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Matt Kaeberlein

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Saccharomyces cerevisiae

Chemicals & Drugs

Physiology

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Bo Xian; Tao Yu; Weiyang Chen; Zhijun Han; Yanyi Huang; Dongqing Jiang; Matt Kaeberlein; Yongfan Men; Yuhong Pang; Nan Qiao; Jie Shen; Na Sun; Jing-Dong J Han
WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis.
Elizabeth X Kwan; Mosur K Raghuraman; Scott Tsuchiyama; Gina M Alvino; Bonita J Brewer; Eric Foss; Matt Kaeberlein; Brian K Kennedy; Leonid Kruglyak; Antonio Bedalov
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.
Joe R Delaney; Marissa Fletcher; Sean Higgins; Monika Jelic; Umema Ahmed; Elroy H An; Daniel Carr; Anthony Castanza; Annie Chou; Brian Kennedy; Shannon Klum; Brian Muller; Christopher J Murakami; Zhao J Peng; Dilreet Rai; Vanessa Ros; Jennifer Schleit; Sylvia Sim; Minnie Singh; George L Sutphin; Helen V Wende; Matt Kaeberlein
Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.

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All Publications

2013: Bo Xian; Tao Yu; Weiyang Chen; Zhijun Han; Yanyi Huang; Dongqing Jiang; Matt Kaeberlein; Yongfan Men; Yuhong Pang; Nan Qiao; Jie Shen; Na Sun; Jing-Dong J Han
WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis.
Aging cell 2013;12(3):398-409.
2013: Elizabeth X Kwan; Mosur K Raghuraman; Scott Tsuchiyama; Gina M Alvino; Bonita J Brewer; Eric Foss; Matt Kaeberlein; Brian K Kennedy; Leonid Kruglyak; Antonio Bedalov
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.
PLoS genetics 2013;9(3):e1003329.
2013: Joe R Delaney; Marissa Fletcher; Sean Higgins; Monika Jelic; Umema Ahmed; Elroy H An; Daniel Carr; Anthony Castanza; Annie Chou; Brian Kennedy; Shannon Klum; Brian Muller; Christopher J Murakami; Zhao J Peng; Dilreet Rai; Vanessa Ros; Jennifer Schleit; Sylvia Sim; Minnie Singh; George L Sutphin; Helen V Wende; Matt Kaeberlein
Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.
Aging cell 2013;12(1):156-66.
2013: Simon C Johnson; Peter S Rabinovitch; Matt Kaeberlein
mTOR is a key modulator of ageing and age-related disease.
Nature 2013;493(7432):338-45.
2013: Matt Kaeberlein
Longevity and aging.
F1000prime reports 2013;5():5.
2013: Fresnida J Ramos; Matt Kaeberlein; Brian Kennedy
Elevated MTORC1 signaling and impaired autophagy.
Autophagy 2013;9(1):108-9.
2012: Baohua Liu; Xinguang Liu; Yousin Suh; Karl Tryggvason; Zimei Wang; Xi Yang; Bojian Zheng; Huiling Zheng; Shrestha Ghosh; Guoxiang Jin; Matt Kaeberlein; Brian K Kennedy; Zhongjun Zhou
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria.
Cell metabolism 2012;16(6):738-50.
2012: Melana E Yanos; Christopher F Bennett; Matt Kaeberlein
Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans.
Current genomics 2012;13(7):508-18.
2012: Matt Kaeberlein
Genomics and genetics of aging.
Current genomics 2012;13(7):499.
2012: Jennifer Schleit; Brian M Wasko; Matt Kaeberlein
Yeast as a model to understand the interaction between genotype and the response to calorie restriction.
FEBS letters 2012;586(18):2868-73.
2012: Fresnida J Ramos; Katherine H Schreiber; Randy Strong; Elroy H An; Steven C Chen; Dao-Fu Dai; Michael G Garelick; Matt Kaeberlein; Warren C Ladiges; Chen-Yu Liao; Vivian L MacKay; Peter S Rabinovitch; Brian Kennedy
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Science translational medicine 2012;4(144):144ra103.
2012: Valter D Longo; Gerald S Shadel; Matt Kaeberlein; Brian Kennedy
Replicative and chronological aging in Saccharomyces cerevisiae.
Cell metabolism 2012;16(1):18-31.
2012: Fresnida J Ramos; Matt Kaeberlein
Ageing: A healthy diet for stem cells.
Nature 2012;486(7404):477-8.
2012: Bing Zhou; Li Zhu; Haiyang Chen; Christopher D Green; Lei Hou; Jialiang Huang; Xun Huang; Matt Kaeberlein; Shoufeng Li; Yong Liu; Jinbo Wang; Huasheng Xiao; Zhen Yan; Liu Yang; Jing-Dong J Han
Midlife gene expressions identify modulators of aging through dietary interventions.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(19):E1201-9.
2012: Matt Kaeberlein
Hypertrophy and senescence factors in yeast aging. A reply to Bilinski et al.
FEMS yeast research 2012;12(3):269-70.
2012: Kristan K Steffen; Joe R Delaney; Matt Kaeberlein; Vivian L MacKay; Mark A McCormick; Christopher J Murakami; Kim M Pham; Brian Kennedy
Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae.
Genetics 2012;191(1):107-18.
2012: Matt Kaeberlein; Brian K Kennedy
A new chronological survival assay in mammalian cell culture.
Cell cycle (Georgetown, Tex.) 2012;11(2):201-2.
2012: George L Sutphin; Brian K Kennedy; Brady A Olsen; Matt Kaeberlein
Genome-wide analysis of yeast aging.
Sub-cellular biochemistry 2012;57():251-89.
2011: Camilla Burnett; Filipe Cabreiro; Daniel Ackerman; Catherine Au; Antonio Bedalov; Martin Goss; Matthew Hoddinott; Ken Howard; Matt Kaeberlein; Vid Leko; Joshua J McElwee; Christian Neri; Anne-Marie Orfila; Linda Partridge; Matthew D Piper; Michèle Riesen; Milán Somogyvári; Csaba Soti; George L Sutphin; Sara Valentini; Rafael Vázquez-Manrique; Giovanna Vinti; David Gems
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Nature 2011;477(7365):482-5.
2011: Undine Kruegel; Christopher J Murakami; Brett Robison; Jennifer Schleit; George Sutphin; Krisztina Tar; Mitsuhiro Tsuchiya; Scott Tsuchiyama; Daniel Carr; Thomas Dange; Joe R Delaney; Gunnar Dittmar; Matt Kaeberlein; Günther Kahlert; Brian K Kennedy; Soumya Kotireddy; Marion Schmidt
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.
PLoS genetics 2011;7(9):e1002253.
2011: Matt Kaeberlein; Brian K Kennedy; Xinguang Liu; Yousin Suh; Zhongjun Zhou
Trinations aging symposium.
Mechanisms of ageing and development 2011;132(6-7):348-52.
2011: Christopher R Burtner; Christopher J Murakami; Brady Olsen; Brian Kennedy; Matt Kaeberlein
A genomic analysis of chronological longevity factors in budding yeast.
Cell cycle (Georgetown, Tex.) 2011;10(9):1385-96.
2011: Scott F Leiser; Anisoara Begun; Matt Kaeberlein
HIF-1 modulates longevity and healthspan in a temperature-dependent manner.
Aging cell 2011;10(2):318-26.
2011: Matt Kaeberlein; Brian Kennedy
Hot topics in aging research: protein translation and TOR signaling, 2010.
Aging cell 2011;10(2):185-90.
2011: Hae Ri Choi; Kyung A Cho; hyun tae kang; Jung Bin Lee; Matt Kaeberlein; Yousin Suh; In Kwon Chung; Sang Chul Park
Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix.
Aging cell 2011;10(1):148-57.
2011: Jennifer Schleit; Marissa Simko; Valerie Z Wall; Matt Kaeberlein
The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans.
PloS one 2011;6(11):e28036.
2011: Christopher J Murakami; Valerie Wall; Nathan Basisty; Matt Kaeberlein
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast.
PloS one 2011;6(9):e24530.
2011: Joe R Delaney; Christopher J Murakami; Brady Olsen; Brian Kennedy; Matt Kaeberlein
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast.
Cell cycle (Georgetown, Tex.) 2011;10(1):156-65.
2010: Scott F Leiser; Matt Kaeberlein
The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging.
Biological chemistry 2010;391(10):1131-7.
2010: Scott F Leiser; Matt Kaeberlein
A role for SIRT1 in the hypoxic response.
Molecular cell 2010;38(6):779-80.
2010: Matt Kaeberlein
Lessons on longevity from budding yeast.
Nature 2010;464(7288):513-9.
2010: Matt Kaeberlein
Resveratrol and rapamycin: are they anti-aging drugs?
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(2):96-9.
2010: Ranjana Mehta; Devon Chandler-Brown; Fresnida J Ramos; Lara S Shamieh; Matt Kaeberlein
Regulation of mRNA translation as a conserved mechanism of longevity control.
Advances in experimental medicine and biology 2010;694():14-29.
2010: Brady Olsen; Christopher J Murakami; Matt Kaeberlein
YODA: software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast.
BMC bioinformatics 2010;11():141.
2009: Brian Kennedy; Matt Kaeberlein
Hot topics in aging research: protein translation, 2009.
Aging cell 2009;8(6):617-23.
2009: Matt Kaeberlein
Spermidine surprise for a long life.
Nature cell biology 2009;11(11):1277-8.
2009: Matt Kaeberlein; pankaj kapahi
Cell signaling. Aging is RSKy business.
Science (New York, N.Y.) 2009;326(5949):55-6.
2009: Monique N Stanfel; Lara S Shamieh; Matt Kaeberlein; Brian Kennedy
The TOR pathway comes of age.
Biochimica et biophysica acta 2009;1790(10):1067-74.
2009: Matt Kaeberlein; pankaj kapahi
The hypoxic response and aging.
Cell cycle (Georgetown, Tex.) 2009;8(15):2324.
2009: Matt Kaeberlein; Brian K Kennedy
Ageing: A midlife longevity drug?
Nature 2009;460(7253):331-2.
2009: Weiwei Dang; Kristan K Steffen; Rocco Perry; Jean A Dorsey; F Brad Johnson; Ali Shilatifard; Matt Kaeberlein; Brian K Kennedy; Shelley L Berger
Histone H4 lysine 16 acetylation regulates cellular lifespan.
Nature 2009;459(7248):802-7.
2009: Ranjana Mehta; Katherine A Steinkraus; George L Sutphin; Fresnida J Ramos; Lara S Shamieh; Alexander Huh; Christina Davis; Devon Chandler-Brown; Matt Kaeberlein
Proteasomal regulation of the hypoxic response modulates aging in C. elegans.
Science (New York, N.Y.) 2009;324(5931):1196-8.
2009: Christopher R Burtner; Christopher J Murakami; Brian Kennedy; Matt Kaeberlein
A molecular mechanism of chronological aging in yeast.
Cell cycle (Georgetown, Tex.) 2009;8(8):1256-70.
2009: Kristan K Steffen; Brian Kennedy; Matt Kaeberlein
Measuring replicative life span in the budding yeast.
Journal of visualized experiments : JoVE 2009;(28):.
2009: Christopher R Burtner; Christopher J Murakami; Matt Kaeberlein
A genomic approach to yeast chronological aging.
Methods in molecular biology (Clifton, N.J.) 2009;548():101-14.
2009: George L Sutphin; Matt Kaeberlein
Measuring Caenorhabditis elegans life span on solid media.
Journal of visualized experiments : JoVE 2009;(27):.
2009: Christopher Murakami; Matt Kaeberlein
Quantifying yeast chronological life span by outgrowth of aged cells.
Journal of visualized experiments : JoVE 2009;(27):.
2008: Matt Kaeberlein; Brian Kennedy
Protein translation, 2008.
Aging cell 2008;7(6):777-82.
2008: Matt Kaeberlein
Cell biology: A molecular age barrier.
Nature 2008;454(7205):709-10.
2008: Matt Kaeberlein
The ongoing saga of sirtuins and aging.
Cell metabolism 2008;8(1):4-5.
2008: Katherine A Steinkraus; Erica D Smith; Christina Davis; Daniel Carr; William R Pendergrass; George L Sutphin; Brian Kennedy; Matt Kaeberlein
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.
Aging cell 2008;7(3):394-404.
2008: Kristan K Steffen; Vivian L MacKay; Emily O Kerr; Mitsuhiro Tsuchiya; Di Hu; Lindsay A Fox; Nick Dang; Elijah D Johnston; Jonathan A Oakes; Bie N Tchao; Diana N Pak; Stanley Fields; Brian Kennedy; Matt Kaeberlein
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell 2008;133(2):292-302.
2008: Rita B Effros; Steven Austad; Helen Blau; Marie-Francoise Chesselet; Donald Ingram; Thomas Johnson; Matt Kaeberlein; Vicki Lundblad; Roger McCarter; Janet McElhaney; Michael Saag
The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(4):331-7.
2008: Erica D Smith; Mitsuhiro Tsuchiya; Lindsay A Fox; Nick Dang; Di Hu; Emily O Kerr; Elijah D Johnston; Bie N Tchao; Diana N Pak; K Linnea Welton; Daniel E L Promislow; James H Thomas; Matt Kaeberlein; Brian Kennedy
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome research 2008;18(4):564-70.
2008: George L Sutphin; Matt Kaeberlein
Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes.
Experimental gerontology 2008;43(3):130-5.
2008: Tom Schmidlin; Matt Kaeberlein; Brian A Kudlow; Vivian MacKay; Daniel Lockshon; Brian Kennedy
Single-gene deletions that restore mating competence to diploid yeast.
FEMS yeast research 2008;8(2):276-86.
2008: Christopher J Murakami; Christopher R Burtner; Brian Kennedy; Matt Kaeberlein
A method for high-throughput quantitative analysis of yeast chronological life span.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(2):113-21.
2008: J R Managbanag; Tarynn M Witten; Danail Bonchev; Lindsay A Fox; Mitsuhiro Tsuchiya; Brian K Kennedy; Matt Kaeberlein
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.
PloS one 2008;3(11):e3802.
2008: K A Steinkraus; Matt Kaeberlein; B K Kennedy
Replicative aging in yeast: the means to the end.
Annual review of cell and developmental biology 2008;24():29-54.
2008: Erica D Smith; Tammi L Kaeberlein; Brynn T Lydum; Jennifer Sager; K Linnea Welton; Brian Kennedy; Matt Kaeberlein
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.
BMC developmental biology 2008;8():49.
2007: Matt Kaeberlein; Brian Kennedy
Protein translation, 2007.
Aging cell 2007;6(6):731-4.
2007: Matt Kaeberlein
Molecular basis of ageing.
EMBO reports 2007;8(10):907-11.
2007: Matt Kaeberlein; Brian Kennedy
Does resveratrol activate yeast Sir2 in vivo?
Aging cell 2007;6(4):415-6.
2007: Matt Kaeberlein; R Wilson Powers
Sir2 and calorie restriction in yeast: a skeptical perspective.
Ageing research reviews 2007;6(2):128-40.
2007: Brian Kennedy; Kristan K Steffen; Matt Kaeberlein
Ruminations on dietary restriction and aging.
Cellular and molecular life sciences : CMLS 2007;64(11):1323-8.
2007: Matt Kaeberlein; Christopher R Burtner; Brian Kennedy
Recent developments in yeast aging.
PLoS genetics 2007;3(5):e84.
2007: Matt Kaeberlein
Longevity genomics across species.
Current genomics 2007;8(2):73-8.
2007: Daniel Lockshon; Lauren E Surface; Emily O Kerr; Matt Kaeberlein; Brian Kennedy
The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function.
Genetics 2007;175(1):77-91.
2007: Erica D Smith; Brian Kennedy; Matt Kaeberlein
Genome-wide identification of conserved longevity genes in yeast and worms.
Mechanisms of ageing and development 2007;128(1):106-11.
2006: Mitsuhiro Tsuchiya; Nick Dang; Emily O Kerr; Di Hu; Kristan K Steffen; Jonathan A Oakes; Brian Kennedy; Matt Kaeberlein
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
Aging cell 2006;5(6):505-14.
2006: Tammi L Kaeberlein; Erica D Smith; Mitsuhiro Tsuchiya; K Linnea Welton; James H Thomas; Stanley Fields; Brian Kennedy; Matt Kaeberlein
Lifespan extension in Caenorhabditis elegans by complete removal of food.
Aging cell 2006;5(6):487-94.
2006: Matt Kaeberlein; Peter S Rabinovitch
Medicine: grapes versus gluttony.
Nature 2006;444(7117):280-1.
2006: Matt Kaeberlein; Kristan K Steffen; Di Hu; Nick Dang; Emily O Kerr; Mitsuhiro Tsuchiya; Stanley Fields; Brian Kennedy
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".
Science (New York, N.Y.) 2006;312(5778):1312; author reply 1312.
2006: Matt Kaeberlein
Genome-wide approaches to understanding human ageing.
Human genomics 2006;2(6):422-8.
2006: R Wilson Powers; Matt Kaeberlein; Seth D Caldwell; Brian Kennedy; Stanley Fields
Extension of chronological life span in yeast by decreased TOR pathway signaling.
Genes & development 2006;20(2):174-84.
2005: Matt Kaeberlein; R Wilson Powers; Kristan K Steffen; Eric A Westman; Di Hu; Nick Dang; Emily O Kerr; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science (New York, N.Y.) 2005;310(5751):1193-6.
2005: Brian Kennedy; Erica D Smith; Matt Kaeberlein
The enigmatic role of Sir2 in aging.
Cell 2005;123(4):548-50.
2005: Matt Kaeberlein; Di Hu; Emily O Kerr; Mitsuhiro Tsuchiya; Eric A Westman; Nick Dang; Stanley Fields; Brian Kennedy
Increased life span due to calorie restriction in respiratory-deficient yeast.
PLoS genetics 2005;1(5):e69.
2005: Matt Kaeberlein; Thomas McDonagh; Birgit Heltweg; Jeffrey Hixon; Eric A Westman; Seth D Caldwell; Andrew D Napper; Rory Curtis; Peter S DiStefano; Stanley Fields; Antonio Bedalov; Brian Kennedy
Substrate-specific activation of sirtuins by resveratrol.
The Journal of biological chemistry 2005;280(17):17038-45.
2005: Matt Kaeberlein; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Genes determining yeast replicative life span in a long-lived genetic background.
Mechanisms of ageing and development 2005;126(4):491-504.
2005: Matt Kaeberlein; Brian Kennedy
Large-scale identification in yeast of conserved ageing genes.
Mechanisms of ageing and development 2005;126(1):17-21.
2004: Matt Kaeberlein
Aging-related research in the "-omics" age.
Science of aging knowledge environment : SAGE KE 2004;2004(42):pe39.
2004: Matt Kaeberlein; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Sir2-independent life span extension by calorie restriction in yeast.
PLoS biology 2004;2(9):E296.
2004: Matt Kaeberlein; Alex A Andalis; Gregory Liszt; Gerald R Fink; Leonard Guarente
Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism.
Genetics 2004;166(4):1661-72.
2002: Matt Kaeberlein; Alex A Andalis; Gerald R Fink; Leonard Guarente
High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.
Molecular and cellular biology 2002;22(22):8056-66.
2002: Su-Ju Lin; Matt Kaeberlein; Alex A Andalis; Lori A Sturtz; Pierre-Antoine Defossez; Valeria Cizewski Culotta; Gerald R Fink; Leonard Guarente
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.
Nature 2002;418(6895):344-8.
2002: Matt Kaeberlein; Beatrice Jegalian; Mitch McVey
AGEID: a database of aging genes and interventions.
Mechanisms of ageing and development 2002;123(8):1115-9.
2002: Christopher M Armstrong; Matt Kaeberlein; Shinichiro Imai; Leonard Guarente
Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity.
Molecular biology of the cell 2002;13(4):1427-38.
2002: Matt Kaeberlein; Leonard Guarente
Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity.
Genetics 2002;160(1):83-95.
2001: Matt Kaeberlein; Mitch McVey; Leonard Guarente
Using yeast to discover the fountain of youth.
Science of aging knowledge environment : SAGE KE 2001;2001(1):pe1.
2001: Mitch McVey; Matt Kaeberlein; Heidi A Tissenbaum; Leonard Guarente
The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination.
Genetics 2001;157(4):1531-42.
2000: Mary Anne Pultz; K K Zimmerman; N M Alto; Matt Kaeberlein; S K Lange; Jason N Pitt; Nick L Reeves; D L Zehrung
A genetic screen for zygotic embryonic lethal mutations affecting cuticular morphology in the wasp Nasonia vitripennis.
Genetics 2000;154(3):1213-29.
2000: Shinichiro Imai; C M Armstrong; Matt Kaeberlein; Leonard Guarente
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.
Nature 2000;403(6771):795-800.
1999: Matt Kaeberlein; Mitch McVey; Leonard Guarente
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.
Genes & development 1999;13(19):2570-80.
1999: Pierre-Antoine Defossez; R Prusty; Matt Kaeberlein; Su-Ju Lin; P Ferrigno; P A Silver; Ralph L Keil; Leonard Guarente
Elimination of replication block protein Fob1 extends the life span of yeast mother cells.
Molecular cell 1999;3(4):447-55.