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Wei-Shuo FANG

Research Profile

Genes & Molecular Sequences

Molecular Structure

Chemicals & Drugs

Concepts & Ideas

Living Beings

Procedures

Anatomy

Phenomena

Magnetic Resonance Spectroscopy

Physiology

Drug Resistance, Neoplasm

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Publications

TOP 3
Claire Coderch; J Fernando Díaz; Wei-Shuo FANG; Angeles Canales; Jesús Jiménez-Barbero; Javier Klett; Yun-Tao Ma; Ruth Matesanz; Antonio Morreale; Benet Pera; Wang Shaorong; Yong Tang; Shu-En Zhang; Federico Gago
A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.
Laura Cosentino; J Fernando Díaz; Wei-Shuo FANG; Jérémie Fournier dit Chabert; Paul M Loadman; Qasem M A Abdallah; Hamdy Abdel-Rahman; Isabel Barasoain; Philip A Burns; Kaniz F Chowdury; Mariano Redondo-Horcajo; Ana Rita Santos; Steven D Shnyder; Victoria Vinader; Ying Zhao; Klaus Pors
Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.
Shu-En Zhang; Ying Zhao; Di Zhou; Jia-Yi Tao; Shao-Rong Wang; Wei-Shuo FANG
Isolation, identification, semi-synthesis of aziditaxel derivatives and their biological evaluation.

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All Publications

2013: Claire Coderch; J Fernando Díaz; Wei-Shuo FANG; Angeles Canales; Jesús Jiménez-Barbero; Javier Klett; Yun-Tao Ma; Ruth Matesanz; Antonio Morreale; Benet Pera; Wang Shaorong; Yong Tang; Shu-En Zhang; Federico Gago
A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.
Organic & biomolecular chemistry 2013;11(18):3046-56.
2012: Laura Cosentino; J Fernando Díaz; Wei-Shuo FANG; Jérémie Fournier dit Chabert; Paul M Loadman; Qasem M A Abdallah; Hamdy Abdel-Rahman; Isabel Barasoain; Philip A Burns; Kaniz F Chowdury; Mariano Redondo-Horcajo; Ana Rita Santos; Steven D Shnyder; Victoria Vinader; Ying Zhao; Klaus Pors
Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.
Journal of medicinal chemistry 2012;55(24):11062-6.
2012: Shu-En Zhang; Ying Zhao; Di Zhou; Jia-Yi Tao; Shao-Rong Wang; Wei-Shuo FANG
Isolation, identification, semi-synthesis of aziditaxel derivatives and their biological evaluation.
Journal of Asian natural products research 2012;14(5):463-75.
2012: Jia-Yi Tao; Feng Zhao; Sheng-Jun Dai; Wei-Shuo FANG; Jun-Feng Liu; Ke Liu
New ursane-type triterpene with NO production suppressing activity from Nauclea officinalis.
Journal of Asian natural products research 2012;14(2):97-104.
2011: Xi Xiao; Ying Zhao; Isabel Barasoain; Hui Chen; Joseph W K Chu; J Fernando Diaz; Yan Li; Peihua Lu; Frances J Sharom; Li Sheng; Chiara Trigili; Ju Wu; Wei-Shuo FANG
Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.
Bioorganic & medicinal chemistry letters 2011;21(16):4852-6.
2010: Na Guo; Ying Zhao; Wei-Shuo FANG
Biotransformation of 3-oxo-oleanolic acid by Absidia glauca.
Planta medica 2010;76(16):1904-7.
2010: Liang Lv; Xiao-Yan Tian; Wei-Shuo FANG
Three new antioxidant C-glucosylanthrones from Aloe nobilis.
Journal of Asian natural products research 2010;12(6):443-7.
2010: Xiao-Yan Tian; Ying Zhao; Shi-Shan Yu; Wei-Shuo FANG
BACE1 (beta-secretase) inhibitory phenolic acids and a novel sesquiterpenoid from Homalomena occulta.
Chemistry & biodiversity 2010;7(4):984-92.
2010: Isabel Barasoain; Ana M García-Carril; Ruth Matesanz; Giorgio Maccari; Chiara Trigili; Mattia Mori; Jing-Zhe Shi; Wei-Shuo FANG; José M Andreu; Maurizio Botta; J Fernando Díaz
Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.
Chemistry & biology 2010;17(3):243-53.
2010: Qing-Yun Yang; Chun-Suo Yao; Wei-Shuo FANG
A new triglucosylated naphthalene glycoside from Aloe vera L.
Fitoterapia 2010;81(1):59-62.
2009: Li Zhang; Juan-Juan Hu; Jian-Wei Lin; Wei-Shuo FANG; Guan-Hua Du
Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (C.B. Clarke) Höeck.
Journal of ethnopharmacology 2009;123(3):510-4.
2009: Ying Zhao; Wei-Shuo FANG; Klaus Pors
Microtubule stabilising agents for cancer chemotherapy.
Expert opinion on therapeutic patents 2009;19(5):607-22.
2009: Xuan Li; Isabel Barasoain; Ruth Matesanz; J Fernando Díaz; Wei-Shuo FANG
Synthesis and biological activities of high affinity taxane-based fluorescent probes.
Bioorganic & medicinal chemistry letters 2009;19(3):751-4.
2009: Shao-Rong Wang; Wei-Shuo FANG
Pentacyclic triterpenoids and their saponins with apoptosis-inducing activity.
Current topics in medicinal chemistry 2009;9(16):1581-96.
2009: Xiao-Yan Tian; Ying-Hong Wang; Qing-Yun Yang; Shi-Shan Yu; Wei-Shuo FANG
Jacaranone analogs from Senecio scandens.
Journal of Asian natural products research 2009;11(1):63-8.
2008: Dong Wang; Xiao-qiu Liu; Chun-Suo Yao; Wei-Shuo FANG
[Studies on chemical constituents from herbs of Botrychium lanuginosum].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2008;33(22):2627-9.
2008: Wei-Shuo FANG; Shao-Rong Wang
Structural studies of taxol analogues for drug discovery.
Expert opinion on drug discovery 2008;3(9):1109-22.
2008: Ruth Matesanz; Isabel Barasoain; Chun-Gang Yang; Lei Wang; Xuan Li; Concepción de Inés; Claire Coderch; Federico Gago; Jesús Jiménez Barbero; José Manuel Andreu; Wei-Shuo FANG; J Fernando Díaz
Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.
Chemistry & biology 2008;15(6):573-85.
2008: Liang Lv; Qing-Yun Yang; Ying Zhao; Chun-Suo Yao; Yang Sun; Eun-Ju Yang; Kyung-Sik Song; Inhee Mook-Jung; Wei-Shuo FANG
BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.
Planta medica 2008;74(5):540-5.
2008: Hua Sun; Wei-Shuo FANG; Chun Hu
An efficient semi-synthesis and structure revision of a cytotoxic triterpenoid 25-acetoxy-3alpha-hydroxyolean-12-en-28-oic acid from Liquidamber styraciflua.
Journal of Asian natural products research 2008;10(3-4):297-305.
2007: Xiao-Yan Tian; Ying-Hong Wang; Hong-Yue Liu; Shi-Shan Yu; Wei-Shuo FANG
On the chemical constituents of Dipsacus asper.
Chemical & pharmaceutical bulletin 2007;55(12):1677-81.
2007: Lei Wang; Ana A Alcaraz; Ruth Matesanz; Chun-Gang Yang; Isabel Barasoain; J Fernando Díaz; Ye-Zhi Li; James P Snyder; Wei-Shuo FANG
Synthesis, biological evaluations, and tubulin binding poses of C-2alpha sulfur linked taxol analogues.
Bioorganic & medicinal chemistry letters 2007;17(11):3191-4.
2007: Chun-Gang Yang; Isabel Barasoain; Xuan Li; Ruth Matesanz; Ronghua Liu; Frances Sharom; Da-Li Yin; J Fernando Díaz; Wei-Shuo FANG
Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines.
ChemMedChem 2007;2(5):691-701.
2007: Q-Y Yang; Xiao-Yan Tian; Wei-Shuo FANG
Bioactive coumarins from Boenninghausenia sessilicarpa.
Journal of Asian natural products research 2007;9(1):59-65.
2006: Bo Gao; Chun-Suo Yao; Jin-Yun Zhou; Ruo-yun Chen; Wei-Shuo FANG
[Active constituents from Aloe arborescens as BACE inhibitors].
Yao xue xue bao = Acta pharmaceutica Sinica 2006;41(10):1000-3.
2006: Xiao-Yan Tian; Ying-Hong Wang; Shi-Shan Yu; Wei-Shuo FANG
Two novel tetrairidoid glucosides from Dipsacus asper.
Organic letters 2006;8(10):2179-82.
2006: Xiao-Yan Tian; Ying-Hong Wang; Qing-Yun Yang; Xin Liu; Wei-Shuo FANG; Shi-Shan Yu
Jacaranone glycosides from Senecio scandens.
Journal of Asian natural products research 2006;8(1-2):125-32.
2005: Wei-Shuo FANG; Xiao-Tian Liang
Recent progress in structure activity relationship and mechanistic studies of taxol analogues.
Mini reviews in medicinal chemistry 2005;5(1):1-12.
2002: Xian-dao Pan; Wei-Shuo FANG
Recent progress in structure-activity relationship studies on the anticancer drug colchicine and its analogues.
Yao xue xue bao = Acta pharmaceutica Sinica 2002;37(10):821-7.
2002: Wei-Shuo FANG; Ying Liu; Hong-Yan Liu; Shao-Feng Xu; Liang Wang; Qi-Cheng Fang
Synthesis and cytotoxicity of 2alpha-amido docetaxel analogues.
Bioorganic & medicinal chemistry letters 2002;12(11):1543-6.
2001: G M Liu; Wei-Shuo FANG; J F Qian; H Lan
Distribution of paclitaxel and its congeners in Taxus mairei.
Fitoterapia 2001;72(7):743-6.
2001: H Xu; Wei-Shuo FANG; Xiao-Guang Chen; Wen-Yi He; Ke-di Cheng
Cytochalasin D from Hypocrella bambusae.
Journal of Asian natural products research 2001;3(2):151-5.
1998: Wei-Shuo FANG; Q C Fang; L S Xu; Xiao-Tian Liang
[Chemical reactivities and the core modifications of paclitaxel and its analogs].
Yao xue xue bao = Acta pharmaceutica Sinica 1998;33(4):310-20.
1996: Wei-Shuo FANG; Q C Fang; Xiao-Tian Liang
Bicyclic taxoids from needles of Taxus chinensis.
Planta medica 1996;62(6):567-9.