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Leo Poon

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D K W Chu; J S M Peiris; Honglin Chen; Yi Guan; Leo Poon
Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats.
Stella S F Ng; Olive T W Li; Timothy K W Cheung; J S Malik Peiris; Leo Poon
Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans.
Chung-Lam Cheung; Dhanasekaran Vijaykrishna; Gavin Smith; XH Fan; JX Zhang; J Bahl; L Duan; K Huang; H Tai; Jia Wang; Leo Poon; J S M Peiris; Honglin Chen; Yi Guan
Establishment of influenza A virus (H6N1) in minor poultry species in southern China.

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All Publications

2008: D K W Chu; J S M Peiris; Honglin Chen; Yi Guan; Leo Poon
Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats.
The Journal of general virology 2008;89(Pt 5):1282-7.
2008: Stella S F Ng; Olive T W Li; Timothy K W Cheung; J S Malik Peiris; Leo Poon
Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans.
Virology journal 2008;5():2.
2007: Chung-Lam Cheung; Dhanasekaran Vijaykrishna; Gavin Smith; XH Fan; JX Zhang; J Bahl; L Duan; K Huang; H Tai; Jia Wang; Leo Poon; J S M Peiris; Honglin Chen; Yi Guan
Establishment of influenza A virus (H6N1) in minor poultry species in southern China.
Journal of virology 2007;81(19):10402-12.
2007: B Q Dong; Wei Liu; XH Fan; Dhanasekaran Vijaykrishna; X C Tang; F Gao; L F Li; G J Li; JX Zhang; L Q Yang; Leo Poon; S Y Zhang; J S M Peiris; Gavin Smith; Honglin Chen; Yi Guan
Detection of a novel and highly divergent coronavirus from asian leopard cats and Chinese ferret badgers in Southern China.
Journal of virology 2007;81(13):6920-6.
2007: Shanthi Jayawardena; Chung-Yan Cheung; Ian Barr; Kwok-Hung Chan; Honglin Chen; Yi Guan; J S M Peiris; Leo Poon
Loop-mediated isothermal amplification for influenza A (H5N1) virus.
Emerging infectious diseases 2007;13(6):899-901.
2007: Olive T W Li; Ian Barr; Connie Y H Leung; Honglin Chen; Yi Guan; J S M Peiris; Leo Poon
Reliable universal RT-PCR assays for studying influenza polymerase subunit gene sequences from all 16 haemagglutinin subtypes.
Journal of virological methods 2007;142(1-2):218-22.
2007: Ting Kin Cheung; Leo Poon
Biology of influenza a virus.
Annals of the New York Academy of Sciences 2007;1102():1-25.
2007: John M Nicholls; M C W Chan; Renee Chan; H K Wong; Chung-Yan Cheung; Dora L W Kwong; Maria P Wong; Wing Hung Chui; Leo Poon; S W Tsao; Yi Guan; J S M Peiris
Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract.
Nature medicine 2007;13(2):147-9.
2006: D K W Chu; Leo Poon; Kwok-Hung Chan; Honglin Chen; Yi Guan; Kwok-Yung Yuen; J S M Peiris
Coronaviruses in bent-winged bats (Miniopterus spp.).
The Journal of general virology 2006;87(Pt 9):2461-6.
2006: X C Tang; JX Zhang; S Y Zhang; P Wang; XH Fan; L F Li; G Li; B Q Dong; Wei Liu; Chung-Lam Cheung; KM Xu; W J Song; Dhanasekaran Vijaykrishna; Leo Poon; J S M Peiris; Gavin Smith; Honglin Chen; Yi Guan
Prevalence and genetic diversity of coronaviruses in bats from China.
Journal of virology 2006;80(15):7481-90.
2006: S I Roberton; Diana J Bell; Gavin Smith; John M Nicholls; K H Chan; Dac Tho Nguyen; P Q Tran; U Streicher; Leo Poon; H Chen; Peter Horby; M Guardo; Y Guan; J S M Peiris
Avian influenza H5N1 in viverrids: implications for wildlife health and conservation.
Proceedings. Biological sciences / The Royal Society 2006;273(1595):1729-32.
2006: Gavin Smith; T S P Naipospos; Thi Dung Nguyen; Menno D De Jong; Dhanasekaran Vijaykrishna; T B Usman; S S Hassan; T V Nguyen; T V Dao; N A Bui; Y H C Leung; Chung-Lam Cheung; Jane M Rayner; JX Zhang; LJ Zhang; Leo Poon; Kang-Sheng Li; van Vinh Chau Nguyen; Tran Tinh Hien; Jeremy Farrar; Robert G Webster; Honglin Chen; J S M Peiris; Yi Guan
Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam.
Virology 2006;350(2):258-68.
2006: Jan ter Meulen; Edward N van den Brink; Leo Poon; Wilfred Marissen; Cynthia S W Leung; Freek Cox; Chung Y Cheung; Arjen Q Bakker; Johannes A Bogaards; Els van Deventer; Wolfgang Preiser; Hans Wilhelm Doerr; Vincent T Chow; John de Kruif; J S M Peiris; Jaap Goudsmit
Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants.
PLoS medicine 2006;3(7):e237.
2006: John M Nicholls; Jagdish Butany; Leo Poon; Kwok-Hung Chan; Swan-Lip Beh; Susan Poutanen; J S M Peiris; Maria Wong
Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS.
PLoS medicine 2006;3(2):e27.
2006: Leo Poon; Bonnie W Y Wong; Edmund H T Ma; Kwok-Hung Chan; Larry M C Chow; Wimal Abeyewickreme; Noppadon Tangpukdee; Kwok Y Yuen; Yi Guan; Sornchai Looareesuwan; J S M Peiris
Sensitive and inexpensive molecular test for falciparum malaria: detecting Plasmodium falciparum DNA directly from heat-treated blood by loop-mediated isothermal amplification.
Clinical chemistry 2006;52(2):303-6.
2006: Leo Poon
SARS and other coronaviruses in humans and animals.
Advances in experimental medicine and biology 2006;581():457-62.
2006: Vera S F Chan; Kelvin Y K Chan; Yongxiong Chen; Leo Poon; Annie N Y Cheung; Bojian Zheng; Kwok-Hung Chan; William Mak; Hextan Y S Ngan; Xiaoning Xu; Gavin Screaton; Paul K H Tam; Jonathan M Austyn; Li Chong Chan; Shea Ping Yip; Malik Peiris; Ui-Soon Khoo; Chen-Lung S Lin
Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection.
Nature genetics 2006;38(1):38-46.
2005: Kwok-Hung Chan; V C C Cheng; Patrick C Y Woo; Susanna K P Lau; Leo Poon; Yi Guan; Wing-Hong Seto; Kwok-Yung Yuen; J S M Peiris
Serological responses in patients with severe acute respiratory syndrome coronavirus infection and cross-reactivity with human coronaviruses 229E, OC43, and NL63.
Clinical and diagnostic laboratory immunology 2005;12(11):1317-21.
2005: Leo Poon; Cynthia S W Leung; Kwok-Hung Chan; Kwok Y Yuen; Yi Guan; J S M Peiris
Recurrent mutations associated with isolation and passage of SARS coronavirus in cells from non-human primates.
Journal of medical virology 2005;76(4):435-40.
2005: Leo Poon; Bonnie W Y Wong; Kwok-Hung Chan; Stella S F Ng; Kwok Y Yuen; Yi Guan; J S M Peiris
Evaluation of real-time reverse transcriptase PCR and real-time loop-mediated amplification assays for severe acute respiratory syndrome coronavirus detection.
Journal of clinical microbiology 2005;43(7):3457-9.
2005: Susan S Chiu; Kwok-Hung Chan; Ka Wing Chu; See Wai Kwan; Yi Guan; Leo Poon; J S M Peiris
Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;40(12):1721-9.
2005: Chung-Yan Cheung; Leo Poon; Iris H Y Ng; Winsie Luk; Sin-Fun Sia; Mavis H S Wu; Kwok-Hung Chan; Kwok-Yung Yuen; Siamon Gordon; Yi Guan; J S M Peiris
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis.
Journal of virology 2005;79(12):7819-26.
2005: Ting Kin Cheung; Yi Guan; S S F Ng; Honglin Chen; C H K Wong; J S M Peiris; Leo Poon
Generation of recombinant influenza A virus without M2 ion-channel protein by introduction of a point mutation at the 5' end of the viral intron.
The Journal of general virology 2005;86(Pt 5):1447-54.
2005: Wing-Cheong Yam; Kwok-Hung Chan; Kin Hung Chow; Leo Poon; HY Lam; Kwok-Yung Yuen; Wing-Hong Seto; J S M Peiris
Clinical evaluation of real-time PCR assays for rapid diagnosis of SARS coronavirus during outbreak and post-epidemic periods.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;33(1):19-24.
2005: Leo Poon; D K W Chu; Kwok-Hung Chan; O K Wong; Trevor M Ellis; Y H C Leung; Susanna K P Lau; Patrick C Y Woo; K Y Suen; Kwok-Yung Yuen; Yi Guan; J S M Peiris
Identification of a novel coronavirus in bats.
Journal of virology 2005;79(4):2001-9.
2005: M C W Chan; Chung-Yan Cheung; Wing Hung Chui; S W Tsao; John M Nicholls; Y O Chan; Renee Chan; Hoang Thuy Long; Leo Poon; Yi Guan; J S M Peiris
Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells.
Respiratory research 2005;6():135.
2005: Leo Poon; Cynthia S W Leung; Kwok-Hung Chan; Jack H C Lee; Kwok Y Yuen; Yi Guan; J S M Peiris
Detection of human influenza A viruses by loop-mediated isothermal amplification.
Journal of clinical microbiology 2005;43(1):427-30.
2005: Patrick C Y Woo; Susanna K P Lau; Chung-Ming Chu; Kwok-Hung Chan; Hoi-Wah Tsoi; Yi Huang; Beatrice H L Wong; Rosana W S Poon; James J Cai; Winsie Luk; Leo Poon; Samson S Y Wong; Yi Guan; J S M Peiris; Kwok-Yung Yuen
Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia.
Journal of virology 2005;79(2):884-95.
2004: Chung-Ming Chu; Leo Poon; V C C Cheng; Kin-Sang Chan; I F N Hung; M M L Wong; Kwok-Hung Chan; Wah-Shing Leung; Bone S F Tang; Veronica L Chan; Woon Leung Ng; Tiong-Chee Sim; Ping-Wing Ng; Kin Ip Law; Doris M W Tse; J S M Peiris; Kwok-Yung Yuen
Initial viral load and the outcomes of SARS.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2004;171(11):1349-52.
2004: Yuanxiang Zhou; Jack H Chan; Annie Y Chan; Regina K F Chak; Elaine Y L Wong; Mee-Len Chye; J S M Peiris; Leo Poon; Eric Lam
Transgenic plant-derived siRNAs can suppress propagation of influenza virus in mammalian cells.
FEBS letters 2004;577(3):345-50.
2004: Leo Poon; Yi Guan; John M Nicholls; Kwok-Yung Yuen; J S M Peiris
The aetiology, origins, and diagnosis of severe acute respiratory syndrome.
The Lancet infectious diseases 2004;4(11):663-71.
2004: I F N Hung; V C C Cheng; A K L Wu; Bone S F Tang; Kwok-Hung Chan; Chung-Ming Chu; M M L Wong; Wai-Ting Hui; Leo Poon; Doris M W Tse; Kin-Sang Chan; Patrick C Y Woo; Susanna K P Lau; J S M Peiris; Kwok-Yung Yuen
Viral loads in clinical specimens and SARS manifestations.
Emerging infectious diseases 2004;10(9):1550-7.
2004: Dong P Han; Hyung G Kim; Young B Kim; Leo Poon; Michael W Cho
Development of a safe neutralization assay for SARS-CoV and characterization of S-glycoprotein.
Virology 2004;326(1):140-9.
2004: Kang-Sheng Li; Yi Guan; Jia Wang; Gavin Smith; KM Xu; L Duan; A P Rahardjo; Pilaipan Puthavathana; Chantanee Buranathai; Thi Dung Nguyen; A T S Estoepangestie; Arunee Chaisingh; Prasert Auewarakul; Hoang Thuy Long; N T H Hanh; Richard J Webby; Leo Poon; Honglin Chen; Kennedy F Shortridge; Kwok-Yung Yuen; Robert G Webster; J S M Peiris
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia.
Nature 2004;430(6996):209-13.
2004: Bojian Zheng; Ming-Liang He; Kin-Ling Wong; Ching Tung Lum; Leo Poon; Ying Peng; Yi Guan; Marie C M Lin; Hsiang-Fu Kung
Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma).
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004;24(7):388-90.
2004: Leo Poon; Bonnie W Y Wong; Kwok-Hung Chan; Cynthia S W Leung; Kwok-Yung Yuen; Yi Guan; J S M Peiris
A one step quantitative RT-PCR for detection of SARS coronavirus with an internal control for PCR inhibitors.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;30(3):214-7.
2004: Leo Poon; Cynthia S W Leung; Masato Tashiro; Kwok-Hung Chan; Bonnie W Y Wong; Kwok-Yung Yuen; Yi Guan; J S M Peiris
Rapid detection of the severe acute respiratory syndrome (SARS) coronavirus by a loop-mediated isothermal amplification assay.
Clinical chemistry 2004;50(6):1050-2.
2004: Yi Guan; Leo Poon; Chung-Yan Cheung; Trevor M Ellis; Wilina Lim; A S Lipatov; Kwok-Hung Chan; Katharine M Sturm-Ramirez; Chung-Lam Cheung; Y H C Leung; Kwok-Yung Yuen; Robert G Webster; J S M Peiris
H5N1 influenza: a protean pandemic threat.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):8156-61.
2004: Chung-Ming Chu; V C C Cheng; I F N Hung; M M L Wong; Kwok-Hung Chan; Kin-Sang Chan; Richard Y T Kao; Leo Poon; Chris L P Wong; Yi Guan; J S M Peiris; Kwok-Yung Yuen
Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings.
Thorax 2004;59(3):252-6.
2004: Kwok H Chan; Leo Poon; V C C Cheng; Yi Guan; I F N Hung; James Kong; Loretta Y C Yam; Wing-Hong Seto; Kwok Y Yuen; J S M Peiris
Detection of SARS coronavirus in patients with suspected SARS.
Emerging infectious diseases 2004;10(2):294-9.
2004: Geoff Sutton; Elizabeth Fry; Lester Carter; Sarah Sainsbury; thomas walter; Joanne E Nettleship; Nick S Berrow; Ray Owens; Robert Gilbert; Andrew Davidson; Stuart G Siddell; Leo Poon; Jonathan M Diprose; David Alderton; Martin Walsh; Jonathan M Grimes; David I Stuart
The nsp9 replicase protein of SARS-coronavirus, structure and functional insights.
Structure (London, England : 1993) 2004;12(2):341-53.
2004: Yi Guan; J S M Peiris; Bojian Zheng; Leo Poon; Kwok-Hung Chan; FY Zeng; C W M Chan; M N Chan; J D Chen; Ken Y C Chow; Chung Chau Hon; KH Hui; Juan Li; V Y Y Li; Yong Wang; S W Leung; Kwok-Yung Yuen; Frederick C C Leung
Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome.
Lancet 2004;363(9403):99-104.
2004: Leo Poon; Kwok-Hung Chan; On Kei Wong; Ting Kin Cheung; Iris Ng; Bojian Zheng; Wing-Hong Seto; Kwok-Yung Yuen; Yi Guan; J S M Peiris
Detection of SARS coronavirus in patients with severe acute respiratory syndrome by conventional and real-time quantitative reverse transcription-PCR assays.
Clinical chemistry 2004;50(1):67-72.
2003: Enders K.O. Ng; Pak C Ng; K L E Hon; Wai Tsoi Frankie Cheng; Emily C W Hung; Allen Chan; Rossa W K Chiu; Albert M Li; Leo Poon; David S C Hui; John S Tam; Tai Fai Fok; Y M Dennis Lo
Serial analysis of the plasma concentration of SARS coronavirus RNA in pediatric patients with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):2085-8.
2003: Leo Poon; Kwok-Hung Chan; On Kei Wong; Wing-Cheong Yam; Kwok-Yung Yuen; Yi Guan; Y M Dennis Lo; J S M Peiris
Early diagnosis of SARS coronavirus infection by real time RT-PCR.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2003;28(3):233-8.
2003: Ming-Liang He; Bojian Zheng; Ying Peng; J S M Peiris; Leo Poon; Kwok Y Yuen; Marie C M Lin; Hsiang-Fu Kung; Yi Guan
Inhibition of SARS-associated coronavirus infection and replication by RNA interference.
JAMA : the journal of the American Medical Association 2003;290(20):2665-6.
2003: Yi Guan; Bo-Jian Zheng; Y Q He; X L Liu; Z X Zhuang; Chung-Lam Cheung; Shi-Wei Luo; P H Li; LJ Zhang; Y J Guan; K M Butt; Kin-Ling Wong; Kwok Wah Chan; Wilina Lim; Kennedy F Shortridge; Kwok-Yung Yuen; J S M Peiris; Leo Poon
Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
Science (New York, N.Y.) 2003;302(5643):276-8.
2003: Julian Tanner; Rory Munro Watt; Yu-Bo Chai; Lin-Yu Lu; Marie C Lin; J S M Peiris; Leo Poon; Hsiang-Fu Kung; Jian-Dong Huang
The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.
The Journal of biological chemistry 2003;278(41):39578-82.
2003: Wing-Cheong Yam; Kwok-Hung Chan; Leo Poon; Yi Guan; Kwok-Yung Yuen; Wing-Hong Seto; J S M Peiris
Evaluation of reverse transcription-PCR assays for rapid diagnosis of severe acute respiratory syndrome associated with a novel coronavirus.
Journal of clinical microbiology 2003;41(10):4521-4.
2003: Eric J Snijder; Peter J Bredenbeek; Jessika C Dobbe; Volker Thiel; John Ziebuhr; Leo Poon; Yi Guan; Michael Rozanov; Willy Spaan; Alexander E Gorbalenya
Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage.
Journal of molecular biology 2003;331(5):991-1004.
2003: FY Zeng; C W M Chan; M N Chan; J D Chen; Ken Y C Chow; Chung Chau Hon; KH Hui; Juan Li; V Y Y Li; C Y Wang; P Y Wang; Yi Guan; Bojian Zheng; Leo Poon; Kwok-Hung Chan; Kwok-Yung Yuen; J S M Peiris; Frederick C C Leung
The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39).
Experimental biology and medicine (Maywood, N.J.) 2003;228(7):866-73.
2003: Kang-Sheng Li; KM Xu; J S M Peiris; Leo Poon; K Z Yu; Kwok-Yung Yuen; Kennedy F Shortridge; Robert G Webster; Yi Guan
Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans?
Journal of virology 2003;77(12):6988-94.
2003: Leo Poon; On Kei Wong; Kwok-Hung Chan; Winsie Luk; Kwok-Yung Yuen; J S M Peiris; Yi Guan
Rapid diagnosis of a coronavirus associated with severe acute respiratory syndrome (SARS).
Clinical chemistry 2003;49(6 Pt 1):953-5.
2003: John M Nicholls; Leo Poon; Kam C Lee; Wai Fu Ng; Sik-To Lai; Connie Y H Leung; Chung-Ming Chu; Pak-Kwan Hui; Kong Ling Mak; Wilina Lim; Kin W Yan; Kwok-Hung Chan; Ngai C Tsang; Yi Guan; Kwok Y Yuen; J S M Peiris
Lung pathology of fatal severe acute respiratory syndrome.
Lancet 2003;361(9371):1773-8.
2003: J S M Peiris; Chung-Ming Chu; V C C Cheng; Kin-Sang Chan; I F N Hung; Leo Poon; Kin Ip Law; Bone S F Tang; Timothy Yu-Wai Hon; CS Chan; Kwok-Hung Chan; J S C Ng; Bo-Jian Zheng; Woon Leung Ng; Raymond W M Lai; Yi Guan; Kwok-Yung Yuen
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.
Lancet 2003;361(9371):1767-72.
2003: J S M Peiris; Sik-To Lai; Leo Poon; Yi Guan; Loretta Y C Yam; Wilina Lim; J Nicholls; W K S Yee; W W Yan; Man Tat Cheung; V C C Cheng; Kwok-Hung Chan; Dominic N C Tsang; Raymond W H Yung; Tak-Keung Ng; Kwok-Yung Yuen
Coronavirus as a possible cause of severe acute respiratory syndrome.
Lancet 2003;361(9366):1319-25.
2003: Y M Dennis Lo; Leo Poon
The ins and outs of fetal DNA in maternal plasma.
Lancet 2003;361(9353):193-4.
2003: Yi Guan; J S M Peiris; Leo Poon; Kitman C Dyrting; Trevor M Ellis; Les D Sims; Robert G Webster; Kennedy F Shortridge
Reassortants of H5N1 influenza viruses recently isolated from aquatic poultry in Hong Kong SAR.
Avian diseases 2003;47(3 Suppl):911-3.
2002: Chung-Yan Cheung; Leo Poon; Allan Sik-Yin Lau; Winsie Luk; Yu-Lung Lau; Kennedy F Shortridge; S Gordon; Yi Guan; J S M Peiris
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
Lancet 2002;360(9348):1831-7.
2002: Leo Poon; Tse N Leung; tze lau; Katherine C K Chow; Y M Dennis Lo
Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma.
Clinical chemistry 2002;48(1):35-41.
2001: Leo Poon; T N Leung; tze lau; Y M Dennis Lo
Circulating fetal RNA in maternal plasma.
Annals of the New York Academy of Sciences 2001;945():207-10.
2001: Rossa W K Chiu; Leo Poon; tze lau; Tse N Leung; Eric M C Wong; Y M Dennis Lo
Effects of blood-processing protocols on fetal and total DNA quantification in maternal plasma.
Clinical chemistry 2001;47(9):1607-13.
2001: Michael B Leahy; DC Pritlove; Leo Poon; George G Brownlee
Mutagenic analysis of the 5' arm of the influenza A virus virion RNA promoter defines the sequence requirements for endonuclease activity.
Journal of virology 2001;75(1):134-42.
2000: Ervin Fodor; Andrea Mikulasova; Louise J Mingay; Leo Poon; George G Brownlee
Messenger RNAs that are not synthesized by RNA polymerase II can be 3' end cleaved and polyadenylated.
EMBO reports 2000;1(6):513-8.
2000: Leo Poon; Tse N Leung; tze lau; Y M Dennis Lo
Presence of fetal RNA in maternal plasma.
Clinical chemistry 2000;46(11):1832-4.
2000: Leo Poon; Ervin Fodor; George G Brownlee
Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export.
Journal of virology 2000;74(1):418-27.
1999: Leo Poon; DC Pritlove; Ervin Fodor; George G Brownlee
Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template.
Journal of virology 1999;73(4):3473-6.
1999: DC Pritlove; Leo Poon; L J Devenish; Michael B Leahy; George G Brownlee
A hairpin loop at the 5' end of influenza A virus virion RNA is required for synthesis of poly(A)+ mRNA in vitro.
Journal of virology 1999;73(3):2109-14.
1998: Leo Poon; DC Pritlove; Jane Sharps; George G Brownlee
The RNA polymerase of influenza virus, bound to the 5' end of virion RNA, acts in cis to polyadenylate mRNA.
Journal of virology 1998;72(10):8214-9.
1998: DC Pritlove; Leo Poon; Ervin Fodor; Jane Sharps; George G Brownlee
Polyadenylation of influenza virus mRNA transcribed in vitro from model virion RNA templates: requirement for 5' conserved sequences.
Journal of virology 1998;72(2):1280-6.