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Luc Brunsveld
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Research Profile (preview)
Concepts & Ideas
Chemicals & Drugs
Physiology
Phenomena
Procedures
Occupations
Genes & Molecular Sequences
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Network (preview)
13
Waldmann, Herbert
8
Alexandrov, Kirill
7
Goody, Roger
6
Meijer, EW
5
Durek, Thomas
4
Sijbesma, Rint
4
Watzke, Anja
3
Rak, Alexey
3
Prince, Ryan
3
Kuhlmann, Jürgen
3
Hirschberg, Ky
2
Kushnir, Susanna
2
Folmer, BJ
2
Pylypenko, Olena
2
Moore, Jeffrey
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Geonetwork of Luc Brunsveld (preview)
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All Publications
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2009: Vaz Belen; Möcklinghoff Sabine; Folkertsma Simon; Lusher Scott; de Vlieg Jacob; Brunsveld Luc
Computational design, synthesis, and evaluation of miniproteins as androgen receptor coactivator mimics.
Chemical communications (Cambridge, England) 2009;(36):5377-9.
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2009: Uhlenheuer Dana A; Wasserberg Dorothee; Nguyen Hoang; Zhang Li; Blum Christian; Subramaniam Vinod; Brunsveld Luc
Modulation of protein dimerization by a supramolecular host-guest system.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(35):8779-90.
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2009: Renner Steffen; van Otterlo Willem A L; Dominguez Seoane Marta; Möcklinghoff Sabine; Hofmann Bettina; Wetzel Stefan; Schuffenhauer Ansgar; Ertl Peter; Oprea Tudor I; Steinhilber Dieter; Brunsveld Luc; Rauh Daniel; Waldmann Herbert
Bioactivity-guided mapping and navigation of chemical space.
Nature chemical biology 2009;5(8):585-92.
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2009: Carraz Maëlle; Zwart Wilbert; Phan Trang; Michalides Rob; Brunsveld Luc
Perturbation of estrogen receptor alpha localization with synthetic nona-arginine LXXLL-peptide coactivator binding inhibitors.
Chemistry & biology 2009;16(7):702-11.
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2009: Weise Katrin; Triola Gemma; Brunsveld Luc; Waldmann Herbert; Winter Roland
Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains.
Journal of the American Chemical Society 2009;131(4):1557-64.
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2009: Alexander Michael; Gerauer Marc; Pechlivanis Markos; Popkirova Boriana; Dvorsky Radovan; Brunsveld Luc; Waldmann Herbert; Kuhlmann Jürgen
Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein.
Chembiochem : a European journal of chemical biology 2009;10(1):98-108.
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2009: Brunsveld Luc; Waldmann Herbert; Huster Daniel
Membrane binding of lipidated Ras peptides and proteins--the structural point of view.
Biochimica et biophysica acta 2009;1788(1):273-88.
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2009: Müller Marion K; Brunsveld Luc
A supramolecular polymer as a self-assembling polyvalent scaffold.
Angewandte Chemie (International ed. in English) 2009;48(16):2921-4.
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2008: Vaz Esther; Pomerantz William C; Geyer Matthias; Gellman Samuel H; Brunsveld Luc
Comparison of design strategies for promotion of beta-peptide 14-helix stability in water.
Chembiochem : a European journal of chemical biology 2008;9(14):2254-9.
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2008: Guo Zhong; Wu Yao-Wen; Das Debapratim; Delon Christine; Cramer Janinna; Yu Shen; Thuns Sandra; Lupilova Nataliya; Waldmann Herbert; Brunsveld Luc; Goody Roger S; Alexandrov Kirill; Blankenfeldt Wulf
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.
The EMBO journal 2008;27(18):2444-56.
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2008: Vaz Belén; Brunsveld Luc
Stable helical peptoids via covalent side chain to side chain cyclization.
Organic & biomolecular chemistry 2008;6(16):2988-94.
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2008: Triola Gemma; Brunsveld Luc; Waldmann Herbert
Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction.
The Journal of organic chemistry 2008;73(9):3646-9.
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2007: Wu Yao-Wen; Alexandrov Kirill; Brunsveld Luc
Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase.
Nature protocols 2007;2(11):2704-11.
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2007: Zhang Li; Wu Yaowen; Brunsveld Luc
A synthetic supramolecular construct modulating protein assembly in cells.
Angewandte Chemie (International ed. in English) 2007;46(11):1798-802.
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2006: Brunsveld Luc; Kuhlmann Jürgen; Alexandrov Kirill; Wittinghofer Alfred; Goody Roger S; Waldmann Herbert
Lipidated ras and rab peptides and proteins--synthesis, structure, and function.
Angewandte Chemie (International ed. in English) 2006;45(40):6622-46.
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2006: Brunsveld L; Kuhlmann J; Waldmann H
Synthesis of palmitoylated Ras-peptides and -proteins.
Methods (San Diego, Calif.) 2006;40(2):151-65.
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2006: Gelb Michael H; Brunsveld Lucas; Hrycyna Christine A; Michaelis Susan; Tamanoi Fuyuhiko; Van Voorhis Wesley C; Waldmann Herbert
Therapeutic intervention based on protein prenylation and associated modifications.
Nature chemical biology 2006;2(10):518-28.
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2006: Vaz Esther; Brunsveld Luc
Stable helical beta 3-peptides in water via covalent bridging of side chains.
Organic letters 2006;8(19):4199-202.
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2006: Pylypenko Olena; Rak Alexey; Durek Thomas; Kushnir Susanna; Dursina Beatrice E; Thomae Nicolas H; Constantinescu Alexandru T; Brunsveld Luc; Watzke Anja; Waldmann Herbert; Goody Roger S; Alexandrov Kirill
Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling.
The EMBO journal 2006;25(1):13-23.
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2005: Watzke Anja; Brunsveld Luc; Durek Thomas; Alexandrov Kirill; Rak Alexey; Goody Roger S; Waldmann Herbert
Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases.
Organic & biomolecular chemistry 2005;3(7):1157-64.
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2005: Brunsveld Luc; Watzke Anja; Durek Thomas; Alexandrov Kirill; Goody Roger S; Waldmann Herbert
Synthesis of functionalized rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligation.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(9):2756-72.
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2005: Goody Roger S; Durek Thomas; Waldmann Herbert; Brunsveld Lucas; Alexandrov Kirill
Application of protein semisynthesis for the construction of functionalized posttranslationally modified rab GTPases.
Methods in enzymology 2005;403():29-42.
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2004: Marcos Ramos Alicia; Meskers Stefan C J; Beckers Edwin H A; Prince Ryan B; Brunsveld Luc; Janssen René A J
Supramolecular control over donor-acceptor photoinduced charge separation.
Journal of the American Chemical Society 2004;126(31):9630-44.
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2003: Rak Alexey; Pylypenko Olena; Durek Thomas; Watzke Anja; Kushnir Susanna; Brunsveld Lucas; Waldmann Herbert; Goody Roger S; Alexandrov Kirill
Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase.
Science (New York, N.Y.) 2003;302(5645):646-50.
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2002: Brunsveld L; Vekemans J A J M; Hirschberg J H K K; Sijbesma R P; Meijer E W
Hierarchical formation of helical supramolecular polymers via stacking of hydrogen-bonded pairs in water.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):4977-82.
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2001: Brunsveld L; Folmer B J; Meijer E W; Sijbesma R P
Supramolecular polymers.
Chemical reviews 2001;101(12):4071-98.
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2001: Prince R B; Moore J S; Brunsveld L; Meijer E W
Cooperativity in the folding of helical m-phenylene ethynylene oligomers based upon the 'sergeants-and-soldiers' principle.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(19):4150-4.
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2001: Brunsveld L; Meijer E W; Prince R B; Moore J S
Self-assembly of folded m-phenylene ethynylene oligomers into helical columns.
Journal of the American Chemical Society 2001;123(33):7978-84.
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2000: Hirschberg J H; Brunsveld L; Ramzi A; Vekemans J A; Sijbesma R P; Meijer E W
Helical self-assembled polymers from cooperative stacking of hydrogen-bonded pairs.
Nature 2000;407(6801):167-70.
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1997: Sijbesma R P; Beijer F H; Brunsveld L; Folmer B J; Hirschberg J H; Lange R F; Lowe J K; Meijer E W
Reversible polymers formed from self-complementary monomers using quadruple hydrogen bonding.
Science (New York, N.Y.) 1997;278(5343):1601-4.
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