Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Hugues BEDOUELLE
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Living Beings
Concepts & Ideas
Genes & Molecular Sequences
Physiology
Sign-in to see full Profile
Network (preview)
7
England, Patrick
6
Guez, Valérie
5
Hofnung, Maurice
5
Renard, Martial
4
Rondard, P
4
Belkadi, Laurent
4
Thullier, Philippe
4
DELEPIERRE, Muriel
3
Brégégère, F
2
Guijarro, Iñaki
2
Pintar, Alessandro
2
Monsellier, Elodie
2
Fersht, Alan
1
Beckwith, Jonathan R.
1
Altschuh, Danièle
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Hugues BEDOUELLE (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Hershkovitz Oren; Rosental Benyamin; Rosenberg Lior Ann; Navarro-Sanchez Martha Erika; Jivov Sergey; Zilka Alon; Gershoni-Yahalom Orly; Brient-Litzler Elodie; Bedouelle Hugues; Ho Joanna W; Campbell Kerry S; Rager-Zisman Bracha; Despres Philippe; Porgador Angel
NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2610-21.
-
2008: Pelat Thibaut; Bedouelle Hugues; Rees Anthony R; Crennell Susan J; Lefranc Marie-Paule; Thullier Philippe
Germline humanization of a non-human primate antibody that neutralizes the anthrax toxin, by in vitro and in silico engineering.
Journal of molecular biology 2008;384(5):1400-7.
-
2008: Laffly Emmanuelle; Pelat Thibaut; Cédrone Frédéric; Blésa Stéphane; Bedouelle Hugues; Thullier Philippe
Improvement of an antibody neutralizing the anthrax toxin by simultaneous mutagenesis of its six hypervariable loops.
Journal of molecular biology 2008;378(5):1094-103.
-
2007: Lisova Olesia; Hardy Florence; Petit Vincent; Bedouelle Hugues
Mapping to completeness and transplantation of a group-specific, discontinuous, neutralizing epitope in the envelope protein of dengue virus.
The Journal of general virology 2007;88(Pt 9):2387-97.
-
2007: Brandler Samantha; Lucas-Hourani Marianne; Moris Arnaud; Frenkiel Marie-Pascale; Combredet Chantal; Février Michèle; Bedouelle Hugues; Schwartz Olivier; Desprès Philippe; Tangy Frédéric
Pediatric Measles Vaccine Expressing a Dengue Antigen Induces Durable Serotype-specific Neutralizing Antibodies to Dengue Virus.
PLoS neglected tropical diseases 2007;1(3):e96.
-
2006: Monsellier Elodie; Bedouelle Hugues
Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: validation and mechanisms.
Journal of molecular biology 2006;362(3):580-93.
-
2006: Bedouelle Hugues; Belkadi Laurent; England Patrick; Guijarro J Iñaki; Lisova Olesia; Urvoas Agathe; Delepierre Muriel; Thullier Philippe
Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus.
The FEBS journal 2006;273(1):34-46.
-
2005: Monsellier Elodie; Bedouelle Hugues
Quantitative measurement of protein stability from unfolding equilibria monitored with the fluorescence maximum wavelength.
Protein engineering, design & selection : PEDS 2005;18(9):445-56.
-
2004: Renard Martial; Bedouelle Hugues
Improving the sensitivity and dynamic range of reagentless fluorescent immunosensors by knowledge-based design.
Biochemistry 2004;43(49):15453-62.
-
2003: Renard Martial; Belkadi Laurent; Bedouelle Hugues
Deriving topological constraints from functional data for the design of reagentless fluorescent immunosensors.
Journal of molecular biology 2003;326(1):167-75.
-
2002: Bedouelle Hugues; Renard Martial; Belkadi Laurent; England Patrick
Harnessing malE for the study of antigen/antibody recognitions.
Research in microbiology 2002;153(7):395-8.
-
2002: Renard Martial; Belkadi Laurent; Hugo Nicolas; England Patrick; Altschuh Danièle; Bedouelle Hugues
Knowledge-based design of reagentless fluorescent biosensors from recombinant antibodies.
Journal of molecular biology 2002;318(2):429-42.
-
2002: Guijarro J Iñaki; Pintar Alessandro; Prochnicka-Chalufour Ada; Guez Valérie; Gilquin Bernard; Bedouelle Hugues; Delepierre Muriel
Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase.
Structure (London, England : 1993) 2002;10(3):311-7.
-
2001: Thullier P; Demangel C; Bedouelle H; Mégret F; Jouan A; Deubel V; Mazié J C; Lafaye P
Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism.
The Journal of general virology 2001;82(Pt 8):1885-92.
-
2001: Gaillard C; Bedouelle H
An essential residue in the flexible peptide linking the two idiosynchratic domains of bacterial tyrosyl-tRNA synthetases.
Biochemistry 2001;40(24):7192-9.
-
2000: Rondard P; Bedouelle H
Mutational scanning of a hairpin loop in the tryptophan synthase beta-subunit implicated in allostery and substrate channeling.
Biological chemistry 2000;381(12):1185-93.
-
2000: Guez V; Nair S; Chaffotte A; Bedouelle H
The anticodon-binding domain of tyrosyl-tRNA synthetase: state of folding and origin of the crystallographic disorder.
Biochemistry 2000;39(7):1739-47.
-
1999: Jermutus L; Guez V; Bedouelle H
Disordered C-terminal domain of tyrosyl-tRNA synthetase: secondary structure prediction.
Biochimie 1999;81(3):235-44.
-
1999: Pintar A; Guez V; Castagné C; Bedouelle H; Delepierre M
Secondary structure of the C-terminal domain of the tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus: a novel type of anticodon binding domain?
FEBS letters 1999;446(1):81-5.
-
1999: Park Y C; Guez V; Bedouelle H
Experimental evolution of a dense cluster of residues in tyrosyl-tRNA synthetase: quantitative effects on activity, stability and dimerization.
Journal of molecular biology 1999;286(2):563-77.
-
1999: England P; Nageotte R; Renard M; Page A L; Bedouelle H
Functional characterization of the somatic hypermutation process leading to antibody D1.3, a high affinity antibody directed against lysozyme.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2129-36.
-
1998: Rondard P; Bedouelle H
A mutational approach shows similar mechanisms of recognition for the isolated and integrated versions of a protein epitope.
The Journal of biological chemistry 1998;273(52):34753-9.
-
1998: Guermonprez P; England P; Bedouelle H; Leclerc C
The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4542-8.
-
1998: Park Y C; Bedouelle H
Dimeric tyrosyl-tRNA synthetase from Bacillus stearothermophilus unfolds through a monomeric intermediate. A quantitative analysis under equilibrium conditions.
The Journal of biological chemistry 1998;273(29):18052-9.
-
1997: Brégégère F; England P; Djavadi-Ohaniance L; Bedouelle H
Recognition of E. coli tryptophan synthase by single-chain Fv fragments: comparison of PCR-cloning variants with the parental antibodies.
Journal of molecular recognition : JMR 1997;10(4):169-81.
-
1997: Rondard P; Goldberg M E; Bedouelle H
Mutational analysis of an antigenic peptide shows recognition in a loop conformation.
Biochemistry 1997;36(29):8962-8.
-
1997: Rondard P; Brégégère F; Lecroisey A; Delepierre M; Bedouelle H
Conformational and functional properties of an undecapeptide epitope fused with the C-terminal end of the maltose binding protein.
Biochemistry 1997;36(29):8954-61.
-
1997: England P; Brégégère F; Bedouelle H
Energetic and kinetic contributions of contact residues of antibody D1.3 in the interaction with lysozyme.
Biochemistry 1997;36(1):164-72.
-
1996: Blondel A; Nageotte R; Bedouelle H
Destabilizing interactions between the partners of a bifunctional fusion protein.
Protein engineering 1996;9(2):231-8.
-
1996: Guez-Ivanier V; Bedouelle H
Disordered C-terminal domain of tyrosyl transfer-RNA synthetase: evidence for a folded state.
Journal of molecular biology 1996;255(1):110-20.
-
1995: Bedouelle H; Nageotte R
Macromolecular recognition through electrostatic repulsion.
The EMBO journal 1995;14(12):2945-50.
-
1994: Brégégère F; Schwartz J; Bedouelle H
Bifunctional hybrids between the variable domains of an immunoglobulin and the maltose-binding protein of Escherichia coli: production, purification and antigen binding.
Protein engineering 1994;7(2):271-80.
-
1993: Guez-Ivanier V; Hermann M; Baldwin D; Bedouelle H
Mapping the stability determinants of bacterial tyrosyl transfer RNA synthetases by an experimental evolutionary approach.
Journal of molecular biology 1993;234(1):209-21.
-
1993: Bedouelle H
Symmetrical interactions between the translational operator of the thrS gene and dimeric threonyl transfer RNA synthetase.
Journal of molecular biology 1993;230(3):704-8.
-
1993: Bedouelle H; Guez-Ivanier V; Nageotte R
Discrimination between transfer-RNAs by tyrosyl-tRNA synthetase.
Biochimie 1993;75(12):1099-108.
-
1992: Vidal-Cros A; Bedouelle H
Role of residue Glu152 in the discrimination between transfer RNAs by tyrosyl-tRNA synthetase from Bacillus stearothermophilus.
Journal of molecular biology 1992;223(3):801-10.
-
1992: Brégégère F; Bedouelle H
[Expression, isolation and purification of antibody fragments fused to maltose-binding protein in Escherichia coli]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;314(12):527-32.
-
1991: Blondel A; Bedouelle H
Engineering the quaternary structure of an exported protein with a leucine zipper.
Protein engineering 1991;4(4):457-61.
-
1990: Blondel A; Bedouelle H
Export and purification of a cytoplasmic dimeric protein by fusion to the maltose-binding protein of Escherichia coli.
European journal of biochemistry / FEBS 1990;193(2):325-30.
-
1990: Bedouelle H
Recognition of tRNA(Tyr) by tyrosyl-tRNA synthetase.
Biochimie 1990;72(8):589-98.
-
1990: Bedouelle H; Guez V; Vidal-Cros A; Hermann M
Overproduction of tyrosyl-tRNA synthetase is toxic to Escherichia coli: a genetic analysis.
Journal of bacteriology 1990;172(7):3940-5.
-
1990: Hermann M; Bedouelle H
A method for monitoring double restriction cuts within a polylinker.
Research in microbiology 1990;141(2):187-9.
-
1989: Labouze E; Bedouelle H
Structural and kinetic bases for the recognition of tRNATyr by tyrosyl-tRNA synthetase.
Journal of molecular biology 1989;205(4):729-35.
-
1988: Fersht A R; Knill-Jones J W; Bedouelle H; Winter G
Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism.
Biochemistry 1988;27(5):1581-7.
-
1988: Bedouelle H; Duplay P
Production in Escherichia coli and one-step purification of bifunctional hybrid proteins which bind maltose. Export of the Klenow polymerase into the periplasmic space.
European journal of biochemistry / FEBS 1988;171(3):541-9.
-
1987: Duplay P; Szmelcman S; Bedouelle H; Hofnung M
Silent and functional changes in the periplasmic maltose-binding protein of Escherichia coli K12. I. Transport of maltose.
Journal of molecular biology 1987;194(4):663-73.
-
1987: Bedouelle H; Duplay P; Hofnung M
[Expression, export and one-step purification of proteins by fusion to the MalE protein of E. coli]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1987;305(17):623-6.
-
1986: Bedouelle H; Winter G
A model of synthetase/transfer RNA interaction as deduced by protein engineering.
Nature 1986;320(6060):371-3.
-
1986: Carter P; Bedouelle H; Winter G
Construction of heterodimer tyrosyl-tRNA synthetase shows tRNATyr interacts with both subunits.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(5):1189-92.
-
1985: Bedouelle H; Carter P; Waye M M; Winter G; Lowe D M; Wilkinson A J; Fersht A R
Engineering of tyrosyl tRNA synthetase.
Biochimie 1985;67(7-8):737-43.
-
1985: Duplay P; Bedouelle H; Szmelcman S; Hofnung M
Linker mutagenesis in the gene encoding the periplasmic maltose-binding protein of E. coli.
Biochimie 1985;67(7-8):849-51.
-
1985: Carter P; Bedouelle H; Winter G
Improved oligonucleotide site-directed mutagenesis using M13 vectors.
Nucleic acids research 1985;13(12):4431-43.
-
1984: Duplay P; Bedouelle H; Fowler A; Zabin I; Saurin W; Hofnung M
Sequences of the malE gene and of its product, the maltose-binding protein of Escherichia coli K12.
The Journal of biological chemistry 1984;259(16):10606-13.
-
1983: Bedouelle H
Mutations in the promoter regions of the malEFG and malK-lamB operons of Escherichia coli K12.
Journal of molecular biology 1983;170(4):861-82.
-
1982: Bedouelle H; Schmeissner U; Hofnung M; Rosenberg M
Promoters of the malEFG and malK-lamB operons in Escherichia coli K12.
Journal of molecular biology 1982;161(4):519-31.
-
1982: Bedouelle H
Structure of the malB regulatory interval.
Annales de microbiologie 1982;133A(1):65-70.
-
1982: Bedouelle H; Hofnung M
A DNA sequence containing the control regions of the malEFG and malK-lamB operons in Escherichia coli K12.
Molecular & general genetics : MGG 1982;185(1):82-7.
-
1981: Bedouelle H; Hofnung M
Functional implications of secondary structure analysis of wild type and mutant bacterial signal peptides.
Progress in clinical and biological research 1981;63():399-403.
-
1980: Bedouelle H; Bassford P J; Fowler A V; Zabin I; Beckwith J; Hofnung M
Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli.
Nature 1980;285(5760):78-81.
-
1980: Hermann M; Chaudé O; Weill N; Bedouelle H; Hofnung M
Adaptation of the salmonella/mammalian microsome test to the determination of the mutagenic properties of mineral oils.
Mutation research 1980;77(4):327-39.
-
1978: Bedouelle H; Hofnung M
[Short term tests of carcinogenesis. Evaluation, predictive values, and diverse strategies]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1978;287(9):891-4.
Sign-in to see more
