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Kevin Wang
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50
Hayes, Ronald
16
Pike, Brian
14
Kobeissy, Firas
12
Ottens, Andrew
11
Roufogalis, Basil
11
Gnegy, Margaret
11
Liu, Ming Cheng
11
McGinnis, Kim
8
Larner, Stephen
8
Zhao, Xiurong
7
Pineda, Jose
7
Newcomb, JK
6
Gold, Mark
6
Denslow, Nancy
6
Posmantur, RM
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All Publications
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2008: Kobeissy Firas H; Warren Matthew W; Ottens Andrew K; Sadasivan Shankar; Zhang Zhiqun; Gold Mark S; Wang Kevin K W
Psychoproteomic analysis of rat cortex following acute methamphetamine exposure.
Journal of proteome research 2008;7(5):1971-83.
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2008: Kobeissy Firas H; Sadasivan Shankar; Liu Jing; Gold Mark S; Wang Kevin K W
Psychiatric research: psychoproteomics, degradomics and systems biology.
Expert review of proteomics 2008;5(2):293-314.
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2008: Ottens Andrew K; Golden Erin C; Bustamante Liliana; Hayes Ronald L; Denslow Nancy D; Wang Kevin K W
Proteolysis of multiple myelin basic protein isoforms after neurotrauma: characterization by mass spectrometry.
Journal of neurochemistry 2008;104(5):1404-14.
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2008: Liu Jing; Liu Ming Cheng; Wang Kevin K W
Physiological and pathological actions of calpains in glutamatergic neurons.
Science signaling 2008;1(23):tr3.
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2008: Liu Jing; Liu Ming Cheng; Wang Kevin K W
Calpain in the CNS: from synaptic function to neurotoxicity.
Science signaling 2008;1(14):re1.
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2007: Lewis Stephen B; Velat Gregory J; Miralia Lynn; Papa Linda; Aikman Jada M; Wolper Regina A; Firment Chris S; Liu Ming Chen; Pineda Jose A; Wang Kevin K W; Hayes Ronald L
Alpha-II spectrin breakdown products in aneurysmal subarachnoid hemorrhage: a novel biomarker of proteolytic injury.
Journal of neurosurgery 2007;107(4):792-6.
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2007: Warren Matthew W; Larner Stephen F; Kobeissy Firas H; Brezing Christina A; Jeung Jennifer A; Hayes Ronald L; Gold Mark S; Wang Kevin K W
Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA.
Acta neuropathologica 2007;114(3):277-86.
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2007: Warren Matthew W; Zheng Wenrong; Kobeissy Firas H; Cheng Liu Ming; Hayes Ronald L; Gold Mark S; Larner Stephen F; Wang Kevin K W
Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2007;10(4):479-89.
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2007: Germanò Antonino; Caffo Mariella; Angileri Filippo Flavio; Arcadi Francesca; Newcomb-Fernandez Jennifer; Caruso Gerardo; Meli Francesco; Pineda Jose A; Lewis Stephen B; Wang Kevin K W; Bramanti Placido; Costa Chiara; Hayes Ronald L
NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat.
Journal of neurotrauma 2007;24(4):732-44.
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2007: Zhang Zhiqun; Ottens Andrew K; Sadasivan Shankar; Kobeissy Firas H; Fang Tie; Hayes Ronald L; Wang Kevin K W
Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury.
Journal of neurotrauma 2007;24(3):460-72.
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2007: Pineda Jose A; Lewis Stephen B; Valadka Alex B; Papa Linda; Hannay H Julia; Heaton Shelley C; Demery Jason A; Liu Ming Cheng; Aikman Jada M; Akle Veronica; Brophy Gretchen M; Tepas Joseph J; Wang Kevin K W; Robertson Claudia S; Hayes Ronald L
Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury.
Journal of neurotrauma 2007;24(2):354-66.
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2007: Glantz Susan B; Cianci Carol D; Iyer Rathna; Pradhan Deepti; Wang Kevin K W; Morrow Jon S
Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells.
Biochemistry 2007;46(2):502-13.
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2007: Ottens Andrew K; Kobeissy Firas H; Fuller Brian F; Liu Ming Chen; Oli Monika W; Hayes Ronald L; Wang Kevin K W
Novel neuroproteomic approaches to studying traumatic brain injury.
Progress in brain research 2007;161():401-18.
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2006: Wang Kevin K W; Larner Stephen F; Robinson Gillian; Hayes Ronald L
Neuroprotection targets after traumatic brain injury.
Current opinion in neurology 2006;19(6):514-9.
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2006: Xiang Yiwen; Johnson Erik A; Zhang Chun; Huang Guangling; Hayes Ronald L; Wang Kevin K W; Svetlov Stanislav I
Generation of aberrant forms of DFF40 concurrent with caspase-3 activation during acute and chronic liver injury in rats.
Biochemical and biophysical research communications 2006;350(2):457-62.
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2006: Kobeissy Firas H; Ottens Andrew K; Zhang Zhiqun; Liu Ming Cheng; Denslow Nancy D; Dave Jitendra R; Tortella Frank C; Hayes Ronald L; Wang Kevin K W
Novel differential neuroproteomics analysis of traumatic brain injury in rats.
Molecular & cellular proteomics : MCP 2006;5(10):1887-98.
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2006: Sadasivan Shankar; Waghray Anu; Larner Stephen F; Dunn William A; Hayes Ronald L; Wang Kevin K W
Amino acid starvation induced autophagic cell death in PC-12 cells: evidence for activation of caspase-3 but not calpain-1.
Apoptosis : an international journal on programmed cell death 2006;11(9):1573-82.
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2006: Liu Ming Cheng; Akle Veronica; Zheng Wenrong; Kitlen Jason; O'Steen Barbara; Larner Stephen F; Dave Jitendra R; Tortella Frank C; Hayes Ronald L; Wang Kevin K W
Extensive degradation of myelin basic protein isoforms by calpain following traumatic brain injury.
Journal of neurochemistry 2006;98(3):700-12.
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2006: Svetlov S I; Xiang Y; Oli M W; Foley D P; Huang G; Hayes R L; Ottens A K; Wang K K W
Identification and preliminary validation of novel biomarkers of acute hepatic ischaemia/reperfusion injury using dual-platform proteomic/degradomic approaches.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2006;11(4):355-69.
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2006: Larner Stephen F; Hayes Ronald L; Wang Kevin K W
Unfolded protein response after neurotrauma.
Journal of neurotrauma 2006;23(6):807-29.
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2006: Ottens Andrew K; Kobeissy Firas H; Golden Erin C; Zhang Zhiqun; Haskins William E; Chen Su-Shing; Hayes Ronald L; Wang Kevin K W; Denslow Nancy D
Neuroproteomics in neurotrauma.
Mass spectrometry reviews 2006;25(3):380-408.
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2006: Bernath Eric; Kupina Nancy; Liu Ming Cheng; Hayes Ronald L; Meegan Colleen; Wang Kevin K W
Elevation of cytoskeletal protein breakdown in aged Wistar rat brain.
Neurobiology of aging 2006;27(4):624-32.
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2006: Liu Ming Cheng; Akle Veronica; Zheng Wenrong; Dave Jitendra R; Tortella Frank C; Hayes Ronald L; Wang Kevin K W
Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis.
The Biochemical journal 2006;394(Pt 3):715-25.
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2006: French Joel P; Quindry John C; Falk Darin J; Staib Jessica L; Lee Youngil; Wang Kevin K W; Powers Scott K
Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H128-36.
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2006: Warren Matthew W; Kobeissy Firas H; Liu Ming Cheng; Hayes Ronald L; Gold Mark S; Wang Kevin K W
Ecstasy toxicity: a comparison to methamphetamine and traumatic brain injury.
Journal of addictive diseases 2006;25(4):115-23.
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2006: Aikman J; O'Steen B; Silver X; Torres R; Boslaugh S; Blackband S; Padgett K; Wang K K W; Hayes R; Pineda J
Alpha-II-spectrin after controlled cortical impact in the immature rat brain.
Developmental neuroscience 2006;28(4-5):457-65.
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2006: Zhang Zhiqun; Ottens Andrew K; Larner Stephen F; Kobeissy Firas H; Williams Melissa L; Hayes Ronald L; Wang Kevin K W
Direct Rho-associated kinase inhibition [correction of inhibiton] induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells.
Cellular & molecular biology letters 2006;11(1):12-29.
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2005: Warren Matthew W; Kobeissy Firas H; Liu Ming Cheng; Hayes Ronald L; Gold Mark S; Wang Kevin K W
Concurrent calpain and caspase-3 mediated proteolysis of alpha II-spectrin and tau in rat brain after methamphetamine exposure: a similar profile to traumatic brain injury.
Life sciences 2005;78(3):301-9.
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2005: Johnson Erik A; Svetlov Stanislav I; Wang Kevin K W; Hayes Ronald L; Pineda Jose A
Cell-specific DNA fragmentation may be attenuated by a survivin-dependent mechanism after traumatic brain injury in rats.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;167(1):17-26.
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2005: Wang Kevin K W; Ottens Andrew K; Liu Ming Cheng; Lewis Stephen B; Meegan Colleen; Oli Monika W; Tortella Frank C; Hayes Ronald L
Proteomic identification of biomarkers of traumatic brain injury.
Expert review of proteomics 2005;2(4):603-14.
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2005: Ottens Andrew K; Kobeissy Firas H; Wolper Regina A; Haskins William E; Hayes Ronald L; Denslow Nancy D; Wang Kevin K W
A multidimensional differential proteomic platform using dual-phase ion-exchange chromatography-polyacrylamide gel electrophoresis/reversed-phase liquid chromatography tandem mass spectrometry.
Analytical chemistry 2005;77(15):4836-45.
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2005: Haskins William E; Kobeissy Firas H; Wolper Regina A; Ottens Andrew K; Kitlen Jason W; McClung Scott H; O'Steen Barbara E; Chow Marjorie M; Pineda Jose A; Denslow Nancy D; Hayes Ronald L; Wang Kevin K W
Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry.
Journal of neurotrauma 2005;22(6):629-44.
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2005: Ellis Rebecca C; O'Steen Wilbur A; Hayes Ronald L; Nick Harry S; Wang Kevin K W; Anderson Douglas K
Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat.
Experimental neurology 2005;193(1):19-28.
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2004: Svetlov Stanislav I; Ignatova Tatyana N; Wang Kevin K W; Hayes Ronald L; English Denis; Kukekov Valery G
Lysophosphatidic acid induces clonal generation of mouse neurospheres via proliferation of Sca-1- and AC133-positive neural progenitors.
Stem cells and development 2004;13(6):685-93.
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2004: Waghray Anuradhaa; Wang Deng-shun; McKinsey Deborah; Hayes Ronald L; Wang Kevin K W
Molecular cloning and characterization of rat and human calpain-5.
Biochemical and biophysical research communications 2004;324(1):46-51.
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2004: Ringger N C; O'Steen B E; Brabham J G; Silver X; Pineda J; Wang K K W; Hayes R L; Papa L
A novel marker for traumatic brain injury: CSF alphaII-spectrin breakdown product levels.
Journal of neurotrauma 2004;21(10):1443-56.
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2004: Johnson Erik A; Svetlov Stanislav I; Pike Brian R; Tolentino Paul J; Shaw Gerald; Wang Kevin K W; Hayes Ronald L; Pineda Jose A
Cell-specific upregulation of survivin after experimental traumatic brain injury in rats.
Journal of neurotrauma 2004;21(9):1183-95.
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2004: Ringger N C; Tolentino P J; McKinsey D M; Pike B R; Wang K K W; Hayes R L
Effects of injury severity on regional and temporal mRNA expression levels of calpains and caspases after traumatic brain injury in rats.
Journal of neurotrauma 2004;21(7):829-41.
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2004: Tolentino Paul J; Waghray Anuradha; Wang Kevin K W; Hayes Ronald L
Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats.
Journal of neurochemistry 2004;89(5):1301-7.
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2004: Pineda Jose A; Wang Kevin K; Hayes Ronald L
Biomarkers of proteolytic damage following traumatic brain injury.
Brain pathology (Zurich, Switzerland) 2004;14(2):202-9.
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2004: Ellis Rebecca C; Earnhardt J Nicole; Hayes Ronald L; Wang Kevin K W; Anderson Douglas K
Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats.
Journal of neurochemistry 2004;88(3):689-97.
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2004: Pike Brian R; Flint Jeremy; Dave Jitendra R; Lu X-C May; Wang Kevin K K; Tortella Frank C; Hayes Ronald L
Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(1):98-106.
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2004: Larner Stephen F; Hayes Ronald L; McKinsey Deborah M; Pike Brian R; Wang Kevin K W
Increased expression and processing of caspase-12 after traumatic brain injury in rats.
Journal of neurochemistry 2004;88(1):78-90.
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2004: Wang Kevin K W; Ottens Andrew; Haskins William; Liu Ming Cheng; Kobeissy Firas; Denslow Nancy; Chen Sushing; Hayes Ronald L
Proteomics studies of traumatic brain injury.
International review of neurobiology 2004;61():215-40.
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2003: Park Yang Hae; Kantor Lana; Guptaroy Bipasha; Zhang Minjia; Wang Kevin K W; Gnegy Margaret E
Repeated amphetamine treatment induces neurite outgrowth and enhanced amphetamine-stimulated dopamine release in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism.
Journal of neurochemistry 2003;87(6):1546-57.
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2003: McGinnis Kim M; Gnegy Margaret E; Falk Nicole; Nath Rathna; Wang Kevin K W
Cytochrome c translocation does not lead to caspase activation in maitotoxin-treated SH-SY5Y neuroblastoma cells.
Neurochemistry international 2003;42(6):517-23.
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2003: Todd Bice; Moore Dwight; Deivanayagam Champion C S; Lin Guang-da; Chattopadhyay Debasish; Maki Masatoshi; Wang Kevin K W; Narayana Sthanam V L
A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
Journal of molecular biology 2003;328(1):131-46.
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2003: Inoue Jun; Nakamura Masayuki; Cui Ying-She; Sakai Yusuke; Sakai Osamu; Hill Jeanette R; Wang Kevin K W; Yuen Po-Wai
Structure-activity relationship study and drug profile of N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal (SJA6017) as a potent calpain inhibitor.
Journal of medicinal chemistry 2003;46(5):868-71.
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2002: Park Yang Hae; Kantor Lana; Wang Kevin K W; Gnegy Margaret E
Repeated, intermittent treatment with amphetamine induces neurite outgrowth in rat pheochromocytoma cells (PC12 cells).
Brain research 2002;951(1):43-52.
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2002: Kantor Lana; Park Yang Hae; Wang Kevin K W; Gnegy Margaret
Enhanced amphetamine-mediated dopamine release develops in PC12 cells after repeated amphetamine treatment.
European journal of pharmacology 2002;451(1):27-35.
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2002: Franz Gerhard; Beer Ronny; Intemann Denis; Krajewski Stanislaw; Reed John C; Engelhardt Klaus; Pike Brian R; Hayes Ronald L; Wang Kevin K; Schmutzhard Erich; Kampfl Andreas
Temporal and spatial profile of Bid cleavage after experimental traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(8):951-8.
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2002: Wang Kevin K W
Assaying proteases in cellular environments.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2002;Chapter 21():Unit 21.12.
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2002: Dutta Satavisha; Chiu Yuk Chun; Probert Albert W; Wang Kevin K W
Selective release of calpain produced alphalI-spectrin (alpha-fodrin) breakdown products by acute neuronal cell death.
Biological chemistry 2002;383(5):785-91.
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2002: Huang Yuanhui; Tan Mingjia; Gosink Mark; Wang Kevin K W; Sun Yi
Histone deacetylase 5 is not a p53 target gene, but its overexpression inhibits tumor cell growth and induces apoptosis.
Cancer research 2002;62(10):2913-22.
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2002: Bian Feng; Nath Rathna; Sobocinski Gregg; Booher Robert N; Lipinski William J; Callahan Michael J; Pack Amy; Wang Kevin K-W; Walker Lary C
Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice.
The Journal of comparative neurology 2002;446(3):257-66.
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2002: Tolentino Paul J; DeFord S Michelle; Notterpek Lucia; Glenn Christopher C; Pike Brian R; Wang Kevin K W; Hayes Ronald L
Up-regulation of tissue-type transglutaminase after traumatic brain injury.
Journal of neurochemistry 2002;80(4):579-88.
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2001: Kupina N C; Nath R; Bernath E E; Inoue J; Mitsuyoshi A; Yuen P W; Wang K K; Hall E D
The novel calpain inhibitor SJA6017 improves functional outcome after delayed administration in a mouse model of diffuse brain injury.
Journal of neurotrauma 2001;18(11):1229-40.
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2001: Newcomb-Fernandez J K; Zhao X; Pike B R; Wang K K; Kampfl A; Beer R; DeFord S M; Hayes R L
Concurrent assessment of calpain and caspase-3 activation after oxygen-glucose deprivation in primary septo-hippocampal cultures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(11):1281-94.
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2001: Pike B R; Flint J; Dutta S; Johnson E; Wang K K; Hayes R L
Accumulation of non-erythroid alpha II-spectrin and calpain-cleaved alpha II-spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats.
Journal of neurochemistry 2001;78(6):1297-306.
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2001: Beer R; Franz G; Krajewski S; Pike B R; Hayes R L; Reed J C; Wang K K; Klimmer C; Schmutzhard E; Poewe W; Kampfl A
Temporal and spatial profile of caspase 8 expression and proteolysis after experimental traumatic brain injury.
Journal of neurochemistry 2001;78(4):862-73.
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2001: Mukerjee N; McGinnis K M; Gnegy M E; Wang K K
Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.
Biochemical and biophysical research communications 2001;285(5):1192-9.
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2001: Huang Y; Shin N H; Sun Y; Wang K K
Molecular cloning and characterization of a novel caspase-3 variant that attenuates apoptosis induced by proteasome inhibition.
Biochemical and biophysical research communications 2001;283(4):762-9.
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2001: Zhao X; Bausano B; Pike B R; Newcomb-Fernandez J K; Wang K K; Shohami E; Ringger N C; DeFord S M; Anderson D K; Hayes R L
TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.
Journal of neuroscience research 2001;64(2):121-31.
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2001: McGinnis K M; Wang K K; Gnegy M E
Calcium/calmodulin-dependent protein kinase inhibition potentiates thapsigargin-mediated cell death in SH-SY5Y human neuroblastoma cells.
Neuroscience letters 2001;301(2):99-102.
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2001: Nath R; McGinnis K; Dutta S; Shivers B; Wang K K
Inhibition of p38 kinase mimics survival signal-linked protection against apoptosis in rat cerebellar granule neurons.
Cellular & molecular biology letters 2001;6(2):173-84.
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2000: Mukerjee N; McGinnis K M; Park Y H; Gnegy M E; Wang K K
Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells.
Archives of biochemistry and biophysics 2000;379(2):337-43.
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2000: Zhao X; Newcomb J K; Pike B R; Wang K K; d'Avella D; Hayes R L
Novel characteristics of glutamate-induced cell death in primary septohippocampal cultures: relationship to calpain and caspase-3 protease activation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):550-62.
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1999: McGinnis K M; Gnegy M E; Park Y H; Mukerjee N; Wang K K
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.
Biochemical and biophysical research communications 1999;263(1):94-9.
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1999: McGinnis K M; Gnegy M E; Wang K K
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis.
Journal of neurochemistry 1999;72(5):1899-906.
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1999: McGinnis K M; Wang K K; Gnegy M E
Alterations of extracellular calcium elicit selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 1999;72(5):1853-63.
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1999: Zhao X; Pike B R; Newcomb J K; Wang K K; Posmantur R M; Hayes R L
Maitotoxin induces calpain but not caspase-3 activation and necrotic cell death in primary septo-hippocampal cultures.
Neurochemical research 1999;24(3):371-82.
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1998: Posmantur R; Wang K K; Gilbertsen R B
Caspase-3-like activity is necessary for IL-2 release in activated Jurkat T-cells.
Experimental cell research 1998;244(1):302-9.
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1998: Pike B R; Zhao X; Newcomb J K; Posmantur R M; Wang K K; Hayes R L
Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury.
Neuroreport 1998;9(11):2437-42.
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1998: Wang K K; Posmantur R; Nath R; McGinnis K; Whitton M; Talanian R V; Glantz S B; Morrow J S
Simultaneous degradation of alphaII- and betaII-spectrin by caspase 3 (CPP32) in apoptotic cells.
The Journal of biological chemistry 1998;273(35):22490-7.
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1998: Wang K K; Posmantur R; Nadimpalli R; Nath R; Mohan P; Nixon R A; Talanian R V; Keegan M; Herzog L; Allen H
Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis.
Archives of biochemistry and biophysics 1998;356(2):187-96.
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1998: McGinnis K M; Whitton M M; Gnegy M E; Wang K K
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
The Journal of biological chemistry 1998;273(32):19993-20000.
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1998: Pike B R; Zhao X; Newcomb J K; Wang K K; Posmantur R M; Hayes R L
Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures.
Journal of neuroscience research 1998;52(5):505-20.
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1998: Hayes R L; Wang K K; Kampfl A; Posmantur R M; Newcomb J K; Clifton G L
Potential contribution of proteases to neuronal damage.
Drug news & perspectives 1998;11(4):215-22.
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1998: Zhao X; Newcomb J K; Posmantur R M; Wang K K; Pike B R; Hayes R L
pH dependency of mu-calpain and m-calpain activity assayed by casein zymography following traumatic brain injury in the rat.
Neuroscience letters 1998;247(1):53-7.
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1998: Zhao X; Posmantur R; Kampfl A; Liu S J; Wang K K; Newcomb J K; Pike B R; Clifton G L; Hayes R L
Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: a casein zymography study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(2):161-7.
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1997: Posmantur R; Wang K K; Nath R; Gilbertsen R B
A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells.
Immunopharmacology 1997;37(2-3):231-44.
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1997: Gilbertsen R B; Posmantur R; Nath R; Wang K K
Apoptotic death induced in MOLT-4 T-lymphoblasts by purine nucleoside phosphorylase inhibition.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 2():S151-2.
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1997: Lin G D; Chattopadhyay D; Maki M; Wang K K; Carson M; Jin L; Yuen P W; Takano E; Hatanaka M; DeLucas L J; Narayana S V
Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
Nature structural biology 1997;4(7):539-47.
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1997: Posmantur R; McGinnis K; Nadimpalli R; Gilbertsen R B; Wang K K
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells.
Journal of neurochemistry 1997;68(6):2328-37.
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1997: Wang K K; Yuen P W
Development and therapeutic potential of calpain inhibitors.
Advances in pharmacology (San Diego, Calif.) 1997;37():117-52.
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1996: Nath R; Raser K J; McGinnis K; Nadimpalli R; Stafford D; Wang K K
Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis.
Neuroreport 1996;8(1):249-55.
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1996: Nath R; Raser K J; Stafford D; Hajimohammadreza I; Posner A; Allen H; Talanian R V; Yuen P; Gilbertsen R B; Wang K K
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis.
The Biochemical journal 1996;319 ( Pt 3)():683-90.
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1996: Wang K K; Nath R; Raser K J; Hajimohammadreza I
Maitotoxin induces calpain activation in SH-SY5Y neuroblastoma cells and cerebrocortical cultures.
Archives of biochemistry and biophysics 1996;331(2):208-14.
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1996: Wang K K; Nath R; Posner A; Raser K J; Buroker-Kilgore M; Hajimohammadreza I; Probert A W; Marcoux F W; Ye Q; Takano E; Hatanaka M; Maki M; Caner H; Collins J L; Fergus A; Lee K S; Lunney E A; Hays S J; Yuen P
An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6687-92.
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1996: Wang K K; Posner A; Raser K J; Buroker-Kilgore M; Nath R; Hajimohammadreza I; Probert A W; Marcoux F W; Lunney E A; Hays S J; Yuen P-W
Alpha-mercaptoacrylic acid derivatives as novel selective calpain inhibitors.
Advances in experimental medicine and biology 1996;389():95-101.
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1995: Posner A; Raser K J; Hajimohammadreza I; Yuen P W; Wang K K
Aurintricarboxylic acid is an inhibitor of mu- and m-calpain.
Biochemistry and molecular biology international 1995;36(2):291-9.
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1995: Hajimohammadreza I; Probert A W; Coughenour L L; Borosky S A; Marcoux F W; Boxer P A; Wang K K
A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 2):4093-101.
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1994: Wang K K; Yuen P W
Calpain inhibition: an overview of its therapeutic potential.
Trends in pharmacological sciences 1994;15(11):412-9.
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1994: Elvira M; Wang K K; Villalobo A
Phosphorylated and non-phosphorylated connexin-32 molecules in gap junction plaques are protected against calpain proteolysis after phosphorylation by protein kinase C.
Biochemical Society transactions 1994;22(3):793-6.
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1994: Khan M T; Wang K K; Villalobo A; Roufogalis B D
Characterization of a novel high molecular mass protein with peptidase activity purified from the human erythrocyte membrane by calmodulin affinity chromatography.
The Journal of biological chemistry 1994;269(13):10016-21.
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1993: Elvira M; Díez J A; Wang K K; Villalobo A
Phosphorylation of connexin-32 by protein kinase C prevents its proteolysis by mu-calpain and m-calpain.
The Journal of biological chemistry 1993;268(19):14294-300.
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1992: Kuo T H; Tsang W; Wang K K; Carlock L
Simultaneous reduction of the sarcolemmal and SR calcium ATPase activities and gene expression in cardiomyopathic hamster.
Biochimica et biophysica acta 1992;1138(4):343-9.
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1992: Wang K K; Villalobo A; Roufogalis B D
The plasma membrane calcium pump: a multiregulated transporter.
Trends in cell biology 1992;2(2):46-52.
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1991: Wang K K; Roufogalis B D; Kuo T H
Structure--function relationship of the human erythrocyte plasma membrane Ca(2+)-ATPase revealed by V8 protease treatment.
The Biochemical journal 1991;279 ( Pt 2)():537-44.
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1991: Wang K K; Du Y S; Diglio C; Tsang W; Kuo T H
Hormone-induced phosphorylation of the plasma membrane calcium pump in cultured aortic endothelial cells.
Archives of biochemistry and biophysics 1991;289(1):103-8.
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1991: Wang K K; Wright L C; Machan C L; Allen B G; Conigrave A D; Roufogalis B D
Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.
The Journal of biological chemistry 1991;266(14):9078-85.
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1991: Kuo T H; Wang K K; Carlock L; Diglio C; Tsang W
Phorbol ester induces both gene expression and phosphorylation of the plasma membrane Ca2+ pump.
The Journal of biological chemistry 1991;266(4):2520-5.
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1990: Roufogalis B D; Brzuszczak I; Conigrave A D; Xu Y H; Machan C L; Wang K K
Persistent Ca2(+)-induced activation of erythrocyte membrane Ca2(+)-ATPase unrelated to calpain proteolysis.
Archives of biochemistry and biophysics 1990;279(1):78-86.
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1990: Wang K K; Roufogalis B D; Villalobo A
Calpain I activates Ca2+ transport by the human erythrocyte plasma membrane calcium pump.
Advances in experimental medicine and biology 1990;269():175-80.
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1989: Wang K K; Roufogalis B D; Villalobo A
Calpain I activates Ca2+ transport by the reconstituted erythrocyte Ca2+ pump.
The Journal of membrane biology 1989;112(3):233-45.
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1989: Wang K K; Roufogalis B D; Villalobo A
Characterization of the fragmented forms of calcineurin produced by calpain I.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1989;67(10):703-11.
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1989: Wang K K; Villalobo A; Roufogalis B D
Calmodulin-binding proteins as calpain substrates.
The Biochemical journal 1989;262(3):693-706.
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1988: Olorunsogo O O; Villalobo A; Wang K K; Roufogalis B D
The effect of calmodulin on the interaction of carbodiimides with the purified human erythrocyte (Ca2+ + Mg2+)-ATPase.
Biochimica et biophysica acta 1988;945(1):33-40.
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1988: Wang K K; Roufogalis B D; Villalobo A
Further characterization of calpain-mediated proteolysis of the human erythrocyte plasma membrane Ca2+-ATPase.
Archives of biochemistry and biophysics 1988;267(1):317-27.
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1988: Wang K K; Villalobo A; Roufogalis B D
Activation of the Ca2+-ATPase of human erythrocyte membrane by an endogenous Ca2+-dependent neutral protease.
Archives of biochemistry and biophysics 1988;260(2):696-704.
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