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Frank Brunkhorst

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Germany

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Intensive Care Units

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TOP 3
Christina Wacker; Frank M Brunkhorst; Anna Prkno; Peter Schlattmann
Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis.
S Hagel; M W Pletz; H Seifert; Frank M Brunkhorst; W V Kern
[Bacteremia and sepsis].
Dirk Schädler; Jens Scholz; Norbert Weiler; H Bogatsch; Frank M Brunkhorst; G Elke; Christoph Engel; Inéz Frerichs; Ralf Kuhlen; M Loeffler; Michael Quintel; K Reinhart; Rolf Rossaint
Ventilatory strategies in septic patients. Results from a nationwide observational trial.

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All Publications

2013: Christina Wacker; Frank M Brunkhorst; Anna Prkno; Peter Schlattmann
Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis.
The Lancet infectious diseases 2013;13(5):426-35.
2013: S Hagel; M W Pletz; H Seifert; Frank M Brunkhorst; W V Kern
[Bacteremia and sepsis].
Der Internist 2013;54(4):399-407.
2013: Dirk Schädler; Jens Scholz; Norbert Weiler; H Bogatsch; Frank M Brunkhorst; G Elke; Christoph Engel; Inéz Frerichs; Ralf Kuhlen; M Loeffler; Michael Quintel; K Reinhart; Rolf Rossaint
Ventilatory strategies in septic patients. Results from a nationwide observational trial.
Der Anaesthesist 2013;62(1):27-33.
2012: Frank M Brunkhorst; Markus W Büchler; Christoph Engel; Harald Fritz; Matthias Gründling; Ulrich Jaschinski; Stefan John; Michael Kiehntopf; Marin H Kollef; Evelyn Kuhnt; Markus Loeffler; Katrin Ludewig; Gernot Marx; Andreas Meier-Hellmann; Onnen Moerer; Axel Nierhaus; Michael Oppert; Christian Putensen; Maximilian Ragaller; Lorenz Reill; Konrad Reinhart; Reimer Riessen; Armin Seibel; Claudia Spies; Tobias Welte; Andreas Weyland; Friedhelm Bach; Frank Bloos; Holger Bogatsch
Effect of empirical treatment with moxifloxacin and meropenem vs meropenem on sepsis-related organ dysfunction in patients with severe sepsis: a randomized trial.
JAMA : the journal of the American Medical Association 2012;307(22):2390-9.
2011: Robert Hutagalung; Bjorn Kabisch; Kathrin Kobylka; Juliana Marques; Konrad Reinhart; Frank M Brunkhorst; Mohamed Zeidan; Yasser Sakr
The obesity paradox in surgical intensive care unit patients.
Intensive care medicine 2011;37(11):1793-9.
2011: Christiane S Hartog; Evelyn Kuhnt; Andreas Meier-Hellmann; Maximilian Ragaller; Konrad Reinhart; Tobias Welte; Frank M Brunkhorst; Christoph Engel
Are renal adverse effects of hydroxyethyl starches merely a consequence of their incorrect use?
Wiener klinische Wochenschrift 2011;123(5-6):145-55.
2011: Frank Bloos; Derek C Angus; Robert A Balk; Richard P Dellinger; Guillermo Gutierrez; Pierre-Francois Laterre; John C Marshall; Konrad Reinhart; Emanuel P Rivers; Jean-Louis Vincent; Frank M Brunkhorst
Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study.
Critical care (London, England) 2011;15(2):R88.
2010: Frank M Brunkhorst; P Gastmeier; W Kern; W Krüger; Konstantin Mayer; A Weimann; T Welte; C Putensen; Karl Werdan; Konrad Reinhart
[Prevention and follow-up care of sepsis. 1st revision of S2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V., DSG) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin, DIVI)].
Der Internist 2010;51(7):925-32.
2010: Mathias W Pletz; Frank Bloos; Olaf Burkhardt; Frank M Brunkhorst; Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Mark W Greer; Heino Stass; Tobias Welte
Pharmacokinetics of moxifloxacin in patients with severe sepsis or septic shock.
Intensive care medicine 2010;36(6):979-83.
2010: Petra Gastmeier; Frank M Brunkhorst; Martin Schrappe; W Kern; Christine Geffers
[How many nosocomial infections are avoidable?].
Deutsche medizinische Wochenschrift (1946) 2010;135(3):91-3.
2010: Frank M Brunkhorst
[Tight glucose control in intensive care patients--contra].
Deutsche medizinische Wochenschrift (1946) 2010;135(14):705.
2010: Konrad Reinhart; Christiane S Hartog; Frank M Brunkhorst
Hydroxyethyl starches: Plus ça change, plus c'est la même chose.
Anesthesiology 2010;112(3):756-7.
2010: Konrad Reinhart; Frank M Brunkhorst; H-G Bone; J Bardutzky; C-E Dempfle; H Forst; P Gastmeier; Herwig Gerlach; M Gründling; S John; W Kern; G Kreymann; W Krüger; P Kujath; G Marggraf; J Martin; Konstantin Mayer; Andreas Meier-Hellmann; M Oppert; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; H Seifert; C Spies; F Stüber; Norbert Weiler; A Weimann; Karl Werdan; T Welte
Prevention, diagnosis, therapy and follow-up care of sepsis: 1st revision of S-2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V. (DSG)) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin (DIVI)).
German medical science : GMS e-journal 2010;8():Doc14.
2009: Frank M Brunkhorst; Konrad Reinhart
[Diagnosis and causal treatment of sepsis].
Der Internist 2009;50(7):810-6.
2009: Frank M Brunkhorst; Konrad Reinhart
[Supportive and adjunctive sepsis therapy].
Der Internist 2009;50(7):817-24, 826-7.
2009: Ralf Claus; Clemens Bockmeyer; Ulrich Budde; Karim Kentouche; Maik Sossdorf; Thomas Hilberg; Reinhard Schneppenheim; Konrad Reinhart; Michael Bauer; Frank M Brunkhorst; Wolfgang Lösche
Variations in the ratio between von Willebrand factor and its cleaving protease during systemic inflammation and association with severity and prognosis of organ failure.
Thrombosis and haemostasis 2009;101(2):239-47.
2008: Frank M Brunkhorst
[Sepsismarker--what is useful?].
Deutsche medizinische Wochenschrift (1946) 2008;133(48):2512-5.
2008: Frank M Brunkhorst; Christoph Engel; Maximilian Ragaller; Tobias Welte; Rolf Rossaint; Herwig Gerlach; Konstantin Mayer; Stefan John; Frank Stuber; Norbert Weiler; Michael Oppert; Onnen Moerer; Holger Bogatsch; Konrad Reinhart; Markus Loeffler; Christiane Hartog
Practice and perception--a nationwide survey of therapy habits in sepsis.
Critical care medicine 2008;36(10):2719-25.
2008: Yasser Sakr; C Sponholz; F Tuche; Frank M Brunkhorst; Konrad Reinhart
The role of procalcitonin in febrile neutropenic patients: review of the literature.
Infection 2008;36(5):396-407.
2008: Konrad Reinhart; Frank M Brunkhorst; Christoph Engel; Frank Bloos; Andreas Meier-Hellmann; Maximilian Ragaller; Norbert Weiler; Onnen Moerer; Matthias Gruendling; Michael Oppert; Stefan Grond; Derk Olthoff; U Jaschinski; S John; Rolf Rossaint; Tobias Welte; M Schaefer; P Kern; E Kuhnt; Michael Kiehntopf; T Deufel; C Hartog; Herwig Gerlach; F Stüber; H-D Volk; Michael Quintel; Markus Loeffler
[Study protocol of the VISEP study. Response of the SepNet study group].
Der Anaesthesist 2008;57(7):723-8.
2008: Yasser Sakr; Ulricke Burgett; Flavio E Nacul; Konrad Reinhart; Frank M Brunkhorst
Lipopolysaccharide binding protein in a surgical intensive care unit: a marker of sepsis?
Critical care medicine 2008;36(7):2014-22.
2008: Gunnar Elke; Dirk Schädler; Christoph Engel; Holger Bogatsch; Inéz Frerichs; Maximilian Ragaller; Jens Scholz; Frank M Brunkhorst; Markus Loeffler; Konrad Reinhart; Norbert Weiler
Current practice in nutritional support and its association with mortality in septic patients--results from a national, prospective, multicenter study.
Critical care medicine 2008;36(6):1762-7.
2008: Frank M Brunkhorst; Konrad Reinhart
[Sepsis therapy: present guidelines and their application].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2008;79(4):306-14.
2008: Frank M Brunkhorst; Christoph Engel; Frank Bloos; Andreas Meier-Hellmann; Maximilian Ragaller; Norbert Weiler; Onnen Moerer; Matthias Gruendling; Michael Oppert; Stefan Grond; Derk Olthoff; Ulrich Jaschinski; Stefan John; Rolf Rossaint; Tobias Welte; Martin Schaefer; Peter Kern; Evelyn Kuhnt; Michael Kiehntopf; Christiane Hartog; Charles Natanson; Markus Loeffler; Konrad Reinhart
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
The New England journal of medicine 2008;358(2):125-39.
2008: Alvaro Rea-Neto; Nazah Cherif M Youssef; Fabio Tuche; Frank M Brunkhorst; V Marco Ranieri; Konrad Reinhart; Yasser Sakr
Diagnosis of ventilator-associated pneumonia: a systematic review of the literature.
Critical care (London, England) 2008;12(2):R56.
2008: Clemens Bockmeyer; Ralf Claus; Ulrich Budde; Karim Kentouche; Reinhard Schneppenheim; Wolfgang Lösche; Konrad Reinhart; Frank M Brunkhorst
Inflammation-associated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor.
Haematologica 2008;93(1):137-40.
2007: Yasser Sakr; Konrad Reinhart; Stefan Hagel; Michael Kientopf; Frank M Brunkhorst
Antithrombin levels, morbidity, and mortality in a surgical intensive care unit.
Anesthesia and analgesia 2007;105(3):715-23.
2007: Frank M Brunkhorst; Yasser Sakr; Stefan Hagel; Konrad Reinhart
Protein C concentrations correlate with organ dysfunction and predict outcome independent of the presence of sepsis.
Anesthesiology 2007;107(1):15-23.
2007: Frank M Brunkhorst; Konrad Reinhart
Intensive insulin therapy in the ICU: benefit versus harm?
Intensive care medicine 2007;33(7):1302.
2007: Yasser Sakr; Konrad Reinhart; Frank Bloos; Gernot Marx; Stefan Russwurm; Michael Bauer; Frank M Brunkhorst
Time course and relationship between plasma selenium concentrations, systemic inflammatory response, sepsis, and multiorgan failure.
British journal of anaesthesia 2007;98(6):775-84.
2007: Wolfram Doehner; Alexander C Bunck; Mathias Rauchhaus; Stephan von Haehling; Frank M Brunkhorst; Mariantonietta Cicoira; Carsten Tschope; Piotr Ponikowski; Ralf Claus; Stefan D Anker
Secretory sphingomyelinase is upregulated in chronic heart failure: a second messenger system of immune activation relates to body composition, muscular functional capacity, and peripheral blood flow.
European heart journal 2007;28(7):821-8.
2007: Christoph Engel; Frank M Brunkhorst; Hans-Georg Bone; Reinhard Brunkhorst; Herwig Gerlach; Stefan Grond; Matthias Gruendling; Guenter Huhle; Ulrich Jaschinski; Stefan John; Konstantin Mayer; Michael Oppert; Derk Olthoff; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; Frank Stuber; Norbert Weiler; Tobias Welte; Holger Bogatsch; Christiane Hartog; Markus Loeffler; Konrad Reinhart
Epidemiology of sepsis in Germany: results from a national prospective multicenter study.
Intensive care medicine 2007;33(4):606-18.
2006: Gernot Marx; Frank M Brunkhorst; Konrad Reinhart
[Intensive insulin therapy in critically ill patients--contra].
Deutsche medizinische Wochenschrift (1946) 2006;131(44):2481.
2006: K Reinhart; Frank M Brunkhorst; H-G Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; A Meier-Hellmann; C Peckelsen; C Putensen; F Stüber; M Quintel; Maximilian Ragaller; R Rossaint; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis].
Clinical research in cardiology : official journal of the German Cardiac Society 2006;95(8):429-54.
2006: Michael Bauer; Frank M Brunkhorst; T Welte; Herwig Gerlach; Konrad Reinhart
[Sepsis. Update on pathophysiology, diagnostics and therapy].
Der Anaesthesist 2006;55(8):835-45.
2006: Konrad Reinhart; Michael Meisner; Frank M Brunkhorst
Markers for sepsis diagnosis: what is useful?
Critical care clinics 2006;22(3):503-19, ix-x.
2006: Frank M Brunkhorst; Karl Werdan
[Intensive care medicine: after positive studies questions occur].
Deutsche medizinische Wochenschrift (1946) 2006;131(25-26):1441-4.
2006: Konrad Reinhart; Frank M Brunkhorst; H Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; Andreas Meier-Hellmann; C Peckelsen; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; F Stüber; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis: guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine].
Der Anaesthesist 2006;55 Suppl 1():43-56.
2006: S D Anker; M John; P U Pedersen; C Raguso; Mariantonietta Cicoira; E Dardai; A Laviano; P Ponikowski; Annemie M W J Schols; Heinrich Becker; M Böhm; Frank M Brunkhorst; Claus Vogelmeier
ESPEN Guidelines on Enteral Nutrition: Cardiology and pulmonology.
Clinical nutrition (Edinburgh, Scotland) 2006;25(2):311-8.
2006: Konrad Reinhart; Frank M Brunkhorst; H Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; Andreas Meier-Hellmann; C Peckelsen; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; F Stüber; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis. Guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine].
Der Internist 2006;47(4):356, 358-60, 362-8, passim.
2006: Frank M Brunkhorst; Hans Günther Wahl
Blood glucose measurements in the critically ill: more than just a blood draw.
Critical care (London, England) 2006;10(6):178.
2006: Christoph Sponholz; Yasser Sakr; Konrad Reinhart; Frank M Brunkhorst
Diagnostic value and prognostic implications of serum procalcitonin after cardiac surgery: a systematic review of the literature.
Critical care (London, England) 2006;10(5):R145.
2006: Frank M Brunkhorst
[Epidemiology, economy and practice -- results of the German study on prevalence by the competence network sepsis (SepNet)].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2006;41(1):43-4.
2005: V Tomic; Stefan Russwurm; Eva Möller; Ralf Claus; M Blaess; Frank M Brunkhorst; Mathias Bruegel; K Bode; Frank Bloos; Jens Wippermann; Thorsten Wahlers; Hans-Peter Deigner; J Thiery; Konrad Reinhart; Michael Bauer
Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting.
Circulation 2005;112(19):2912-20.
2005: Ralf Claus; Alexander C Bunck; Clemens Bockmeyer; Frank M Brunkhorst; Wolfgang Lösche; Ralf Kinscherf; Hans-Peter Deigner
Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1719-21.
2005: Thomas Hilberg; Hans-Peter Deigner; Eva Möller; Ralf Claus; Andriy Ruryk; Doreen Gläser; Julien Landre; Frank M Brunkhorst; Konrad Reinhart; Holger H W Gabriel; Stefan Russwurm
Transcription in response to physical stress--clues to the molecular mechanisms of exercise-induced asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1492-4.
2005: Frank M Brunkhorst; Frank Bloos; Reinhild Klein
Ramipril induced polyserositis with pericardial tamponade and pleural effusion.
International journal of cardiology 2005;102(2):355-6.
2002: Konrad Reinhart; Ole Bayer; Frank M Brunkhorst; Michael Meisner
Markers of endothelial damage in organ dysfunction and sepsis.
Critical care medicine 2002;30(5 Suppl):S302-12.
2002: Frank M Brunkhorst; Waheedullah Karzai; Konrad Reinhart
[Diagnostic approach to sepsis - state of the art].
Zentralblatt für Chirurgie 2002;127(3):165-73.
2002: Frank M Brunkhorst; B Al-Nawas; F Krummenauer; ZF Forycki; P M Shah
Procalcitonin, C-reactive protein and APACHE II score for risk evaluation in patients with severe pneumonia.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2002;8(2):93-100.
2000: Michael Meisner; Frank M Brunkhorst; H B Reith; Joachim Schmidt; H G Lestin; Konrad Reinhart
Clinical experiences with a new semi-quantitative solid phase immunoassay for rapid measurement of procalcitonin.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(10):989-95.
2000: Reinhard Brunkhorst; O K Eberhardt; Marion Haubitz; Frank M Brunkhorst
Procalcitonin for discrimination between activity of systemic autoimmune disease and systemic bacterial infection.
Intensive care medicine 2000;26 Suppl 2():S199-201.
1999: Frank M Brunkhorst; Andrew L Clark; ZF Forycki; S D Anker
Pyrexia, procalcitonin, immune activation and survival in cardiogenic shock: the potential importance of bacterial translocation.
International journal of cardiology 1999;72(1):3-10.
1999: Frank M Brunkhorst; OK Eberhard; Reinhard Brunkhorst
Discrimination of infectious and noninfectious causes of early acute respiratory distress syndrome by procalcitonin.
Critical care medicine 1999;27(10):2172-6.
1998: Frank M Brunkhorst; U Heinz; ZF Forycki
Kinetics of procalcitonin in iatrogenic sepsis.
Intensive care medicine 1998;24(8):888-9.
1998: Frank M Brunkhorst; OK Eberhard; Reinhard Brunkhorst
Early identification of biliary pancreatitis with procalcitonin.
The American journal of gastroenterology 1998;93(7):1191-2.
1998: OK Eberhard; I Langefeld; Ernst R Kuse; Frank M Brunkhorst; Volker Kliem; Hans J Schlitt; Rudolf Pichlmayr; Karl-Martin Koch; Reinhard Brunkhorst
Procalcitonin in the early phase after renal transplantation--will it add to diagnostic accuracy?
Clinical transplantation 1998;12(3):206-11.
1997: OK Eberhard; Marion Haubitz; Frank M Brunkhorst; Volker Kliem; Karl-Martin Koch; Reinhard Brunkhorst
Usefulness of procalcitonin for differentiation between activity of systemic autoimmune disease (systemic lupus erythematosus/systemic antineutrophil cytoplasmic antibody-associated vasculitis) and invasive bacterial infection.
Arthritis and rheumatism 1997;40(7):1250-6.