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James Brunton

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Escherichia coli

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Publications

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B Hamandi; Anne Holbrook; Atul Humar; James Brunton; Emmanuel A Papadimitropoulos; G G Wong; Lehana Thabane
Delay of adequate empiric antibiotic therapy is associated with increased mortality among solid-organ transplant patients.
Mark Cameron; Longsi Ran; Luoling Xu; Ali Danesh; Jesus F Bermejo Martin; Cheryl M Cameron; Matthew P Muller; Wayne L Gold; Susan E Richardson; Susan M Poutanen; Barbara M Willey; Mark E DeVries; Yuan Fang; Charit Seneviratne; Steven E Bosinger; Desmond Persad; Peter Wilkinson; Larry D Greller; Roland Somogyi; Atul Humar; Shaf Keshavjee; Marie Louie; Mark Loeb; James Brunton; Allison McGeer; David J Kelvin
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome.
Emily Stone; Tomoko Hirama; Wangxue Chen; Anna L Soltyk; James Brunton; C Roger MacKenzie; Jianbing Zhang
A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1.

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All Publications

2009: B Hamandi; Anne Holbrook; Atul Humar; James Brunton; Emmanuel A Papadimitropoulos; G G Wong; Lehana Thabane
Delay of adequate empiric antibiotic therapy is associated with increased mortality among solid-organ transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(7):1657-65.
2007: Mark Cameron; Longsi Ran; Luoling Xu; Ali Danesh; Jesus F Bermejo Martin; Cheryl M Cameron; Matthew P Muller; Wayne L Gold; Susan E Richardson; Susan M Poutanen; Barbara M Willey; Mark E DeVries; Yuan Fang; Charit Seneviratne; Steven E Bosinger; Desmond Persad; Peter Wilkinson; Larry D Greller; Roland Somogyi; Atul Humar; Shaf Keshavjee; Marie Louie; Mark Loeb; James Brunton; Allison McGeer; David J Kelvin
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome.
Journal of virology 2007;81(16):8692-706.
2007: Emily Stone; Tomoko Hirama; Wangxue Chen; Anna L Soltyk; James Brunton; C Roger MacKenzie; Jianbing Zhang
A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1.
Molecular immunology 2007;44(9):2487-91.
2004: Thierry Lobbedez; Michael Gardam; Helen Dedier; Dorothy Burdzy; Maggie Chu; Sharron Izatt; Joanne M Bargman; Sarbjit V Jassal; Stephen Vas; James Brunton; Dimitrios G Oreopoulos
Routine use of mupirocin at the peritoneal catheter exit site and mupirocin resistance: still low after 7 years.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(12):3140-3.
2004: EDDY FAN; Dale M Needham; James Brunton; Ralph Z Kern; Thomas E Stewart
West Nile virus infection in the intensive care unit: a case series and literature review.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2004;11(5):354-8.
2004: Jodie M Burton; Ralph Z Kern; William Halliday; David J Mikulis; James Brunton; Margaret Fearon; Caitlin Pepperell; Cheryl Jaigobin
Neurological manifestations of West Nile virus infection.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2004;31(2):185-93.
2003: Caitlin Pepperell; Neil Rau; Sigmund Krajden; Ralph Kern; Atul Humar; Barbara Mederski; Andrew E Simor; Donald E Low; Allison McGeer; Tony Mazzulli; Jodie Burton; Cheryl Jaigobin; Margaret Fearon; Harvey Artsob; Michael A Drebot; William Halliday; James Brunton
West Nile virus infection in 2002: morbidity and mortality among patients admitted to hospital in southcentral Ontario.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2003;168(11):1399-405.
2002: Michael Gardam; Lori L Burrows; Julianne Kus; James Brunton; Donald E Low; John M Conly; Atul Humar
Is surveillance for multidrug-resistant enterobacteriaceae an effective infection control strategy in the absence of an outbreak?
The Journal of infectious diseases 2002;186(12):1754-60.
2002: Wendy Wobeser; Monika Naus; James Brunton; Neil Heywood; A Uppaluri
TB surveillance in Canada.
Canadian journal of public health. Revue canadienne de santé publique 2002;93(4):317; author reply 317.
2002: Vince M Wolski; Anna M Soltyk; James Brunton
Tumour necrosis factor alpha is not an essential component of verotoxin 1-induced toxicity in mice.
Microbial pathogenesis 2002;32(6):263-71.
2002: Ross Davidson; Rodrigo Cavalcanti; James Brunton; Darrin J Bast; Joyce C S De Azavedo; Pamela Kibsey; Christine Fleming; Donald E Low
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
The New England journal of medicine 2002;346(10):747-50.
2002: Aparna Uppaluri; Monika Naus; Neil Heywood; James Brunton; Diane Kerbel; Wendy Wobeser
Effectiveness of the Immigration Medical Surveillance Program for tuberculosis in Ontario.
Canadian journal of public health. Revue canadienne de santé publique 2002;93(2):88-91.
2002: Anna M Soltyk; C Roger MacKenzie; Vince M Wolski; Tomoko Hirama; Pavel I Kitov; David R Bundle; James Brunton
A mutational analysis of the globotriaosylceramide-binding sites of verotoxin VT1.
The Journal of biological chemistry 2002;277(7):5351-9.
2001: Michael Gardam; James Brunton; Barbara M Willey; Allison McGeer; Donald E Low; John M Conly
A blinded comparison of three laboratory protocols for the identification of patients colonized with methicillin-resistant Staphylococcus aureus.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2001;22(3):152-6.
2001: Vince M Wolski; Anna M Soltyk; James Brunton
Mouse toxicity and cytokine release by verotoxin 1 B subunit mutants.
Infection and immunity 2001;69(1):579-83.
2000: H Ling; Neesh Pannu; A Boodhoo; Glen D Armstrong; Clifford Clark; James Brunton; Randy J Read
A mutant Shiga-like toxin IIe bound to its receptor Gb(3): structure of a group II Shiga-like toxin with altered binding specificity.
Structure (London, England : 1993) 2000;8(3):253-64.
1999: M R Weinstein; Helen Dedier; James Brunton; I Campbell; John M Conly
Lack of efficacy of oral bacitracin plus doxycycline for the eradication of stool colonization with vancomycin-resistant Enterococcus faecium.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;29(2):361-6.
1999: Darrin J Bast; L Banerjee; Clifford Clark; Randy J Read; James Brunton
The identification of three biologically relevant globotriaosyl ceramide receptor binding sites on the Verotoxin 1 B subunit.
Molecular microbiology 1999;32(5):953-60.
1998: Marie Louie; Susan Read; Andrew E Simor; J Holland; Lisa Louie; Kim Ziebell; James Brunton; J Hii
Application of multiplex PCR for detection of non-O157 verocytotoxin-producing Escherichia coli in bloody stools: identification of serogroups O26 and O111.
Journal of clinical microbiology 1998;36(11):3375-7.
1998: MD Cummings; H Ling; Glen D Armstrong; James Brunton; Randy J Read
Modeling the carbohydrate-binding specificity of pig edema toxin.
Biochemistry 1998;37(7):1789-99.
1998: H Ling; A Boodhoo; Bart Hazes; MD Cummings; Glen D Armstrong; James Brunton; Randy J Read
Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3.
Biochemistry 1998;37(7):1777-88.
1997: Darrin J Bast; J Sandhu; Nobumichi Hozumi; B Barber; James Brunton
Murine antibody responses to the verotoxin 1 B subunit: demonstration of major histocompatibility complex dependence and an immunodominant epitope involving phenylalanine 30.
Infection and immunity 1997;65(7):2978-82.
1997: Darrin J Bast; James Brunton; M A Karmali; Susan E Richardson
Toxicity and immunogenicity of a verotoxin 1 mutant with reduced globotriaosylceramide receptor binding in rabbits.
Infection and immunity 1997;65(6):2019-28.
1996: R Kaul; J A Burt; L Cork; H Dedier; M Garcia; C Kennedy; James Brunton; Mel Krajden; John M Conly
Investigation of a multiyear multiple critical care unit outbreak due to relatively drug-sensitive Acinetobacter baumannii: risk factors and attributable mortality.
The Journal of infectious diseases 1996;174(6):1279-87.
1996: L Lior; M Litt; J Hockin; C Kennedy; B A Jolley; M Garcia; G Gillis; A Humar; I Campbell; James Brunton; H Dedier; John M Conly
Vancomycin-resistant enterococci on a renal ward in an Ontario hospital.
Canada communicable disease report = Relevé des maladies transmissibles au Canada 1996;22(15):125-8.
1996: Clifford Clark; Darrin J Bast; A M Sharp; P M St Hilaire; R Agha; P E Stein; E J Toone; Randy J Read; James Brunton
Phenylalanine 30 plays an important role in receptor binding of verotoxin-1.
Molecular microbiology 1996;19(4):891-9.
1996: W L Wobeser; Mel Krajden; John M Conly; H Simpson; B Yim; M D'costa; M Fuksa; C Hian-Cheong; M Patterson; A Phillips; R Bannatyne; A Haddad; James Brunton; S Krajden
Evaluation of Roche Amplicor PCR assay for Mycobacterium tuberculosis.
Journal of clinical microbiology 1996;34(1):134-9.
1995: P G Nyholm; James Brunton; Clifford A Lingwood
Modelling of the interaction of verotoxin-1 (VT1) with its glycolipid receptor, globotriaosylceramide (Gb3).
International journal of biological macromolecules 1995;17(3-4):199-204.
1995: Mel Krajden; F Bishai; C Quan; James B Mahony; James Brunton; David S Rootman; J Zhao; W Lau; G Snell; J Maurer; Steven Kesten; D Colby
Multi-organ donor transmission of hepatitis C virus to five solid organ transplant recipients and lack of transmission to corneal transplant recipients.
Clinical and diagnostic virology 1995;3(2):113-21.
1994: M T Dytoc; A Ismaili; Dana J Philpott; R Soni; James Brunton; Philip M Sherman
Distinct binding properties of eaeA-negative verocytotoxin-producing Escherichia coli of serotype O113:H21.
Infection and immunity 1994;62(8):3494-505.
1994: Mohamed A Karmali; Martin Petric; M Winkler; Martina Bielaszewska; James Brunton; NC van de Kar; T Morooka; G B Nair; Susan E Richardson; G S Arbus
Enzyme-linked immunosorbent assay for detection of immunoglobulin G antibodies to Escherichia coli Vero cytotoxin 1.
Journal of clinical microbiology 1994;32(6):1457-63.
1994: Marie Louie; Joyce C S De Azavedo; R Clarke; A Borczyk; H Lior; M Richter; James Brunton
Sequence heterogeneity of the eae gene and detection of verotoxin-producing Escherichia coli using serotype-specific primers.
Epidemiology and infection 1994;112(3):449-61.
1993: Marie Louie; Joyce C S De Azavedo; M Y Handelsman; Clifford Clark; B Ally; M Dytoc; P Sherman; James Brunton
Expression and characterization of the eaeA gene product of Escherichia coli serotype O157:H7.
Infection and immunity 1993;61(10):4085-92.
1993: M Dytoc; R Soni; F Cockerill; Joyce C S De Azavedo; Marie Louie; James Brunton; P Sherman
Multiple determinants of verotoxin-producing Escherichia coli O157:H7 attachment-effacement.
Infection and immunity 1993;61(8):3382-91.
1993: B Boyd; G Tyrrell; M Maloney; Carlton L Gyles; James Brunton; Clifford A Lingwood
Alteration of the glycolipid binding specificity of the pig edema toxin from globotetraosyl to globotriaosyl ceramide alters in vivo tissue targetting and results in a verotoxin 1-like disease in pigs.
The Journal of experimental medicine 1993;177(6):1745-53.
1993: M Dytoc; B Gold; Marie Louie; M Huesca; L Fedorko; S Crowe; Clifford A Lingwood; James Brunton; P Sherman
Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells.
Infection and immunity 1993;61(2):448-56.
1992: P E Stein; A Boodhoo; G J Tyrrell; James Brunton; Randy J Read
Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli.
Nature 1992;355(6362):748-50.
1992: G Beebakhee; Marie Louie; Joyce C S De Azavedo; James Brunton
Cloning and nucleotide sequence of the eae gene homologue from enterohemorrhagic Escherichia coli serotype O157:H7.
FEMS microbiology letters 1992;70(1):63-8.
1992: G J Tyrrell; Karam Ramotar; Baldwin Toye; B Boyd; Clifford A Lingwood; James Brunton
Alteration of the carbohydrate binding specificity of verotoxins from Gal alpha 1-4Gal to GalNAc beta 1-3Gal alpha 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):524-8.
1991: J H Hii; Carlton L Gyles; T Morooka; Mohamed A Karmali; R Clarke; SA De Grandis; James Brunton
Development of verotoxin 2- and verotoxin 2 variant (VT2v)-specific oligonucleotide probes on the basis of the nucleotide sequence of the B cistron of VT2v from Escherichia coli E32511 and B2F1.
Journal of clinical microbiology 1991;29(12):2704-9.
1991: A Boodhoo; Randy J Read; James Brunton
Crystallization and preliminary X-ray crystallographic analysis of verotoxin-1 B-subunit.
Journal of molecular biology 1991;221(3):729-31.
1991: P Sherman; F Cockerill; R Soni; James Brunton
Outer membranes are competitive inhibitors of Escherichia coli O157:H7 adherence to epithelial cells.
Infection and immunity 1991;59(3):890-9.
1990: Karam Ramotar; B Boyd; G Tyrrell; J Gariepy; Clifford A Lingwood; James Brunton
Characterization of Shiga-like toxin I B subunit purified from overproducing clones of the SLT-I B cistron.
The Biochemical journal 1990;272(3):805-11.
1990: K A Gilbride; James Brunton
Identification and characterization of a new replication region in the Neisseria gonorrhoeae beta-lactamase plasmid pFA3.
Journal of bacteriology 1990;172(5):2439-46.
1989: S DeGrandis; H Law; James Brunton; Carlton L Gyles; Clifford A Lingwood
Globotetraosylceramide is recognized by the pig edema disease toxin.
The Journal of biological chemistry 1989;264(21):12520-5.
1989: K A Gilbride; S Rosendal; James Brunton
Plasmid mediated antimicrobial resistance in Ontario isolates of Actinobacillus (Haemophilus) pleuropneumoniae.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(1):38-42.
1987: SA De Grandis; J Ginsberg; M Toone; S Climie; J Friesen; James Brunton
Nucleotide sequence and promoter mapping of the Escherichia coli Shiga-like toxin operon of bacteriophage H-19B.
Journal of bacteriology 1987;169(9):4313-9.
1987: A Huang; J Friesen; James Brunton
Characterization of a bacteriophage that carries the genes for production of Shiga-like toxin 1 in Escherichia coli.
Journal of bacteriology 1987;169(9):4308-12.
1987: Clifford A Lingwood; H Law; S Richardson; Martin Petric; James Brunton; SA De Grandis; Mohamed A Karmali
Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro.
The Journal of biological chemistry 1987;262(18):8834-9.
1986: A Huang; SA De Grandis; J Friesen; Mohamed A Karmali; Martin Petric; R Congi; James Brunton
Cloning and expression of the genes specifying Shiga-like toxin production in Escherichia coli H19.
Journal of bacteriology 1986;166(2):375-9.