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Anne Knowlton

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Le Chen; Nipavan Chiamvimonvat; Gino Cortopassi; Vanessa J Davies; Tingting Liu; Xiyuan Lu; Alexey A Tomilov; Alice Tran; Marcela Votruba; Donald M Bers; Anne Knowlton
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability.
Chongxiu Sun; Kayan Tam; Ying I Wang; Kenan Alkhoury; Ehrin J Armstrong; Christina M Edwards; Marc T Facciotti; Greg A Foster; Anne Knowlton; John William Newman; Anthony G Passerini; Christopher E Radecke; Scott I Simon
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal.
James P Stice; Fiona N Mbai; Le Chen; Anne Knowlton
Rapid activation of nuclear factor κB by 17β-estradiol and selective estrogen receptor modulators: pathways mediating cellular protection.

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All Publications

2012: Le Chen; Nipavan Chiamvimonvat; Gino Cortopassi; Vanessa J Davies; Tingting Liu; Xiyuan Lu; Alexey A Tomilov; Alice Tran; Marcela Votruba; Donald M Bers; Anne Knowlton
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability.
Journal of the American Heart Association 2012;1(5):e003012.
2012: Chongxiu Sun; Kayan Tam; Ying I Wang; Kenan Alkhoury; Ehrin J Armstrong; Christina M Edwards; Marc T Facciotti; Greg A Foster; Anne Knowlton; John William Newman; Anthony G Passerini; Christopher E Radecke; Scott I Simon
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal.
Circulation research 2012;111(8):1054-64.
2012: James P Stice; Fiona N Mbai; Le Chen; Anne Knowlton
Rapid activation of nuclear factor κB by 17β-estradiol and selective estrogen receptor modulators: pathways mediating cellular protection.
Shock (Augusta, Ga.) 2012;38(2):128-36.
2012: Anne Knowlton; A R Lee
Estrogen and the cardiovascular system.
Pharmacology & therapeutics 2012;135(1):54-70.
2012: Anne Knowlton; Le Chen
Regulating a uniter: control of mitofusin 2 expression.
Cardiovascular research 2012;94(1):6-7.
2012: Sanda Despa; Peter J Havel; Anne Knowlton; Kenneth B Margulies; Heinrich Taegtmeyer; Donald M Bers; Le Chen; Florin Despa
Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats.
Circulation research 2012;110(4):598-608.
2012: Claudio Blasi; Eunjung Kim; Anne Knowlton
Improved Metabolic Control in Diabetes, HSP60, and Proinflammatory Mediators.
Autoimmune diseases 2012;2012():346501.
2012: Anne Knowlton
Estrogen and cardiovascular disease: aging and estrogen loss at the heart of the matter?
Future cardiology 2012;8(1):9-12.
2012: Somak Das; Narasimman Gurusamy; Anne Knowlton; Istvan Lekli; Subhendu Mukherjee; Utpal Raychoudhury; Sandip Banerji; Jayeeta Bardhan; Runu Chakravarty; Dipak K Das
Tocotrienols confer resistance to ischemia in hypercholesterolemic hearts: insight with genomics.
Molecular and cellular biochemistry 2012;360(1-2):35-45.
2011: Le Chen; Anne Knowlton
Mitochondrial dynamics in heart failure.
Congestive heart failure (Greenwich, Conn.) 2011;17(6):257-61.
2011: Angela S Pechenino; John N Stallone; Xian-Min He; Alison R Lee; Li Lin; Fiona N Mbai; Anne Knowlton
Impact of aging vs. estrogen loss on cardiac gene expression: estrogen replacement and inflammation.
Physiological genomics 2011;43(18):1065-73.
2011: Samuel Kobba; Se-Chan Kim; Le Chen; Eunjung Kim; Alice L Tran; Pascal Knuefermann; Anne Knowlton
The heat shock paradox and cardiac myocytes: role of heat shock factor.
Shock (Augusta, Ga.) 2011;35(5):478-84.
2011: James P Stice; Le Chen; Se-Chan Kim; J S Jung; A L Tran; T T Liu; Anne Knowlton
17β-Estradiol, aging, inflammation, and the stress response in the female heart.
Endocrinology 2011;152(4):1589-98.
2011: R Michael Gower; Huaizhu Wu; Greg A Foster; Sridevi Devaraj; Ishwarlal Jialal; Christie M Ballantyne; Anne Knowlton; Scott I Simon
CD11c/CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(1):160-6.
2010: Dipika Tuteja; Sassan Rafizadeh; Valeriy Timofeyev; Shuyun Wang; Zheng Zhang; Ning Li; Robertino K Mateo; Anil Singapuri; J Nilas Young; Anne Knowlton; Nipavan Chiamvimonvat
Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.
Circulation research 2010;107(7):851-9.
2010: Simone Filosto; William Fry; Anne Knowlton; Tzipora Goldkorn
Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B).
The Journal of biological chemistry 2010;285(14):10213-22.
2010: L Chen; Anne Knowlton
Mitochondria and heart failure: new insights into an energetic problem.
Minerva cardioangiologica 2010;58(2):213-29.
2010: Y Wang; L Chen; Nobuko Hagiwara; Anne Knowlton
Regulation of heat shock protein 60 and 72 expression in the failing heart.
Journal of molecular and cellular cardiology 2010;48(2):360-6.
2009: Se-Chan Kim; James P Stice; Le Chen; James S Jung; Sanjiv Gupta; Yin Wang; Georg Baumgarten; JoAnn Trial; Anne Knowlton
Extracellular heat shock protein 60, cardiac myocytes, and apoptosis.
Circulation research 2009;105(12):1186-95.
2009: Le Chen; Qizhi Gong; James P Stice; Anne Knowlton
Mitochondrial OPA1, apoptosis, and heart failure.
Cardiovascular research 2009;84(1):91-9.
2009: James P Stice; Jennifer Shuwen Lee; Angela S Pechenino; Anne Knowlton
Estrogen, aging and the cardiovascular system.
Future cardiology 2009;5(1):93-103.
2009: James P Stice; Jason P Eiserich; Anne Knowlton
Role of aging versus the loss of estrogens in the reduction in vascular function in female rats.
Endocrinology 2009;150(1):212-9.
2008: Charles L Stebbins; James P Stice; C Michael Hart; Fiona N Mbai; Anne Knowlton
Effects of dietary decosahexaenoic acid (DHA) on eNOS in human coronary artery endothelial cells.
Journal of cardiovascular pharmacology and therapeutics 2008;13(4):261-8.
2008: James P Stice; Anne Knowlton
Estrogen, NFkappaB, and the heat shock response.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):517-27.
2008: Anne Knowlton; Uma Srivatsa
Heat-shock protein 60 and cardiovascular disease: a paradoxical role.
Future cardiology 2008;4(2):151-61.
2008: Karyn L Hamilton; Li Lin; Yin Wang; Anne Knowlton
Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression.
Physiological genomics 2008;32(2):254-63.
2007: Li Lin; S C Kim; Yin Wang; Sanjiv Gupta; B Davis; Scott I Simon; Guillermo Torre Amione; Anne Knowlton
HSP60 in heart failure: abnormal distribution and role in cardiac myocyte apoptosis.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2238-47.
2007: Sanjiv Gupta; Anne Knowlton
HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H3052-6.
2007: Harold J Ting; James P Stice; Ulrich Y Schaff; David Y Hui; John C Rutledge; Anne Knowlton; Anthony G Passerini; Scott I Simon
Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha.
Circulation research 2007;100(3):381-90.
2007: Ling Lu; Qian Zhang; Valeriy Timofeyev; Zhao Zhang; J Nilas Young; Hee-Sup Shin; Anne Knowlton; Nipavan Chiamvimonvat
Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.
Circulation research 2007;100(1):112-20.
2007: Se-Chan Kim; Alexander Ghanem; Heidi Stapel; Klaus Tiemann; Pascal Knuefermann; Andreas Hoeft; Rainer Meyer; Christian Grohé; Anne Knowlton; Georg Baumgarten
Toll-like receptor 4 deficiency: smaller infarcts, but no gain in function.
BMC physiology 2007;7():5.
2007: Anne Knowlton
Life, death, the unfolded protein response and apoptosis.
Cardiovascular research 2007;73(1):1-2.
2006: Georg Baumgarten; Pascal Knuefermann; Gerrit Schuhmacher; Volker Vervölgyi; Joscha von Rappard; Ulrike Dreiner; Klaus Fink; Chryso Djoufack; Andreas Hoeft; Christian Grohé; Anne Knowlton; Rainer Meyer
Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia.
Shock (Augusta, Ga.) 2006;25(1):43-9.
2006: Anne Knowlton
NFkappaB, heat shock proteins, HSF-1, and inflammation.
Cardiovascular research 2006;69(1):7-8.
2005: M R Voss; S Gupta; J P Stice; Georg Baumgarten; L Lu; J M Tristan; Anne Knowlton
Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.
American journal of physiology. Heart and circulatory physiology 2005;289(6):H2519-25.
2005: F N Mbai; Anne Knowlton
Aging, ischemia and the heart.
Journal of molecular and cellular cardiology 2005;38(2):241-4.
2005: Sanjiv Gupta; Anne Knowlton
HSP60, Bax, apoptosis and the heart.
Journal of cellular and molecular medicine 2005;9(1):51-8.
2004: Karyn L Hamilton; F N Mbai; S Gupta; Anne Knowlton
Estrogen, heat shock proteins, and NFkappaB in human vascular endothelium.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1628-33.
2004: JoAnn Trial; Roger Rossen; Jose Rubio; Anne Knowlton
Inflammation and ischemia: macrophages activated by fibronectin fragments enhance the survival of injured cardiac myocytes.
Experimental biology and medicine (Maywood, N.J.) 2004;229(6):538-45.
2004: Karyn L Hamilton; S Gupta; Anne Knowlton
Estrogen and regulation of heat shock protein expression in female cardiomyocytes: cross-talk with NF kappa B signaling.
Journal of molecular and cellular cardiology 2004;36(4):577-84.
2003: M R Voss; J N Stallone; Min Li; Richard N M Cornelussen; Pascal Knuefermann; Anne Knowlton
Gender differences in the expression of heat shock proteins: the effect of estrogen.
American journal of physiology. Heart and circulatory physiology 2003;285(2):H687-92.
2003: Ming Li; Michael Ittmann; David R Rowley; Anne Knowlton; Ajula Vaid; Daniel E Epner
Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer.
The Prostate 2003;56(2):98-105.
2003: Biykem Bozkurt; Ildiko Agoston; Anne Knowlton
Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines.
Journal of the American College of Cardiology 2003;41(2):211-4.
2003: Anne Knowlton; Sanjiv Gupta
HSP60, Bax, and cardiac apoptosis.
Cardiovascular toxicology 2003;3(3):263-8.
2002: S Gupta; Anne Knowlton
Cytosolic heat shock protein 60, hypoxia, and apoptosis.
Circulation 2002;106(21):2727-33.
2002: Richard N M Cornelussen; Anne Knowlton
Heme-oxygenase-1: versatile sentinel against injury.
Journal of molecular and cellular cardiology 2002;34(10):1297-1300.
2002: SR Kirchhoff; S Gupta; Anne Knowlton
Cytosolic heat shock protein 60, apoptosis, and myocardial injury.
Circulation 2002;105(24):2899-904.
2002: YH Wang; Anne Knowlton; F H Li; Steven C Borkan
Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells.
Cell stress & chaperones 2002;7(2):137-45.
2001: Richard N M Cornelussen; Frans A van Nieuwenhoven; Luc H E H Snoeckx; Anne Knowlton
Presence of heat shock protein 72 in cardiomyocytes after heat stress.
Circulation 2001;104(22):E123.
2001: M D Howell; Jane M Geraci; Anne Knowlton
Congestive heart failure and outpatient risk of venous thromboembolism: a retrospective, case-control study.
Journal of clinical epidemiology 2001;54(8):810-6.
2001: Richard N M Cornelussen; S Gupta; Anne Knowlton
Regulation of prostaglandin A1-induced heat shock protein expression in isolated cardiomyocytes.
Journal of molecular and cellular cardiology 2001;33(8):1447-54.
2001: J Chang; JS Wasser; Richard N M Cornelussen; Anne Knowlton
Activation of heat-shock factor by stretch-activated channels in rat hearts.
Circulation 2001;104(2):209-14.
2001: Anne Knowlton
Mutation of amino acids 566-572 (KKKVLDK) inhibits nuclear accumulation of heat shock protein 72 after heat shock.
Journal of molecular and cellular cardiology 2001;33(1):49-55.
2001: Anne Knowlton; L Sun
Heat-shock factor-1, steroid hormones, and regulation of heat-shock protein expression in the heart.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H455-64.
2001: J Chang; Anne Knowlton; F Xu; JS Wasser
Activation of the heat shock response: relationship to energy metabolites. A (31)P NMR study in rat hearts.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H426-33.
2000: Jane M Geraci; Anne Knowlton
Spironolactone for heart failure: spiraling out of control.
Chest 2000;118(6):1522-3.
2000: Anne Knowlton; M Grenier; SR Kirchhoff; M Salfity
Phosphorylation at tyrosine-524 influences nuclear accumulation of HSP72 with heat stress.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H2143-9.
2000: L Sun; J Chang; SR Kirchhoff; Anne Knowlton
Activation of HSF and selective increase in heat-shock proteins by acute dexamethasone treatment.
American journal of physiology. Heart and circulatory physiology 2000;278(4):H1091-7.
2000: J Chang; Anne Knowlton; JS Wasser
Expression of heat shock proteins in turtle and mammal hearts: relationship to anoxia tolerance.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(1):R209-14.
1999: Yihan Wang; Anne Knowlton; T G Christensen; T Shih; Steven C Borkan
Prior heat stress inhibits apoptosis in adenosine triphosphate-depleted renal tubular cells.
Kidney international 1999;55(6):2224-35.
1999: Anne Knowlton
Mutation of amino acids 246-251 alters nuclear accumulation of human heat shock protein (HSP) 72 with stress, but does not reduce viability.
Journal of molecular and cellular cardiology 1999;31(3):523-32.
1998: M Nakano; Anne Knowlton; Ziad I Dibbs; Douglas L Mann
Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte.
Circulation 1998;97(14):1392-400.
1998: Anne Knowlton; S Kapadia; Guillermo Torre Amione; Jean-Bernard Durand; R Bies; J Young; Douglas L Mann
Differential expression of heat shock proteins in normal and failing human hearts.
Journal of molecular and cellular cardiology 1998;30(4):811-8.
1997: M Nakano; D L Mann; Anne Knowlton
Blocking the endogenous increase in HSP 72 increases susceptibility to hypoxia and reoxygenation in isolated adult feline cardiocytes.
Circulation 1997;95(6):1523-31.
1996: M Nakano; Anne Knowlton; T Yokoyama; W Lesslauer; D L Mann
Tumor necrosis factor-alpha-induced expression of heat shock protein 72 in adult feline cardiac myocytes.
The American journal of physiology 1996;270(4 Pt 2):H1231-9.
1995: J Z Sun; Xian-Liang Tang; Anne Knowlton; S W Park; Y Qiu; Roberto Bolli
Late preconditioning against myocardial stunning. An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs.
The Journal of clinical investigation 1995;95(1):388-403.
1995: Anne Knowlton
Current concepts in transcription, translation, and the regulation of gene expression. A primer for the clinician.
Chest 1995;107(1):241-8.
1995: Anne Knowlton
The role of heat shock proteins in the heart.
Journal of molecular and cellular cardiology 1995;27(1):121-31.
1994: Anne Knowlton
Heat-shock proteins, stress, and the heart.
Annals of the New York Academy of Sciences 1994;723():128-37.
1992: Anne Knowlton; C M Connelly; G M Romo; W Mamuya; Carl S Apstein; Peter Brecher
Rapid expression of fibronectin in the rabbit heart after myocardial infarction with and without reperfusion.
The Journal of clinical investigation 1992;89(4):1060-8.
1991: Anne Knowlton; Franz R Eberli; Peter Brecher; G M Romo; A Owen; Carl S Apstein
A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.
The Journal of clinical investigation 1991;88(6):2018-25.
1991: Anne Knowlton; Peter Brecher; Carl S Apstein
Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.
The Journal of clinical investigation 1991;87(1):139-47.
1990: Anne Knowlton; R H Falk
Paradoxical increase in heart rate before conversion to sinus rhythm in patients with recent-onset atrial fibrillation.
The American journal of cardiology 1990;65(13):930-2.
1989: Anne Knowlton; R E Burrier; Peter Brecher
Rabbit heart fatty acid-binding protein. Isolation, characterization, and application of a monoclonal antibody.
Circulation research 1989;65(4):981-8.
1989: Anne Knowlton; Carl S Apstein; R Saouf; Peter Brecher
Leakage of heart fatty acid binding protein with ischemia and reperfusion in the rat.
Journal of molecular and cellular cardiology 1989;21(6):577-83.
1988: S E Wiegers; J F Plehn; A Rajail-Khorasani; Anne Knowlton
Purulent pericarditis and ventricular pseudoaneurysm in an intravenous drug abuser.
American heart journal 1988;116(6 Pt 1):1635-7.
1988: R H Falk; Anne Knowlton; N J Battinelli
The effect of propranolol and verapamil on external pacing threshold: a placebo-controlled study.
Pacing and clinical electrophysiology : PACE 1988;11(10):1439-43.
1988: R H Falk; Anne Knowlton; S Manaker
Verapamil-induced atrial fibrillation.
The New England journal of medicine 1988;318(10):640-1.
1987: R H Falk; Anne Knowlton
Atypical ventricular tachycardia or motion artifact?
The American journal of cardiology 1987;59(8):924.
1987: R H Falk; Anne Knowlton; Sheilah A Bernard; N E Gotlieb; N J Battinelli
Digoxin for converting recent-onset atrial fibrillation to sinus rhythm. A randomized, double-blinded trial.
Annals of internal medicine 1987;106(4):503-6.
1986: Anne Knowlton; R H Falk
External cardiac pacing during in-hospital cardiac arrest.
The American journal of cardiology 1986;57(15):1295-8.