Feller; hans-dieter royer; Bernd Dörken
Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
The Journal of clinical investigation 1996;97(11):2651-9.
1996: Ralf C Bargou; C Leng; Daniel Krappmann; Florian Emmerich; Markus Y Mapara; Kurt Bommert; hans-dieter royer; Claus Scheidereit; Bernd Dörken
High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells.
Blood 1996;87(10):4340-7.
1996: E Grinstein; I Weinert; B Droese; M Pagano; hans-dieter royer
Cell cycle regulation of nuclear factor p32 DNA-binding activity by novel phase-specific inhibitors.
The Journal of biological chemistry 1996;271(16):9215-22.
1996: Ralf C Bargou; C Wagener; Kurt Bommert; W Arnold; Peter Daniel; Markus Y Mapara; E Grinstein; hans-dieter royer; Bernd Dörken
Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice.
The Journal of experimental medicine 1996;183(3):1205-13.
1995: E Grinstein; hans-dieter royer
Multiple octamer-binding proteins are targets for the cell cycle-regulated nuclear inhibitor I-92.
DNA and cell biology 1995;14(6):493-500.
1995: Ralf C Bargou; Peter Daniel; Markus Y Mapara; Kurt Bommert; C Wagener; B Kallinich; hans-dieter royer; Bernd Dörken
Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis.
International journal of cancer. Journal international du cancer 1995;60(6):854-9.
1993: W Hofmann; hans-dieter royer; Matthias Drechsler; S Schneider; Brigitte Royer-Pokora
Characterization of the transcriptional regulatory region of the human WT1 gene.
Oncogene 1993;8(11):3123-32.
1992: T Bauknecht; Peter Angel; hans-dieter royer; Harald zur Hausen
Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.
The EMBO journal 1992;11(12):4607-17.
1992: D D Spitkovsky; Brigitte Royer-Pokora; Hajo Delius; F Kisseljov; N A Jenkins; D J Gilbert; N G Copeland; hans-dieter royer
Tissue restricted expression and chromosomal localization of the YB-1 gene encoding a 42 kD nuclear CCAAT binding protein.
Nucleic acids research 1992;20(4):797-803.
1991: J Weitz; M Kopun; M Stoehr; I Napierski; hans-dieter royer
A novel nuclear inhibitor I-92 regulates DNA binding activity of octamer binding protein p92 during the cell cycle.
Nucleic acids research 1991;19(20):5725-30.
1991: hans-dieter royer; M P Freyaldenhoven; I Napierski; D D Spitkovsky; T Bauknecht; N Dathan
Delineation of human papillomavirus type 18 enhancer binding proteins: the intracellular distribution of a novel octamer binding protein p92 is cell cycle regulated.
Nucleic acids research 1991;19(9):2363-71.
1989: M P Freyaldenhoven; Brigitte Royer-Pokora; I Napierski; hans-dieter royer
DNA binding proteins present in guanidinium isothiocyanate lysates of cells are suitable for specific binding site blotting.
Nucleic acids research 1989;17(21):8891.
1987: hans-dieter royer; Ellis L Reinherz
T lymphocytes: ontogeny, function, and relevance to clinical disorders.
The New England journal of medicine 1987;317(18):1136-42.
1987: hans-dieter royer; Ellis L Reinherz
The human T cell receptor for antigen: structure, ontogeny and gene expression.
Behring Institute Mitteilungen 1987;(81):1-14.
1987: hans-dieter royer; Ellis L Reinherz
Multiple nuclear proteins bind upstream sequences in the promotor region of a T-cell receptor beta-chain variable-region gene: evidence for tissue specificity.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(1):232-6.
1986: R E Schmidt; G T Bartley; S S Lee; J F Daley; hans-dieter royer; H Levine; Ellis L Reinherz; S F Schlossman; Jerome Ritz
Expression of the NKTa clonotype in a series of human natural killer clones with identical cytotoxic specificity.
The Journal of experimental medicine 1986;163(4):812-25.
1986: Ellis L Reinherz; hans-dieter royer; T J Campen; D Ramarli; H C Chang; Oreste Acuto
The structure and function of the T3-Ti molecular complex on human T lymphocytes.
Symposium on Fundamental Cancer Research 1986;38():3-30.
1986: Ellis L Reinherz; hans-dieter royer; T J Campen; D Ramarli; Marina Fabbi; Oreste Acuto
The ontogeny, structure and function of the human T lymphocyte receptor for antigen and major histocompatibility complex.
Biochemical Society symposium 1986;51():211-32.
1985: hans-dieter royer; T J Campen; D Ramarli; H C Chang; Oreste Acuto; Ellis L Reinherz
The human T lymphocyte receptor complex for antigen and MHC.
Behring Institute Mitteilungen 1985;(77):1-21.
1985: hans-dieter royer; D Ramarli; Oreste Acuto; T J Campen; Ellis L Reinherz
Genes encoding the T-cell receptor alpha and beta subunits are transcribed in an ordered manner during intrathymic ontogeny.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(16):5510-4.
1985: Peter Barker; hans-dieter royer; F H Ruddle; Ellis L Reinherz
Regional location of T cell receptor gene Ti alpha on human chromosome 14.
The Journal of experimental medicine 1985;162(1):387-92.
1985: Jerome Ritz; T J Campen; R E Schmidt; hans-dieter royer; T Hercend; R E Hussey; Ellis L Reinherz
Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones.
Science (New York, N.Y.) 1985;228(4707):1540-3.
1985: hans-dieter royer; T J Campen; D Ramarli; H C Chang; Oreste Acuto; Ellis L Reinherz
Molecular aspects of human T lymphocyte antigen recognition.
Transplantation 1985;39(6):571-82.
1985: Oreste Acuto; T J Campen; hans-dieter royer; R E Hussey; C B Poole; Ellis L Reinherz
Molecular analysis of T cell receptor (Ti) variable region (V) gene expression. Evidence that a single Ti beta V gene family can be used in formation of V domains on phenotypically and functionally diverse T cell populations.
The Journal of experimental medicine 1985;161(6):1326-43.
1985: Oreste Acuto; Marina Fabbi; Armand Bensussan; C Milanese; T J Campen; hans-dieter royer; Ellis L Reinherz
The human T-cell receptor.
Journal of clinical immunology 1985;5(3):141-57.
1984: hans-dieter royer; Oreste Acuto; Marina Fabbi; R Tizard; K Ramachandran; J E Smart; Ellis L Reinherz
Genes encoding the Ti beta subunit of the antigen/MHC receptor undergo rearrangement during intrathymic ontogeny prior to surface T3-Ti expression.
Cell 1984;39(2 Pt 1):261-6.
1984: G N Gaulton; M S Co; hans-dieter royer; M I Greene
Anti-idiotypic antibodies as probes of cell surface receptors.
Molecular and cellular biochemistry 1984;65(1):5-21.
1984: Peter Barker; F H Ruddle; hans-dieter royer; Oreste Acuto; Ellis L Reinherz
Chromosomal location of human T-cell receptor gene Ti beta.
Science (New York, N.Y.) 1984;226(4672):348-9.
1984: Ellis L Reinherz; Oreste Acuto; Marina Fabbi; Armand Bensussan; C Milanese; hans-dieter royer; S C Meuer; S F Schlossman
Clonotypic surface structure on human T lymphocytes: functional and biochemical analysis of the antigen receptor complex.
Immunological reviews 1984;81():95-129.
1984: hans-dieter royer; Armand Bensussan; Oreste Acuto; Ellis L Reinherz
Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex.
The Journal of experimental medicine 1984;160(3):947-52.
1984: Oreste Acuto; Marina Fabbi; J Smart; C B Poole; J Protentis; hans-dieter royer; S F Schlossman; Ellis L Reinherz
Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3851-5.
1980: H Sano; hans-dieter royer; R Sager
Identification of 5-methylcytosine in DNA fragments immobilized on nitrocellulose paper.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(6):3581-5.
1979: U Henning; hans-dieter royer; R M Teather; I Hindennach; C P Hollenberg
Cloning of the structural gene (ompA) for an integral outer membrane protein of Escherichia coli K-12.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(9):4360-4.
1979: hans-dieter royer; C P Hollenberg
Mapping of Escherichia coli RNA polymerase binding sites on 2-micrometers DNA from Saccharomyces cerevisiae. Heterogeneity within the inverted duplication and evidence for an eukaryotic invertible DNA sequence.
Plasmid 1979;2(3):403-16.
1979: A Degelmann; hans-dieter royer; C P Hollenberg
The organization of the ribosomal RNA genes of Chironomus tentans and some closely related species.
Chromosoma 1979;71(3):263-81.
1978: B Flehmig; hans-dieter royer; H J Gerth
Isolation of single stranded DNA from purified hepatitis A-virus.
Zeitschrift für Naturforschung. Section C: Biosciences 1978;33(7-8):594-7.
1977: hans-dieter royer; C P Hollenberg
Saccharomyces cerevisiae 2-mum DNA. An analysis of the monomer and its multimers by electron microscopy.
Molecular & general genetics : MGG 1977;150(3):271-84.
1976: R Wells; hans-dieter royer; C P Hollenberg
Non Xenopus-like DNA sequence organization in the Chironomus tentans genome.
Molecular & general genetics : MGG 1976;147(1):45-51.
1976: C P Hollenberg; A Degelmann; B Kustermann-Kuhn; hans-dieter royer
Characterization of 2-mum DNA of Saccharomyces cerevisiae by restriction fragment analysis and integration in an Escherichia coli plasmid.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(6):2072-6.
1976: C P Hollenberg; B Kustermann-Kuhn; hans-dieter royer
Synthesis of high molecular weight polypeptides in Escherichia coli minicells directed by cloned Saccharomyces cerevisiae 2-micron DNA.
Gene 1976;1(1):33-47.