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Jonas Perales

Research Profile

Chemicals & Drugs

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Amino Acid Sequences

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Germana Bueno Dias; Kátia Valevski Sales Fernandes; André Teixeira S Ferreira; Valdirene M Gomes; Olga L T Machado; Jonas Perales; Umberto Zottich Pereira; Suzanna F Ferreira Ribeiro; Rosana Rodrigues; André O Carvalho; Maura da Cunha
Isolation, characterization and antifungal activity of proteinase inhibitors from Capsicum chinense Jacq. Seeds.
Karina Mastropasqua Rebello; Erika Louise Ribeiro; Richard H Valente; Caroline Reis de Siqueira; Ester Maria Mota; Ana G C Neves-Ferreira; Jonas Perales; Henrique Leonel Lenzi
Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis.
Ileana R León; Jonas Perales; Ana Gisele da Costa Neves-Ferreira; Monique Ramos de Oliveira Trugilho; Surza Lucia Gonçalves da Rocha; Richard H Valente
Using mass spectrometry to explore the neglected glycan moieties of the antiophidic proteins DM43 and DM64.

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All Publications

2013: Germana Bueno Dias; Kátia Valevski Sales Fernandes; André Teixeira S Ferreira; Valdirene M Gomes; Olga L T Machado; Jonas Perales; Umberto Zottich Pereira; Suzanna F Ferreira Ribeiro; Rosana Rodrigues; André O Carvalho; Maura da Cunha
Isolation, characterization and antifungal activity of proteinase inhibitors from Capsicum chinense Jacq. Seeds.
The protein journal 2013;32(1):15-26.
2012: Karina Mastropasqua Rebello; Erika Louise Ribeiro; Richard H Valente; Caroline Reis de Siqueira; Ester Maria Mota; Ana G C Neves-Ferreira; Jonas Perales; Henrique Leonel Lenzi
Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis.
Memórias do Instituto Oswaldo Cruz 2012;107(6):752-9.
2012: Ileana R León; Jonas Perales; Ana Gisele da Costa Neves-Ferreira; Monique Ramos de Oliveira Trugilho; Surza Lucia Gonçalves da Rocha; Richard H Valente
Using mass spectrometry to explore the neglected glycan moieties of the antiophidic proteins DM43 and DM64.
Proteomics 2012;12(17):2753-65.
2012: Guilherme D Brand; Gilberto B Domont; Thomas J D Jørgensen; Jonas Perales; Carol V Robinson; Peter Roepstorff; Rune Salbo; Isabelle Tanjoni; Richard H Valente; Ana M Moura-da-Silva; Carlos Bloch; Elisabetta Boeri Erba; Ana G C Neves-Ferreira
The interaction of the antitoxin DM43 with a snake venom metalloproteinase analyzed by mass spectrometry and surface plasmon resonance.
Journal of mass spectrometry : JMS 2012;47(5):567-73.
2012: Paulo C Carvalho; Daniel Cociorva; Juliana S G Fischer; Jonas Perales; Richard H Valente; Tao Xu; John R Yates; Tiago S Balbuena; Valmir C Barbosa
Search engine processor: Filtering and organizing peptide spectrum matches.
Proteomics 2012;12(7):944-9.
2012: Ana T C Ching; Surza L G da Rocha; Maria de Fátima D Furtado; Paulo L Ho; Adriana Paes Leme; Jonas Perales; Marisa M T Rocha; Solange M T Serrano; Débora Andrade Silva; Monique R O Trugilho; André Zelanis; Inácio L M Junqueira-de-Azevedo
Venomics profiling of Thamnodynastes strigatus unveils matrix metalloproteinases and other novel proteins recruited to the toxin arsenal of rear-fanged snakes.
Journal of proteome research 2012;11(2):1152-62.
2012: A J Souza; T M Venancio; José Xavier-Filho; Jonas Perales; D G Beghini; K V S Fernandes; A T S Ferreira; A E A Oliveira
Identification of Albizia lebbeck seed coat chitin-binding vicilins (7S globulins) with high toxicity to the larvae of the bruchid Callosobruchus maculatus.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2012;45(2):118-24.
2011: Karina M Rebello; Jonas Perales; Juliana S L Barros; Paulo C Carvalho; Henrique Leonel Lenzi; Ester Maria Mota; Ana G C Neves-Ferreira
Comprehensive proteomic profiling of adult Angiostrongylus costaricensis, a human parasitic nematode.
Journal of proteomics 2011;74(9):1545-59.
2011: Lilian R Pratt-Riccio; Evelyn Kety Pratt Riccio; Luciene Aquino Silva; Michael Theisen; Paulo Renato Rivas Totino; Cesare Bianco; Surza L G Rocha; Joseli De Oliveira-Ferreira; Leonardo J M Carvalho; Cláudio Tadeu Daniel-Ribeiro; Fabrício Dias-Da-Silva; Vítor Ennes-Vidal; Maria de Fátima Ferreira-da-Cruz; Ana G C Neves-Ferreira; Jonas Perales; Daiana De Souza Perce-Da-Silva; Dalma M Banic
Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth.
Memórias do Instituto Oswaldo Cruz 2011;106 Suppl 1():34-43.
2011: Paulo C Carvalho; Juliana S G Fischer; Jonas Perales; John R Yates; Valmir C Barbosa; Elias Bareinboim
Analyzing marginal cases in differential shotgun proteomics.
Bioinformatics (Oxford, England) 2011;27(2):275-6.
2010: Simone A Kikuchi; Cátia L Sodré; Dário E Kalume; Camila G R Elias; André L S Santos; Maria de Nazaré Soeiro; Marcos B Meuser; Alex Chapeaurouge; Jonas Perales; Octavio Fernandes
Proteomic analysis of two Trypanosoma cruzi zymodeme 3 strains.
Experimental parasitology 2010;126(4):540-51.
2010: Rubem F S Menna-Barreto; Daniela G Beghini; André T S Ferreira; Antônio V Pinto; Solange L de Castro; Jonas Perales
A proteomic analysis of the mechanism of action of naphthoimidazoles in Trypanosoma cruzi epimastigotes in vitro.
Journal of proteomics 2010;73(12):2306-15.
2009: Lidiane M Albuquerque; Monique R O Trugilho; Alex Chapeaurouge; Patrícia B Jurgilas; Patrícia T Bozza; Fernando A Bozza; Jonas Perales; Ana G C Neves-Ferreira
Two-dimensional difference gel electrophoresis (DiGE) analysis of plasmas from dengue fever patients.
Journal of proteome research 2009;8(12):5431-41.
2009: Alex Chapeaurouge; Samantha M Martins; Oliver Holub; Surza L G Rocha; Richard H Valente; Ana G C Neves-Ferreira; Sérgio T Ferreira; Gilberto B Domont; Jonas Perales
Conformational plasticity of DM43, a metalloproteinase inhibitor from Didelphis marsupialis: chemical and pressure-induced equilibrium (un)folding studies.
Biochimica et biophysica acta 2009;1794(10):1379-86.
2009: Surza L G Rocha; Ana G C Neves-Ferreira; Monique R O Trugilho; Alex Chapeaurouge; Ileana R León; Richard H Valente; Gilberto B Domont; Jonas Perales
Crotalid snake venom subproteomes unraveled by the antiophidic protein DM43.
Journal of proteome research 2009;8(5):2351-60.
2009: Richard H Valente; Patrícia R Guimarães; Magno Junqueira; Ana Gisele C Neves-Ferreira; Márcia R Soares; Alex Chapeaurouge; Monique R O Trugilho; Ileana R León; Surza L G Rocha; Ana Lucia Oliveira-Carvalho; Luciana S Wermelinger; Denis L S Dutra; Luciana I Leão; Inácio L M Junqueira-de-Azevedo; Paulo L Ho; Russolina B Zingali; Jonas Perales; Gilberto B Domont
Bothrops insularis venomics: a proteomic analysis supported by transcriptomic-generated sequence data.
Journal of proteomics 2009;72(2):241-55.
2009: Cátia Lacerda Sodré; Alexander D Chapeaurouge; Dário Eluan Kalume; Leila de Mendonça Lima; Jonas Perales; Octavio Fernandes
Proteomic map of Trypanosoma cruzi CL Brener: the reference strain of the genome project.
Archives of microbiology 2009;191(2):177-84.
2009: Elane da Silva Ribeiro; Adriana Ferreira Uchôa; Leonardo Gomes da Silva; Daniela Gois Beghini; Andre Teixeira da Silva Ferreira; Jonas Perales; Tânia Jacinto; K V S Fernandes; José Xavier-Filho; A E A Oliveira
Insulin-binding canavalin is present in Canavalia ensiformis seed coat.
Protein and peptide letters 2009;16(9):1106-11.
2008: Sylvio Botelho-Júnior; César L Siqueira-Júnior; Bruno C Jardim; Olga L T Machado; Ana G C Neves-Ferreira; Jonas Perales; Tânia Jacinto
Trypsin inhibitors in passion fruit (Passiflora f. edulis flavicarpa) leaves: accumulation in response to methyl jasmonate, mechanical wounding, and herbivory.
Journal of agricultural and food chemistry 2008;56(20):9404-9.
2008: Hélida M Andrade; Silvane M F Murta; Alex Chapeaurouge; Jonas Perales; Philippe NIRDE; Alvaro J Romanha
Proteomic analysis of Trypanosoma cruzi resistance to Benznidazole.
Journal of proteome research 2008;7(6):2357-67.
2008: Maria Esther Ricci-Silva; Richard Hemmi Valente; Ileana Rodriguez León; Denise Vilarinho Tambourgi; Oscar Henrique Pereira Ramos; Jonas Perales; Ana Marisa Chudzinski-Tavassi
Immunochemical and proteomic technologies as tools for unravelling toxins involved in envenoming by accidental contact with Lonomia obliqua caterpillars.
Toxicon : official journal of the International Society on Toxinology 2008;51(6):1017-28.
2008: R de Moraes; R H Valente; Ileana R León; M R O Trugilho; Antonio Nobrega; Jonas Perales; Eduardo Tibiriçá
Chronic dynamic exercise increases apolipoprotein A-I expression in rabbit renal cortex as determined by proteomic technology.
British journal of sports medicine 2008;42(5):386-8.
2008: Leticia M S Lery; Ana Coelho; Wanda M A von Kruger; Mayla S M Gonçalves; Marise F Santos; Richard H Valente; Eidy O Santos; Surza L G Rocha; Jonas Perales; Gilberto B Domont; Katia R S Teixeira; Marcelo Bertalan; Paulo C G Ferreira; Paulo M Bisch
Protein expression profile of Gluconacetobacter diazotrophicus PAL5, a sugarcane endophytic plant growth-promoting bacterium.
Proteomics 2008;8(8):1631-44.
2008: C Baldo; Isabelle Tanjoni; Ileana R León; Isabel Fátima Correia Batista; Maisa S Della-Casa; Patricia Bianca Clissa; Ricardo Weinlich; Mônica Lopes-Ferreira; I Lebrun; Gustavo Amarante-Mendes; V M Rodrigues; Jonas Perales; Richard H Valente; Ana Maria Moura da Silva
BnP1, a novel P-I metalloproteinase from Bothrops neuwiedi venom: biological effects benchmarking relatively to jararhagin, a P-III SVMP.
Toxicon : official journal of the International Society on Toxinology 2008;51(1):54-65.
2007: V L F Cunha Bastos; João Bosco Salles; Richard H Valente; Ileana R León; Jonas Perales; R F Dantas; R M Albano; F F Bastos; Jayme Cunha-Bastos
Cytosolic glutathione peroxidase from liver of pacu (Piaractus mesopotamicus), a hypoxia-tolerant fish of the Pantanal.
Biochimie 2007;89(11):1332-42.
2007: Ileana R León; Ana G C Neves-Ferreira; Richard H Valente; Ester Maria Mota; Henrique Leonel Lenzi; Jonas Perales
Improved protein identification efficiency by mass spectrometry using N-terminal chemical derivatization of peptides from Angiostrongylus costaricensis, a nematode with unknown genome.
Journal of mass spectrometry : JMS 2007;42(10):1363-74.
2007: Izabela S Santos; A E A Oliveira; Maura da Cunha; Olga L T Machado; Ana G C Neves-Ferreira; K V S Fernandes; André O Carvalho; Jonas Perales; Valdirene M Gomes
Expression of chitinase in Adenanthera pavonina seedlings.
Physiologia plantarum 2007;131(1):80-8.
2007: Ileana R León; Ana G C Neves-Ferreira; Richard H Valente; Ester Maria Mota; Henrique Leonel Lenzi; Jonas Perales
Improved protein identification efficiency by mass spectrometry using N-terminal chemical derivatization of peptides from Angiostrongylus costaricensis, a nematode with unknown genome.
Journal of mass spectrometry : JMS 2007;42(6):781-92.
2007: Diana Bahia; Nelder F Gontijo; Ileana R León; Jonas Perales; Marcos Horácio Pereira; Guilherme Oliveira; Rodrigo Corrêa-Oliveira; Alexandre Barbosa Reis
Antibodies from dogs with canine visceral leishmaniasis recognise two proteins from the saliva of Lutzomyia longipalpis.
Parasitology research 2007;100(3):449-54.
2007: Priscilla Oliveira-Silva; Patricia B Jurgilas; Pablo Trindade; Paula Campello-Costa; Jonas Perales; Wilson Savino; Claudio A Serfaty
Matrix metalloproteinase-9 is involved in the development and plasticity of retinotectal projections in rats.
Neuroimmunomodulation 2007;14(3-4):144-9.
2006: Mariângela S S Diz; André O Carvalho; Rosana Rodrigues; Ana G C Neves-Ferreira; Maura da Cunha; Elias W Alves; Anna L Okorokova-Façanha; Marco Antônio Oliveira; Jonas Perales; Olga L T Machado; Valdirene M Gomes
Antimicrobial peptides from chili pepper seeds causes yeast plasma membrane permeabilization and inhibits the acidification of the medium by yeast cells.
Biochimica et biophysica acta 2006;1760(9):1323-32.
2006: Andre Gustavo Bonavita; Aline S da Costa; Ana Lúcia Aguiar Pires; Ana G C Neves-Ferreira; Jonas Perales; Renato S B Cordeiro; Marco A Martins; Patrícia M R e Silva
Contribution of mast cells and snake venom metalloproteinases to the hyperalgesia induced by Bothrops jararaca venom in rats.
Toxicon : official journal of the International Society on Toxinology 2006;47(8):885-93.
2006: Wanda Maria Almeida von Krüger; Leticia Miranda Santos Lery; Marcia Regina Soares; Fernanda Saloum de Neves-Manta; Celia Maria Batista e Silva; Ana G C Neves-Ferreira; Jonas Perales; Paulo M Bisch
The phosphate-starvation response in Vibrio cholerae O1 and phoB mutant under proteomic analysis: disclosing functions involved in adaptation, survival and virulence.
Proteomics 2006;6(5):1495-511.
2005: Jonas Perales; Ana G C Neves-Ferreira; Richard H Valente; Gilberto B Domont
Natural inhibitors of snake venom hemorrhagic metalloproteinases.
Toxicon : official journal of the International Society on Toxinology 2005;45(8):1013-20.
2005: Jeanne Claíne de Albuquerque Modesto; Inácio L M Junqueira-de-Azevedo; Ana G C Neves-Ferreira; Márcio Fritzen; Maria Luiza V Oliva; Paulo Lee Ho; Jonas Perales; Ana Marisa Chudzinski-Tavassi
Insularinase A, a prothrombin activator from Bothrops insularis venom, is a metalloprotease derived from a gene encoding protease and disintegrin domains.
Biological chemistry 2005;386(6):589-600.
2004: Ana G C Neves-Ferreira; Carlos M de Andrade; Marcos André Vannier-Santos; Jonas Perales; Hilton J Nascimento; José G da Silva Junior
Complete amino acid sequence and location of Omp-28, an important immunogenic protein from Salmonella enterica serovar typhi.
The protein journal 2004;23(1):71-7.
2003: Patrícia B Jurgilas; Ana G C Neves-Ferreira; Gilberto B Domont; Jonas Perales
PO41, a snake venom metalloproteinase inhibitor isolated from Philander opossum serum.
Toxicon : official journal of the International Society on Toxinology 2003;42(6):621-8.
2002: Surza L G Rocha; Bruno Lomonte; Ana G C Neves-Ferreira; Monique R O Trugilho; Inácio de L M Junqueira de Azevedo; Paulo Lee Ho; Gilberto B Domont; José M Gutiérrez; Jonas Perales
Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum.
European journal of biochemistry / FEBS 2002;269(24):6052-62.
2002: Ana G C Neves-Ferreira; Jonas Perales; Jay W Fox; John D Shannon; Débora L Makino; Richard C Garratt; Gilberto B Domont
Structural and functional analyses of DM43, a snake venom metalloproteinase inhibitor from Didelphis marsupialis serum.
The Journal of biological chemistry 2002;277(15):13129-37.
2001: Richard H Valente; Bojan Dragulev; Jonas Perales; Jay W Fox; Gilberto B Domont
BJ46a, a snake venom metalloproteinase inhibitor. Isolation, characterization, cloning and insights into its mechanism of action.
European journal of biochemistry / FEBS 2001;268(10):3042-52.
2000: Surza L G Rocha; Válber S Frutuoso; Gilberto B Domont; Marco A Martins; H Moussatché; Jonas Perales
Inhibition of the hyperalgesic activity of Bothrops jararaca venom by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum.
Toxicon : official journal of the International Society on Toxinology 2000;38(6):875-80.
2000: Ana G C Neves-Ferreira; N Cardinale; Surza L G Rocha; Jonas Perales; Gilberto B Domont
Isolation and characterization of DM40 and DM43, two snake venom metalloproteinase inhibitors from Didelphis marsupialis serum.
Biochimica et biophysica acta 2000;1474(3):309-20.
1999: Ana G C Neves-Ferreira; Richard H Valente; P G Sá; Surza L G Rocha; H Moussatché; Gilberto B Domont; Jonas Perales
New methodology for the obtainment of antibothropic factors from the South American opossum (Didelphis marsupialis) and jararaca snake (Bothrops jararaca).
Toxicon : official journal of the International Society on Toxinology 1999;37(10):1417-29.
1999: P B Jurgilas; Ana G C Neves-Ferreira; Gilberto B Domont; H Moussatché; Jonas Perales
Detection of an antibothropic fraction in opossum (Didelphis marsupialis) milk that neutralizes Bothrops jararaca venom.
Toxicon : official journal of the International Society on Toxinology 1999;37(1):167-72.
1997: Ana G C Neves-Ferreira; Jonas Perales; M Ovadia; H Moussatché; Gilberto B Domont
Inhibitory properties of the antibothropic complex from the South American opossum (Didelphis marsupialis) serum.
Toxicon : official journal of the International Society on Toxinology 1997;35(6):849-63.
1996: M F Farah; M One; José Camillo Novello; Marcos H Toyama; Jonas Perales; H Moussatché; Gilberto B Domont; B Oliveira; Sérgio Marangoni
Isolation of protein factors from opossum (Didelphis albiventris) serum which protect against Bothrops jararaca venom.
Toxicon : official journal of the International Society on Toxinology 1996;34(9):1067-71.
1995: Jonas Perales; C Villela; Gilberto B Domont; Valérie Choumet; B Saliou; H Moussatché; Cassian Bon; G Faure
Molecular structure and mechanism of action of the crotoxin inhibitor from Crotalus durissus terrificus serum.
European journal of biochemistry / FEBS 1995;227(1-2):19-26.
1994: Jonas Perales; H Moussatché; Sérgio Marangoni; B Oliveira; Gilberto B Domont
Isolation and partial characterization of an anti-bothropic complex from the serum of South American Didelphidae.
Toxicon : official journal of the International Society on Toxinology 1994;32(10):1237-49.
1993: Patrícia T Bozza; Hugo C Castro-Faria-Neto; M A Martins; Andréa P Larangeira; Jonas Perales; Patrícia M R e Silva; Renato S B Cordeiro
Pharmacological modulation of lipopolysaccharide-induced pleural eosinophilia in the rat; a role for a newly generated protein.
European journal of pharmacology 1993;248(1):41-7.
1992: Jonas Perales; C Z Amorim; S L Rocha; Gilberto B Domont; H Moussatché
Neutralization of the oedematogenic activity of Bothrops jararaca venom on the mouse paw by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum.
Agents and actions 1992;37(3-4):250-9.
1991: Gilberto B Domont; Jonas Perales; H Moussatché
Natural anti-snake venom proteins.
Toxicon : official journal of the International Society on Toxinology 1991;29(10):1183-94.
1989: Jonas Perales; R Muños; S Graterol; O Oviedo; H Moussatché
New findings on the purification and characterization of an anti-bothropic factor from Didelphis marsupialis (opossum) serum.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(1):25-8.
1986: Jonas Perales; R Muñoz; H Moussatché
Isolation and partial characterization of a protein fraction from the opossum (Didelphis marsupialis) serum, with protecting property against the Bothrops jararaca snake venom.
Anais da Academia Brasileira de Ciências 1986;58(1):155-62.