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Michael Müller

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TOP 3
Michael Müller; Georg A Sprenger; Martina Pohl
CC bond formation using ThDP-dependent lyases.
Sheril Alex; Sa'ad Al-Lahham; Tom Amolo; Alexandre M J J Bonvin; Jeffrey S Grinstead; Anders K Haakonsson; Daniëlle Haenen; Guido J E J Hooiveld; René Houtman; Eric Kalkhoven; Arjen Koppen; Katja Lange; Susanne Mandrup; Karin Mudde; Michael Müller; Han Roelofsen; Ewa Szalowska; Bart van der Burg; Sander Kersten
Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.
Daniëlle Haenen; Guido Bosch; Bas Kemp; Michael Müller; Odette Pérez Gutiérrez; Hauke Smidt; Carol Souza da Silva; Jeroen van Arkel; Joost J G C van den Borne; Ingrid M van der Meer; Jing Zhang; Guido J E J Hooiveld
A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine.

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All Publications

2013: Michael Müller; Georg A Sprenger; Martina Pohl
CC bond formation using ThDP-dependent lyases.
Current opinion in chemical biology 2013;17(2):261-70.
2013: Sheril Alex; Sa'ad Al-Lahham; Tom Amolo; Alexandre M J J Bonvin; Jeffrey S Grinstead; Anders K Haakonsson; Daniëlle Haenen; Guido J E J Hooiveld; René Houtman; Eric Kalkhoven; Arjen Koppen; Katja Lange; Susanne Mandrup; Karin Mudde; Michael Müller; Han Roelofsen; Ewa Szalowska; Bart van der Burg; Sander Kersten
Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.
Molecular and cellular biology 2013;33(7):1303-16.
2013: Daniëlle Haenen; Guido Bosch; Bas Kemp; Michael Müller; Odette Pérez Gutiérrez; Hauke Smidt; Carol Souza da Silva; Jeroen van Arkel; Joost J G C van den Borne; Ingrid M van der Meer; Jing Zhang; Guido J E J Hooiveld
A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine.
The Journal of nutrition 2013;143(3):274-83.
2013: Maryam Beigi; Volker Brecht; Werner Hummel; Finian J Leeper; Patrizia Lehwald; Sabrina Loschonsky; Susana L A Andrade; Michael Müller
α-Hydroxy-β-keto acid rearrangement-decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations.
Organic & biomolecular chemistry 2013;11(2):252-6.
2013: Diederik Esser; Ronald M A Henry; Michael Müller; Els Oosterink; Jos op 't Roodt; Coen D A Stehouwer; Lydia A Afman
Vascular and inflammatory high fat meal responses in young healthy men; a discriminative role of IL-8 observed in a randomized trial.
PloS one 2013;8(2):e53474.
2012: Nicole J W de Wit; Marco Mensink; Lydia A Afman; Michael Müller
Phenotyping the effect of diet on non-alcoholic fatty liver disease.
Journal of hepatology 2012;57(6):1370-3.
2012: Christian Gil Girol; Stefan Günther; Thorsten Heinekamp; Wolfgang Hüttel; Axel A Brakhage; Katja Maria Fisch; Jörn Piel; Michael Müller
Regio- and stereoselective oxidative phenol coupling in Aspergillus niger.
Angewandte Chemie (International ed. in English) 2012;51(39):9788-91.
2012: Michael A Schätzle; Sascha Ferlaino; Syed Masood Husain; Michael Müller
Tautomers of anthrahydroquinones: enzymatic reduction and implications for chrysophanol, monodictyphenone, and related xanthone biosyntheses.
Journal of the American Chemical Society 2012;134(36):14742-5.
2012: Nicole de Wit; Muriel Derrien; Caroline Duval; Shohreh Keshtkar; Michiel Kleerebezem; Michael Müller; Els Oosterink; Hanneke Bosch-Vermeulen; Johan de Vogel-van den Bosch; Roelof Van Der Meer
Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine.
American journal of physiology. Gastrointestinal and liver physiology 2012;303(5):G589-99.
2012: Susan J van Dijk; Marieke B Bos; Lisette C P G M de Groot; Jeanne H M de Vries; Edith J M Feskens; Michael Müller; Lydia A Afman
Consumption of a high monounsaturated fat diet reduces oxidative phosphorylation gene expression in peripheral blood mononuclear cells of abdominally overweight men and women.
The Journal of nutrition 2012;142(7):1219-25.
2012: Noortje IJssennagger; Denise Jonker-Termont; Michael Müller; Anneke Rijnierse; Nicole de Wit; Jan Dekker; Roelof Van Der Meer
Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon.
Gut 2012;61(7):1041-9.
2012: Anastasia Georgiadi; Mark V Boekschoten; Michael Müller; Sander Kersten
Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.
Physiological genomics 2012;44(6):352-61.
2012: Michael A Schätzle; Michael Richter; Stephan Flemming; Stefan Günther; Syed Masood Husain; Michael Müller
Tetrahydroxynaphthalene reductase: catalytic properties of an enzyme involved in reductive asymmetric naphthol dearomatization.
Angewandte Chemie (International ed. in English) 2012;51(11):2643-6.
2012: Maryam Rakhshandehroo; Rinke Stienstra; Ronald P Mensink; Michael Müller; Marjolijn C E Bragt; Nicole J de Wit; Martin Haluzik; Sander Kersten
Plasma mannose-binding lectin is stimulated by PPARα in humans.
American journal of physiology. Endocrinology and metabolism 2012;302(5):E595-602.
2012: Noortje Ĳssennagger; Michiel Kleerebezem; Michael Müller; Anneke Rijnierse; Bartholomeus van den Bogert; Jan Dekker; Muriel Derrien; Gerdien M van Doorn; Roelof Van Der Meer
Dietary heme alters microbiota and mucosa of mouse colon without functional changes in host-microbe cross-talk.
PloS one 2012;7(12):e49868.
2012: Milène Catoire; Roland Hangelbroek; Marco Mensink; Michael Müller; Patrick Schrauwen; Mark V Boekschoten; Sander Kersten
Pronounced effects of acute endurance exercise on gene expression in resting and exercising human skeletal muscle.
PloS one 2012;7(11):e51066.
2012: Jessica Schwarz; Daniel Tomé; Annemarie Baars; Guido J E J Hooiveld; Michael Müller
Dietary protein affects gene expression and prevents lipid accumulation in the liver in mice.
PloS one 2012;7(10):e47303.
2012: Yingchang Lu; Audrey H H Merry; Michael Müller; Leo J Schouten; P Eline Slagboom; Anika Vaarhorst; Piet A van den Brandt; Anton P M Gorgels; Bas Heijmans; Robert Hovenier; Sandra Imholz; Jolanda M A Boer; Martijn E T Dollé; Edith J M Feskens
Markers of endogenous desaturase activity and risk of coronary heart disease in the CAREMA cohort study.
PloS one 2012;7(7):e41681.
2012: Noortje Ijssennagger; Michael Müller; Nicole de Wit; Roelof Van Der Meer
Dietary heme-mediated PPARα activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon.
PloS one 2012;7(8):e43260.
2012: Susan J van Dijk; Diederik Esser; Edith J M Feskens; Marco Mensink; Michael Müller; Lydia A Afman
Responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes: a randomized trial.
PloS one 2012;7(7):e41388.
2012: Mohammad Ohid Ullah; Michael Müller; Guido J E J Hooiveld
An Integrated Statistical Approach to Compare Transcriptomics Data Across Experiments: A Case Study on the Identification of Candidate Target Genes of the Transcription Factor PPARα.
Bioinformatics and biology insights 2012;6():145-54.
2012: Yingchang Lu; Michael Müller; Roza M Barsova; Jolanda M A Boer; Olga Favorova; Edith J M Feskens; Anuj Goel
TGFB1 genetic polymorphisms and coronary heart disease risk: a meta-analysis.
BMC medical genetics 2012;13():39.
2011: Yingchang Lu; Michael Müller; Suzan Wopereis; Mark V Boekschoten; Sander Kersten
Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice.
Physiological genomics 2011;43(23):1307-18.
2011: Leif E Sander; Joel A Swanson; Derk Amsen; Mark V Boekschoten; Christopher Dascher; Michael J Davis; Michael Müller; Bernard Ryffel; Julie M. Blander
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity.
Nature 2011;474(7351):385-9.
2011: Isabel Rubio-Aliaga; Manuela Sailer; Gerard A McLoughlin; Mark V Boekschoten; Marjan van Erk; Eva-Maria Bachmair; Evert M van Schothorst; Jaap Keijer; Susan L Coort; Chris Evelo; Mike joseph Gibney; Hannelore Daniel; Michael Müller; Robert Kleemann; Baukje de Roos; Lorraine Brennan
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention.
Physiological genomics 2011;43(8):408-16.
2011: Nicole J W de Wit; Hanneke Bosch-Vermeulen; Els Oosterink; Michael Müller; Roelof Van Der Meer
Supplementary dietary calcium stimulates faecal fat and bile acid excretion, but does not protect against obesity and insulin resistance in C57BL/6J mice.
The British journal of nutrition 2011;105(7):1005-11.
2011: Maxi Meissner; Michael Müller; Dirk-Jan Reijngoud; Theo H Van Dijk; Theo Boer; Albert Gerding; Albert K Groen; Rick Havinga; Hilde Herrema; Folkert Kuipers
Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.
PloS one 2011;6(11):e24564.
2011: Muriel Derrien; Guido Hooiveld; Michael Müller; Elisabeth Norin; Peter van Baarlen; Willem M de Vos
Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila.
Frontiers in microbiology 2011;2():166.
2011: Nicole J W de Wit; Mark V Boekschoten; Eva-Maria Bachmair; Guido J E J Hooiveld; Philip J de Groot; Isabel Rubio-Aliaga; Hannelore Daniel; Michael Müller
Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice.
PloS one 2011;6(4):e19145.
2010: Rinke Stienstra; Leo A B Joosten; Tim Koenen; Berry van Tits; Janna A van Diepen; Sjoerd van den Berg; Patrick C N Rensen; Peter J Voshol; Giamila Fantuzzi; Anneke Hijmans; Sander Kersten; Michael Müller; Wim B van den Berg; Nico van Rooijen; Martin Wabitsch; Bart Jan Kullberg; Jos W M van der Meer; Thirumala Kanneganti; Cees J Tack; Mihai G Netea
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
Cell metabolism 2010;12(6):593-605.
2010: Laeticia Lichtenstein; Frits Mattijssen; Nicole J de Wit; Anastasia Georgiadi; Guido J Hooiveld; Roelof Van Der Meer; Yin He; Ling Qi; Anja Köster; Jouke T Tamsma; Nguan Soon Tan; Michael Müller; Sander Kersten
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages.
Cell metabolism 2010;12(6):580-92.
2010: Caroline Duval; Uwe Thissen; Shohreh Keshtkar; Bertrand Accart; Rinke Stienstra; Mark V Boekschoten; Tania Roskams; Sander Kersten; Michael Müller
Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice.
Diabetes 2010;59(12):3181-91.
2010: Yingchang Lu; Edith J M Feskens; Jolanda M A Boer; Sandra Imholz; W M Monique Verschuren; Cisca Wijmenga; Anika Vaarhorst; Eline Slagboom; Michael Müller; Martijn E T Dollé
Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study.
Atherosclerosis 2010;213(1):200-5.
2010: Carola Dresen; Michael Richter; Martina Pohl; Steffen Lüdeke; Michael Müller
The enzymatic asymmetric conjugate umpolung reaction.
Angewandte Chemie (International ed. in English) 2010;49(37):6600-3.
2010: Vítor Martins dos Santos; Michael Müller; Willem M de Vos
Systems biology of the gut: the interplay of food, microbiota and host at the mucosal interface.
Current opinion in biotechnology 2010;21(4):539-50.
2010: Martina Daum; Hans-Jörg Schnell; Simone Herrmann; Andreas Günther; Renato Murillo; Rolf Müller; Philippe Bisel; Michael Müller; Andreas Bechthold
Functions of genes and enzymes involved in phenalinolactone biosynthesis.
Chembiochem : a European journal of chemical biology 2010;11(10):1383-91.
2010: Yingchang Lu; Edith Jm Feskens; Martijn E T Dollé; Sandra Imholz; W M Monique Verschuren; Michael Müller; Jolanda Ma Boer
Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study.
The American journal of clinical nutrition 2010;92(1):258-65.
2010: Anastasia Georgiadi; Laeticia Lichtenstein; Tatjana Degenhardt; Mark V Boekschoten; Marc van Bilsen; Beatrice Desvergne; Michael Müller; Sander Kersten
Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.
Circulation research 2010;106(11):1712-21.
2010: David L M van der Meer; Tatjana Degenhardt; Sami Väisänen; Philip J de Groot; Merja Heinäniemi; Sacco C de Vries; Michael Müller; Carsten Carlberg; Sander Kersten
Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis.
Nucleic acids research 2010;38(9):2839-50.
2010: Yingchang Lu; Edith J M Feskens; Jolanda M A Boer; Michael Müller
The potential influence of genetic variants in genes along bile acid and bile metabolic pathway on blood cholesterol levels in the population.
Atherosclerosis 2010;210(1):14-27.
2010: Patrizia Lehwald; Michael Richter; Caroline Röhr; Hung-wen Liu; Michael Müller
Enantioselective intermolecular aldehyde-ketone cross-coupling through an enzymatic carboligation reaction.
Angewandte Chemie (International ed. in English) 2010;49(13):2389-92.
2010: Linda M Sanderson; Mark V Boekschoten; Beatrice Desvergne; Michael Müller; Sander Kersten
Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.
Physiological genomics 2010;41(1):42-52.
2010: Hilde Herrema; Maxi Meissner; Theo H Van Dijk; Gemma Brufau; Renze Boverhof; Maaike H Oosterveer; Dirk-Jan Reijngoud; Michael Müller; Frans Stellaard; Albert K Groen; Folkert Kuipers
Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptor alpha-controlled metabolic pathways in mice.
Hepatology (Baltimore, Md.) 2010;51(3):806-16.
2010: Rinke Stienstra; Fredy Saudale; Caroline Duval; Shohreh Keshtkar; Johanna E M Groener; Nico van Rooijen; Bart Staels; Sander Kersten; Michael Müller
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity.
Hepatology (Baltimore, Md.) 2010;51(2):511-22.
2010: Bart L T Vaes; Carolien Lute; Sebastian P van der Woning; Ester Piek; Jenny Vermeer; Henk J Blom; John C Mathers; Michael Müller; Lisette C P G M de Groot; Wilma T Steegenga
Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism.
Bone 2010;46(2):514-23.
2010: Susan J van Dijk; Edith J M Feskens; A Geert Heidema; Marieke B Bos; Ondine van de Rest; Johanna M Geleijnse; Lisette C P G M de Groot; Michael Müller; Lydia A Afman
Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects.
PloS one 2010;5(12):e14422.
2010: Maryam Rakhshandehroo; Bianca Knoch; Michael Müller; Sander Kersten
Peroxisome proliferator-activated receptor alpha target genes.
PPAR research 2010;2010():.
2010: Mark Bouwens; Mechteld Grootte Bromhaar; Jenny Jansen; Michael Müller; Lydia A Afman
Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles.
The American journal of clinical nutrition 2010;91(1):208-17.
2009: Jan Zarzycki; Volker Brecht; Michael Müller; Georg Fuchs
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(50):21317-22.
2009: Susan J van Dijk; Edith J M Feskens; Marieke B Bos; Dianne W M Hoelen; Rik Heijligenberg; Mechteld Grootte Bromhaar; Lisette C P G M de Groot; Jeanne H M de Vries; Michael Müller; Lydia A Afman
A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome.
The American journal of clinical nutrition 2009;90(6):1656-64.
2009: Linda M Sanderson; Tatjana Degenhardt; Arjen Koppen; Eric Kalkhoven; Beatrice Desvergne; Michael Müller; Sander Kersten
Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.
Molecular and cellular biology 2009;29(23):6257-67.
2009: Sander Kersten; Michael Müller
Dropping liver fat droplets.
Hepatology (Baltimore, Md.) 2009;50(2):645-7.
2009: Mark Bouwens; Ondine van de Rest; Neele Dellschaft; Mechteld Grootte Bromhaar; Lisette C P G M de Groot; Johanna M Geleijnse; Michael Müller; Lydia A Afman
Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.
The American journal of clinical nutrition 2009;90(2):415-24.
2009: Arne Giebeler; Mark V Boekschoten; Christian Klein; Malgorzata Borowiak; Carmen Birchmeier; Nikolaus Gassler; Hermann E Wasmuth; Michael Müller; Christian Trautwein; Konrad L Streetz
c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice.
Gastroenterology 2009;137(1):297-308, 308.e1-4.
2009: Tobias J Erb; Volker Brecht; Georg Fuchs; Michael Müller; Birgit E Alber
Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8871-6.
2009: Michael Müller; Dörte Gocke; Martina Pohl
Thiamin diphosphate in biological chemistry: exploitation of diverse thiamin diphosphate-dependent enzymes for asymmetric chemoenzymatic synthesis.
The FEBS journal 2009;276(11):2894-904.
2009: Sander Kersten; Laeticia Lichtenstein; Emma Steenbergen; Karin Mudde; Henk F.J. Hendriks; Matthijs K Hesselink; Patrick Schrauwen; Michael Müller
Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):969-74.
2009: Eileen F Murphy; Guido J Hooiveld; Michael Müller; Raffaele A Calogero; Kevin D Cashman
The effect of trans-10, cis-12 conjugated linoleic acid on gene expression profiles related to lipid metabolism in human intestinal-like Caco-2 cells.
Genes & nutrition 2009;4(2):103-12.
2009: Bart L T Vaes; Carolien Lute; Henk J Blom; Nathalie Bravenboer; Teun J de Vries; Vincent Everts; Rosalie A M Dhonukshe-Rutten; Michael Müller; Lisette C P G M de Groot; Wilma T Steegenga
Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid.
Calcified tissue international 2009;84(5):413-22.
2009: Maryam Rakhshandehroo; Guido Hooiveld; Michael Müller; Sander Kersten
Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human.
PloS one 2009;4(8):e6796.
2009: Marijana Radonjic; Jorn R de Haan; Marjan J van Erk; Ko Willems van Dijk; Sjoerd van den Berg; Philip J de Groot; Michael Müller; Ben van Ommen
Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program.
PloS one 2009;4(8):e6646.
2008: P J De Groot; C Reiff; C Mayer; Michael Müller
NuGO contributions to GenePattern.
Genes & nutrition 2008;3(3-4):143-6.
2008: Rinke Stienstra; Caroline Duval; Shohreh Keshtkar; Jeroen van der Laak; Sander Kersten; Michael Müller
Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.
The Journal of biological chemistry 2008;283(33):22620-7.
2008: Ben van Ommen; Jaap Keijer; Robert Kleemann; Ruan Elliott; Christian Andre Drevon; Harry McArdle; Mike Gibney; Michael Müller
The challenges for molecular nutrition research 2: quantification of the nutritional phenotype.
Genes & nutrition 2008;3(2):51-9.
2008: Hilde Herrema; Terry G J Derks; Theo H Van Dijk; Vincent Bloks; Albert Gerding; Rick Havinga; Uwe J F Tietge; Michael Müller; G Peter A Smit; Folkert Kuipers; Dirk-Jan Reijngoud
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.
Hepatology (Baltimore, Md.) 2008;47(6):1894-904.
2008: Heleen M de Vogel-van den Bosch; Nicole J W de Wit; Guido J E J Hooiveld; Hanneke Vermeulen; Jelske N van der Veen; Sander M Houten; Folkert Kuipers; Michael Müller; Roelof van der Meer
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(5):G1171-80.
2008: Janneke de Wilde; Ronny Mohren; Sjoerd van den Berg; Mark Boekschoten; Ko Willems-Van Dijk; Philip de Groot; Michael Müller; Edwin Mariman; Egbert Smit
Short-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice.
Physiological genomics 2008;32(3):360-9.
2008: Mark Bouwens; Lydia A Afman; Michael Müller
Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response.
BMC genomics 2008;9():262.
2008: Heleen M de Vogel-van den Bosch; Meike Bünger; Philip J de Groot; Hanneke Bosch-Vermeulen; Guido J E J Hooiveld; Michael Müller
PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.
BMC genomics 2008;9():231.
2008: Nicole J W de Wit; Hanneke Bosch-Vermeulen; Philip J de Groot; Guido J E J Hooiveld; Mechteld M Grootte Bromhaar; Jenny Jansen; Michael Müller; Roelof van der Meer
The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice.
BMC medical genomics 2008;1():14.
2008: Linda M Sanderson; Philip J de Groot; Guido J E J Hooiveld; Arjen Koppen; Eric Kalkhoven; Michael Müller; Sander Kersten
Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.
PloS one 2008;3(2):e1681.
2007: Mark Bouwens; Lydia A Afman; Michael Müller
Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells.
The American journal of clinical nutrition 2007;86(5):1515-23.
2007: Eileen F Murphy; Guido J Hooiveld; Michael Müller; Raffaele A Calogero; Kevin D Cashman
Conjugated linoleic acid alters global gene expression in human intestinal-like Caco-2 cells in an isomer-specific manner.
The Journal of nutrition 2007;137(11):2359-65.
2007: Laeticia Lichtenstein; Jimmy F P Berbée; Susan J van Dijk; Ko Willems van Dijk; André Bensadoun; Ido P Kema; Peter J Voshol; Michael Müller; Patrick Rensen; Sander Kersten
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2420-7.
2007: Meike Bünger; Guido J E J Hooiveld; Sander Kersten; Michael Müller
Exploration of PPAR functions by microarray technology--a paradigm for nutrigenomics.
Biochimica et biophysica acta 2007;1771(8):1046-64.
2007: Caroline Duval; Michael Müller; Sander Kersten
PPARalpha and dyslipidemia.
Biochimica et biophysica acta 2007;1771(8):961-71.
2007: Meike Bünger; Heleen M van den Bosch; Jolanda van der Meijde; Sander Kersten; Guido J E J Hooiveld; Michael Müller
Genome-wide analysis of PPARalpha activation in murine small intestine.
Physiological genomics 2007;30(2):192-204.
2007: Marie-Louise Ricketts; Mark V Boekschoten; Arja J Kreeft; Guido J E J Hooiveld; Corina J A Moen; Michael Müller; Rune R Frants; Soemini Kasanmoentalib; Sabine M Post; Hans M G Princen; J Gordon Porter; Martijn B Katan; Marten H Hofker; David D Moore
The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.
Molecular endocrinology (Baltimore, Md.) 2007;21(7):1603-16.
2007: Hans-Georg Joost; Michael J Gibney; Kevin D Cashman; Ulf Görman; John E Hesketh; Michael Mueller; Michael Müller; Christine M Williams; John C Mathers
Personalised nutrition: status and perspectives.
The British journal of nutrition 2007;98(1):26-31.
2007: Rinke Stienstra; Stéphane Mandard; David Patsouris; Cathy Maass; Sander Kersten; Michael Müller
Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation.
Endocrinology 2007;148(6):2753-63.
2007: Stéphane Mandard; Rinke Stienstra; Pascal Escher; Nguan Soon Tan; I Kim; F J Gonzalez; Walter Wahli; Béatrice Desvergne; Michael Müller; Sander Kersten
Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.
Cellular and molecular life sciences : CMLS 2007;64(9):1145-57.
2007: Maria C Busstra; Rob Hartog; Sander Kersten; Michael Müller
Design guidelines for the development of digital nutrigenomics learning material for heterogeneous target groups.
Advances in physiology education 2007;31(1):67-75.
2007: Maryam Rakhshandehroo; Linda M Sanderson; Merja Matilainen; Rinke Stienstra; Carsten Carlberg; Philip J de Groot; Michael Müller; Sander Kersten
Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling.
PPAR research 2007;2007():26839.
2007: Heleen M van den Bosch; Meike Bünger; Philip J de Groot; Jolanda van der Meijde; Guido J E J Hooiveld; Michael Müller
Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting.
BMC genomics 2007;8():267.
2007: Rinke Stienstra; Caroline Duval; Michael Müller; Sander Kersten
PPARs, Obesity, and Inflammation.
PPAR research 2007;2007():95974.
2006: Margaretha van der Deen; Hendrik Marks; B W M Willemse; Dirkje S Postma; Michael Müller; Egbert F Smit; George L Scheffer; Rik J Scheper; Elisabeth G E de Vries; Wim Timens
Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients.
Virchows Archiv : an international journal of pathology 2006;449(6):682-8.
2006: Ingrid P C Krapels; Christl Vermeij-Keers; Michael Müller; Annelies de Klein; Régine P M Steegers-Theunissen
Nutrition and genes in the development of orofacial clefting.
Nutrition reviews 2006;64(6):280-8.
2006: Eileen F Murphy; Christopher Jewell; Guido J Hooiveld; Michael Müller; Kevin D Cashman
Conjugated linoleic acid enhances transepithelial calcium transport in human intestinal-like Caco-2 cells: an insight into molecular changes.
Prostaglandins, leukotrienes, and essential fatty acids 2006;74(5):295-301.
2006: Lydia A Afman; Michael Müller
Nutrigenomics: from molecular nutrition to prevention of disease.
Journal of the American Dietetic Association 2006;106(4):569-76.
2006: David Patsouris; Janardan K Reddy; Michael Müller; Sander Kersten
Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression.
Endocrinology 2006;147(3):1508-16.
2006: Stéphane Mandard; Fokko Zandbergen; Esther van Straten; Walter Wahli; Folkert Kuipers; Michael Müller; Sander Kersten
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
The Journal of biological chemistry 2006;281(2):934-44.
2005: Fokko Zandbergen; Stéphane Mandard; Pascal Escher; Nguan Soon Tan; David Patsouris; Tim Jatkoe; Sandra Rojas-Caro; Steve Madore; Walter Wahli; Sherrie Tafuri; Michael Müller; Sander Kersten
The G0/G1 switch gene 2 is a novel PPAR target gene.
The Biochemical journal 2005;392(Pt 2):313-24.
2005: Jim Kaput; Jose Ordovas; Lynnette Ferguson; Michael Müller; Raymond L Rodriguez; Lindsay Allen; Bruce N Ames; Kevin Dawson; Bruce german; Ronald Krauss; Wasyl Malyj; Michael C Archer; Stephen Barnes; Amelia Bartholomew; Ruth Birk; Peter van Bladeren; Kent J Bradford; Kenneth H Brown; Rosane Caetano; David Castle; Ruth Chadwick; Stephen Clarke; Karine Clément; Craig Cooney; Dolores Corella; Ivana Beatrice Manica da Cruz; Hannelore Daniel; Troy Duster; Sven O E Ebbesson; Ruan Elliott; Susan Fairweather-Tait; Jim Felton; Michael Fenech; John W Finley; Nancy Fogg-Johnson; Rosalynn Gill-Garrison; Michael J Gibney; Peter J Gillies; Jan-Ake Gustafsson; John L Hartman Iv; Lin He; Jae-Kwan Hwang; Jean-Philippe jais; Yangsoo Jang; Hans Joost; Claudine Junien; Mitchell Kanter; Warren A Kibbe; Berthold Koletzko; Bruce Korf; Kenneth Kornman; David W Krempin; Dominique Langin; Denis R Lauren; Jong Ho Lee; Gilbert A Leveille; Su-Ju Lin; John Mathers; Michael Mayne; Warren McNabb; John A Milner; Peter Morgan; Michael Muller; Yuri Nikolsky; Frans van der Ouderaa; Taesun Park; Norma Pensel; Francisco Perez-Jimenez; Kaisa Poutanen; Matthew Roberts; Wim H M Saris; Gertrud Schuster; Andrew N Shelling; Artemis P Simopoulos; Sue Southon; E Shyong Tai; Bradford Towne; Paul Trayhurn; Ricardo Uauy; Willard J Visek; Craig H Warden; Rick Weiss; John Wiencke; Jack Winkler; George Wolff; Xi Zhao-Wilson; Jean-Daniel Zucker
The case for strategic international alliances to harness nutritional genomics for public and personal health.
The British journal of nutrition 2005;94(5):623-32.
2005: Irène Corthésy-Theulaz; Johan T den Dunnen; Pascal Ferré; Jan Geurts; Michael Müller; Nico van Belzen; Michael Müller
Nutrigenomics: the impact of biomics technology on nutrition research.
Annals of nutrition & metabolism 2005;49(6):355-65.
2005: Christian Klein; Torsten Wüstefeld; Ulrike Assmus; Tania Roskams; Stefan Rose-John; Michael Müller; Michael P Manns; Mattias Ernst; Christian Trautwein
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury.
The Journal of clinical investigation 2005;115(4):860-9.
2005: Guus H E Jansen; Ilja C W Arts; Michel W F Nielen; Michael Müller; Peter C H Hollman; Jaap Keijer
Uptake and metabolism of enterolactone and enterodiol by human colon epithelial cells.
Archives of biochemistry and biophysics 2005;435(1):74-82.
2004: David Patsouris; Michael Müller; Sander Kersten
Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance.
Current opinion in investigational drugs (London, England : 2000) 2004;5(10):1045-50.
2004: Stéphane Mandard; Fokko Zandbergen; Nguan Soon Tan; Pascal Escher; David Patsouris; Wolfgang Koenig; Robert Kleemann; Arjen Bakker; Frank Veenman; Walter Wahli; Michael Müller; Sander Kersten
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.
The Journal of biological chemistry 2004;279(33):34411-20.
2004: David Patsouris; Stéphane Mandard; Peter J Voshol; Pascal Escher; Nguan Soon Tan; Louis M Havekes; Wolfgang Koenig; Winfried März; Sherrie Tafuri; Walter Wahli; Michael Müller; Sander Kersten
PPARalpha governs glycerol metabolism.
The Journal of clinical investigation 2004;114(1):94-103.
2004: Rinke Stienstra; Elgin Lichtenauer-Kaligis; Michael Müller
Stress- (and diet-) related regulation of hepatic nuclear receptors and its relevance for ABC-transporter functions.
Drug metabolism reviews 2004;36(2):391-406.
2004: Stéphane Mandard; Michael Müller; Sander Kersten
Peroxisome proliferator-activated receptor alpha target genes.
Cellular and molecular life sciences : CMLS 2004;61(4):393-416.
2004: Jacqueline R M Plass; Olaf Mol; Janette Heegsma; Mariska Geuken; Joost de Bruin; Geeske Elling; Michael Müller; Klaas Nico Faber; Peter L M Jansen
A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump.
Journal of hepatology 2004;40(1):24-30.
2003: Jenny E Ros; Tania Roskams; Mariska Geuken; Rick Havinga; P L Splinter; Bryon E Petersen; N F LaRusso; Dorina M van der Kolk; Folkert Kuipers; Klaas Nico Faber; Michael Müller; Peter L M Jansen
ATP binding cassette transporter gene expression in rat liver progenitor cells.
Gut 2003;52(7):1060-7.
2003: Michael Müller; Sander Kersten
Nutrigenomics: goals and strategies.
Nature reviews. Genetics 2003;4(4):315-22.
2003: Klaas Nico Faber; Michael Müller; Peter L M Jansen
Drug transport proteins in the liver.
Advanced drug delivery reviews 2003;55(1):107-24.
2002: Robbert Cool; Marloes K Veenstra; Wim van Klompenburg; René I R Heyne; Michael Müller; Elisabeth G E de Vries; Hendrik W Van Veen; Wil N Konings
S-decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1).
European journal of biochemistry / FEBS 2002;269(14):3470-8.
2002: Willie M van Waarde; Henkjan J Verkade; Henk Wolters; Rick Havinga; Julius F W Baller; Vincent Bloks; Michael Müller; Pieter J J Sauer; Folkert Kuipers
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats.
Gastroenterology 2002;122(7):1842-52.
2002: Dorina M van der Kolk; Edo Vellenga; George L Scheffer; Michael Müller; Susan E Bates; Rik J Scheper; Elisabeth G E de Vries
Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia.
Blood 2002;99(10):3763-70.
2002: George L Scheffer; Adriana C L M Pijnenborg; E F Smit; Michael Müller; D S Postma; Wim Timens; Paul Van Der Valk; E G E de Vries; Rik J Scheper
Multidrug resistance related molecules in human and murine lung.
Journal of clinical pathology 2002;55(5):332-9.
2002: Dorina M van der Kolk; Elisabeth G E de Vries; Michael Müller; Edo Vellenga
The role of drug efflux pumps in acute myeloid leukemia.
Leukemia & lymphoma 2002;43(4):685-701.
2002: Guido J E J Hooiveld; Janette Heegsma; Jessica E van Montfoort; Peter L M Jansen; Dirk K F Meijer; Michael Müller
Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins.
British journal of pharmacology 2002;135(7):1685-94.
2002: Jacqueline R M Plass; Olaf Mol; Janette Heegsma; Mariska Geuken; Klaas Nico Faber; Peter L M Jansen; Michael Müller
Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
Hepatology (Baltimore, Md.) 2002;35(3):589-96.
2001: Peter L M Jansen; Michael Müller; Ekkehard Sturm
Genes and cholestasis.
Hepatology (Baltimore, Md.) 2001;34(6):1067-74.
2001: Dorina M van der Kolk; Elisabeth G E de Vries; L Noordhoek; Eva van den Berg; M A van der Pol; Michael Müller; Edo Vellenga
Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia.
Leukemia 2001;15(10):1544-53.
2001: Jessica E van Montfoort; Michael Müller; Geny M M Groothuis; Dirk K F Meijer; H Koepsell; Peter J Meier Abt
Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides.
The Journal of pharmacology and experimental therapeutics 2001;298(1):110-5.
2001: Marius C van den Heuvel; Maarten J H Slooff; L Visser; Michael Müller; Koert P de Jong; Sibrand Poppema; Annette S H Gouw
Expression of anti-OV6 antibody and anti-N-CAM antibody along the biliary line of normal and diseased human livers.
Hepatology (Baltimore, Md.) 2001;33(6):1387-93.
2001: Guido J E J Hooiveld; Jessica E van Montfoort; Dirk K F Meijer; Michael Müller
Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;12(4):525-43.
2000: P L Jansen; Michael Müller; F Kuipers
[Bile formation and cholestasis].
Nederlands tijdschrift voor geneeskunde 2000;144(50):2384-91.
2000: J Renes; E E de Vries; Guido J E J Hooiveld; I Krikken; Peter L M Jansen; Michael Müller
Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal.
The Biochemical journal 2000;350 Pt 2():555-61.
2000: Seema Gupta; R Todd Stravitz; William M Pandak; Michael Müller; Z Reno Vlahcevic; Phillip B Hylemon
Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes.
Hepatology (Baltimore, Md.) 2000;32(2):341-7.
2000: Jan Willem Kok; Robert Jan Veldman; Karin Klappe; H Koning; Catalin M Filipeanu; Michael Müller
Differential expression of sphingolipids in MRP1 overexpressing HT29 cells.
International journal of cancer. Journal international du cancer 2000;87(2):172-8.
2000: Peter L M Jansen; Michael Müller
The molecular genetics of familial intrahepatic cholestasis.
Gut 2000;47(1):1-5.
2000: Hendrik W Van Veen; Abelardo Margolles; Michael Müller; Christopher F Higgins; Wil N Konings
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism.
The EMBO journal 2000;19(11):2503-14.
2000: Dorina M van der Kolk; Edo Vellenga; Anneke Y van der Veen; L Noordhoek; Hetty Timmer-Bosscha; Gert Ossenkoppele; R A Raymakers; Michael Müller; Eva van den Berg; Elisabeth G E de Vries
Deletion of the multidrug resistance protein MRP1 gene in acute myeloid leukemia: the impact on MRP activity.
Blood 2000;95(11):3514-9.
2000: Peter L M Jansen; Michael Müller
Genetic cholestasis: lessons from the molecular physiology of bile formation.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000;14(3):233-8.
2000: Michael Müller
Transcriptional control of hepatocanalicular transporter gene expression.
Seminars in liver disease 2000;20(3):323-37.
1999: M Schaefer; Han Roelofsen; Henk Wolters; W J Hofmann; Michael Müller; Folkert Kuipers; W Stremmel; roel vonk
Localization of the Wilson's disease protein in human liver.
Gastroenterology 1999;117(6):1380-5.
1999: Peter L M Jansen; Sandra S Strautnieks; Emmanuel Jacquemin; michelle hadchouel; EM Sokal; Guido J E J Hooiveld; J H Koning; A de Jager-Krikken; Folkert Kuipers; Frans Stellaard; C M A Bijleveld; Annette S H Gouw; Harry van Goor; Richard John Thompson; Michael Müller
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.
Gastroenterology 1999;117(6):1370-9.
1999: Charles O Mills; Piotr Milkiewicz; Michael Müller; Marcelo G Roma; R Havinga; Roger Coleman; F Kuipers; P L Jansen; Elwyn Elias
Different pathways of canalicular secretion of sulfated and non-sulfated fluorescent bile acids: a study in isolated hepatocyte couplets and TR- rats.
Journal of hepatology 1999;31(4):678-84.
1999: Jessica E van Montfoort; Bruno Hagenbuch; Karin Fattinger; Michael Müller; Geny M M Groothuis; Dirk K F Meijer; Peter J Meier Abt
Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations.
The Journal of pharmacology and experimental therapeutics 1999;291(1):147-52.
1999: L Meerman; NR Koopen; Vincent Bloks; Harry van Goor; Rick Havinga; B G Wolthers; Werner Kramer; Siegfried Stengelin; Michael Müller; Folkert Kuipers; Peter L M Jansen
Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria.
Gastroenterology 1999;117(3):696-705.
1999: Guido J E J Hooiveld; TA Vos; G L Scheffer; Harry van Goor; H Koning; Vincent Bloks; Annemarieke E Loot; Dirk K F Meijer; Peter L M Jansen; Folkert Kuipers; Michael Müller
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats.
Gastroenterology 1999;117(3):678-87.
1999: TA Vos; Jenny E Ros; Rick Havinga; Han Moshage; Folkert Kuipers; Peter L M Jansen; Michael Müller
Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats.
Hepatology (Baltimore, Md.) 1999;29(6):1833-9.
1999: Edo Vellenga; LM Tuyt; B J Wierenga; Michael Müller; Wim H A Dokter
Interleukin-6 production by activated human monocytic cells is enhanced by MK-571, a specific inhibitor of the multi-drug resistance protein-1.
British journal of pharmacology 1999;127(2):441-8.
1999: Han Roelofsen; Guido J E J Hooiveld; H Koning; Rick Havinga; Peter L M Jansen; Michael Müller
Glutathione S-conjugate transport in hepatocytes entering the cell cycle is preserved by a switch in expression from the apical MRP2 to the basolateral MRP1 transporting protein.
Journal of cell science 1999;112 ( Pt 9)():1395-404.
1999: J Renes; Elisabeth G E de Vries; EF Nienhuis; Peter L M Jansen; Michael Müller
ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.
British journal of pharmacology 1999;126(3):681-8.
1999: P L Jansen; Michael Müller
Early events in sepsis-associated cholestasis.
Gastroenterology 1999;116(2):486-8.
1999: Dirk K F Meijer; J W Smit; Guido J E J Hooiveld; Jessica E van Montfoort; Peter L M Jansen; Michael Müller
The molecular basis for hepatobiliary transport of organic cations and organic anions.
Pharmaceutical biotechnology 1999;12():89-157.
1999: Dorina M van der Kolk; Edo Vellenga; Michael Müller; Elisabeth G E de Vries
Multidrug resistance protein MRP1, glutathione, and related enzymes. Their importance in acute myeloid leukemia.
Advances in experimental medicine and biology 1999;457():187-98.
1998: TA Vos; Guido J E J Hooiveld; H Koning; S Childs; Dirk K F Meijer; Han Moshage; Peter L M Jansen; Michael Müller
Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver.
Hepatology (Baltimore, Md.) 1998;28(6):1637-44.
1998: NR Koopen; Michael Müller; roel vonk; P Zimniak; Folkert Kuipers
Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation.
Biochimica et biophysica acta 1998;1408(1):1-17.
1998: Dorina M van der Kolk; Elisabeth G E de Vries; J A Koning; Eva van den Berg; Michael Müller; Edo Vellenga
Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(7):1727-36.
1998: Peter L M Jansen; Michael Müller
Progressive familial intrahepatic cholestasis types 1, 2, and 3.
Gut 1998;42(6):766-7.
1998: JW Smit; AH Schinkel; Michael Müller; Betty Weert; Dirk K F Meijer
Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption.
Hepatology (Baltimore, Md.) 1998;27(4):1056-63.
1998: M J Van Luyn; Michael Müller; J Renes; Chris J L M Meijer; Rik J Scheper; EF Nienhuis; Nanno H Mulder; Peter L M Jansen; Elisabeth G E de Vries
Transport of glutathione conjugates into secretory vesicles is mediated by the multidrug-resistance protein 1.
International journal of cancer. Journal international du cancer 1998;76(1):55-62.
1998: Michael Müller; Peter L M Jansen
The secretory function of the liver: new aspects of hepatobiliary transport.
Journal of hepatology 1998;28(2):344-54.
1998: NR Koopen; Henk Wolters; Rick Havinga; roel vonk; Peter L M Jansen; Michael Müller; Folkert Kuipers
Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.
Hepatology (Baltimore, Md.) 1998;27(2):537-45.
1997: M Bakker; J Renes; A Groenhuijzen; P Visser; Hetty Timmer-Bosscha; Michael Müller; H J Groen; Egbert F Smit; Elisabeth G E de Vries
Mechanisms for high methoxymorpholino doxorubicin cytotoxicity in doxorubicin-resistant tumor cell lines.
International journal of cancer. Journal international du cancer 1997;73(3):362-6.
1997: NR Koopen; Henk Wolters; Michael Müller; IJ Schippers; Rick Havinga; Han Roelofsen; roel vonk; Bruno Stieger; Peter Meier; Folkert Kuipers
Hepatic bile salt flux does not modulate level and activity of the sinusoidal Na+-taurocholate cotransporter (ntcp) in rats.
Journal of hepatology 1997;27(4):699-706.
1997: H Roelofsen; Michael Müller; Peter L M Jansen
Regulation of organic anion transport in the liver.
The Yale journal of biology and medicine 1997;70(4):435-45.
1997: IJ Schippers; Han Moshage; Han Roelofsen; Michael Müller; H S Heymans; Marcel H J Ruiters; Folkert Kuipers
Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation.
Cell biology and toxicology 1997;13(4-5):375-86.
1997: Michael Müller; Peter L M Jansen
Molecular aspects of hepatobiliary transport.
The American journal of physiology 1997;272(6 Pt 1):G1285-303.
1997: J Asschert; E de Vries; Dorina M van der Kolk; Michael Müller; Edo Vellenga
The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines.
Leukemia 1997;11(5):680-6.
1997: Han Roelofsen; TA Vos; IJ Schippers; Folkert Kuipers; H Koning; Han Moshage; Peter L M Jansen; Michael Müller
Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells.
Gastroenterology 1997;112(2):511-21.
1996: Michael Müller; Han Roelofsen; Peter L M Jansen
Secretion of organic anions by hepatocytes: involvement of homologues of the multidrug resistance protein.
Seminars in liver disease 1996;16(2):211-20.
1996: X Bossuyt; Michael Müller; Bruno Hagenbuch; Peter J Meier Abt
Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver.
The Journal of pharmacology and experimental therapeutics 1996;276(3):891-6.
1996: Michael Müller; Elisabeth G E de Vries; Peter L M Jansen
Role of multidrug resistance protein (MRP) in glutathione S-conjugate transport in mammalian cells.
Journal of hepatology 1996;24 Suppl 1():100-8.
1995: E G de Vries; Michael Müller; C Meijer; P L Jansen; N H Mulder
Role of the glutathione S-conjugate pump in cisplatin resistance.
Journal of the National Cancer Institute 1995;87(7):537-8.
1995: Simonetta Nicosia; Valérie Capra; D Ragnini; S Giovanazzi; Maurizio Mezzetti; D Keppler; Michael Müller; G Enrico Rovati
Receptors for cys-leukotrienes in human lung parenchyma: characterization by computer modelling and photoaffinity labelling of binding sites.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():267-9.
1994: Michael Müller; C Meijer; G J Zaman; P Borst; Rik J Scheper; N H Mulder; Elisabeth G E de Vries; Peter L M Jansen
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):13033-7.
1994: M Böhme; Michael Müller; Inka Leier; Gabriele Jedlitschky; Dietrich Keppler
Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver.
Gastroenterology 1994;107(1):255-65.
1994: Michael Müller; R Mayer; U Hero; Dietrich Keppler
ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein.
FEBS letters 1994;343(2):168-72.
1993: M Böhme; M Büchler; Michael Müller; Dietrich Keppler
Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane.
FEBS letters 1993;333(1-2):193-6.
1992: Inka Leier; Michael Müller; Gabriele Jedlitschky; Dietrich Keppler
Leukotriene uptake by hepatocytes and hepatoma cells.
European journal of biochemistry / FEBS 1992;209(1):281-9.
1992: W E Mol; Michael Müller; G Kurz; Dirk K F Meijer
Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide ethobromide.
Biochemical pharmacology 1992;43(10):2217-26.
1992: Dietrich Keppler; Michael Müller; C Klünemann; A Guhlmann; K Krauss; J Müller; U Berger; Inka Leier; Ertan Mayatepek
Transport and in vivo elimination of cysteinyl leukotrienes.
Advances in enzyme regulation 1992;32():107-16.
1991: Gabriele Jedlitschky; M Huber; Alfred Völkl; Michael Müller; Inka Leier; J Müller; W D Lehmann; H D Fahimi; Dietrich Keppler
Peroxisomal degradation of leukotrienes by beta-oxidation from the omega-end.
The Journal of biological chemistry 1991;266(36):24763-72.
1991: Michael Müller; T Ishikawa; U Berger; C Klünemann; Lothar Lucka; A Schreyer; Christoph Kannicht; Werner Reutter; G Kurz; Dietrich Keppler
ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt.
The Journal of biological chemistry 1991;266(28):18920-6.
1991: Michael Müller; E Falk; R Sandbrink; U Berger; Inka Leier; Gabriele Jedlitschky; M Huber; G Kurz; Dietrich Keppler
Photoaffinity labeling of leukotriene binding sites in hepatocytes and hepatoma cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():395-8.
1990: T Ishikawa; Michael Müller; C Klünemann; T Schaub; Dietrich Keppler
ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates.
The Journal of biological chemistry 1990;265(31):19279-86.
1990: Dirk K F Meijer; W E Mol; Michael Müller; G Kurz
Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations.
Journal of pharmacokinetics and biopharmaceutics 1990;18(1):35-70.
1988: H P Buscher; W Gerok; M Köllinger; G Kurz; Michael Müller; A Nolte; S Schneider
Transport systems for amphipathic compounds in normal and neoplastic hepatocytes.
Advances in enzyme regulation 1988;27():173-92.