FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jens Brüning

Research Profile

Living Beings

Physiology

Chemicals & Drugs

Disorders

Anatomy

Concepts & Ideas

Body Weight

Co-author Network

Publications

TOP 3
Sophie M Steculorum; Merly C Vogt; Jens C Brüning
Perinatal programming of metabolic diseases: role of insulin in the development of hypothalamic neurocircuits.
Jan-Wilhelm Kornfeld; Hayley T Nicholls; Ludger Scheja; Jost Seibler; Markus Stoffel; Merly C Vogt; Anna M Wolf; Silvia Cereghini; Cécile Haumaitre; Joerg Heeren; Karolin Herrmanns; Uwe Knippschild; A Christine Könner; Catherina Baitzel; Jens C Brüning
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b.
Oliver Stöhr; Michael Udelhoven; F Thomas Wunderlich; Johanna Zemva; Jens C Brüning; Marianne Ernst; Susanna Freude; Moritz M Hettich; Wilhelm Krone; Lorna Moll; Katharina Schilbach; Markus Schubert
Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jens Brüning (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Sophie M Steculorum; Merly C Vogt; Jens C Brüning
Perinatal programming of metabolic diseases: role of insulin in the development of hypothalamic neurocircuits.
Endocrinology and metabolism clinics of North America 2013;42(1):149-64.
2013: Jan-Wilhelm Kornfeld; Hayley T Nicholls; Ludger Scheja; Jost Seibler; Markus Stoffel; Merly C Vogt; Anna M Wolf; Silvia Cereghini; Cécile Haumaitre; Joerg Heeren; Karolin Herrmanns; Uwe Knippschild; A Christine Könner; Catherina Baitzel; Jens C Brüning
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b.
Nature 2013;494(7435):111-5.
2013: Oliver Stöhr; Michael Udelhoven; F Thomas Wunderlich; Johanna Zemva; Jens C Brüning; Marianne Ernst; Susanna Freude; Moritz M Hettich; Wilhelm Krone; Lorna Moll; Katharina Schilbach; Markus Schubert
Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.
Age (Dordrecht, Netherlands) 2013;35(1):83-101.
2012: Eva Rother; Eva Tsaousidou; Ari Waisman; Bengt F Belgardt; Brigitte Hampel; Martin G Myers; Jens C Brüning
Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):18132-7.
2012: A Christine Könner; Jens C Brüning
Selective insulin and leptin resistance in metabolic disorders.
Cell metabolism 2012;16(2):144-52.
2012: Katrin Blumbach; Jens C Brüning; Bengt F Belgardt; Harald W A Ehlen; Donald Gullberg; Ralf Hallinger; Thomas Krieg; Anja Niehoff; Markus Schmitz; Markus Schubert; Jan-Niklas Schulz; Beate Eckes
Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels.
The Journal of biological chemistry 2012;287(9):6431-40.
2011: Tim Klöckener; Peter Kloppenburg; Bradford B Lowell; Lars Paeger; Jong-Woo Sohn; Linda A W Verhagen; Kevin W Williams; Jeffrey M Zigman; Harveen Dhillon; Joel K Elmquist; Brigitte Hampel; Simon Hess; Tamas L Horvath; Andreas Husch; Bengt F Belgardt; Jens C Brüning
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Nature neuroscience 2011;14(7):911-8.
2011: A Christine Könner; Simon Hess; Sulay Tovar; Andrea Mesaros; Carmen Sánchez-Lasheras; Nadine Evers; Linda A W Verhagen; Hella S Brönneke; André Kleinridders; Brigitte Hampel; Peter Kloppenburg; Jens C Brüning
Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis.
Cell metabolism 2011;13(6):720-8.
2011: Sabine D Jordan; Markus Krüger; Diana M Willmes; Nora Redemann; F Thomas Wunderlich; Hella S Brönneke; Carsten Merkwirth; Hamid Kashkar; Vesa M Olkkonen; Thomas Böttger; Thomas Braun; Jost Seibler; Jens C Brüning
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.
Nature cell biology 2011;13(4):434-46.
2011: A Christine Könner; Jens C Brüning
Toll-like receptors: linking inflammation to metabolism.
Trends in endocrinology and metabolism: TEM 2011;22(1):16-23.
2010: Bengt F Belgardt; Jens C Brüning
CNS leptin and insulin action in the control of energy homeostasis.
Annals of the New York Academy of Sciences 2010;1212():97-113.
2010: Sabine D Jordan; A Christine Könner; Jens C Brüning
Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis.
Cellular and molecular life sciences : CMLS 2010;67(19):3255-73.
2010: F Thomas Wunderlich; Peter Ströhle; A Christine Könner; Sabine Gruber; Sulay Tovar; Hella S Brönneke; Lisa Juntti-Berggren; Luo-Sheng Li; Nico van Rooijen; Claude Libert; Per-Olof Berggren; Jens C Brüning
Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action.
Cell metabolism 2010;12(3):237-49.
2010: Bengt F Belgardt; Jan Mauer; Jens C Brüning
Novel roles for JNK1 in metabolism.
Aging 2010;2(9):621-6.
2010: Bhagirath Chaurasia; Jan Mauer; Linda Koch; Julia Goldau; Anja-Sterner Kock; Jens C Brüning
Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages.
Molecular and cellular biology 2010;30(17):4354-66.
2010: Jan Mauer; Bhagirath Chaurasia; Leona Plum; Thomas Quast; Brigitte Hampel; Matthias Blüher; Waldemar Kolanus; C Ronald Kahn; Jens C Brüning
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance.
PLoS genetics 2010;6(5):e1000938.
2010: Bengt F Belgardt; Jan Mauer; F Thomas Wunderlich; Marianne B Ernst; Martin Pal; Gabriele Spohn; Hella S Brönneke; Susanne Brodesser; Brigitte Hampel; Astrid C Schauss; Jens C Brüning
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):6028-33.
2010: Carmen Sánchez-Lasheras; A Christine Könner; Jens C Brüning
Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators.
Frontiers in neuroendocrinology 2010;31(1):4-15.
2009: André Kleinridders; A Christine Könner; Jens C Brüning
CNS-targets in control of energy and glucose homeostasis.
Current opinion in pharmacology 2009;9(6):794-804.
2009: Bengt F Belgardt; Tomoo Okamura; Jens C Brüning
Hormone and glucose signalling in POMC and AgRP neurons.
The Journal of physiology 2009;587(Pt 22):5305-14.
2009: André Kleinridders; Dominik Schenten; A Christine Könner; Bengt F Belgardt; Jan Mauer; Tomoo Okamura; F Thomas Wunderlich; Ruslan Medzhitov; Jens C Brüning
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.
Cell metabolism 2009;10(4):249-59.
2009: Susanna Freude; Moritz M Hettich; Christina Schumann; Oliver Stöhr; Linda Koch; Christoph Köhler; Michael Udelhoven; Uschi Leeser; Marita Müller; Naoto Kubota; Takashi Kadowaki; Wilhelm Krone; Hannsjörg Schröder; Jens C Brüning; Markus Schubert
Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(10):3315-24.
2009: Marianne B Ernst; Claudia M Wunderlich; Simon Hess; Moritz Paehler; Andrea Mesaros; Sergei B Koralov; André Kleinridders; Andreas Husch; Heike Münzberg; Brigitte Hampel; Jens Alber; Peter Kloppenburg; Jens C Brüning; F Thomas Wunderlich
Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(37):11582-93.
2009: Benjamin Yazdanpanah; Katja Wiegmann; Vladimir Tchikov; Oleg Krut; Carola Pongratz; Michael Schramm; Andre Kleinridders; Thomas Wunderlich; Hamid Kashkar; Olaf Utermöhlen; Jens C Brüning; Stefan Schütze; Martin Krönke
Riboflavin kinase couples TNF receptor 1 to NADPH oxidase.
Nature 2009;460(7259):1159-63.
2009: A Christine Könner; Tim Klöckener; Jens C Brüning
Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond.
Physiology & behavior 2009;97(5):632-8.
2009: André Kleinridders; Hans-Martin Pogoda; Sigrid Irlenbusch; Neil Smyth; Csaba Koncz; Matthias Hammerschmidt; Jens C Brüning
PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis.
Molecular and cellular biology 2009;29(11):3173-85.
2009: george garinis; Lieneke M Uittenboogaard; Heike Stachelscheid; Maria Fousteri; Wilfred van Ijcken; Timo M Breit; Harry van Steeg; Leon H F Mullenders; Gijsbertus T J van der Horst; Jens C Brüning; Carien M Niessen; Jan H J Hoeijmakers; Björn Schumacher
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Nature cell biology 2009;11(5):604-15.
2008: Susanna Freude; Uschi Leeser; Marita Müller; Moritz M Hettich; Michael Udelhoven; Katharina Schilbach; Kazuyuki Tobe; Takashi Kadowaki; Christoph Köhler; Hannsjörg Schröder; Wilhelm Krone; Jens C Brüning; Markus Schubert
IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.
Journal of neurochemistry 2008;107(4):907-17.
2008: Heike Stachelscheid; Hady Ibrahim; Linda Koch; Annika Schmitz; Michael Tscharntke; F Thomas Wunderlich; Jeanie Scott; Christian Michels; Claudia Wickenhauser; Ingo Haase; Jens C Brüning; Carien M Niessen
Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.
The EMBO journal 2008;27(15):2091-101.
2008: Linda Koch; F Thomas Wunderlich; Jost Seibler; A Christine Könner; Brigitte Hampel; Sigrid Irlenbusch; Georg Brabant; C Ronald Kahn; Frieder Schwenk; Jens C Brüning
Central insulin action regulates peripheral glucose and fat metabolism in mice.
The Journal of clinical investigation 2008;118(6):2132-47.
2008: Eva Rother; A Christine Könner; Jens C Brüning
Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism.
American journal of physiology. Endocrinology and metabolism 2008;294(5):E810-6.
2008: Bengt F Belgardt; Andreas Husch; Eva Rother; Marianne B Ernst; F Thomas Wunderlich; Brigitte Hampel; Tim Klöckener; Dario Alessi; Peter Kloppenburg; Jens C Brüning
PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.
Cell metabolism 2008;7(4):291-301.
2008: Andrea Mesaros; Sergei B Koralov; Eva Rother; F Thomas Wunderlich; Marianne B Ernst; Gregory S Barsh; Klaus Rajewsky; Jens C Brüning
Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.
Cell metabolism 2008;7(3):236-48.
2008: F Thomas Wunderlich; Tom Luedde; Stephan Singer; Marc Schmidt-Supprian; Julia Baumgartl; Peter Schirmacher; Manolis Pasparakis; Jens C Brüning
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1297-302.
2007: Leona Plum; Eva Rother; Heike Münzberg; F Thomas Wunderlich; Donald A Morgan; Brigitte Hampel; Marya Shanabrough; Ruth Janoschek; A Christine Könner; Jens Alber; Akira Suzuki; Wilhelm Krone; Tamas L Horvath; Kamal Rahmouni; Jens C Brüning
Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.
Cell metabolism 2007;6(6):431-45.
2007: Nadine Hövelmeyer; F Thomas Wunderlich; Ramin Massoumi; Charlotte G Jakobsen; Jian Song; Marcus A Wörns; Carsten Merkwirth; Andrew Kovalenko; Monique Aumailley; Dennis Strand; Jens C Brüning; Peter R Galle; David Wallach; Reinhard Fässler; Ari Waisman
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.
The Journal of experimental medicine 2007;204(11):2615-27.
2007: A Christine Könner; Ruth Janoschek; Leona Plum; Sabine D Jordan; Eva Rother; Xiaosong Ma; Chun Xu; Pablo J Enriori; Brigitte Hampel; Gregory S Barsh; C Ronald Kahn; Michael Alexander cowley; Frances M Ashcroft; Jens C Brüning
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
Cell metabolism 2007;5(6):438-49.
2007: Xiaosong Ma; Lejla Zubcevic; Jens C Brüning; Frances M Ashcroft; Denis Burdakov
Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1529-33.
2007: Jost Seibler; Andre Kleinridders; Birgit Küter-Luks; Sandra Niehaves; Jens C Brüning; Frieder Schwenk
Reversible gene knockdown in mice using a tight, inducible shRNA expression system.
Nucleic acids research 2007;35(7):e54.
2006: Ruth Janoschek; Leona Plum; Linda Koch; Heike Münzberg; Sabrina Diano; Marya Shanabrough; Werner Muller; Tamas L Horvath; Jens C Brüning
gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(28):10707-12.
2006: Leona Plum; Bengt F Belgardt; Jens C Brüning
Central insulin action in energy and glucose homeostasis.
The Journal of clinical investigation 2006;116(7):1761-6.
2006: Leona Plum; Xiaosong Ma; Brigitte Hampel; Nina Balthasar; Roberto Coppari; Heike Münzberg; Marya Shanabrough; Denis Burdakov; Eva Rother; Ruth Janoschek; Jens Alber; Bengt F Belgardt; Linda Koch; Jost Seibler; Frieder Schwenk; Csaba Fekete; Akira Suzuki; Tak W Mak; Wilhelm Krone; Tamas L Horvath; Frances M Ashcroft; Jens C Brüning
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
The Journal of clinical investigation 2006;116(7):1886-901.
2006: Julia Baumgartl; Stephanie Baudler; Maximilian Scherner; Vladimir Babaev; Liza Hayes; Jill Suttles; Marcia McDuffie; Kazuyuki Tobe; Takashi Kadowaki; Sergio Fazio; C Ronald Kahn; Gökhan S Hotamisligil; Wilhelm Krone; MacRae F Linton; Jens C Brüning
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.
Cell metabolism 2006;3(4):247-56.
2005: Eva Gropp; Marya Shanabrough; Erzsebet Borok; Allison W Xu; Ruth Janoschek; Thorsten Buch; Leona Plum; Nina Balthasar; Brigitte Hampel; Ari Waisman; Gregory S Barsh; Tamas L Horvath; Jens C Brüning
Agouti-related peptide-expressing neurons are mandatory for feeding.
Nature neuroscience 2005;8(10):1289-91.
2005: Leona Plum; F Thomas Wunderlich; Stephanie Baudler; Wilhelm Krone; Jens C Brüning
Transgenic and knockout mice in diabetes research: novel insights into pathophysiology, limitations, and perspectives.
Physiology (Bethesda, Md.) 2005;20():152-61.
2005: Simon J Fisher; Jens C Brüning; Scott Lannon; C Ronald Kahn
Insulin signaling in the central nervous system is critical for the normal sympathoadrenal response to hypoglycemia.
Diabetes 2005;54(5):1447-51.
2005: Stephanie Baudler; Julia Baumgartl; Brigitte Hampel; Thorsten Buch; Ari Waisman; Clifford M Snapper; Wilhelm Krone; Jens C Brüning
Insulin-like growth factor-1 controls type 2 T cell-independent B cell response.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5516-25.
2005: Leona Plum; Markus Schubert; Jens C Brüning
The role of insulin receptor signaling in the brain.
Trends in endocrinology and metabolism: TEM 2005;16(2):59-65.
2005: Jost Seibler; Birgit Küter-Luks; Heidrun Kern; Sandra Streu; Leona Plum; Jan Mauer; Ralf Kühn; Jens C Brüning; Frieder Schwenk
Single copy shRNA configuration for ubiquitous gene knockdown in mice.
Nucleic acids research 2005;33(7):e67.
2004: Markus Schubert; Dinesh Gautam; David Surjo; Kojihiko Ueki; Stephanie Baudler; Dominic Schubert; Tatsuya Kondo; Jens Alber; Norbert Galldiks; Eckehardt Küstermann; Saskia Arndt; Andreas H Jacobs; Wilhelm Krone; C Ronald Kahn; Jens C Brüning
Role for neuronal insulin resistance in neurodegenerative diseases.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3100-5.
2004: Mathias Röhl; Manolis Pasparakis; Stephanie Baudler; Julia Baumgartl; Dinesh Gautam; Marion Huth; Rossana De Lorenzi; Wilhelm Krone; Klaus Rajewsky; Jens C Brüning
Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.
The Journal of clinical investigation 2004;113(3):474-81.
2003: Stephanie Baudler; Wilhelm Krone; Jens C Brüning
Genetic manipulation of the insulin signalling cascade in mice--potential insight into the pathomechanism of type 2 diabetes.
Best practice & research. Clinical endocrinology & metabolism 2003;17(3):431-43.
2003: Jens C Brüning; Philipp Lingohr; Jennifer A Gillette; Bettina Hanstein; Haluk Avci; Wilhelm Krone; Dirk Müller-Wieland; Jorg Kotzka
Estrogen receptor-alpha and Sp1 interact in the induction of the low density lipoprotein-receptor.
The Journal of steroid biochemistry and molecular biology 2003;86(2):113-21.
2003: Frieder Schwenk; Branko Zevnik; Jens C Brüning; Mathias Röhl; Antje Willuweit; Anja Rode; Thomas Hennek; Gunther Kauselmann; Rudolf Jaenisch; Ralf Kühn
Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics.
Molecular and cellular biology 2003;23(11):3982-9.
2003: Kazuhisa Maeda; Teo Uysal; Liza Hayes; Cem Z Görgün; Genichi Atsumi; Rex A Parker; Jens C Brüning; Ann Vogel Hertzel; David A Bernlohr; Gökhan S Hotamisligil
Role of the fatty acid binding protein mal1 in obesity and insulin resistance.
Diabetes 2003;52(2):300-7.
2002: Enza Distefano; Maria Marino; Jennifer A Gillette; Bettina Hanstein; Valentina Pallottini; Jens C Brüning; Wilhelm Krone; Anna Trentalance
Role of tyrosine kinase signaling in estrogen-induced LDL receptor gene expression in HepG2 cells.
Biochimica et biophysica acta 2002;1580(2-3):145-9.
2000: Jens C Brüning; Dinesh Gautam; Deborah J Burks; Jennifer A Gillette; Markus Schubert; P C Orban; R Klein; Wilhelm Krone; Dirk Müller-Wieland; C Ronald Kahn
Role of brain insulin receptor in control of body weight and reproduction.
Science (New York, N.Y.) 2000;289(5487):2122-5.
2000: Jonathon Winnay; Jens C Brüning; Deborah J Burks; C Ronald Kahn
Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts.
The Journal of biological chemistry 2000;275(14):10545-50.
2000: Birgit Knebel; Jorg Kotzka; Haluk Avci; Martina Schiller; Jens C Brüning; Martin Hafner; Wilhelm Krone; Dirk Müller-Wieland
Characterization of a postreceptor signaling defect that impairs cfos expression in cultured fibroblasts of a patient with insulin resistance.
Biochemical and biophysical research communications 2000;268(2):577-82.
2000: C Ronald Kahn; Jens C Brüning; M Dodson Michael; Rohit N Kulkarni
Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus.
Journal of pediatric endocrinology & metabolism : JPEM 2000;13 Suppl 6():1377-84.
1999: Rohit N Kulkarni; Jonathon Winnay; M Daniels; Jens C Brüning; S N Flier; Douglas Hanahan; C Ronald Kahn
Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.
The Journal of clinical investigation 1999;104(12):R69-75.
1999: Jens C Brüning; C R Kahn; Wilhelm Krone; Dirk Müller-Wieland
[Conditional mutagenesis--second generation knockout mice as models for internal diseases].
Medizinische Klinik (Munich, Germany : 1983) 1999;94(10):564-9.
1999: Rohit N Kulkarni; Jens C Brüning; Jonathon Winnay; C Postic; Mark Magnuson; C Ronald Kahn
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
Cell 1999;96(3):329-39.
1999: Stefan Lehr; Jorg Kotzka; Armin Herkner; E Klein; C Siethoff; Birgit Knebel; V Noelle; Jens C Brüning; Helmut W Klein; Helmut E Meyer; Wilhelm Krone; Dirk Müller-Wieland
Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.
Biochemistry 1999;38(1):151-9.
1998: Jens C Brüning; M Dodson Michael; Jonathon Winnay; Toshiaki Hayashi; D Hörsch; Domenico Accili; Laurie J Goodyear; C Ronald Kahn
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.
Molecular cell 1998;2(5):559-69.
1997: Jens C Brüning; Jonathon Winnay; Bentley Cheatham; C Ronald Kahn
Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.
Molecular and cellular biology 1997;17(3):1513-21.
1997: Jens C Brüning; Jonathon Winnay; Susan Bonner-Weir; S I Taylor; Domenico Accili; C Ronald Kahn
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles.
Cell 1997;88(4):561-72.
1994: E Araki; M A Lipes; Mary-Elizabeth Patti; Jens C Brüning; B Haag; R S Johnson; C Ronald Kahn
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.
Nature 1994;372(6502):186-90.