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Philippe Touraine

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Disorders

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Physiology

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Publications

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Adela Voican; Marc Lombès; Philippe Touraine; Anne Bachelot; Jérôme BOULIGAND; Jérôme Dulon; Bruno Francou; Anne Guiochon-Mantel
NR5A1 (SF-1) Mutations Are Not a Major Cause of Primary Ovarian Insufficiency.
Anne Bachelot; Yasmina Badachi; Zeina Chakhtoura; Beny Charbit; Mathieu Coudert; Christiane Coussieu; Jérome Dulon; Geneviève Plu-Bureau; Philippe Touraine
Influence of hormonal control on LH pulsatility and secretion in women with classical congenital adrenal hyperplasia.
Bruno Donadille; Lise Duranteau; Laurence Iserin; Guillaume Jondeau; Yves Lebouc; Juliane Léger; Catherine Meuleman; Laurence Monnier-Cholley; Michel Polak; Alexandra Rousseau; Sylvie Salenave; Dinane Samara-Boustani; Philippe Touraine; Delphine Zenaty; Damien Bonnet; Philippe Bouchard; Nathalie Bourcigaux; Laure Cabanes; Sylvie Cabrol; Jean-Claude Carel; Philippe Chanson; Carine Courtillot; Sophie Christin-Maitre
Cardiovascular findings and management in Turner syndrome: insights from a French cohort.

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All Publications

2013: Adela Voican; Marc Lombès; Philippe Touraine; Anne Bachelot; Jérôme BOULIGAND; Jérôme Dulon; Bruno Francou; Anne Guiochon-Mantel
NR5A1 (SF-1) Mutations Are Not a Major Cause of Primary Ovarian Insufficiency.
The Journal of clinical endocrinology and metabolism 2013;98(5):E1017-21.
2012: Anne Bachelot; Yasmina Badachi; Zeina Chakhtoura; Beny Charbit; Mathieu Coudert; Christiane Coussieu; Jérome Dulon; Geneviève Plu-Bureau; Philippe Touraine
Influence of hormonal control on LH pulsatility and secretion in women with classical congenital adrenal hyperplasia.
European journal of endocrinology / European Federation of Endocrine Societies 2012;167(4):499-505.
2012: Bruno Donadille; Lise Duranteau; Laurence Iserin; Guillaume Jondeau; Yves Lebouc; Juliane Léger; Catherine Meuleman; Laurence Monnier-Cholley; Michel Polak; Alexandra Rousseau; Sylvie Salenave; Dinane Samara-Boustani; Philippe Touraine; Delphine Zenaty; Damien Bonnet; Philippe Bouchard; Nathalie Bourcigaux; Laure Cabanes; Sylvie Cabrol; Jean-Claude Carel; Philippe Chanson; Carine Courtillot; Sophie Christin-Maitre
Cardiovascular findings and management in Turner syndrome: insights from a French cohort.
European journal of endocrinology / European Federation of Endocrine Societies 2012;167(4):517-22.
2012: Alain Gautier; Ariane Godbout; Catherine Grosheny; Christel Jublanc; Jean-Yves Poirier; Laurent Riffaud; Christian Sainte-Rose; Isabelle Tejedor; Philippe Touraine; Remy Van Effenterre; Fabrice Bonnet; Gilles Brassier; Mathieu Coudert; Carine Courtillot; Marc De Kerdanet
Markers of recurrence and long-term morbidity in craniopharyngioma: a systematic analysis of 171 patients.
The Journal of clinical endocrinology and metabolism 2012;97(4):1258-67.
2011: Maud Bidet; Estelle Bissauge; Christiane Coussieu; Jérôme Dulon; Jean-Louis Golmard; Solenne Gricourt; Anne Bachelot; Yasmina Badachi; Philippe Touraine
Resumption of ovarian function and pregnancies in 358 patients with premature ovarian failure.
The Journal of clinical endocrinology and metabolism 2011;96(12):3864-72.
2011: Julie Sarfati; Philippe Touraine; Anne Bachelot; Christiane Coussieu; Géri Meduri
Impact of clinical, hormonal, radiological, and immunohistochemical studies on the diagnosis of postmenopausal hyperandrogenism.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(5):779-88.
2011: Justine Bouilly; Isabelle Broutin; Philippe Touraine; Anne Bachelot; Nadine Binart
Novel NOBOX loss-of-function mutations account for 6.2% of cases in a large primary ovarian insufficiency cohort.
Human mutation 2011;32(10):1108-13.
2010: Anne Bachelot; Justine Bouilly; Yuchen Liu; Diane Rebourcet; Céline Leux; Frédérique Kuttenn; Philippe Touraine; Nadine Binart
Sequence variation analysis of the prolactin receptor C-terminal region in women with premature ovarian failure.
Fertility and sterility 2010;94(7):2772-5.
2010: Géri Méduri; Carine Courtillot; Olivier Lahuna; Frédérique Kuttenn; Philippe Touraine; Micheline Misrahi
[Normal spermatogenesis in a patient with mutant luteinizing hormone].
Médecine sciences : M/S 2010;26(8-9):690-3.
2010: I Fernandez; Philippe Touraine; Vincent Goffin
Prolactin and human tumourogenesis.
Journal of neuroendocrinology 2010;22(7):771-7.
2010: Sophie Bernichtein; Philippe Touraine; Vincent Goffin
New concepts in prolactin biology.
The Journal of endocrinology 2010;206(1):1-11.
2010: Philippe Touraine
[Phenotype-genotype correlation in mutations of the gonadotrophin receptor gene in women].
Annales d'endocrinologie 2010;71(3):203-5.
2010: Maud Bidet; Christine Bellanné-Chantelot; Marie-Béatrice Galand-Portier; Jean-Louis Golmard; Véronique Tardy; Yves Morel; Séverine Clauin; Christiane Coussieu; Philippe Boudou; Irene Mowzowicz; Anne Bachelot; Philippe Touraine; Frédérique Kuttenn
Fertility in women with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 2010;95(3):1182-90.
2010: Vincent Goffin; Roman Bogorad; Philippe Touraine
Identification of gain-of-function variants of the human prolactin receptor.
Methods in enzymology 2010;484():329-55.
2010: Anne Bachelot; Zeina Chakhtoura; Dinane Samara-Boustani; Jérome Dulon; Philippe Touraine; Michel Polak
Bone health should be an important concern in the care of patients affected by 21 hydroxylase deficiency.
International journal of pediatric endocrinology 2010;2010():.
2010: Carine Courtillot; Zeina Chakhtoura; Roman Bogorad; Catherine Genestie; Sophie Bernichtein; Yasmina Badachi; Gilbert Janaud; Jean-Pierre Akakpo; Anne Bachelot; Frédérique Kuttenn; Vincent Goffin; Philippe Touraine
Characterization of two constitutively active prolactin receptor variants in a cohort of 95 women with multiple breast fibroadenomas.
The Journal of clinical endocrinology and metabolism 2010;95(1):271-9.
2010: Géri Méduri; Anne Bachelot; Catherine Duflos; Bettina Bständig; Catherine Poirot; Catherine Genestie; Reiner A Veitia; Elfride De Baere; Philippe Touraine
FOXL2 mutations lead to different ovarian phenotypes in BPES patients: Case Report.
Human reproduction (Oxford, England) 2010;25(1):235-43.
2009: Caroline Achard; Carine Courtillot; Olivier Lahuna; Géri Méduri; Jean-Claude Soufir; Philippe Lière; Anne Bachelot; Hassani Benyounes; Michael Schumacher; Frédérique Kuttenn; Philippe Touraine; Micheline Misrahi
Normal spermatogenesis in a man with mutant luteinizing hormone.
The New England journal of medicine 2009;361(19):1856-63.
2009: Anne Bachelot; Agnès Rouxel; Nathalie Massin; Jérome Dulon; Carine Courtillot; Christine Matuchansky; Yasmina Badachi; Anne Fortin; Bernard Paniel; Fabrice Lecuru; Marie-Aude Lefrère-Belda; Elisabeth Constancis; Elisabeth Thibault; Géri Meduri; Anne Guiochon-Mantel; Micheline Misrahi; Frédérique Kuttenn; Philippe Touraine
Phenotyping and genetic studies of 357 consecutive patients presenting with premature ovarian failure.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(1):179-87.
2008: Roman Bogorad; Carine Courtillot; Chidi Mestayer; Sophie Bernichtein; Lilya Harutyunyan; Jean-Baptiste Jomain; Anne Bachelot; Frédérique Kuttenn; Paul A Kelly; Vincent Goffin; Philippe Touraine
Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14533-8.
2008: Maud Bidet; Anne Bachelot; Philippe Touraine
Premature ovarian failure: predictability of intermittent ovarian function and response to ovulation induction agents.
Current opinion in obstetrics & gynecology 2008;20(4):416-20.
2008: Zeina Chakhtoura; Anne Bachelot; Dinane Samara-Boustani; Jean-Charles Ruiz; Bruno Donadille; Jérôme Dulon; Sophie Christin-Maître; Claire Bouvattier; Marie-Charles Raux-Demay; Philippe Bouchard; Jean-Claude Carel; Juliane Leger; Frédérique Kuttenn; Michel Polak; Philippe Touraine
Impact of total cumulative glucocorticoid dose on bone mineral density in patients with 21-hydroxylase deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(6):879-87.
2008: C Courtillot; Philippe Touraine
[Management of families at high risk for hereditary breast-ovarian cancers: the endocrinologist's point of view].
Annales d'endocrinologie 2008;69(3):193-200.
2008: Geri Meduri; Anne Bachelot; M P Cocca; Claudine Vasseur; Patrice Rodien; Frédérique Kuttenn; Philippe Touraine; Micheline Misrahi
Molecular pathology of the FSH receptor: new insights into FSH physiology.
Molecular and cellular endocrinology 2008;282(1-2):130-42.
2008: Nathalie Massin; G Méduri; Anne Bachelot; Micheline Misrahi; Frédérique Kuttenn; Philippe Touraine
Evaluation of different markers of the ovarian reserve in patients presenting with premature ovarian failure.
Molecular and cellular endocrinology 2008;282(1-2):95-100.
2008: Anne Bachelot; Zeina Chakthoura; Agnès Rouxel; Jérome Dulon; Philippe Touraine
Classical forms of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in adults.
Hormone research 2008;69(4):203-11.
2008: Béatrice Mandon-Pépin; Philippe Touraine; Frédérique Kuttenn; Céline Derbois; Agnes Rouxel; Fumihiko MATSUDA; Alain Nicolas; Corinne Cotinot; Marc Fellous
Genetic investigation of four meiotic genes in women with premature ovarian failure.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(1):107-15.
2007: Philippe Touraine
[Amenorrhoea].
La Revue du praticien 2007;57(16):1829-36.
2007: Anne Bachelot; Kathleen Laborde; Jean-Louis Bresson; Geneviève Plu-Bureau; A Raynaud; X Bertagna; Agnès Mogenet; M Mansour; V Lucas-Jouy; J-P Gayno; Yves Reznik; Jean-Marc Kuhn; L Billaud; MC Vacher-Lavenu; M Putterman; Irène Mowszowicz; Philippe Touraine; Frédérique Kuttenn
Luteinizing hormone pulsatility in patients with major ovarian hyperandrogenism.
Journal of endocrinological investigation 2007;30(8):636-46.
2007: Anne Bachelot; Z Chakhtoura; A Rouxel; J Dulon; Philippe Touraine
Hormonal treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Annales d'endocrinologie 2007;68(4):274-80.
2007: Anne Bachelot; Geneviève Plu-Bureau; Elisabeth Thibaud; Kathleen Laborde; Graziella Pinto; Dinane Samara; Claire Nihoul-Fékété; Frédérique Kuttenn; Michel Polak; Philippe Touraine
Long-term outcome of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Hormone research 2007;67(6):268-76.
2007: Géri Méduri; Nathalie Massin; Jean Guibourdenche; Anne Bachelot; O Fiori; Frédérique Kuttenn; Micheline Misrahi; Philippe Touraine
Serum anti-Müllerian hormone expression in women with premature ovarian failure.
Human reproduction (Oxford, England) 2007;22(1):117-23.
2006: David Piwnica; Isabelle Fernandez; Nadine Binart; Philippe Touraine; Paul A Kelly; Vincent Goffin
A new mechanism for prolactin processing into 16K PRL by secreted cathepsin D.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3263-78.
2006: Paul Laissue; Sophie Christin-Maitre; Philippe Touraine; Frédérique Kuttenn; Olli Ritvos; Kristiina Aittomaki; Nathalie Bourcigaux; Laetitia Jacquesson; Philippe Bouchard; René Frydman; Didier Dewailly; Anne-Céline Reyss; Luke Jeffery; Anne Bachelot; Nathalie Massin; Marc Fellous; Reiner A Veitia
Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(5):739-44.
2006: Nathalie Massin; C Czernichow; Elisabeth Thibaud; Frédérique Kuttenn; Michel Polak; Philippe Touraine
Idiopathic premature ovarian failure in 63 young women.
Hormone research 2006;65(2):89-95.
2005: Carine Courtillot; Geneviève Plu-Bureau; Nadine Binart; Corinne Balleyguier; Brigitte Sigal-Zafrani; Vincent Goffin; Frédérique Kuttenn; Paul A Kelly; Philippe Touraine
Benign breast diseases.
Journal of mammary gland biology and neoplasia 2005;10(4):325-35.
2005: Philippe Touraine; N Youssef; M A Alyanakian; X Lechat; Corinne Balleyguier; C Duflos; A Dib; A May; J C Carel; Kathleen Laborde; Brigitte Sigal-Zafrani; Vincent Goffin; B Eymard; Christian Boitard; N Brousse; Frédérique Kuttenn
Breast inflammatory gigantomastia in a context of immune-mediated diseases.
The Journal of clinical endocrinology and metabolism 2005;90(9):5287-94.
2005: Anne Bachelot; Carine Courtillot; Philippe Touraine
[When and how should hyperprolactinemia be treated?].
Presse médicale (Paris, France : 1983) 2005;34(10):731-7.
2005: Vincent Goffin; Sophie Bernichtein; Philippe Touraine; Paul A Kelly
Development and potential clinical uses of human prolactin receptor antagonists.
Endocrine reviews 2005;26(3):400-22.
2005: Anne Bachelot; Geri Meduri; Nathalie Massin; Micheline Misrahi; Frédérique Kuttenn; Philippe Touraine
Ovarian steroidogenesis and serum androgen levels in patients with premature ovarian failure.
The Journal of clinical endocrinology and metabolism 2005;90(4):2391-6.
2004: Nathalie Massin; A Gougeon; Geri Meduri; Elisabeth Thibaud; Kathleen Laborde; C Matuchansky; E Constancis; MC Vacher-Lavenu; Bernard-Jean Paniel; J R Zorn; Micheline Misrahi; Frédérique Kuttenn; Philippe Touraine
Significance of ovarian histology in the management of patients presenting a premature ovarian failure.
Human reproduction (Oxford, England) 2004;19(11):2555-60.
2004: David Piwnica; Philippe Touraine; Ingrid Struman; Sebastien Tabruyn; Gérard Bolbach; Carmen Clapp; Joseph A Martial; Paul A Kelly; Vincent Goffin
Cathepsin D processes human prolactin into multiple 16K-like N-terminal fragments: study of their antiangiogenic properties and physiological relevance.
Molecular endocrinology (Baltimore, Md.) 2004;18(10):2522-42.
2004: Anne Bachelot; Geri Meduri; Eric Baudin; Frédérique Kuttenn; Philippe Touraine
Hyperandrogenism in a postmenopausal woman presenting with a metastatic ileum endocrine tumor.
Fertility and sterility 2004;81(3):675-8.
2003: Geri Meduri; Philippe Touraine; Isabelle Beau; Olivier Lahuna; Agnès Desroches; MC Vacher-Lavenu; Frédérique Kuttenn; Micheline Misrahi
Delayed puberty and primary amenorrhea associated with a novel mutation of the human follicle-stimulating hormone receptor: clinical, histological, and molecular studies.
The Journal of clinical endocrinology and metabolism 2003;88(8):3491-8.
2003: Nathalie Massin; Christophe Pêcheux; Corinne Eloit; Jean-Louis Bensimon; Julie Galey; Frédérique Kuttenn; Jean-Pierre Hardelin; Catherine Dodé; Philippe Touraine
X chromosome-linked Kallmann syndrome: clinical heterogeneity in three siblings carrying an intragenic deletion of the KAL-1 gene.
The Journal of clinical endocrinology and metabolism 2003;88(5):2003-8.
2002: Vincent Goffin; Nadine Binart; Philippe Touraine; Paul A Kelly
Prolactin: the new biology of an old hormone.
Annual review of physiology 2002;64():47-67.
2001: Philippe Touraine; Geneviève Plu-Bureau; N Beressi; P Decq; Jean-Christophe Thalabard; Frédérique Kuttenn
Resumption of luteinizing hormone pulsatility and hypogonadotropic hypogonadism after endoscopic ventriculocisternostomy in a hydrocephalic patient.
Fertility and sterility 2001;76(2):390-3.
2001: Philippe Touraine; Geneviève Plu-Bureau; C Beji; Pierre Mauvais-Jarvis; Frédérique Kuttenn
Long-term follow-up of 246 hyperprolactinemic patients.
Acta obstetricia et gynecologica Scandinavica 2001;80(2):162-8.
2000: M Llovera; C Pichard; Sophie Bernichtein; Sébastien Jeay; Philippe Touraine; Paul A Kelly; Vincent Goffin
Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation.
Oncogene 2000;19(41):4695-705.
2000: M Llovera; Philippe Touraine; Paul A Kelly; Vincent Goffin
Involvement of prolactin in breast cancer: redefining the molecular targets.
Experimental gerontology 2000;35(1):41-51.
1999: Vincent Goffin; Nadine Binart; Philippe Clément-Lacroix; B Bouchard; C Bole-Feysot; Marc Edery; B K Lucas; Philippe Touraine; A Pezet; R Maaskant; C Pichard; C Helloco; Nathalie Baran; H Favre; Sophie Bernichtein; A Allamando; Christopher J Ormandy; Paul A Kelly
From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models.
Genetic analysis : biomolecular engineering 1999;15(3-5):189-201.
1999: Philippe Touraine; Isabelle Beau; A Gougeon; Geri Meduri; Agnès Desroches; C Pichard; M Detoeuf; Bernard-Jean Paniel; M Prieur; J R Zorn; Edwin Milgrom; Frédérique Kuttenn; Micheline Misrahi
New natural inactivating mutations of the follicle-stimulating hormone receptor: correlations between receptor function and phenotype.
Molecular endocrinology (Baltimore, Md.) 1999;13(11):1844-54.
1999: Vincent Goffin; Philippe Touraine; C Pichard; Sophie Bernichtein; Paul A Kelly
Should prolactin be reconsidered as a therapeutic target in human breast cancer?
Molecular and cellular endocrinology 1999;151(1-2):79-87.
1999: C Deneux; Philippe Touraine; Frédérique Kuttenn
[Physiopathology of gonadotropic control of gametogenesis].
Annales de biologie clinique 1999;57(3):318-21.
1999: H Bry-Gauillard; Philippe Touraine; M F Mamzer-Bruneel; A Simoes-Vaz; Frédérique Kuttenn; C Legendre
Complete regression of a major hyperprolactinaemia after renal transplantation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(2):466-8.
1998: Philippe Touraine; C Deneux; Geneviève Plu-Bureau; Pierre Mauvais-Jarvis; Frédérique Kuttenn
Hormonal replacement therapy in menopausal women with a history of hyperprolactinemia.
Journal of endocrinological investigation 1998;21(11):732-6.
1998: Isabelle Beau; Philippe Touraine; Geri Meduri; A Gougeon; Agnès Desroches; C Matuchansky; Edwin Milgrom; Frédérique Kuttenn; Micheline Misrahi
A novel phenotype related to partial loss of function mutations of the follicle stimulating hormone receptor.
The Journal of clinical investigation 1998;102(7):1352-9.
1998: Sophie Christin-Maitre; C Rongières-Bertrand; Marie-Laure Kottler; N Lahlou; René Frydman; Philippe Touraine; Philippe Bouchard
A spontaneous and severe hyperstimulation of the ovaries revealing a gonadotroph adenoma.
The Journal of clinical endocrinology and metabolism 1998;83(10):3450-3.
1998: Vincent Goffin; B Bouchard; Christopher J Ormandy; E Weimann; F Ferrag; Philippe Touraine; C Bole-Feysot; R A Maaskant; P Clement-Lacroix; Marc Edery; Nadine Binart; Paul A Kelly
Prolactin: a hormone at the crossroads of neuroimmunoendocrinology.
Annals of the New York Academy of Sciences 1998;840():498-509.
1998: Philippe Touraine; JF Martini; Brigitte Zafrani; Jean-Claude Durand; F Labaille; Catherine Malet; Alain Nicolas; C Trivin; Marie Catherine Postel-Vinay; Frédérique Kuttenn; Paul A Kelly
Increased expression of prolactin receptor gene assessed by quantitative polymerase chain reaction in human breast tumors versus normal breast tissues.
The Journal of clinical endocrinology and metabolism 1998;83(2):667-74.
1997: Philippe Touraine; Frédérique Kuttenn
[Secondary amenorrhea. Diagnostic orientation].
La Revue du praticien 1997;47(18):2055-60.
1997: H Dollfus; S Gomberg; Philippe Touraine; Christophe Orssaud; M Hamdani; P Derome; Frédérique Kuttenn; J L Dufier
Unusual scotomas after transsphenoidal surgery of a pituitary macroadenoma.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 1997;17(3):204-6.
1994: F Ferrag; J J Lebrun; Philippe Touraine; M Nagano; M Dardenne; Paul A Kelly
Prolactin and the immune system.
ImmunoMethods 1994;5(1):21-30.