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Tom Vree

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TOP 3
Karin P W Schoenmakers; Bart van den Bemt; jacques van limbeek; Tom B Vree; Nigel T M Jack; Rudolf Stienstra
Pharmacokinetics of 450 mg ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study.
Tom B Vree; Mathieu J M Gielen
Clinical pharmacology and the use of articaine for local and regional anaesthesia.
Anneleen Kuijsten; Ilja C W Arts; Tom B Vree; Peter C H Hollman
Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside.

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All Publications

2013: Karin P W Schoenmakers; Bart van den Bemt; jacques van limbeek; Tom B Vree; Nigel T M Jack; Rudolf Stienstra
Pharmacokinetics of 450 mg ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study.
British journal of clinical pharmacology 2013;75(5):1321-7.
2005: Tom B Vree; Mathieu J M Gielen
Clinical pharmacology and the use of articaine for local and regional anaesthesia.
Best practice & research. Clinical anaesthesiology 2005;19(2):293-308.
2005: Anneleen Kuijsten; Ilja C W Arts; Tom B Vree; Peter C H Hollman
Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside.
The Journal of nutrition 2005;135(4):795-801.
2004: Tom B Vree; Erik Dammers; R Valducci
Sex-related differences in the pharmacokinetics of isosorbide-5-mononitrate (60 mg) after repeated oral administration of two different original prolonged release formulations.
International journal of clinical pharmacology and therapeutics 2004;42(8):463-72.
2003: Tom B Vree; Erik Dammers; Ivan Ulc; Stefan Horkovics-Kovats; Miroslav Ryska
Lack of male-female differences in disposition and esterase hydrolysis of ramipril to ramiprilat in healthy volunteers after a single oral dose.
TheScientificWorldJournal 2003;3():1332-43.
2003: Tom B Vree; Erik Dammers; Ivan Ulc; Stefan Horkovics-Kovats; Miroslav Ryska; Ijsbrand Merkx
Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers:gut hydrolysis of lovastatin is twice that of simvastatin.
TheScientificWorldJournal 2003;3():1332-43.
2003: Tom B Vree; Erik Dammers; E Van Duuren
Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy dogs.
Journal of veterinary pharmacology and therapeutics 2003;26(3):165-71.
2003: Marc M Snoeck; Tom B Vree; Mathieu J M Gielen; A J Lagerwert
Steady state bupivacaine plasma concentrations and safety of a femoral "3-in-1" nerve block with bupivacaine in patients over 80 years of age.
International journal of clinical pharmacology and therapeutics 2003;41(3):107-13.
2003: Tom B Vree; Erik Dammers; Peter S Exler
Identical pattern of highly variable absorption of clavulanic acid from four different oral formulations of co-amoxiclav in healthy subjects.
The Journal of antimicrobial chemotherapy 2003;51(2):373-8.
2002: Tom B Vree; Erik Dammers; Eri van Duuren
Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy cats.
TheScientificWorldJournal 2002;2():1369-78.
2002: Marc A M Simon; Tom B Vree; Mathieu J M Gielen; L H D J Booij; Aart J Lagerwerf
Similar motor block effects and disposition kinetics between lidocaine and (+/-)mepivacaine in patients undergoing axillary brachial plexus block during day case surgery.
TheScientificWorldJournal 2002;2():1306-19.
2000: Tom B Vree; Erik Dammers; Peter S Exler; F Sörgel; S Bondesen; Robert A A Maes
Liver and gut mucosa acetylation of mesalazine in healthy volunteers.
International journal of clinical pharmacology and therapeutics 2000;38(11):514-22.
2000: L H D J Booij; Tom B Vree
Skeletal muscle relaxants: pharmacodynamics and pharmacokinetics in different patient groups.
International journal of clinical practice 2000;54(8):526-34.
2000: Tom B Vree; R T van Dongen; P M Koopman-Kimenai
Codeine analgesia is due to codeine-6-glucuronide, not morphine.
International journal of clinical practice 2000;54(6):395-8.
2000: Tom B Vree; Erik Dammers; Peter S Exler; Robert A A Maes
Mono- and biphasic plasma concentration-time curves of mesalazine from a 500 mg suppository in healthy male volunteers controlled by the time of defecation before dosing.
The Journal of pharmacy and pharmacology 2000;52(6):645-52.
2000: Margreet R Olthof; Peter C H Hollman; Tom B Vree; Martijn B Katan
Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans.
The Journal of nutrition 2000;130(5):1200-3.
1999: Marc A M Simon; Tom B Vree; Mathieu J M Gielen; L H D J Booij; Aart J Lagerwerf
Similar motor block effects with different disposition kinetics between lidocaine and (+ or -) articaine in patients undergoing axillary brachial plexus block during day case surgery.
International journal of clinical pharmacology and therapeutics 1999;37(12):598-607.
1999: Tom B Vree; L Maljers; N Van den Borg; N M Nibbering; CP Verwey-van Wissen; Aart J Lagerwerf; Robert A A Maes; PJ Jongen
High-performance liquid-chromatographic-atmospheric-pressure chemical-ionization ion-trap mass-spectrometric identification of isomeric C6-hydroxy and C20-hydroxy metabolites of methylprednisolone in the urine of patients receiving high-dose pulse therapy.
The Journal of pharmacy and pharmacology 1999;51(10):1155-66.
1999: Tom B Vree; Aart J Lagerwerf; CP Verwey-van Wissen; PJ Jongen
High-performance liquid chromatography analysis, preliminary pharmacokinetics, metabolism and renal excretion of methylprednisolone with its C6 and C20 hydroxy metabolites in multiple sclerosis patients receiving high-dose pulse therapy.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(2):337-48.
1999: Tom B Vree; J Waitzinger; A Hammermaier; S Radhofer-Welte
Absolute bioavailability, pharmacokinetics, renal and biliary clearance of distigmine after a single oral dose in comparison to i.v. administration of 14C-distigmine-bromide in healthy volunteers.
International journal of clinical pharmacology and therapeutics 1999;37(8):393-403.
1999: Tom B Vree; CP Verwey-van Wissen; Aart J Lagerwerf; A Swolfs; Robert A A Maes; Ronald D van Ooijen; O R van Eikema Hommes; PJ Jongen
Isolation and identification of the C6-hydroxy and C20-hydroxy metabolites and glucuronide conjugate of methylprednisolone by preparative high-performance liquid chromatography from urine of patients receiving high-dose pulse therapy.
Journal of chromatography. B, Biomedical sciences and applications 1999;726(1-2):157-68.
1999: Tom B Vree; A J van der Ven
Clinical consequences of the biphasic elimination kinetics for the diuretic effect of furosemide and its acyl glucuronide in humans.
The Journal of pharmacy and pharmacology 1999;51(3):239-48.
1999: Tom B Vree; Aart J Lagerwerf; C P Bleeker; P M de Grood
Direct high-performance liquid chromatography determination of propofol and its metabolite quinol with their glucuronide conjugates and preliminary pharmacokinetics in plasma and urine of man.
Journal of chromatography. B, Biomedical sciences and applications 1999;721(2):217-28.
1998: Marc A M Simon; Tom B Vree; Mathieu J M Gielen; L H D J Booij
Comparison of the effects and disposition kinetics of articaine and lidocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.
Pharmacy world & science : PWS 1998;20(2):88-92.
1998: Jacques J Driessen; Eric N Robertson; L H D J Booij; Tom B Vree
Accelerated recovery and disposition from rocuronium in an end-stage renal failure patient on chronic anticonvulsant therapy with sodium valproate and primidone.
British journal of anaesthesia 1998;80(3):386-8.
1998: Marc A M Simon; Tom B Vree; Mathieu J M Gielen; L H D J Booij; Aart J Lagerwerf
Comparison of the effects and disposition kinetics of lidocaine and (+/-)prilocaine in patients undergoing axillary brachial plexus block during day case surgery.
Clinical drug investigation 1998;16(3):241-50.
1998: Marc A M Simon; Mathieu J M Gielen; Tom B Vree; L H D J Booij
Disposition of lignocaine for intravenous regional anaesthesia during day-case surgery.
European journal of anaesthesiology 1998;15(1):32-7.
1997: Tom B Vree; M A Simon; Mathieu J M Gielen; L H D J Booij
Regional metabolism of articaine in 10 patients undergoing intravenous regional anaesthesia during day case surgery.
British journal of clinical pharmacology 1997;44(1):29-34.
1997: Marc A M Simon; Tom B Vree; Mathieu J M Gielen; L H D J Booij
Comparison of the disposition kinetics of lidocaine and (+/-)prilocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.
Journal of clinical pharmacy and therapeutics 1997;22(2):141-6.
1997: Tom B Vree; G E Van Oss; Mathieu J M Gielen; L H D J Booij
Epidural metabolism of articaine to its metabolite articainic acid in five patients after epidural administration of 600 mg articaine.
The Journal of pharmacy and pharmacology 1997;49(2):158-63.
1997: Marc A M Simon; Mathieu J M Gielen; N Alberink; Tom B Vree; Jan Van Egmond
Intravenous regional anesthesia with 0.5% articaine, 0.5% lidocaine, or 0.5% prilocaine. A double-blind randomized clinical study.
Regional anesthesia 1997;22(1):29-34.
1996: A J van der Ven; Tom B Vree; Peter P Koopmans; J W van der Meer
Adverse reactions to co-trimoxazole in HIV infection: a reappraisal of the glutathione-hydroxylamine hypothesis.
The Journal of antimicrobial chemotherapy 1996;37 Suppl B():55-60.
1996: A J van der Ven; A Riegr; A Branten; R Reiman; Tom B Vree; Peter P Koopmans; J W van der Meer
Cutaneous reactions to trimethoprim-sulphametrole in AIDS patients treated for Pneumocystis carinii pneumonia.
AIDS (London, England) 1996;10(3):341-2.
1995: Tom B Vree; M Van Den Biggelaar-Martea; C P Verwey-Van Wissen
Frusemide and its acyl glucuronide show a short and long phase in elimination kinetics and pharmacodynamic effect in man.
The Journal of pharmacy and pharmacology 1995;47(11):964-9.
1995: Tom B Vree; E Schoondermark-van de Ven; C P Verwey-van Wissen; A M Bars; A Swolfs; P M van Galen; H Amatdjais-Groenen
Isolation, identification and determination of sulfadiazine and its hydroxy metabolites and conjugates from man and rhesus monkey by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1995;670(1):111-23.
1995: P M Koopman-Kimenai; Tom B Vree; L H D J Booij; R Dirksen
The bioavailability of intramuscularly administered nicomorphine (Vilan) with its metabolites and their glucuronide conjugates in surgical patients.
International journal of clinical pharmacology and therapeutics 1995;33(8):442-8.
1995: P M Koopman-Kimenai; Tom B Vree; L H D J Booij; M A Hasenbos
Pharmacokinetics of epidurally administered nicomorphine with its metabolites and glucuronide conjugates in patients undergoing pulmonary surgery during combined epidural local anaesthetic block and general anaesthesia.
Biopharmaceutics & drug disposition 1995;16(6):507-20.
1995: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen
Probenecid inhibits the renal clearance of frusemide and its acyl glucuronide.
British journal of clinical pharmacology 1995;39(6):692-5.
1995: A J van der Ven; Tom B Vree; E W van Ewijk-Beneken Kolmer; Peter P Koopmans; J W van der Meer
Urinary recovery and kinetics of sulphamethoxazole and its metabolites in HIV-seropositive patients and healthy volunteers after a single oral dose of sulphamethoxazole.
British journal of clinical pharmacology 1995;39(6):621-5.
1995: Peter P Koopmans; A J van der Ven; Tom B Vree; J W van der Meer
Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: allergic or toxic?
AIDS (London, England) 1995;9(3):217-22.
1995: P F Baaijens; Mathieu J M Gielen; Tom B Vree; B J Crul; H J Jessen
Bupivacaine toxicity secondary to continuous cervical epidural infusion. Case report.
Regional anesthesia 1995;20(2):163-8.
1994: P M Koopman-Kimenai; Tom B Vree; L H D J Booij; R Dirksen
Rectal administration of nicomorphine in patients improves biological availability of morphine and its glucuronide conjugates.
Pharmacy world & science : PWS 1994;16(6):248-53.
1994: Tom B Vree; E W Van Ewijk-Beneken Kolmer; C P Verwey-Van Wissen; Yechiel A Hekster
Effect of urinary pH on the pharmacokinetics of salicylic acid, with its glycine and glucuronide conjugates in human.
International journal of clinical pharmacology and therapeutics 1994;32(10):550-8.
1994: Tom B Vree; A J van der Ven; C P Verwey-van Wissen; E W van Ewijk-Beneken Kolmer; A E Swolfs; P M van Galen; H Amatdjais-Groenen
Isolation, identification and determination of sulfamethoxazole and its known metabolites in human plasma and urine by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1994;658(2):327-40.
1994: A J van der Ven; M A Mantel; Tom B Vree; Peter P Koopmans; J W van der Meer
Formation and elimination of sulphamethoxazole hydroxylamine after oral administration of sulphamethoxazole.
British journal of clinical pharmacology 1994;38(2):147-50.
1994: A J van der Ven; Peter P Koopmans; Tom B Vree; J W van der Meer
Drug intolerance in HIV disease.
The Journal of antimicrobial chemotherapy 1994;34(1):1-5.
1994: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen
Determination of furosemide with its acyl glucuronide in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis with fluorescence detection. Preliminary pharmacokinetics and effect of probenecid.
Journal of chromatography. B, Biomedical applications 1994;655(1):53-62.
1994: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen; E W van Ewijk-Beneken Kolmer
Probenecid inhibits the glucuronidation of indomethacin and O-desmethylindomethacin in humans. A pilot experiment.
Pharmacy world & science : PWS 1994;16(1):22-6.
1994: Tom B Vree; E W van Ewijk-Beneken Kolmer; C P Verwey-van Wissen; Yechiel A Hekster
Direct gradient reversed-phase high-performance liquid chromatographic determination of salicylic acid, with the corresponding glycine and glucuronide conjugates in human plasma and urine.
Journal of chromatography 1994;652(2):161-70.
1994: Tom B Vree; U M Hoeben; E W van Ewijk-Beneken Kolmer; J F Nouws
Glucuronidation of flumequine by the turtle Pseudemys scripta elegans.
Journal of veterinary pharmacology and therapeutics 1994;17(1):80-2.
1994: Tom B Vree; M L Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen; J F Nouws
Glucuronidation of naproxen by the turtle Pseudemys scripta elegans.
Journal of veterinary pharmacology and therapeutics 1994;17(1):74-6.
1993: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen; M L Vree; P J Guelen
The effects of cimetidine, ranitidine and famotidine on the single-dose pharmacokinetics of naproxen and its metabolites in humans.
International journal of clinical pharmacology, therapy, and toxicology 1993;31(12):597-601.
1993: Tom B Vree; E W Van Ewijk-Beneken Kolmer; Eveline W Wuis; Yechiel A Hekster; M M Broekman
Interindividual variation in the capacity-limited renal glucuronidation of probenecid by humans.
Pharmacy world & science : PWS 1993;15(5):197-202.
1993: Tom B Vree; M Van den Biggelaar-Martea; E W Van Ewijk-Beneken Kolmer; Yechiel A Hekster
Probenecid inhibits the renal clearance and renal glucuronidation of nalidixic acid. A pilot experiment.
Pharmacy world & science : PWS 1993;15(4):165-70.
1993: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen; J B Vree; P J Guelen
Pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl glucuronides in humans.
Biopharmaceutics & drug disposition 1993;14(6):491-502.
1993: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen
Determination of indomethacin, its metabolites and their glucuronides in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis. Preliminary pharmacokinetics and effect of probenecid.
Journal of chromatography 1993;616(2):271-82.
1993: S P Boom; A C Wouterse; Tom B Vree; C A Van Ginneken; Frans G M Russel
Renal tubular excretion of the N4-acetyl metabolites of sulphasomidine and sulphadimethoxine in the dog.
The Journal of pharmacy and pharmacology 1993;45(7):614-7.
1993: Tom B Vree; M van den Biggelaar-Martea; E W van Ewijk-Beneken Kolmer; Yechiel A Hekster
Direct gradient reversed-phase HPLC analysis and preliminary pharmacokinetics of nalidixic acid, 7-hydroxymethylnalidixic acid, 7-carboxynalidixic acid, and their corresponding glucuronide conjugates in humans.
Pharmacy world & science : PWS 1993;15(3):98-104.
1993: Tom B Vree; M Van Den Biggelaar-Martea; C P Verwey-Van Wissen; M L Vree; P J Guelen
The pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl glucuronides in humans. Effect of cimetidine.
British journal of clinical pharmacology 1993;35(5):467-72.
1993: P M Koopman-Kimenai; Tom B Vree; L H D J Booij; R Dirksen; G M Nijhuis
Pharmacokinetics of intravenously administered nicomorphine and its metabolites in man.
European journal of anaesthesiology 1993;10(2):125-32.
1992: Tom B Vree; Yechiel A Hekster; P G Anderson
Contribution of the human kidney to the metabolic clearance of drugs.
The Annals of pharmacotherapy 1992;26(11):1421-8.
1992: Tom B Vree; E W Van Ewijk-Beneken Kolmer; Eveline W Wuis; Yechiel A Hekster
Capacity-limited renal glucuronidation of probenecid by humans. A pilot Vmax-finding study.
Pharmaceutisch weekblad. Scientific edition 1992;14(5):325-31.
1992: P J Guelen; T J Janssen; T C De Witte; Tom B Vree; K Benson
Bioavailability of lithium from lithium citrate syrup versus conventional lithium carbonate tablets.
Biopharmaceutics & drug disposition 1992;13(7):503-11.
1992: Tom B Vree; E W van Ewijk-Beneken Kolmer; J F Nouws
Direct-gradient high-performance liquid chromatographic analysis and preliminary pharmacokinetics of flumequine and flumequine acyl glucuronide in humans: effect of probenecid.
Journal of chromatography 1992;579(1):131-41.
1992: Tom B Vree; C P Verwey-van Wissen
Pharmacokinetics and metabolism of codeine in humans.
Biopharmaceutics & drug disposition 1992;13(6):445-60.
1992: Tom B Vree; M van den Biggelaar-Martea; C P Verwey-van Wissen
Determination of naproxen and its metabolite O-desmethylnaproxen with their acyl glucuronides in human plasma and urine by means of direct gradient high-performance liquid chromatography.
Journal of chromatography 1992;578(2):239-49.
1992: Tom B Vree; E M Beumer; A J Lagerwerf; Marc A M Simon; Mathieu J M Gielen
Clinical pharmacokinetics of R(+)- and S(-)-mepivacaine after high doses of racemic mepivacaine with epinephrine in the combined psoas compartment/sciatic nerve block.
Anesthesia and analgesia 1992;75(1):75-80.
1992: Tom B Vree; E W Beneken Kolmer
Direct measurement of probenecid and its glucuronide conjugate by means of high pressure liquid chromatography in plasma and urine of humans.
Pharmaceutisch weekblad. Scientific edition 1992;14(3):83-7.
1992: A J van der Ven; Peter P Koopmans; Tom B Vree; J W van der Meer
[Frequent side effects of cotrimoxazole in persons infected with HIV, possibly due to metabolites of sulfamethoxazole].
Nederlands tijdschrift voor geneeskunde 1992;136(2):61-3.
1992: Tom B Vree; M van den Biggelaar-Martea; A Peeters; B P Imbimbo
High-performance liquid chromatography and preliminary pharmacokinetics of rufloxacin and its metabolites, N-desmethylrufloxacin and rufloxacinsulfoxide, in urine of rhesus monkey Macaca mulatta.
Journal of chromatography 1992;573(1):168-72.
1992: Tom B Vree; W J Beneken Kolmer; Yechiel A Hekster; M Shimoda; M Ono; T Miura
Pharmacokinetics and acetylation of sulfa-2-monomethoxine in humans.
Biopharmaceutics & drug disposition 1992;13(1):55-68.
1992: Tom B Vree; M van den Biggelaar-Martea; B P Imbimbo
High performance liquid chromatography and preliminary pharmacokinetics of rufloxacin and its metabolites N-desmethylrufloxacin and rufloxacinsulfoxide in plasma and urine of humans.
European journal of drug metabolism and pharmacokinetics 1992;17(1):45-9.
1991: Tom B Vree; E W Beneken Kolmer; Yechiel A Hekster
Pharmacokinetics, N1-glucuronidation and N4-acetylation of sulfamethomidine in humans.
Pharmaceutisch weekblad. Scientific edition 1991;13(5):198-206.
1991: A J Lagerwerf; L E Vanlinthout; Tom B Vree
Rapid determination of succinylcholine in human plasma by high-performance liquid chromatography with fluorescence detection.
Journal of chromatography 1991;570(2):390-5.
1991: C P Verwey-van Wissen; P M Koopman-Kimenai; Tom B Vree
Direct determination of codeine, norcodeine, morphine and normorphine with their corresponding O-glucuronide conjugates by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography 1991;570(2):309-20.
1991: Tom B Vree; E W Beneken Kolmer; A Peeters
Comparison of the metabolism of four sulphonamides between humans and pigs.
The Veterinary quarterly 1991;13(4):236-40.
1991: Tom B Vree; J B Vree; E W Beneken Kolmer; Yechiel A Hekster
Novel oxidative pathways of sulphapyridine and sulphadiazine by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1991;13(4):218-24.
1991: A J van der Ven; Peter P Koopmans; Tom B Vree; Jos W M van der Meer
Adverse reactions to co-trimoxazole in HIV infection.
Lancet 1991;338(8764):431-3.
1991: Tom B Vree; M L Vree; E W Beneken Kolmer; Yechiel A Hekster; M Shimoda; M Ono; T Miura
O-Dealkylation and N4-acetylation of sulpha-2-monomethoxine by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1991;13(3):176-80.
1991: J F Nouws; Tom B Vree; M Degen; D Mevius
Pharmacokinetics of a sulphamethoxazole/trimethoprim formulation in pigs after intravenous administration.
The Veterinary quarterly 1991;13(3):148-54.
1991: P M Koopman-Kimenai; Tom B Vree; M A Hasenbos; E W Weber; C P Verweij-Van Wissen; L H D J Booij
Pharmacokinetics of nicomorphine and its metabolites in man after epidural administration.
Pharmaceutisch weekblad. Scientific edition 1991;13(3):142-7.
1991: Tom B Vree; A M Baars; Eveline W Wuis
Direct high pressure liquid chromatographic analysis and preliminary pharmacokinetics of enantiomers of oxazepam and temazepam with their corresponding glucuronide conjugates.
Pharmaceutisch weekblad. Scientific edition 1991;13(2):83-90.
1991: Tom B Vree; M L Vree; N Benneken Kolmer; Yechiel A Hekster; M Shimoda
N2-glucuronidation and N4-acetylation of sulphaphenazole by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1991;13(1):60-4.
1991: J F Nouws; Tom B Vree; M Degen; D Mevius
Pharmacokinetics of sulphamethoxazole in calves and cows.
The Veterinary quarterly 1991;13(1):10-5.
1991: P M Koopman-Kimenai; Tom B Vree; L H D J Booij; R Dirksen; G M Nijhuis
Pharmacokinetics of intramuscular nicomorphine and its metabolites in man.
European journal of clinical pharmacology 1991;41(4):375-8.
1991: Jacques J Driessen; Tom B Vree; P J Guelen
The effects of acute changes in renal function on the pharmacokinetics of midazolam during long-term infusion in ICU patients.
Acta anaesthesiologica Belgica 1991;42(3):149-55.
1990: Tom B Vree; M Martea; L M Lewin
High-performance liquid chromatography of sulfapyridine and its acetyl and glucuronide metabolites in rat and human urine.
Journal of chromatography 1990;534():214-22.
1990: Tom B Vree; E W Beneken Kolmer; Yechiel A Hekster
High pressure liquid chromatographic analysis and preliminary pharmacokinetics of sulfaphenazole and its N2-glucuronide and N4-acetyl metabolites in plasma and urine of man.
Pharmaceutisch weekblad. Scientific edition 1990;12(6):243-6.
1990: Tom B Vree; Yechiel A Hekster
Pharmacokinetics and tissue concentrations of cefuroxime.
Pharmaceutisch weekblad. Scientific edition 1990;12(6A):262-6; discussion 267.
1990: G J Wijnands; J H Cornel; M Martea; Tom B Vree
The effect of multiple-dose oral lomefloxacin on theophylline metabolism in man.
Chest 1990;98(6):1440-4.
1990: W J Wijnands; J F Trooster; P C Teunissen; H A Cats; Tom B Vree
Ciprofloxacin does not impair the elimination of diazepam in humans.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):954-7.
1990: Tom B Vree; E W Beneken Kolmer; Yechiel A Hekster; M Shimoda; M Ono; T Miura
Pharmacokinetics, N1-glucuronidation, and N4-acetylation of sulfa-6-monomethoxine in humans.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):852-8.
1990: P J Guelen; T J Janssen; M H Lam; Tom B Vree; P S Exler
Comparative bioavailability study of two brands of prazosin-containing tablets in healthy volunteers.
Pharmaceutisch weekblad. Scientific edition 1990;12(5):184-7.
1990: Marc A M Simon; Mathieu J M Gielen; A J Lagerwerf; Tom B Vree
Plasma concentrations after high doses of mepivacaine with epinephrine in the combined psoas compartment/sciatic nerve block.
Regional anesthesia 1990;15(5):256-60.
1990: D Landsdorp; Tom B Vree; T J Janssen; P J Guelen
Pharmacokinetics of rectal diclofenac and its hydroxy metabolites in man.
International journal of clinical pharmacology, therapy, and toxicology 1990;28(7):298-302.
1990: D Lansdorp; T J Janssen; P J Guelen; Tom B Vree
High-performance liquid chromatographic method for the determination of diclofenac and its hydroxy metabolites in human plasma and urine.
Journal of chromatography 1990;528(2):487-94.
1990: Eveline W Wuis; M J Dirks; Tom B Vree; E Van der Kleijn
Pharmacokinetics of baclofen in spastic patients receiving multiple oral doses.
Pharmaceutisch weekblad. Scientific edition 1990;12(2):71-4.
1990: Tom B Vree; E W Beneken Kolmer; M Martea; R Bosch; Yechiel A Hekster; M Shimoda
Pharmacokinetics, N1-glucuronidation and N4-acetylation of sulfadimethoxine in man.
Pharmaceutisch weekblad. Scientific edition 1990;12(2):51-9.
1990: Tom B Vree; R P Steegers-Theunissen; A M Baars; Yechiel A Hekster
Direct high-performance liquid chromatographic analysis of p-hydroxyphenyl-phenylhydantoin glucuronide, the final metabolite of phenytoin, in human serum and urine.
Journal of chromatography 1990;526(2):581-9.
1990: Eveline W Wuis; M G Janssen; Tom B Vree; E van der Kleijn
Determination of a dantrolene metabolite, 5-(p-nitrophenyl)-2-furoic acid, in plasma and urine by high-performance liquid chromatography.
Journal of chromatography 1990;526(2):575-80.
1990: M Shimoda; Tom B Vree; E W Beneken Kolmer; T H Arts
The role of plasma protein binding on the metabolism and renal excretion of sulphadimethoxine and its metabolite N4-acetylsulphadimethoxine in pigs.
The Veterinary quarterly 1990;12(2):87-97.
1990: Tom B Vree; E W Kolmer; M Martea; R Bosch; M Shimoda
High-performance liquid chromatography of sulphadimethoxine and its N1-glucuronide, N4-acetyl and N4-acetyl-N1-glucuronide metabolites in human plasma and urine.
Journal of chromatography 1990;526(1):119-28.
1990: Zbigniew Zylicz; D J Th Wagener; M Garzotto; Tom B Vree; E van der Kleijn; L A van den Broek; H C Ottenheijm
Pharmacokinetics of the antitumor antibiotic n-pentyl-sparsomycin in beagle dogs.
Investigational new drugs 1990;8(1):25-32.
1990: Tom B Vree; A Klimowicz; J B Vree; M Shimoda
O-dealkylation and acetylation of sulphamethomidine by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1990;12(1):60-3.
1990: Eveline W Wuis; Tom B Vree; E Van Der Kleijn
Pharmacokinetics of intravenously administered dantrolene and its 5-hydroxy metabolite in dogs.
International journal of clinical pharmacology research 1990;10(4):203-10.
1989: G J Wijnands; Tom B Vree; T J Janssen; P J Guelen
Drug-drug interactions affecting fluoroquinolones.
The American journal of medicine 1989;87(6C):47S-51S.
1989: Tom B Vree; J B Vree; P A De Jonge; M J Plaum; C P Verwey; Yechiel A Hekster; M Shimoda; J F Nouws
Lack of oxidative pathways in the metabolism of sulphisomidine by the turtle Pseudemys scripta elegans.
Journal of veterinary pharmacology and therapeutics 1989;12(4):459-62.
1989: Tom B Vree; M Shimoda; Jacques J Driessen; P J Guelen; T J Janssen; E F Termond; R van Dalen; J C Hafkenscheid; M S Dirksen
Decreased plasma albumin concentration results in increased volume of distribution and decreased elimination of midazolam in intensive care patients.
Clinical pharmacology and therapeutics 1989;46(5):537-44.
1989: Tom B Vree; M L Vree; E W Beneken Kolmer; M E Ross; Yechiel A Hekster; M Shimoda; J F Nouws
o-Dealkylation and acetylation of sulfamethomidine by the snail Cepaea hortensis.
Journal of veterinary pharmacology and therapeutics 1989;12(3):344-7.
1989: Yechiel A Hekster; Tom B Vree; M W Tijhuis; E F Termond
The pharmacokinetics of sulfapyridine and its N4-acetyl-, and hydroxy metabolites in man.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):597-9.
1989: Tom B Vree; J B Vree; N Beneken Kolmer; Yechiel A Hekster; M Shimoda; J F Nouws; T Yoshioka; K Hoji
Oxidation and O-dealkylation of sulphamonomethoxine by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1989;11(3):186-90.
1989: Tom B Vree; J B Vree; N Beneken Kolmer; Yechiel A Hekster; M Shimoda; J F Nouws; T Yoshioka; K Hoji
O-demethylation and N4-acetylation of sulphadimethoxine by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1989;11(3):138-43.
1989: M Shimoda; E Kokue; T Hayama; Tom B Vree
Effect of albumin distribution. A simulation analysis of the effect of altered albumin distribution on the apparent volume of distribution and apparent elimination rate constant of drugs.
Pharmaceutisch weekblad. Scientific edition 1989;11(3):87-91.
1989: J F Nouws; D Mevius; Tom B Vree; M Degen
Pharmacokinetics and renal clearance of sulphadimidine, sulphamerazine and sulphadiazine and their N4-acetyl and hydroxy metabolites in pigs.
The Veterinary quarterly 1989;11(2):78-86.
1989: Tom B Vree; J B Vree; E B Kolmer; Yechiel A Hekster; J F Nouws; M Shimoda
N-oxidation, O-demethylation, and excretion of trimethoprim by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1989;11(2):125-8.
1989: Tom B Vree; M L Vree; E W Beneken Kolmer; Yechiel A Hekster; M Shimoda; J F Nouws; T Yoshioka; K Hoji
Oxidation and acetylation of sulfamonomethoxine by the snail Cepaea hortensis.
Nihon juigaku zasshi. The Japanese journal of veterinary science 1989;51(2):369-72.
1989: Tom B Vree; M L Vree; E W Beneken Kolmer; Yechiel A Hekster; M Shimoda; J F Nouws; T Yoshioka; K Hoji
O-demethylation and N4-acetylation of sulfadimethoxine by the snail Cepaea hortensis.
Nihon juigaku zasshi. The Japanese journal of veterinary science 1989;51(2):364-8.
1989: J F Nouws; Tom B Vree; D Mevius; M Degen
Pharmacokinetics, metabolism and renal clearance of sulphatroxazole in calves and cows.
Journal of veterinary pharmacology and therapeutics 1989;12(1):50-7.
1989: Jacques J Driessen; M S Dirksen; J M Rutten; F Santman; Jan Van Egmond; Tom B Vree
Continuous infusion of midazolam during anaesthesia and postoperative sedation after maxillofacial surgery.
Acta anaesthesiologica Scandinavica 1989;33(2):116-21.
1989: Eveline W Wuis; M J Dirks; E F Termond; Tom B Vree; E Van der Kleijn
Plasma and urinary excretion kinetics of oral baclofen in healthy subjects.
European journal of clinical pharmacology 1989;37(2):181-4.
1989: Eveline W Wuis; M J Dirks; E F Termond; Tom B Vree; E Van der Kleijn
Comparison of the pharmacokinetics of intravenously administered rac-baclofen and its (-)-(R)- and (+)-(S)-enantiomers in dogs.
International journal of clinical pharmacology research 1989;9(4):239-46.
1989: G E van Oss; Tom B Vree; A M Baars; E F Termond; L H D J Booij
Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration.
European journal of anaesthesiology 1989;6(1):49-56.
1988: G E Van Oss; Tom B Vree; A M Baars; E F Termond; L H D J Booij
Clinical effects and pharmacokinetics of articainic acid in one volunteer after intravenous administration.
Pharmaceutisch weekblad. Scientific edition 1988;10(6):284-6.
1988: W J Wijnands; T J Janssen; P J Guelen; Tom B Vree; T M De Witte
The influence of ofloxacin and enoxacin on the metabolic pathways of theophylline in healthy volunteers. A pilot study.
Pharmaceutisch weekblad. Scientific edition 1988;10(6):272-6.
1988: Tom B Vree; M Martea; R G Tiggeler; Yechiel A Hekster; J C Hafkenscheid
Pharmacokinetics of theophylline and its metabolites in a patient undergoing continuous ambulatory peritoneal dialysis.
Clinical pharmacokinetics 1988;15(6):390-5.
1988: Zbigniew Zylicz; D J Th Wagener; M Garzotto; Tom B Vree; E van der Kleijn; L A van den Broek; H C Ottenheijm
Preclinical pharmacokinetics of the antitumor antibiotic deshydroxy-sparsomycin in beagle dogs.
Anticancer research 1988;8(6):1381-5.
1988: Tom B Vree; W J Wijnands; A M Baars; Yechiel A Hekster
Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation.
Pharmaceutisch weekblad. Scientific edition 1988;10(5):193-9.
1988: Tom B Vree; J B Vree; I M Baars; Yechiel A Hekster; J F Nouws
N-oxidation, N-demethylation, and excretion of pefloxacin by the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1988;10(4):277-80.
1988: W J Wijnands; Tom B Vree; A M Baars; J C Hafkenscheid; B E Kohler; Cees van Herwaarden
The penetration of ofloxacin into lung tissue.
The Journal of antimicrobial chemotherapy 1988;22 Suppl C():85-9.
1988: W J Wijnands; Tom B Vree
Interaction between the fluoroquinolones and the bronchodilator theophylline.
The Journal of antimicrobial chemotherapy 1988;22 Suppl C():109-14.
1988: Tom B Vree; L Riemens; P M Koopman-Kimenai
High-performance liquid chromatography of xanthines. Effects of N-methyl and C-8 hydroxyl substitution on the retention times.
Journal of chromatography 1988;428(2):311-9.
1988: J F Nouws; D Mevius; Tom B Vree; M Baakman; M Degen
Pharmacokinetics, metabolism, and renal clearance of sulfadiazine, sulfamerazine, and sulfamethazine and of their N4-acetyl and hydroxy metabolites in calves and cows.
American journal of veterinary research 1988;49(7):1059-65.
1988: P J Guelen; T J Janssen; M M Brueren; Tom B Vree; G J Lipperts
The pharmacokinetic profile of naproxen suppository in man.
International journal of clinical pharmacology, therapy, and toxicology 1988;26(4):190-3.
1988: Tom B Vree; A M Baars; G E van Oss; L H D J Booij
High-performance liquid chromatography and preliminary pharmacokinetics of articaine and its 2-carboxy metabolite in human serum and urine.
Journal of chromatography 1988;424(2):440-4.
1988: W J Wijnands; Tom B Vree; A M Baars; Cees van Herwaarden
Pharmacokinetics of enoxacin and its penetration into bronchial secretions and lung tissue.
The Journal of antimicrobial chemotherapy 1988;21 Suppl B():67-77.
1988: Tom B Vree; J B Vree; A M Baars; J F Nouws; Yechiel A Hekster
Hydroxylation and oxidation of nalidixic acid in the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1988;10(1):67-9.
1988: T J Janssen; P J Guelen; Tom B Vree; M H Botterblom; R Valducci
Bioavailability of ambroxol sustained release preparations. Part II: Single and multiple oral dose studies in man.
Arzneimittel-Forschung 1988;38(1):95-7.
1988: P J Guelen; Tom B Vree; D de Vos; K Lamers
Comparative bioavailability and kinetics of folinic acid in the pharmaceutical formulations of Rescuvolin and Ledervorin in healthy volunteers.
Biopharmaceutics & drug disposition 1988;9(1):31-9.
1987: W J Wijnands; Tom B Vree; A M Baars; Cees van Herwaarden
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Pharmaceutisch weekblad. Scientific edition 1987;9 Suppl():S72-5.
1987: M S Dirksen; Tom B Vree; Jacques J Driessen
Clinical pharmacokinetics of long-term infusion of midazolam in critically ill patients--preliminary results.
Anaesthesia and intensive care 1987;15(4):440-4.
1987: M H Botterblom; T J Janssen; P J Guelen; Tom B Vree
Rapid and sensitive determination of ambroxol in human plasma and urine by high-performance liquid chromatography.
Journal of chromatography 1987;421(1):211-5.
1987: Tom B Vree; J B Vree; Yechiel A Hekster; J F Nouws
Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the turtle Pseudemys scripta elegans.
The Veterinary quarterly 1987;9(4):381-4.
1987: Tom B Vree; M L Vree; J F Nouws
Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the snail Cepaea hortensis.
The Veterinary quarterly 1987;9(4):378-81.
1987: Eveline W Wuis; L E van Beijsterveldt; R J Dirks; Tom B Vree; E van der Kleyn
Rapid simultaneous determination of baclofen and its gamma-hydroxy metabolite in urine by high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography 1987;420(1):212-6.
1987: Tom B Vree; A M Baars; P M de Grood
High-performance liquid chromatographic determination and preliminary pharmacokinetics of propofol and its metabolites in human plasma and urine.
Journal of chromatography 1987;417(2):458-64.
1987: J F Nouws; Tom B Vree; M M Aerts; M Degen; F Driessens
Some pharmacokinetic data about furaltadone and nitrofurazone administered orally to preruminant calves.
The Veterinary quarterly 1987;9(3):208-14.
1987: Jacques J Driessen; Tom B Vree; F Van de Pol; J F Crul
Pharmacokinetics of diazepam and four 3-hydroxy-benzodiazepines in the cat.
European journal of drug metabolism and pharmacokinetics 1987;12(3):219-24.
1987: Eveline W Wuis; E W Beneken Kolmer; L E van Beijsterveldt; R C Burgers; Tom B Vree; E van der Kleyn
Enantioselective high-performance liquid chromatographic determination of baclofen after derivatization with a chiral adduct of o-phthaldialdehyde.
Journal of chromatography 1987;415(2):419-22.
1987: Zbigniew Zylicz; D J Th Wagener; P Fernandez del Moral; H van Rennes; J M Wessels; B Winograd; E van der Kleijn; Tom B Vree; U van Haelst; L A van den Broek
Pharmacokinetics and toxicology of sparsomycin in beagle dogs.
Cancer chemotherapy and pharmacology 1987;20(2):115-24.
1987: W J Wijnands; Tom B Vree; A M Baars; Cees van Herwaarden
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline.
Drugs 1987;34 Suppl 1():159-69.
1986: Jacques J Driessen; J F Crul; Tom B Vree; Jan Van Egmond; L H D J Booij
Benzodiazepines and neuromuscular blocking drugs in patients.
Acta anaesthesiologica Scandinavica 1986;30(8):642-6.
1986: D J Mevius; J F Nouws; H J Breukink; Tom B Vree; F Driessens; R Verkaik
Comparative pharmacokinetics, bioavailability and renal clearance of five parenteral oxytetracycline-20% formulations in dairy cows.
The Veterinary quarterly 1986;8(4):285-94.
1986: D J Mevius; L Vellenga; H J Breukink; J F Nouws; Tom B Vree; F Driessens
Pharmacokinetics and renal clearance of oxytetracycline in piglets following intravenous and oral administration.
The Veterinary quarterly 1986;8(4):274-84.
1986: M S Dirksen; Tom B Vree; Jacques J Driessen
Midazolam in the intensive care unit.
Drug intelligence & clinical pharmacy 1986;20(10):805-6.
1986: G L Scheepstra; Tom B Vree; J F Crul; F van de Pol; J Reekers-Ketting
Convulsive effects and pharmacokinetics of laudanosine in the rat.
European journal of anaesthesiology 1986;3(5):371-83.
1986: J F Nouws; Tom B Vree; J Holtkamp; M Baakman; F Driessens; P J Guelen
Pharmacokinetic, residue and irritation aspects of chloramphenicol sodium succinate and a chloramphenicol base formulation following intramuscular administration to ruminants.
The Veterinary quarterly 1986;8(3):224-32.
1986: Eveline W Wuis; J J Driessen; J Evers; Tom B Vree; E van der Kleyn
Dantrolene plasma and urine concentrations after oral pretreatment for malignant hyperthermia: report of a case.
European journal of anaesthesiology 1986;3(3):219-23.
1986: Tom B Vree; Yechiel A Hekster; M W Tijhuis; E F Termond; J F Nouws
Pharmacokinetics, metabolism and renal excretion of sulfatroxazole and its 5-hydroxy- and N4-acetyl-metabolites in man.
Biopharmaceutics & drug disposition 1986;7(3):239-52.
1986: J F Nouws; Tom B Vree; M Baakman; F Driessens; L Vellenga; D J Mevius
Pharmacokinetics, renal clearance, tissue distribution, and residue aspects of sulphadimidine and its N4-acetyl metabolite in pigs.
The Veterinary quarterly 1986;8(2):123-35.
1986: J F Nouws; Tom B Vree; M Baakman; F Driessens; H J Breukink; D Mevius
Age and dosage dependency in the plasma disposition and the renal clearance of sulfamethazine and its N4-acetyl and hydroxy metabolites in calves and cows.
American journal of veterinary research 1986;47(3):642-9.
1986: Tom B Vree; W J Wijnands; P J Guelen; A M Baars; Yechiel A Hekster
Pharmacokinetics: metabolism and renal excretion of quinolones in man.
Pharmaceutisch weekblad. Scientific edition 1986;8(1):29-34.
1986: Tom B Vree; T J Janssen; Yechiel A Hekster; E F Termond; A C van de Dries; W J Wijnands
Clinical pharmacokinetics of carbamazepine and its epoxy and hydroxy metabolites in humans after an overdose.
Therapeutic drug monitoring 1986;8(3):297-304.
1986: B Winograd; R J Lippens; M J Oosterbaan; M J Dirks; Tom B Vree; E van der Kleijn
Renal excretion and pharmacokinetics of methotrexate and 7-hydroxy-methotrexate following a 24-h high dose infusion of methotrexate in children.
European journal of clinical pharmacology 1986;30(2):231-8.
1986: R van Dalen; Tom B Vree; A M Baars; E Termond
Dosage adjustment for ceftazidime in patients with impaired renal function.
European journal of clinical pharmacology 1986;30(5):597-605.
1985: Jacques J Driessen; Tom B Vree; Jan Van Egmond; L H D J Booij; J F Crul
Interaction of midazolam with two non-depolarizing neuromuscular blocking drugs in the rat in vivo sciatic nerve-tibialis anterior muscle preparation.
British journal of anaesthesia 1985;57(11):1089-94.
1985: Tom B Vree; A M Baars; W J Wijnands
High-performance liquid chromatography and preliminary pharmacokinetics of enoxacin and its 4-oxo metabolite in human plasma, urine and saliva.
Journal of chromatography 1985;343(2):449-54.
1985: J F Nouws; Tom B Vree; M Baakman; F Driessens; A Smulders; J Holtkamp
Disposition of sulfadimidine and its N4-acetyl and hydroxy metabolites in horse plasma.
Journal of veterinary pharmacology and therapeutics 1985;8(3):303-11.
1985: E F Termond; B Zonnenberg; B Winograd; M J Oosterbaan; E Van der Kleijn; Tom B Vree
Comparison of linear and tapered intravenous infusion of methotrexate in oncochemotherapy. A theoretical approach.
Pharmaceutisch weekblad. Scientific edition 1985;7(4):158-62.
1985: J F Nouws; Tom B Vree; H J Breukink; M Baakman; F Driessens; A Smulders
Dose dependent disposition of sulphadimidine and of its N4-acetyl and hydroxy metabolites in plasma and milk of dairy cows.
The Veterinary quarterly 1985;7(3):177-86.
1985: Jacques J Driessen; Jan Van Egmond; Tom B Vree; L H Booij; J F Crul
The in vitro effects of benzodiazepines on the rat diaphragm. Structure-activity relationships.
Canadian journal of physiology and pharmacology 1985;63(5):444-8.
1985: Eveline W Wuis; R J Dirks; Tom B Vree; E van der Kleyn
High-performance liquid chromatographic analysis of baclofen in plasma and urine of man after precolumn extraction and derivatization with o-phthaldialdehyde.
Journal of chromatography 1985;337(2):341-50.
1985: Jacques J Driessen; Tom B Vree; Jan Van Egmond; L H D J Booij; J F Crul
Interaction of some benzodiazepines and their solvents with vecuronium in the in vivo rat sciatic nerve-tibialis anterior muscle preparation.
Archives internationales de pharmacodynamie et de thérapie 1985;273(2):277-88.
1985: J F Nouws; F Driessens; A Smulders; Tom B Vree
An improved bioassay for the qualitative detection of sulphonamide and dapsone residues.
The Veterinary quarterly 1985;7(1):76-8.
1984: Jacques J Driessen; Tom B Vree; Jan Van Egmond; L H D J Booij; J F Crul
In vitro interaction of diazepam and oxazepam with pancuronium and suxamethonium.
British journal of anaesthesia 1984;56(10):1131-8.
1984: Tom B Vree; Y A Hekster; M J Oosterbaan; E F Termond
Some pitfalls in selecting descriptive pharmacokinetic models.
Drug intelligence & clinical pharmacy 1984;18(9):708-13.
1984: Tom B Vree; Yechiel A Hekster; M W Tijhuis; M Baakman; M J Oosterbaan; E F Termond
Effects of methoxy groups in the NI-substituent of sulfonamides on the pathways of elimination in man. The acetylation-deacetylation equilibrium and mechanisms of renal excretion of sulfisomidine, sulfamethomidine and sulfadimethoxine.
Pharmaceutisch weekblad. Scientific edition 1984;6(4):150-6.
1984: Jacques J Driessen; Tom B Vree; L H Booij; F M van der Pol; J F Crul
Effect of some benzodiazepines on peripheral neuromuscular function in the rat in-vitro hemidiaphragm preparation.
The Journal of pharmacy and pharmacology 1984;36(4):244-7.
1984: M J Oosterbaan; R J Dirks; Tom B Vree; E van der Kleijn
Rapid quantitative determination of seven anthracyclines and their hydroxy metabolites in body fluids.
Journal of chromatography 1984;306():323-32.
1983: Jacques J Driessen; L H D J Booij; J F Crul; Tom B Vree
[Comparative study of thiopental and midazolam for induction of anesthesia].
Der Anaesthesist 1983;32(10):478-82.
1983: Tom B Vree; C A Hekster; M Baakman; T Janssen; M Oosterbaan; E Termond; M Tijhuis
Pharmacokinetics, acetylation-deacetylation, renal clearance, and protein binding of sulphamerazine, N4-acetylsulphamerazine, and N4-trideuteroacetylsulphamerazine in 'fast' and 'slow' acetylators.
Biopharmaceutics & drug disposition 1983;4(3):271-91.
1983: Tom B Vree; Yechiel A Hekster; M W Tijhuis; M Baakman; T J Janssen; E F Termond
The effect of the molecular structure of closely related N1-substituents of sulfonamides on the pathways of elimination in man. The acetylation-deacetylation equilibrium and renal clearance related to the structure of sulfadiazine, sulfamerazine and sulfadimidine.
Pharmaceutisch weekblad. Scientific edition 1983;5(2):49-56.
1983: J F Nouws; Tom B Vree; M Baakman; M Tijhuis
Effect of age on the acetylation and deacetylation reactions of sulphadimidine and N4-acetylsulphadimidine in calves.
Journal of veterinary pharmacology and therapeutics 1983;6(1):13-22.
1983: Tom B Vree; M W Tijhuis; M Baakman; C A Hekster
Analysis of N4-trideuteroacetylsulphamerazine and its metabolites sulphamerazine and N4-acetylsulphamerazine in man by means of high-performance liquid chromatography and mass spectrometry.
Biomedical mass spectrometry 1983;10(3):114-9.
1983: J F Nouws; Tom B Vree; M Tijhuis; M Baakman
The acetylation-deacetylation equilibrium of sulfadimidine in ruminant calves.
The Veterinary quarterly 1983;5(1):41-8.
1982: Eveline W Wuis; A C Grutters; Tom B Vree; E van der Kleyn
Simultaneous determination of dantrolene and its metabolites, 5-hydroxydantrolene and nitro-reduced acetylated dantrolene (F 490), in plasma and urine of man and dog by high-performance liquid chromatography.
Journal of chromatography 1982;231(2):401-9.
1982: L H Booij; Tom B Vree; F Van de Pol; J F Crul
Pharmacodynamics of vecuronium and pancuronium in cats with and without ligated renal pedicles.
Acta anaesthesiologica Belgica 1982;33(3):157-65.
1981: Y A Hekster; Tom B Vree; J E Damsma; W T Friesen
Pharmacokinetics of sulphametrole and its metabolite N4-acetylsulphametrole in man.
The Journal of antimicrobial chemotherapy 1981;8(2):133-44.
1981: Tom B Vree; Y A Hekster; J C Hafkenscheid; R van Dalen; W T Friesen
The influence of urine flow on renal clearance of creatinine in patients with normal and impaired kidney function.
Drug intelligence & clinical pharmacy 1981;15(3):194-8.
1981: Tom B Vree; Y A Hekster; J E Damsma; M Tijhuis; W T Friesen
Pharmacokinetics and mechanism of renal excretion of short acting sulphonamides and N4-acetylsulphonamide derivatives in man. Structural requirements of sulphonamides for active tubular secretion.
European journal of clinical pharmacology 1981;20(4):283-92.
1981: Tom B Vree; Y A Hekster; J E Damsma; R van Dalen; J C Hafkenscheid; W T Friesen
Renal excretion of sulphamethoxazole and its metabolite N4-acetylsulphamethoxazole in patients with impaired kidney function.
Therapeutic drug monitoring 1981;3(2):129-35.
1981: Jacques J Driessen; L H D J Booij; Tom B Vree; J F Crul
Midazolam as a sedative on regional anesthesia. Preliminary results.
Arzneimittel-Forschung 1981;31(12a):2245-7.
1980: P J Guelen; A M Baars; Tom B Vree; A J Nijkerk; J M Vermeer
Rapid and sensitive determination of chlorthalidone in blood, plasma and urine of man using high-performance liquid chromatography.
Journal of chromatography 1980;181(3-4):497-503.