FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ilan Ifergan

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Disorders

Breast Neoplasms

Concepts & Ideas

Drug Dose Response Relationship

Co-author Network

Publications

TOP 3
Ilan Ifergan; Vicky Goler-Baron; Yehuda G Assaraf
Riboflavin concentration within ABCG2-rich extracellular vesicles is a novel marker for multidrug resistance in malignant cells.
Ilan Ifergan; Gerrit Jansen; Yehuda G Assaraf
The reduced folate carrier (RFC) is cytotoxic to cells under conditions of severe folate deprivation. RFC as a double edged sword in folate homeostasis.
Ilan Ifergan; Yehuda G Assaraf
Molecular mechanisms of adaptation to folate deficiency.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ilan Ifergan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2009: Ilan Ifergan; Vicky Goler-Baron; Yehuda G Assaraf
Riboflavin concentration within ABCG2-rich extracellular vesicles is a novel marker for multidrug resistance in malignant cells.
Biochemical and biophysical research communications 2009;380(1):5-10.
2008: Ilan Ifergan; Gerrit Jansen; Yehuda G Assaraf
The reduced folate carrier (RFC) is cytotoxic to cells under conditions of severe folate deprivation. RFC as a double edged sword in folate homeostasis.
The Journal of biological chemistry 2008;283(30):20687-95.
2008: Ilan Ifergan; Yehuda G Assaraf
Molecular mechanisms of adaptation to folate deficiency.
Vitamins and hormones 2008;79():99-143.
2007: Ruud Oerlemans; Jacqueline M Vink; B A C Dijkmans; Yehuda G Assaraf; Marjolein van Miltenburg; Joost van der Heijden; Ilan Ifergan; Willem F Lems; Rik J Scheper; G J L Kaspers; Jacqueline Cloos; Gerrit Jansen
Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis.
Annals of the rheumatic diseases 2007;66(10):1289-95.
2007: Eran Bram; Ilan Ifergan; Michal Grimberg; Krzysztof Lemke; Andrzej Skladanowski; Yehuda G Assaraf
C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells.
Biochemical pharmacology 2007;74(1):41-53.
2006: Eran Bram; Ilan Ifergan; Assaf Shafran; Bluma Berman; Gerrit Jansen; Yehuda G Assaraf
Mutant Gly482 and Thr482 ABCG2 mediate high-level resistance to lipophilic antifolates.
Cancer chemotherapy and pharmacology 2006;58(6):826-34.
2006: Yehuda G Assaraf; Ilan Ifergan; Wisam N Kadry; Ron Y Pinter
Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.
Journal of theoretical biology 2006;240(4):637-47.
2006: Yotam Kaufman; Ilan Ifergan; Lilah Rothem; Gerrit Jansen; Yehuda G Assaraf
Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss.
Blood 2006;107(8):3288-94.
2006: Ruud Oerlemans; Joost van der Heijden; Jacqueline M Vink; B A C Dijkmans; G J L Kaspers; Willem F Lems; George L Scheffer; Ilan Ifergan; Rik J Scheper; Jacqueline Cloos; Yehuda G Assaraf; Gerrit Jansen
Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids.
Arthritis and rheumatism 2006;54(2):557-68.
2005: Ilan Ifergan; George L Scheffer; Yehuda G Assaraf
Novel extracellular vesicles mediate an ABCG2-dependent anticancer drug sequestration and resistance.
Cancer research 2005;65(23):10952-8.
2005: Assaf Shafran; Ilan Ifergan; Eran Bram; Gerrit Jansen; Ietje Kathmann; Godefridus J Peters; Robert W Robey; Susan E Bates; Yehuda G Assaraf
ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates.
Cancer research 2005;65(18):8414-22.
2005: Ilan Ifergan; Gerrit Jansen; Yehuda G Assaraf
Cytoplasmic confinement of breast cancer resistance protein (BCRP/ABCG2) as a novel mechanism of adaptation to short-term folate deprivation.
Molecular pharmacology 2005;67(4):1349-59.
2004: Gerrit Jansen; Joost van der Heijden; Ruud Oerlemans; Willem F Lems; Ilan Ifergan; Rik J Scheper; Yehuda G Assaraf; B A C Dijkmans
Sulfasalazine is a potent inhibitor of the reduced folate carrier: implications for combination therapies with methotrexate in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(7):2130-9.
2004: Ilan Ifergan; Assaf Shafran; Gerrit Jansen; Jan Hendrik Hooijberg; George L Scheffer; Yehuda G Assaraf
Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis.
The Journal of biological chemistry 2004;279(24):25527-34.
2004: Yotam Kaufman; Stavit Drori; Peter Cole; Barton A. Kamen; Jenny Sirota; Ilan Ifergan; Myriam Weyl Ben Arush; Ronit Elhasid; Dvora Sahar; G J L Kaspers; Gerrit Jansen; Larry H Matherly; Gideon Rechavi; Amos Toren; Yehuda G Assaraf
Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
Cancer 2004;100(4):773-82.
2003: Ilan Ifergan; Issac Meller; Josephine Issakov; Yehuda G Assaraf
Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity.
Cancer 2003;98(9):1958-66.
2003: Yehuda G Assaraf; Lilah Rothem; Jan Hendrik Hooijberg; Michal Stark; Ilan Ifergan; Ietje Kathmann; B A C Dijkmans; Godefridus J Peters; Gerrit Jansen
Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.
The Journal of biological chemistry 2003;278(9):6680-6.
2002: Lilah Rothem; Ilan Ifergan; Yotam Kaufman; David G Priest; Gerrit Jansen; Yehuda G Assaraf
Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.
The Biochemical journal 2002;367(Pt 3):741-50.