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peter van haastert

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Dictyostelium

Chemicals & Drugs

Physiology

Concepts & Ideas

Kinetics

Anatomy

Cell Membrane

Genes & Molecular Sequences

Amino Acid Sequence

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Co-Publications
Name
14
Bosgraaf, Leonard
14
Snaar-Jagalska, Ewa
13
Roelofs, Jeroen
11
Schaap, Pauline
11
Devreotes, Peter
8
Kortholt, Arjan
8
Kuwayama, H
8
van Dijken, Peter
8
Veltman, Douwe
8
Visser, Antonie
8
van Lookeren Campagne, Michiel
7
Postma, Marten
6
Linskens, Maarten
6
Loovers, Harriët
6
Engel, Ruchira

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Publications

TOP 3
Veltman Douwe M; Keizer-Gunnik Ineke; Van Haastert Peter J M
Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum.
Veltman Douwe M; van Haastert Peter J M
The role of cGMP and the rear of the cell in Dictyostelium chemotaxis and cell streaming.
Kortholt Arjan; King Jason S; Keizer-Gunnink Ineke; Harwood Adrian J; Van Haastert Peter J M
Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.

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All Publications

2008: Veltman Douwe M; Keizer-Gunnik Ineke; Van Haastert Peter J M
Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum.
The Journal of cell biology 2008;180(4):747-53.
2008: Veltman Douwe M; van Haastert Peter J M
The role of cGMP and the rear of the cell in Dictyostelium chemotaxis and cell streaming.
Journal of cell science 2008;121(Pt 1):120-7.
2007: Kortholt Arjan; King Jason S; Keizer-Gunnink Ineke; Harwood Adrian J; Van Haastert Peter J M
Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.
Molecular biology of the cell 2007;18(12):4772-9.
2007: van Haastert Peter J M; Postma Marten
Biased random walk by stochastic fluctuations of chemoattractant-receptor interactions at the lower limit of detection.
Biophysical journal 2007;93(5):1787-96.
2007: Van Haastert Peter J M; Veltman Douwe M
Chemotaxis: navigating by multiple signaling pathways.
Science's STKE : signal transduction knowledge environment 2007;2007(396):pe40.
2007: van Haastert Peter J M; Keizer-Gunnink Ineke; Kortholt Arjan
Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis.
The Journal of cell biology 2007;177(5):809-16.
2007: Keizer-Gunnink Ineke; Kortholt Arjan; Van Haastert Peter J M
Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling.
The Journal of cell biology 2007;177(4):579-85.
2007: Kae Helmut; Kortholt Arjan; Rehmann Holger; Insall Robert H; Van Haastert Peter J M; Spiegelman George B; Weeks Gerald
Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.
EMBO reports 2007;8(5):477-82.
2007: Loovers Harriët M; Kortholt Arjan; de Groote Hendrie; Whitty Leslie; Nussbaum Robert L; van Haastert Peter J M
Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4.
Traffic (Copenhagen, Denmark) 2007;8(5):618-28.
2007: Bader Sonya; Kortholt Arjan; Van Haastert Peter J M
Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.
The Biochemical journal 2007;402(1):153-61.
2006: Bosgraaf Leonard; van Haastert Peter J M
The regulation of myosin II in Dictyostelium.
European journal of cell biology 2006;85(9-10):969-79.
2006: Veltman Douwe M; Van Haastert Peter J M
Guanylyl cyclase protein and cGMP product independently control front and back of chemotaxing Dictyostelium cells.
Molecular biology of the cell 2006;17(9):3921-9.
2006: Kortholt Arjan; Rehmann Holger; Kae Helmut; Bosgraaf Leonard; Keizer-Gunnink Ineke; Weeks Gerald; Wittinghofer Alfred; Van Haastert Peter J M
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum.
The Journal of biological chemistry 2006;281(33):23367-76.
2006: Bader Sonya; Kortholt Arjan; Snippe Helena; Van Haastert Peter J M
DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.
The Journal of biological chemistry 2006;281(29):20018-26.
2006: Goldberg Jonathan M; Wolpin Eric S; Bosgraaf Leonard; Clarkson Bryan K; Van Haastert Peter J M; Smith Janet L
Myosin light chain kinase A is activated by cGMP-dependent and cGMP-independent pathways.
FEBS letters 2006;580(8):2059-64.
2006: Loovers Harriët M; Postma Marten; Keizer-Gunnink Ineke; Huang Yi Elaine; Devreotes Peter N; van Haastert Peter J M
Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase.
Molecular biology of the cell 2006;17(4):1503-13.
2006: Engel Ruchira; Van Haastert Peter J M; Visser Antonie J W G
Spectral characterization of Dictyostelium autofluorescence.
Microscopy research and technique 2006;69(3):168-74.
2006: Van Haastert Peter J M
Analysis of signal transduction: formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro.
Methods in molecular biology (Clifton, N.J.) 2006;346():369-92.
2005: Bukharova Tanya; Weijer Gertrud; Bosgraaf Leonard; Dormann Dirk; van Haastert Peter J; Weijer Cornelis J
Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development.
Journal of cell science 2005;118(Pt 18):4295-310.
2005: Knol Jaco C; Engel Ruchira; Blaauw Mieke; Visser Antonie J W G; van Haastert Peter J M
The phosducin-like protein PhLP1 is essential for G{beta}{gamma} dimer formation in Dictyostelium discoideum.
Molecular and cellular biology 2005;25(18):8393-400.
2005: Bosgraaf Leonard; Waijer Arjen; Engel Ruchira; Visser Antonie J W G; Wessels Deborah; Soll David; van Haastert Peter J M
RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.
Journal of cell science 2005;118(Pt 9):1899-910.
2005: Veltman Douwe M; Roelofs Jeroen; Engel Ruchira; Visser Antonie J W G; Van Haastert Peter J M
Activation of soluble guanylyl cyclase at the leading edge during Dictyostelium chemotaxis.
Molecular biology of the cell 2005;16(2):976-83.
2004: Lu Yinghua; Knol Jaco C; Linskens Maarten H K; Friehs Karl; van Haastert Peter J M; Flaschel Erwin
Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand.
Applied microbiology and biotechnology 2004;65(5):547-52.
2004: Van Haastert Peter J M; Devreotes Peter N
Chemotaxis: signalling the way forward.
Nature reviews. Molecular cell biology 2004;5(8):626-34.
2004: Postma Marten; Roelofs Jeroen; Goedhart Joachim; Loovers Harriët M; Visser Antonie J W G; Van Haastert Peter J M
Sensitization of Dictyostelium chemotaxis by phosphoinositide-3-kinase-mediated self-organizing signalling patches.
Journal of cell science 2004;117(Pt 14):2925-35.
2004: Lu Yinghua; Knol Jaco C; Linskens Maarten H K; Friehs Karl; Van Haastert Peter J M; Flaschel Erwin
Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium.
Journal of biotechnology 2004;108(3):243-51.
2004: Ruchira; Hink Mark A; Bosgraaf Leonard; van Haastert Peter J M; Visser Antonie J W G
Pleckstrin homology domain diffusion in Dictyostelium cytoplasm studied using fluorescence correlation spectroscopy.
The Journal of biological chemistry 2004;279(11):10013-9.
2004: Postma Marten; Bosgraaf Leonard; Loovers Harriët M; Van Haastert Peter J M
Chemotaxis: signalling modules join hands at front and tail.
EMBO reports 2004;5(1):35-40.
2004: Veltman Douwe M; Bosgraaf Leonard; Van Haastert Peter J M
Unusual Guanylyl Cyclases and cGMP Signaling in Dictyostelium discoideum.
Vitamins and hormones 2004;69():95-115.
2003: Bosgraaf Leonard; Van Haastert Peter J M
Roc, a Ras/GTPase domain in complex proteins.
Biochimica et biophysica acta 2003;1643(1-3):5-10.
2003: Postma Marten; Roelofs Jeroen; Goedhart Joachim; Gadella Theodorus W J; Visser Antonie J W G; Van Haastert Peter J M
Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia.
Molecular biology of the cell 2003;14(12):5019-27.
2003: Veltman Douwe M; De Boer Jan Sietse; Van Haastert Peter J M
Chemoattractant-stimulated calcium influx in Dictyostelium discoideum does not depend on cGMP.
Biochimica et biophysica acta 2003;1623(2-3):129-34.
2003: Blaauw Mieke; Knol Jaco C; Kortholt Arjan; Roelofs Jeroen; Ruchira; Postma Marten; Visser Antonie J W G; van Haastert Peter J M
Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins.
The EMBO journal 2003;22(19):5047-57.
2003: Veltman Douwe; Van Haastert Peter J M
Regulation of Dictyostelium guanylyl cyclases.
Protist 2003;154(1):33-42.
2003: Roelofs Jeroen; Smith Janet L; Van Haastert Peter J M
cGMP signalling: different ways to create a pathway.
Trends in genetics : TIG 2003;19(3):132-4.
2003: Loovers Harriet M; Veenstra Kees; Snippe Helena; Pesesse Xavier; Erneux Christophe; van Haastert Peter J M
A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum.
The Journal of biological chemistry 2003;278(8):5652-8.
2002: Roelofs Jeroen; Van Haastert Peter J M
Deducing the origin of soluble adenylyl cyclase, a gene lost in multiple lineages.
Molecular biology and evolution 2002;19(12):2239-46.
2002: Bosgraaf Leonard; Russcher Henk; Snippe Helena; Bader Sonya; Wind Joyce; Van Haastert Peter J M
Identification and characterization of two unusual cGMP-stimulated phoshodiesterases in dictyostelium.
Molecular biology of the cell 2002;13(11):3878-89.
2002: Bosgraaf Leonard; Russcher Henk; Smith Janet L; Wessels Deborah; Soll David R; Van Haastert Peter J M
A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium.
The EMBO journal 2002;21(17):4560-70.
2002: Goldberg Jonathan M; Bosgraaf Leonard; Van Haastert Peter J M; Smith Janet L
Identification of four candidate cGMP targets in Dictyostelium.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6749-54.
2002: Roelofs Jeroen; Van Haastert Peter J M
Characterization of two unusual guanylyl cyclases from dictyostelium.
The Journal of biological chemistry 2002;277(11):9167-74.
2002: Bosgraaf Leonard; Van Haastert Peter J M
A model for cGMP signal transduction in Dictyostelium in perspective of 25 years of cGMP research.
Journal of muscle research and cell motility 2002;23(7-8):781-91.
2001: Roelofs J; Loovers H M; Van Haastert P J
GTPgammaS regulation of a 12-transmembrane guanylyl cyclase is retained after mutation to an adenylyl cyclase.
The Journal of biological chemistry 2001;276(44):40740-5.
2001: Potma E O; de Boeij W P; Bosgraaf L; Roelofs J; van Haastert P J; Wiersma D A
Reduced protein diffusion rate by cytoskeleton in vegetative and polarized dictyostelium cells.
Biophysical journal 2001;81(4):2010-9.
2001: Postma M; Van Haastert P J
A diffusion-translocation model for gradient sensing by chemotactic cells.
Biophysical journal 2001;81(3):1314-23.
2001: Roelofs J; Meima M; Schaap P; Van Haastert P J
The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase.
The EMBO journal 2001;20(16):4341-8.
2001: Roelofs J; Van Haastert P J
Genes lost during evolution.
Nature 2001;411(6841):1013-4.
2001: Roelofs J; Snippe H; Kleineidam R G; Van Haastert P J
Guanylate cyclase in Dictyostelium discoideum with the topology of mammalian adenylate cyclase.
The Biochemical journal 2001;354(Pt 3):697-706.
2001: Potma E; de Boeij W P; van Haastert P J; Wiersma D A
Real-time visualization of intracellular hydrodynamics in single living cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1577-82.
2001: Kuwayama H; Snippe H; Derks M; Roelofs J; Van Haastert P J
Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium.
The Biochemical journal 2001;353(Pt 3):635-44.
2001: Van Dijken P; Van Haastert P J
Phospholipase Cdelta regulates germination of Dictyostelium spores.
BMC cell biology 2001;2():25.
2000: Blaauw M; Linskens M H; van Haastert P J
Efficient control of gene expression by a tetracycline-dependent transactivator in single Dictyostelium discoideum cells.
Gene 2000;252(1-2):71-82.
2000: Vervoort E B; van Ravestein A; van Peij N N; Heikoop J C; van Haastert P J; Verheijden G F; Linskens M H
Optimizing heterologous expression in dictyostelium: importance of 5' codon adaptation.
Nucleic acids research 2000;28(10):2069-74.
1999: Linskens M H; Grootenhuis P D; Blaauw M; Huisman-de Winkel B; Van Ravestein A; Van Haastert P J; Heikoop J C
Random mutagenesis and screening of complex glycoproteins: expression of human gonadotropins in Dictyostelium discoideum.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(6):639-45.
1998: Heikoop J C; Grootenhuis P D; Blaauw M; Veldema J S; Van Haastert P J; Linskens M H
Expression of a bioactive, single-chain choriogonadotropin in Dictyostelium discoideum.
European journal of biochemistry / FEBS 1998;256(2):359-63.
1998: Otsuka H; Van Haastert P J
A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.
Genes & development 1998;12(11):1738-48.
1998: Kuwayama H; van Haastert P J
cGMP potentiates receptor-stimulated Ca2+ influx in Dictyostelium discoideum.
Biochimica et biophysica acta 1998;1402(1):102-8.
1998: Kuwayama H; Van Haastert P J
Chemotactic and osmotic signals share a cGMP transduction pathway in Dictyostelium discoideum.
FEBS letters 1998;424(3):248-52.
1997: Kim J Y; Soede R D; Schaap P; Valkema R; Borleis J A; Van Haastert P J; Devreotes P N; Hereld D
Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses.
The Journal of biological chemistry 1997;272(43):27313-8.
1997: van Haastert P J; van Dijken P
Biochemistry and genetics of inositol phosphate metabolism in Dictyostelium.
FEBS letters 1997;410(1):39-43.
1997: van Haastert P J; Kuwayama H
cGMP as second messenger during Dictyostelium chemotaxis.
FEBS letters 1997;410(1):25-8.
1997: Van Dijken P; Bergsma J C; Van Haastert P J
Phospholipase-C-independent inositol 1,4,5-trisphosphate formation in Dictyostelium cells. Activation of a plasma-membrane-bound phosphatase by receptor-stimulated Ca2+ influx.
European journal of biochemistry / FEBS 1997;244(1):113-9.
1996: Van Haastert P J; Bishop J D; Gomer R H
The cell density factor CMF regulates the chemoattractant receptor cAR1 in Dictyostelium.
The Journal of cell biology 1996;134(6):1543-9.
1996: Kuwayama H; Van Haastert P J
Regulation of guanylyl cyclase by a cGMP-binding protein during chemotaxis in Dictyostelium discoideum.
The Journal of biological chemistry 1996;271(39):23718-24.
1996: Van Dijken P; Bergsma J C; Hiemstra H S; De Vries B; Van Der Kaay J; Van Haastert P J
Dictyostelium discoideum contains three inositol monophosphatase activities with different substrate specificities and sensitivities to lithium.
The Biochemical journal 1996;314 ( Pt 2)():491-5.
1996: Kuwayama H; Ecke M; Gerisch G; Van Haastert P J
Protection against osmotic stress by cGMP-mediated myosin phosphorylation.
Science (New York, N.Y.) 1996;271(5246):207-9.
1995: Van der Kaay J; Wesseling J; Van Haastert P J
Nucleus-associated phosphorylation of Ins(1,4,5)P3 to InsP6 in Dictyostelium.
The Biochemical journal 1995;312 ( Pt 3)():911-7.
1995: Van der Kaay J; Van Haastert P J
Stereospecificity of inositol hexakisphosphate dephosphorylation by Paramecium phytase.
The Biochemical journal 1995;312 ( Pt 3)():907-10.
1995: Van Haastert P J
Transduction of the chemotactic cAMP signal across the plasma membrane of Dictyostelium cells.
Experientia 1995;51(12):1144-54.
1995: Van Dijken P; de Haas J R; Craxton A; Erneux C; Shears S B; Van Haastert P J
A novel, phospholipase C-independent pathway of inositol 1,4,5-trisphosphate formation in Dictyostelium and rat liver.
The Journal of biological chemistry 1995;270(50):29724-31.
1995: Drayer A L; Meima M E; Derks M W; Tuik R; van Haastert P J
Mutation of an EF-hand Ca(2+)-binding motif in phospholipase C of Dictyostelium discoideum: inhibition of activity but no effect on Ca(2+)-dependence.
The Biochemical journal 1995;311 ( Pt 2)():505-10.
1995: Kuwayama H; Viel G T; Ishida S; Van Haastert P J
Aberrant cGMP-binding activity in non-chemotactic Dictyostelium discoideum mutants.
Biochimica et biophysica acta 1995;1268(2):214-20.
1995: Wu L; Valkema R; Van Haastert P J; Devreotes P N
The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium.
The Journal of cell biology 1995;129(6):1667-75.
1995: Yuen I S; Jain R; Bishop J D; Lindsey D F; Deery W J; Van Haastert P J; Gomer R H
A density-sensing factor regulates signal transduction in Dictyostelium.
The Journal of cell biology 1995;129(5):1251-62.
1995: Van Dijken P; Lammers A A; Van Haastert P J
In Dictyostelium discoideum inositol 1,3,4,5-tetrakisphosphate is dephosphorylated by a 3-phosphatase and a 1-phosphatase.
The Biochemical journal 1995;308 ( Pt 1)():127-30.
1995: Van der Kaay J; Van Haastert P J
Desalting inositolpolyphosphates by dialysis.
Analytical biochemistry 1995;225(1):183-5.
1994: Van Dijken P; Lammers A A; Ozaki S; Potter B V; Erneux C; Van Haastert P J
Phosphorylation of inositol 1,4,5-trisphosphate analogues by 3-kinase and dephosphorylation of inositol 1,3,4,5-tetrakisphosphate analogues by 5-phosphatase.
European journal of biochemistry / FEBS 1994;226(2):561-6.
1994: Drayer A L; van Haastert P J
Transmembrane signalling in eukaryotes: a comparison between higher and lower eukaryotes.
Plant molecular biology 1994;26(5):1239-70.
1994: Van Haastert P J
Intracellular adenosine 3',5'-phosphate formation is essential for down-regulation of surface adenosine 3',5'-phosphate receptors in Dictyostelium.
The Biochemical journal 1994;303 ( Pt 2)():539-45.
1994: Valkema R; Van Haastert P J
A model for cAMP-mediated cGMP response in Dictyostelium discoideum.
Molecular biology of the cell 1994;5(5):575-85.
1994: Drayer A L; Van der Kaay J; Mayr G W; Van Haastert P J
Role of phospholipase C in Dictyostelium: formation of inositol 1,4,5-trisphosphate and normal development in cells lacking phospholipase C activity.
The EMBO journal 1994;13(7):1601-9.
1994: Bominaar A A; Van Haastert P J
Phospholipase C in Dictyostelium discoideum. Identification of stimulatory and inhibitory surface receptors and G-proteins.
The Biochemical journal 1994;297 ( Pt 1)():189-93.
1994: Bominaar A A; Kesbeke F; Van Haastert P J
Phospholipase C in Dictyostelium discoideum. Cyclic AMP surface receptor and G-protein-regulated activity in vitro.
The Biochemical journal 1994;297 ( Pt 1)():181-7.
1994: Snaar-Jagalska B E; Van Haastert P J
G-protein assays in Dictyostelium.
Methods in enzymology 1994;237():387-408.
1994: Bominaar A A; Van Haastert P J
Phospholipase C activity in Dictyostelium discoideum using endogenous nonradioactive phosphatidylinositol 4,5-bisphosphate as substrate.
Methods in enzymology 1994;238():207-18.
1993: Kuwayama H; Ishida S; Van Haastert P J
Non-chemotactic Dictyostelium discoideum mutants with altered cGMP signal transduction.
The Journal of cell biology 1993;123(6 Pt 1):1453-62.
1993: Bominaar A A; Molijn A C; Pestel M; Veron M; Van Haastert P J
Activation of G-proteins by receptor-stimulated nucleoside diphosphate kinase in Dictyostelium.
The EMBO journal 1993;12(6):2275-9.
1993: Schaap P; van Ments-Cohen M; Soede R D; Brandt R; Firtel R A; Dostmann W; Genieser H G; Jastorff B; van Haastert P J
Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium.
The Journal of biological chemistry 1993;268(9):6323-31.
1993: Bominaar A A; Van Haastert P J
Chemotactic antagonists of cAMP inhibit Dictyostelium phospholipase C.
Journal of cell science 1993;104 ( Pt 1)():181-5.
1992: Peters D J; Snaar-Jagalska B E; Van Haastert P J; Schaap P
Lithium, an inhibitor of cAMP-induced inositol 1,4,5-trisphosphate accumulation in Dictyostelium discoideum, inhibits activation of guanine-nucleotide-binding regulatory proteins, reduces activation of adenylylcyclase, but potentiates activation of guanylyl cyclase by cAMP.
European journal of biochemistry / FEBS 1992;209(1):299-304.
1992: Drayer A L; van Haastert P J
Molecular cloning and expression of a phosphoinositide-specific phospholipase C of Dictyostelium discoideum.
The Journal of biological chemistry 1992;267(26):18387-92.
1992: Van Duijn B; Van Haastert P J
Independent control of locomotion and orientation during Dictyostelium discoideum chemotaxis.
Journal of cell science 1992;102 ( Pt 4)():763-8.
1992: Valkema R; Van Haastert P J
Inhibition of receptor-stimulated guanylyl cyclase by intracellular calcium ions in Dictyostelium cells.
Biochemical and biophysical research communications 1992;186(1):263-8.
1992: Van Haastert P J; Wang M; Bominaar A A; Devreotes P N; Schaap P
cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels.
Molecular biology of the cell 1992;3(6):603-12.
1992: Johnson R L; Van Haastert P J; Kimmel A R; Saxe C L; Jastorff B; Devreotes P N
The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium.
The Journal of biological chemistry 1992;267(7):4600-7.
1991: Bominaar A A; Kesbeke F; Snaar-Jagalska B E; Peters D J; Schaap P; Van Haastert P J
Abberant chemotaxis and differentiation in Dictyostelium mutant fgdC with a defective regulation of receptor-stimulated phosphoinositidase C.
Journal of cell science 1991;100 ( Pt 4)():825-31.
1991: Peters D J; Bominaar A A; Snaar-Jagalska B E; Brandt R; Van Haastert P J; Ceccarelli A; Williams J G; Schaap P
Selective induction of gene expression and second-messenger accumulation in Dictyostelium discoideum by the partial chemotactic antagonist 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9219-23.
1991: van Ments-Cohen M; Genieser H G; Jastorff B; Van Haastert P J; Schaap P
Kinetics and nucleotide specificity of a surface cAMP binding site in Dictyostelium discoideum, which is not down-regulated by cAMP.
FEMS microbiology letters 1991;66(1):9-14.
1991: Johnson R L; Vaughan R A; Caterina M J; Van Haastert P J; Devreotes P N
Overexpression of the cAMP receptor 1 in growing Dictyostelium cells.
Biochemistry 1991;30(28):6982-6.
1991: Snaar-Jagalska B E; Van Es S; Kesbeke F; Van Haastert P J
Activation of a pertussis-toxin-sensitive guanine-nucleotide-binding regulatory protein during desensitization of Dictyostelium discoideum cells to chemotactic signals.
European journal of biochemistry / FEBS 1991;195(3):715-21.
1991: Bominaar A A; Van Dijken P; Draijer R; Van Haastert P J
Developmental regulation of the inositol 1,4,5-trisphosphate phosphatases in Dictyostelium discoideum.
Differentiation; research in biological diversity 1991;46(1):1-5.
1991: Van Haastert P J; Janssens P M; Erneux C
Sensory transduction in eukaryotes. A comparison between Dictyostelium and vertebrate cells.
European journal of biochemistry / FEBS 1991;195(2):289-303.
1991: Van Haastert P J
Transmembrane signal transduction pathways in Dictyostelium.
Advances in second messenger and phosphoprotein research 1991;23():185-226.
1991: Bominaar A A; van der Kaay J; van Haastert P J
Dynamics and function of the inositolcycle in Dictyostelium discoideum.
Developmental genetics 1991;12(1-2):19-24.
1990: Van der Kaay J; Draijer R; Van Haastert P J
Increased conversion of phosphatidylinositol to phosphatidylinositol phosphate in Dictyostelium cells expressing a mutated ras gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9197-201.
1990: Nibbering P H; Zomerdijk T P; van Haastert P J; van Furth R
A competition binding assay for determination of the inositol (1,4,5)-trisphosphate content of human leucocytes.
Biochemical and biophysical research communications 1990;170(2):755-62.
1990: Sun T J; Van Haastert P J; Devreotes P N
Surface cAMP receptors mediate multiple responses during development in Dictyostelium: evidenced by antisense mutagenesis.
The Journal of cell biology 1990;110(5):1549-54.
1990: Snaar-Jagalska B E; Van Haastert P J
Pertussis toxin inhibits cAMP-induced desensitization of adenylate cyclase in Dictyostelium discoideum.
Molecular and cellular biochemistry 1990;92(2):177-89.
1990: Van Duijn B; Vogelzang S A; Ypey D L; Van der Molen L G; Van Haastert P J
Normal chemotaxis in Dictyostelium discoideum cells with a depolarized plasma membrane potential.
Journal of cell science 1990;95 ( Pt 1)():177-83.
1990: Bominaar A A; Van der Kaay J; Kesbeke F; Snaar-Jagalska B E; Van Haastert P J
G-proteins and the inositol cycle in Dictyostelium discoideum.
Biochemical Society symposium 1990;56():71-80.
1989: Firtel R A; van Haastert P J; Kimmel A R; Devreotes P N
G protein linked signal transduction pathways in development: dictyostelium as an experimental system.
Cell 1989;58(2):235-9.
1989: Van Ments-Cohen M; Van Haastert P J
The cyclic nucleotide specificity of eight cAMP-binding proteins in Dictyostelium discoideum is correlated into three groups.
The Journal of biological chemistry 1989;264(15):8717-22.
1989: Peters D J; Van Lookeren Campagne M M; Van Haastert P J; Spek W; Schaap P
Lithium ions induce prestalk-associated gene expression and inhibit prespore gene expression in Dictyostelium discoideum.
Journal of cell science 1989;93 ( Pt 1)():205-10.
1989: Janssens P M; De Jong C C; Vink A A; Van Haastert P J
Regulatory properties of magnesium-dependent guanylate cyclase in Dictyostelium discoideum membranes.
The Journal of biological chemistry 1989;264(8):4329-35.
1989: Van Haastert P J; De Vries M J; Penning L C; Roovers E; Van der Kaay J; Erneux C; Van Lookeren Campagne M M
Chemoattractant and guanosine 5'-[gamma-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in Dictyostelium cells that are labelled with [3H]inositol by electroporation.
The Biochemical journal 1989;258(2):577-86.
1989: Van Haastert P J
Determination of inositol 1,4,5-trisphosphate levels in Dictyostelium by isotope dilution assay.
Analytical biochemistry 1989;177(1):115-9.
1988: Kesbeke F; Van Haastert P J
Reduced cAMP secretion in Dictyostelium discoideum mutant HB3.
Developmental biology 1988;130(2):464-70.
1988: Snaar-Jagalska B E; Van Haastert P J
Dictyostelium discoideum mutant synag 7 with altered G-protein-adenylate cyclase interaction.
Journal of cell science 1988;91 ( Pt 2)():287-94.
1988: Snaar-Jagalska B E; Kesbeke F; Pupillo M; Van Haastert P J
Immunological detection of G-protein alpha-subunits in Dictyostelium discoideum.
Biochemical and biophysical research communications 1988;156(2):757-61.
1988: Van Lookeren Campagne M M; Erneux C; Van Eijk R; Van Haastert P J
Two dephosphorylation pathways of inositol 1,4,5-trisphosphate in homogenates of the cellular slime mould Dictyostelium discoideum.
The Biochemical journal 1988;254(2):343-50.
1988: Ludérus M E; Reymond C D; Van Haastert P J; Van Driel R
Expression of a mutated ras gene in Dictyostelium discoideum alters the binding of cyclic AMP to its chemotactic receptor.
Journal of cell science 1988;90 ( Pt 4)():701-6.
1988: Kesbeke F; Snaar-Jagalska B E; Van Haastert P J
Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein.
The Journal of cell biology 1988;107(2):521-8.
1988: Snaar-Jagalska B E; Jakobs K H; Van Haastert P J
Agonist-stimulated high-affinity GTPase in Dictyostelium membranes.
FEBS letters 1988;236(1):139-44.
1988: Wang M; Van Haastert P J; Devreotes P N; Schaap P
Localization of chemoattractant receptors on Dictyostelium discoideum cells during aggregation and down-regulation.
Developmental biology 1988;128(1):72-7.
1988: Peters D J; Knecht D A; Loomis W F; De Lozanne A; Spudich J; Van Haastert P J
Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain.
Developmental biology 1988;128(1):158-63.
1988: Snaar-Jagalska B E; De Wit R J; Van Haastert P J
Pertussis toxin inhibits cAMP surface receptor-stimulated binding of [35S]GTP gamma S to Dictyostelium discoideum membranes.
FEBS letters 1988;232(1):148-52.
1988: Snaar-Jagalska B E; Devreotes P N; Van Haastert P J
Ligand-induced modification of a surface cAMP receptor of Dictyostelium discoideum does not require its occupancy.
The Journal of biological chemistry 1988;263(2):897-901.
1988: Snaar-Jagalska B E; Kesbeke F; Van Haastert P J
G-proteins in the signal-transduction pathways of Dictyostelium discoideum.
Developmental genetics 1988;9(4-5):215-26.
1987: Janssens P M; Van Haastert P J
Molecular basis of transmembrane signal transduction in Dictyostelium discoideum.
Microbiological reviews 1987;51(4):396-418.
1987: Van Haastert P J
Kinetics and concentration dependency of cAMP-induced desensitization of a subpopulation of surface cAMP receptors in Dictyostelium discoideum.
Biochemistry 1987;26(23):7518-23.
1987: Van Haastert P J
Differential effects of temperature on cAMP-induced excitation, adaptation, and deadaptation of adenylate and guanylate cyclase in Dictyostelium discoideum.
The Journal of cell biology 1987;105(5):2301-6.
1987: Van Haastert P J; Kesbeke F; Reymond C D; Firtel R A; Luderus E; Van Driel R
Aberrant transmembrane signal transduction in Dictyostelium cells expressing a mutated ras gene.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(14):4905-9.
1987: Van Haastert P J
Adenosine 3', 5'-monophosphorothioate (Rp-isomer) induces down-regulation of surface cyclic AMP receptors without receptor activation in Dictyostelium discoideum.
The Journal of biological chemistry 1987;262(16):7705-10.
1987: Van Haastert P J
Down-regulation of cell surface cyclic AMP receptors and desensitization of cyclic AMP-stimulated adenylate cyclase by cyclic AMP in Dictyostelium discoideum. Kinetics and concentration dependence.
The Journal of biological chemistry 1987;262(16):7700-4.
1987: Van Haastert P J
Alteration of receptor/G-protein interaction by putative endogenous protein kinase activity in Dictyostelium discoideum membranes.
The Journal of biological chemistry 1987;262(7):3239-43.
1987: Van Haastert P J; Snaar-Jagalska B E; Janssens P M
The regulation of adenylate cyclase by guanine nucleotides in Dictyostelium discoideum membranes.
European journal of biochemistry / FEBS 1987;162(2):251-8.
1987: Konijn T M; Van Haastert P J
Measurement of chemotaxis in Dictyostelium.
Methods in cell biology 1987;28():283-98.
1986: Schaap P; Van Lookeren Campagne M M; Van Driel R; Spek W; Van Haastert P J; Pinas J
Postaggregative differentiation induction by cyclic AMP in Dictyostelium: intracellular transduction pathway and requirement for additional stimuli.
Developmental biology 1986;118(1):52-63.
1986: van Haastert P J; de Wit R J; Janssens P M; Kesbeke F; DeGoede J
G-protein-mediated interconversions of cell-surface cAMP receptors and their involvement in excitation and desensitization of guanylate cyclase in Dictyostelium discoideum.
The Journal of biological chemistry 1986;261(15):6904-11.
1985: van Haastert P J
cAMP activates adenylate and guanylate cyclase of Dictyostelium discoideum cells by binding to different classes of cell-surface receptors. A study with extracellular Ca2+.
Biochimica et biophysica acta 1985;846(3):324-33.
1985: Kesbeke F; Baraniak J; Bulgakov R; Jastorff B; Morr M; Petridis G; Stec W J; Seela F; Van Haastert P J
Cyclic nucleotide specificity of the activator and catalytic sites of a cGMP-stimulated cGMP phosphodiesterase from Dictyostelium discoideum.
European journal of biochemistry / FEBS 1985;151(1):179-86.
1985: Van Haastert P J
The modulation of cell surface cAMP receptors from Dictyostelium discoideum by ammonium sulfate.
Biochimica et biophysica acta 1985;845(2):254-60.
1985: Miot F; Van Haastert P J; Erneux C
Specificity of cGMP binding to a purified cGMP-stimulated phosphodiesterase from bovine adrenal tissue.
European journal of biochemistry / FEBS 1985;149(1):59-65.
1985: Van Haastert P J; De Wit R J; Van Lookeren Campagne M M
Ca2+- or phorbol ester- dependent effect of ATP on a subpopulation of cAMP cell-surface receptors in membranes from D. discoideum. A role for protein kinase C.
Biochemical and biophysical research communications 1985;128(1):185-92.
1985: Erneux C; Miot F; Van Haastert P J; Jastorff B
The binding of cyclic nucleotide analogs to a purified cyclic GMP-stimulated phosphodiesterase from bovine adrenal tissue.
Journal of cyclic nucleotide and protein phosphorylation research 1985;10(5):463-72.
1984: Van Haastert P J; De Wit R J
Demonstration of receptor heterogeneity and affinity modulation by nonequilibrium binding experiments. The cell surface cAMP receptor of Dictyostelium discoideum.
The Journal of biological chemistry 1984;259(21):13321-8.
1984: Van Haastert P J
Guanine nucleotides modulate cell surface cAMP-binding sites in membranes from Dictyostelium discoideum.
Biochemical and biophysical research communications 1984;124(2):597-604.
1984: Van Haastert P J; Van Driel R; Jastorff B; Baraniak J; Stec W J; De Wit R J
Competitive cAMP antagonists for cAMP-receptor proteins.
The Journal of biological chemistry 1984;259(16):10020-4.
1984: de Wit R J; Hekstra D; Jastorff B; Stec W J; Baraniak J; Van Driel R; Van Haastert P J
Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases.
European journal of biochemistry / FEBS 1984;142(2):255-60.
1984: Van Haastert P J; Van Lookeren Campagne M M
Transient kinetics of a cGMP-dependent cGMP-specific phosphodiesterase from Dictyostelium discoideum.
The Journal of cell biology 1984;98(2):709-16.
1984: van Waarde A; van Haastert P J
Transmethylation inhibitors decrease chemotactic sensitivity and delay cell aggregation in Dictyostelium discoideum.
Journal of bacteriology 1984;157(2):368-74.
1983: Van Lookeren Campagne M M; Van Haastert P J
A sensitive cyclic nucleotide phosphodiesterase assay for transient enzyme kinetics.
Analytical biochemistry 1983;135(1):146-50.
1983: Van Haastert P J
Relationship between adaptation of the folic acid and the cAMP mediated cGMP response in Dictyostelium.
Biochemical and biophysical research communications 1983;115(1):130-6.
1983: Van Haastert P J
Binding of cAMP and adenosine derivatives to Dictyostelium discoideum cells. Relationships of binding, chemotactic, and antagonistic activities.
The Journal of biological chemistry 1983;258(16):9643-8.
1983: Van Haastert P J; Kien E
Binding of cAMP derivatives to Dictyostelium discoideum cells. Activation mechanism of the cell surface cAMP receptor.
The Journal of biological chemistry 1983;258(16):9636-42.
1983: Van Haastert P J
Sensory adaptation of Dictyostelium discoideum cells to chemotactic signals.
The Journal of cell biology 1983;96(6):1559-65.
1983: Van Haastert P J; Dijkgraaf P A; Konijn T M; Abbad E G; Petridis G; Jastorff B
Substrate specificity of cyclic nucleotide phosphodiesterase from beef heart and from Dictyostelium discoideum.
European journal of biochemistry / FEBS 1983;131(3):659-66.
1983: Van Haastert P J; Van der Heijden P R
Excitation, adaptation, and deadaptation of the cAMP-mediated cGMP response in Dictyostelium discoideum.
The Journal of cell biology 1983;96(2):347-53.
1982: Van Haastert P J; Bijleveld W; Konijn T M
Phosphodiesterase induction in Dictyostelium discoideum by inhibition of extracellular phosphodiesterase activity.
Developmental biology 1982;94(1):240-5.
1982: Van Haastert P J; De Wit R J; Grijpma Y; Konijn T M
Identification of a pterin as the acrasin of the cellular slime mold Dictyostelium lacteum.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(20):6270-4.
1982: van Haastert P J; van Lookeren Campagne M M; Ross F M
Altered cGMP-phosphodiesterase activity in chemotactic mutants of Dictyostelium discoideum.
FEBS letters 1982;147(2):149-52.
1982: van Haastert P J; Pasveer F J; van der Meer R C; van der Heijden P R; van Walsum H; Konijn T M
Evidence for a messenger function of cyclic GMP during phosphodiesterase induction in Dictyostelium discoideum.
Journal of bacteriology 1982;152(1):232-8.
1982: van Haastert P J; De Wit R J; Konijn T M
Antagonists of chemoattractants reveal separate receptors for cAMP, folic acid and pterin in Dictyostelium.
Experimental cell research 1982;140(2):453-6.
1982: Van Haastert P J; Van Walsum H; Pasveer F J
Nonequilibrium kinetics of a cyclic GMP-binding protein in Dictyostelium discoideum.
The Journal of cell biology 1982;94(2):271-8.
1982: van Haastert P J; Konijn T M
Signal transduction in the cellular slime molds.
Molecular and cellular endocrinology 1982;26(1-2):1-17.
1982: van Haastert P J; van Walsum H; van der Meer R C; Bulgakov R; Konijn T M
Specificity of the cyclic GMP-binding activity and of a cyclic GMP-dependent cyclic GMP phosphodiesterase in Dictyostelium discoideum.
Molecular and cellular endocrinology 1982;25(2):171-82.
1982: Van Haastert P J; Jastorff B; Pinas J E; Konijn T M
Analogs of cyclic AMP as chemoattractants and inhibitors of Dictyostelium chemotaxis.
Journal of bacteriology 1982;149(1):99-105.
1981: Van Haastert P J; Van Der Meer R C; Konijn T M
Evidence that the rate of association of adenosine 3',5'-monophosphate to its chemotactic receptor induces phosphodiesterase activity in Dictyostelium discoideum.
Journal of bacteriology 1981;147(1):170-5.
1978: Mato J M; Woelders H; van Haastert P J; Konijn T M
Cyclic GMP binding activity in Dictyostelium discoideum.
FEBS letters 1978;90(2):261-4.
1978: Mato J M; van Haastert P J; Krens F A; Konijn T M
Chemotaxis in Dictyostelium discoideum: effect of concanavalin A on chemoattractant mediated cyclic gmp accumulation anlight scattering decrease.
Cell biology international reports 1978;2(2):163-70.
1977: Mato J M; Van Haastert P J; Krens F A; Rhijnsburger E H; Dobbe F C; Konijn T M
Cyclic AMP and folic acid mediated cyclic GMP accumulation in Dictyostelium discoideum.
FEBS letters 1977;79(2):331-6.
1977: Mato J M; Krens F A; van Haastert P J; Konijn T M
Unified control of chemotaxis and cAMP mediated cGMP accumulation by cAMP in Dictyostelium discoideum.
Biochemical and biophysical research communications 1977;77(1):399-402.
1977: Mato J M; van Haastert P J; Krens F A; Konijn T M
An acrasin-like attractant from yeast extract specific for Dictyostelium lacteum.
Developmental biology 1977;57(2):450-3.
1977: Mato J M; Krens F A; van Haastert P J; Konijn T M
3':5'-cyclic AMP-dependent 3':5'-cyclic GMP accumulation in Dictyostelium discoideum.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(6):2348-51.

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