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MOON-IL KANG

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Disorders

Oxidative Stress

Concepts & Ideas

Anatomy

Phenomena

Protein Binding

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Publications

TOP 3
Balasundaram Padmanabhan; Kit I Tong; Tsutomu Ohta; Yoshihiro Nakamura; Maria Scharlock; Makiko Ohtsuji; MOON-IL KANG; Akira Kobayashi; Shigeyuki Yokoyama; Masayuki Yamamoto
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Akira Kobayashi; MOON-IL KANG; Yoriko Watai; Kit I Tong; Takahiro Shibata; Koji Uchida; Masayuki Yamamoto
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.
Tomonori Hosoya; Atsushi Maruyama; MOON-IL KANG; Yukie Kawatani; Takahiro Shibata; Koji Uchida; Eiji Warabi; Noriko Noguchi; Ken Itoh; Masayuki Yamamoto
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells.

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All Publications

2006: Balasundaram Padmanabhan; Kit I Tong; Tsutomu Ohta; Yoshihiro Nakamura; Maria Scharlock; Makiko Ohtsuji; MOON-IL KANG; Akira Kobayashi; Shigeyuki Yokoyama; Masayuki Yamamoto
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Molecular cell 2006;21(5):689-700.
2006: Akira Kobayashi; MOON-IL KANG; Yoriko Watai; Kit I Tong; Takahiro Shibata; Koji Uchida; Masayuki Yamamoto
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.
Molecular and cellular biology 2006;26(1):221-9.
2005: Tomonori Hosoya; Atsushi Maruyama; MOON-IL KANG; Yukie Kawatani; Takahiro Shibata; Koji Uchida; Eiji Warabi; Noriko Noguchi; Ken Itoh; Masayuki Yamamoto
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells.
The Journal of biological chemistry 2005;280(29):27244-50.
2005: Yasutake Katoh; Katsuyuki Iida; MOON-IL KANG; Akira Kobayashi; Mio Mizukami; Kit I Tong; Michael McMahon; John D Hayes; Ken Itoh; Masayuki Yamamoto
Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
Archives of biochemistry and biophysics 2005;433(2):342-50.
2005: Balasundaram Padmanabhan; Maria Scharlock; Kit I Tong; Yoshihiro Nakamura; MOON-IL KANG; Akira Kobayashi; Takehisa Matsumoto; Akiko Tanaka; Masayuki Yamamoto; Shigeyuki Yokoyama
Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):153-5.
2004: Akira Kobayashi; MOON-IL KANG; Hiromi Okawa; Makiko Ohtsuji; Yukari Zenke; Tomoki Chiba; Kazuhiko Igarashi; Masayuki Yamamoto
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Molecular and cellular biology 2004;24(16):7130-9.
2004: MOON-IL KANG; Akira Kobayashi; Nobunao Wakabayashi; Sang Geon Kim; Masayuki Yamamoto
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2046-51.
2004: Nobunao Wakabayashi; Albena T Dinkova-Kostova; W David Holtzclaw; MOON-IL KANG; Akira Kobayashi; Masayuki Yamamoto; Thomas W Kensler; Paul Talalay
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2040-5.